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Ohara Hiroaki  大原 寛明

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大原 寛明  オオハラ ヒロアキ

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Researcher Number 20964018
Other IDs
Affiliation (Current) 2025: 京都大学, 医学研究科, 特定助教
Affiliation (based on the past Project Information) *help 2025: 京都大学, 医学研究科, 特定助教
2023: 日本赤十字社和歌山医療センター(臨床研究センター), 脳神経内科部, 医長
2022: 京都大学, 医学研究科, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 48030:Pharmacology-related / 0801:Pharmaceutical sciences and related fields
Keywords
Principal Investigator
アンチセンス核酸 / ブランチポイント / RNAスプライシング / スプライシング
  • Research Projects

    (2 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (1 People)
  •  Establishment of novel gene therapy with antisense oligonucleotide targeting branchpointsPrincipal Investigator

    • Principal Investigator
      大原 寛明
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kyoto University
  •  ブランチポイントを標的とした新たなエクソンスキップ法の確立Principal Investigator

    • Principal Investigator
      大原 寛明
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Japanese Red Cross Wakayama Medical Center
      Kyoto University

All 2023 2022

All Journal Article Presentation Patent

  • [Journal Article] Branchpoints as potential targets of exon-skipping therapies for genetic disorders2023

    • Author(s)
      Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Atsuko Hagiwara, Ryo Kurosawa, Yukiya Sako, Megumu Ogawa, Masashi Ogasawara, Satoru Noguchi, Yuichi Goto, Ryosuke Takahashi, Ichizo Nishino, Masatoshi Hagiwara
    • Journal Title

      Molecular Therapy-Nucleic Acids

      Volume: 33 Pages: 404-412

    • DOI

      10.1016/j.omtn.2023.07.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K16771, KAKENHI-PROJECT-22K20710, KAKENHI-PROJECT-22KJ2023, KAKENHI-PROJECT-20K17509
  • [Patent] ブランチポイントを標的とする偽エクソン型異常スプライシングを是正するためのアンチセンス核酸2023

    • Inventor(s)
      萩原正敏、粟屋智 就、大原寛明
    • Industrial Property Rights Holder
      萩原正敏、粟屋智 就、大原寛明
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-22K20710
  • [Patent] ブランチポイントを標的とする偽エクソン型異常スプライシングを是正するためのアンチセンス核酸2022

    • Inventor(s)
      萩原正敏、粟屋智就、大原寛明
    • Industrial Property Rights Holder
      萩原正敏、粟屋智就、大原寛明
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-188542
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-22K20710
  • [Presentation] Branch points as potential targets of exon-skipping therapies for genetic disorders2023

    • Author(s)
      Hiroaki Ohara, Motoyasu Hosokawa, Tomonari Awaya, Atsuko Hagiwara, Ryo Kurosawa, Yukiya Sako, Megumu Ogawa, Masashi Ogasawara, Satoru Noguchi, Yuichi Goto, Ryosuke Takahashi, Ichizo Nishino, Masatoshi Hagiwara
    • Organizer
      Cold Spring Harbor Laboratory Meeting "Eukaryotic mRNA Processing"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K20710
  • 1.  細川 元靖
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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