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TOHMA Masahiko  藤間 貞彦

ORCIDConnect your ORCID iD *help
Researcher Number 30001043
External Links
Affiliation (based on the past Project Information) *help 1993 – 1998: 北海道医療大学, 薬学部, 教授
1995 – 1997: 北海道医療大学, 薬学部・薬品分析科, 教授
1986 – 1992: 東日本学園大学, 薬学部, 教授
1989: 東日本学園大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Physical pharmacy
Except Principal Investigator
Physical pharmacy / Pediatrics
Keywords
Principal Investigator
ガスクロマトグラフィー質量分析 / 胎児性胆汁酸 / 先天性胆道閉鎖症 / GAS CHROMATOGRAPHY-MASS SPECTROMETRY / FETAL BILE ACID / 高速液体クロマトグラフィー / 酵素免疫測定法 / BILE ACID PROFILE / 胆汁酸生合成 / 体内動態 … More / ガスクロマトグラフィー / ENZYME IMMUNOASSAY / HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY / 新生児 / 胎児-新生児 / CONGENITAL BILIARY ATRESIA / マススクリーニング法 / 免疫学的測定法 / BILE ACID BIOSYNTHESIS / CONGENITAL DISORDER / 高速液体クロマトグラフィ- / ガスクロマトグラフィ-質量分析 / ガスクロマトグラフイ-質量分析 / 高速液体クロマトグラフイー / ガスクロマトグラフイー質量分析 / 抱合型胆汁酸 / 先天代謝異常 / Bile acid profile / Neonate / 1 beta-Hydroxylated bile acid / Immunoassay / High-performance liquid chromatography / Gas chromatography-mass spectrometry / Congenital biliary atresia / Fetal bile acid / ガスクロマトグラフィ質量分析 / 高速液体クロマトグラフィ / 新生児尿 / 胎便 / 6-水酸化胆汁酸 / 先天性胆汁酸代謝異常症 / 免疫家的測定法 / C_<27>ー胆汁酸 / 6ー水酸化胆汁酸 / 1β-水酸化胆汁酸 / 胆汁酸体内動態 / 1βー水酸化胆汁酸 / 3-OXO-DELTA^4-STEROID 5beta-REDUCTASE / 3-OXO-DELTA^4-BILE ACID / CHOLESTASIS / 酵素免疫学的測定法 / 3-オキソ-Δ^1-ステロイド5β-還元酵素 / 3-オキソ-Δ^4-ステロイド5β-還元酵素 / オキソ不飽和胆汁酸 / 酸素免疫測定法 / 質量分析 / 胆汁うっ滞 / DRIED BLOOD SPOTTED FILER PAPER / MASS SCREENING / NEONATAL LIVER DISORDER / 浸染血液乾燥濾紙 / RAT LIVER MICROSOME / 3-0X0 UNSATURATED BILE ACID / HYPERTYROSINEMIA CHOLESTASIS / BILE ACID ENZYMATIC BIOSYNTHESIS / NEONATAL LIVER DISTEASE / カニクイザル肝ミクロゾーム / 胎児性胆汁酸合成 / 未熟児 / 血液浸染乾燥濾紙 / 胆汁酸代謝異常 / ZELLWEGER SYNDROME / IMMUNOASSAY / CAPILLARY GAS CHROMATOGRAPHY / NEONATAL LIVER DESEASE / BILE ACID BIOSYNTHETIC INTERMEDIATE / キャピラリ-ガスクロマトグラフィ- / マススクリ-ニング法 / C_<27>-胆汁酸 / 先天性肝胆道疾患 / ツェルベガー症候群 / キャピラリーガスクロマトグラフィー / 新生児肝胆道疾患 / 胆汁酸生合成中間体 / HIGH PERFORMANCE LIQUID CHROMATOGRAPHY / CONJUGATED BILE ACID / 高速液体クロマトグラフイ- … More
Except Principal Investigator
HPLC / 胎児性胆汁酸 / 高速液体クロマトグラフィー / 生合成中間体 / C27-胆汁酸 / 胆汁酸代謝異常症 / High-performance liquid chromatography / Radioimmunoassay / Breast cancer / Equilenin / Comjugated estrogen / Catechol estrogen / エストロゲン依存性腫瘍 / エストロゲンレセプター / 芳香核水酸化酵素 / 電気化学検出高速液体クロマトグラフィー / 抱合型エストロゲン / ゴナドトロピン / 乳癌 / エキレニン / 抱合型エテトロゲン / ラジオイムノアッセイ / カテコールエストロゲン / stereospecificity / enzymatic specificitiy / MS / GC / biosynthesis intermediates / C27-bile acid / bile acid biosynthesis disorder / fetal bile acid / 胆汁酸代謝異常 / 立体特異性 / 酵素特異性 / GC-MS / ZELLWEGER SYNDROME / beta-OXIDATION / GAS CHROMATOGRAPHY / BIOSYNTHERTIC INTERMEDIATE / C_<27>-BILE ACID / STEREOISOMER / FETAL BILE ACID / 蛍光ラベル化 / 立体異性体 / Zellweger症候群 / β-酸化 / ガスクロマトグラフィー / 立体異性 / biliary atresia / inborn error of bile acid metabolism / unsaturated ketonic bile acid / 胆道閉鎖症 / 不飽和ケト胆汁酸 / Mass screening / Conjugated 1beta-hydroxycholic acid / Bile acids / Congenital biliary atresia / 固定化酵素 / 1β-hydroxycholic acid / 3α-hydroxysteroid dehydrogenase / 化学発光 / 高速液体クロマトグラフィ- / Tauroー1βーhydroxycholic acid / Tauro 1βーhydroxycholic acid / イムノアッセイ / 先天性肝胆道疾患 Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (16 People)
  •  STUDY OF BILE ACID BIOSYNTHESIS OF FETAL BILE ACIDS AND CONGENITAL DISORDERS

    • Principal Investigator
      KUROSAWA Takao
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
  •  ANALYSIS OF 3-OXO-DELTA^4-BILE ACIDS IN URINE OF NEONATES AND CONGENITAL DISORDERS OF BILE ACID BIOSYNTHESIS.Principal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
  •  DEVELOPMENT OF MASS SCREENING METHOD FOR CONGENITAL BILIARY ATRESIA.Principal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
  •  Research of congenital biliary atresia using analysis of DELTA^4-3-oxo-bile acids in urine

    • Principal Investigator
      KIMURA Akihiko
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Kurume University
  •  BIOSYNTHETIC RESEARCH OF FETAL BILE ACID AND ANALYSIS OF CONGENITAL DISORDER OF BILE ACID BIOSYNTHESIS

    • Principal Investigator
      KUROSAWA Takao
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
  •  PROFILE OF FETAL BILE ACID IN FETUS AND NEONATE,AND DIAGNOSIS OF NEONATAL HEPATOBILIALY DISEASESPrincipal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
  •  PROFILE OF FETAL BILE ACIDS IN FETUS AND NEONATE, THEIR CONGENITAL DIORDERSPrincipal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      HIGASHI-NIPPON-GAKUEN UNIVERSITY
  •  ANALYSIS OF THE BILE ACID PROFILES AND APPLICATION TO THE CONGENITAL LIVER DISORDERPrincipal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      HIGASHI-NIPPON-GAKUEN UNIVERSITY
  •  Developmental study for diagnostic techniques of congenital hepatobiliary disorders by fetal bile acids

    • Principal Investigator
      IKEGAWA Shigeo
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Higashi Nippon Gakuen University
  •  Profile Analysis of Fetal Bile Acids and Congenital Liver DiseasesPrincipal Investigator

    • Principal Investigator
      TOHMA Masahiko
    • Project Period (FY)
      1987 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Health Sciences University of Hokkaido
  •  The Metabolic Disposition of Catechol Estrogens and Its Significance in Clinical Chemistry

    • Principal Investigator
      NAMBARA Toshio
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      TOHOKU UNIVERSITY
  • 1.  YOSHIMURA Teruki (60220737)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  KUROSAWA Takao (50103198)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  IKEGAWA Shigeo (90111301)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  MAHARA Reijiro (30192347)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  KIMURA Akihiko (00211201)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MURAI Tsuyoshi (50260823)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  藤本 征一郎 (60001898)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  荒島 真一郎 (90002344)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  秦 温信 (10113606)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  鈴木 三佳子 (60260824)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  INOUE Toshiro (00246638)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  NAMBARA Toshio (30004534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  HONJO Hideo (30110852)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  MIYABO Susumu (70019884)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  NUMAZAWA Mitsuteru (90006338)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIZAWA Itsuo (80088864)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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