KAWASHIMA Yoshiaki 川島嘉明

… Alternative Names

川島嘉明カワシマヨシアキ

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Researcher Number	30082978
Other IDs
External Links
Affiliation (Current)	2025: 岐阜薬科大学, その他部局等, 名誉教授
Affiliation (based on the past Project Information) *help	2006 – 2008: 愛知学院大学, 薬学部, 教授 2000 – 2004: 岐阜薬科大学, 薬学部, 教授 1995 – 1998: 岐阜薬科大学, 薬学部, 教授 1986 – 1991: Gifu Pharmaceutical University ・ Professor, 薬学部, 教授
Review Section/Research Field	Principal Investigator 広領域 / Physical pharmacy Except Principal Investigator Physical pharmacy / Thoracic surgery / Respiratory organ internal medicine / Circulatory organs internal medicine
Keywords	Principal Investigator surface modification / glycolide copolymer / ナノスフェア / 経肺投与 / 粉末吸入製剤 / spherical crystallization / 晶析 / 球形晶析法 / Suspension / Bioavailability … More / Controlled release / Amorphous / Microspher / アクリル酸ポリマー / 多形 / サスペンション / 生物学的利用能 / コントロールリリース / アモルファス / マイクロスフィアー / plasmid DNA / chitosan / intra-articular injection / pulmonary administration / nanosphere / D,L-lactide / ナノ結晶 / 抗リュウマチ薬 / 難水溶性薬物 / 経肺投与製剤用溶出試験法 / プロピオン酸ベクロメタゾン / エマルション溶媒核酸法 / 関節注射用徐放性製剤 / ポリスチレンナノスフェア / 共焦点レーザー走査顕微鏡 / 粘膜付着性製剤 / 原子間力顕微鏡 / 肺上皮癌細胞 / プラスミドDNA / キトサン / 表面修飾 / 関節内注射 / ポリ乳酸・グリコール酸 / insulin / nebulizer / lactide / nanocapsule / aerosolized aqueous suspension / pulmonary delivery / dry powder inhalation / ペフチド / 超音波ネブライザー / 表面改質法 / ペプチド / ツインインピンジャー / 表面改質 / インスリン / ネブライザー / 乳酸・グリコール酸共重合体 / 高分子ナノカプセル / 水性懸濁エアゾール / particle design / residence time in stomach / drug release rate / emulsion-solvent-diffusion method / microballoon / floating system / controlled release system / 流動性 / せん断付着力 / 比重 / 空隙率 / 微小中空粒子 / 造粒 / ラジオグラフィ- / 浮遊性 / コントロ-ルリリ-ス / 製剤設計 / X線ラジオグラフィ- / 血中濃度 / 微小中空浮遊型デバイス / エマルションー溶媒ー拡散法 / 粒子設計 / 胃内滞留時間 / 薬物放出速度 / エマルション・溶媒・拡散法 / マイクロバル-ン / 浮遊システム / 薬物放出制御システム … More Except Principal Investigator 粘膜付着 / リポソーム / ナノテクノロジー / 表面修飾 / nanosphere / liposome / ナノスフェア / Freeze-Thawing of Liposomes / Modified REV Method / Fluidity of Liposomes / Size Control of Liposomes / Lyophilization of Liposomes / 蛋白のリポソームへの内包 / リポソームの凍結融解 / 改逆相蒸発法 / リポソームの流動性 / リポソームの粒径調整 / リポソームの凍結乾燥 / nanotechnology / vein graft disease / 静脈グラフト / ドラッグ・デリバリー・システム / 生体適合材料 / 心臓大血管外科学 / drug permeability / chitosan / Caco2 cell / mucoadhesion / liposomes / nanoparticles / メソポーラス / 微粒子製剤 / 経口免疫 / 薬物膜透過 / カルシトニン / キトサン / Caco2細胞 / 微粒子 / cancer cell / Targeting / mires adhesion / surface modification / がん細胞 / 体内動態制御 / peptide / insulin / mucoadhesive / oral administration / 吸収 / 薬物担体 / ナノスフェア- / ペプチド / インスリン / 経口投与 / hemolysis / acute toxicity / lipiodol / epirubicin hydrochloride / transcatheter arterial ambolization therapy / w emulsion / o / w / 肺水腫 / 塩酸エピルビシン / 化学塞栓療法 / Wエマルジョン / 溶血性 / 急性毒性 / リピオドール / 塩酸エピルビジン / 経カテーテル動脈塞栓療法 / Wエマルション / O / W / 老化 / 幹細胞 / 細気管支上皮細胞 / アポトーシス / 再生 / 細気管支 / 肺線維症 / 肺損傷 / 動脈硬化 / 再狭窄 / DDS / 血管病態学 Less

formulation of bioabsorbable nanoparticle-eluting stent and Mg-Ca alloy stent
- Principal Investigator
  
  EGASHIRA Kensuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
The role of small airways in lung injury and regeneration, and the treatment strategy using nanotechnology
- Principal Investigator
  
  KUWANO Kazuyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Jikei University School of Medicine
Nanoparticle-mediated Intracellular Delivery of Imatinib Mesylate(STI571) Ex Vivo Suppresses Vein Grail Neointima Formation
- Principal Investigator
  
  SHIOSE Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyushu University
Studies on nano-particulate systems and their bio-response for drug delivery
- Principal Investigator
  
  TAKEUCHI Hirofumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University
Organization of nanoparticulate system by spherical crystallization for poorly absorbable drugPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Yoshiaki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Gifu Pharmaceutical University
Studies on controlled biodistribution of submicron-sized drug-carriers with surface modification and its controlling mechanism
- Principal Investigator
  
  TALEUCHI Hirofumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University
Development of pulmonary drug delivery system with dry powder and aqueous suspension aerosolsPrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Yoshiaki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  GIFU PHARMACEUTICAL UNIVERSITY
Development and application of novel w/o/w emulsion for the chemoembolization therapy of hepatocellular carcinoma
- Principal Investigator
  
  HINO Tomoaki
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University
DESIGN AND EVALUATION OF MUCOADHESIVE MICROPARTICULATE DRUG CARRIERS FOR ORAL ADMINISTRATION OF PEPTIDE DRUGS
- Principal Investigator
  
  TAKEUCHI Hirofumi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  GIFU PHARMACEUTICAL UNIVERSITY
Development of novel controlled drug release system with floating micro-hollow spherePrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Yoshiaki
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  広領域
- Research Institution
  Gifu Pharmaceutical University
Development of a Novel Preparation Method of High Energy MicrospherePrincipal Investigator
- Principal Investigator
  
  KAWASHIMA Y
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  広領域
- Research Institution
  Gifu Pharmaceutical University
Freeze-Drying and Stabilization of Liposomes Encapsulating Drug and Enzyme
- Principal Investigator
  
  HANDA Tetsurou
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Gifu Pharmaceutical University

All 2009 2008 2007 2005 2004 2003

All Journal Article Book

[Book] ナノテクノロジーのDDSへの応用"ドラッグデリバリーシステムの新展開"(永井恒司監修)2004
- Author(s)
  竹内洋文, 川島嘉明
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370731
[Journal Article] Therapeutic Neovascularization by Nanotechnology-Mediated Cell-Selective Delivery of Pitavastatin into the Vascular Endothelium2009
- Author(s)
  Kubo M, Egashira K, Inoue T, Koga J, Oda S, Chen L, Nakano K, Matoba T, Kawashima Y, Hara K, Tsujimoto H, Sueishi K, Tominaga R, Sunagawa K
- Journal Title
  
  Atheroscler Thromb Vasc Biol. (in press)
- Data Source
  KAKENHI-PROJECT-19390216
[Journal Article] Local Delivery of Imatinib Mesylate (STI571) Incorporated Nanoparticle Ex Vivo Suppresses Vein Graft Neointima Formation2008
- Author(s)
  Kimura S, Egashira K, Nakano K, Iwata E, Miyagawa M, Tsujimoto H, Hara K, Kawashima Y, Tominaga R,Sunagawa K
- Journal Title
  
  Circulation 118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390216
[Journal Article] Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery2008
- Author(s)
  Yamamoto H, Kawashima Y. et.al.
- Journal Title
  
  Int J Pharm 354
  
  Pages: 210-216
- Data Source
  KAKENHI-PROJECT-19390225
[Journal Article] PLGAナノスフェアを用いた遺伝子デリバリーシステムの開発2007
- Author(s)
  Yamamoto H, Kawashima Y. et.al.
- Journal Title
  
  YAKUGAKU ZASSHI 127
  
  Pages: 1541-1548
- NAID
  110006402943
- Data Source
  KAKENHI-PROJECT-19390225
[Journal Article] Mucoadhesive properties of Carbopol or chitosan-coated liposomes and their effectiveness in the oral administration of calcitonin to rats2005
- Author(s)
  Takeuchi, H., Thongborisute, J., Matsui, Y., Sugihara, H.Yamamoto, H., Kawashima, Y.
- Journal Title
  
  Advanced Drug Delivery Rievew (accepted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370731
[Journal Article] Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems2005
- Author(s)
  H.Takeuchi, J.Thongborisute, Y.Matsui, H.Sugihara, H.Yamamoto, Y.Kawashima
- Journal Title
  
  Advanced Drug Delivery Rievew accepted
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370731
[Journal Article] Novel mucoadhesion tests for polymers and polymer-coated particles to design optimal mucoadhesive drug delivery systems2005
- Author(s)
  H.Takeuchi, J.Thongborisute, Y.Matsui, H.Sugihara, H.Yamamoto, Y.Kawashima
- Journal Title
  
  Advanced Drug Delivery Rievew (accepted)
- Data Source
  KAKENHI-PROJECT-14370731
[Journal Article] Mucoadhesive properties of Carbopol or chitosan-coated liposomes and their effectiveness in the oral administration of calcitonin to rats2003
- Author(s)
  Takeuchi, H., Nagira, S., Yamamoto, H, Kawashima, Y.
- Journal Title
  
  Journal of Control Release 86
  
  Pages: 235-242
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370731

1. TAKEUCHI Hirofumi (50171616)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
2. YAMAMOTO Hiromitu (30275094)

# of Collaborated Projects: 6 results

# of Collaborated Products: 6 results
3. HINO Tomoaki (90208778)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. NIWA Toshiyuki (30198543)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. HANDA Tetsurou (00025719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. EGASHIRA Kensuke (60260379)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. NAKANO Kaku (30420607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. ICHIKI Toshihiro (80311843)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. MATOBA Tetsuya (20448426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. KUWANO Kazuyoshi (40205266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAMADA Naoki (00423567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MAEYAMA Takashige (40380456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHIOSE Akira (30363336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MASUDA Munetaka (10190365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOMITA Yukihiro (90180174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TOMINAGA Ryuji (70136464)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWASHIMA Yoshiaki 川島 嘉明

川島 嘉明 カワシマ ヨシアキ

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Organization of nanoparticulate system by spherical crystallization for poorly absorbable drugPrincipal Investigator

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Development of pulmonary drug delivery system with dry powder and aqueous suspension aerosolsPrincipal Investigator

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Development of novel controlled drug release system with floating micro-hollow spherePrincipal Investigator

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Development of a Novel Preparation Method of High Energy MicrospherePrincipal Investigator

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[Book] ナノテクノロジーのDDSへの応用"ドラッグデリバリーシステムの新展開"(永井恒司監修)2004

Author(s)

Publisher

Description

Data Source

[Journal Article] Therapeutic Neovascularization by Nanotechnology-Mediated Cell-Selective Delivery of Pitavastatin into the Vascular Endothelium2009

Author(s)

Journal Title

Data Source

[Journal Article] Local Delivery of Imatinib Mesylate (STI571) Incorporated Nanoparticle Ex Vivo Suppresses Vein Graft Neointima Formation2008

Author(s)

KAWASHIMA Yoshiaki 川島嘉明

川島嘉明カワシマヨシアキ