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Sawazaki Taka  澤崎 鷹

ORCIDConnect your ORCID iD *help
Researcher Number 20911671
Other IDs
Affiliation (Current) 2025: 和歌山県立医科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help 2025: 和歌山県立医科大学, 薬学部, 助教
2021 – 2023: 和歌山県立医科大学, 薬学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / 0801:Pharmaceutical sciences and related fields
Keywords
Principal Investigator
アミロイド / 位置選択性 / 自己集積 / 触媒 / 基質認識 / アミノ基修飾 / 基質選択性 / 触媒反応 / タンパク質 / ドロプレット … More / 自己会合 / 単結晶X線構造解析 / 自己会合性ペプチド / 有機合成 / 液液相分離 / 化学合成 / 非天然アミノ酸 Less
  • Research Projects

    (3 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (1 People)
  •  アミロイドの分子認識による位置多様なアミノ基の選択的変換反応Principal Investigator

    • Principal Investigator
      澤崎 鷹
    • Project Period (FY)
      2025 – 2026
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Wakayama Medical University
  •  構造認識を駆動力にする触媒反応の開発と位置選択制御への展開Principal Investigator

    • Principal Investigator
      澤崎 鷹
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Wakayama Medical University
  •  Chemically stabilizing droplets associated with protein aggregationPrincipal Investigator

    • Principal Investigator
      Sawazaki Taka
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Wakayama Medical University

All 2024 2023 2022 2021

All Journal Article Presentation Patent

  • [Journal Article] Catalysis driven by an amyloid-substrate complex2024

    • Author(s)
      Sawazaki Taka, Sasaki Daisuke, Sohma Youhei
    • Journal Title

      Proceedings of the National Academy of Sciences

      Volume: 121 Issue: 19

    • DOI

      10.1073/pnas.2314704121

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K14325
  • [Journal Article] Modular synthetic strategy for N/C‐terminal protected amyloidogenic peptides2023

    • Author(s)
      Sawazaki Taka, Sohma Youhei
    • Journal Title

      Journal of Peptide Science

      Volume: 30 Issue: 3

    • DOI

      10.1002/psc.3546

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K14325, KAKENHI-PROJECT-21H02602
  • [Journal Article] Knoevenagel Condensation between 2-Methyl-thiazolo[4,5-<i>b</i>]pyrazines and Aldehydes2022

    • Author(s)
      Taka Sawazaki, Youhei Sohma, Motomu Kanai
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 70 Issue: 1 Pages: 82-84

    • DOI

      10.1248/cpb.c21-00780

    • NAID

      130008138742

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2022-01-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489
  • [Journal Article] Activatable iodinated BODIPYs for selective imaging and photodynamic disruption of amyloid structures in pathogenic bacterial biofilms2022

    • Author(s)
      Torra Joaquim、Sawazaki Taka、Bondia Patricia、Nonell Santi、Kanai Motomu、Sohma Youhei、Flors Cristina
    • Journal Title

      Sensors and Actuators B: Chemical

      Volume: 371 Pages: 132475-132475

    • DOI

      10.1016/j.snb.2022.132475

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489, KAKENHI-PROJECT-21H02602
  • [Journal Article] Chemical catalyst-promoted photooxygenation of amyloid proteins2021

    • Author(s)
      Youhei Sohma, Taka Sawazaki, Motomu Kanai
    • Journal Title

      Org. Biomol. Chem.

      Volume: 19 Issue: 46 Pages: 10017-10029

    • DOI

      10.1039/d1ob01677f

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02602, KAKENHI-PROJECT-21K20727, KAKENHI-PROJECT-20H00489
  • [Patent] アミロイド触媒を用いるアミノ基の修飾方法2023

    • Inventor(s)
      相馬洋平、澤崎鷹
    • Industrial Property Rights Holder
      公立大学法人和歌山県立医科大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2023-024577
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] アミロイドを活用した新規触媒系の開発と基質選択的反応への応用2023

    • Author(s)
      澤崎鷹、佐々木大輔、相馬洋平
    • Organizer
      第49回反応と合成の進歩シンポジウム
    • Data Source
      KAKENHI-PROJECT-23K14325
  • [Presentation] CATALYSIS DRIVEN BY AMYLOID-SUBSTRATE COMPLEX2023

    • Author(s)
      Taka Sawazaki, Daisuke Sasaki, and Youhei Sohma
    • Organizer
      第60回ペプチド討論会
    • Data Source
      KAKENHI-PROJECT-23K14325
  • [Presentation] TDP-43の病原性構造基盤の解明に向けた翻訳後修飾体化学合成経路の構築2023

    • Author(s)
      佐々木大輔、澤崎鷹、相馬洋平
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] アミロイドを活用した新規触媒系の開発と基質選択的反応への応用2023

    • Author(s)
      澤崎鷹、佐々木大輔、相馬洋平
    • Organizer
      第40回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-23K14325
  • [Presentation] アミロイドと基質の複合化を起点にする触媒反応の開発2023

    • Author(s)
      澤崎鷹、佐々木大輔、相馬洋平
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] 基質選択的な反応を実現できる新規アミロイド触媒系の開発2023

    • Author(s)
      澤崎鷹、佐々木大輔、相馬洋平
    • Organizer
      日本ケミカルバイオロジー学会 第17回年会
    • Data Source
      KAKENHI-PROJECT-23K14325
  • [Presentation] Catalysis driven by amyloid-substrate complex (CASL)2023

    • Author(s)
      Taka Sawazaki, Daisuke Sasaki, Youhei Sohma
    • Organizer
      Future Drug Discovery Empowered by Chemical Biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] アルツハイマー病患者由来のタウアミロイドに対する触媒的光酸素化2023

    • Author(s)
      梅田大輝、澤崎鷹、鈴木崇允、古田将大、三ツ沼治信、川島茂裕、堀由起子、富田泰輔、相馬洋平、金井求
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] 脳内タウアミロイドの除去を促進する化学触媒2023

    • Author(s)
      相馬 洋平、澤崎鷹、鈴木崇允、樋口真人、堀由起子、富田泰輔、金井求
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-21K20727
  • [Presentation] 細胞内タウアミロイドを光酸素化する化学触媒の開発2022

    • Author(s)
      澤崎鷹, 鈴木崇允, 堀由起子, 富田泰輔, 相馬洋平, 金井求
    • Organizer
      第48回反応と合成の進歩シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K20727
  • 1.  SOHMA Youhei
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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