Kyogoku Yorihiko 京極自彦

Researcher Number	20849400
Other IDs
Affiliation (Current)	2025: 東北大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東北大学, 大学病院, 助教 2022 – 2023: 東北大学, 大学病院, 助教 2021: 東北大学, 大学病院, 特任助手 2020: 東北大学, 医学系研究科, 非常勤講師
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator CD161+Treg / 既喫煙喘息 / 活性窒素種 / tRNA修飾 / 活性イオウ分子種 / TH17細胞 / CD161+mTreg / レドックス不均衡 / ニトロ化ストレス / RSS … More / HDAC2 / バイオマーカー / レドックス / パースルフィド / 喘息とCOPDのオーバーラップ / ステロイド抵抗性 / ACO / 活性窒素種（RNS) / 活性イオウ分子種（RSS） Less

既喫煙喘息の難治化とCD161+mTreg及びtRNA修飾との関連の検討Principal Investigator
- Principal Investigator
  
  京極自彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
既喫煙喘息におけるレドックスバランスと炎症基盤の観点から見た新規治療戦略の検討Principal Investigator
- Principal Investigator
  
  京極自彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
The role of novel redox molecules in the airway of patients with ACOPrincipal Investigator
- Principal Investigator
  
  Kyogoku Yorihiko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Identification of Siglec-1-negative alveolar macrophages with pro-inflammatory phenotypes in chronic obstructive pulmonary disease2024
- Author(s)
  Saito Takuya、Fujino Naoya、Kyogoku Yorihiko、Yamada Mitsuhiro、Okutomo Koji、Ono Yoshinao、Konno Shuichi、Endo Takuto、Itakura Koji、Matsumoto Shuichiro、Sano Hirohito、Aizawa Hiroyuki、Numakura Tadahisa、Onodera Katsuhiro、Okada Yoshinori、Hussell Tracy、Ichinose Masakazu、Sugiura Hisatoshi
- Journal Title
  
  American Journal of Physiology-Lung Cellular and Molecular Physiology
  
  Volume: - Issue: 6 Pages: L672-L686
- DOI
  10.1152/ajplung.00303.2023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16160, KAKENHI-PROJECT-23K07619
[Journal Article] Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma2022
- Author(s)
  Itakura Koji、Fujino Naoya、Kamide Yosuke、Saito Ikuo、Yamada Mitsuhiro、Okutomo Koji、Tsukita Yoko、Saito Takuya、Ichikawa Tomohiro、Numakura Tadahisa、Kyogoku Yorihiko、Aizawa Hiroyuki、Ono Yoshinao、Matsumoto Shuichiro、Hussell Tracy、Taniguchi Masami、Ichinose Masakazu、Sugiura Hisatoshi
- Journal Title
  
  Allergol. Int.
  
  Volume: 71 Issue: 3 Pages: 383-394
- DOI
  10.1016/j.alit.2022.02.010
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16160, KAKENHI-PROJECT-20H03684, KAKENHI-PROJECT-20K08558
[Journal Article] Longitudinal Relationship Between Growth Differentiation Factor 11 and Physical Activity in Chronic Obstructive Pulmonary Disease2021
- Author(s)
  Tanaka Rie、Koarai Akira、Yamada Mitsuhiro、Fujino Naoya、Ichikawa Tomohiro、Numakura Tadahisa、Onodera Katsuhiro、Kyogoku Yorihiko、Tamada Tsutomu、Miura Motohiko、Minakata Yoshiaki、Ichinose Masakazu、Sugiura Hisatoshi
- Journal Title
  
  International Journal of Chronic Obstructive Pulmonary Disease
  
  Volume: Volume 16 Pages: 999-1006
- DOI
  10.2147/copd.s301690
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15916, KAKENHI-PROJECT-20K17208, KAKENHI-PROJECT-20H03684, KAKENHI-PROJECT-19K08662, KAKENHI-PROJECT-21K08148
[Journal Article] PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite2021
- Author(s)
  Saito Tsutomu、Ichikawa Tomohiro、Numakura Tadahisa、Yamada Mitsuhiro、Koarai Akira、Fujino Naoya、Murakami Koji、Yamanaka Shun、Sasaki Yusaku、Kyogoku Yorihiko、Itakura Koji、Sano Hirohito、Takita Katsuya、Tanaka Rie、Tamada Tsutomu、Ichinose Masakazu、Sugiura Hisatoshi
- Journal Title
  
  Respiratory Research
  
  Volume: 22 Issue: 1 Pages: 63-63
- DOI
  10.1186/s12931-021-01663-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03684, KAKENHI-PROJECT-18K08134, KAKENHI-PROJECT-18K08137, KAKENHI-PROJECT-20K17208, KAKENHI-PROJECT-21K08148
[Presentation] 喘息におけるCD161+制御性T細胞のトランスクリプトーム解析2023
- Author(s)
  京極自彦
- Organizer
  第72回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-22K16160
[Presentation] CD4+ T細胞の活性化における新規活性イオウ分子種産生酵素の役割解明2021
- Author(s)
  沼倉忠久，山田充啓，佐々木優作，鈴木　歩，京極自彦，田中里江，赤池孝章，石井直人，一ノ瀬正和，杉浦久敏
- Organizer
  第61回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K17208
[Presentation] The role of the principal cysteine persulfi de synthase in the innateimmunity of type 2 airway infl ammation2021
- Author(s)
  Ayumi Suzuki, Mitsuhiro Yamada, Tadahisa Numakura, Yusaku Sasaki, Yorihiko Kyogoku, Rie Tanaka, Ayumi Mitsune, Yuko Okuyama, Naoto Ishii, Takaaki Akaike, Masakazu Ichinose, Hisatoshi Sugiura
- Organizer
  第70回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-20K17208

1. SUGIURA Hisatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 小野寺克洋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kyogoku Yorihiko 京極 自彦

Research Projects

Research Products

Co-Researchers

既喫煙喘息の難治化とCD161+mTreg及びtRNA修飾との関連の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

既喫煙喘息におけるレドックスバランスと炎症基盤の観点から見た新規治療戦略の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of novel redox molecules in the airway of patients with ACOPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of Siglec-1-negative alveolar macrophages with pro-inflammatory phenotypes in chronic obstructive pulmonary disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased expression of airway epithelial Axl is associated with eosinophilic inflammation in severe asthma2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Longitudinal Relationship Between Growth Differentiation Factor 11 and Physical Activity in Chronic Obstructive Pulmonary Disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PGC-1α regulates airway epithelial barrier dysfunction induced by house dust mite2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 喘息におけるCD161+制御性T細胞のトランスクリプトーム解析2023

Author(s)

Organizer

Data Source

[Presentation] CD4+ T細胞の活性化における新規活性イオウ分子種産生酵素の役割解明2021

Author(s)

Organizer

Data Source

[Presentation] The role of the principal cysteine persulfi de synthase in the innateimmunity of type 2 airway infl ammation2021

Author(s)

Organizer

Data Source

Kyogoku Yorihiko 京極自彦