Sakurai Kazunari 櫻井一成

… Alternative Names

SAKURAI Kazunari 櫻井一成

桜井一成サクライカズナリ

Less

Researcher Number	30129118
Affiliation (Current)	2025: 関西国際大学, 現代社会学部, 教授
Affiliation (based on the past Project Information) *help	2008: 兵庫医科大学, 医学部, 講師 2000 – 2006: 兵庫医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Surgical dentistry / 病態科学系歯学(含放射線系歯学) Except Principal Investigator Surgical dentistry / Surgical dentistry
Keywords	Principal Investigator COX-2 / Immunohistochemistry / Squamous cell carcinoma / Oral mucosa / 免疫組織化学 / 浸潤・転移 / 扁平上皮癌 / 口腔粘膜 / Prognostic factor / In situ hybridization … More / Cell cycle regulating gene / Invasion and metastasis / 湿潤・転移 / 口腔癌(扁平上皮癌) / 口腔 / 予後因子 / in situ hybridization / 細胞周期制御遺伝子 / 口腔癌 / 18 / HPV type 16 / DNA-Topoisomerase IIα / Invasion and Metastasis / Precancerous lesion / COX-2蛋白 / 口腔扁平上皮癌 / 口腔粘膜前癌病変 / TopoIIα / 発癌 / 上皮異形成症 / Topisomerase II alpha / 18型 / HPV16 / Topoisomerase II alpha / 前癌病変 … More Except Principal Investigator 転移 / 口腔癌 / oral cancer / cyclooxygenase (COX)-2 / 扁平上皮癌 / 腫瘍増殖抑制 / COX-2阻害剤 / シクロオキシゲナーゼ(COX)-2 / 予後 / ケモカインレセプター / 浸潤 / squamous cell carcinoma / lymphangiogenesis / nude mouse / metastasis model / chemokine receptor / chemokine / lymph node metastasis / 癌 / リンパ管新生因子 / リンパ管新生 / ヌードマウス / 転移モデル / ケモカイン / リンパ節転移 / COX-2 inhibitor / hamster cheek pouch carcinogenesis / nude mouse transplantation model / metalloproteinases / prognostic factor / invasion and matastasis / シスプラチン感受性 / in vitro浸潤能 / DNA-トポイソメラーゼIIα / MMP / COX-2高発現KB細胞 / ハムスター頬嚢化学発癌 / ヌードマウス移植モデル / メタロプロテナーゼ / 予後因子 / 浸潤・転移 / apoptosis / anticancer drugs / COX-2 inhibitors / tumor growth and metastasis / head and neck cancer / 唾液腺癌 / 前癌病変 / アポトーシス / 抗癌剤 / 腫瘍増殖と転移 / 頭頸部癌 / CXCR4 / 腺様嚢胞癌 Less

Analysis of mechanisms of oral cancer metastasis via chemokine signals and molecular target therapy for inhibition of metastasis
- Principal Investigator
  
  URADE Masahiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hyogo College of Medicine
The role of lymphangiogenetic growth factor and chemokine receptor in lymph nodes metastasis of oral squamous cell carcinoma
- Principal Investigator
  
  KISHIMOTO Hiromitsu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hyogo College of Medicine
Investigation for involvement of COX-2 in invasion and metastasis of oral cancer and inhibitory effect by selective COX-2 inhibitors
- Principal Investigator
  
  URADE MASAHIRO
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hyogo College of Medicine
Relation of abnormal expression of cell cycle regulating factor and outcome of patients with COX-2 expression in the progression of oral carcinomaPrincipal Investigator
- Principal Investigator
  
  SAKURAI KAZUNARI
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hyogo College of Medicine
Expression of cyclooxygenase (COX)-2 in head and neck cancer and inhibitory effect of COX-2 inhibitors on tumor growth
- Principal Investigator
  
  URADE Masahiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Hyogo Medical University
Relation of COX-2 in carcinogenesis and invasion and metastasis of oral cancerPrincipal Investigator
- Principal Investigator
  
  SAKURAI Kazunari
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Hyogo College of Medicine

All 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Expression of cyclooxygenase-2 and DNA topoisomerase II α in precancerous and cancerous lesions of the oral mucosa.2008
- Author(s)
  Segawa E, Sakurai K, Kishimoto H, Takaoka K, Noguchi K, Hashitani S, Hirota S, Urade M.
- Journal Title
  
  Oral Oncol 44
  
  Pages: 664-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck.2008
- Author(s)
  Sakurai K, Segawa E, Takaoka K, Toyohara Y, Tanaka N, Kishimoto H, Urade M.
- Journal Title
  
  Int J Oncol 33
  
  Pages: 1133-1139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Establishment of a nude mouse transplantable model of a human malignant fibrous histiocytoma of the mandible with high metastatic potential to the lung.2008
- Author(s)
  Maeda T, Hashitani S, Zushi Y, Segawa E, Tanaka N, Sakurai K, Urade M.
- Journal Title
  
  J Cancer Res Clin 134
  
  Pages: 1005-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Establishment of nude mouse transplantable model of a human adenoid cystic carcinoma of the oral floor showing metastases to lymph node and lung.2007
- Author(s)
  Hashitani S, Urade M, Zushi Y, Sagawa E, Okui S, Sakurai K.
- Journal Title
  
  Oncol Rep 17
  
  Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Prognostic significance of cyclooxygenase-2 and DNA topoisomerase II α expression in oral carcinoma.2007
- Author(s)
  Sakurai K, Urade M, Noguchi K, Hashitani S, Takaoka K, Segawa E, Kishimoto H.
- Journal Title
  
  Head Neck 29
  
  Pages: 1002-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Prognostic significance of gyclooxygenase-2 and DNA topoisomerase IIα expresstion in oral carcinoma2007
- Author(s)
  Kazunari Sakurai, et. al.
- Journal Title
  
  Head and Neck 29
  
  Pages: 1002-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Establishment and characterization of a human adenoid cystic carcinoma cell line forming colonies cultured in collagen gel and transplantable in nude mice.2007
- Author(s)
  Tanaka N, Urabe K, Hashitani S, Sakurai K, Urade M.
- Journal Title
  
  Oncol Rep 17
  
  Pages: 335-340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Elevated cell migration, invasion and tumorigenicity in human KB carcinoma cells transfected with COX-2 cDNA.2006
- Author(s)
  Takaoka K, Kishimoto H, Segawa E, Hashitani S, Zushi Y, Noguchi K, Sakurai K, Urade M.
- Journal Title
  
  Int J Oncol 29
  
  Pages: 1095-1101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390549
[Journal Article] Promotion of cell differentiation, and suppression of cell growth and cyclooxy-genase-2 expression by differentiation inducing agent in human oral squamous carcinoma SCC25 cells.2005
- Author(s)
  Kuroda J., Urade M., Kishimoto H., Noguchi K., Hashitani S., Sakurai K., Nishimura N., Hashimoto-Tamaoki T.
- Journal Title
  
  International Journal of Oncology 26
  
  Pages: 361-367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592148
[Journal Article] Increased expression of cyclooxygenase (COX) -2 in DMBA-induced hamster cheek pouch carcinogenesis and chemopreventive effect of a selective COX-2 inhibitor.2004
- Author(s)
  Nishimura N., Urade M., Hashitani S., Noguchi K., Mannno Y., Takaoka K., Sakurai K.
- Journal Title
  
  Journal of Oral Pathology and Medicine 66
  
  Pages: 234-243
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592148
[Journal Article] Apoptosis induction and enhancement of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines.2003
- Author(s)
  Hashitani S., Urade M., Nishimura N., Maeda T., Takaoka K., Noguchi K., Sakurai K.
- Journal Title
  
  International Journal of Oncology 23
  
  Pages: 665-672
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592148
[Journal Article] Prognostic significance of cyclooxygenase-2 and DNA topoisomerase II α expression in head and neck carcinoma.
- Author(s)
  Sakurai K., Urade M., Noguchi K., Hashitani S., Takaoka K., Segawa E., Kishimoto H.
- Journal Title
  
  Head and Neck (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592148
[Presentation] Prognostic significance of cyclooxygenase-2 in oral cancer2008
- Author(s)
  Urade M, Kishimoto H, Takaoka K, Segawa E, Noguchi K, Hashitani S, Sakurai K
- Organizer
  XIX Congress of the European Association for Cranio-Maxillo-Facial Surgery
- Place of Presentation
  Bologna, Italy)
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] Establishment and characterization of a human malignant fibrous histiocytoma of the mandible transplantable in nude mice.2007
- Author(s)
  Hashitani S, Toyohara Y, Takaoka K, Noguchi K, Kishimoto H, Sakurai K, Urade M
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] Relationship between expression of CXCR4 and histological type in adenoid cystic carcinoma of the head and neck.2007
- Author(s)
  Sakurai K, Takaoka K, Tanaka N, Kishimoto H, Urade M.
- Organizer
  The European Cancer Conference 14th (ECCO14)
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] Establishment of nude mouse transplantable model of a human adenoid cystic carcinoma showing metastases to the lymph node and lung.2006
- Author(s)
  Hashitani S, Noguchi K, Zushi Y, Okui S, Tanaka N, Sakurai K, Urade M.
- Organizer
  7^<th> Asian Congress on Oral and Maxillofacial Surgery
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] COX-2遺伝子導入によるヒトKB癌細胞の増殖能と浸潤能の亢進2006
- Author(s)
  高岡一樹、浦出雅裕、岸本裕充、橋谷進、豊原幸代、野口一馬、櫻井一成
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] ヌードマウス可移植性ヒト腺様嚢胞癌の移植継代による転移モデルの樹立2006
- Author(s)
  橋谷進、野口一馬、奥井森、瀬川英美、頭司雄介、櫻井一成、浦出雅裕
- Organizer
  第60回日本口腔科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] 3次元培養可能な腺様嚢胞癌細胞株の樹立とその細胞特性について2006
- Author(s)
  田中徳昭、占部一彦、橋谷進、櫻井一成、浦出雅裕
- Organizer
  第60回日本口腔科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] COX-2高発現ヒトKB癌細胞の増殖および浸潤能における一酸化窒素の影響2006
- Author(s)
  高岡一樹、岸本裕充、瀬川英美、頭司雄介、萬野幸代、橋谷進、野口一馬、櫻井一成、浦出雅裕
- Organizer
  第60回日本口腔科学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] ヒト口底腺様嚢胞癌のヌードマウスにおける転移モデルの樹立とその細胞生物学的特性2006
- Author(s)
  橋谷進、野口一馬、豊原幸代、高岡一樹、岸本裕充、櫻井一成、浦出雅裕
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18390549
[Presentation] 3次元培養可能な上顎腺様嚢胞癌由来培養細胞株の細胞特性2006
- Author(s)
  田中徳昭、橋谷進、櫻井一成、浦出雅裕
- Organizer
  第43回日本口腔組織培養学会
- Place of Presentation
  大阪
- Year and Date
  2006-11-11
- Data Source
  KAKENHI-PROJECT-18390549

1. URADE Masahiro (70104883)

# of Collaborated Projects: 6 results

# of Collaborated Products: 21 results
2. KISHIMOTO Hiromitsu (30291818)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. NOGUCHI Kazuma (50309473)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. HASHITANI Susumu (00330449)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
5. TAKAOKA Kazuki (60373122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
6. TANAKA Noriaki (70412012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
7. NISHIMURA NORIHIKO (90330448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SEGAWA Emi

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. ZUSHI Yuusuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

Sakurai Kazunari 櫻井 一成

SAKURAI Kazunari 櫻井 一成

桜井 一成 サクライ カズナリ

Research Projects

Research Products

Co-Researchers

Analysis of mechanisms of oral cancer metastasis via chemokine signals and molecular target therapy for inhibition of metastasis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of lymphangiogenetic growth factor and chemokine receptor in lymph nodes metastasis of oral squamous cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for involvement of COX-2 in invasion and metastasis of oral cancer and inhibitory effect by selective COX-2 inhibitors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relation of abnormal expression of cell cycle regulating factor and outcome of patients with COX-2 expression in the progression of oral carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of cyclooxygenase (COX)-2 in head and neck cancer and inhibitory effect of COX-2 inhibitors on tumor growth

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Relation of COX-2 in carcinogenesis and invasion and metastasis of oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Expression of cyclooxygenase-2 and DNA topoisomerase II α in precancerous and cancerous lesions of the oral mucosa.2008

Author(s)

Journal Title

Data Source

[Journal Article] Relations among expression of CXCR4, histological patterns, and metastatic potential in adenoid cystic carcinoma of the head and neck.2008

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of a nude mouse transplantable model of a human malignant fibrous histiocytoma of the mandible with high metastatic potential to the lung.2008

Author(s)

Journal Title

Data Source

[Journal Article] Establishment of nude mouse transplantable model of a human adenoid cystic carcinoma of the oral floor showing metastases to lymph node and lung.2007

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic significance of cyclooxygenase-2 and DNA topoisomerase II α expression in oral carcinoma.2007

Author(s)

Journal Title

Data Source

[Journal Article] Prognostic significance of gyclooxygenase-2 and DNA topoisomerase IIα expresstion in oral carcinoma2007

Author(s)

Journal Title

Data Source

[Journal Article] Establishment and characterization of a human adenoid cystic carcinoma cell line forming colonies cultured in collagen gel and transplantable in nude mice.2007

Author(s)

Journal Title

Data Source

[Journal Article] Elevated cell migration, invasion and tumorigenicity in human KB carcinoma cells transfected with COX-2 cDNA.2006

Author(s)

Journal Title

Data Source

[Journal Article] Promotion of cell differentiation, and suppression of cell growth and cyclooxy-genase-2 expression by differentiation inducing agent in human oral squamous carcinoma SCC25 cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Increased expression of cyclooxygenase (COX) -2 in DMBA-induced hamster cheek pouch carcinogenesis and chemopreventive effect of a selective COX-2 inhibitor.2004

Sakurai Kazunari 櫻井一成

SAKURAI Kazunari 櫻井一成

桜井一成サクライカズナリ