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TOHMA Masahiko
藤間 貞彦
Connect your ORCID iD
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Researcher Number
30001043
External Links
Affiliation (based on the past Project Information)
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1993 – 1998: 北海道医療大学, 薬学部, 教授
1995 – 1997: 北海道医療大学, 薬学部・薬品分析科, 教授
1986 – 1992: 東日本学園大学, 薬学部, 教授
1989: 東日本学園大学, 薬学部, 助教授
Review Section/Research Field
Principal Investigator
Physical pharmacy
Except Principal Investigator
Physical pharmacy
/
Pediatrics
Keywords
Principal Investigator
胎児性胆汁酸 / ガスクロマトグラフィー質量分析 / 高速液体クロマトグラフィー / FETAL BILE ACID / GAS CHROMATOGRAPHY-MASS SPECTROMETRY / 先天性胆道閉鎖症 / 体内動態 / 胆汁酸生合成 / BILE ACID PROFILE / 酵素免疫測定法
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/ 先天代謝異常 / 抱合型胆汁酸 / ガスクロマトグラフイー質量分析 / 高速液体クロマトグラフイー / ガスクロマトグラフイ-質量分析 / ガスクロマトグラフィ-質量分析 / 高速液体クロマトグラフィ- / CONGENITAL DISORDER / BILE ACID BIOSYNTHESIS / 免疫学的測定法 / マススクリーニング法 / CONGENITAL BILIARY ATRESIA / 胎児-新生児 / 新生児 / HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY / ENZYME IMMUNOASSAY / ガスクロマトグラフィー / 高速液体クロマトグラフイ- / CONJUGATED BILE ACID / HIGH PERFORMANCE LIQUID CHROMATOGRAPHY / 胆汁酸生合成中間体 / 新生児肝胆道疾患 / キャピラリーガスクロマトグラフィー / ツェルベガー症候群 / 先天性肝胆道疾患 / C_<27>-胆汁酸 / マススクリ-ニング法 / キャピラリ-ガスクロマトグラフィ- / BILE ACID BIOSYNTHETIC INTERMEDIATE / NEONATAL LIVER DESEASE / CAPILLARY GAS CHROMATOGRAPHY / IMMUNOASSAY / ZELLWEGER SYNDROME / 胆汁酸代謝異常 / 血液浸染乾燥濾紙 / 未熟児 / 胎児性胆汁酸合成 / カニクイザル肝ミクロゾーム / NEONATAL LIVER DISTEASE / BILE ACID ENZYMATIC BIOSYNTHESIS / HYPERTYROSINEMIA CHOLESTASIS / 3-0X0 UNSATURATED BILE ACID / RAT LIVER MICROSOME / 浸染血液乾燥濾紙 / NEONATAL LIVER DISORDER / MASS SCREENING / DRIED BLOOD SPOTTED FILER PAPER / 胆汁うっ滞 / 質量分析 / 酸素免疫測定法 / オキソ不飽和胆汁酸 / 3-オキソ-Δ^4-ステロイド5β-還元酵素 / 3-オキソ-Δ^1-ステロイド5β-還元酵素 / 酵素免疫学的測定法 / CHOLESTASIS / 3-OXO-DELTA^4-BILE ACID / 3-OXO-DELTA^4-STEROID 5beta-REDUCTASE / 1βー水酸化胆汁酸 / 胆汁酸体内動態 / 1β-水酸化胆汁酸 / 6ー水酸化胆汁酸 / C_<27>ー胆汁酸 / 免疫家的測定法 / 先天性胆汁酸代謝異常症 / 6-水酸化胆汁酸 / 胎便 / 新生児尿 / 高速液体クロマトグラフィ / ガスクロマトグラフィ質量分析 / Fetal bile acid / Congenital biliary atresia / Gas chromatography-mass spectrometry / High-performance liquid chromatography / Immunoassay / 1 beta-Hydroxylated bile acid / Neonate / Bile acid profile
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Except Principal Investigator
胎児性胆汁酸 / HPLC / Radioimmunoassay / High-performance liquid chromatography / 胆汁酸代謝異常症 / C27-胆汁酸 / 生合成中間体 / 高速液体クロマトグラフィー / 先天性肝胆道疾患 / イムノアッセイ / Tauro 1βーhydroxycholic acid / Tauroー1βーhydroxycholic acid / 高速液体クロマトグラフィ- / 化学発光 / 3α-hydroxysteroid dehydrogenase / 1β-hydroxycholic acid / 固定化酵素 / Congenital biliary atresia / Bile acids / Conjugated 1beta-hydroxycholic acid / Mass screening / 不飽和ケト胆汁酸 / 胆道閉鎖症 / unsaturated ketonic bile acid / inborn error of bile acid metabolism / biliary atresia / 立体異性 / ガスクロマトグラフィー / β-酸化 / Zellweger症候群 / 立体異性体 / 蛍光ラベル化 / FETAL BILE ACID / STEREOISOMER / C_<27>-BILE ACID / BIOSYNTHERTIC INTERMEDIATE / GAS CHROMATOGRAPHY / beta-OXIDATION / ZELLWEGER SYNDROME / GC-MS / 酵素特異性 / 立体特異性 / 胆汁酸代謝異常 / fetal bile acid / bile acid biosynthesis disorder / C27-bile acid / biosynthesis intermediates / GC / MS / enzymatic specificitiy / stereospecificity / カテコールエストロゲン / ラジオイムノアッセイ / 抱合型エテトロゲン / エキレニン / 乳癌 / ゴナドトロピン / 抱合型エストロゲン / 電気化学検出高速液体クロマトグラフィー / 芳香核水酸化酵素 / エストロゲンレセプター / エストロゲン依存性腫瘍 / Catechol estrogen / Comjugated estrogen / Equilenin / Breast cancer
Less
Research Projects
(
11
results)
Co-Researchers
(
16
People)
Project Start Year (Newest)
Project Start Year (Oldest)
STUDY OF BILE ACID BIOSYNTHESIS OF FETAL BILE ACIDS AND CONGENITAL DISORDERS
Principal Investigator
KUROSAWA Takao
Project Period (FY)
1997 – 1998
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
ANALYSIS OF 3-OXO-DELTA^4-BILE ACIDS IN URINE OF NEONATES AND CONGENITAL DISORDERS OF BILE ACID BIOSYNTHESIS.
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1996 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
DEVELOPMENT OF MASS SCREENING METHOD FOR CONGENITAL BILIARY ATRESIA.
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (B)
Research Field
Physical pharmacy
Research Institution
HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
Research of congenital biliary atresia using analysis of DELTA^4-3-oxo-bile acids in urine
Principal Investigator
KIMURA Akihiko
Project Period (FY)
1995 – 1997
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Pediatrics
Research Institution
Kurume University
BIOSYNTHETIC RESEARCH OF FETAL BILE ACID AND ANALYSIS OF CONGENITAL DISORDER OF BILE ACID BIOSYNTHESIS
Principal Investigator
KUROSAWA Takao
Project Period (FY)
1995 – 1996
Research Category
Grant-in-Aid for Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
PROFILE OF FETAL BILE ACID IN FETUS AND NEONATE,AND DIAGNOSIS OF NEONATAL HEPATOBILIALY DISEASES
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1993 – 1994
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
HEALTH SCIENCES UNIVERSITY OF HOKKAIDO
PROFILE OF FETAL BILE ACIDS IN FETUS AND NEONATE, THEIR CONGENITAL DIORDERS
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for General Scientific Research (B)
Research Field
Physical pharmacy
Research Institution
HIGASHI-NIPPON-GAKUEN UNIVERSITY
ANALYSIS OF THE BILE ACID PROFILES AND APPLICATION TO THE CONGENITAL LIVER DISORDER
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1990 – 1992
Research Category
Grant-in-Aid for Developmental Scientific Research (B)
Research Field
Physical pharmacy
Research Institution
HIGASHI-NIPPON-GAKUEN UNIVERSITY
Developmental study for diagnostic techniques of congenital hepatobiliary disorders by fetal bile acids
Principal Investigator
IKEGAWA Shigeo
Project Period (FY)
1989 – 1991
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
Higashi Nippon Gakuen University
Profile Analysis of Fetal Bile Acids and Congenital Liver Diseases
Principal Investigator
Principal Investigator
TOHMA Masahiko
Project Period (FY)
1987 – 1989
Research Category
Grant-in-Aid for General Scientific Research (C)
Research Field
Physical pharmacy
Research Institution
Health Sciences University of Hokkaido
The Metabolic Disposition of Catechol Estrogens and Its Significance in Clinical Chemistry
Principal Investigator
NAMBARA Toshio
Project Period (FY)
1986 – 1987
Research Category
Grant-in-Aid for Co-operative Research (A)
Research Field
Physical pharmacy
Research Institution
TOHOKU UNIVERSITY
# of Projects (Dsc)
# of Projects (Asc)
1.
YOSHIMURA Teruki
(60220737)
# of Collaborated Projects:
7 results
# of Collaborated Products:
0 results
2.
KUROSAWA Takao
(50103198)
# of Collaborated Projects:
6 results
# of Collaborated Products:
0 results
3.
IKEGAWA Shigeo
(90111301)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
4.
MAHARA Reijiro
(30192347)
# of Collaborated Projects:
4 results
# of Collaborated Products:
0 results
5.
KIMURA Akihiko
(00211201)
# of Collaborated Projects:
3 results
# of Collaborated Products:
0 results
6.
MURAI Tsuyoshi
(50260823)
# of Collaborated Projects:
2 results
# of Collaborated Products:
0 results
7.
藤本 征一郎
(60001898)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
8.
荒島 真一郎
(90002344)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
9.
秦 温信
(10113606)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
10.
鈴木 三佳子
(60260824)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
11.
INOUE Toshiro
(00246638)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
12.
NAMBARA Toshio
(30004534)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
13.
HONJO Hideo
(30110852)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
14.
MIYABO Susumu
(70019884)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
15.
NUMAZAWA Mitsuteru
(90006338)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
16.
YOSHIZAWA Itsuo
(80088864)
# of Collaborated Projects:
1 results
# of Collaborated Products:
0 results
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