WADA Akihiko 和田明彦

Researcher Number	30131949
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011: 宮崎大学, 医学部, 教授 2010: 九州保健福祉大学, 社会福祉学部, 教授 2003 – 2009: 宮崎大学, 医学部, 教授 1992 – 2002: 宮崎医科大学, 医学部, 教授 1991: 産業医科大学, 医学部・薬理学, 助教授 … More 1988: 産業科大学, 医学部・薬理学, 助教授 1986 – 1988: 産業医科大学, 医学部・薬理学, 助教授 1987: 産業医科大学, 薬理学教室, 助教授 1986: 産業医大, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator General pharmacology / Neurochemistry/Neuropharmacology / Biological Sciences / Obstetrics and gynecology Except Principal Investigator 麻酔学 / Neurochemistry/Neuropharmacology / General pharmacology / Otorhinolaryngology / Applied pharmacology / 応用薬理学・医療系薬学
Keywords	Principal Investigator Gene expression / Calcium / Northern blot / Western blot / Down-regulation / Up-and down-regulation / Binding / Sodium channel / Veratridine / ^<22>Na influx … More / Na channels / lithium / insulin / Neuroprotective drug / Calpain / Protein phosphatase / Protein kinase / Ca^<2+> signaling / Ca^<2+> oscillation / Voltage-dependent Na^+ channels / Exocytosis / Neuroprotective drugs / Protein kinases / Sodium channels / カテコールアミン分泌 / 副腎髄質 / RAMP / 妊娠子宮 / Protein kinase C / Brevetoxin / ^3H-saxitoxin / Expression / Phencyclidine / Potassium / Sodium / Catecholamine secretion / Ion channel / Adrenal medulla / カテコ-ルアミン分泌 / μ-コノトキシン / K^+ / Ca^2+ / Na^+ / ヒストリオニコトキシン / ネオスルガトキシン / ベラトリジン / ブレベトキシン / 電位依存性Naチャンネル / 抗うつ薬 / フェンサイクリジン / コノトキシンGIIIA / ブリベトキシン / サキシトキシン / イオンチャンネル / troglitazone / lysosphosphatidic acid / insulin-like growth factor / Ca2+ overload / cell surface expression / Nav1.7 Na+ channel / glycogen synthase kinase-3 / プリオン・ペプタイド / β-アミロイド・ペプタイド / 血清除去 / 電位依存性Na+チャネル / 副腎髄質クロマフィン細胞 / インターナリゼーション / β-アミロイド / GSK-3β / IGF-I / 細胞膜発現調節 / Hsp90 / lysophosphatidic acid / glycogen synthase kinase-3β / heat shock protein 90 / 糖鎖付加 / 翻訳後修飾 / Na^+チャネル / トログリタゾン / lysohosphatidic acid / リチウム / insulin-like growth factor-I / Ca^<2+>過負荷 / 細胞膜発現 / Na_v1.7Na^+チャネル / Ca-ATPase / Calcineurin / Voltage-dependent sodium channels / Ca^<2+>signaling / Ca^<2+>oscillation / Pregnant uterus / Vascular smooth muscle cell / Glia cell / Brain microvessel endothelial cell / Receptor / Bioactive peptide / Catecholamine / Brain microvessels / Autocrine regulation / Nicotinic receptors / Tyrosine hydroxylase / Uterus / Adrenomedullin family / Oligodendroglial cells / Choroid plexus / Microvessels / Adrenal chromaffin cells / CRLR / PAMP / Adrenomedullin / 平滑筋細胞 / グリア筋細胞 / 脳微小血管内皮細胞 / 遺伝子発現 / レセプター / 生理活性ペプチド / Antiepileptics / C kinase family / 【^3H】-サキシトキシン / 【K^+】 / 【Ca^(2+)】 / 【Na^+】 / Naポンプ / イオン・チャンネル / mRNA発現増加 / 早産 / 脱落膜 / 胎盤 / 子宮収縮抑制 / オキシトシン / プロスタグランジンF_<2α> / ブラジキニン / AMノックアウトマウス / RAMP2 / 子宮収縮制御 / アドレノメデュリン / Internalization / C kinase isoform / ^<22>Na+ influx / C kinase / A kinase / C Kinase / A Kinase / Phorbol esters / Protein Kinase C / Diacylglycerol / ^3H‐Saxitoxin / Down‐regulation / αーサソリ毒 / テトロドトキシン / ヴェラトリジン / 遺伝子 / ^3Hーサキシトキシン / ^<22>Na / Naチャンネル / 副腎髄質細胞 … More Except Principal Investigator 発現調節 / Aquaporin / 副腎髄質 / Anesthetics / Sodium / Calcium / Dexamethasone / regulation of expression / 脳浮腫 / アストロサイト / アクアポリン / 脳微小血管 / イオン・チャンネル / カテコールアミン分泌 / Insulin receptor substrate / Glycogen synthase kinase-3β / 脳・神経 / 神経変性疾患 / インスリン抵抗性 / インスリンシグナリング / インスリン受容体 / インスリン受容体シグナル / 培養副腎髄質細胞 / 細胞内輸送 / 細胞膜発現調節 / Naチャネル / Catecholamine secretion / Binding site / Ion channel / 麻酔薬 / イオンチャンネル / アセチルコリン受容体 / Anesthetics. / Secretion / Ion channels / Catecholamine / Adrenal medulla / Immunohistocemistru / lippopolysaccaride / exudative otitis media / 細胞・組織 / 蛋白質 / 生体分子 / Northern blotting / 免疫染色法 / lipopolysaccaride / 滲出性中耳炎 / agrin / glucocorticoid / raft / brain edema / endothelial cells / aquaporin / brain microvessel / 網膜 / アグリン / 糖質コルチコイド / ラフト / 内皮細胞 / localization / intracellular trafficking / nerve growth factor / cell differentiation / cell adhesion molecule / β-subunit / voltage-dependent Na+ channel / MAPキナーゼ / PC12細胞 / GFP / 強制発現 / 分化 / 電位依存性Na+チャネル / 局在 / 神経成長因子 / 細胞分化 / 細胞接着分子 / β-サブユニット / 電位依存性Na^+チャネル / Immortalized cell / Cytotoxic edema / Regulation of expression / Astrocytes / hypoxia / Ischemia / Cultured endothelial cell / Cerebral microvessel / 培養 / ウエスタンブロット / RT-PCR / 水チャネル / 不死化細胞 / 細胞障害性浮腫 / 虚血・低酸素 / 培養内皮細胞 / premature labor / mRNA expression / decidua / placenta / pregnant uterus / tocolysis / myometrium / adrenomedullin / 早産 / mRNA発現 / 脱落膜 / 胎盤 / 妊娠子宮 / 子宮収縮抑制 / 子宮平滑筋 / アドレノメデュリン / アパミン / 全身麻酔薬 / K^+ / Ca^<2+> / Na^+ / 【Ca^(2+)】 / 【Na^+】 / ハロセン / ドロペリドール / ケタミン / 神経障害 / 神経保護 / 認知症 / 細胞内情報伝達 / 生理活性物質 / アルツハイマー病 / 中枢・末梢神経薬理学 / SAPK / p38 MAPK / JNK / p38MAPK / ERK / MAPKファミリー / 血清除去 / 電位依存性Naチャネル / Caイオン / イムノフィリン / 神経保護薬 / MAPカイネース / プロテインカイネースC Less

Investigation of the regulatory mechanism of neuronal insulin receptor signaling in pursuit of the improvement of insulin resistance.
- Principal Investigator
  
  YANAGITA Toshihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Miyazaki
Insulin signaling in the neuronal cells : regulation of its expression by therapeutic drugs and search for novel neuroprotective drugs
- Principal Investigator
  
  柳田俊彦
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Miyazaki
Regulation of the apuaporins expression in the middle ear : Analysis of the exudative otitis media
- Principal Investigator
  
  TOYAMA Katsuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  University of Miyazaki
アドレノメデュリンの妊娠子宮・収縮抑制機序:早産治療薬としての基礎研究Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  University of Miyazaki
Regulatory mechanisms of expression and localization of aquaporin water channels in brain microvessels
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Miyazaki
Voltage-dependent Na+ channel: quality control and stress response.Principal Investigator
- Principal Investigator
  
  WADA Akihiko
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Miyazaki
Physiological function of voltage-dependent Na^+ channel β-subunit as an adhesion molecule
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  University of Miyazaki
  宮崎医科大学
Inhibitory effect of adrenomedullin on uterine contraction
- Principal Investigator
  
  YANAGITA Toshihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Miyazaki Medical College
Regulatory mechanism of aquaporin expression in cerebral microvessels : its pathophysiological significance
- Principal Investigator
  
  KOBAYASHI Hideyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  宮崎医科大学
Naチャネルの細胞膜発現調節機構におけるMAPカイネースの役割
- Principal Investigator
  
  柳田俊彦
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
Regulation of cell surface expression of voltage-dependent sodium channels by multiple calcium signalings : their mRNA levels and intracellular traffickingPrincipal Investigator
- Principal Investigator
  
  WADA Akihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Miyazaki Medical College
Naチャネルの細胞膜発現調節:サブユニットmRNA変動と細胞内輸送・局在化機構
- Principal Investigator
  
  YANAGITA Toshihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
Physiological function and gene expression of adremnomedullinfamily : adrenal medullary cells and isolated blood vesselsPrincipal Investigator
- Principal Investigator
  
  WADA Akihiko
- Project Period (FY)
  1998 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Miyazaki Medical College
Intracellular mechanisms regulating cell surface expression of Na channels : Na channel subunit mRNA levels and intracellular trafficking.Principal Investigator
- Principal Investigator
  
  WADA Akihiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Miyazaki Medical College
Cカイネースによる細胞膜Naチャネルdown-regulationの細胞内機序Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
CカイネースによるNaチャネル発現の制御と細胞応答の修飾Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
CカイネースおよびAカイネースによる転写調節蛋白の修飾とNaチャネル発現の制御Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
培養副腎髄質細胞における転写調節因子の変動とNaチャンネル発現の制御Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
向神経・精神薬による電位依存性Naチャンネル遺伝子発現の変動Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  宮崎医科大学
培養副腎髄質電位依存性Naチャンネル遺伝子発現の変動と薬物作用の解析Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Occupational and Environmental Health, Japan
副腎髄質の電位依存性Kチャンネル並びにCa依存性Kチャンネルに対する麻酔薬の影響
- Principal Investigator
  
  緒方政則
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, Japan
Characterization of membrane proteins involved in catecholamine secretion and analysis on drug action in cultured adrenal medullary cells.Principal Investigator
- Principal Investigator
  
  WADA Akihiko
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Occupational and Environmental Health, School of Medicine
Action of anesthetics on acetylcholine receptor and voltage-dependent Na channel in cultured adrenal medullary cells.
- Principal Investigator
  
  SHIGEMATSU Akio, 高良裕
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, School of Medicine.
カテコールアミン分泌過程におけるNaチャンネルKチャンネル並びにNaポンプの役割Principal Investigator
- Principal Investigator
  
  和田明彦
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Occupational and Environmental Health, Japan
Naチャンネル,Caチャンネル並びにKチャンネルに対する麻酔薬の影響-培養副腎髄
- Principal Investigator
  
  TAKARA Hiroshi
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  麻酔学
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Book

[Book] 心臓ナビゲーター2005
- Author(s)
  和田明彦
- Publisher
  メディカルトレビュー社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Book] 心臓ナビゲーター2004
- Author(s)
  和田明彦
- Total Pages
  4
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Insulin-induced neurite-like process outgrowth : Acceleration of tau protein synthesis via a phosphoinositide 3-kinase2011
- Author(s)
  Nemoto T, Yanagita T, Satoh S, Maruta T, Kanai T, Murakami M, Wada A
- Journal Title
  
  Neurochemistry International
  
  Volume: 59 Pages: 880-888
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Dexmedetomidine and clonidine inhibit the function of Na_V1.7 independent of α_2-adrenoceptor in adrenal chromaffin cells2011
- Author(s)
  Maruta T, Nemoto T, Satoh S, Kanai T, Yanagita T, Wada A, Tsuneyoshi I
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 25 Issue: 4 Pages: 549-557
- DOI
  10.1007/s00540-011-1168-6
- NAID
  10029601166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Dexmedetomidine and clonidine inhibit the function of Na_V1. 7 independent of α_2-adrenoceptor in adrenal chromaffin cells.2011
- Author(s)
  Maruta T, Nemoto T, Satoh S, Kanai T, Yanagita T, Wada A, Tsuneyoshi I
- Journal Title
  
  Journal of Anesthesia
  
  Volume: 25 Pages: 549-557
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Insul-in-induced neurite-like process outgrowth : Acceleration of tau protein synthesis via a phosphoinositide 3-kinase～mammalian target of rapamycin pathway2011
- Author(s)
  Nemoto T, Yanagita T, Satoh S, Maruta T, Kanai T, Murakami M, Wada A
- Journal Title
  
  Neurochemistry International
  
  Volume: 59 Issue: 6 Pages: 880-888
- DOI
  10.1016/j.neuint.2011.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Distinct regulation of insulin receptorsubstrate-1 and-2 by 90-kDa heat-shock protein in adrenal chromaffin cells2010
- Author(s)
  Yoshikawa N, Nemoto T, Satoh S, Maruta T, Yanagita T, Chosa E, Wada A
- Journal Title
  
  Neurochemistry International
  
  Volume: 54 Pages: 497-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Homologous posttranscriptional regulation of insulin-like growth factor-I receptor level via glycogen synthase kinase-3β and mammalian target of rapamycin in adrenal chromaffin cells : effect on tau phosphorylation2010
- Author(s)
  Nemoto T, Satoh S, Maruta T, Kanai T, Yoshikawa N, Miyazaki S, Yanagita T, Wada A
- Journal Title
  
  Neuropharmacology
  
  Volume: 58 Pages: 1097-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] グリコーゲン合成酵素キナーゼ3β2010
- Author(s)
  根本隆行、柳田俊彦、和田明彦
- Journal Title
  
  日本薬理学雑誌
  
  Volume: 135 Pages: 171-172
- NAID
  10029416762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.2010
- Author(s)
  Yoshikawa N, Nemoto T, Satoh S, Maruta T, Yanagita T, Chosa E, Wada A.
- Journal Title
  
  Neurochemistry International
  
  Volume: 56 Pages: 42-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Homologous posttranscriptional regulation of insulin-like growth factor-I receptor level via glycogen synthase kinase-3β and mammalian target of rapamycin in adrenal chromaffin cells : effect on tau phosphorylation.2010
- Author(s)
  Nemoto T, Satoh S, Maruta T, Kanai T, Yoshikawa N, Miyazaki S, Yanagita T, Wada A.
- Journal Title
  
  Neuropharmacology
  
  Volume: 58 Pages: 1097-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Na_V1. 7-Ca<2+> influx-induced increased phosphorylations of extracellular signal-regulated kinase(ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3β: priming of Na_V1. 7 gating by ERK and p382010
- Author(s)
  Nemoto T, Miyazaki S, Kanai T, Maruta T, Satoh S, Yoshikawa N, Yanagita T, Wada A
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 640 Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Nav1.7-Ca^<2+> influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuatetau phosphorylation via glycogen synthase kinase-3β : priming of Nav1.7 gating by ERK and p38.2010
- Author(s)
  Nemoto T, Miyazaki S, Kanai T, Maruta T, Satoh S, Yoshikawa N, Yanagita T, Wada A.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 640 Pages: 20-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics2009
- Author(s)
  Wada A.
- Journal Title
  
  Front Biosci 14
  
  Pages: 1558-1570
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Na_V1. 7 sodium channel-induced Ca^<2+> influx decreases tau phosphorylation via glycogen synthase kinase-3β in adrenal chromaffin cells.2009
- Author(s)
  Kanai T, Nemoto T, Yanagita T, Maruta T, Satoh S, Yoshikawa N, Wada A
- Journal Title
  
  Neurochemistry International
  
  Volume: 54 Pages: 497-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Drug development targeting the glycogen synthase kinase-3β(GSK-3β)-mediated signal transduction pathway : the role of GSK-3β in the maintenance of steady-state levels of insulin receptor signaling molecules and Nav1. 7 sodium channel in adrenal chromaffin2009
- Author(s)
  Nemoto T, Yanagita T, Kanai T, Wada A
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 109 Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Chronic lithium treatment up-regulates cell surface Na_V1. 7 sodium channels via inhibition of glycogen synthase kinase-3 in adrenal chromaffin cells : enhancement of Na^+ influx, Ca^<2+> influx and catecholamine secretion after lithium withdrawal2009
- Author(s)
  Yanagita T, Maruta T, Nemoto T, Uezono Y, Matsuo K, Satoh S, Yoshikawa N, Kanai T, Kobayashi H, Wada A
- Journal Title
  
  Neuropharmacology
  
  Volume: 57 Pages: 311-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] Drug development targeting the glycogen synthase kinase-3β (GSK-3β)-mediated signal transduction pathway : the role of GSK-3βin the maintenance of steady-state levels of insulin receptor signaling molecules and Na(v)1.7 sodium channel in drenal chromaffin cells2009
- Author(s)
  Nemoto T, Yanagita T, Kanai T, Wada A.
- Journal Title
  
  J Pharmacol Sci 109
  
  Pages: 157-161
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Lithium and neuropsychiatric therapeutics : neuroplasticity via glycogen synthase kinase-3β,β-catenin, and neurotrophin cascades2009
- Author(s)
  Wada A
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 110 Pages: 14-28
- NAID
  10025736349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500350
[Journal Article] 疾患と神経新生 : 糖尿病2008
- Author(s)
  柳田俊彦、根本隆行、和田明彦
- Journal Title
  
  Clinical Neuroscience 26
  
  Pages: 884-886
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Proteasomal degradation of IRS-2, but not RS-1 by calcineurin inhibition : attenuation of insulin-like growth factor-I-induced GSK-3β and ERK pathways in adrenal chromaffin cells2008
- Author(s)
  Satoh S, Yanagita T, Maruta T, Nemoto T, Yoshikawa N, Kobayashi H, Tono T, Wada A.
- Journal Title
  
  Neuropharmacology 55
  
  Pages: 71-79
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Regulation of Akt mRNA and protein levels by glycogen synthase kinase-3βin adrenal chromaffin cells : effects of LiCl and SB2167632008
- Author(s)
  Nemoto T, Kanai T, Yanagita T, Satoh S, Maruta T, Yoshikawa N, Kobayashi H, Wada A.
- Journal Title
  
  Eur J Pharmacol 586
  
  Pages: 82-89
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Voltage-dependent Na(v)1.7 sodium channels : multiple roles in adrenal chromaffin cells and peripheral nervous system2008
- Author(s)
  Wada A, Wanke E, Gullo F, Schiavon E.
- Journal Title
  
  Acta Physiol (Oxf) 192
  
  Pages: 221-231
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Voltage-dependent Na_V1.7 sodium channels ; multiple roles in adrenal chromaffin cells and peripheral nervous system.2008
- Author(s)
  Wada A, et al.
- Journal Title
  
  Acta Physiologica (Oxford) 192
  
  Pages: 221-231
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Lysophosphatidic acid-LPA_1 receptor-Rho-Rho kinase-induced up-regulation of Nav1.7 sodium channel Mrna and protein in adrenal chromaffin cells : enhancement of ^<22>Na^+ influx, ^<45>Ca^<2+>. Influx and catecholamine secretion2008
- Author(s)
  Maruta T, Yanagita T, Matsuo K, Uezono Y, Satoh S, Nemoto T, Yoshikawa N, Kobayashi H, Takasaki M, Wada A.
- Journal Title
  
  J Neurochem 105
  
  Pages: 401-412
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Lithium inhibits function of voltage e-dependent sodium channels and catechola mine secretion independent of glycogen synthase kinase-3 in; adrenal chromaffin cells2007
- Author(s)
  Yanagita T, Maruta T, Uezono Y, Aatoh S, Yoshikawa N, Nemoto T, Kobayashi H, Wada A.
- Journal Title
  
  Neuropharmacology 53(7)
  
  Pages: 881-889
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Lithium inhibits function of voltagedependent sodium channels and catecholamine secretion independent of glycogen synthase kinase-3 in adrenal chromaffin cells2007
- Author(s)
  Yanagita T, Maruta T, Uezono Y, Satoh S, Yoshikawa N, Nemoto T, Kobayashi H, Wada A.
- Journal Title
  
  Neuropharmacology 537
  
  Pages: 881-889
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Voltage-dependent Na_v1.7 sodium channels : multiple roles in adrenal chromaffin cells and peripheral nervous system.2007
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Acta Physiological (Oxford) (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Lithium inhibits function of voltage e-dependent sodium channels and catechola mine secretion independent of glycogen synthase kinase-3 in ; adrenal chromaffin cells2007
- Author(s)
  佐藤伸矢、和田明彦, 他
- Journal Title
  
  Neuropharmacology 53(7)
  
  Pages: 881-889
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Glycogen synthase kinase-3β : homologous regulation of cell surface insulin receptor level via controlling insulin receptor Mrna stability in adrenal chromaffin cells2007
- Author(s)
  Yokoo H, Nemoto T, Yanagita T, Satoh S, Yoshikawa N, Maruta T, Wada A.
- Journal Title
  
  J Neurochem 103
  
  Pages: 1883-1896
- Data Source
  KAKENHI-PROJECT-19500326
[Journal Article] Differential expression of Kir4.1 and aquaporin 4 in the retina from endotoxin-induced uveitis rat.2007
- Author(s)
  Liu X.Q., Kobayashi H., Jin Z.B., Wada A., Nao-I N.
- Journal Title
  
  Molecular Vision 13
  
  Pages: 309-317
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Voltage-dependent Nav1.7 sodium channels : multiple roles in adrenal chromaffin cells and peripheral nervous system.2007
- Author(s)
  Wada A et al.
- Journal Title
  
  Acta Physiological (Oxford) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Enhancement of insulin-induced PI3K/Akt/GSK-3 beta and ERK signaling by neuronal nicotinic receptor/PKC-alpha/ERK pathway : up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells.2006
- Author(s)
  Sugano T., Yanagita T., Yokoo H., Satoh S., Kobayashi H., Wada A.
- Journal Title
  
  Journal of Neurochemistry 98
  
  Pages: 20-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Inducion of apuaporin 1 by dexamethasone in lipid rafts in imortalized brain microvascular endothelial cells2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Journal Title
  
  Brain Research 1123
  
  Pages: 12-19
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Constitutive activity of glycogen synthase kinase-3β : positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells2006
- Author(s)
  Nemoto T, Yokoo H, Satoh S, Yanagita T, Sugano T, Yoshikawa N, Maruta T, Kobayashi H, Wada A.
- Journal Title
  
  Brain Research 1100
  
  Pages: 1-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Roles of voltage-dependent sodium channels in neuronal development, pain, and neurodegeneration.2006
- Author(s)
  Akihiko Wada
- Journal Title
  
  Journal of Pharmacological Sciences 102・3
  
  Pages: 253-268
- NAID
  10020344805
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Induction of aquaporin 1 by dexamethasone in lipid rafts in immortalized brain microvascular endothelial cells2006
- Author(s)
  Kobayashi H., Yokoo H., Yanagita T., Satoh S., Kis B., Deli M., Niwa M., Wada A.
- Journal Title
  
  Brain Research 1123
  
  Pages: 12-19
- NAID
  120007122978
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Enhancement of insulin-induced P13K/Akt/GSK-3β and ERK signaling by neuronal nicotinic receptor/PKC-α/ERK pathway : up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Journal Title
  
  Journal of Neurochemistry 98
  
  Pages: 20-33
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Enhancement of insulin-induced P13K/Akt/GSK-3β and ERK signaling by neuronal nicotinic receptor/PKC- α/ERK pathway : up-regulation of IRS-1/-2 mRNA and protein in adrenal chromaffin cells2006
- Author(s)
  Sugano T, Yanagita T, Yokoo H, Satoh S, Kobayashi H, Wada A.
- Journal Title
  
  Journal of Neurochemistry 98
  
  Pages: 20-33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Constitutive activity of glycogen synthase kinase-3β : positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Journal Title
  
  Brain Research 1110
  
  Pages: 1-12
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Roles of voltage-dependent sodium channels in neuronal development, pain, and neurodegernation.2006
- Author(s)
  Wada A
- Journal Title
  
  Journal of Pharmacological Sciences 102(3)
  
  Pages: 253-268
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Inducion of apuaporin 1 by dexamethasone in lipid rafts in imortalized brain microvascular endothelial cells2006
- Author(s)
  Kobayashi H, Yanagita T, Sato S, Kis B, Deli M, Wada A.
- Journal Title
  
  Brain Research 1123
  
  Pages: 12-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Journal Article] Constitutive activity of glycogen synthase kinase-3beta : Positive regulation of steady-state levels of insulin receptor substrates-1 and-2 in adrenal chromaffin cells.2006
- Author(s)
  Nemoto T., Yokoo H., Satoh S., Yanagita T., Sugano T., Yoshikawa N., Maruta T., Kobayashi H., Wada A.
- Journal Title
  
  Brain Research 1110
  
  Pages: 1-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Roles of voltage-dependent sodium channels in neuronal development, pain, and neurodegernation.2006
- Author(s)
  Akihiko Wada
- Journal Title
  
  Journal of Pharmacological Sciences 102・3
  
  Pages: 253-268
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Lithium : potential therapeutics against acute brain injuries and chronic neurodegenerative diseases.2005
- Author(s)
  Wada A et al.
- Journal Title
  
  Journal of Pharmacological Sciences 99(4)
  
  Pages: 307-321
- NAID
  10025731486
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics.2005
- Author(s)
  Wada A et al.
- Journal Title
  
  Journal of Pharmacological Sciences 99(2)
  
  Pages: 128-143
- NAID
  10025730645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics2005
- Author(s)
  Wada A.et al.
- Journal Title
  
  J. Pharmacol. Sci. 99
  
  Pages: 128-142
- NAID
  10025730645
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics.2005
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Journal of Pharmacological Sciences 99・2
  
  Pages: 128-143
- NAID
  10025730645
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Insulin induces internalization of the 5-HT2A receptor expressed in HEK293 cells.2005
- Author(s)
  Ohkura M., Tanaka N., Kobayashi H., Wada A., Nakai J., Yamamoto R.
- Journal Title
  
  European Journal of Pharmacology 518
  
  Pages: 18-21
- NAID
  40015392245
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Lithium : potential therapeutics against acute brain injuries and chronic neurodegenerative diseases.2005
- Author(s)
  Wada A.et al.
- Journal Title
  
  J. Pharmacol. Sci. 99
  
  Pages: 307-321
- NAID
  10025731486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Relaxant effect of adrenomedullin on bovine isolated iris sphincter muscle under resting conditions.2005
- Author(s)
  Uchikawa Y., Okano M., Sawada A., Asada Y., Kobayashi H., Wada A., Nao-i N., Ohkura M., Tanaka N., Yamamoto R.
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology 32
  
  Pages: 675-680
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] Lithium : potential therapeutics against acute brain injuries and chronic neurodegenerative diseases.2005
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Journal of Pharmacological Sciences 99・4
  
  Pages: 307-321
- NAID
  10025731486
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Lithium : Potential therapeutics against acute brain injuries And chronic neurodegenerative diseases.2005
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Journal of Pharmacological Sciences 99・4
  
  Pages: 307-321
- NAID
  10025731486
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Lithium : potential therapeutics against acute brain injuries and chronic neurodegenerative diseases.2005
- Author(s)
  Wada A.et al.
- Journal Title
  
  J.Pharmacol.Sci. 99
  
  Pages: 307-321
- NAID
  10025731486
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics.2005
- Author(s)
  Wada A., Yokoo H., Yanagita T., Kobayashi H.
- Journal Title
  
  Journal of Pharmacological Sciences 99
  
  Pages: 128-143
- NAID
  10025730645
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] New twist on neuronal insulin receptor signaling in health, disease, and therapeutics2005
- Author(s)
  Wada A.et al.
- Journal Title
  
  J.Pharmacol.Sci. 99
  
  Pages: 128-143
- NAID
  10025730645
- Data Source
  KAKENHI-PROJECT-17590473
[Journal Article] The adrenomedullin family and sympathoadrenal system.2004
- Author(s)
  Wada A
- Journal Title
  
  Nippon Rinsho 62(Suppl 9)
  
  Pages: 252-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] アドレノメデュリン薬理作用と生理作用副腎髄質交感神経に対する作用.2004
- Author(s)
  和田明彦
- Journal Title
  
  日本臨床 62・Suppl9
  
  Pages: 252-255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Regulation of cell surface expression of voltage-dependent Na_v1.7 sodium channels : mRNA stability and posttranscriptional control in adrenal chromaffin cells.2004
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1954-1966
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Regulation of cell surface expression of voltage-dependent NaV1.7 sodium channels : mRNA stability and posttranscriptional control in adrenal chromaffin cells.2004
- Author(s)
  Wada A.et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1954-1966
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500263
[Journal Article] アドレノメデュリン薬理作用と生理作用副賢髄質交感神経系に対する作用2004
- Author(s)
  和田明彦
- Journal Title
  
  臨床分子内分泌学(1)(日本臨床) 62・Suppl 9
  
  Pages: 252-255
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Regulation of cell surface expression of voltage-dependent Na_v1.7 sodium Channels : mRNA stability and posttranscriptional control in adrenal chromaffin cells.2004
- Author(s)
  Akihiko Wada et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1954-1966
- Data Source
  KAKENHI-PROJECT-16300119
[Journal Article] Regulation of cell surface expression of voltage-dependent Nav1.7 sodium channels : mRNA stability and posttranscriptional control in adrenal chromaffin cells.2004
- Author(s)
  Wada A et al.
- Journal Title
  
  Frontiers in Bioscience 9
  
  Pages: 1954-1966
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300119
[Presentation] インスリンによる神経様突起伸張:PI3K～mTOR経路を介したtau蛋白合成促進2012
- Author(s)
  根本隆行、柳田俊彦、和田明彦、村上学
- Organizer
  第85回日本薬理学会年会
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] アルコールはインスリン受容体シグナルを抑制する2012
- Author(s)
  柳田俊彦、根本隆行、宮崎智、和田明彦
- Organizer
  第83回日本薬理学会年会
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] 単離副腎クロマフィン細胞の神経様分化:インスリンによるtau蛋白合成促進2011
- Author(s)
  根本隆行、柳田俊彦、和田明彦、村上学
- Organizer
  第64回日本薬理学会西南部会
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリン受容体発現のHsp90とコシャペロンによる制御2011
- Author(s)
  柳田俊彦、根本隆行、和田明彦、村上学
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリン受容体シグナルにおける正と負の発現調節機構2011
- Author(s)
  根本隆行、柳田俊彦、和田明彦、村上学
- Organizer
  第84回日本薬理学会年会
- Year and Date
  2011-03-24
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Function and cell surface expression of insulin receptor and IGF-I receptor in neuronal cells2010
- Author(s)
  Yanagita T, Nemoto T, Wada A
- Organizer
  BIT Life Sciences 3rd Annual Protein and Peptide Conference
- Year and Date
  2010-03-22
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリンはPI3K/mTOR経路を介してtau蛋白量を増加させる2010
- Author(s)
  根本隆行、柳田俊彦、宮崎智、和田明彦
- Organizer
  第83回日本薬理学会年会
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] ERKとp38によるtauリン酸化, Nav1. 7チャネルの制御2010
- Author(s)
  宮崎智、根本隆行、金井裕、柳田俊彦、和田明彦
- Organizer
  第83回日本薬理学会年会
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Posttranscriptional regulation of IGF-I receptor via GSK-3β and mTOR in adrenal chromaffin cells2010
- Author(s)
  Nemoto T, Yanagita T, Wada A
- Organizer
  20th Japan-Korea Joint Seminar on Pharmacology
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリンによる神経様突起伸長:PI3K/mTOR経路を介したtau蛋白合成促進2010
- Author(s)
  根本隆行、柳田俊彦、和田明彦
- Organizer
  第63回日本薬理学会西南部会
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Insulin/insulin-like growth factor-I(IGF-I)受容体シグナル分子群発現調節機序の解析2009
- Author(s)
  根本隆行、柳田俊彦、宮崎智、和田明彦
- Organizer
  第13回宮崎Neuroscience研究会
- Year and Date
  2009-09-12
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリン様成長因子受容体の発現調節機構2009
- Author(s)
  根本隆行、柳田俊彦、金井祐、宮崎智、和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Insulin-like growth factor-I受容体発現調節機構の解析2009
- Author(s)
  根本隆行、柳田俊彦、宮崎智、和田明彦
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] インスリン受容体とIGF-I受容体の細胞膜発現調節機序2009
- Author(s)
  柳田俊彦、根本隆行、和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] ERK, p38 MAPKによるNav1. 7 Na+チャネルの制御2009
- Author(s)
  宮崎智、根本隆行、金井祐、柳田俊彦、和田明彦
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] 神経系のインスリン受容体シグナル分子群の機能・発現調節機構2009
- Author(s)
  柳田俊彦、根本隆行、宮崎智、和田明彦
- Organizer
  トランスポーター研究会第3回九州部会シンポジウム
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] エタノールによるインスリン容体シグナルの抑制2009
- Author(s)
  柳田俊彦、根本隆行、宮崎智、和田明彦
- Organizer
  第62回日本薬理学会西南部会
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] 電位依存性Nav1. 7 Na+チャネルによるtauリン酸化の制御2009
- Author(s)
  宮崎智、根本隆行、柳田俊彦、和田明彦
- Organizer
  第62回日本薬理学会西南部会
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Glycogen synthase kinase-3βによるinsulin/insulin-like growth factor-I受容体シグナル分子群の発現調節2009
- Author(s)
  根本隆行、柳田俊彦、宮崎智、和田明彦
- Organizer
  第62回日本薬理学会西南部会
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Na_v1.7 Na^+チャネル活性はglycogen synthasekinase-3βを介してtauリン酸化を抑制する2009
- Author(s)
  金井祐、柳田俊彦、根本隆行、宮崎智、和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 抗躁薬リチウムによる電位依存性Na+チャネルの機能・発現調節:GSK-3β非依存性の機能抑制とGSK-3β依存性の細胞膜発現増加2009
- Author(s)
  柳田俊彦、丸田豊明、上園保仁、松尾清隆、吉川教恵、根本隆行、和田明彦
- Organizer
  日本分子生物学会第9回春季シンポジウム
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21500350
[Presentation] Na_v1.7 Na^+チャネルの活性化はERKとp38のリン酸化を増加する2009
- Author(s)
  宮崎智、根本隆行、金井祐、柳田俊彦、和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Heat shock protein 90によるインスリン受容体シグナル分子の発現調節2008
- Author(s)
  吉川教恵, 柳田俊彦, 丸田豊明, 根本隆行, 金井祐, 小林英幸, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リチウムの電位依存性Na^+チャネルに及ぼす影響 : GSK-3β非依存性の機能抑制とGSK-3β依存性の細胞膜発現増加2008
- Author(s)
  柳田俊彦、丸田豊明、根本隆行、上園保仁、松尾清隆、金井祐、宮崎智、和田明彦
- Organizer
  第12回宮崎Neuroscience研究会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 電位依存性Na_v1.7 Na^+チャネルはglycogensynthase kinase-3βを抑制し、tauのリン酸化量を減少させる2008
- Author(s)
  金井祐、柳田俊彦、根本隆行、宮崎智、和田明彦
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Lysophosphatidic acid up-regulated cell surface Na_v1.7 sodium channels in adrenal chromaffin cells2008
- Author(s)
  Maruta T., Yanagita T., Nemoto T., Wada A., Tsuneyoshi I.
- Organizer
  American Society of Anesthesiologists.2008 Annual Meeting
- Place of Presentation
  Orlando, FL., USA
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Na^+チャネル活性はglycogen synthase kinase3βのSer^9リン酸化を制御する : 培養副腎髄質細胞における検討2008
- Author(s)
  金井祐, 柳田俊彦, 根本隆行, 丸田豊明, 吉川教恵, 小林英幸, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 電位依存性Na_v1.7 Na^+チャネル活性によるglycogen synthase kinase-3βの抑制と、tauのリン酸化量の減少2008
- Author(s)
  金井祐、根本隆行、宮崎智、柳田俊彦、和田明彦
- Organizer
  日本薬学会九州支部大会
- Place of Presentation
  延岡市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] ラット脳微少血管に発現しているアグリンの生理機能2008
- Author(s)
  小林英幸, 丸田豊明, 吉川教恵, 根本隆行, 金井祐, 柳田俊彦, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Na^+チャネル活性によるglycogen synthasekinase 3βのSer^9リン酸化の制御2008
- Author(s)
  金井祐、柳田俊彦、根本隆行、丸田豊明、吉川教恵、和田明彦
- Organizer
  第3回トランスポーター研究会年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リゾフォスファチジン酸はLPA_1受容体-Rho-Rho kinaseを介して電位依存性Na_v1.7Na^+チャネルの細胞膜発現量と^<45>Ca^<2+>. Influx・カテコールアミン開口分泌を増加させる2008
- Author(s)
  丸田豊明, 柳田俊彦, 松尾清隆, 上園保仁, 佐藤伸矢, 根本隆行, 吉川教恵, 金井祐, 小林英幸, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Glycogen synthase kinase-3βを介する電位依存性Na^+チャネル細胞膜発現のpositive-feedback regulation2008
- Author(s)
  柳田俊彦, 金井祐, 丸田豊明, 根本隆行, 吉川教恵, 小林英幸, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 抗躁薬リチウムの電位依存性Na^+チャネルに及ぼす影響 : GSK-3β非依存性の機能抑制とGSK-3β依存性の細胞膜発現増加2008
- Author(s)
  柳田俊彦、丸田豊明、上園保仁、松尾清隆、吉川教恵、根本隆行、金井祐、和田明彦
- Organizer
  第3回トランスポーター研究会年会
- Place of Presentation
  京都市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] インスリンシグナルにおけるGSK-3βの役割2008
- Author(s)
  根本隆行, 柳田俊彦, 佐藤伸矢, 丸田豊明, 吉川教恵, 金井祐, 小林英幸, 和田明彦
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Insulin-like growth factor-I受容体発現調節機構の解明2008
- Author(s)
  根本隆行、柳田俊彦、金井祐、宮崎智、和田明彦
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Glycogen synthase kinase-3β活性変動によるprotein kinase B/Aktの発現調節2007
- Author(s)
  根本隆行, 金井祐, 柳田俊彦, 佐藤伸矢, 丸田豊明, 吉川教恵, 小林英幸, 和田明彦
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Heat Shock Protein 90(Hsp90)によるインスリン受容体シグナル分子の発現調節2007
- Author(s)
  吉川教恵, 柳田俊彦, 佐藤伸矢, 根本隆行, 丸田豊明, 金井祐, 横尾宏毅, 小林英幸, 和田明彦
- Organizer
  第11回宮崎Neuroscience研究会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リゾフォスファチジン酸によるNav1.7Na^+チャネルの細胞膜発現量増加2007
- Author(s)
  丸田豊明, 柳田俊彦, 佐藤伸矢, 吉川教恵, 根本隆行, 金井祐, 横尾宏毅, 小林英幸, 和田明彦
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リゾフォスファチジン酸によるNav1.7Na^+チャネルの細胞膜発現量の増加とカテコールアミン開口分泌増強2007
- Author(s)
  丸田豊明, 柳田俊彦, 佐藤伸矢, 吉川教恵, 根本隆行, 金井祐, 横尾宏毅, 小林英幸, 和田明彦
- Organizer
  第35回薬物活性シンポジウム
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リゾフォスファチジン酸(LPA)による電位依存性Na^+チャネル・Nav1.7の細胞膜発現量増加2007
- Author(s)
  丸田豊明, 柳田俊彦, 佐藤伸矢, 吉川教恵, 根本隆行, 金井祐, 横尾宏毅, 小林英幸, 和田明彦
- Organizer
  第11回宮崎Neuroscience研究会
- Place of Presentation
  宮崎市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 免疫抑制薬サイクロスポリンA,FK506によるインスリンシグナリングへの減弱2007
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  第80回宮崎薬理学会年会
- Place of Presentation
  名古屋市
- Year and Date
  2007-03-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] リゾフォスファチジン酸による電位依存性Na^+チャネル機能と細胞膜発現量の変化2007
- Author(s)
  丸田豊明, 柳田俊彦, 松尾清隆, 上園保仁, 和田明彦, 高崎眞弓
- Organizer
  日本麻酔科学会第54回学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] 抗躁薬リチウムによる電位依存性Na^+チャネルの抑制と細胞膜発現量の増加2007
- Author(s)
  柳田俊彦、丸田豊明、上園保仁、松尾清隆、吉川教恵、根本隆行、金井祐、小林英幸、和田明彦
- Organizer
  第1回トランスポーター研究会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] リゾフォスファチジン酸による電位依存性Na^+チャネル機能と細胞膜発現量の変化2007
- Author(s)
  丸田豊明, 柳田俊彦, 松尾清隆, 上園保仁, 佐藤伸矢, 根本隆行, 吉川教恵, 金井祐, 小林英幸, 和田明彦
- Organizer
  第1回トランスポーター研究会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-19500326
[Presentation] Expression of long and short amino terminal forms of agrin in rat cerebral Microvessels2006
- Author(s)
  Kobayashi H, Ynagita T, Yokoo H, Satoh S, Maruta T, Yoshikawa N, Nemoto T, Wada A.
- Organizer
  Society for Neuroxcience 36^<th> Annual Meeting
- Place of Presentation
  Atlanta Georgia, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] Up-and down-rgulation of Isulin receptor signaling molecules by intracellular signals and therapeutic drugs in addenal chromaffin cells2006
- Author(s)
  Satho S, Yanagita T, Sugano T, Nemoto T, Yoshikawa N, Maruta, T, Yokoo H, Kobayashi H, Wada A
- Organizer
  The 21^<st> Century Program 2006 COE International Symposium of University of Miyazaki
- Place of Presentation
  Miyazaki
- Year and Date
  2006-08-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] 神経障害治療薬への新戦略:インスリン受容体シグナル伝達分子の発現調節2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  第115回日本薬理学会関東部会
- Place of Presentation
  群馬県高崎市
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] 免疫抑制薬サイクロスポリンA,FK506によるインスリン/IGF-Iシグナリングへの影響2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  第59回日本薬理学会西南部会
- Place of Presentation
  沖縄県那覇市
- Year and Date
  2006-06-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] Expression of long and short amino terminal forms of agrin in rat cerebral Microvessels.2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  Society for Neuroxcience 36^<th> Annual Meeting
- Place of Presentation
  Atlanta, Georgia, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] Up- and down-regulation of insulin receptor signaling molecules by intracellular signals and therapeutic drugs in addenal chromaffin cells2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  The 21^<st> Century Program 2006 COE International Symposium of University of Miyazaki
- Place of Presentation
  宮崎市
- Year and Date
  2006-08-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875
[Presentation] 免疫抑制薬サイクロスポリンA,FK506によるインスリン/IGF-Iシグナリングへの影響2006
- Author(s)
  佐藤伸矢、和田明彦, 他
- Organizer
  第10回宮崎Neuroscience研究会
- Place of Presentation
  宮崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591875

1. YANAGITA Toshihiko (60295227)

# of Collaborated Projects: 14 results

# of Collaborated Products: 73 results
2. KOBAYASHI Hideyuki (40148953)

# of Collaborated Projects: 13 results

# of Collaborated Products: 7 results
3. YOKOO Hiroki (30332894)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
4. YAMAMOTO Ryuichi (10094111)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
5. TAKARA Hiroshi (30148952)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. UEZONO Yasuhito (20213340)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. SHIGEMATSU Akio (30037428)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. 占部正信 (00094087)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. KITAMURA Kazuo (50204912)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. NEMOTO Takayuki (90506833)

# of Collaborated Projects: 2 results

# of Collaborated Products: 63 results
11. MURAKAMI Manabu (80302090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
12. TOYAMA Katsuhiro (30253834)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWANO Hirokazu (20204745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SATOH Shinya (50468047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
15. MINAMI Shinichi (90448556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 後藤貞夫 (50131917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 池ノ上克 (60232211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 緒方政則 (70169176)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 奥田匠 (60404456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 東野哲也 (80145424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SAKATA Tsuneaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 津藤伸矢

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WADA Akihiko 和田 明彦

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アドレノメデュリンの妊娠子宮・収縮抑制機序:早産治療薬としての基礎研究Principal Investigator

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Voltage-dependent Na+ channel: quality control and stress response.Principal Investigator

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Regulation of cell surface expression of voltage-dependent sodium channels by multiple calcium signalings : their mRNA levels and intracellular traffickingPrincipal Investigator

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Physiological function and gene expression of adremnomedullinfamily : adrenal medullary cells and isolated blood vesselsPrincipal Investigator

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Intracellular mechanisms regulating cell surface expression of Na channels : Na channel subunit mRNA levels and intracellular trafficking.Principal Investigator

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Cカイネースによる細胞膜Naチャネルdown-regulationの細胞内機序Principal Investigator

WADA Akihiko 和田明彦