WANG DONG ＷＡＮＧＤＯＮＧ

Researcher Number	20842983
Other IDs
Affiliation (Current)	2025: 金沢大学, ナノ生命科学研究所, 特任助教
Affiliation (based on the past Project Information) *help	2025: 金沢大学, ナノ生命科学研究所, 特任助教 2019 – 2023: 金沢大学, ナノ生命科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields
Keywords	Principal Investigator EMT / colorectal cancer / driver gene mutation / activin / gastric cancer / partial EMT / organoids / p53 mutation / Activin

Organoid study to identify the molecular mechanisms of diffuse-type gastric cancer developmentPrincipal Investigator
- Principal Investigator
  
  WANG DONG
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
The role of activin combined with different gene mutations in colorectal cancer EMTPrincipal Investigator
- Principal Investigator
  
  WANG DONG
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kanazawa University
The role of activin signaling in colorectal cancer EMT inductionPrincipal Investigator
- Principal Investigator
  
  WANG DONG
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kanazawa University

All 2023 2022

All Journal Article Presentation

[Journal Article] Frequent loss of metastatic ability in subclones of Apc , Kras , Tgfbr2 , and Trp53 mutant intestinal tumor organoids2023
- Author(s)
 Morita Atsuya、Nakayama Mizuho、Wang Dong、Murakami Kazuhiro、Oshima Masanobu
- Journal Title
 
 Cancer Science
 
 Volume: 114 Issue: 4 Pages: 1437-1450
- DOI
 10.1111/cas.15709
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-21J10379, KAKENHI-PROJECT-20K07586, KAKENHI-PROJECT-23K18236
[Journal Article] Gain-of-Function p53 Mutation Acts as a Genetic Switch for TGFβ Signaling-Induced Epithelial-to-Mesenchymal Transition in Intestinal Tumors2023
- Author(s)
  Wang Dong、Nakayama Mizuho、Hong Chang Pyo、Oshima Hiroko、Oshima Masanobu
- Journal Title
  
  Cancer Research
  
  Volume: 84 Issue: 1 Pages: 56-68
- DOI
  10.1158/0008-5472.can-23-1490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K18236, KAKENHI-PROJECT-22KF0154, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-23K24160
[Journal Article] Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models2022
- Author(s)
  Nakayama Mizuho、Wang Dong、Kok Sau Yee、Oshima Hiroko、Oshima Masanobu
- Journal Title
  
  Journal of Cancer Prevention
  
  Volume: 27 Issue: 1 Pages: 1-6
- DOI
  10.15430/jcp.2022.27.1.1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-22KF0154, KAKENHI-PROJECT-20K07585
[Journal Article] Mapping Nanomechanical Properties of Basal Surfaces in Metastatic Intestinal 3D Living Organoids with High‐Speed Scanning Ion Conductance Microscopy2022
- Author(s)
  Wang Dong、Nguyen Han Gia、Nakayama Mizuho、Oshima Hiroko、Sun Linhao、Oshima Masanobu、Watanabe Shinji
- Journal Title
  
  Small
  
  Volume: 19 Issue: 9 Pages: 2206213-2206213
- DOI
  10.1002/smll.202206213
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-21H01821, KAKENHI-PROJECT-23K24160
[Journal Article] Nano-scale physical properties characteristic to intestinal cancer cells identified by high speed-scanning ion conductance microscope2022
- Author(s)
  D. Wang, L. Sun, S. Okuda, D. Yamamoto, M. Nakayama, H. Oshima, H. Saito, Y. Kouyama, K. Mimori, T. Ando, S. Watanabe, M. Oshima
- Journal Title
  
  Biomaterials
  
  Volume: 280 Pages: 121256-121256
- DOI
  10.1016/j.biomaterials.2021.121256
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-21H01821, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-23K24164
[Journal Article] Characterization of RNF43 frameshift mutations that drive Wnt ligand‐ and R‐spondin‐dependent colon cancer2022
- Author(s)
  Yamamoto Daisuke、Oshima Hiroko、Wang Dong、Takeda Haruna、Kita Kenji、Lei Xuelian、Nakayama Mizuho、Murakami Kazuhiro、Ohama Takashi、Takemura Hirofumi、Toyota Mutsumi、Suzuki Hiromu、Inaki Noriyuki、Oshima Masanobu
- Journal Title
  
  The Journal of Pathology
  
  Volume: 257 Issue: 1 Pages: 39-52
- DOI
  10.1002/path.5868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-20H03522, KAKENHI-PROJECT-21K19421, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-20K07586
[Presentation] Gain-of-function p53 mutation with LOH promotes activin A-induced partial EMT and metastasis potential2023
- Author(s)
  Dong Wang, Mizuho Nakayama, Hiroko Oshima, Masanobu Oshima
- Organizer
  The 82th annual meeting of the Japanese cancer association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15502
[Presentation] Activin promotes intestinal tumor cell metastasis by interacting with gain-of-function mutant p532022
- Author(s)
  Dong Wang, Mizuho Nakayama, Hiroko Oshima, Masanobu Oshima
- Organizer
  The 81th annual meeting of the Japanese cancer association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15502

1. 大島正伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 安藤敏夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WANG DONG ＷＡＮＧ ＤＯＮＧ

Research Projects

Research Products

Co-Researchers

Organoid study to identify the molecular mechanisms of diffuse-type gastric cancer developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of activin combined with different gene mutations in colorectal cancer EMTPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of activin signaling in colorectal cancer EMT inductionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Frequent loss of metastatic ability in subclones of <i>Apc</i> , <i>Kras</i> , <i>Tgfbr2</i> , and <i>Trp53</i> mutant intestinal tumor organoids2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gain-of-Function p53 Mutation Acts as a Genetic Switch for TGFβ Signaling-Induced Epithelial-to-Mesenchymal Transition in Intestinal Tumors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mapping Nanomechanical Properties of Basal Surfaces in Metastatic Intestinal 3D Living Organoids with High‐Speed Scanning Ion Conductance Microscopy2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nano-scale physical properties characteristic to intestinal cancer cells identified by high speed-scanning ion conductance microscope2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of RNF43 frameshift mutations that drive Wnt ligand‐ and R‐spondin‐dependent colon cancer2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Gain-of-function p53 mutation with LOH promotes activin A-induced partial EMT and metastasis potential2023

Author(s)

Organizer

Data Source

[Presentation] Activin promotes intestinal tumor cell metastasis by interacting with gain-of-function mutant p532022

Author(s)

Organizer

Data Source

WANG DONG ＷＡＮＧＤＯＮＧ