Kubo Shintaroh 久保進太郎

… Alternative Names

久保進太郎クボシンタロウ

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Researcher Number	20874902
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究所, 基礎科学特別研究員 2025: 東京大学, 大学院工学系研究科(工学部), 特任研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 東京大学, 大学院医学系研究科(医学部), 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related
Keywords	Principal Investigator 翻訳語修飾 / キネシン / 低温電子顕微鏡 / 微小管 / 分子モーター / ダイニン / 分子動力学計算

Research Projects
(1 results)
Research Products
(13 results)

微小管の翻訳後修飾による軸糸内輸送網の制御方法に関する分子シミュレーション研究Principal Investigator
- Principal Investigator
  
  久保進太郎
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Identification of OPTN p.(Asn51Thr): A novel pathogenic variant in primary open-angle glaucoma2024
- Author(s)
  Shiga Yukihiro、Hashimoto Kazuki、Fujita Kosuke、Maekawa Shigeto、Sato Kota、Kubo Shintaroh、Kawase Kazuhide、Tokumo Kana、Kiuchi Yoshiaki、Mori Sotaro、Nakamura Makoto、Iwata Takeshi、Nishiguchi Koji M.、Nakazawa Toru
- Journal Title
  
  Genetics in Medicine Open
  
  Volume: 2 Pages: 100839-100839
- DOI
  10.1016/j.gimo.2023.100839
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070, KAKENHI-PROJECT-22KJ0505
[Journal Article] The ATPase asymmetry: Novel computational insight into coupling diverse FO motors with tripartite F12024
- Author(s)
  Kubo Shintaroh、Okada Yasushi
- Journal Title
  
  Biophysical Journal
  
  Volume: - Issue: 6 Pages: 891-900
- DOI
  10.1016/j.bpj.2024.03.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15070, KAKENHI-PROJECT-22KJ0505, KAKENHI-PROJECT-22H04926
[Journal Article] Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins2023
- Author(s)
  Kubo Shintaroh、Black Corbin S.、Joachimiak Ewa、Yang Shun Kai、Legal Thibault、Peri Katya、Khalifa Ahmad Abdelzaher Zaki、Ghanaeian Avrin、McCafferty Caitlyn L.、Valente-Paterno Melissa、De Bellis Chelsea、Huynh Phuong M.、Fan Zhe、Marcotte Edward M.、Wloga Dorota、Bui Khanh Huy
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41467-023-37868-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070, KAKENHI-PROJECT-22KJ0505
[Journal Article] FO-F1 coupling and symmetry mismatch in ATP synthase resolved in every FO rotation step2023
- Author(s)
  Kubo Shintaroh、Niina Toru、Takada Shoji
- Journal Title
  
  Biophysical Journal
  
  Volume: 122 Issue: 14 Pages: 2898-2909
- DOI
  10.1016/j.bpj.2022.09.034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15070, KAKENHI-PROJECT-22KJ0505, KAKENHI-PLANNED-20H05934, KAKENHI-PROJECT-21H02441
[Journal Article] Regulatory mechanisms of the dynein-2 motility by post-translational modification revealed by MD simulation2023
- Author(s)
  Kubo Shintaroh、Bui Khanh Huy
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-11
- DOI
  10.1038/s41598-023-28026-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070, KAKENHI-PROJECT-22KJ0505
[Presentation] Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins2023
- Author(s)
  Shintaroh Kubo
- Organizer
  EBSA2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] Molecular dynamics simulation of proton-transfer coupled rotations in ATP synthase Fo motor2023
- Author(s)
  Shintaroh Kubo
- Organizer
  TACC2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] 粗視化MD計算を用いたFOF1 ATPaseのFOモーターとF1モーターの回転対称性のミスマッチに関する理論研究2023
- Author(s)
  久保進太郎
- Organizer
  第61回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] MD simulations revealed how post-translational modification regulates dynein-2 motility2023
- Author(s)
  Shintaroh Kubo
- Organizer
  第49回内藤カンファレンス
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] 鞭毛内輸送を行うダイニンがどのように歩行する微小管を選択するのかに関する粗視化MD研究2022
- Author(s)
  久保進太郎, カーンフイブイ
- Organizer
  第60回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] POST-TRANSLATIONAL MODIFICATION OF MICROTUBULES CAN CONTROL DYNEIN-2'S ABILITY TO WALK ON A-TUBULES2022
- Author(s)
  Shintaroh Kubo, Khanh Huy Bui
- Organizer
  Biophysics at the Dawn of Exascale Computers thematic meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] How post-translational modification of tubulins controlled dynein-2 (IFT train) motility revealed by coarse-grained MD simulation2022
- Author(s)
  Shintaroh Kubo, Khanh Huy Bui
- Organizer
  Cytoskeletal Motors, Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070
[Presentation] THE THEORETICAL STUDY OF DYNEIN MOTILITY REGULATED BY TUBULIN POST TRANSLATIONAL MODIFICATION2022
- Author(s)
  Shintaroh Kubo, Khanh Huy Bui
- Organizer
  Biophysical Society 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15070

Kubo Shintaroh 久保 進太郎

久保 進太郎 クボ シンタロウ

Research Projects

Research Products

微小管の翻訳後修飾による軸糸内輸送網の制御方法に関する分子シミュレーション研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of OPTN p.(Asn51Thr): A novel pathogenic variant in primary open-angle glaucoma2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The ATPase asymmetry: Novel computational insight into coupling diverse FO motors with tripartite F12024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] FO-F1 coupling and symmetry mismatch in ATP synthase resolved in every FO rotation step2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulatory mechanisms of the dynein-2 motility by post-translational modification revealed by MD simulation2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] Native doublet microtubules from Tetrahymena thermophila reveal the importance of outer junction proteins2023

Author(s)

Organizer

Data Source

[Presentation] Molecular dynamics simulation of proton-transfer coupled rotations in ATP synthase Fo motor2023

Author(s)

Organizer

Data Source

[Presentation] 粗視化MD計算を用いたFOF1 ATPaseのFOモーターとF1モーターの回転対称性のミスマッチに関する理論研究2023

Author(s)

Organizer

Data Source

[Presentation] MD simulations revealed how post-translational modification regulates dynein-2 motility2023

Author(s)

Organizer

Data Source

[Presentation] 鞭毛内輸送を行うダイニンがどのように歩行する微小管を選択するのかに関する粗視化MD研究2022

Author(s)

Organizer

Data Source

[Presentation] POST-TRANSLATIONAL MODIFICATION OF MICROTUBULES CAN CONTROL DYNEIN-2'S ABILITY TO WALK ON A-TUBULES2022

Author(s)

Organizer

Data Source

[Presentation] How post-translational modification of tubulins controlled dynein-2 (IFT train) motility revealed by coarse-grained MD simulation2022

Author(s)

Organizer

Data Source

[Presentation] THE THEORETICAL STUDY OF DYNEIN MOTILITY REGULATED BY TUBULIN POST TRANSLATIONAL MODIFICATION2022

Author(s)

Organizer

Data Source

Kubo Shintaroh 久保進太郎

久保進太郎クボシンタロウ