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PAN YANG  潘 洋

Researcher Number 20866389
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7673-2599
Affiliation (Current) 2025: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 分子細胞生物学研究部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 56060:Ophthalmology-related
Keywords
Principal Investigator
iPS細胞 / 発症分子メカニズム / 遺伝子 / オカルト黄斑ジストロフィ / OMD / 発症機序 / 病因遺伝子 / 正常眼圧緑内障 / Splicing / Causative gene … More / causative gene / splicing / Normal-tension glaucoma / iPS cells / Ophthalmology / Mouse models / Genetic diseases Less
  • Research Projects

    (2 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (2 People)
  •  RP1L1遺伝子とそのオカルト黄斑ジストロフィ関連変異体の分子機能解析Principal Investigator

    • Principal Investigator
      潘 洋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      独立行政法人国立病院機構(東京医療センター臨床研究センター)
  •  METTL23 mutation alters histone H3R17 methylation in normal-tension glaucomaPrincipal Investigator

    • Principal Investigator
      PAN YANG
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      独立行政法人国立病院機構(東京医療センター臨床研究センター)

All 2024 2023 2022 2021 2020

All Journal Article Presentation Patent

  • [Journal Article] Role of ARMS2/HTRA1 risk alleles in the pathogenesis of neovascular age-related macular degeneration2024

    • Author(s)
      Pan Yang、Iwata Takeshi
    • Journal Title

      Taiwan Journal of Ophthalmology

      Volume: - Issue: 4 Pages: 531-539

    • DOI

      10.4103/tjo.tjo-d-23-00152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15923
  • [Journal Article] Molecular genetics of inherited normal tension glaucoma2024

    • Author(s)
      Pan Yang、Iwata Takeshi
    • Journal Title

      Indian Journal of Ophthalmology

      Volume: - Issue: Suppl 3 Pages: S335-S344

    • DOI

      10.4103/ijo.ijo_3204_23

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15923
  • [Journal Article] 正常眼圧緑内障の新しい原因遺伝子METTL23を同定2023

    • Author(s)
      潘 洋,  須賀 晶子, 木村 至, 木村 肇二郎, 峯岸 ゆり子, 中山 真央, 吉武 和敏, 家島 大介, 峰松 尚子, 山本 めぐみ, 間渕 文彦, 高本 光子, 志賀 由己浩, 新家 眞病, 柏木 賢治, 相原 一, 中澤 徹, 岩田 岳
    • Journal Title

      日眼会誌

      Volume: 127 (4) Pages: 507-507

    • Data Source
      KAKENHI-PROJECT-23K15923
  • [Journal Article] アルギニンメチル基転移酵素METTL23変異と正常眼圧緑内障2023

    • Author(s)
      潘 洋,岩田 岳
    • Journal Title

      医学のあゆみ

      Volume: 287 Pages: 24507-24508

    • Data Source
      KAKENHI-PROJECT-23K15923
  • [Journal Article] HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid2022

    • Author(s)
      Ahamed Waseem、Yu Richard Ming Chuan、Pan Yang、Iwata Takeshi、Barathi Veluchamy Amutha、Wey Yeo Sia、Tun Sai Bo Bo、Qiu Beiying、Tan Alison、Wang Xiaomeng、Cheung Chui Ming Gemmy、Wong Tien Yin、Yanagi Yasuo
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 18 Pages: 10206-10206

    • DOI

      10.3390/ijms231810206

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Journal Article] METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma2022

    • Author(s)
      Pan Yang、Suga Akiko、Kimura Itaru、Kimura Chojiro、Minegishi Yuriko、Nakayama Mao、Yoshitake Kazutoshi、Iejima Daisuke、Minematsu Naoko、Yamamoto Megumi、Mabuchi Fumihiko、Takamoto Mitsuko、Shiga Yukihiro、Araie Makoto、Kashiwagi Kenji、Aihara Makoto、Nakazawa Toru、Iwata Takeshi
    • Journal Title

      Journal of Clinical Investigation

      Volume: 132 Issue: 21

    • DOI

      10.1172/jci153589

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09689, KAKENHI-PROJECT-22K09787, KAKENHI-PROJECT-20K09786, KAKENHI-PROJECT-20K18366
  • [Journal Article] Exploring the contribution of ARMS2 and HTRA1 genetic risk factors in age-related macular degeneration2022

    • Author(s)
      Pan Yang、Fu Yingbin、Baird Paul N.、Guymer Robyn H.、Das Taraprasad、Iwata Takeshi
    • Journal Title

      Progress in Retinal and Eye Research

      Volume: online ahead of print Pages: 101159-101159

    • DOI

      10.1016/j.preteyeres.2022.101159

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Journal Article] Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in?vitro2021

    • Author(s)
      Pan Yang、Iejima Daisuke、Nakayama Mao、Suga Akiko、Noda Toru、Kaur Inderjeet、Das Taraprasad、Chakrabarti Subhabrata、Guymer Robyn H.、DeAngelis Margaret M.、Yamamoto Megumi、Baird Paul N.、Iwata Takeshi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 296 Pages: 100456-100456

    • DOI

      10.1016/j.jbc.2021.100456

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09432, KAKENHI-PROJECT-20K18366
  • [Patent] 家族性正常眼圧緑内障の診断補助方法、診断キット及びバイオマーカー2021

    • Inventor(s)
      潘 洋, 岩田 岳, 木村 至
    • Industrial Property Rights Holder
      潘 洋, 岩田 岳, 木村 至
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] Functional analysis of METTL23 c.84+60delAT in Normal-Tension Glaucoma2023

    • Author(s)
      Pan Yang
    • Organizer
      The 39th Asia-Pacific Academy of Ophthalmology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K15923
  • [Presentation] Dominant Mutation in METTL23 gene is responsible for Normal tension glaucoma2022

    • Author(s)
      Pan Yang
    • Organizer
      The XXVth Biennial Meeting of the International Society of Eye Research (ISER) 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] Dominant Mutation in X gene is responsible for Normal Tension Glaucoma2022

    • Author(s)
      Pan Yang
    • Organizer
      第1回NHOネットワーク共同研究 感覚器グループ会議・班会議
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] METTL23 mutation alters histone H3R17 methylation in normal-tension glaucoma2022

    • Author(s)
      Pan Yang
    • Organizer
      第15回RRM
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] The ARMS2 insertion/deletion leads to increased circulating HTRA1 in AMD patients and in vitro2021

    • Author(s)
      Yang Pan, Daisuke Iejima, Mao Nakayama, Akiko Suga, Toru Noda, Inderjeet Kaur, Taraprasad Das, Subhabrata Chakrabarti, Robyn H. Guymer, Margaret M. DeAngelis, Paul N. Baird, Takeshi Iwata
    • Organizer
      第14回RRM
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] The ARMS2 insertion/deletion leads to systemic upregulation of secreted HTRA1 levels in the blood in AMD patients2021

    • Author(s)
      Yang Pan; Akiko Suga; Toru Noda; Inderjeet Kaur; Taraprasad Das; Subhabrata Chakrabarti; Robyn H Guymer; Margaret M DeAngelis; Paul N Baird; Takeshi Iwata
    • Organizer
      2021 ARVO Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K18366
  • [Presentation] 常染色体優性遺伝による正常眼圧緑内障の新規原因遺伝子の解明2020

    • Author(s)
      潘洋1、木村至1、2、須賀晶子1、峰松尚子1、山本めぐみ1、間渕文彦3、柏木賢治3、志賀由己浩4、橋本和軌4、西口康二4、中澤徹4、高本光子5、相原一5、新家眞5、緑内障学会遺伝子研究班、岩田岳1
    • Organizer
      Japanese Glaucoam Society
    • Data Source
      KAKENHI-PROJECT-20K18366
  • 1.  SUGA Akiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 2.  峯岸 ゆり子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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