TAKAHARA Hidenari 高原英成

… Alternative Names

高原英成タカハラヒデナリ

高原秀成タカハラヒデナリ

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Researcher Number	30122063
Other IDs
External Links
Affiliation (based on the past Project Information) *help	1998 – 2013: 茨城大学, 農学部, 教授 2003: 近畿大学, 農学部, 教授 1996: 茨城大学, 農学部, 教授 1994 – 1995: 茨城大学, 農学部, 助教授 1988 – 1991: Faculty of Agriculture, Ibaraki University, Assoc. Professor, 農学部, 助教授 1986 – 1987: 茨城大学, 農学部, 助手
Review Section/Research Field	Principal Investigator 応用微生物学・応用生物化学 / 応用生物化学・栄養化学 / Applied biochemistry Except Principal Investigator 応用生物化学・栄養化学 / Dermatology / Dermatology / 植物保護
Keywords	Principal Investigator ペプチジルアルギニンデイミナーゼ / mouse / ペプチジルアルギニンデイミナ-ゼ / Padi4 / reporter gene / peptidylarginine / promoter / human / gene regulation / gene structure … More / deiminase / peptidylarginine deiminase / 蛋白質アルギニン脱イミノ酵素 / マウス子宮 / Chemical Modification of reactive center / Structure of reactive center / Peptidylarginine deiminase / ヨードアセトアミドによる活性中心システイン残基の修飾 / ヨードアセトアミドによる活性中心残基の修飾 / 活性中心の化学修飾 / 活性中心構造 / pristine / systemic lupus erythematosus / autoantibody / arthritis rheumatoides / peritoneal macrophage / monoclonal antibody / PADi4 / snRNP / 全身性エリテマトーデス / マウスPadi4遺伝子 / Pristine / 全身性エステマトーデス / 自己抗体 / 慢性関節リウマチ / 腹腔マクロファージ / モノクローナル抗体 / 蛋白質アルギニン脱イミノ / luciferase assay / silencer / reporter assay / deimunase / Peptidylarginine / reparter gene / peptidy larginine / knockout mouse / Gene Targeting / 粒子間反発力 / ノックアウトマウス / マウス / ジーンターゲティング / グリセルアルデヒド３リン酸デヒドロゲナーゼ / ニワトリ網膜 / retina / chicken / PAD / siRNA / 過剰発現 / 鳥類アデノ随伴ウイルス / 水平細胞 / 双極細胞 / 視細胞 / 網膜 / ニワトリ / タンパク質アルギニン脱イミノ酵素 / 5'-RACE / 3'-RACE / RT-PCR / 免疫細胞化学 / アイソタイプT4 / cDNAクローニング / ヒト毛細胞 / エキソンマップ / トランスグルタミナーゼ / トリコヒアリン / フィラグリン / Two-Cistron発現ベクター / 高機能キメラ酵素 / 遺伝子組換え型酵素 / 3'RACE法 / 5'RACE法 / RT-PCR法 / cDNA クローニング / ヒト正常培養表皮細胞 / ラット表皮 / pkkPADー4 / 発現ベクタ- / 大腸菌発現系 / 遺伝子組換え酵素 / cDNA / 遺伝子発現調節 / 妊娠子宮脱落膜 / 卵巣摘出マウス / 免疫組織化学 / エストロゲン … More Except Principal Investigator Peptidylarginine deiminase / HMG2 / HMG1 / MZF1 / NF-Y / Sp3 / Sp1 / PADI1 / PADI3 / gene regulation / peptidylarginine deiminase / ペプチジルアルギニンデイミナーゼ / cDNA / PAD T4 / シトルリン残基 / ヒト毛嚢 / Citrulline residue / Modification of arginine residue / HMGの修飾 / シトルリンの定量 / アルギニン残基の修飾 / human keratinocytes / 基本転写因子 / 転写制御 / TATA-box / peptidylarginine deiminas / keratinocyte / immunohistochemistry / monoclonal antibody / trichohyaline / expression plasmid / human hair cell / cDNAクローニング / Two-cistran / 大腸菌発現 / ヒト毛細管 / 免疫組織化学 / モノクローナル抗体 / トリコヒアリン / 大腸菌発現系 / ヒト毛細胞 / ペプチヅルアルギニンデイミナーゼ / CDNA cloning / Isozyme / Primary structure of protein / Protein deiminating enzyme / 蛋白質脱イミノ酸 / ペプチジルアルギニンディミナ-ゼ / ゲノムDNAクロ-ニング / cDNAクロ-ニング / アイソザイム / 蛋白質の一次構造 / 蛋白質脱イミノ酵素 / ペプチジルアルギニンデイミナ-ゼ / シトルリン残基のアルギニン残基への変換 / 蛋白質修飾酵素 / シトルリン残 / 小角散乱 / 蛍光分光分析 / トランスグルタミナーゼ / 架橋反応 / ヒト毛嚢キューティクル / X線 / 結晶化 / 脱イミノ化 / ヒト毛嚢キューテクル / Ca^<2+>結合蛋白質 / S100A3 / カルシウム結合タンパク質 / 線構造解析 / peptidylarginine deimase / S100A3,脱イミノ化反応 / ハダニアザミウマ / ミヤコカブリダニ / LC_<50> / ヘキシチアゾックス / 人工飼料 / ナシ / 成長阻害物質 / ミカンハダニ / ヘッドドメイン / 重合・脱重合 / 中間径フィラメント / 蛋白質脱イミノ化 / 蛋白質リン酸化 / がん細胞骨格異常 Less

The function of peptidylarginine deiminase expressed in the retina of chickenPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Hidenari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Ibaraki University
Physiology and application of deimination of humnan hair follicle S100A3
- Principal Investigator
  
  KAWADA Akira
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kinki University
Regulatory Mechanism of Peptidylarginine Deiminase Genes Expressed in the Human Epidermal Cells
- Principal Investigator
  
  KAWADA Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kinki University
Biological function and transcriptional regulation of mouse peptidylarginine deiminase type IV gene, Padi4Principal Investigator
- Principal Investigator
  
  TAKAHARA Hidenari
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Ibaraki University
果樹ハダニ類のバイオコントロールの可能性を秘めた天然物の発見と防除への展開
- Principal Investigator
  
  後藤哲雄
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  植物保護
- Research Institution
  Ibaraki University
Studies on the structure and biological function of human hair follicle peptidylarginine deiminase
- Principal Investigator
  
  KAWADA Aklira
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kinki University
Transcriptional factor and function of mouse and human peptidylarginine deiminase genesPrincipal Investigator
- Principal Investigator
  
  TAKEHARA Hidenari
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  IBARAKI UNIVERSITY
Elucidation of Biological Function of Mouse Peptidylarginine Deiminase by Gene TargetingPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Hidenari
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  IBARAKI UNIVERSITY
ヒト毛細胞特異的ペプチジルアルギニンデイミナーゼのcDNAクローニングと機能解析Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Ibaraki University
大腸菌発現系による蛋白質アルギニン脱イミノ酵素の特性解析と高機能キメラ酵素の創製Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Ibaraki University
ラットおよびヒト表皮型ペプチジルアルギニンデイミナーゼの構造と生理機能の解明Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Ibaraki University
マウス由来ペプチジルアルギニンデイミナ-ゼの大腸菌での発現とその応用Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University
妊娠子宮脱落膜におけるペプチジルアルギニンデイミナ-ゼの発現調節機構と機能の解明Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University
がん細胞骨格異常に果たす蛋白質リン酸化・脱イミノ化の役割
- Principal Investigator
  
  稲垣昌樹
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Aichi Cancer Center Research Institute
ペプチジルアルギニンデイミナ-ゼのエストロゲンによる誘導とその生理的意義Principal Investigator
- Principal Investigator
  
  高原英成
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University
Structure and Function of Peptidylarginine Deiminase and the Regulation of the Gene Expression
- Principal Investigator
  
  SUGAWARA Kiyoshi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Faculty of Agriculture, Ibaraki University
Modulation of Chromosomal Proteins by Peptidylarginine Deiminase and Gene Expression.
- Principal Investigator
  
  SUGAWARA Kiyoshi
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University
Resolution of Reactive Center Structure of Peptidylarginine Deiminase, a Novel Protein Modulating EnzymePrincipal Investigator
- Principal Investigator
  
  TAKAHARA Hidenari
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University
蛋白質シトルリン残基をアルギニン残基に変換する新しい修飾酵素の存在とその性質
- Principal Investigator
  
  SUGAWARA Kiyoshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Ibaraki University

All 2014 2013 2009 2008 2006 2005 2004 Other

All Journal Article Presentation

[Journal Article] Three isozymes of peptidylarginine deiminase in the chicken: Molecular2014
- Author(s)
  Akira Shimizu, Kenji Handa , Tomonori Honda, Naoki Abe, Toshio Kojima, Hidenari Takahara
- Journal Title
  
  Comparative Biochemistry and Physiology, Part B
  
  Volume: 167 Pages: 65-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580128
[Journal Article] Three isozymes of peptidylarginine de imiase in the chiken : Molecular cloning、characterization, and tissue distributi on2014
- Author(s)
  Akira Shimizu、Kenji Handa、Tomonori Honda、Naoki Abe、Toshio Kojima、Hidenar i Takahara
- Journal Title
  
  Comparative Biochemistry and Physio logy, Part B
  
  Volume: 167 Pages: 65-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580128
[Journal Article] Transcriptional regulation of peptidylarginine deiminase expression in human keratinocytes2009
- Author(s)
  S.Ying, S.Dong, A.Kawada, T.Kojima, S.Chavanas, M.C.Mechin, V.Adoue, G.Serre, M.Simon, H.Takahara
- Journal Title
  
  J.Dermatol.Sci. 53
  
  Pages: 2-9
- NAID
  10025331723
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591358
[Journal Article] Specific citrullination causes assembly of a globular S100A3 homotetramer : a putative Ca2+ modulator matures human hair cuticle.2008
- Author(s)
  K.Kizawa, H.Takahara, H.Troxler, P.Kleinert, U.Mochida, C.W.Heizmann
- Journal Title
  
  J.Biol.Chem. 283
  
  Pages: 5004-5013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591358
[Journal Article] Proteomics implicated peptidylarginine deiminase 2 optic nerve citullination in glaucoma pathogenesis2006
- Author(s)
  Bhattacharya S, Crabb JS, Bonilha VL, Gu X, Takahara H, Crabb JW
- Journal Title
  
  Invest Ophth Vis Sci 47(掲載決定)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene(PADI3) in human keratinocytes2006
- Author(s)
  Dong S, Kanno T, Yamaki A, Kojima T, Shiraiwa M, kawada A, Mechin M, Chavanas Serre G, Simon M, Takahara H
- Journal Title
  
  Biochemical Journal 397
  
  Pages: 449-459
- Data Source
  KAKENHI-PROJECT-18591265
[Journal Article] NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes.2006
- Author(s)
  Dong S, Kanno T, Ayako Yamaki A, Kojima T, Shirawa M, Kawada A, Marie-Claire Mechin, MC Chavanas S, Guy Serre G, Simon M, Takahara H
- Journal Title
  
  Biochem.J (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes.2006
- Author(s)
  Dong S, Kanno T, Yamaki A, Kojima T, Shirawa M, Kawada A, Mechin, MC Chavanas S, Serre G, Simon M, Takahara H
- Journal Title
  
  Biochem. J (掲載決定)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Proteomics implicated peptidylarginine deiminase 2 optic nerve citullination in glaucoma pathogenesis2006
- Author(s)
  Bhattacharya S, Crabb JS, Bonilha VL, Gu X, Takahara H, Crabb JW
- Journal Title
  
  Invest Ophth Vis Sci. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and Filaggrin2005
- Author(s)
  Nachat R, Mechin MC, Takahara H, Chavanas S, Charveron M, Serre G, Simon M.
- Journal Title
  
  J. Invest. Dermatol. 124
  
  Pages: 384-393
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and Filaggrin2005
- Author(s)
  Nachat R, Mechin MC, Takahara H, Chavanas S, Charveron M, Serre G, Simon M.
- Journal Title
  
  J.Invest.Dermatol. 124
  
  Pages: 384-393
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors2005
- Author(s)
  Dong S, Kojima T, Shiraiwa M, Mechin MC, Chavanas S, Serve G, Simon M, Kawada A, Takahara H.
- Journal Title
  
  J.Invest.Dermatol. 124
  
  Pages: 1026-1033
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors2005
- Author(s)
  Dong S, Kojima T, Shiraiwa M, Mechin MC, Chavanas S, Serre G, Simon M, Kawada A, Takahara H.
- Journal Title
  
  J. Invest. Dermatol. 124(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Inhibitory effect of mizorubine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macropages2005
- Author(s)
  Zhong B, Tajima M, Takahara H, Nochi H, Tamato K, Tamura N, Kobayashi S, Tamura Y, Ikdeda M, Akimoto T, Yoshino S, Hashimoto H
- Journal Title
  
  Mod Rheumatol 15
  
  Pages: 264-268
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Inhibitory effect of mizorubine on matrix metalloproteinase-1 production in synovial fibroblasts and THP-1 macropages2005
- Author(s)
  Zhong B, Tajima M, Takahara H, Nochi H, Tamoto K, Tamura N, Kobayashi S, Tamura Y, Ikdeda M, Akimoto T, Yoshino S, Hashimoto H
- Journal Title
  
  Mod Rheumatol 15
  
  Pages: 264-268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors2005
- Author(s)
  Dong S, Kojima T, Shiraiwa M, Mechin MC, Chavanas S, Serre G, Simon M, Kawada A, Takahara H.
- Journal Title
  
  J.Invest.Dermatol. 124(印刷中)
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Peptidylarginine deiminase isoforms 1- 3 are expressed in the epidermis and involved in the deimination of K1 and Filaggrin2005
- Author(s)
  Nachat R, Mechin MC, Takahara H, Chavanas S, Charveron M, Serre G, Simon M.
- Journal Title
  
  J.Invest.Dermatol. 124
  
  Pages: 384-393
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations2005
- Author(s)
  Mechin MC, Enji M, Nachat R, Chavanas S, Charveron, M, Ishida-Yamamoto A, Serre G, Takahara H, Simon M.
- Journal Title
  
  Cellular and Molecular Life Sciences 62
  
  Pages: 1984-1995
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI62004
- Author(s)
  Chavanas S, Mechin MC, Takahara H, Kawada A, Nachat R, Serre G, Simon M.
- Journal Title
  
  Gene 330
  
  Pages: 19-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580071
[Journal Article] Refined crystal structure of human Ca^2+/Zn^<2+>-binding S100A3 protein characteraized by two disulphide bridges
- Author(s)
  M.Unno, T.Kawasaki, H.Takahara, C.W.Heizmann, K.Kizawa
- Journal Title
  
  J.Mol.Biol. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591358
[Journal Article] An intronic enhancer driven by NF-_KB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.
- Author(s)
  S.Ying, T.Kojima, A.Kawada, R Nachat, G.Serre, M.Simon, H Takahara
- Journal Title
  
  J Invest Dermatol. 201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591358
[Presentation] Three Isozymes of Peptidyl arginine deiminases in Chicken : Molecul ar cloning, characterization, and tissu e distribution2013
- Author(s)
  Akira Shimizu、Toshio Kojima、Hidenar i Takahara
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  パシフィコ横浜国際会議場
- Year and Date
  2013-09-12
- Data Source
  KAKENHI-PROJECT-23580128
[Presentation] Three Isozymes of Peptidylarginine deiminases in Chicken: Molecular cloning, characterization, and tissue deistribution
- Author(s)
  Ａｋｉｒａ　Ｓｈｉｍｉｚｕ，Ｔｏｓｈｉo Kojima, Hidenari Takahara
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  パシフィコ横浜国際会議場
- Data Source
  KAKENHI-PROJECT-23580128
[Presentation] ニワトリpeptidylarginine deiminase type I の酵素化学的性質の解析と組織は発現
- Author(s)
  清水明、小島俊雄、高原英成
- Organizer
  日本農芸化学会２０１２年度大会
- Place of Presentation
  京都女子大学
- Data Source
  KAKENHI-PROJECT-23580128

1. KAWADA Akira (90160986)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. SUGAWARA Kiyoshi (40007662)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. TEZUKA Tadashi (20013964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ARAKANE Yoshinori (40232045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 稲垣昌樹 (30183007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 中州章 (50198107)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 安藤祥司 (20193104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田部一史 (30073133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 後藤哲雄 (60178449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. FUKAZAWA Chikafusa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKAHARA Hidenari 高原 英成

高原 英成 タカハラ ヒデナリ

高原 秀成 タカハラ ヒデナリ

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Co-Researchers

The function of peptidylarginine deiminase expressed in the retina of chickenPrincipal Investigator

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Biological function and transcriptional regulation of mouse peptidylarginine deiminase type IV gene, Padi4Principal Investigator

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Transcriptional factor and function of mouse and human peptidylarginine deiminase genesPrincipal Investigator

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Elucidation of Biological Function of Mouse Peptidylarginine Deiminase by Gene TargetingPrincipal Investigator

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ヒト毛細胞特異的ペプチジルアルギニンデイミナーゼのcDNAクローニングと機能解析Principal Investigator

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大腸菌発現系による蛋白質アルギニン脱イミノ酵素の特性解析と高機能キメラ酵素の創製Principal Investigator

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ラットおよびヒト表皮型ペプチジルアルギニンデイミナーゼの構造と生理機能の解明Principal Investigator

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マウス由来ペプチジルアルギニンデイミナ-ゼの大腸菌での発現とその応用Principal Investigator

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妊娠子宮脱落膜におけるペプチジルアルギニンデイミナ-ゼの発現調節機構と機能の解明Principal Investigator

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TAKAHARA Hidenari 高原英成

高原英成タカハラヒデナリ

高原秀成タカハラヒデナリ