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OHTANI Haruo  大谷 明夫

ORCIDConnect your ORCID iD *help
Researcher Number 30133987
External Links
Affiliation (based on the past Project Information) *help 2003: Tohoku University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授
2001: 東北大学, 大学院・医学系研究所, 助教授
2000 – 2001: 東北大学, 医学部・医学系研究科, 助教授
1999 – 2001: 東北大学, 大学院・医学系研究科, 助教授
1999: Tohoku University School of Medicine Associate Professor, 大学院・医学研究科, 助教授 … More
1996 – 1999: Tohoku University School of Medicine, Associate Professor, 医学部, 助教授
1997: TOHOKU UNIVERSITY,School of Medicine Associate Professor, 歯学部, 助教授
1995: 東北大学, 医学部, 助手
1992 – 1993: 東北大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Human pathology / Digestive surgery
Except Principal Investigator
Digestive surgery / Human pathology / Surgical dentistry / General surgery / Orthopaedic surgery
Keywords
Principal Investigator
大腸癌 / 炎症性腸疾患 / in situ hybridization / MMP-1 / MMP-9 / uPAR / 転移 / リポコルチン-1 / 免疫抑制因子 / 担癌患者 … More / サプレッサーマクロファージ / Lipocortin-1 / Immunosuppression / Cancer patient / GATA遺伝子 / in situハイブリダイゼーション / GATA-2 / GATA-3 / 癌 / 炎症 / Inflammatory Bowel Disease / Colon cancer / GATA gene / マトリックス分解酵素 / MTI-MMP / マトリックスメタロプロティナーゼ / 組織再構築 / 免疫組織化学 / in situ ハイブリダイゼーション / Inflammatory bowel disease / matrix degradation / MT1-MMP / 癌転移 / 宿主反応 / 免疫反応 / 大腸がん / CD8陽性リンパ球 / 腫瘍免疫 / 多変量解析 / 血行性転移 / マクロファージ / cancer metastasis / Host Reaction / Immune response / Colon Cancer … More
Except Principal Investigator
炎症性腸疾患 / 潰瘍性大腸炎 / マクロファージ / 上皮細胞 / VIP / 大腸癌 / 転移 / GFP / 血管新生 / metastasis / angiogenesis / CD44 / 分子生物学 / 粘膜免疫 / 粘膜免疫機構 / 消化管粘膜 / 神経ペプチド / ウロコルチン / 異物反応 / チタニウム / Foreign body reaction / CRF / ulcerative colitis / macrophage / クローン病 / inflammatory bowel disease / FR118487 / Matrix metalloproteinase / B7-2 / 生体顕微鏡 / colorectal cancer / VEGFR-3 / 樹状細胞 / 抗微生物蛋白 / 脳腸ペプチド / vasoactive intestinal peptide(VIP) / VIPレセプター / 免疫組織化学 / 細胞接着分子 / 新生児 / in situ hypridization / ニューロペプチド / サブスタンスP / エンドセリン / Inflammatory bowed disease / Mucosal immunity / Gut hormone / Vasoactive intestinal peptide / VIP receptor / Immunohistochemistry / Cell adhesion molecule / Neonate / 慢性胃炎 / 視床下部 / ステロイドホルモン / 中枢神経系 / 内分泌系 / 消化管悪性腫瘍 / VIP受容体 / アトピー性皮膚炎 / 先天性胆道閉鎖症 / IL-6 / Mucosal immune system / Gastro-intestinal mucosa / Neuropeptide / Inflammatory bowel disease / Chronic gastritis / Macrophage / Hypothalamus / Steroid hormone / 下顎 / TGF-β / 細胞増殖因子 / 線維芽細胞 / Titunium / Mandible / TGF-beta / 神経・内分泌系 / 11β-hydroxy steroid dehydrogenase / 過敏性腸症候群 / 潰瘍大腸炎 / 大腸粘膜 / 胎児 / 11-HDS / 腸管粘膜上皮細胞 / アポトーシス / CRFファミリー / 粘膜炎 / mucosal immune system / neuroendocrine system / 11 β hydroxysteroid dehydrogenase / urocortin / irritable bowel syndrome / クーロン病 / epithelial cell / Ulcerative colitis / germ-free / 血管新生阻害剤 / 骨肉腫 / ラット / 肺転移 / 骨肉腫(osteosarcoma) / 肺転移(lung metostasis) / 血行性転移(Rematogenous metastasis) / 多中心性骨肉腫(multifocal osteosarcoma) / リンパ節転移(lymph node metastacis) / 担癌マウス / マトリックスメタルプロテアーゼ / angiogenesis inhibitor / osteosarcoma / rat / lung metastasis / skin flap / Tissue inhibitor of metalloproteinase / ランゲルハンス細胞 / Skin Flap / Titanium / Tissue inhibitor of matrix metalloroteinase / Langerhans cell / 微小循環 / intravital microscopy / リンパ管新生 / VEGF-C / VEGF-D / 血管内皮前駆細胞 / NOD / SCID / lymphangiogenesis / マイクロアレイ / 腸内細菌 / 無菌 / クローン癌 / intestinal flora / epithelial cells / CRP-ductin / microarray / Crohn's disease / 消化器癌 / 腫瘍増殖 / リンパ節 / 消火器癌 / gastrointestinal cancer / tumor growth / lymph node / 腫瘍免疫 / 樹上細胞 / リンパ球 / フローサイトメトリー / colorectal carcinoma / tumorimmunology / dendritic cell / lymphocyte / flowcytometry / 口腔 / 移植皮膚 / ケモカイン / Oral / Transplanted skin / Chemokine / Dendritic cell Less
  • Research Projects

    (19 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (28 People)
  •  Inhibition of tumor growth, invasion, and metastasis by targeting CD44 molecule

    • Principal Investigator
      MIZOI Takayuki
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  A novel approach to analyze the immunological responses in human colorectal carcinoma

    • Principal Investigator
      MIZOI Takayuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY
  •  Defense system in the intraorally transplanted skin : the relation between dendritic cells and chemokine system

    • Principal Investigator
      FUMINORI Katou
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE
      Tohoku University
  •  Establishment and Analysis of the in vivo Human Tumor Angiogenesis Model

    • Principal Investigator
      ISHII Seiichi
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Analysis of gene expression associated with inflammatory bowel disease using cDNA microarray

    • Principal Investigator
      SASAKI Iwao
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  蛋白発現ライブラリーを用いた腸内細菌に対する抗微生物蛋白同定の試み

    • Principal Investigator
      FUKUSHIMA Kohei
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  Analysis of micromechanisms of metastasis using NOD/SCID-hu and GFP-transfectant human colorectal carcinoma cells

    • Principal Investigator
      ISHII Seiichi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Tohoku University
  •  Clinicopathological analyses on the blood-borne metastasis in colorectal carcinomaPrincipal Investigator

    • Principal Investigator
      OHTANI Haruo
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  Studies on the regulatory mechanism of immuno-inflammatory responses by the euroendocrine system in the gastrointestinal mucosa, and the mucosal injury by the failure of this regulatory function.

    • Principal Investigator
      NAGURA Hiroshi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  Identification of Colon-specifi abnormal gene expression in alcerative colitis.

    • Principal Investigator
      FUKUSHIMA Kouhei
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Tohoku University
  •  The antitumor effect of angiogenesis inhibitor (FR118487) for transplantable rat osteosarcoma with lung metastatic potential

    • Principal Investigator
      HATORI Masahito
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tohoku University
  •  Expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinase in the encapsulation process against titanium implant

    • Principal Investigator
      KATOU Fuminori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      Tohoku University
  •  In situ expression of matrix-degrading enzymes in inflammatory bowel diseasePrincipal Investigator

    • Principal Investigator
      OHTANI Haruo
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  Expression of TGF-beta in foreign body reaction and fibrosis agaist titanium implant.

    • Principal Investigator
      KATOU Fuminori
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Surgical dentistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  癌浸潤に対する炎症性細胞反応とマトリックス分解酵素群の発現の意味の解明Principal Investigator

    • Principal Investigator
      大谷 明夫
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  Closs talk between neuroendocrine and mucosal immune systems in the gastrointestinal mucosa and its disorder

    • Principal Investigator
      NAGURA Hiroshi
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  Possible involvement of vascular cells-related transcription factors in human inflammatory diseases and cancer tissue.Principal Investigator

    • Principal Investigator
      OHTANI Haruo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Tohoku University
  •  Studies on the neuro-endocrine regulatory mechanism for mucosal immune system

    • Principal Investigator
      NAGURA Hiroshi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Analysis of immunosupprative meclauism of Lipocortiut in tuwcr-beurig hestsits expression and action in wanPrincipal Investigator

    • Principal Investigator
      OHTANI Haruo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      TOHOKU UNIVERSITY

All 2003 2001

All Journal Article

  • [Journal Article] Differential expression of CCL 19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamed skin.2003

    • Author(s)
      Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
    • Journal Title

      Journal of Pathology 199

      Pages: 98-106

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13672078
  • [Journal Article] Differential expression of CCL19 by DC-Lamp+ mature dendritic cells in human lymph node versus chronically inflamad skin.2003

    • Author(s)
      Katou F, Ohtani H, Nakayama T, Nagura H, Yoshie O, Motegi K.
    • Journal Title

      J oumal of Pathology 199

      Pages: 98-106

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13672078
  • [Journal Article] Macrophage-derived chemokine (MDC/CCL22) and CCR4 are involved in the formation of T lymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001

    • Author(s)
      Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
    • Journal Title

      American Journal of Pathology 158

      Pages: 1263-70

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13672078
  • [Journal Article] Macrophage-derived chemokine (MDG/CCL22) and CCR4 are involved in the formation of Tlymphocyte-dendritic cell clusters in human inflamed skin and secondary lymphoid tissue.2001

    • Author(s)
      Katou F, Ohtani H, Nakayama T, Ono K, Matsushima K, Saaristo A, Nagura H, Yoshie O, Motegi K.
    • Journal Title

      American J oumal of Pathology 158

      Pages: 1263-1270

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13672078
  • 1.  SASAKI Iwao (60125557)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 2.  SHIIBA Ken-ichi (90196345)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  FUKUSHIMA Kohei (20271900)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  SASANO Hironobu (50187142)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  NAGURA Hiroshi (90022821)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  ISHII Seiichi (60221066)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  MIZOI Takayuki (90271949)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  KATOU Fuminori (60204492)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 9.  FUNAYAMA Yuji (50192315)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  NAITO Hiroo (90180223)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  KIMURA Noriko (80142975)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  SATO Yasufumi (50178779)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  MASUDA Takayuki (00113910)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SAITOH Yoshihiro (10215569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  CHIBA Toshio (20171944)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YAMAMOTO Masayuki (50166823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  SUZUKI Takashi (10261629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HONGO Michio (60133948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  HATORI Masahito (70208552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  ISHII Keiko (00291253)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SENBA Shuho (00302092)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  KAMEOKA Junichi (30261621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  SAITO Kazuya (30343049)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  KATAYOSE Yu (20302151)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  樋渡 信夫 (00133950)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  蝦名 宣男 (40185137)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SHIBATA Toshihiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  斎藤 一也
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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