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SHIGEMATSU Akio  重松 昭生

ORCIDConnect your ORCID iD *help
… Alternative Names

重松 昭生  シゲマツ アキオ

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Researcher Number 30037428
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2002 – 2008: UOEH, The faculty of medicine, professor, 副学長
2004: 産業医科大学, 医学部, 副学長
1995 – 2001: 産業医科大学, 医学部, 教授
1993: 産業医科大学, 医学部, 教授
1991: 産業医科大学, 医学部, 教授 … More
1988: University of Occupational and Environmental Health, School of Medicine, Department of Anesthesiology, Professor., 医学部・麻酔科, 教授
1988: 産業医科大学, 医学部・麻酔科学, 教授
1987: 産業医科大学, 麻酔科学教室, 教授
1986: 産業医科大学, 医学部・麻酔学, 教授 Less
Review Section/Research Field
Principal Investigator
Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / 麻酔学
Except Principal Investigator
Anesthesiology/Resuscitation studies / 麻酔学 / Anesthesiology/Resuscitation studies
Keywords
Principal Investigator
麻酔薬 / ケタミン / プロポフォール / Anesthetics / トラマドール / Sodium / Calcium / イオンチャンネル / GF109203X / Xenopus oocytes … More / propofol / ketamine / 静脈麻酔薬 / イオンチャネル / [^3H]-thymidine / 細胞増殖 / メサンギウム細胞 / Catecholamine secretion / Binding site / Ion channel / カテコールアミン分泌 / アセチルコリン受容体 / 副腎髄質 / Anesthetics. / Secretion / Ion channels / Catecholamine / Adrenal medulla / orexin A / Tramadol / substance P / Xenopus oocyte / G-protein coupled receptor (GPCR) / ion channels / dorsal root ganglia cells / G蛋白結合受容体 / 疼痛発生メカニズム / ハロセン / エーテル / エンフルラン / イソフルラン / ステロイド系静脈麻酔薬アルファキサロン / 電位依存性Naチャネル / オレキシンA / サブスタンスP / アフリカツメガエル卵母細胞発現系 / G蛋白共役型受容体 / 脊髄後根神経節 / 吸入麻酔薬 / muscarinic receptor / adrenal medullary cells / nicotinic acetylcholine receptor / norepinephrine transporter / alphaxalone / tramadol / neurosteroid anestheticis / 腎血流 / ノルアドレナリントランスポーター / ニコチン性アセチルコリン受容体イオンチャネル / ムスカリン受容体 / ノルエピネフリントランスポーター / ニコチン性アセチルコリン受容体イオンチャンネル / アフリカツメガエル卵母細胞系 / 副腎髄質細胞 / アルファキサロン / ステロイド系麻酔薬 / cell / protein kinase C (PKC) / [3^H] thymidine / vascular smooth muscle / anesthetics / キシロカイン / フェンタネスト / 細胞 / protein kinase C(PKC) / 血管平滑筋細胞 / Muscarinic reseptor / 5HT2A / Protein Kinase / [^3H]tymidine / mesangial cell / アフリカツメガエル卵母細胞 / ラット腎メサンギウム細胞 / protein kinase C / 〔^3H〕-thymidine / [^3]-thymidine / 燐酸化酵素 / 腎メサンギウム細胞 / デクサメデトミジン / パッチクランプ法 / 脊髄後根神経節細 / 麻酔機序 / 受容体 / 脊髄後角 / 一次痛覚神経 / 麻酔薬作用機序 / 脊髄 / 中枢神経系 / 細胞内リン酸化酵素 / ^3H-thymidine / 静脈性麻酔ケタミン / 動脈平滑筋 / 生活習慣病 / 動脈硬化 / 血管障害性動脈硬化 / 細胞内cAMP / 静脈性麻酔薬ケタミン / 血管平滑筋増殖 / サイトカイン / アドレノメヂュリン / TNF / IL-6 / IL-1 / [^3H]-thymidineの取り込み / アドレノメデュリン / 腎炎モデル / 細胞内cAMP濃度 / カラギーナン / エンドトキシン / tumor necrosis factor / nitric oxide … More
Except Principal Investigator
ハロセン / ケタミン / 麻酔薬 / プロポフォール / エンドトキシンショック / Protein Kinase C (PKC) / Toll like receptor / HSP-70 / Isoflurane / Halothane / エンフルラン / イソフルラン / アフリカツメガエル卵母細胞発現系 / 副腎髄質 / イオン・チャンネル / 静脈麻酔薬 / TNF / Enflurane / Xenopus oocyte / Protein G / Cannabinoid Receptor / Gq蛋白 / Gi / Ca^<2+>依存性Cl^-チャネル / G蛋白質共役型受容体 / Protein Kinase C(PKC) / G蛋白 / カナビノイド受容体 / MIF / Anesthesia / Oxygen burst / phagocytosis / Surgical stress / Innate immunit / 外科浸襲 / エンドトキシン感受性 / 自然免疫 / LPS / コルチゾール / IL-10 / 細菌貪食能 / TLR4 / TLR2 / 外科侵襲 / Protein kinase C / tachykinin receptors / Ennflurane / Xenopus oocytes / Gq coupled receptor / Substance preceptor / セボフルラン / イソフルレン / 疼痛機序 / タキキニンレセプター / サブスタンスーP(NK1)レセプター / Protein Kinase C / タキキニンレセプター. / Gq蛋白結合受容体 / サブスタンス-P(NK1)レセプター / liposome / vascular permeability / C12MDP / sepsis / endotoxin / lung injury / エンドトキシン / chlodronate / 肺傷害 / 肺障害 / リポソーム / マクロファージ / Cl2MDP / Human whole blood / Cytokine / Endotoxic shock / LPS Neutralizing / Bactericidal / Peptide-IgG conjugate / CAP 18 / 合成CAP18免疫グログリン / ヒト全血 / サイトカイン / 食細胞機能 / LPS中和作用 / 殺菌作用 / 合成CAP18免疫グロブリン / CAP18 / アパミン / 全身麻酔薬 / K^+ / Ca^<2+> / Na^+ / 【Ca^(2+)】 / 【Na^+】 / カテコールアミン分泌 / ドロペリドール / CGRP受容体 / サブスタンス-P受容体 / Xenous ooctes発現系 / 麻酔作用機序 / 痛み / イオンチャネル / G蛋白共役型受容体 / ムスカリン受容体 / Xenopus oocytes発現系 / 脊髄後根神経節(DRG)細胞 / 鎮痛薬 / 疼痛メカニズム / NATmRNA / ジアゼパム / チオペンタール / RT-PCR(reverse transcriptase-polymerase chain reaction)法 / ノルアドレナリントランスポーター / 下行性疼痛抑制系 / 燐酸化酵素 / アミントランスポーター / ノルアドレナリン / カテコールアミン / 副腎髄質細胞 / Ca^<2+>電流 / GABA / サイアミラル / PACAP / バゾプレッシン / 神経内分泌 / 抗TNF抗体 / 血小板活性化因子 / ロイコトルエン / カラギ-ナン Less
  • Research Projects

    (22 results)
  • Research Products

    (1 results)
  • Co-Researchers

    (29 People)
  •  The study on the G protein coupled receptors to find the new analgesicsPrincipal Investigator

    • Principal Investigator
      MINAMI Koichiro, 重松 昭生
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬作用における中枢神経系各部位の果たす役割解析Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬の動脈硬化予防作用の臨床応用を目指した研究-麻酔薬の新たなる作用の検討-Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The study of antinociceptive effects of anesthetics and analgesics using dorsal root ganglia cells.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  Innate immunity and expressions of TLRs during upper abdominal surgery

    • Principal Investigator
      OGATA Masanori
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  The effects of anesthetics and ethanol on cannabinoid receptor function.

    • Principal Investigator
      KAMOCHI Masayuki
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  The mechanisms of analgesic effects of Tramadol and AlphaxalonePrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  静脈麻酔薬のノルアドレナリントランスポーターに対する作用機序の解析

    • Principal Investigator
      相原 啓二
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Effects of Anesthetics on tachykinin Receptors Expressed in Xenopus Oocytes

    • Principal Investigator
      SATA Takeyoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health(UOEH)
  •  The effects of intravenous anesthetics on aortic smooth muscle cells proliferation in vivo and in vitroPrincipal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      Uinversity of Occupational Environmental Health (UOEH)
  •  The effect of CAP18-immunoglobulin G conjugate on endotoxin shock.

    • Principal Investigator
      OTGATA Masanori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  The effects of alveolar macrophage depletion by liposome technique on LPS-induced lung injury.

    • Principal Investigator
      KAMOCHI Masayuki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health (UOEH)
  •  The effect of anesthetics on mesangial cells proliferation via protein kinase pathway.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational Environmental Health(UOEH)
  •  腎炎モデル動物を用いた慢性腎障害に対する麻酔薬の腎保護作用の検討Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  免疫サイトカイン・神経ペプチド麻酔関連薬の視床下部神経内分泌細胞への影響

    • Principal Investigator
      井上 義崇
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  神経シナプス間隙でのニューロトランスミッター動態に及ぼす全身麻酔薬の作用の解析

    • Principal Investigator
      佐多 竹良
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  麻酔薬の腎機能保護作用の解析-ラット腎培養メサンギウム細胞を用いた検討-Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  サイトカインのカラギーナン微量エンドトキシンショックに及ぼす影響Principal Investigator

    • Principal Investigator
      重松 昭生
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Anesthesiology/Resuscitation studies
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  エンドトキシンショックによる多臓器不全モデルの確立とその病態の解析

    • Principal Investigator
      OTGATA Masanori
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  副腎髄質の電位依存性Kチャンネル並びにCa依存性Kチャンネルに対する麻酔薬の影響

    • Principal Investigator
      緒方 政則
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan
  •  Action of anesthetics on acetylcholine receptor and voltage-dependent Na channel in cultured adrenal medullary cells.Principal Investigator

    • Principal Investigator
      SHIGEMATSU Akio, 高良 裕
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, School of Medicine.
  •  Naチャンネル,Caチャンネル並びにKチャンネルに対する麻酔薬の影響-培養副腎髄

    • Principal Investigator
      TAKARA Hiroshi
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      麻酔学
    • Research Institution
      University of Occupational and Environmental Health, Japan

All 2007

All Journal Article

  • [Journal Article] Dexmedetomidine inhibits muscarinic type 3 receptors expressed in Xenopus oocytes and muscarine-induced intracellular Ca^<2+> elevation in cultured rat dorsal root ganglia cells.2007

    • Author(s)
      Takizuka A, Minami K, Uezono Y, Horishita T, Yokoyama T, Shiraishi M, Sakurai T, Shigematsu A, Ueta Y
    • Journal Title

      Naunyn Schmiedebergs Arch Pharmacol. 375(5)(Epub)

      Pages: 293-301

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390410
  • 1.  MINAMI Koichiro (70279347)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 1 results
  • 2.  SATA Takeyoshi (60128030)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  UEZONO Yasuhito (20213340)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results
  • 4.  OTGATA Masanori (70169176)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  TAKARA Hiroshi (30148952)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  HORISHITA Takahumi (40369070)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 7.  SHIRAISHI Munehiro (40389458)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  WADA Akihiko (30131949)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KAWASAKI Takashi (60299633)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  UETA Yoichi (10232745)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  KOHRIYAMA Kazuaki (80258623)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KAMOCHI Masayuki (90204643)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  青山 和義 (10212391)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  SEO Norimasa (40093257)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOGA Kazunori (20248587)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  ISHIMURA Hiroshi (40289583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  WATANABE Hiroyuki (90220920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SAGATA Kenichiro (30331002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  NANDATE Kouichiroh (50299632)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  松本 尚浩 (10239105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  末永 俊郎 (90269069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  井上 義崇 (60279346)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  山下 博 (00030841)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  柳原 延章 (80140896)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  相原 啓二 (70258622)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  瀬川 賀世子 (70289578)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  横山 徹 (80425321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  瓜生 佳代 (20309975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  尾方 純一 (50352331)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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