Shimura Kiyohito 志村清仁

… Alternative Names

SHIMURA Kiyohito 志村清仁

SHIMURA Kenichi 志村清仁

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Researcher Number	30130008
Other IDs
External Links
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 博士研究員
Affiliation (based on the past Project Information) *help	2019: 福島県立医科大学, 医学部, 博士研究員 2014 – 2018: 福島県立医科大学, 医学部, 教授 2006: The University of Tokyo, Graduate School of Engineering, Dept.of Applied Chemistry, Visiting Associate Professor, 大学院工学系研究科, 客員助教授 2005: (財)神奈川科学技術アカデミー, 光化学重点研究室・マイクロ化学グループ, 研究員 1999 – 2001: 帝京大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Analytical chemistry / Living organism molecular science / Structural biochemistry Except Principal Investigator Structural biochemistry
Keywords	Principal Investigator キャピラリー等電点電気泳動 / キャピラリー電気泳動 / キャピラリー / 等電点電気泳動 / capillary / isoelectric focusing / 免疫アフィニティー / APCIEF / ACCIEF / CIEF … More / クローナリティー / モノリスカラム / マイクロカラム / アフィニティーカラム / 免疫応答 / T細胞受容体 / クロマトグラフィー / peptization / peptide / insoluble antigen / prion protein / immunoassay / 限定分解 / レーザー蛍光 / 兔疫測定法 / ペプチド化 / ペプチド / 不溶性抗原 / プリオンタンパク質 / 免疫測定法 / site-directed mutagenesis / capillary isoelectric focusing / fluorescence labeling / deamidation / isolectric point / charge / recombinat antibody / 部位指定変異 / 蛍光標識 / 脱アミド反応 / 等電点 / 電荷 / 組換え抗体 / 結合分析 / 免疫等電点電気泳動 / マイクロ分析 / 翻訳後修飾 / タンパク質 / 抗体カラム / 分離分析 / モドフォーム分析 / 翻訳後修飾体 / 免疫抽出 / modform analysis / PTM / immunoadsorption / electrophoresis … More Except Principal Investigator C.elegans / Frontal affinity chromatography / Multivalent interaction / Specific interaction / Glycosignal / Galectin / C.elegaus / フロンタルアフィニティークロマトグラフィ / フロンタルアフィニティークロマトグラフィー / 多価相互作用 / 特異的相互作用 / 糖鎖シグナル / ガレクチン Less

Development of a new immune-response marker using electrophoresisPrincipal Investigator
- Principal Investigator
  
  Shimura Kiyohito
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  Fukushima Medical University
Pattern analysis of post-translational modification using on-line coupling of immunoadsorption and capillary isoelectric focusing.Principal Investigator
- Principal Investigator
  
  Shimura Kiyohito
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  Fukushima Medical University
Development of the isoelectric immunoassay for the peptide derived from an antigen proteinPrincipal Investigator
- Principal Investigator
  
  SHIMURA Kiyohito
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  The University of Tokyo
  Kanagawa Academy of Science and Technology
Investigation on the origin of charge heterogeneity of antibody by genetic engineeringPrincipal Investigator
- Principal Investigator
  
  SHIMURA Kiyohito
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Teikyo University
Biological significance of multivalent interaction between animal lectins and saccharides.
- Principal Investigator
  
  KASAI Kenichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  Teikyo University

All 2019 2018 2017 2016 2015 2014 2007 2006 2005 Other

All Journal Article Presentation Book Patent

[Book] "Capillary Isoelectric Focusing", in Handbook in Separation Science: Capillary Electromigration Separation Methods (Ed. Colin F. Poole)2018
- Author(s)
  Kiyohito Shimura
- Total Pages
  21
- Publisher
  Elsevier Science
- ISBN
  9780128093757
- Data Source
  KAKENHI-PROJECT-17K05907
[Journal Article] Capillary isoelectric focusing after sample enrichment with immunoaffinity chromatography in a single capillar2016
- Author(s)
  Kiyohito Shimura and Toshihiko Nagai
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Issue: 1 Pages: 39221-39221
- DOI
  10.1038/srep39221
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26410158
[Journal Article] Direct coupling of immobilized metal ion affinity chromatography and capillary isoelectric focusing in a single capillary2015
- Author(s)
  Shimura K, Nagai T.
- Journal Title
  
  J. Electrophor
  
  Volume: 59 Issue: 1 Pages: 7-17
- DOI
  10.2198/jelectroph.59.7
- NAID
  130005117218
- ISSN
  1349-9394, 1349-9408
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26410158
[Journal Article] On-chip connector valve for immunoaffinity chromatography in a microfluidic chip2007
- Author(s)
  Kiyohito Shimura
- Journal Title
  
  Journal of Separation Science (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510183
[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2006
- Author(s)
  Kiyohito Shimura
- Journal Title
  
  Electrophoresis 27(10)
  
  Pages: 1886-1894
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510183
[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2006
- Author(s)
  Kiyohito Shimura
- Journal Title
  
  Electrophoresis 27・10
  
  Pages: 1886-1894
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510183
[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2005
- Author(s)
  Kiyohito Shimura 他5名
- Journal Title
  
  Electrophoresis (in press)
- Data Source
  KAKENHI-PROJECT-17510183
[Journal Article] A mobility moment analysis of molecular interactions by capillary electrophoresis2005
- Author(s)
  Kiyohito Shimura 他4名
- Journal Title
  
  Analytical Chemistry 77・2
  
  Pages: 564-572
- Data Source
  KAKENHI-PROJECT-17510183
[Journal Article] Mobility moment analysis of protein-ligand interactions using a multi-capillary electrophoresis instrument : Competitive affinophoresis of concanavalin A and trypsin2005
- Author(s)
  Kiyohito Shimura 他5名
- Journal Title
  
  J.Electrophoresis 49・2
  
  Pages: 53-60
- NAID
  10016453085
- Data Source
  KAKENHI-PROJECT-17510183
[Patent] 分離分析用キャピラリーデバイス、分離分析用マイクロ流体チップ、タンパク質又はペプチド分析方法、電気泳動装置、及び分離分析用マイクロ流体チップ電気泳動装置2017
- Inventor(s)
  志村清仁、長井俊彦、福原修一、瀬戸善一
- Industrial Property Rights Holder
  福島県立医科大学、日栄工業株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-17K05907
[Patent] CAPILLARY DEVICE FOR SEPARATION AND ANALYSIS,2017
- Inventor(s)
  Kiyohito Shimura et al.
- Industrial Property Rights Holder
  Kiyohito Shimura et al.
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-17K05907
[Patent] CAPILLARY DEVICE FOR SEPARATION AND ANALYSIS2016
- Inventor(s)
  KIYOHITO SHIMURA ET AL
- Industrial Property Rights Holder
  SHIMURA & NICHIEI INDUSTRY
- Industrial Property Rights Type
  特許
- Filing Date
  2016-03-29
- Overseas
- Data Source
  KAKENHI-PROJECT-26410158
[Patent] 分離分析用キャピラリーデバイス、分離分析用マイクロ流体チップ、タンパク質又はペプチド分析方法、電気泳動装置、及び分離分析用マイクロ流体チップ電気泳動装置2014
- Inventor(s)
  志村清仁、長井俊彦、福原修一、瀬戸善一
- Industrial Property Rights Holder
  志村清仁、長井俊彦、福原修一、瀬戸善一
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Overseas
- Data Source
  KAKENHI-PROJECT-26410158
[Patent] タンパク質の測定方法(抗原タンパク質をペプチド化して行う免疫測定法)2005
- Inventor(s)
  高橋克佳, 志村清仁, 松田治男, 青笹正義
- Industrial Property Rights Holder
  シヤープ, 帝京大学, 広島大学
- Industrial Property Number
  2005-257938
- Filing Date
  2005-09-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510183
[Presentation] バイオアフィニティーとキャピラリー等電点電気泳動の結合によるタンパク質電荷バリアント分析2019
- Author(s)
  志村清仁
- Organizer
  日本電気泳動学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] ペプチドの等電点予測のためのアミノ酸残基pKa値の最適化2018
- Author(s)
  志村清仁、風間健太郎、安達　隆
- Organizer
  第69回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] Immunoaffinity Capillary Isoelectric Focusing: Two facile micro analytical platforms for charge variants of protein pharmaceuticals2018
- Author(s)
  Kiyohito Shimura
- Organizer
  ISPPP 2018, International Symposium on the Separation of Proteins, Peptides and Polynucleotides
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] Immunoaffinity Capillary Isoelectric Focusing: Two micro platforms for charge variant analysis of protein2018
- Author(s)
  Kiyohito Shimura
- Organizer
  ITP 2018, 25th International Symposium on Electro- and Liquid Phase-Separation Techniques
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] Capillary isoelectric focusing coupled with immunoaffinity: Two micro platforms for analysis of charge variants produced by post translational modifications2018
- Author(s)
  Kiyohito Shimura
- Organizer
  MSB 2018: The 34th International Symposium on Microscale Separation and Bioanalysis
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] 走査型検出系を有する自動キャピラリー等電点電気泳動装置の再現性評価2018
- Author(s)
  長井俊彦、志村清仁
- Organizer
  第69回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] 免疫キャピラリー等電点電気泳動：タンパク質電荷バリアント構成比に基づく新規バイオマーカー開発に向けて2018
- Author(s)
  志村清仁
- Organizer
  第25回クロマトグラフィーシンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] キャピラリー等電点電気泳動とバイオアフィニティーの結合分析2018
- Author(s)
  志村清仁
- Organizer
  第38回キャピラリー電気泳動シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] 新規バイオマーカーのための免疫電気泳動装置2017
- Author(s)
  志村清仁
- Organizer
  JST新技術説明会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] APCIEFによるエリスロポエチン電荷バリアント分析の問題点とその解決2017
- Author(s)
  志村清仁、長井俊彦
- Organizer
  SCE 2017: 第37回キャピラリー電気泳動シンポジウム
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] 免疫抽出とキャピラリー等電点電気泳動を一体化した分離法のタンパク質医薬分析における可能性2017
- Author(s)
  志村清仁
- Organizer
  第67回日本電気泳動学会シンポジウム　バイオ医薬÷電気泳動：電気泳動でみるバイオ医薬品の特性
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] PDMAコートキャピラリーを用いた紫外部吸収検出によるIEF条件の基礎検討2017
- Author(s)
  長井俊彦、志村清仁
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] タンパク質医薬分析における免疫抽出とキャピラリー等電点電気泳動の直接結合2017
- Author(s)
  志村清仁
- Organizer
  日本分析化学会第66年会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] APCIEFによるエリスロポエチン等電点バリアント分析の最適化2017
- Author(s)
  志村清仁、長井俊彦
- Organizer
  第68回日本電気泳動学会総会
- Data Source
  KAKENHI-PROJECT-17K05907
[Presentation] Direct Coupling of Immunoaffinity Chromatography and Capillary Isoelectric Focusing in a Unified Capillary Device2016
- Author(s)
  Shimura Kiyohito
- Organizer
  BIT's 8th Annual International Congress of Antibodies-2016
- Place of Presentation
  Dalian
- Year and Date
  2016-04-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 抗体アフィニティーカラムとキャピラリー等電点電気泳動の直接結合－第3報　より温和な溶離・陽極液を用いた直接結合分析－2016
- Author(s)
  長井俊彦、志村清仁
- Organizer
  第67回日本電気泳動学会総会
- Place of Presentation
  釧路市
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 免疫磁気分離とキャピラリー等電点電気泳動の直接結合2016
- Author(s)
  瀬戸善一、福原修一、長井俊彦、志村清仁
- Organizer
  第36回キャピラリー電気泳動シンポジウム (SCE 2016)
- Place of Presentation
  徳島市
- Year and Date
  2016-11-09
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 一体型キャピラリーデバイスを用いたエリスロポエチンの等電点パターン分析2016
- Author(s)
  志村清仁、長井俊彦、瀬戸善一、福原修一、山本雅哉、和栗　聡、永尾雅哉
- Organizer
  第67回日本電気泳動学会総会
- Place of Presentation
  釧路市
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 抗体アフィニティーカラムとキャピラリー等電点電気泳動の直接結合2015
- Author(s)
  長井俊彦、志村清仁
- Organizer
  第66回日本電気泳動学会総会
- Place of Presentation
  東京工科大学（東京都大田区）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] アフィニティークロマトと等電点分離の直接結合に最適なキャピラリー電気泳動装置2015
- Author(s)
  志村清仁
- Organizer
  第66回日本電気泳動学会総会
- Place of Presentation
  東京工科大学（東京都大田区）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] APCEによる組換えエリスロポエチンの等電点パターン決定2015
- Author(s)
  志村清仁、長井俊彦、瀬戸善一、福原修一、山本雅哉、和栗聡、永尾雅哉
- Organizer
  第35回キャピラリー電気泳動シンポジウム
- Place of Presentation
  岡山大学（岡山市）
- Year and Date
  2015-11-04
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 金属キレートクロマトグラフィーとキャピラリー等電点電気泳動のオンライン結合
- Author(s)
  志村清仁、長井俊彦
- Organizer
  第74回分析化学討論会
- Place of Presentation
  郡山市
- Year and Date
  2014-05-24 – 2014-05-25
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] アフィニティークロマトグラフィーと等電点電気泳動の直接結合に最適な電気泳動装置
- Author(s)
  志村清仁、長井俊彦、瀬戸善一、福原修一
- Organizer
  第34回キャピラリー電気泳動シンポジウム（SCE2014）
- Place of Presentation
  京都大学　桂キャンパス
- Year and Date
  2014-12-09 – 2014-12-11
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] アフィニティープローブキャピラリー電気泳動による翻訳後修飾パターン分析
- Author(s)
  志村清仁
- Organizer
  第65回日本電気泳動学会総会
- Place of Presentation
  横浜情報文化センター
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] 抗 E-tag 抗体カラムとキャピラリー等電点電気泳動のオンライン結合
- Author(s)
  長井俊彦、志村清仁
- Organizer
  第65回日本電気泳動学会総会
- Place of Presentation
  横浜情報文化センター
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] On-line Coupling of Immunoaffinity Chromatography and CIEF in a Single Capillary
- Author(s)
  Kiyohito Shimura, Toshihiko Nagai
- Organizer
  14th Aisa-Pacific International Symposium on Microscale Separations and Analysis
- Place of Presentation
  京都大学　桂キャンパス
- Year and Date
  2014-12-07 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-26410158
[Presentation] Direct coupling of affinity chromatography and capillary isoelectric focusing in a single capillary
- Author(s)
  Kiyohito Shimura, Toshihiko Nagai
- Organizer
  30th International Symposium on MicroScale Bioseparations
- Place of Presentation
  Pecs, Hungary
- Year and Date
  2014-04-27 – 2014-05-01
- Data Source
  KAKENHI-PROJECT-26410158

1. 長井俊彦 (90180447)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
2. KASAI Kenichi (40001052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HIRABAYASHI Jun (40156691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 荒田洋一郎 (90246017)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木弘行 (30322340)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Shimura Kiyohito 志村 清仁

SHIMURA Kiyohito 志村 清仁

SHIMURA Kenichi 志村 清仁

Research Projects

Research Products

Co-Researchers

Development of a new immune-response marker using electrophoresisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Pattern analysis of post-translational modification using on-line coupling of immunoadsorption and capillary isoelectric focusing.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the isoelectric immunoassay for the peptide derived from an antigen proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation on the origin of charge heterogeneity of antibody by genetic engineeringPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological significance of multivalent interaction between animal lectins and saccharides.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] "Capillary Isoelectric Focusing", in Handbook in Separation Science: Capillary Electromigration Separation Methods (Ed. Colin F. Poole)2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Capillary isoelectric focusing after sample enrichment with immunoaffinity chromatography in a single capillar2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct coupling of immobilized metal ion affinity chromatography and capillary isoelectric focusing in a single capillary2015

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] On-chip connector valve for immunoaffinity chromatography in a microfluidic chip2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Analysis of protein-protein interactions with a multi-capillary electrophoresis instrument2005

Author(s)

Journal Title

Data Source

[Journal Article] A mobility moment analysis of molecular interactions by capillary electrophoresis2005

Author(s)

Journal Title

Data Source

[Journal Article] Mobility moment analysis of protein-ligand interactions using a multi-capillary electrophoresis instrument : Competitive affinophoresis of concanavalin A and trypsin2005

Author(s)

Shimura Kiyohito 志村清仁

SHIMURA Kiyohito 志村清仁

SHIMURA Kenichi 志村清仁