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WANG DONG  WANG DONG

ORCIDConnect your ORCID iD *help
Researcher Number 20842983
Other IDs
Affiliation (Current) 2025: 金沢大学, ナノ生命科学研究所, 特任助教
Affiliation (based on the past Project Information) *help 2025: 金沢大学, ナノ生命科学研究所, 特任助教
2019 – 2023: 金沢大学, ナノ生命科学研究所, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / 0901:Oncology and related fields
Keywords
Principal Investigator
EMT / colorectal cancer / driver gene mutation / activin / gastric cancer / partial EMT / organoids / p53 mutation / Activin
  • Research Projects

    (3 results)
  • Research Products

    (8 results)
  • Co-Researchers

    (2 People)
  •  Organoid study to identify the molecular mechanisms of diffuse-type gastric cancer developmentPrincipal Investigator

    • Principal Investigator
      WANG DONG
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kanazawa University
  •  The role of activin combined with different gene mutations in colorectal cancer EMTPrincipal Investigator

    • Principal Investigator
      WANG DONG
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Kanazawa University
  •  The role of activin signaling in colorectal cancer EMT inductionPrincipal Investigator

    • Principal Investigator
      WANG DONG
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0901:Oncology and related fields
    • Research Institution
      Kanazawa University

All 2023 2022

All Journal Article Presentation

  • [Journal Article] Frequent loss of metastatic ability in subclones of <i>Apc</i> , <i>Kras</i> , <i>Tgfbr2</i> , and <i>Trp53</i> mutant intestinal tumor organoids2023

    • Author(s)
      Morita Atsuya、Nakayama Mizuho、Wang Dong、Murakami Kazuhiro、Oshima Masanobu
    • Journal Title

      Cancer Science

      Volume: 114 Issue: 4 Pages: 1437-1450

    • DOI

      10.1111/cas.15709

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-21J10379, KAKENHI-PROJECT-20K07586, KAKENHI-PROJECT-23K18236
  • [Journal Article] Gain-of-Function p53 Mutation Acts as a Genetic Switch for TGFβ Signaling-Induced Epithelial-to-Mesenchymal Transition in Intestinal Tumors2023

    • Author(s)
      Wang Dong、Nakayama Mizuho、Hong Chang Pyo、Oshima Hiroko、Oshima Masanobu
    • Journal Title

      Cancer Research

      Volume: 84 Issue: 1 Pages: 56-68

    • DOI

      10.1158/0008-5472.can-23-1490

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K18236, KAKENHI-PROJECT-22KF0154, KAKENHI-PROJECT-23K06662, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-23K24160
  • [Journal Article] Genetic Alterations and Microenvironment that Drive Malignant Progression of Colorectal Cancer: Lessons from Mouse and Organoid Models2022

    • Author(s)
      Nakayama Mizuho、Wang Dong、Kok Sau Yee、Oshima Hiroko、Oshima Masanobu
    • Journal Title

      Journal of Cancer Prevention

      Volume: 27 Issue: 1 Pages: 1-6

    • DOI

      10.15430/jcp.2022.27.1.1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-22KF0154, KAKENHI-PROJECT-20K07585
  • [Journal Article] Mapping Nanomechanical Properties of Basal Surfaces in Metastatic Intestinal 3D Living Organoids with High‐Speed Scanning Ion Conductance Microscopy2022

    • Author(s)
      Wang Dong、Nguyen Han Gia、Nakayama Mizuho、Oshima Hiroko、Sun Linhao、Oshima Masanobu、Watanabe Shinji
    • Journal Title

      Small

      Volume: 19 Issue: 9 Pages: 2206213-2206213

    • DOI

      10.1002/smll.202206213

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-21H01821, KAKENHI-PROJECT-23K24160
  • [Journal Article] Nano-scale physical properties characteristic to intestinal cancer cells identified by high speed-scanning ion conductance microscope2022

    • Author(s)
      D. Wang, L. Sun, S. Okuda, D. Yamamoto, M. Nakayama, H. Oshima, H. Saito, Y. Kouyama, K. Mimori, T. Ando, S. Watanabe, M. Oshima
    • Journal Title

      Biomaterials

      Volume: 280 Pages: 121256-121256

    • DOI

      10.1016/j.biomaterials.2021.121256

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H06121, KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-21H01821, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-23K24164
  • [Journal Article] Characterization of RNF43 frameshift mutations that drive Wnt ligand‐ and R‐spondin‐dependent colon cancer2022

    • Author(s)
      Yamamoto Daisuke、Oshima Hiroko、Wang Dong、Takeda Haruna、Kita Kenji、Lei Xuelian、Nakayama Mizuho、Murakami Kazuhiro、Ohama Takashi、Takemura Hirofumi、Toyota Mutsumi、Suzuki Hiromu、Inaki Noriyuki、Oshima Masanobu
    • Journal Title

      The Journal of Pathology

      Volume: 257 Issue: 1 Pages: 39-52

    • DOI

      10.1002/path.5868

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H04030, KAKENHI-PROJECT-19H03498, KAKENHI-PROJECT-20H03522, KAKENHI-PROJECT-21K19421, KAKENHI-PROJECT-21K15502, KAKENHI-PROJECT-22H00454, KAKENHI-PROJECT-20K07586
  • [Presentation] Gain-of-function p53 mutation with LOH promotes activin A-induced partial EMT and metastasis potential2023

    • Author(s)
      Dong Wang, Mizuho Nakayama, Hiroko Oshima, Masanobu Oshima
    • Organizer
      The 82th annual meeting of the Japanese cancer association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15502
  • [Presentation] Activin promotes intestinal tumor cell metastasis by interacting with gain-of-function mutant p532022

    • Author(s)
      Dong Wang, Mizuho Nakayama, Hiroko Oshima, Masanobu Oshima
    • Organizer
      The 81th annual meeting of the Japanese cancer association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K15502
  • 1.  大島 正伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 2.  安藤 敏夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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