OHTANI Haruo 大谷明夫

Researcher Number	30133987
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Affiliation (based on the past Project Information) *help	2003: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2001: 東北大学, 大学院・医学系研究所, 助教授 2000 – 2001: 東北大学, 医学部・医学系研究科, 助教授 1999 – 2001: 東北大学, 大学院・医学系研究科, 助教授 1999: Tohoku University School of Medicine Associate Professor, 大学院・医学研究科, 助教授 … More
Review Section/Research Field	Principal Investigator Human pathology / Digestive surgery Except Principal Investigator Digestive surgery / Human pathology / Surgical dentistry / General surgery / Orthopaedic surgery
Keywords	Principal Investigator 大腸癌 / 炎症性腸疾患 / in situ hybridization / MMP-1 / MMP-9 / uPAR / 転移 / リポコルチン-1 / 免疫抑制因子 / 担癌患者 … More Except Principal Investigator 炎症性腸疾患 / 潰瘍性大腸炎 / マクロファージ / 上皮細胞 / VIP / 大腸癌 / 転移 / GFP / 血管新生 / metastasis / angiogenesis / CD44 / 分子生物学 / 粘膜免疫 / 粘膜免疫機構 / 消化管粘膜 / 神経ペプチド / ウロコルチン / 異物反応 / チタニウム / Foreign body reaction / CRF / ulcerative colitis / macrophage / クローン病 / inflammatory bowel disease / FR118487 / Matrix metalloproteinase / B7-2 / 生体顕微鏡 / colorectal cancer / VEGFR-3 / 樹状細胞 / 抗微生物蛋白 / 脳腸ペプチド / vasoactive intestinal peptide(VIP) / VIPレセプター / 免疫組織化学 / 細胞接着分子 / 新生児 / in situ hypridization / ニューロペプチド / サブスタンスP / エンドセリン / Inflammatory bowed disease / Mucosal immunity / Gut hormone / Vasoactive intestinal peptide / VIP receptor / Immunohistochemistry / Cell adhesion molecule / Neonate / 慢性胃炎 / 視床下部 / ステロイドホルモン / 中枢神経系 / 内分泌系 / 消化管悪性腫瘍 / VIP受容体 / アトピー性皮膚炎 / 先天性胆道閉鎖症 / IL-6 / Mucosal immune system / Gastro-intestinal mucosa / Neuropeptide / Inflammatory bowel disease / Chronic gastritis / Macrophage / Hypothalamus / Steroid hormone / 下顎 / TGF-β / 細胞増殖因子 / 線維芽細胞 / Titunium / Mandible / TGF-beta / 神経・内分泌系 / 11β-hydroxy steroid dehydrogenase / 過敏性腸症候群 / 潰瘍大腸炎 / 大腸粘膜 / 胎児 / 11-HDS / 腸管粘膜上皮細胞 / アポトーシス / CRFファミリー / 粘膜炎 / mucosal immune system / neuroendocrine system / 11 β hydroxysteroid dehydrogenase / urocortin / irritable bowel syndrome / クーロン病 / epithelial cell / Ulcerative colitis / germ-free / 血管新生阻害剤 / 骨肉腫 / ラット / 肺転移 / 骨肉腫(osteosarcoma) / 肺転移(lung metostasis) / 血行性転移(Rematogenous metastasis) / 多中心性骨肉腫(multifocal osteosarcoma) / リンパ節転移(lymph node metastacis) / 担癌マウス / マトリックスメタルプロテアーゼ / angiogenesis inhibitor / osteosarcoma / rat / lung metastasis / skin flap / Tissue inhibitor of metalloproteinase / ランゲルハンス細胞 / Skin Flap / Titanium / Tissue inhibitor of matrix metalloroteinase / Langerhans cell / 微小循環 / intravital microscopy / リンパ管新生 / VEGF-C / VEGF-D / 血管内皮前駆細胞 / NOD / SCID / lymphangiogenesis / マイクロアレイ / 腸内細菌 / 無菌 / クローン癌 / intestinal flora / epithelial cells / CRP-ductin / microarray / Crohn's disease / 消化器癌 / 腫瘍増殖 / リンパ節 / 消火器癌 / gastrointestinal cancer / tumor growth / lymph node / 腫瘍免疫 / 樹上細胞 / リンパ球 / フローサイトメトリー / colorectal carcinoma / tumorimmunology / dendritic cell / lymphocyte / flowcytometry / 口腔 / 移植皮膚 / ケモカイン / Oral / Transplanted skin / Chemokine / Dendritic cell Less

Inhibition of tumor growth, invasion, and metastasis by targeting CD44 molecule
- Principal Investigator
  
  MIZOI Takayuki
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  TOHOKU UNIVERSITY
A novel approach to analyze the immunological responses in human colorectal carcinoma
- Principal Investigator
  
  MIZOI Takayuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY
Defense system in the intraorally transplanted skin : the relation between dendritic cells and chemokine system
- Principal Investigator
  
  FUMINORI Katou
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
  Tohoku University
Establishment and Analysis of the in vivo Human Tumor Angiogenesis Model
- Principal Investigator
  
  ISHII Seiichi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Analysis of gene expression associated with inflammatory bowel disease using cDNA microarray
- Principal Investigator
  
  SASAKI Iwao
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
蛋白発現ライブラリーを用いた腸内細菌に対する抗微生物蛋白同定の試み
- Principal Investigator
  
  FUKUSHIMA Kohei
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
Analysis of micromechanisms of metastasis using NOD/SCID-hu and GFP-transfectant human colorectal carcinoma cells
- Principal Investigator
  
  ISHII Seiichi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Tohoku University
Clinicopathological analyses on the blood-borne metastasis in colorectal carcinomaPrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Studies on the regulatory mechanism of immuno-inflammatory responses by the euroendocrine system in the gastrointestinal mucosa, and the mucosal injury by the failure of this regulatory function.
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Identification of Colon-specifi abnormal gene expression in alcerative colitis.
- Principal Investigator
  
  FUKUSHIMA Kouhei
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Tohoku University
The antitumor effect of angiogenesis inhibitor (FR118487) for transplantable rat osteosarcoma with lung metastatic potential
- Principal Investigator
  
  HATORI Masahito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Tohoku University
Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in the encapsulation process against titanium implant
- Principal Investigator
  
  KATOU Fuminori
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tohoku University
In situ expression of matrix-degrading enzymes in inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Expression of TGF-beta in foreign body reaction and fibrosis agaist titanium implant.
- Principal Investigator
  
  KATOU Fuminori
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  TOHOKU UNIVERSITY
癌浸潤に対する炎症性細胞反応とマトリックス分解酵素群の発現の意味の解明Principal Investigator
- Principal Investigator
  
  大谷明夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tohoku University
Closs talk between neuroendocrine and mucosal immune systems in the gastrointestinal mucosa and its disorder
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Possible involvement of vascular cells-related transcription factors in human inflammatory diseases and cancer tissue.Principal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tohoku University
Studies on the neuro-endocrine regulatory mechanism for mucosal immune system
- Principal Investigator
  
  NAGURA Hiroshi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  TOHOKU UNIVERSITY
Analysis of immunosupprative meclauism of Lipocortiut in tuwcr-beurig hestsits expression and action in wanPrincipal Investigator
- Principal Investigator
  
  OHTANI Haruo
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  TOHOKU UNIVERSITY

All 2003 2001

All Journal Article

[Journal Article] Differential expression of CCL 19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamed skin.2003
- Author(s)
  Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  Journal of Pathology 199
  
  Pages: 98-106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Differential expression of CCL19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamad skin.2003
- Author(s)
  Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  J oumal of Pathology 199
  
  Pages: 98-106
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001
- Author(s)
  Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  American Journal of Pathology 158
  
  Pages: 1263-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13672078
[Journal Article] Macrophage-derived chemokine (MDG/CCL22) and CCR4 are involved in the formation of Tlymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001
- Author(s)
  Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
- Journal Title
  
  American J oumal of Pathology 158
  
  Pages: 1263-1270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13672078

1. SASAKI Iwao (60125557)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
2. SHIIBA Ken-ichi (90196345)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. FUKUSHIMA Kohei (20271900)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. SASANO Hironobu (50187142)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. NAGURA Hiroshi (90022821)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. ISHII Seiichi (60221066)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. MIZOI Takayuki (90271949)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. KATOU Fuminori (60204492)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
9. FUNAYAMA Yuji (50192315)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. NAITO Hiroo (90180223)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. KIMURA Noriko (80142975)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
12. SATO Yasufumi (50178779)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. MASUDA Takayuki (00113910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SAITOH Yoshihiro (10215569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. CHIBA Toshio (20171944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SUZUKI Takashi (10261629)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HONGO Michio (60133948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HATORI Masahito (70208552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ISHII Keiko (00291253)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SENBA Shuho (00302092)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KAMEOKA Junichi (30261621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. SAITO Kazuya (30343049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. KATAYOSE Yu (20302151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 樋渡信夫 (00133950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 蝦名宣男 (40185137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. SHIBATA Toshihiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 斎藤一也

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OHTANI Haruo 大谷 明夫

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Clinicopathological analyses on the blood-borne metastasis in colorectal carcinomaPrincipal Investigator

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In situ expression of matrix-degrading enzymes in inflammatory bowel diseasePrincipal Investigator

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癌浸潤に対する炎症性細胞反応とマトリックス分解酵素群の発現の意味の解明Principal Investigator

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OHTANI Haruo 大谷明夫