YAMADA SHINTARO 山田真太郎

… Alternative Names

Yamada Shintaro 山田真太郎

Less

Researcher Number	20837869
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 基礎医科学研究分野, 主席研究員 2025: 公益財団法人東京都医学総合研究所, 先端基礎医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2025: 公益財団法人東京都医学総合研究所, 先端基礎医科学研究分野, 主席研究員 2024: 京都大学, 白眉センター, 特定助教 2023: 京都大学, 生命科学研究科, 特任講師 2022: 京都大学, 医学(系)研究科(研究院), 助教 2019 – 2022: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / Transformative Research Areas, Section (III) / Basic Section 63020:Radiation influence-related Except Principal Investigator Medium-sized Section 50:Oncology and related fields
Keywords	Principal Investigator DNA修復 / DNAトポイソメラーゼ / 性ホルモン / 乳癌 / DNA二重鎖切断 / DNA損傷 / ダウン症候群 / 年齢 / 生殖細胞 / エンハンサー … More / ゲノム損傷 / 臓器特異的発癌 / II型DNAトポイソメラーゼ / DNA二重鎖切断修復 … More Except Principal Investigator 発癌 / 遺伝子発現制御 / ヒトゲノム科学 / 発がん / 遺伝子発現 / ノンコーディングRNA / エストロゲン / ATM / c-MYC / 乳がん / 早期転写応答 / 発現 / エンハンサー Less

ホルモンによる癌遺伝子の異常発現を防ぐ、ゲノム修復と早期転写応答とのクロストークPrincipal Investigator
- Principal Investigator
  
  山田真太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto University
少数の細胞で全ゲノムのDNA損傷、修復、組換え反応を網羅的に検出する技術開発Principal Investigator
- Principal Investigator
  
  山田真太郎
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
  Kyoto University
ゲノム修復の破綻によりホルモン刺激依存的に癌遺伝子が過剰発現するメカニズムの解明Principal Investigator
- Principal Investigator
  
  山田真太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto University
Identification of genomic elements that promote hormone-responsive transient expression of oncogenesPrincipal Investigator
- Principal Investigator
  
  Shintaro Yamada
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyoto University
International collaboration for comprehensive identification of carcinogenesis-related transcriptional regulatory regions (enhancers)
- Principal Investigator
  
  Murakawa Yasuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Institute of Physical and Chemical Research
Understanding mechanisms in removal of aberrant adducts from ends of genomic DNA breaks caused by radiation and other factorsPrincipal Investigator
- Principal Investigator
  
  Yamada Shintaro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] TDP2 is a regulator of estrogen-responsive oncogene expression2024
- Author(s)
  Nicholas Manguso, Minhyung Kim, Neeraj Joshi, Rasel Al Mahmud, Juan Aldaco, Ryusuke Suzuki, Felipe Cortes-Ledesma, Xiaojiang Cui, Shintaro Yamada, Shunichi Takeda, Armando Giuliano, Sungyong You and Hisashi Tanaka
- Journal Title
  
  NAR Cancer
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Journal Article] TDP2 is a regulator of estrogen-responsive oncogene expression2023
- Author(s)
  Nicholas Manguso, Minhyung Kim, Neeraj Joshi, Rasel Al Mahmud, Juan Aldaco, Ryusuke Suzuki, Felipe Cortes-Ledesma, Xiaojiang Cui, Shintaro Yamada, Shunichi Takeda, Armando Giuliano, Sungyong You and Hisashi Tanaka
- Journal Title
  
  NAR Cancer
  
  Volume: in press
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0252
[Journal Article] ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen2023
- Author(s)
  Najnin Rifat Ara、Al Mahmud Md Rasel、Rahman Md Maminur、Takeda Shunichi、Sasanuma Hiroyuki、Tanaka Hisashi、Murakawa Yasuhiro、Shimizu Naoto、Akter Salma、Takagi Masatoshi、Sunada Takuro、Akamatsu Shusuke、He Gang、Itou Junji、Toi Masakazu、Miyaji Mary、Tsutsui Kimiko M.、Keeney Scott、Yamada Shintaro
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 1 Pages: 111909-111909
- DOI
  10.1016/j.celrep.2022.111909
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06122, KAKENHI-PROJECT-21K07148, KAKENHI-PROJECT-22KF0209, KAKENHI-PROJECT-20K09539, KAKENHI-PROJECT-20KK0186
[Journal Article] Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks2022
- Author(s)
  Akter Salma、Shimba Akihiro、Ikuta Koichi、Mahmud Md. Rasel Al、Yamada Shintaro、Sasanuma Hiroyuki、Tsuda Masataka、Sone Masakatsu、Ago Yukio、Murai Kenichi、Tanaka Hisashi、Takeda Shunichi
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 1 Pages: 53-67
- DOI
  10.1111/gtc.12993
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-20K09539
[Journal Article] Restoration of ligatable "clean" double-strand break ends is the rate-limiting step in the rejoining of ionizing-radiation-induced DNA breakage.2020
- Author(s)
  Sasanuma H, Yamada S, Tsuda M, Takeda S.
- Journal Title
  
  DNA Repair (Amst)
  
  Volume: 93 Pages: 102913-102913
- DOI
  10.1016/j.dnarep.2020.102913
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-19K20449
[Presentation] ゲノム損傷修復の破綻による臓器特異的発癌機構2024
- Author(s)
  山田真太郎
- Organizer
  JSPS サンフランシスコ日本人研究者交流会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0252
[Presentation] ゲノム損傷修復の破綻による臓器特異的発癌機構2024
- Author(s)
  山田真太郎
- Organizer
  JSPS サンフランシスコ日本人研究者交流会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] A functional link between DNA double-strand break repair and the early transcriptional response to the sex hormone2023
- Author(s)
  山田真太郎
- Organizer
  Social DNAing
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KK0252
[Presentation] ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen2023
- Author(s)
  Rifat Ara Najnin, Md Rasel Al Mahmud, Md Maminur Rahman, Shunichi Takeda, Hiroyuki Sasanuma, Hisashi Tanaka, Yasuhiro Murakawa, Naoto Shimizu, Salma Akter, Masatoshi Takagi, Takuro Sunada, Shusuke Akamatsu, Gang He, Junji Itou, Masakazu Toi, Mary Miyaji, Kimiko M. Tsutsui, Scott Keeney, and Shintaro Yamada
- Organizer
  The 19th Ataxia-Telangiectasia workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] A functional link between DNA double-strand break repair and the early transcriptional response to the sex hormone2023
- Author(s)
  山田真太郎
- Organizer
  Social DNAing
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] DNA損傷修復応答の破綻による臓器特異的発がん機構2022
- Author(s)
  山田真太郎
- Organizer
  第45回日本分子生物学会年会　日本生物物理学会　共催
- Invited
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] ATM Suppresses c-Myc Overexpression in the Mammary Epithelium in Response to Estrogens2022
- Author(s)
  Rifat Najnin, Md Rasel Al Mahmud, Md Maminur Rahman, Shunichi Takeda, Hiroyuki Sasanuma, Naoto Shimizu, Salma Akter, Scott Keeney, and Shintaro Yamada
- Organizer
  Genome Integrity Discussion Group
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] ATM suppresses c-Myc overexpression in mammary epithelium in response to estrogens2022
- Author(s)
  Rifat Najnin, Md Rasel Al Mahmud, Md Maminur Rahman, Hiroyuki Sasanuma, Naoto Shimizu, Salma Akter, Yasuhiro Murakawa, Scott Keeney, Shunichi Takeda, and Shintaro Yamada
- Organizer
  86th Symposium: Genome Stability & Integrity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen2022
- Author(s)
  Rifat Ara Najnin, Md Rasel Al Mahmud, Md Maminur Rahman, Shunichi Takeda, Hiroyuki Sasanuma, Hisashi Tanaka, Yasuhiro Murakawa, Naoto Shimizu, Salma Akter, Masatoshi Takagi, Takuro Sunada, Shusuke Akamatsu, Gang He, Junji Itou, Masakazu Toi, Mary Miyaji, Kimiko M. Tsutsui, Scott Keeney, Shintaro Yamada
- Organizer
  第 40 回染色体ワークショップ第 21 回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] 細胞外シグナル特異的エンハンサーにおける TOP2 依存的ゲノム切断と転写への影響2021
- Author(s)
  山田真太郎、Md Rasel Al Mahmud、村川泰裕、武田俊一
- Organizer
  第39回染色体ワークショップ・第19回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] TOP2-dependent DSBs at extracellular signal-specific enhancers and their effects on signal-induced transcription2021
- Author(s)
  山田真太郎、Md Rasel Al Mahmud、村川泰裕、武田俊一
- Organizer
  EMBO Workshop DNA Topology in genomic transactions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148
[Presentation] Genome-wide identification of androgyne-responsive enhancers and analysis of TOP2 function in enhancers2021
- Author(s)
  山田真太郎
- Organizer
  TOPO 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07148

1. Murakawa Yasuhiro (50765469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 山口まり

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 笹沼博之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 津田雅貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 武田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAMADA SHINTARO 山田 真太郎

Yamada Shintaro 山田 真太郎

Research Projects

Research Products

Co-Researchers

ホルモンによる癌遺伝子の異常発現を防ぐ、ゲノム修復と早期転写応答とのクロストークPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

少数の細胞で全ゲノムのDNA損傷、修復、組換え反応を網羅的に検出する技術開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノム修復の破綻によりホルモン刺激依存的に癌遺伝子が過剰発現するメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of genomic elements that promote hormone-responsive transient expression of oncogenesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

International collaboration for comprehensive identification of carcinogenesis-related transcriptional regulatory regions (enhancers)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding mechanisms in removal of aberrant adducts from ends of genomic DNA breaks caused by radiation and other factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] TDP2 is a regulator of estrogen-responsive oncogene expression2024

Author(s)

Journal Title

Data Source

[Journal Article] TDP2 is a regulator of estrogen-responsive oncogene expression2023

Author(s)

Journal Title

Data Source

[Journal Article] ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological concentrations of glucocorticoids induce pathological DNA double-strand breaks2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Restoration of ligatable "clean" double-strand break ends is the rate-limiting step in the rejoining of ionizing-radiation-induced DNA breakage.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] ゲノム損傷修復の破綻による臓器特異的発癌機構2024

Author(s)

Organizer

Data Source

[Presentation] ゲノム損傷修復の破綻による臓器特異的発癌機構2024

Author(s)

Organizer

Data Source

[Presentation] A functional link between DNA double-strand break repair and the early transcriptional response to the sex hormone2023

Author(s)

Organizer

Data Source

[Presentation] ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen2023

Author(s)

Organizer

Data Source

YAMADA SHINTARO 山田真太郎

Yamada Shintaro 山田真太郎