SUGATANI JUNKO 菅谷純子

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SUGATANI Junko 菅谷純子

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Researcher Number	30098131
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2015: 静岡県立大学, 薬学部, 教授 2008 – 2012: University of Shizuoka, 薬学部, 教授 2007: University of Shizuoka, Faculty of Permaceutical Sience, Assistant professor 2002 – 2007: 静岡県立大学, 薬学部, 助教授 1998 – 2001: 静岡県立大学, 薬学部, 講師 … More 1994 – 1995: 関西医科大学, 医学部, 講師 1990: Kansai Medical University, Department of Medical Chemistry Instructor (from Apri, 医学部, 講師 1989: Kansai Medical, University, Department of Medical, Chemistry, Instructor, 医化学教室, 講師 1988: 関西医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy / 代謝生物化学 Except Principal Investigator General medical chemistry / Medical pharmacy / Digestive surgery / Biological pharmacy / Biological pharmacy / Laboratory medicine
Keywords	Principal Investigator 核内受容体 / UGT1A1 / 細胞周期 / CAR / グルクロン酸抱合酵素 / platelet-activating factor / PAF / 薬物代謝酵素 / 転写調節 / scintillation proximity radioimmunoassay … More / gastric PAF / arachidonic acid release / platelet activation / ionophore A23187 / phospholipase A_2 inhibitory protein / phospholipase A_2 / PAFアセチルハイドロラーゼ / 血小板活性化因子(platelet-activating factor,PAF) / ホスホリパーゼA_2阻害因子 / ホスホリパーゼA_2 / シンチレ-ション・プロキシミティ-・ラジオイムノアッセイ(SPRIA) / GC@MS / シンチレ-ション・プロキシミティ・ラジオノムノアッセイ(SPRIA) / 胃内在性PAF / 血小板活性化因子 / アラキドン酸遊離 / 血小板活性化 / イオノホアA23187 / ホスホリパ-ゼA_2阻害タンパク質 / ホスホリパ-ゼA_2 / Growth factor / Transcriptional cofactor / Drug-metabolizing enzyme / Cell cycle / Nuclear receptor / CYP2B6 / コファクター / A1 / グルクロン酸抱合酵素UGT / constitutive androstane receptor(CAR) / 増殖因子 / 転写コファクター / flavonoids / nuclear receptor / single nucleotide polymorphism(SNP) / bilirubin / hyperbilirubinemia / Gilbert's syndrome / bilirubin LIDP-glucuronosyltransferase(UGT1A1) / プロモーター遺伝子 / フラボノイド / SNP / 遺伝子変異 / ビリルビン / 高ビリルビン血症 / 体質性黄疸 / Calcium blocker / Protein kinase inhibitor / phosphatase inhibitor / disaggregation / P-selectin / Platelet / PAFアセチルヒドロラーゼ / 接直因子 / 血小板活性化因子(PAF) / カルシウム拮抗剤 / リン酸化酵素阻害剤 / ホスファターゼ阻害剤 / 脱凝集 / P-セレクチン / 血小板 / 血小板活性化因子(PDF) / コンディショナルノックアウトマウス / β3アドレナリン受容体 / PAF受容体ノックアウトマウス / ＵＣＰ１ / UCP1クレマウス / UCP1 / 褐色脂肪細胞 / 肥満 / PAF受容体フロックスマウス / PAF受容体欠損マウス / PAF受容体 / 肝薬物代謝酵素 / 細胞周期制御因子 / UGTA 1 / 翻訳後修飾 / アセチル化 / リン酸化 / PXR / CDK2 / シグナル伝達 / サイクリン依存性キナーゼ / チェックポイント / Elk / 血清飢餓ストレス … More Except Principal Investigator PAF / 血小板活性化因子 / Y27632 / Y24180 / cAMP / 卵巣 / mRNA / シグナル伝達 / 核内受容体 / 転写調節 / Ovary / Heart muscle / Stomach / Rat / PGF<@22alpha@>2 / Vinyl PAF / Endogenous PAF inhibitors / 水浸拘束 / ビニール型PAF / 炎症性胸水 / 正常心組織 / 正常胃組織 / オ-タコイド / ケミカル・メジィエ-タ- / ビニ-ル型PAF / アシル型PAF / エストラジオ-ル / 卵巣摘出 / 子宮 / PGE_2 / PGF_2α / 心筋 / 胃 / ラット / PGF_<2α> / ビニ-ルPAF / 内在性PAFインヒビタ- / Clinical medicine / Bloloey / Stress / Surgery / 術後合併症 / 遺伝子多型 / 肝不全 / 肝切除 / 臨床 / 生態学 / ストレス / 外科 / cell signalling / Platelet disaggregation / Guanylate cyclase / PAF receptor / Platelet activating factor (PAF) / Platelet / Rho kinase阻害剤 / cGMP / 脱凝集 / 血小板脱凝集反応 / 細胞内情報伝達 / PAF脱凝集反応 / グアニルシクラーゼ / PAF受容体 / 血小板活性化因子(PAF) / 血小板 / oxidized phospholipid / arteriosclerosis obliterans / renal failure / genetic disposition / PAF acetylhydrolase / PAFアセチルヒドロラーゼ / PAF・アセチルヒドロラーゼ / 酸化脂質 / 閉塞性動脈硬化症 / 腎不全 / 遺伝素因 / PAFアセチルヒドラローゼ / in situ hybridization / corpus luteum / progesterone / gonadotropin / mouse / prostaglandin F_<2alpha> / CHO細胞 / 黄体 / Gq / PGF合成酵素 / 遺伝子 / ゴプドトロピン / 受容体 / 黄体機能 / プロスタグランジンF_<2α> / 卵巣黄体 / in situ ハイブリダイゼーション / プロゲステロン / CAMP / ゴナドトロピン / マウス / プロスタグランジン F_<2α> / シグナル伝逹 / CDK 2 / 発現制御 / 肝薬物代謝酵素 / 細胞周期 / CDK2 / 薬物代謝酵素 / サイクリン依存性キナーゼ / 糖毒性 / 転写調節因子 / 解毒酵素 / 溶血性尿毒症 / 腎障害 / アクアポリン2 / 水チャンネル / 病原性大腸菌 / ベロ毒素 / GABA / ストリキニ-ネ / 一酸化窒素(NO) / NMDA / グルタミン酸 / 痛覚過敏 / プロスタグランジン / アロディニア Less

Development of in vitro and in vivo assay systems to elucidate molecular mechanism suppressing obesityPrincipal Investigator
- Principal Investigator
  
  SUGATANI JUNKO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Regulation mechanism of expression of drug-metabolizing enzymes,UGT1A1 and CYP3A4,at cell-cycle check-pointPrincipal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Cyclin-dependent kinase 2 down-regulates expression of drug-metabolizing enzymes UGT1A1 and CYP3A4 through phosphorylation of nuclear receptor PXR
- Principal Investigator
  
  MIWA Masao
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
Expression of nuclear receptor CAR during G1 in human cells and its role in cell proliferationPrincipal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Mechanism of carbohydrate toxicity induction and its association with transcription factors involved in expression of xenobiotics-metabolizing enzymes
- Principal Investigator
  
  MIWA Masao
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Shizuoka
Relationship between the Platelet Activating Factor Acetylhydaulase Gene Polymorphism, Enzymatic Activity and Postoverative Clinical Course afher Liver Surgery
- Principal Investigator
  
  SAKAGUCHI Takanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Hamamatsu University School of Medicine
Induction of CAR and the nuclear localization are promoted in HepG2 hepatoma cells arrested at G_1 phase of cell cycle : Association with gene expression of UGT1A1 and Gadd45βPrincipal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Guanylate cyclase-cyclic GMP signaling pathway in platelet disaggregation associated with dissociation of PAF-receptor complex
- Principal Investigator
  
  MIWA Masao
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Study on defect in human UGTIAI gene promoter associated with hyperbilirubinemia and mechanism of the UGTIAI in ductionPrincipal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
病原性大腸菌毒素Stxによる腎水チャンネル(アクアポリン)障害検査法の開発
- Principal Investigator
  
  MIWA Masao
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory medicine
- Research Institution
  University of Shizuoka
Identification of major plasma PAF acetylhydrolase and study on its gene mutation as a risk factor in allergic diseases.
- Principal Investigator
  
  MIWA Masao
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Study on mechanism of newly found reverse signaling system in plateletsPrincipal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
脊髄におけるシナプス可塑性モデル、アロディニアの作用機構の解明
- Principal Investigator
  
  ITO Seiji
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kansai Medical University
Elucidation of physiological roles of prostaglandin F_<2alpha> and its regulatory mechanism in the reproductive system
- Principal Investigator
  
  ITO Seiji
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kansai Medical University
PAF in Normal Rat Tissues and its Endogenous Inhibitors
- Principal Investigator
  
  SAITO Kunihiko
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kansai Medical University
Study on mechanism of phospholipae A_2 activation.Principal Investigator
- Principal Investigator
  
  SUGATANI Junko
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  代謝生物化学
- Research Institution
  Kansai Medical University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Transcriptional regulation of human bilirubin : UDP-glucuronosyltransferase UGT1A1 gene and implication of defects in the UGT1A1 gene promoter in "Bilirubin : Chemistry, Regulation and Disorder" (Jakub F.Novotny and Florian Sedlacek eds)2012
- Author(s)
  J.Sugatani, M.Miwa
- Total Pages
  27
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-21590170
[Book] In: Bilirubin: Chemistry, Regulation and Disorder, Transcriptional regulation of human bilirubin: UDP-glucuronosyltransferase UGT1A1 gene and implication of defects in the UGT1A1 gene promoter2012
- Author(s)
  Junko Sugatani
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-22590068
[Book] Transcriptional regulation of human bilirubin : UDP-glucuronosyltransferase UGT1A1 gene and implication of defects in the UGT1A1 gene promoter in "Bilirubin : Chemistry, Regulation and Disorder" (Jakub F.Novotny and Florian Sedlacek eds)2012
- Author(s)
  J.Sugatani, M.Miwa
- Total Pages
  27
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-22590068
[Book] Transcriptional regulation of human bilirubin: UDP-glucuronosyl transferase UGT1A1gene and implication of defects in the UGT1A1gene promoter in "Bilirubin: Chemistry, Regulation and Disorder" (Jakub F. Novotny and Florian Sedlacek eds)2011
- Author(s)
  Junko Sugatani and Masao Miwa
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-22590068
[Book] Transcriptional regulation of human bilirubin : UDP-glucuronosyltransferase UGT1A1 gene and implication of defects in the UGT1A1 gene promoter in "Bilirubin : Chemistry, Regulation and Disorder"2011
- Author(s)
  Junko Sugatani and Masao Miwa
- Publisher
  NOVA Science Publishers
- Data Source
  KAKENHI-PROJECT-21590170
[Book] 酵素ハンドブック(第3版)2008
- Author(s)
  菅谷純子, 三輪匡男
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-19590151
[Book] 酵素ハンドブック(第3版)2008
- Author(s)
  菅谷純子, 三輪匡男
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-19590070
[Book] 加水分解酵素3.1.4.39-3.1.4.51、4.6.1.14「酵素ハンドブック(第3版)」(八木達彦、福井俊郎、一島英治、鏡山博行、虎谷哲夫編集)2008
- Author(s)
  菅谷純子,三輪匡男
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-19590070
[Book] 加水分解酵素3.1.4.39-3.1.4.51、4.6.1.14「酵素ハンドブック(第3版)」(八木達彦、福井俊郎、一島英治、鏡山博行、虎谷哲夫編集)2008
- Author(s)
  菅谷純子, 三輪匡男
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-19590151
[Book] 茶の効能と応用開発 Health beneficial functions and development of tea goods - 血小板凝集抑制.2006
- Author(s)
  菅谷純子, 三輪匡男
- Total Pages
  9
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Book] 茶の効能と応用開発Health beneficial functions and development of tea goods(監修:伊勢村護)2006
- Author(s)
  菅谷純子他
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15590063
[Book] 茶の効能と応用開発 Health beneficial functions and development of tea goods-血小板凝集抑制2006
- Author(s)
  菅谷純子, 三輪匡男
- Total Pages
  9
- Publisher
  シーエムシー出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Book] 茶の効能と応用開発Health beneficial functions and development of tea goods2006
- Author(s)
  菅谷純子他
- Publisher
  シーエムシー出版(監修:伊勢村護)
- Data Source
  KAKENHI-PROJECT-16590056
[Book] Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR. In "Conjugation Enzymes".2005
- Author(s)
  Junko Sugatani, et al.
- Total Pages
  13
- Publisher
  Elsevier Inc.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Book] In "Conjugation Enzymes".(H.Sies, and L.Packer, eds.) Methods in Enzymology.2005
- Author(s)
  Junko Sugatani et al.
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-16590056
[Book] In "Conjugation Enzymes".(H.Sies, and L.Packer, eds.) Methods in Enzymology.2005
- Author(s)
  Junko Sugatani et al.
- Publisher
  Elsevier Inc.
- Data Source
  KAKENHI-PROJECT-15590063
[Book] Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR. In "Conjugation Enzymes".2005
- Author(s)
  Junko Sugatani, et al.
- Total Pages
  13
- Publisher
  Elsevier Inc.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Threonine-408 Regulates the Stability of the Human Pregnane X Receptor Through its Phosphorylation and the CHIP/Chaperone- Autophagy Pathway.2016
- Author(s)
  Sugatani J, Noguchi Y, Hattori Y, Yamaguchi M, Yamazaki Y, Ikari A
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 44 Issue: 1 Pages: 137-150
- DOI
  10.1124/dmd.115.066308
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670032
[Journal Article] A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development of obesity-induced chronic inflammation.2015
- Author(s)
  Yamaguchi, M., Matsui, M., Higa, R., Yamazaki, Y., Ikari, A., Miyake, M., Miwa, M., Ishii, S., Sugatani, J., and Shimizu, T.
- Journal Title
  
  Biochem. Pharmacol.
  
  Volume: 93 Issue: 4 Pages: 482-495
- DOI
  10.1016/j.bcp.2014.12.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-25116703, KAKENHI-PROJECT-26670032, KAKENHI-PROJECT-26860041, KAKENHI-PROJECT-24229003
[Journal Article] Involvement of a Cyclic Adenosine Monophosphate-Dependent Signal in the Diet-Induced Canalicular Trafficking of Adenosine Triphosphate-Binding Cassette Transporter g5/g8.2015
- Author(s)
  Yamazaki, Y., Yasui, K., Hashizume, T., Suto, A., Mori, A., Murata, Y., Yamaguchi, Y., Ikari, A., Sugatani, J.
- Journal Title
  
  Hepatology
  
  Volume: 62 Issue: 4 Pages: 1215-1226
- DOI
  10.1002/hep.27914
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25504008, KAKENHI-PROJECT-26670032
[Journal Article] Hyperosmolarity-Induced Down-Regulation of Claudin-2 Mediated by Decrease in PKCβ-Dependent GATA-2 in MDCK Cells.2015
- Author(s)
  Ikari A, Fujii N, Hahakabe S, Hayashi H, Yamaguchi M, Yamazaki Y, Endo S, Matsunaga T, Sugatani J
- Journal Title
  
  J Cell Physiol
  
  Volume: 230 Issue: 11 Pages: 2776-2787
- DOI
  10.1002/jcp.25004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670032
[Journal Article] Threonine-290 regulates nuclear translocation of the human pregnane X receptor through its phosphorylation/dephosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1.2014
- Author(s)
  Sugatani J, Hattori Y, Noguchi Y, Yamaguchi M, Yamazaki Y, Ikari A
- Journal Title
  
  Drug Metab. Dispos.
  
  Volume: 42 Issue: 10 Pages: 1708-1718
- DOI
  10.1124/dmd.114.059139
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670032
[Journal Article] Nuclear distribution of claudin-2 increases cell proliferation in human lung adenocarcinoma cells.2014
- Author(s)
  kari A, Watanabe R, Sato T, Taga S, Shimobaba S, Yamaguchi M, Yamazaki Y, Endo S, Matsunaga T, Sugatani J
- Journal Title
  
  Biochim. Biophys. Acta.
  
  Volume: 1843 Issue: 9 Pages: 2079-2088
- DOI
  10.1016/j.bbamcr.2014.05.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26670032
[Journal Article] Antiobese function of platelet-activating factor : increased adiposity in platelet-activating factor receptor-deficient mice with age2014
- Author(s)
  Sugatani, J., Sadamitsu, S., Yamaguchi, M., Yamazaki, Y., Higa, R., Hattori, Y., Uchida, T., Ikari, A., Sugiyama, W., Watanabe, T., Ishii, S., Miwa, M., and Shimizu, T
- Journal Title
  
  FASEB J
  
  Volume: 28 Issue: 1 Pages: 440-452
- DOI
  10.1096/fj.13-233262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390061, KAKENHI-PROJECT-24229003, KAKENHI-PUBLICLY-25116703, KAKENHI-PROJECT-26670032, KAKENHI-PROJECT-26860041
[Journal Article] Tight junctional localization of claudin-16 is regulated by syntaxin 8 in renal tubular epithelial cells2014
- Author(s)
  Akira Ikari, Chie Tonegawa, Ayumi Sanada, Toru Kimura, Hideki Sakai, Hisayoshi Hayashi, Hajime Hasegawa, Masahiko Yamaguchi, Yasuhiro Yamazaki, Satoshi Endo, Toshiyuki Matsunaga, Junko Sugatani
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 19 Pages: 13112-13123
- DOI
  10.1074/jbc.m113.541193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590263, KAKENHI-PROJECT-24659095, KAKENHI-PROJECT-25293047, KAKENHI-PROJECT-26670032
[Journal Article] Function, Genetic Polymorphism, and Transcriptional Regulation of Human UDP-glucuronosyltransferase (UGT) 1A12013
- Author(s)
  Sugatani J
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 28 Issue: 2 Pages: 83-92
- DOI
  10.2133/dmpk.DMPK-12-RV-096
- NAID
  130004933533
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590068
[Journal Article] Regulation of pregnane X receptor (PXR) function and UGT1A1 gene expression by posttranslational modification of PXR protein.2012
- Author(s)
  Sugatani J, Uchida T, Kurosawa M, Yamaguchi M, Yamazaki Y, Ikari A, Miwa M
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 40(10) Issue: 10 Pages: 2031-2040
- DOI
  10.1124/dmd.112.046748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590068, KAKENHI-PROJECT-23590263
[Journal Article] Magsium deficiency suppresses cell cycle progression mediated by increase in transcriptional activity of p21Cip1 and p27Kip1 in renal epithelial NRK-52E cells2012
- Author(s)
  Ikari A, Atomi K, Takiguchi A, Yamazaki Y, Hayashi H, Hirakawa J, Sugatani J
- Journal Title
  
  J. Cell. Biochem
  
  Volume: 112 Issue: 12 Pages: 3563-3572
- DOI
  10.1002/jcb.23284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Effects of dietary inulin, statin, and their co-treatment on hyperlipidemia, hepatic steatosis and changes in drug-metabolizing enzymes in rats fed a high-fat and high-sucrose diet2012
- Author(s)
  Sugatani J, Sadamitsu S, Wada T, Yamazaki Y, Ikari A, Miwa M
- Journal Title
  
  Nutr. Metab
  
  Volume: 9 Issue: 1 Pages: 23-46
- DOI
  10.1186/1743-7075-9-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170, KAKENHI-PROJECT-22590068
[Journal Article] Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells2011
- Author(s)
  Ikari A, Sanada A, Sawada H, Okude C, Tonegawa C, Sugatani J
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1808 Pages: 1502-1508
- URL
  http://dx.doi.org/10.1016/j.bbamem2010.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Claudin-2 knockdown decreases matrix metalloproteinase-9 activity and cell migration via suppression of nuclear Sp1 in A549 cells2011
- Author(s)
  Ikari A, Atomi K, Kinjo K, Sasaki Y, Sugatani J
- Journal Title
  
  Life Sci
  
  Volume: 88 Pages: 628-633
- URL
  http://dx.doi.org/10.1016/j.lfs.2011.02.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Decrease in claudin-2 expression enhances cell migration in renal epithelial Madin-Darby canine kidney cells2011
- Author(s)
  Ikari A, Takiguchi A, Atomi K, Sato T, Sugatani J
- Journal Title
  
  J. Cell. Physiol
  
  Volume: 226 Issue: 6 Pages: 1471-1478
- DOI
  10.1002/jcp.22386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Epidermal growth factor increases clathrin-dependent endocytosis and degradation of claudin-2 protein in MDCK II cells2011
- Author(s)
  Ikari A, Takiguchi A, Atomi K, Sugatani J
- Journal Title
  
  J. Cell. Physiol
  
  Volume: 226 Issue: 9 Pages: 2448-2456
- DOI
  10.1002/jcp.22590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Diet-induced lipid accumlation in liver enhances ATP-biding cassette transporter g5/g8 expression in bile canaliculi. Drug Metab2011
- Author(s)
  Yamazaki Y, Hashizume T, Morioka H, Sadamitsu S, Ikari A, Miwa M, Sugatani J
- Journal Title
  
  Pharmacokinet
  
  Volume: 208 Pages: 442-450
- URL
  http://www.jstage.jst.go.jp/article/dmpk/26/5/26_442/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Up-regulation of TRPM6 transcriptional activity by AP-1 in renal epithelial cells2010
- Author(s)
  Ikari A, Sanada A, Okude C, Sawada H, Yamazaki Y, Sugatani J, Miwa M
- Journal Title
  
  J Cell Physiol
  
  Volume: 222 Issue: 3 Pages: 481-487
- DOI
  10.1002/jcp.21988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity : Cell-cycle dependent expression.2010
- Author(s)
  J.Sugatani, et al.
- Journal Title
  
  Drug Metab.Dispos
  
  Volume: 38(1) Pages: 177-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590068
[Journal Article] Extracellular Mg2+regulates the tight junctional localization of claudin-16 mediated by ERK-dependent phosphorylation2010
- Author(s)
  Ikari A, Kinjo K, Atomi K, Sasaki Y, Yamazaki Y, Sugatani J
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1798 Issue: 3 Pages: 415-421
- DOI
  10.1016/j.bbamem.2009.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats.2010
- Author(s)
  J.Sugatani, et al.
- Journal Title
  
  Drug Melab.Dispos.
  
  Volume: 38(10) Pages: 1655-1664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Nutritional status affects fluvastatinnduced hepatotoxicity and myopathy in rats2010
- Author(s)
  Sugatani J, Sadamitsu S, Kurosawa M, Ikushiro S, Sakaki T, Ikari A, Miwa M
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 38 Issue: 10 Pages: 1655-1664
- DOI
  10.1124/dmd.110.034090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170, KAKENHI-PROJECT-22590068
[Journal Article] Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 2 activity : Cell-cycle dependent expression2010
- Author(s)
  J.Sugatani, et al.
- Journal Title
  
  Drug Metab.Dispos 38(1)
  
  Pages: 177-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of cyclin-dependent kinase 22010
- Author(s)
  Sugatani J, Osabe M, Kurosawa M, Kitamura N, Ikari A, Miwa M
- Journal Title
  
  Drug Metab. Dispos
  
  Volume: 38 Issue: 1 Pages: 177-186
- DOI
  10.1124/dmd.109.029785
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170, KAKENHI-PROJECT-22590068
[Journal Article] Magnesium deprivation inhibits a MEK-ERK cascade and cell proliferation in renal epithelial Madin-Darby canine kidney cells2010
- Author(s)
  Ikari A, Atomi K, Kinjo K, Sasaki Y, Sugatani J
- Journal Title
  
  Life Sci
  
  Volume: 86 Pages: 766-773
- URL
  http://dx.doi.org/10.1016/j.lfs.2010.03.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats.2010
- Author(s)
  J.Sugatani, et al.
- Journal Title
  
  Drug Metab.Dispos.
  
  Volume: 38(10) Pages: 1655-1664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590068
[Journal Article] Up-regulation of CAR expression through E1k-1 in HepG2 and SW480 cells by serum starvation stress2009
- Author(s)
  M. Osabe, J. Sugatani, A. Takemura, M. Kurosawa, Y. Yamazaki, A. Ikari, M. Miwa
- Journal Title
  
  FEBS Letters 583(5)
  
  Pages: 885-889
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress2009
- Author(s)
  Makoto Osabe, Junko Sugatani, Akiko Takemura, Masatoshi Kurosawa, Yasuhiro Yamazaki, Akira Ikari, Masao Miwa
- Journal Title
  
  FEBS Letters 583(5)[IF 3.263]
  
  Pages: 885-889
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress2009
- Author(s)
  M. Osabe, J. Sugatani, A. Takemura, M. Kurosawa, Y. Yamazaki, A. Ikari, M. Miwa
- Journal Title
  
  FEBS Letters 583(5)[IF 3.263]
  
  Pages: 885-889
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Epidermal growth factor increases claudin-4 expression mediated by Sp1 elevation in MDCK cells. Biochem. Biophys2009
- Author(s)
  Ikari A, Atomi K, Takiguchi A, Yamazaki Y, Miwa M, Sugatani J
- Journal Title
  
  Res. Commun
  
  Volume: 384 Pages: 306-310
- URL
  http://dx.doi.org/10.1016/j.bbrc.2009.04.120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress2009
- Author(s)
  Osabe M, Sugatani J, Takemura A, Kurosawa M, Yamazaki Y, Ikari A, Miwa M
- Journal Title
  
  FEBS Lett
  
  Volume: 583 Pages: 885-889
- URL
  http://dx.doi.org/10.1016/j.febslet.2009.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590170
[Journal Article] PPP1R16A, the membrane subunit of protein phosphatase 1b, signals nuclear translocation of the nuclear receptor CAR.2008
- Author(s)
  T. Sueyoshi, R. Moore, J. Sugatani, Y. Matsumura, M. Negishi
- Journal Title
  
  Mol. Pharmacol. 73(4)
  
  Pages: 1113-1121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs : implication of defects in the UGT1A1 gene promoter2008
- Author(s)
  J. Sugatani, K. Mizushima, M. Osabe, K. Yamakawa, S. Kakizaki, H. Takagi, M. Mori, A. Ikari, M. Miwa
- Journal Title
  
  Naunyn Schmiedebergs Arch. Pharmacol 377(4-6)[IF 2.779]
  
  Pages: 597-605
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Constitutive androstane receptor and peroxisome proliferator-activated receptor a are activated in liver of male rats fed ahigh-fat and high-sucrose diet and the hepatic expression of UGT1A1 and UGT1A6 is enhanced.2008
- Author(s)
  M. Osabe, J. Sugatani, T. Fukuyama, S. Ikushiro, A. Ikari, M. Miwa.
- Journal Title
  
  Drug Metab. Dispos. 36
  
  Pages: 294-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Constitutive androstane receptor and peroxisome proliferator-activated receptor a are activated in liver of male rats fed a high-fat and high-sucrose diet and the hepatic expression of UGT1A1 and UGT1A6 is enhanced2008
- Author(s)
  M. Osabe, J. Sugatani, T. Fukuyama, S. Ikushiro, A. Ikari, M. Miwa
- Journal Title
  
  Drug Metab. Dispos 36(2)[IF 3.638]
  
  Pages: 294-302
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Surface localization of the nuclear receptor CAR in influenza A virus-infected cells2008
- Author(s)
  T. Takahashi, Y. Moriyama, A. Ikari, J. Sugatani T. Suzuki, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun 368(3)[IF 2.855]
  
  Pages: 550-555
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] PPP1R16A, the membrane subunit of protein phosphatase1b, signals nuclear translocation of the nuclear receptor CAR2008
- Author(s)
  T. Sueyoshi, R. Moore, J. Sugatani Y. Matsumura, M. Negishi
- Journal Title
  
  Mol. Pharmacol 73(4)[IF 4.469]
  
  Pages: 1113-1121
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal promoter motifs : implication of defects in the UGT1A1 gene promoter2008
- Author(s)
  J. Sugatani, K. Mizushima, M. Osabe, K. Yamakawa, S. Kakizaki, H. Takagi, M. Mori, A. Ikari, M. Miwa
- Journal Title
  
  Naunyn Schmiedebergs Arch. Pharmacol 377(4-6)[IF 2.779]
  
  Pages: 597-605
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation2008
- Author(s)
  M. Osabe, J. Sugatani, A. Takemura, Y. Yamazaki, A. Ikari, N. Kitamura, M. Negishi, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun 369(4)[IF 2.855]
  
  Pages: 1027-1033
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Surface localization of the nuclear receptor CAR in influenza A virus-infected cells2008
- Author(s)
  T. Takahashi, Y. Moriyama, A. Ikari, J. Sugatani T. Suzuki, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun 368(3)[IF 2.855]
  
  Pages: 550-555
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Activation of a polyvalent cation-sensing receptor decreases magnesium transport via claudin-162008
- Author(s)
  A. Ikari, C. Okude, H. Sawada, Y. Sasaki, Y. Yamazaki, J. Sugatani, M. Degawa, M. Miwa
- Journal Title
  
  Biochim. Biophys. Acta 1778(1)[IF 3.587]
  
  Pages: 283-290
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] TRPM6 expression and cell proliferation are up-regulated by phosphorylation of ERK1/2 in renal epithelial cells2008
- Author(s)
  A. Ikari, C. Okude, H. Sawada, Y. Yamazaki, J. Sugatani, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun 369(4)[IF 2.855]
  
  Pages: 1129-1133
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Constitutive androstane receptor and peroxisome proliferator-activated receptor a are activated in liver of male rats fed a high-fat and high-sucrose diet and the hepatic expression of UGT1A1 and UGT1A6 is enhanced2008
- Author(s)
  M. Osabe, J. Sugatani, T. Fukuyama, S. Ikushiro, A. Ikari, M. Miwa
- Journal Title
  
  Drug Metab. Dispos 36(2)[IF 3.638]
  
  Pages: 294-302
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation2008
- Author(s)
  M. Osabe, J. Sugatani, A. Takemura, Y. Yamazaki, A. Ikari, N. Kitamura, M. Negishi, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun 369(4)[IF 2.855]
  
  Pages: 1027-1033
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Claudin-16 is directly phosphorylated by protein kinase a independently of a vasodilator-stimulated phosphoprotein-mmediated pathway2008
- Author(s)
  A. Ikari, M. Ito, C. Okude, H. Sawada, H. Harada, M. Degawa, H. Sakai, T. Takahashi, J. Sugatani, M. Miwa
- Journal Title
  
  J. Cell Physiol 214(1)[IF3.638]
  
  Pages: 221-229
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] PPP1R16A, the membrane subunit of protein phosphatase 1b, signals nuclear translocation of the nuclear receptor CAR2008
- Author(s)
  T. Sueyoshi, R. Moore, J. Sugatani Y. Matsumura, M. Negishi
- Journal Title
  
  Mol. Pharmacol 73(4)[IF 4.469]
  
  Pages: 1113-1121
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Comparison of enzymatically synthesized inulin, resistant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high sucrose (cafeteria) diet2008
- Author(s)
  J. Sugatani, M. Osabe, T. Wada, K. Yamakawa, Y. Yamazaki, T. Takahashi, A. Ikari, M. Miwa
- Journal Title
  
  Eur. J. Nutr 47(4)[IF2.356]
  
  Pages: 192-200
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Expression of CAR in SW480 and HepG2 cells during G1 is associated with cell proliferation.2008
- Author(s)
  M. Osabe, J. Sugatani, A. Takemura, Y. Yamazaki, A. Ikari, N. Kitamura, M. Negishi, M. Miwa
- Journal Title
  
  Biochem. Biophys. Res. Commun. 369(4)
  
  Pages: 1027-1033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590070
[Journal Article] Downregulation of TRPM6-mediated magnesium influx by cyclosporine A2008
- Author(s)
  A, Ikari, C. Okude, H. Sawada, T. Takahashi, J. Sugatani, M. Miwa
- Journal Title
  
  Naunyn Schmiedebergs Arch. Pharmacol 377(4-6)[IF 2.779]
  
  Pages: 333-343
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Comparison of enzymatically synthesized inulin, resisitant maltodextrin and clofibrate effects on biomarkers of metabolic disease in rats fed a high-fat and high sucrose (cafeteria) diet.2008
- Author(s)
  J. Sugatani, M. Osabe, T. Wada, K. Yamakawa, Y. Yamazaki, T. Takahashi, A. Ikari, M. Miwa
- Journal Title
  
  Eurp. J. Nutr. 47
  
  Pages: 192-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590151
[Journal Article] Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet.2006
- Author(s)
  Kouichi Yoshinari, Shunsuke Takagi, Teruyasu Yoshimasa, Junko Sugatani, Masao Miwa
- Journal Title
  
  Pharmaceut. Res. DOI : 10. 1007/s 11095-006-
  
  Pages: 71-76
- NAID
  130004639309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Hepatic CYP3A expression is attenuated in obese mice fed a high-fat diet.2006
- Author(s)
  Kouichi Yoshinari, Shunsuke Takagi, Teruyasu Yoshimasa, Junko Sugatani, Masao Miwa
- Journal Title
  
  Pharmaceut.Res. DOI : 10. 1007/sl 1095-006-0071-6
- NAID
  130004639309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Induction of detoxifying enzymes in rodent white adipose tissue by aryl hydrocarbon receptor agonists and antioxidants.2006
- Author(s)
  Kouichi Yoshinari, Nao Okino, Takeshi Sato, Junko Sugatani, Masao Miwa
- Journal Title
  
  Drug Metab. Dispos. DOI : 10.1124/dmd
  
  Volume: 34 Issue: 7 Pages: 1081-1089
- DOI
  10.1124/dmd.105.007286
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063, KAKENHI-PROJECT-16590056
[Journal Article] Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR. In "Conjugation Enzymes".2005
- Author(s)
  J.Sugatani, T.Sueyoshi, M.Negishi, M.Miwa
- Journal Title
  
  Methods in Enzymology, Elsevier Inc. (H.Sies, and L.Packer, eds.)
  
  Pages: 92-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharlnacol. 67(3)
  
  Pages: 845-855
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani, Shinichi Nishitani, Kasumi Yamakawa, Kouichi Yoshinari, Tatsuya Sueyoshi, Masahiko Negishi, Masao Miwa
- Journal Title
  
  Mol.Pharmacol. 67(3)
  
  Pages: 845-855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Physico-chemical characterization and biological effects of inulin enzymatically synthesized from sucrose.2005
- Author(s)
  Tadashi Wada, Junko Sugatani, Etsuko Terada, Masao Ohguchi, Masao Miwa
- Journal Title
  
  J.Agric.Food.Chem. 53
  
  Pages: 1246-1253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Regulation of the human UGT1A1 gene by nuclear receptors CAR, PXR and GR. In "Conjugation Enzymes".2005
- Author(s)
  J.Sugatani, T.Sueyoshi, M.Negishi, M.Miwa
- Journal Title
  
  Methods in Enzymology (H.Sies, L.Packer, eds.) Elsevier Inc
  
  Pages: 92-104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani, Shinichi Nishitani, Kasurni Yamakawa, Kouichi Yoshinari, Tatsuya Sueyoshi, Masahiko Negishi, Masao Miwa
- Journal Title
  
  Mol.Pharmacol. 67(3)
  
  Pages: 845-855
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] A polymorphism in plasma platelet-activating factor acetylhydrolase is involved in resistance to immunoglobulin treatment in Kawasaki disease.2005
- Author(s)
  Takaomi Minami, Hiroyuki Suzuki, Takashi Takeuchi, Shigeru Uemura, Junko Sugatani, Norishige Yoshikawa
- Journal Title
  
  J.Pediatr. 147(1)
  
  Pages: 78-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharmacol 67(3)
  
  Pages: 845-855
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharmacol. 67・3
  
  Pages: 845-855
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] A polymorphism in plasma platelet-activating factor acetylhydrolase is involved in resistance to immunoglobulin treatment in Kawasaki disease.2005
- Author(s)
  Takaomi Minami, Hiroyuki Suzuki, Takashi Takeuchi, Shigeru Uemura, Junko Sugatani, Norishige Yoshikawa
- Journal Title
  
  J.Pediatr. 147(1)
  
  Pages: 78-83
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharmacol 67(3)
  
  Pages: 845-855
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression : Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharmacol. 67・3
  
  Pages: 845-855
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Physico-chemical characterization and biological effects of inulin enzymatically synthesized from sucrose.2005
- Author(s)
  Tadashi Wada, Junko Sugatani, Etsuko Terada, Masao Ohguchi, Masao Miwa
- Journal Title
  
  J.Agric.Food.Chem. 53
  
  Pages: 1246-1253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Transcriptional regulation of human UGT1A1 gene expression: Activated GR enhances CAR/PXR-mediated UGT1A1 regulation with GRIP1.2005
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Mol.Pharmacol. 67(3)
  
  Pages: 845-855
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Biochem.Pharmacol. 67・5
  
  Pages: 989-1000
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Tea polyphenols inhibit acetyl-CoA : 1-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF-induced platelet aggregation.2004
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Biochem.Pharmacol. 67・5
  
  Pages: 989-1000
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani, Kasumi Yamakawa, Eri Tonda, Shinichi Nishitani, Kouichi Yoshinan, Masakuni Degawa, Ikuro Abe, Hiroshi Noguchi, Masao Miwa
- Journal Title
  
  Biochem.Phalmacol. 67(5)
  
  Pages: 989-1000
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Tea polyphenols inhibit acetyl-CoA : l-alkyl-sn-glycero-3- phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF- induced platelet aggregation.2004
- Author(s)
  Junko Sugatani, Nana Fukazawa, Kenji Ujihara, Kouichi Yoshinari, Ikuo Abe, Hiroshi Noguchi, Masao Miwa
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Tea polyphenols inhibit acetyl-CoA : 1-alkyl-sn-glycero-3- phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF- induced platelet aggregation.2004
- Author(s)
  Junko Sugatani, et al.
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Tea polyphenols inhibit acetyl-CoA : 1-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF-induced platelet aggregation.2004
- Author(s)
  Junko Sugatani, Nana Fukazawa, Kenji Ujihara, Kouichi Yoshinari, Ikuo Abe, Hiroshi Noguchi, Masao Miwa
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Tea polyphenols inhibit acetyl-CoA:1-alkyl-sn-glycero-3-phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF- induced platelet aggregation.2004
- Author(s)
  Junko Sugatani et al.
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani, Kasumi Yamakawa, Eri Tonda, Shinichi Nishitani, Kouichi Yoshinari, Masakuni Degawa, Ikuro Abe, Hiroshi Noguchi, Masao Miwa
- Journal Title
  
  Biochem. Phalmacol. 67(5)
  
  Pages: 989-1000
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani, et al.
- Journal Title
  
  Biochem.Phalmacol. 67(5)
  
  Pages: 989-1000
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] Expression and Induction of Cytochromes P450 in Rat White Adipose Tissue.2004
- Author(s)
  Kouichi Yoshinari, Takeshi Sato, Nao Okino, Junko Sugatani, Masao Miwa
- Journal Title
  
  J.Phalmacol.Exp Ther. 311
  
  Pages: 147-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590063
[Journal Article] The induction of human bilirubin UDP-glucuronosyltransferase mediated through a distal enhancer module by flavonoids and xenobiotics.2004
- Author(s)
  Junko Sugatani, et al.
- Journal Title
  
  Biochem.Phalmacol. 67(5)
  
  Pages: 989-1000
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Expression and Induction of Cytochromes P450 in Rat White Adipose Tissue.2004
- Author(s)
  Kouichi Yoshinari, Takeshi Sato, Nao Okino, Junko Sugatani, Masao Miwa
- Journal Title
  
  J.Pharmacol.Exp Ther. 311
  
  Pages: 147-154
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Journal Article] Tea polyphenols inhibit acetyl-CoA:1-alkyl-sn-glycero-3- phosphocholine acetyltransferase (a key enzyme in PAF biosynthesis) and PAF- induced platelet aggregation.2004
- Author(s)
  Junko Sugatani, et al.
- Journal Title
  
  Intern.Arch.Allergy Immunol. 134
  
  Pages: 17-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590056
[Presentation] 肥満誘発マウスの慢性炎症における血小板活性化因子の機能解明2015
- Author(s)
  松井雅和、山口賢彦、須山大輔、宮武将之、山崎泰広、五十里彰、菅谷純子
- Organizer
  第79回日本生化学会中部支部例会・シンポジウム
- Place of Presentation
  松本
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] 血小板活性化因子受容体欠損で誘発された肥満マウスの慢性炎症反応とその制御機構の解析2015
- Author(s)
  松井雅和、山口賢彦、須山大輔、宮武将之、山崎泰広、五十里彰、菅谷純子
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] Threonine-408 regulates the stability of the human pregnane X receptor through its phosphorylation and the CHIP/chaperone- autophagy pathway.2015
- Author(s)
  Junko Sugatani, Yuji Noguchi, Yoshiki Hattori, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari
- Organizer
  20th North American ISSX Meeting
- Place of Presentation
  Orland, USA
- Year and Date
  2015-10-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced　obesity and PAF/PAF receptor signaling up-regulates an energy expenditure inducer in adipocytes.2015
- Author(s)
  Yamaguchi M, Matsui M, Yamazaki Y, Ikari A, Miwa M, Ishii S, Shimizu T, Sugatani J
- Organizer
  6th International Conference on PLA2 and lipid mediators
- Place of Presentation
  Tokyo
- Year and Date
  2015-02-10
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] 脂肪組織の慢性炎症化過程に関わる血小板活性化因子の機能解析2014
- Author(s)
  山口賢彦、比嘉涼子、山崎泰広、五十里彰、石井聡、三輪匡男、清水孝雄、菅谷純子
- Organizer
  第56回日本脂質生化学会
- Place of Presentation
  大阪
- Year and Date
  2014-06-07
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] 核内受容体PXRのスレオニン290のリン酸化/脱リン酸化反応が核内移行制御の中心的役割を担う2014
- Author(s)
  服部芳樹、山口賢彦、山崎泰広、五十里彰、菅谷純子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] Threonine-290 regulates nuclear translocation of the human pregnane X receptor through its phosphorylation/dephosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1.2014
- Author(s)
  Yoshiki Hattori, Yuji Nogchi, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari, and Junko Sugatani
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] 核内受容体PXRの核内移行制御の中心的役割をスレオニン290リン酸化/脱リン酸化反応が担う2014
- Author(s)
  服部芳規、山口賢彦、山崎泰広、五十里彰、菅谷純子
- Organizer
  第６０回日本薬学会東海支部大会
- Place of Presentation
  三重
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] UGT1A1遺伝子発現制御異常に起因するグルクロン酸抱合体排泄機能障害に基づく疾患について2014
- Author(s)
  菅谷純子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] Platelet-Activating Factor Receptor Deficiency Exacerbates Diet-induced Obesity and Glucose Metabolism Disorders.2014
- Author(s)
  Yamaguchi　Ｍ, Matsui　Ｍ, Yamazaki　Ｙ, Ikari A, Sugatani J
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] Regulation of PXR function by post-translational modification2012
- Author(s)
  Junko Sugatani
- Organizer
  19th International Symposium on Microsomesand Drug Oxidations (MDO) and 12th European Regional ISSX Meeting
- Place of Presentation
  Noordwijk aan Zee, the Netherlands
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation]2012
- Author(s)
  Junko Sugatani
- Organizer
  Regulation of PXR function by post-translational modification. 19th International Symposium on Microsomes and Drug Oxidations (MDO) and 12th European Regional ISSX Meeting Abstracts、p. 15、p. 147
- Place of Presentation
  Noordwijk aan Zee, the Netherlands
- Year and Date
  2012-06-20
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Regulation of PXR function and UGT1A1 gene expression by post-translational modification of PXR protein.2012
- Author(s)
  Takahiro Uchida, Yoshiki Hattori, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari, Junko Sugatani
- Organizer
  The 1stInternational Conference on Pharma-Food (ICPF 2012) Abstract, p. 118
- Place of Presentation
  Shizuoka
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 翻訳後に修飾された核内受容体PXRのUGT1A1発現におよぼす影響2012
- Author(s)
  内田貴啓、服部芳規、黒澤雅俊、山口賢彦、山崎泰広、五十里彰、菅谷純子
- Organizer
  第85回日本生化学会大会プログラム、p.147
- Place of Presentation
  福岡
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 核内受容体PXRのリガンド結合部位を介した活性化制御機構について2012
- Author(s)
  菅谷純子、内田貴啓、黒澤雅俊、山崎泰広、五十里彰、三輪匡男
- Organizer
  第132年会日本薬学会講演要旨集、p.203
- Place of Presentation
  札幌
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Cyclin-dependent kinase 2 down-regulates expression of drug-metabolizing enzymes UGT1A1 and CYP3A4 through phosphorylation of nuclear receptor PXR in S phase2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 核内受容体PXRを介したUGT1A1発現調節機構の解析2011
- Author(s)
  内田貴啓、黒澤雅俊、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第131年回日本薬学会講演要旨集3、p.173
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Cyclin-dependent kinase 2 down-regulates expression of drug-metabolizing enzymes UGT1A1 and CYP3A4 through phosphorylation of nuclear receptor PXR in S phase2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第34回日本分子生物学会年会(横浜)
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 核内受容体を介したUGT1A1遺伝子転写調節2011
- Author(s)
  菅谷純子
- Organizer
  核内受容体を介したUGT1A1遺伝子転写調節
- Place of Presentation
  大阪
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 核内受容体PXRを介したUGT1A1発現調節機構の解析2011
- Author(s)
  内田貴啓、黒澤雅俊、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第131年回日本薬学会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] サイクリン依存性キナーゼ2は核内受容体PXRを介して薬物代謝酵素CYP3A4、UGT1A1の発現を負に調節する2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第75回日本生化学会中部支部シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Cyclin-dependent kinase 2 down-regulates expression of drug-metabolizing enzymes UGT1A1 and CYP3A4 through phosphorylation of nuclear receptor PXR in S phase2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 核内受容体を介したUGT1A1遺伝子転写調節2011
- Author(s)
  菅谷純子
- Organizer
  P450とUGTの勉強会
- Place of Presentation
  大阪
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] サイクリン依存性キナーゼ2は核内受容体PXRを介して薬物代謝酵素CYP3A4、UGT1A1の発現を負に調節する2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第75回日本生化学会中部支部シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Nutritional status influences basal and drug-induced expression of drug-metabolizing enzymes and transporters and drug-adverse effects2011
- Author(s)
  Junko Sugatani
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 核内受容体を介したUGT1A1遺伝子転写調節2011
- Author(s)
  菅谷純子
- Organizer
  核内受容体を介したUGT1A1遺伝子転写調節
- Place of Presentation
  大阪
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] サイクリン依存性キナーゼ2は核内受容体PXRを介して薬物代謝酵素CYP3A42011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  UGT1A1の発現を負に調節する第75回日本生化学会中部支部シンポジウム
- Place of Presentation
  静岡
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Nutritional status influences basal and drug-induced expression of drug-metabolizing enzymes and transporters and drug-adverse effects.2011
- Author(s)
  Junko Sugatani
- Organizer
  第26回日本薬物動態学会講演要旨集p.189
- Place of Presentation
  広島
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats : Association with the suppression of hepatic organic anion transporting polypeptide 22011
- Author(s)
  Junko Sugatani, Satoshi Sadamitsu, Masatoshi Kurosawa, Akira Ikari, Masao Miwa
- Organizer
  4^<th> International conference on health and longevity sciences
- Place of Presentation
  静岡
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats : Association with the suppression of hepatic organic an ion transporting polypeptide 22011
- Author(s)
  Junko Sugatani, Satoshi Sadamitsu, Masatoshi Kurosawa, Akira Ikari, Masao Miwa
- Organizer
  4^<th> International conference on health and longevity sciences
- Place of Presentation
  静岡
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Cyclin-dependent kinase 2 down-regulates expression of drug-metabolizing enzymes UGT1A1 and CYP3A4 through phosphorylation of nuclear receptor PXR in S phase.2011
- Author(s)
  内田貴啓、黒澤雅俊、平川城太朗、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第34回日本分子生物学会年会プログラム、p.360
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] PAF受容体欠損マウスで見いだされた新規なPAF生理機能の解明2011
- Author(s)
  菅谷純子、定光慧、山崎泰広、黒澤雅俊、長澤孝真、杉山渉、五十里彰、渡辺達夫、三輪匡男、石井聡、清水孝雄
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  東京
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] PAF受容体欠損マウスで見いだされた新規なPAF生理機能の解明2011
- Author(s)
  菅谷純子、定光慧、山崎泰広、黒澤雅俊、長澤孝真、杉山渉、五十里彰、渡辺達夫、三輪匡男、石井聡、清水孝雄
- Organizer
  第53回日本脂質生化学会
- Place of Presentation
  東京
- Year and Date
  2011-05-28
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Nutritional status influences basal and drug-induced expression of drug-metabolizing enzymes and transporters and drug-adverse effects2011
- Author(s)
  Junko Sugatani
- Organizer
  第26回日本薬物動態学会
- Place of Presentation
  広島
- Year and Date
  2011-11-18
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats : Association with the suppression of hepatic organic anion transporting polypeptide 2.2010
- Author(s)
  Junko Sugatani, Satoshi Sadamitsu, Masatoshi Kurosawa, Akira Ikari, Masao Miwa
- Organizer
  3^<nd> International conference on health and longevity sciences "Integrated food-pharmaceutical science"
- Place of Presentation
  静岡県立大学
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Expression of UGT1A1 is regulated by cell signals associated with cell-cycle progression.2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Nutritional status affects fluvastatin-induced hepatotoxicity and myopathy in rats : Association with the suppression of hepatic organic anion transporting polypeptide 2.2010
- Author(s)
  Junko Sugatani, Satoshi Sadamitsu, Masatoshi Kurosawa, Akira Ikari, Masao Miwa
- Organizer
  3^<nd> International conference on health and longevity sciences "Integrated food-pharmaceutical science"
- Place of Presentation
  静岡県立大学
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Transcriptional regulation of human UDP-glucoronosyltransferase UGT1A1 gene expression and the alteration in its protein expression by intracellular factors controlling cell proliferation2010
- Author(s)
  菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] CDKシグナル伝達系を介した核内受容体CAR発現調節機序の解明2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Fluvastatin causes severer hepatic unjury and myopathy in rats fed a high-tat and high-sucrose diet than a standard diet : association with the suppression of hepatic organic anion transporting polypeptide 2.2010
- Author(s)
  定光慧、黒澤雅俊、生城真一、榊俊之、五十里彰、二輪匡男、菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞周期に依存した薬物代謝酵素の発現制御2010
- Author(s)
  黒澤雅俊, 定光慧, 山崎泰広, 五十里彰, 三輪匡男, 菅谷純子
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Expression of UGT1A1 is regulated by cell signals associated with cell-cycle progression.2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Transcriptional regulation of human UDP-glucoronosyl transferase UGT1A1 gene expression and the alteration in its protein expression by intracellular factors controlling cell proliferation.2010
- Author(s)
  菅谷純子
- Organizer
  第25回日本薬物動態学会講演要旨集p.178
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 酵素合成イヌリン添加食による脂肪肝増悪化抑制と連動した肝薬物代謝酵素発現変動の改善2010
- Author(s)
  定光慧、和田正、長澤孝真、平本洸貴、五十里彰、三輪匡男、菅谷純子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞周期に依存した薬物代謝酵素の発現抑制2010
- Author(s)
  黒澤雅俊、定光慧、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第130年回日本薬学会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Fluvastatin causes severer hepatic unjury and myopathy in rats fed a high-fat and high-sucrose diet than a standard diet : association with the suppression of hepatic organic anion transporting polypeptide 2.2010
- Author(s)
  定光慧、黒澤雅俊、生城真一、榊俊之、五十里彰、三輪匡男、菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Transcriptional regulation of human UDP-glucoronosyltransferase UGT1A1 gene expression and the alteration in its protein expression by intracellular factors controlling cell proliferation.2010
- Author(s)
  菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] CDKシグナル伝達系を介した核内受容体CAR発現調節機序の解明2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] 酵素合成イヌリン添加食による脂肪肝増悪化抑制と連動した肝薬物代謝酵素発現変動の改善2010
- Author(s)
  定光慧、和田正、長澤孝真、平本洸貴、五十里彰、三輪匡男、菅谷純子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] CDKシグナル伝達系を介した核内受容体CAR発現調節機序の解明2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] Expression of UGT1A1 is regulated by cell signals associated with cell-cycle progression2010
- Author(s)
  黒澤雅俊、内田貴啓、五十里彰、三輪匡男、菅谷純子
- Organizer
  第25回日本薬物動態学会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 酵素合成イヌリンと抗高脂血症薬併用による抗肥満作用と薬物代謝酵素発現に及ぼす影響の解析2009
- Author(s)
  定光慧, 今西正樹, 長部誠, 和田正, 山崎泰広, 五十里彰, 菅谷純子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Induction of UGT1A1 and CYP 2B6 by an antimitogenic factor in HepG 2 cells is mediated through suppression of CDK2 activity2009
- Author(s)
  Junko Sugatani, Makoto Osabe, Masatos hi Kurosawa, Yasuhiro Yamazaki, Akira Ikari
- Organizer
  2nd International conf erence on health and longevity sciences, Yaku-shoku Dogen,'Medicine and food, sharing a common origin
- Place of Presentation
  University of Shizuoka
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 血清飢餓ストレスによる核内受容体CARの発現誘導機構2009
- Author(s)
  竹村明子、黒澤雅俊、長部誠、山崎泰広、五十里彰、菅谷純子
- Organizer
  日本薬学会第129年会(講演要旨集3)
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] Induction of UGT1A1 and CYP2B6 by an antimitogenic factor in HepG2 cells is mediated through suppression of CDK2 activity2009
- Author(s)
  菅谷純子, 長部誠, 黒澤雅俊, 山崎泰広, 五十里彰
- Organizer
  2^<nd> International conference on health and longevity sciences, Yaku-shoku Dogen, 'Medicine and food, sharing a common origin
- Place of Presentation
  静岡県立大学
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞外シグナル伝達系と連携したグルクロン酸抱合酵素UGT1A1発現調節機構の解明2009
- Author(s)
  黒澤雅俊、長部誠、山崎泰広、五十里彰、菅谷純子
- Organizer
  UGT研究会2009
- Place of Presentation
  静岡
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 血清飢餓ストレスによる核内受容体CARの発現誘導機構2009
- Author(s)
  竹村明子, 黒澤雅俊, 長部誠, 山崎康広, 五十里彰, 菅谷純子
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] サイクリン依存性キナーゼ2はヒトUDP-グルクロン酸転移酵素UGT1A1発現を抑制する2009
- Author(s)
  黒澤雅俊、竹村明子、長部誠、山崎泰広、五十里彰、菅谷純子
- Organizer
  日本薬学会第129年会(講演要旨集3)
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] Cell cycle-dependent exp ression of CYP and UGT regulated by c yclin-dependent kinases in HepG2 and S W480 cells2009
- Author(s)
  Junko Sugatani
- Organizer
  16^<th> International Conference on Cytochrome P450.
- Place of Presentation
  Okinawa(Nago)
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 酵素合成イヌリンと抗高脂血症薬併用による抗肥満作用と薬物代謝酵素発現に及ぼす影響の解析2009
- Author(s)
  定光慧、今西正樹、長部誠、和田正、山崎泰広、五十里彰、菅谷純子
- Organizer
  日本薬学会第129年会(講演要旨集3)
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] CDK2シグナル伝達系を介した薬物代謝酵素CYP2B6、UGT1A1発現調節機序の解明2009
- Author(s)
  黒澤雅俊、長部誠、喜多村直美、山崎泰広、五十里彰、三輪匡男、菅谷純子
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞増殖抑制シグナル伝達系と連携したCYP2B62009
- Author(s)
  菅谷純子、長部誠、黒澤雅俊、山崎泰広、五十里彰、三輪匡男
- Organizer
  UGT1A1発現調節機構の解明第2回博多シンポジウム「内・外環境と生物応答」
- Place of Presentation
  博多
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞増殖抑制シグナル伝達系と連携したCYP2B6、UGT1A1発現調節機構の解明2009
- Author(s)
  菅谷純子, 長部誠, 黒澤雅俊, 山崎泰広, 五十里彰, 三輪匡男
- Organizer
  第2回博多シンポジウム「内・外環境と生物応答
- Place of Presentation
  九州大学
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21590170
[Presentation] 細胞周期に依存した薬物代謝酵素誘導の解析2008
- Author(s)
  竹村明子、長部誠、黒澤雅俊、山崎泰広、五十里彰、菅谷純子
- Organizer
  第54回日本薬学会東海支部総会・大会(講演要旨集)
- Place of Presentation
  名古屋
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 細胞生育環境によるUGT1A1発現変動の解析2008
- Author(s)
  菅谷純子、長部誠、竹村明子、黒澤雅俊、山崎泰広、五十里彰、三輪匡男
- Organizer
  第11回P450研究会、第3回UGT研究会合同開催
- Place of Presentation
  福岡
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] メタボリックシンドロームと薬物代謝 : 酵素合成イヌリン摂取による脂肪肝形成時に認められる肝機能障害抑制効果2008
- Author(s)
  菅谷純子
- Organizer
  第13回静岡健康・長寿学術フォーラム「元気な血管で健康な長寿を-老いは血管に始まる」、グランシップ
- Place of Presentation
  静岡
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Transcriptional regulation of UGT1A1 gene expression and its cell-cycle-dependent ecpression by nuclear receptor CAR2008
- Author(s)
  Junko Sugatani, Makoto Osabe, Akiko Takemura, Yasuhiro Yamazaki, Akira Ikari, Masao Miwa
- Organizer
  The 12th International Glucuronidation and UGT Workshop
- Place of Presentation
  Quebec, Canada
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 酵素合成法によるイヌリンの抗肥満作用機構の解析2008
- Author(s)
  菅谷純子、和田正、長部誠、鎌田修二、近江明大、石川智子、山崎泰広、五十里彰、三輪匡男
- Organizer
  日本薬学会第128年会(講演要旨集3)(59)
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 核内受容体CARの細胞周期に基づく発現制御とその機能について2008
- Author(s)
  長部誠、菅谷純子、福山知哲、竹村明子、山崎康広、五十里彰、三輪匡男
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] Comparison of enzymatically synthesized inulin, clofibrate and fluvastatin effects on biomarkers of metabolic disease and drug metabolism in rats fed standard and cafeteria diets2008
- Author(s)
  J. Sugatani, M. Osabe, S. Sadamitsu, M. Imanishi, Y. Yamazaki, A. Ikari, M. Miwa
- Organizer
  1^<st> International conference on health and longevity sciences, Yaku-shoku Dogen、'Medicine and food, sharing a common origin
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Comparison of enzymatically synthesized inulin, clofibrate and fluvastatin effects on biomarkers of metabolic disease and drug metabolism in rats fed standard and cafeteria diets2008
- Author(s)
  Junko Sugatani, Makoto Osabe, Satoshi Sadamitsu, Masaki Imanishi, Yasuhiro Yamazaki, Akira Ikari, Masao Miwa
- Organizer
  1^<st> International conference on health and longevity sciences, Yaku-shoku Dogen、'Medicine and food, sharing a common origin
- Place of Presentation
  University of Shizuoka
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] メタボリツクシンドロームと薬物代謝 : 酵素合成イヌリン摂取による脂肪肝形成時に認められる肝機能障害抑制効果2008
- Author(s)
  菅谷純子
- Organizer
  第13回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 核内受容体CARの細胞周期に基づく発現制御とその機能について2008
- Author(s)
  長部誠、菅谷純子、福山知哲、竹村明子、山崎泰広、五十里彰、三輪匡男
- Organizer
  日本薬学会第128年会(講演要旨集3)
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] ストレス刺激により誘導される核内受容体CARの発現調節機構の解析BMB20082008
- Author(s)
  菅谷純子、長部誠、竹村明子、黒澤雅俊、山崎泰広、五十里彰、三輪匡男
- Organizer
  第81回日本生化学会大会(講演要旨集)
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 高カロリー食摂取ラットにおける肝コレステロールトランスポーターAbcg5/8発現変動の解析2008
- Author(s)
  山崎泰広、長部誠、松井久美子、鎌田修二、近江明大、竹村明子、五十里彰、菅谷純子、三輪匡男
- Organizer
  日本薬学会第128年会(講演要旨集3)
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] ストレス刺激により誘導される核内受容体CARの発現調節機構の解析2008
- Author(s)
  菅谷純子, 長部誠, 竹村明子, 黒澤雅俊, 山崎泰広, 五十里彰, 三輪匡男
- Organizer
  第81回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 高脂肪高糖質食で飼育したラット肝薬物代謝酵素/トランスポーターの発現変動について2007
- Author(s)
  長部誠、菅谷純子、福山知哲、山崎泰広、高橋忠伸、五十里彰、三輪匡男
- Organizer
  第53回日本薬学会東海支部総会・大会(講演要旨集)(28)
- Place of Presentation
  名古屋
- Year and Date
  2007-07-07
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 高カロリー食の摂取により脂肪肝を形成したラット肝臓のグルクロン酸抱合酵素UGT1A1、UGT1A6の発現亢進は核内受容体CAR、PPARaの活性化に起因するBMB20072007
- Author(s)
  水嶋康介、菅谷純子、長部誠、福山知哲、山崎泰広、五十里彰、三輪匡男
- Organizer
  第80回日本生化学会大会(332)
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 高カロリー食の摂取により脂肪肝を形成したラット肝臓のグルクロン酸抱合酵素UGT1A1、UGT1A6の発現亢進は核内受容体CAR、PPARαの活性化に起因する2007
- Author(s)
  水嶋康介、菅谷純子、長部誠、福山知哲、山崎康広、五十里彰、三輪匡男
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 高栄養状態で長期に飼育したラットの肝薬物代謝酵素/トランスポーターの発現変動について2007
- Author(s)
  菅谷純子
- Organizer
  第10回P450研究会、第2回UGT研究会合同開催
- Place of Presentation
  富山
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Expression of CAR and its function associated with cell cycle. BMB20072007
- Author(s)
  Makoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Yasuhiro Yamazaki, Akira Ikari, Masao Miwa
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 脂肪肝形成モデル動物の薬物動態-アセトアミノフェングルクロン酸抱合反応の亢進2007
- Author(s)
  長部誠、菅谷純子、福山知哲、山崎康広、五十里彰、三輪匡男
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] 脂肪肝形成モデル動物の薬物動態-アセトアミノフェングルクロン酸抱合反応の亢進2007
- Author(s)
  長部誠、菅谷純子、福山知哲、山崎泰広、五十里彰、三輪匡男
- Organizer
  第1回次世代を担う若手医療薬科学シンポジウム
- Year and Date
  2007-12-15
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Dietary inulin alleviates hepatic steatosis and xenobiotics-induced liver injury in rats fed a high-fat and high-sucrose diet : Association with the suppression of hepatic cytochrome P450 and HNF4a expression2007
- Author(s)
  Makoto Osabe, Junko Sugatani, Tadashi Wada, Tadanobu Takahashi, Akira Ikari, Masao Miwa
- Organizer
  The 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects, International Receptor Symposium
- Place of Presentation
  Shizuoka, Japan
- Data Source
  KAKENHI-PROJECT-19590151
[Presentation] Transcriptional regulation of human UGT1A1 gene expression through distal and proximal reporter genes by nuclear receptors2007
- Author(s)
  Junko Sugatani, Kousuke Mizushima, Makoto Osabe, Tadanobu Takahashi, Akira Ikari, Masao Miwa
- Organizer
  The 5th International Symposium on Receptor Mechanisms, Signal Transduction and Drug Effects, International Receptor Symposium
- Place of Presentation
  Shizuoka, Japan
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] Expression of CAR and its function associated with cell cycle2007
- Author(s)
  Makoto Osabe, Junko Sugatani, Tomoaki Fukuyama, Yasuhiro Yamazaki, Akira Ikari, Masao Miwa
- Organizer
  第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] 細胞生育環境に依存した核内受容体CAR発現調節2007
- Author(s)
  長部誠、菅谷純子、福山知哲、水嶋康介、高橋忠伸、五十里彰、三輪匡男
- Organizer
  第127年回日本薬学会(講演要旨集)
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Data Source
  KAKENHI-PROJECT-19590070
[Presentation] Signal-mediated regulation of nuclear receptor PXR function.
- Author(s)
  Junko Sugatani, Yoshiki Hattori, Yuji Noguchi, Masahiko Yamaguchi, Yasuhiro Yamazaki, Akira Ikari
- Organizer
  20th International Symposium on Microsomes and Drug Oxidations
- Place of Presentation
  Stuttgart, Germany
- Year and Date
  2014-05-18 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-26670032
[Presentation] 翻訳後に修飾された核内受容体PXRのUGT1A1発現におよぼす影響
- Author(s)
  内田貴啓（菅谷純子）
- Organizer
  第85回日本生化学会大会（福岡）
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] PXR翻訳後修飾が薬物代謝酵素発現に及ぼす影響
- Author(s)
  内田貴啓（菅谷純子）
- Organizer
  第58回日本薬学会東海支部大会（静岡）
- Place of Presentation
  静岡県静岡市
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] PXR翻訳後修飾がUGT1A1発現に及ぼす影響
- Author(s)
  菅谷純子
- Organizer
  P450とUGT/SULT勉強会
- Place of Presentation
  兵庫県三田
- Data Source
  KAKENHI-PROJECT-22590068
[Presentation] Regulation of PXR function and UGT1A1 gene expression by post-translational modification of PXR protein
- Author(s)
  Takahiro Uchida (Junko Sugatani)
- Organizer
  The 1st International Conference on Pharma-Food (ICPF 2012) (Shizuoka)
- Place of Presentation
  静岡県静岡市
- Data Source
  KAKENHI-PROJECT-22590068

1. MIWA Masao (10046287)

# of Collaborated Projects: 9 results

# of Collaborated Products: 68 results
2. YOSHINARI Kouichi (60343399)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
3. ITO Seiji (80201325)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YAMAGUCHI MASAHIKO (00632639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. SAKAMOTO Kazuichi (90235169)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HAYASHI Machiko (50137072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. MAEDA Toshio (00137069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAGUCHI Takanori (70313955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAMURA Toshio (40283353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. INABA Keisuke (10397383)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. SAITO Kunihiko (80077560)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NAKAYAMA Reiko (60172483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SATOUCHI Kiyoshi (50098125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 益康夫 (40202311)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 石井聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 山崎泰広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 五十里彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SUGATANI JUNKO 菅谷 純子

SUGATANI Junko 菅谷 純子

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Development of in vitro and in vivo assay systems to elucidate molecular mechanism suppressing obesityPrincipal Investigator

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Regulation mechanism of expression of drug-metabolizing enzymes,UGT1A1 and CYP3A4,at cell-cycle check-pointPrincipal Investigator

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Expression of nuclear receptor CAR during G1 in human cells and its role in cell proliferationPrincipal Investigator

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Induction of CAR and the nuclear localization are promoted in HepG2 hepatoma cells arrested at G_1 phase of cell cycle : Association with gene expression of UGT1A1 and Gadd45βPrincipal Investigator

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Study on defect in human UGTIAI gene promoter associated with hyperbilirubinemia and mechanism of the UGTIAI in ductionPrincipal Investigator

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Study on mechanism of newly found reverse signaling system in plateletsPrincipal Investigator

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SUGATANI JUNKO 菅谷純子

SUGATANI Junko 菅谷純子