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TAKADA Haruhiko  高田 春比古

ORCIDConnect your ORCID iD *help
Researcher Number 30135743
External Links
Affiliation (based on the past Project Information) *help 2013 – 2014: 東北大学, 歯学研究科(研究院), 教授
2007 – 2008: Tohoku University, 大学院・歯学研究科, 教授
2007: Tohoku University, Graduate School of Dentistry, Professor
2006: 東北大学, 大学院歯学研究科, 教授
2000 – 2005: Tohoku University, Graduate School of Dentistry, Professor, 大学院・歯学研究科, 教授 … More
1996 – 2000: 東北大学, 歯学部, 教授
1992 – 1995: 鹿児島大学, 歯学部, 教授
1990: Osaka Univ. Facul. Dent., Assistant Prof., 歯学部, 助教授
1990: 鹿児島大学, 歯学部, 教授
1986 – 1989: 大阪大学, 歯学部, 講師
1986: 阪大, 歯学部, 講師 Less
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Morphological basic dentistry / 細菌学 / 病態科学系歯学(含放射線系歯学) / Functional basic dentistry / Pathobiological dentistry/Dental radiology / Applied microbiology
Except Principal Investigator
Morphological basic dentistry / Conservative dentistry / 小児・社会系歯学 … More / Functional basic dentistry / 細菌学 / Morphological basic dentistry / Bacteriology (including Mycology) / 病態科学系歯学(含放射線系歯学) Less
Keywords
Principal Investigator
NOD2 / 上皮細胞 / LPS / Toll-like receptor / CD14 / 自然免疫 / 線維芽細胞 / ペプチドグリカン / NOD1 / Innate immunity … More / 口腔レンサ球菌 / ジンジパイン / 口腔上皮細胞 / レクチン経路 / 血小板 / リポタイコ酸 / Streptococcus sanguis / ICAM-1 / Streptococcus mitis / 腫瘍壊死因子 / Bacteroides / Staphylococcus aureus / Streptococcus faecalis / PGRP / NOD-2 / NOD-1 / Toll-like receptor(TLR) / デフェンシン / PGRPs / Oral epithelial cells / Protease-activated receptor / Peptidoglycan / MDP / MyD88 / Prevotella intermedia / 歯肉線維芽細胞 / SPM / Streptococcus pyogenes / リピドA / 口腔粘膜 / プロバイオテイクス / Toll-like receptors / 補体 / スーパー抗原 / 内毒素 / サイトカインネットワ-ク / リポ多糖 / Bacterial components / Cell fusion / Protoplast / L-Form / 復帰培地 / 生物活性 / 菌体成分 / Staphylococcusaureus / 細胞融合 / プロトプラスト / L型菌 / Inflammatory response / Peptidoglycan recognition protein (PGRP) / β-Defensin 2 / Toll-like receptor (TLR / Porphyromonas gingivalis / デイフェンシン / 炎症応答 / ペプチドグリカン認識蛋白(PGRP) / β-2デイフェンシン / Toll-like receptor (TLR) / Epithelial cells / Defensins / Toll-like receptors (TLRs) / リポペプチド / Toll-like receptors(TLRs) / Gingipain / Human gingival fibroblasts / 歯肉繊維芽細胞 / Muramyldipeptide / Lipoteichoic acid / ペプチドグライカン / ムラミルジペプチド / gingival fibroblasts / peptidoglycan / lipoteichoic acid / 歯周病 / 歯髄細胞 / IL-8 / Streptococcus mutans / T cells / epithelial cells / superantigen / Oral streptococci / UFA-1 / Streptococons mitis / ビリダンスレンサ球菌 / CPA / SEB / S.pyogenes / 口腔粘膜疾患 / T細胞 / インターロイキシ6 / インターフェロン / BRM / ムラミルペプチド / サイトカイン / マウス / ビタミンD類 / LL-37 / 抗菌因子 / 植物寄生性乳酸菌 / Lactobacillus plantarum / 免疫増強 / 粘膜免疫 / Lactobacillus / mannose-binding lectin / マンノース・ホモポリマー / アナフィラキシー様ショック / Candida albicans / マンノースホモポリマー / アナフィラキシー様反応 / スキャッターファクター / インターロイキン-1 / 肝細胞増殖因子 / HLA-DR / 細胞障害作用 / リムラス活性 / インターロイキン-6 / マイトジェン / Bacteroides intermedius / IFNーβ / IL6 / IL1β / IL1α / インタ-フェロン / インタ-ロイキンー6 / インタ-ロイキンー1 … More
Except Principal Investigator
CD14 / サイトカイン / 歯周病 / LPS / cytokines / う蝕 / Streptococcus mutans / 線毛 / IgG / Bacteroides gingivalis / ラテックス凝集反応 / S.mutans / innate immunity / プロテアーゼ活性化受容体 / 自然免疫 / periodontitis / リポタイコ酸 / IL-6 / TNF / Dental caries / Fimbriae / Periodontal disease / 抗体 / 菌体成分 / ムラミルジペプチド / Bacteroides / Antibody / Latex agglutination / ポリクロナール抗体 / モノクロナール抗体 / ラテックス凝集法 / Ltex beads / Monoclonal antibodies / Dental caties / 抗原抗体反応 / 凝集反応 / 診断キット / モノクローン抗体 / Gene cloning / Protein antigen / mutans / S / バクテリオシン / IgAプロテアーゼ / プラスミド / DNA / S.sanguis / S, mutans / S、mutans / 付着 / 遺伝子クローニング / タンパク抗原 / muramyl dipeptide / invasion / colonization / fimbriae / Virulence / Cell surface / 生理活性物質 / ミコール酸 / α毒素 / 侵入因子 / 表層構造 / 付着因子 / 侵入性 / MDP / Lps / モノクローナル抗体 / 細胞壁タンパク / 紋毛 / 定着因子 / oral mucosa / protease-activated receptors / proteases / neutrophils / periodontopathic bacteria / 血小板 / 口腔粘膜 / プロテアーゼ / 好中球 / 歯周病原菌 / neutrophil proteinases / saliva / fibroblasts / mucosal immunity / oral epithelial cells / 好中球プロテアーゼ / 唾液 / 線維芽細胞 / 粘膜免疫 / 口腔上皮細胞 / proinflammatory cytokine / NF-kB / SSRE / stretch force / periodontal ligament cells / 増殖因子 / メカニカルストレス / 歯周炎 / 咬合性外傷 / 炎症性サイトカイン / NF-κβ / ストレッチ負荷応答配列 / ストレッチ / 歯根膜細胞 / Toll-like receptors / antagonist / endotoxin / lipoteichoic acids / oral streptococci / Toll-like receptor / アンタゴニスト作用 / エンドトキシン / 口腔レンサ球菌 / activation mechanism / adhesion molecules / human gingival epithelial cells / black-pigmented bacteria / 活性化機構 / 接着分子 / 歯肉上皮細胞 / 黒色色素産生菌 / Oral anaerbers / 根管内細菌 / Egg yolk antibody / Oral passive immunization / Glucosyltransferase / 受動免疫 / Stroptococcus mutans / 卵黄抗体 / 経口受動免疫 / グルコシルトランスフェラ-ゼ / Adjuvant / Cytokine / Local Immunity / Immunoglobulin / Porphyromanas gingivalis / Hー2ハプロタイプ / サブクラス / クラス / 線毛タンパク / 免疫応答 / ELISPOT / ELISA / 抗体産生細胞 / アジュバント / 局所免疫 / 免疫グロブリン / Porphyromonas gingivalis / DNAポリメラーゼα / Thymidine kinase / A kinase / DNA合成抑制 / 細菌細胞壁ペプチドグリカン / リポポリサッカライド / マクロファージ / 遅延型過敏症 / 壊死性潰瘍性歯肉炎 / 免疫抑制剤 / 腫瘍壊死因子 / 出血壊死反応 / リポ多糖 Less
  • Research Projects

    (31 results)
  • Research Products

    (175 results)
  • Co-Researchers

    (42 People)
  •  Commensalism with oral streotococci: Up-regulation of innate immunityPrincipal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Tohoku University
  •  植物寄生性LactobacillusによるNOD1活性化と消化管粘膜自然免疫増強Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Applied microbiology
    • Research Institution
      Tohoku University
  •  Innate immune system in oral mucosa, with special reference to inhibition of inflammatory and immune responses and up-regulation of antibacterial functionsPrincipal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Innate Immune Response via Intracellular Receptor NODs and Periodontal DiseasesPrincipal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  Novel bioactivities of neutrophil serine proteases against periodontopathic bacteria in innate immunity

    • Principal Investigator
      SUGAWARA Shunji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Periodontal Diseases as a Hypersensitivity Reaction Based on Innate Immune Responses in Periodontal TissuesPrincipal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Regulation of oral mucosal immunity in human oral epithelial cells and periodontitis

    • Principal Investigator
      SUGAWARA Shunji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Candida albicansによるアナフィラキシー様急性炎症の惹起-細胞壁マンナンによるレクチン経路を介する補体活性化の可能性-Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tohoku University
  •  Recognition of Cell-Surface Components of Bacteria in Innate Immune System, with Special Reference to the Role of Toll-Like ReceptorsPrincipal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Analysis of endotoxin antagonism of lipoteichoic acids from oral streptococci

    • Principal Investigator
      SUGAWARA Shunji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Analysis of new transcription factors induced by stretch force in periodontal ligament cells

    • Principal Investigator
      MATSUSHITA Kenji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kagoshima University
  •  黒色色素産生菌LPSによるアナフィラキシー様急性炎症の惹起Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Tohoku University
  •  Bacterial cell surface amphiphiles and periodontal diseases - Study on the role of CD14 molecule in periodontal tissues -Principal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      TOHOKU UNIVERSITY
  •  Activation of human gingival epithelial cells by black-pigmented bacteria

    • Principal Investigator
      SUGAWARA Shunji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  Superantigen Produced by oral Streptococci and oral mucosal diseases.Principal Investigator

    • Principal Investigator
      TAKADA Haruhiko
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Tohoku University
  •  口腔レンサ球菌のリポタイコ酸の免疫・生物学的活性Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kagoshima University
  •  MDPレセプターと細胞内シグナル伝達機構

    • Principal Investigator
      永尾 重喜
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      Kagoshima University
  •  口腔レンサ球菌の産生するスーパー抗原の免疫・病理活性Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kagoshima University
  •  Bacteroides LPSに特有の生物活性を担う構造の探究Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kagoshima University
  •  口腔Bacteroidesとムラミルジペプチドによる出血・壊死反応の解析

    • Principal Investigator
      永尾 重喜
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kagoshima University
  •  Cytokine induetion in severe periapical pathosis by oral anaerobes

    • Principal Investigator
      KAWAGOE Masataka
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Kagoshima University
  •  局所炎症・免疫反応のレギュレ-タ-としての線維芽細胞Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Kagoshima University
  •  ヒト歯肉線維芽細胞を廻るサイトカインネットワ-クPrincipal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  Studies on the pathogenesis of periodontal disease from the viewpoint of local immunity

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  Development of Passive Immunization System Against Dental Caries by Hen Egg Yolk Antibodies of Streptococcus Mutans.

    • Principal Investigator
      OOSHIMA Takashi
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B).
    • Research Field
      小児・社会系歯学
    • Research Institution
      Osaka University Faculty of Dentistry
  •  合成ムラミルペプチドによる低毒性リピドA類縁体の生体反応調節(BRM)作用の増強Principal Investigator

    • Principal Investigator
      高田 春比古
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Osaka University
  •  DEVELOPMENT OF LATEX AGGLUTINATION TEST FOR SPECIFIC DETECTION OF BACTEROIDES GINGIVALIS

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Conservative dentistry
    • Research Institution
      OSAKA UNIVERSITY
  •  Gene Cloning of Virulence Factors of Streptococcus mutans

    • Principal Investigator
      HAMADA Shigeyuki
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  Studies on cell fusion between various combinations of L-forms and protoplasts of bacteria.Principal Investigator

    • Principal Investigator
      TAKADA Hariuhiko
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      細菌学
    • Research Institution
      Osaka University
  •  Rapid Method for Identification of S. mutans from Human Clinical Specimens Using Monospecific Antibodies

    • Principal Investigator
      HAMADA Shigeyyki
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      小児・社会系歯学
    • Research Institution
      Osaka University
  •  The group studies on the structural and functional roles of the bacterial surfaces in the infections.

    • Principal Investigator
      AMAKO Kazunobu
    • Project Period (FY)
      1985 – 1987
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      細菌学
    • Research Institution
      Kyushu University

All 2015 2014 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] Interface Oral Health Science 2014.2015

    • Author(s)
      Tada H, Shimauchi H, Takada H, Matsushita K (分担執筆)   (編者:Sasaki K, Suzuki O, Takahashi N)
    • Total Pages
      351
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25670794
  • [Book] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Expression of various Toll-like receptors, NOD1, and NOD2, in human oral epithelial cells, and their function2007

    • Author(s)
      Sugawara, Y., A. Uehara, Y. Fujimoto, K. Fukase, Sasano, and H. Takada.
    • Publisher
      Springer, Tokyo
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] Expression of various Toll-like receptors, NOD1, and NOD2, in human oral epithelial cells, and their function, In M. Watanabe & O. Okuno (ed.) Interface Oral Health Science 20072007

    • Author(s)
      Sugawara, Y., A. Uehara, Y. Fujimoto, K. Fukase, T. Sasano, and H. Takada.
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] エンドトキシン研究10-基礎と臨床の最新知見-: 日本エンドトキシン研究会(上西 紀夫 小川利久 小玉正智 横地高志 谷 徹)編分担: 抗PR3抗体はPAR-2を介してヒト単球系細胞の各種TLR系およびNOD系発現を高めて自然免疫応答を増強する2007

    • Author(s)
      上原亜希子, 高田春比古
    • Publisher
      医学図書出版、東京
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] An antibacterial protein CAP18/LL-37 enhanced production of hepatocyte growh factor in human gingival fibroblast cultures, In M. Watanabe & O. Okuno (ed.) Interface Oral Health Science 20072007

    • Author(s)
      Maeda, H., A. Uehara, T. Saito, H. Mayanagi, I. Nagaoka, and H. Takada
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] Priming effects of microbial or inflammatory agents in metal allergy, In M. Watanabe & O. Okuno (ed.) Interface Oral Health Science 20072007

    • Author(s)
      Sato, N., M. Kinbara, T. Kuroishi, H. Takada, K. Kimura, S. Sugawara, and Y. Endo.
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] Antibodies against protease 3 prime human monocytic cells in culture in a protease-activated receptor 2-and NF-κB-dependent manner for various Toll-like receptor-, NOD1-, and NOD2-mediated activation ,In M. Watanabe & O. Okuno (ed.) Interface Oral Health Science 20072007

    • Author(s)
      Uehara, A., T. Sato, S. Yokota, A. Iwashiro, and H. Takada.
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] Meso-diaminopimelic acid meso-Ianthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD1, In M. Watanabe & O. Okuno (ed.) Interface Oral Health Science 20072007

    • Author(s)
      Uehara, A., T. Sato, S. Yokota, A. Iwashiro, and H. Takada.
    • Publisher
      Springer, Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] エンドトキシン研究 9 : 自然免疫の最前線(熊沢義雄他編)2006

    • Author(s)
      上原亜希子, 菅原由美子, 藤本ゆかり, 楠本正一, 深瀬浩一, 山口高弘, 柴田健一郎, 高田春比古
    • Publisher
      医学図書出版株式会社(東京)
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Book] Effects of muramyl dipeptide on osteoclast formation induced by LPS, IL-1 and TNF-α in mouse culture system.(In : M. Watanabe, N. Takahashi, and H. Takada (eds))(Interface Oral Health Science(International Congress Series 1284))2005

    • Author(s)
      Yang S, Takahashi N, Tkahashi M, Takada H, Furusawa K, Udagawa N(分担執筆)
    • Publisher
      Elsevier, Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Higher induction of histamine-forming enzyme, histidine decarboxylase, in various tissues in muramyldipeptide- and desmuramylpeptide-primed mice following intravenous injection of endotoxin.(In : M. Watanabe, N. Takahashi, and H. Takada (eds))(Interface Oral Health Science (International Congress Series 1284))2005

    • Author(s)
      Funayama H, Huang L, Hagiwara M, Endo Y, Takada H(分担執筆)
    • Publisher
      Elsevier, Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Annual Review 免疫 2006 分担:ペプチドグリカンの構造と宿主免疫応答2005

    • Author(s)
      奥村 康, 平野俊夫, 佐藤昇志(編) 分担:上原亜希子, 高田春比古
    • Publisher
      中外医学社, 東京
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Upregulation of PGRPs by chemically synthesized pathogen-associated molecular patterns via Toll-like receptors, NOD1 and NOD2 in oral epithelial cells.(In : M. Watanabe, N. Takahashi, and H. Takada (eds))(Interface Oral Health Science (International Congress Series 1284))2005

    • Author(s)
      Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Sasano T, Shibata K, Sugawara S, Takada H(分担執筆)
    • Publisher
      Elsevier, Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] 口腔微生物学・免疫学 第2版 分担:免疫学の基礎2005

    • Author(s)
      浜田茂幸 編 分担:菅原俊二, 高田春比古
    • Publisher
      医歯薬出版, 東京
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Interface Oral Health Science (International Congress Series 1284) Endogenous membrane-bound IL-15 sustains recruitment of IL-2Rβ and common γ through activation of NF-κB in human gingival fibroblasts.2005

    • Author(s)
      Watanabe M, Takahashi N, Takada H(ed), Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] エンドトキシン研究8 その新たな展開 分担:マウスにおけるエンドトキシン刺激によるヒスタミン合成酵素histidine decarboxylase(HDC)活性の誘導:合成NOD系リガンド前投与による増強2005

    • Author(s)
      日本エンドトキシン研究会(吉川敏一, 小玉正智, 横地高志, 谷 徹)編 分担:船山ひろみ, 黄 玲, 遠藤康男, 高田春比古
    • Publisher
      医学図書出版, 東京
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Interface Oral Health Science (International Congress Series 1284) Upregulation of PGRPs by chemically synthesized pathogen-associated molecular patterns via Toll-like receptors, NOD1 and NOD2 in oral epithelial cells.2005

    • Author(s)
      Watanabe M, Takahashi N, Takada H(ed), Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Sasano T, Shibata K, Sugawara S, Takada H
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] 岩垂育英会創立40周年記念誌 分担:宿主の細菌認識機構と口腔粘膜の自然免疫-特にペプチドグリカン認識機構-2005

    • Author(s)
      石田 甫 編 分担:高田春比古
    • Publisher
      財団法人岩垂育英会, 大阪
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Endogenous membrane-bound IL-15 sustains recruitment of IL-2Rβ and common γ through activation of NF-κB in human gingival fibroblasts.(In : M. Watanabe, N. Takahashi, and H. Takada (eds))(Interface Oral Health Science (International Congress Series 1284))2005

    • Author(s)
      Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S(分担執筆)
    • Publisher
      Elsevier, Amsterdam
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] エンドトキシン研究8 その新たな展開 分担:自然免疫系の細菌認識におけるNOD系とTLR系刺激の相乗作用2005

    • Author(s)
      日本エンドトキシン研究会(吉川敏一, 小玉正智, 横地高志, 谷 徹)編 分担:上原亜希子, 藤本ゆかり, 深瀬浩一, 楠本正一, 柴田健一郎, 菅原俊二, 高田春比古
    • Publisher
      医学図書出版, 東京
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Interface Oral Health Science (International Congress Series 1284) Higher induction of histamine-forming enzyme, histidine decarboxylase, in various tissues in muramyldipeptide- and desmuramylpeptide-primed mice following intravenous injection of endotoxin.2005

    • Author(s)
      Watanabe M, Takahashi N, Takada H(ed), Funayama H, Huang L, Hagiwara M, Endo Y, Takada H
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Book] Interface Oral Health Science (International Congress Series 1284) Effects of muramyl dipeptide on osteoclast formation induced by LPS, IL-1 and TNF-α in mouse culture system.2005

    • Author(s)
      Watanabe M, Takahashi N, Takada H(ed), Yang S, Takahashi N, Takahashi M, Takada H, Furusawa K, Udagawa N
    • Publisher
      Elsevier, Amsterdam
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Molecular cloning and functional characterization of procine nucleotide-binding oligomerization domani-2(NOD2)2008

    • Author(s)
      Tohno, M., W. Ueda, Y. Azuma, T. Shimazu, S. Katoh, J. M. Wang, H. Aso, H. Takada, Y. Kawai, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 194-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1(NOD1)recognizing minmum agonists, meso-diaminopimelic acid amd meso-lanthionine.2008

    • Author(s)
      Tohno, M., T. Shimazu, H. Aso, A. Uehara, H. Takada, A. Kawasaki, Y. Fujimoto, K. Fukase, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 1808-1817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Synergism between TLRs and NOD1/2 in oral epithelial cells.2008

    • Author(s)
      Uehara, A., and H. Takada.
    • Journal Title

      Journal of Dental Research (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Expression of functional Toll-like receptors and nucleotide-binding oligo-merization domain proteins in murine cemento-blasts and their upregula-tionm during cell differentiation2008

    • Author(s)
      Nemoto E, Honda T, Kanaya S, Takada H, Shimauchi H
    • Journal Title

      J Periodontt Res 43

      Pages: 585-593

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine.2008

    • Author(s)
      Tohno, M., T. Shimazu, H. Aso, A. Uehara, H. Takada, A, Kawasaki, Y. Fujimoto, K. Fukase, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 1807-1817

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells2008

    • Author(s)
      Uehara A, Imamura T, Potempa J, Travis J, Takada H
    • Journal Title

      Cell Microbiol 10

      Pages: 1181-1189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Antibodies to protease 3 prime human oral, lung, and kidney epithelial cells to secrete proinflammatory cytokines upon stimulation with ago-niststo various Toll-like receptors, NOD1, and NOD22008

    • Author(s)
      Uehara A, Hirabayashi, Takada H
    • Journal Title

      Clin Vaccine Immunol 15

      Pages: 1060-1066

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] A polymer-type water-soluble peptidoglycan exhibited bith Toll-like recep-tor 2- and NOD2-agonistic activities, resulting in synergistic activation of human monocytic cells2008

    • Author(s)
      Natsuka M, Uehara A, Yang S, Echigo S, Takada H
    • Journal Title

      Innate Immunity 14

      Pages: 298-308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Dual regulation of interleukin-8 production in human oral epiehelial cells upon stimulation with gingipains from Porphyromonas gingivalis2008

    • Author(s)
      Uehara A, Naito M, Imamura T, Potempa J, Travis J, Nakayama K, Takada H
    • Journal Title

      J Med Microbiol 57

      Pages: 500-507

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-2(NOD2).2008

    • Author(s)
      Tohno, M., W. Ueda, Y. Azuma, T. Shimazu, S. Katoh, J. M. Wang, H. Aso, H. Takada, Y. Kawai, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 194-203

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Gingipains from Porphyromonas gingivalis synergistically induce the production of proinflammatory cytokines through protease-activated receptors with Toll-like receptor and NOD1/2 ligands in human monocytic cells.2008

    • Author(s)
      Uehara, A., T. Imamura, J. Potempa, J. Travis, and H. Takada.
    • Journal Title

      Cellular Microbiology (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Synergism between TLRs and NOD1/2 in oral epithelial cells2008

    • Author(s)
      Uehara A, Takada H
    • Journal Title

      J Dent Res 87

      Pages: 682-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Autophagic control of listeria through intracellular innate immune recognition in drosophila2008

    • Author(s)
      Yano T, Mita S, Ohmori H, Oshima Y, Fujimoto Y, Ueda R, Takada H, Goldman WE, Fukase K, Silverman N, Yoshimori T, Kurata S
    • Journal Title

      Nat Immunol 9

      Pages: 908-916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Dual regulation of interleukin-8 production in human oral epithelial cells upon stimulation with gingipains from porphyromonas gingi-valis.2008

    • Author(s)
      Uehara, A., M. Naito, T. Imamura, J. Potempa, J. Travis, K. Nakayama, and H. Takada.
    • Journal Title

      Journal of Medical Microbioogy. 57

      Pages: 500-507

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-2 (NOD2).2008

    • Author(s)
      Tohno, M., W. Ueda, Y. Azuma, T. Shimazu, S. Katoh, J.M. Wang, H. Aso, H. Takada, Y. Kawai, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 194-203

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Synergism between TLRs and NOD1/2 in oral epithelial cells.2008

    • Author(s)
      Uehara, A., and H. Takada.
    • Journal Title

      Journal of Dental Research (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-1(NOD1)recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine.2008

    • Author(s)
      Tohno, M., T. Shimazu, H. Aso, A, Uehara, H. Takada, A. Kawasaki, Y. Fujimoto, K. Fukase, T. Saito, H. Kitazawa.
    • Journal Title

      Molecular Immunology 45

      Pages: 1808-1817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-2 (NOD2)2008

    • Author(s)
      Tohno, M., W. Ueda, Y. Azuma, T. Shimazu, S. Katoh, J.M. Wang, H. Aso, H. Takada. Y. Kawai, T. Saito, H. Kitazawa.
    • Journal Title

      Mol. Immunol 45-1

      Pages: 194-203

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Molecular cloning and functional characterization of porcine nuckeotide-binding oligomerization domain-1 (NOD1) recognizing minimum agonists, meso-diaminopimelic acid and meso-lanthionine2008

    • Author(s)
      Tohno, M., T. Shimazu, H. Aso, A. Uehara. H. Takada. A. Kawasaki, Y. Fujimoto, K. Fukase, T. Saito, H. Kitazawa.
    • Journal Title

      Mol. Immunol 45-6

      Pages: 1807-1817

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Functional TLRs and NODs in human gingival fibroblasts.2007

    • Author(s)
      Uehara A, Takada H
    • Journal Title

      Journal of Dental Research 86・3

      Pages: 249-254

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-κB for Toll-like recepor- and NOD-dependent activation2007

    • Author(s)
      Uehara. A., A. Iwashiro, T. Sato, S. Yokota, and H. Takada.
    • Journal Title

      Mol Immunol 44-14

      Pages: 3552-3562

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines2007

    • Author(s)
      Uehara. A.. Y. Fujimoto, K. Fukase, and H. Takada.
    • Journal Title

      Mol. Immunol 44-12

      Pages: 3100-3111

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Oral bacterial lipopolysaccharide acts in mice to promote sensitisation to ovalbumin and to augment anaphylaxis via platelets2007

    • Author(s)
      Yoshida, A., X. Deng, T. Sasano, H. Takada. S. Sugawara, and Y. Endo.
    • Journal Title

      Arch. Oral Biol 52-10

      Pages: 990-994

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Antibodies against protease 3 prime human monocytic cells in culture in a protease-activated receptor 2- and NF-κB-dependent manner for various Toll-like receptor-, NOD1-, and NOD2-mediated activation2007

    • Author(s)
      Uehara. A.. T. Sato, S. Yokota, A Iwashiro, and H. Takada.
    • Journal Title

      Interface Oral Health Science (M. Watanabe & O. Okuno (ed.)) (Springer, Tokyo)

      Pages: 237-242

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-κB for Toll-like recepor- andNOD-dependent activation.2007

    • Author(s)
      Uehara, A., A. Iwashiro, T. Sato, S. Yokota, and H. Takada.
    • Journal Title

      Molecular Immunology 44

      Pages: 3552-3562

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: An antibacterial protein CAP18/LL-37 enhanced production of hepatocyte growth factor2007

    • Author(s)
      Maeda, H., A. Uehara, T. Saito, H. Mayanagi, I. Nagaoka, and H. Takada.
    • Journal Title

      Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: An antibacterial protein CAP18/LL-37 enhanced production of hepatocyte growth factor in human gingival fibroblast cultures, Springer, Tokyo

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Functional TLRs and NODs in human gingival fibroblasts2007

    • Author(s)
      Uehara. A., and H. Takada.
    • Journal Title

      J. Dent. Res 86-3

      Pages: 249-254

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-κB for Toll-like recepor-and NOD-depent activation.2007

    • Author(s)
      Uehara, A., A. Iwashiro, T. Sato, S. Yokota, and H. Takada.
    • Journal Title

      Molecular Immunology 44

      Pages: 3552-3562

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Priming effects of microbial or inflammatory agents in metal allergy2007

    • Author(s)
      Sato, N., M. Kinbara, T. Kuroishi, H. Takada. K. Kimura, S. Sugawara, and Y. Endo.
    • Journal Title

      Interface Oral Health Science (M. Watanabe & O. Okuno (ed.)) (Springer, Tokyo)

      Pages: 297-298

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] 口腔細菌と歯周病 : 口腔粘膜の自然免疫系2007

    • Author(s)
      上原亜希子, 高田春比古
    • Journal Title

      CLINICAL CALCIUM 17・2

      Pages: 173-178

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines.2007

    • Author(s)
      Uehara, A., Y. Fujimoto, K. Fukase, and H. Takada.
    • Journal Title

      Molecular Immunology 44

      Pages: 3200-3111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Antibodies against protease 3 prime human monocytic cells2007

    • Author(s)
      Uehara, A., T. Sato, S. Yokota, A. Iwashiro, and H. Takada.
    • Journal Title

      Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Antibodies against protease 3 prime human monocytic cells in culture in a protease-activated receptor 2-and NF-κB-dependent manner for various Toll-like recep-tor-, NOD1-, and NOD2-mediate

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Expression of various Toll-like receptors, NOD1, and NOD2, in human oral epithelial cells, and their function2007

    • Author(s)
      Sugawara. Y.. A. Uehara, Y. Fujimoto, K. Fukase, T. Sasano, and H. Takada.
    • Journal Title

      Interface Oral Health Science (M. Watanabe & O. Okuno (ed.)) (Springer, Tokyo)

      Pages: 225-230

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD12007

    • Author(s)
      Uehara. A.. Y. Fujimoto, A. Kawasaki, K. Fukase, and H. Takada.
    • Journal Title

      Interface Oral Health Science (M. Watanabe & O. Okuno (ed.)) (Springer, Tokyo)

      Pages: 275-276

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Oral bacterial lipopolysaccharide acts in mice to promote sensitisation tp ovalbumin and to augment anaphylaxis via platelets.2007

    • Author(s)
      Yoshida, A., X. Deng, T. Sasano, H. Takada, S. Sugawara, and Y. Endo.
    • Journal Title

      Archives of Oral Biology 52

      Pages: 990-994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] 口腔粘膜の自然免疫2007

    • Author(s)
      上原亜希子, 菅原由美子, 高田春比古
    • Journal Title

      実験医学(増刊)粘膜免疫からの感染と免疫応答機構体の入口から呼吸器・消化器、生殖器、皮膚までの防御システム 25

      Pages: 3126-3132

    • NAID

      10024178634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Various human epithelial cells express fumctional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines.2007

    • Author(s)
      Uehara, A., Y. Fujimoto, K. Fukase, and H. Takada.
    • Journal Title

      Molecular Immunology 44

      Pages: 3100-3111

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Priming effects of microbial or inflammatory agents2007

    • Author(s)
      Sato, N., M. Kinbara, T. Kuroishi, H. Takada, K. Kimura, S. Sugawara, and Y. Endo.
    • Journal Title

      Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Priming effects of microbial or inflammatory agents in metal allergy, Springer, Tokyo

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.) 分担: Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar bacterial cell-wall peptidoglycans, activate human epithelial cells2007

    • Author(s)
      Uehara, A., Y. Fujimoto, A. Kawasaki, K Fukase, and H. Takada.
    • Journal Title

      Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.) 分担: Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD1, Springer, Tokyo

    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] Functional TLRs and NODs in human gingival fibroblasts.2007

    • Author(s)
      Uehara, A., and H. Takada.
    • Journal Title

      Journal of Denal. Reearch 86

      Pages: 249-254

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells2007

    • Author(s)
      Uehara, A., Y. Fujimoto, A. Kawasaki, K. Fukase, and H. Takada.
    • Journal Title

      Interface Oral Health Science 2007: M. Watanabe & O. Okuno(ed.)分担: Meso-diaminopimelic acid and meso-lanthionine, amino acids peculiar to bacterial cell-wall peptidoglycans, activate human epithelial cells in culture via NOD1, Springer, Tokyo

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbia1 peptides, but not proinflammatory cytokines.2007

    • Author(s)
      Uehara, A., Y. Fujimoto, K. Fukase, and H. Takada.
    • Journal Title

      Molecular Immunology 44

      Pages: 3200-3111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Journal Article] cANCAによる単球・マクロファージ系細胞活性化2007

    • Author(s)
      上原亜希子, 高田春比古
    • Journal Title

      臨床免疫・アレルギー科 48

      Pages: 559-563

    • NAID

      40015753880

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] An antibacterial protein CAP18/LL-37 enhanced production of hepatocyte growh factor in human gingival fibroblast cultures2007

    • Author(s)
      Maeda, H., A. Uehara. T. Saito, H. Mayanagi, I. Nagaoka, and H. Takada.
    • Journal Title

      Interface Oral Health Science (M. Watanabe & O. Okuno (ed.)) (Springer, Tokyo)

      Pages: 283-284

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Oral bacterial lipopolysaccharide acts in mice to promote sensitisation to ovalbumin and to augment anaphylaxis via platelets.2007

    • Author(s)
      Yoshida, A., X. Deng, T. Sasano, H. Takada, S. Sugawara, and Y. Endo.
    • Journal Title

      Archives of Oral Biology 52

      Pages: 990-994

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling.2006

    • Author(s)
      Takada H, Uehara A
    • Journal Title

      Current Pharmaceutical Design 12(印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Involveent of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuring anaphylaxis-like shock in mice.2006

    • Author(s)
      Yamaguchi K, Yu Z, Kusumoto H, Sugawara Y, Kawamura H, Takada H, Yokochi T, Sugawara S, Endo Y
    • Journal Title

      Biochemica et Biophysica Acta 1762・3

      Pages: 269-275

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Toll-like receptors, NOD1, and NOD2 in oral epithelial cells2006

    • Author(s)
      Sugawara, Y., A. Uehara, Y. Fujimoto, S. Kusumoto, K. Fukase, K. Shibata, S. Sugawara, T. Sasano, and H. Takada.
    • Journal Title

      Journal of Denal. Reearch. 85

      Pages: 524-529

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuring anaphylaxis-like shock in mice.2006

    • Author(s)
      Yamaguchi K, Yu Z, Kumamoto H, Sugawara Y, Kawamura H, Takada H, Yokochi T, Sugawara S, Endo Y
    • Journal Title

      Biochimica et Biophysica Acta : Molecular Basis of Disease 1762-3

      Pages: 269-275

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] エンドトキシンショック2006

    • Author(s)
      高田春比古, 上原亜希子
    • Journal Title

      化学療法の領域 22・3

      Pages: 327-333

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Toll-like receptors, NOD1 and NOD2 in oral epithelial cells.2006

    • Author(s)
      Sugawara Y, Uehara A, Fujimoto Y, Kusumoto S, Fukase K, Shibata K, Sugawara S, Sasano T, Takada H
    • Journal Title

      Journal of Dental Research 85(印刷中)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.2006

    • Author(s)
      Uehara, A., Y. Fujimoto, A. Kawasaki, S. Kusumoto, K. Fukase, and H. Takada.
    • Journal Title

      Journal of Immunology 177

      Pages: 1796-1804

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling.2006

    • Author(s)
      Takada, H., and A. Uehara
    • Journal Title

      Curr. Phrmaceut. Design 12

      Pages: 4163-4172

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuing anaphylaxis-like shock in mice.2006

    • Author(s)
      Yamaguchi, K., Z. Yu, H. Kumamoto, Y. Sugawara, H. Kawamura, H. Takada, T. Yokochi, S. Sugawara, and Y. Endo.
    • Journal Title

      Biochim. Biophys. Acta: Mol. Basis Dis. 1762

      Pages: 269-275

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Mouse and human cell activation by N-dodecanoyl-DL-homo-serine lactone, a Chromobacterium violaceum autoinducer.2006

    • Author(s)
      Gomi, K., T. Kikuchi, Y. Tokue, S. Fujimura, A. Uehara, H. Takada, A. Watanabe, and T. Nukiwa.
    • Journal Title

      Infection and Immunity. 74

      Pages: 7029-7031

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuring anaphylaxis-like shock in mice.2006

    • Author(s)
      Yamaguchi K, Yu Z, Kumamoto H, Sugawara Y, Kawamura H, Takada H, Yokochi T, Sugawara S, Endo Y
    • Journal Title

      Biochimica et Biophysica Acta : Molecular Basis of Disease 1762・3

      Pages: 269-275

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Mouse and human cell activation by N-dodevanoyl-DL-homoserine lactone, a Chromobacterium violaceum autoinducer2006

    • Author(s)
      Gomi, K., T. Kiknchi, Y. Tokue, S. Fujimura, A. Uehara. H. Takada. A Watanab and T. Nuknva.
    • Journal Title

      Infect. Immun 74-12

      Pages: 7029-7031

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Toll-like receptors, NOD1, and NOD2 in oral epithelial cells.2006

    • Author(s)
      Sugawara Y, Uehara A, Fujimoto Y, Kusumoto S, Fukase K, Shibata K, Sugawara S, Sasano T, Takada H
    • Journal Title

      Journal of Dental Research 85・6

      Pages: 524-529

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling.2006

    • Author(s)
      Takada H, Uehara A
    • Journal Title

      Current Pharmaceutical Design 12・32

      Pages: 4163-4172

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Mouse and human cell activation by N-dodecanoyl-DL-homoserine lactone, a Chromobacterium violaceum autoinducer.2006

    • Author(s)
      Gomi K, Kikuchi T, Tokue Y, Fujimura S, Uehara A, Takada H, Watanabe A, Nukiwa T
    • Journal Title

      Infection and Immunity 74・12

      Pages: 7029-7031

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Involvement of Kupffer cells in lipopolysaccharide-induced rapid accumulation of platelets in the liver and the ensuing anaphylaxis-like shock in mice2006

    • Author(s)
      Yamaguchi, K. Z. Yu, H. Kumamoto, Y. Sugawara, H. Kawamura, H. Takada. T. Yokochi, S. Sugawara, and Y. Endo.
    • Journal Title

      Biochim. Biophys. Acta: Mol. Basis Dis 1762-3

      Pages: 269-275

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD12006

    • Author(s)
      Uehara, A, Y. Fujimoto, A, Kawasaki, S, Kusumoto, K, Fukase, and H, Takada.
    • Journal Title

      J. Immunol 177-3

      Pages: 1796-1804

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] NODI/2とその免疫応答における役割2006

    • Author(s)
      上原亜希子, 高田春比古
    • Journal Title

      臨床免疫 45・2

      Pages: 275-280

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling2006

    • Author(s)
      Takada, H, and A, Uehara.
    • Journal Title

      Curr. Phrmaceut. Design 12-32

      Pages: 4163-4172

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Toll-likereceptors, NOD1 and NOD2 in oral epithelial cells.2006

    • Author(s)
      Sugaweara Y, Uehara A, Fujimoto Y, Kusumoto S, Fukase K, Shibata K, Sugawara S, Sasano T, Takada H
    • Journal Title

      The Journal of Dental Research (印刷中)

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Meso-diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.2006

    • Author(s)
      Uehara A, Fujimoto Y, Kawasaki A, Kusumoto S, Fukase K, Takada H
    • Journal Title

      The Journal of Immunology 177・3

      Pages: 1796-1804

    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling.2006

    • Author(s)
      Takada H, Uehara A
    • Journal Title

      Current Pharmaceutical Design (印刷中)

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Toll-like receptors, NOD1, and NOD2 in oral epithelial cells2006

    • Author(s)
      Sugawara, Y. A. Uehara. Y. Fujimoto, S. Kusumoto, K. Fukase, K. Shibata, S. Sugawara, T. Sasano, and H. Takada.
    • Journal Title

      J. Dent. Res 85-6

      Pages: 524-529

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Journal Article] 口と免疫機構 -口腔粘膜の自然免疫応答-2006

    • Author(s)
      高田春比古, 上原亜希子
    • Journal Title

      歯界展望 107・3

      Pages: 590-594

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Critical roles of platelets in lipopolysaccharide-induced lethality : effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome.2005

    • Author(s)
      Yu Z, Ohtaki Y, Kai K, Sasano T, Shimauchi H, Yokochi T, Takada H, Sugawara S, Kumagai K, Endo Y.
    • Journal Title

      International Immunopharmacology 5-3

      Pages: 571-580

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells togenerate interleukin-12 and T helper type 1 cells.2005

    • Author(s)
      Tada H, Aiba S, Shibata K, Ohteki T, Takada H
    • Journal Title

      Infection and Immunity 73・12

      Pages: 7967-7976

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Critical roles of platelets in lipopolysaccharide-induced lethality : effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome.2005

    • Author(s)
      Yu Z, Ohtaki Y, Kai K, Sasano T, Shimauchi H, Yokochi T, Takada H, Sugawara S, Kumagai K, Endo Y
    • Journal Title

      International Immunopharmacology 5・3

      Pages: 571-580

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via Toll-like receptors NOD1 and NOD2 in human oral epithelial cell.2005

    • Author(s)
      Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Satta Y, Sasano T, Sugawara S, Takada H.
    • Journal Title

      Cullular Microbiology 7-5

      Pages: 657-686

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Critical roles of platelets in lipopolysaccharide-induced lethality : effects of glycyrrhizin and possible strategy for acute respiratory distress syndrome.2005

    • Author(s)
      Yu Z, Ohtaki Y, Kai K, Sasano T, Shimauchi H, Yokochi T, Takada H, Sugawara S, Kumagai K, Endo Y.
    • Journal Title

      International Immunopharmacology 5(3)

      Pages: 571-580

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Involvement of neutrophil recruitment and protease-activated receptor 2 activation in the induction of IL-18 in mice.2005

    • Author(s)
      Ikawa K, Nishioka T, Yu Z, Sugawara Y, Kawagoe J, Takizawa T, Primo V, Nikolic B, Kuroishi T, Sasano T, Shimauchi H, Takada H, Endo Y, Sugawara S.
    • Journal Title

      Journal of Leukocyte Biology 78-5

      Pages: 1118-1126

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Involvement of neutrophil recruitment and protease-activated receptor 2 activation in the induction of IL-18 in mice.2005

    • Author(s)
      Ikawa K, Nishioka T, Yu Z, Sugawara Y, Kawagoe J, Takizawa T, Primo V, Nikolic B, Kuroishi T, Sasano T, Shimauchi H, Takada H, Endo Y, Sugawara S
    • Journal Title

      Journal of Leukocyte Biology 78・5

      Pages: 1118-1126

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Involvement of neutrophil recruitment and protease-activated ereceptor 2 activation in the induction of IL-18 in mice.2005

    • Author(s)
      Ikawa K, Nishioka T, Yu Z, Sugawara Y, Kawagoe J, Takizawa T, Primo V, Nikolic B, Kuroishi T, Sasano T, Shimauchi H, Takada H, Endo Y, Sugawara S
    • Journal Title

      Journal of Leukocyte Biology 78・5

      Pages: 1118-1126

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture.2005

    • Author(s)
      Uehara A, Muramoto K, Imamura T, Nakayama K, Potempa J, Travis J, Sugawara S, Takada H
    • Journal Title

      The Journal of Immunology 175・9

      Pages: 6076-6084

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via Toll-like receptors, NOD1 and NOD2 in human oral epithelial cells.2005

    • Author(s)
      Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto Y, Satta Y, Sasano T, Sugawara S, Takada H
    • Journal Title

      Cellular Microbiology 7・5

      Pages: 675-686

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture.2005

    • Author(s)
      Uehara A, Muramoto K, Imamura T, Nakayama K, Potempa J, Travis J, Sugawara S, Takada H.
    • Journal Title

      The Journal of Immunology 175-9

      Pages: 6076-6084

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture.2005

    • Author(s)
      Uehara A, Yang S, Fujimoto Y, Fukase K, Kusumoto S, Shibata K, Sugawara S, Takada H.
    • Journal Title

      Cellular Microbiology 7(1)

      Pages: 53-61

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Arginine-specific gingipains from Porphyromonas gingivalis stimulate production of hepatocyte growth factor (scatter factor) through protease-activated receptors in human gingival fibroblasts in culture.2005

    • Author(s)
      Uehara A, Muramoto K, Imamura T, Nakayama K, Potenpa J, Travis J, Sugawara S, Takada H
    • Journal Title

      The Journal of Immunology 175・9

      Pages: 6076-6084

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyl dipeptide ebahances osteoclast formation induced by lipopolysaccharide, IL-1α, and TNF-α through nucleotide-binding ologomerization domain 2-mediated signaling in osteoblasts.2005

    • Author(s)
      Yang S, Tkahashi N, Yamashita T, Sato N, Tkahashi M, Mogi M, Uematsu T, Kobayashi Y, Nakamichi Y, Takeda K, Akira S, Takada H, Udagawa N, Furusawa K.
    • Journal Title

      The Journal of Immunology 175-3

      Pages: 1956-1964

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture.2005

    • Author(s)
      Uehara A, Yang S, Fujimoto Y, Fukase K, Kusumoto S, Shibata K, Sugawara S, Takada H.
    • Journal Title

      Cullular Microbiology 7-1

      Pages: 53-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyl dipeptide ebahances osteoclast formation induced by lipopolysaccharide, IL-1α, and TNF-α through nucleotide-binding ologomerization domain 2-mediated signaling in osteoblasts.2005

    • Author(s)
      Yang S, Tkahashi N, Yamashita T, Sato N, Tkahashi M, Mogi M, Uematsu T, Kobayashi Y, Nakamichi Y, Takeda K, Akira S, Takada H, Udagawa N, Furusawa K
    • Journal Title

      The Journal of Immunology 175・3

      Pages: 1956-1964

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Higher induction of histamine-forming enzyme, histidine decarboxylase, in various tissues in muramyldipeptide- and desmuramylpeptide-primed mice following intravenous injection of endotoxin.2005

    • Author(s)
      Funayama H, Huang L, Hagiwara M, Endo Y, Takada H.
    • Journal Title

      Ibid

      Pages: 209-210

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Effects of muramyl dipeptide on osteoclast formation induced by LPS, IL-1 and TNF-α in mouse culture system.2005

    • Author(s)
      Yang S, Takahashi N, Tkahashi M, Takada H, Furusawa K, Udagawa N.
    • Journal Title

      Ibid

      Pages: 211-212

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Synergistic effect of Nod1 and Nod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells.2005

    • Author(s)
      Tada H, Aiba S, Shibata K, Ohteki T, Takada H.
    • Journal Title

      Infection and Immunity 73-12

      Pages: 7967-7976

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture.2005

    • Author(s)
      Uehara A, Yang S, Fujimoto Y, Fukase K, Kusumoto S, Shibata K, Sugawara S, Takada H
    • Journal Title

      Cellular Microbiology 7・1

      Pages: 53-61

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Muramyl dipeptide enhances osteoclast formation induced by lipopolysaccharide, IL-1α, and TNF-α through nucleotide-binding oligomerization domain 2-mediated signaling I osteoblasts.2005

    • Author(s)
      Yang S, Takahashi N, Yamashita T, Sato N, Takahashi M, Mogi M, Uematsu T, Kobayashi Y, Nakamichi Y, Takeda K, Akira S, Takada H, Udagawa N, Furusawa K.
    • Journal Title

      The Journal of Immunology 175・3

      Pages: 1956-1964

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Chemically synthesized pathogen-associated molecular patterns increase the expression of peptidoglycan recognition proteins via Toll-like receptors, NOD1 and NOD2 in human oral epithelial cell.2005

    • Author(s)
      Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Satta Y, Sasano T, Sugawara S, Takada H
    • Journal Title

      Cellular Microbiology 7・5

      Pages: 675-686

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Upregulation of PGRPs by chemically synthesized pathogen-associated molecular patterns via Toll-like receptors, NOD1 and NOD2 in oral epithelial cells.2005

    • Author(s)
      Uehara A, Sugawara Y, Kurata S, Fujimoto Y, Fukase K, Kusumoto S, Sasano T, Shibata K, Sugawara S, Takada H.
    • Journal Title

      Interface Oral Health Science (International Congress Series 1284)(M.Watanabe, N.Takahashi, H.Takada(eds))(Elsevier, Amsterdam)

      Pages: 163-168

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Endogenous membrane-bound IL-15 sustains recruitment of IL-2Rβ and common γ through activationion of NF-κB in human gingival fibroblasts2005

    • Author(s)
      Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S.
    • Journal Title

      Ibid

      Pages: 175-180

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Synergistic effect of Nod1 andNod2 agonists with Toll-like receptor agonists on human dendritic cells to generate interleukin-12 and Thelper type 1 cells.2005

    • Author(s)
      Tada H, Aiba S, Shibata K, Ohteki T, Takada H
    • Journal Title

      Infection and Immunity 73・12

      Pages: 7967-7976

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to proteinase 3 activate the cells through protease-activated receptor-2.2004

    • Author(s)
      Uehara A, Sugawara Y, Sasano T, Takada H, Sugawara S.
    • Journal Title

      The Journal of Immunology 173-6

      Pages: 4179-4189

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Role of caspase in CD8O expression of superantigen-stimulated monocytes.2004

    • Author(s)
      Shinihara F, Sato K, Suzuki M, Takada H, Echigo S, Rikiishi H.
    • Journal Title

      International Journal of Molecular Medicine 14(2)

      Pages: 241-246

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1α2004

    • Author(s)
      Sato N, Takahashi N, Suda K, Nakamura M, Yamaki M, Ninomiya T, Kobayashi Y, Takada H, Shibata K, Yamamoto M, Takeda K, Akira S, Noguchi T, Udagawa N.
    • Journal Title

      Journal of Experimental Medicine 200-5

      Pages: 601-611

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to protease 3 activate the cells through protease-activated receptor-2.2004

    • Author(s)
      Uehara A, Sugawara Y, Sasano T, Takada H, Sugawara S
    • Journal Title

      The Journal of Immunology 173(6)

      Pages: 4179-4189

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Proinflammatory cytokines induce proteinase 3 as membrane-bound and secretory forms in human oral epithelial cells and antibodies to proteinase 3 activate the cells through protease-activated receptor-2.2004

    • Author(s)
      Uehara A, Sugawara Y, Sasano T, Takada H, Sugawara S
    • Journal Title

      The Journal of Immunology 173・6

      Pages: 4179-4189

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Endogenous IL-15 sustains recruitment of IL-2Rβ and common γ and IL-2-mediated chemokine production in normal and inflamed human gingival fibroblasts.2004

    • Author(s)
      Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S.
    • Journal Title

      The Journal of Immunology 173-8

      Pages: 5180-5188

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] MyD88 but not TRIF is essential for osteoclastogenes is induced by lipopolysaccharide, diacyl lipopeptide, and IL-1α.2004

    • Author(s)
      Sato N, Takahashi N, Suda K, Nakamura M, Yamaki M, Ninomiya T, Kobayashi Y, Takada H, Shibata K, Yamamoto M, Takeda K, Akira S, Noguchi T, Udagawa N.
    • Journal Title

      Journal of Experimental Medicine 200(5)

      Pages: 601-611

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] MyD88 but not TRIF is essential for osteoclastogenesis induced by lipopolysaccharide, diacyl lipopeptide, and IL-1α2004

    • Author(s)
      Sato N, Takahashi N, Suda K, Nakamura M, Yamaki M, Ninomiya T, Kobayashi Y, Takada H, Shibata K, Yamamoto M, Takeda K, Akira S, Noguchi T, Udagawa N
    • Journal Title

      Journal of Experimental Medicine 200・5

      Pages: 601-611

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Endogenous IL-15 sustains recruitment of IL-2Rβ and common γ and IL-2-mediated chemokine production in normal inflamed gingival fibroblasts.2004

    • Author(s)
      Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S.
    • Journal Title

      The Journal of Immunology 173(8)

      Pages: 5180-5188

    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Endogenous IL-15 sustains recruitment of IL-2Rβ and common γ and IL-2-mediated chemokine production in normal and inflamed human gingival fibroblasts.2004

    • Author(s)
      Ozawa A, Tada H, Sugawara Y, Uehara A, Sasano T, Shimauchi H, Takada H, Sugawara S
    • Journal Title

      The Journal of Immunology 173・8

      Pages: 5180-5188

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Role of caspase in CD80 expression of superantigen-stimulated monocytes.2004

    • Author(s)
      Shinohara F, Sato K, Suzuki N, Takada H, Exhigo S, Rikiishi H.
    • Journal Title

      International Journal of Molecular Medicine 14-2

      Pages: 241-246

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Role of caspase in CD80 expression of supernatigen-stimulated monocytes.2004

    • Author(s)
      Shinohara F, Sato K, Suzuki M, Takada H, Echigo S, Rikiishi H
    • Journal Title

      International Journal of Molecular Mecdicine 14・2

      Pages: 241-246

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Enhancement of TLR-mediated innate immune responses by peptidoglycans through NOD signaling.

    • Author(s)
      Takada H, Uehara A.
    • Journal Title

      Current Pharmaceutical Design (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Journal Article] Toll-like receptors, NOD1 and NOD2 in oral epithelial cells.

    • Author(s)
      Sugawara Y, Uehara A, Fujimoto Y, Kusumoto S, Fukase K, Shibata K, Sugawara S, Sasano T, Takada H.
    • Journal Title

      Journal of Dental Research. (In press)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16390519
  • [Presentation] LPSにより誘導される破骨細胞形成および骨吸収に対するMDPの作用について2014

    • Author(s)
      石田匡彦、北浦英樹、木村桂介、杉澤晴紀、高田春比古、山本照子
    • Organizer
      第65回東北大学歯学会
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-13
    • Data Source
      KAKENHI-PROJECT-25670794
  • [Presentation] Analgesic effects of NOD1 and NOD2 agonists2009

    • Author(s)
      Sato T, Endo Y, Shimauchi H, Takada H
    • Organizer
      The 3^<rd> International Symposium for Interface Oral Health Science
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Anaphylaxis-like shock induced by LPS plus anti-neutrophil antibodies in mice2009

    • Author(s)
      Tanaka N, Nagai Y, Kuroishi T, Takada H, Endo Y, Sugawara S
    • Organizer
      The 3^<rd> International Symposium for Interface Oral Health Science
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Muramyldipeptide augments the actions of LPS via multiple fashions in mice2009

    • Author(s)
      Shikama Y, Kuroishi T, Nagai Y, Shimauchi H, Takada H, Sugawara S, Endo Y
    • Organizer
      The 3^<rd> International Symposium for Interface Oral Health Science
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Muramyl-dipeptide(MDP)による炎症性サイトカイン産生及びエンドトキシンショック増強効果2008

    • Author(s)
      Shikama Y, Shimauchi H, Takada H, Sugawara S, Endoh Y
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] NOD1アゴニストFK565の鎮痛作用2008

    • Author(s)
      佐藤匡、遠藤康男、島内英俊、高田春比古
    • Organizer
      第14回日本エンドトキシン研究会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Muramyl-dipeptide(MDP)による炎症性サイトカイン産生及びエンドトキシンショック増強効果とそのメカニズム解析2008

    • Author(s)
      四釜洋介、島内英俊、菅原俊二、高田春比古、遠藤康男
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] ペプチドグリカンの免疫生物活性研究の歴史(シンポジウム座長・シンポジスト)2008

    • Author(s)
      高田春比古
    • Organizer
      第81回日本細菌学会総会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] マウスにおけるニッケルアレルギー : elicitation stepにおける自然免疫の関与2008

    • Author(s)
      船山ひろみ、黄玲、金原正敬、柴田健一郎、朝田芳信、菅原俊二、高田春比古、遠藤康男
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] LPSと好中球によりマウスに誘導されるアナフィラキシー様ショック2008

    • Author(s)
      Tanaka Y, Nagai Y, Kuroishi T, Takada H, Endo Y, Sugawara S.
    • Organizer
      第38回日本免疫学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] ヒト歯根膜細胞(PDL)の自然免疫系 : Toll-like receptor(TLR)系分子、NOD1およびNOD2分子の発現とその機能2008

    • Author(s)
      青沼智、上原亜希子、山本照子、高田春比古
    • Organizer
      第14回日本エンドトキシン研究会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] ヒト歯根膜細胞(PDL)のToll-like receptor (TLR)系分子およびNOD1/2分子の発現とその機能2008

    • Author(s)
      青沼智、上原亜希子、山本照子、高田春比古
    • Organizer
      第50回歯科基礎医学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] ペプチドグリカンの免疫生物活性研究の歴史(シンポジウム座長・シンポジスト)2008

    • Author(s)
      高田春比古
    • Organizer
      第81回日本細菌学会総会
    • Place of Presentation
      京都市
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Enhancement of TLR-mediated innate immune responses by NOD1/2signaling2007

    • Author(s)
      Takada, H., M. Hagiwara, H. Funayama, and A. Uehara.
    • Organizer
      The 7^<th> Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji, Hyogo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] 歯学領域の自然免疫研究(シンポジウム司会・シンポジスト)2007

    • Author(s)
      高田春比古
    • Organizer
      第49回歯科基礎医学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] A polymer-type water-soluble peptidoglycan exhibited both Toll-like receptor 2-and NOD2-agonistic activities, resulting in synergistic activation of human monocytic cells2007

    • Author(s)
      Natsuka M., A. Uehera, and H. Takada
    • Organizer
      1^<st> Congress of the Society of Innate Immunity
    • Place of Presentation
      Ankara, Turkey
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce antimicrobial peptides, but not proinflmmatory cytokines2007

    • Author(s)
      Uehara, A., Y. Fujimoto, K. Fukase, and H. Takada
    • Organizer
      13^<th> International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Enhancement of TLR-mediated innate immune responses by NODI/2 signaling2007

    • Author(s)
      Takada. H., M. Hagiwara, H. Funayama, and A. Uehara
    • Organizer
      The 7^<th> Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji, Hyogo.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Bacterial peptidoglycan and innate immunity(invited speaker)2007

    • Author(s)
      Takada H
    • Organizer
      4th Lyon-Tohoku Engineering & Science Forum towards the Joint Laboratory
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Various human epithelial cells express functional Toll-like receptors, NODI and NOD2 to produce antimicrobial peptides, but not proinflmmatory cytokines2007

    • Author(s)
      Uehara. A., Y. Fujimoto, K. Fukase, and H. Takada
    • Organizer
      13^<th> International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Enhancement of TLR-mediated innate immune responses by NOD1/2 signaling(invited speaker)2007

    • Author(s)
      Takada, H., M. Hagiwara, H. Funayama, and A. Uehara.
    • Organizer
      7th Awaji International Forum Infection and Immunity
    • Place of Presentation
      Awaji, Hyogo
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Antibodies against proteinase 3(PR3)prime human monocytic cells a protease-activated receptor (PAR)-2-and NF-kappaB-dependent manner for CD14-, various Toll-like receptors, NOD1-, and 2-mediated activation.2007

    • Author(s)
      Uehara, A., and H. Takada
    • Organizer
      l^<st> Congress of the Society of Innate Immunity
    • Place of Presentation
      Ankara, Turkey
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Apolymer-type water-soluble peptidoglycan exhibited both Toll-like receptor 2- and NOD2- agonistic activities, resulting in syner gistic activation of human monocytic cells.2007

    • Author(s)
      Natsuka M., A. Uehera. and H. Takada
    • Organizer
      1^<st> Congress of the Society of Innate and Immunity
    • Place of Presentation
      Ankara, Turkey
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] NOD1ないしNOD2リガンドでプライムされたマウスでは様々なTLRリガンド刺激に対するサイトカイン応答が亢進する2007

    • Author(s)
      萩原資久、上原亜希子、横山成邦、宮田 剛、高田春比古
    • Organizer
      第4回東北バイオサイエンスシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2007-06-04
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Enhancement of TLR-mediated innate immune responses by NOD1/2 signaling(invited speaker)2007

    • Author(s)
      Takada, H., M. Hagiwara, H. Funayama, and A. Uehara.
    • Organizer
      7th Awaji International Forum Infection and Immunity
    • Place of Presentation
      Awaji, Hyogo
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Functional toll-like receptors and NODs in human oral epithelial cells.2007

    • Author(s)
      Sugawara, Y. A. Uehara. Y, Fujimoto, S. Kusumoto, K. Fukase, T. Sasano, H. Takada
    • Organizer
      1^<st> Congress of the Society of Innate and Immunity
    • Place of Presentation
      Ankara, Turkey.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce antimicrobila peptdes, but not proinflmmatory cytokines2007

    • Author(s)
      Uehara, A., Y. Fujimoto, K. Fukase, and H. Takada
    • Organizer
      13th International Congress of Mucosal Immunology
    • Place of Presentation
      Tokyo
    • Data Source
      KAKENHI-PROJECT-19658029
  • [Presentation] Crosstalk between protease-activated receptor and TLRs/NODs in innate Immunity2007

    • Author(s)
      Uehara. A., T. Sato, A. Iwashiro, S. Yokota, and H. Takada
    • Organizer
      The 20^<th> Naito Conference on In Immunity in Medicine and Biology [III]
    • Place of Presentation
      Shonan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Functional toll-like receptors and NODs in human oral epithelial cells2007

    • Author(s)
      Sugawara, Y., A. Uehara, Y, Fujimoto, S. Kusumoto, K. Fukase, T. Sasano, and H. Takada.
    • Organizer
      1st Congress of the Society of Innate Immunity
    • Place of Presentation
      Ankara, Turkey
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Antibodies against proteinase 3 (PR3) prime human monocytic cells in a protease-activated receptor (PAR)-2- and NF-kappaB-dependent manner for CD14-, various Toll-like receptors, NOD1-, and 2-mediated activation2007

    • Author(s)
      Uehara. A., and H. Takada
    • Organizer
      1^<st> Congress of the Society of Innate and Immunity
    • Place of Presentation
      Ankara, Turkey
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Bacterial peptidoglycan and innate immunity2007

    • Author(s)
      Takada H
    • Organizer
      The 4^<th> Lyon-Tohoku Engineering & Science Forum towards the Joint Laboratory
    • Place of Presentation
      Sendai
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Crosstalk between protease-activated receptor and TLRs/NODs in innateimmunity2007

    • Author(s)
      Uehara, A., T. Sato, A. Iwashiro, S. Yokota, and H. Takada
    • Organizer
      The 20^<th> Naito Conference on Innate Immunity in Medicine and Biology [III]
    • Place of Presentation
      Shonan
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Crosstalk between protease-activated receptor and TLRs/NODs in innate immunity2007

    • Author(s)
      Uehara, A., T. Sato, A, Iwashiro, S. Yokota, and H. Takada
    • Organizer
      20th Naito Conference: Innate Immunity in Medicine and Biology[III]
    • Place of Presentation
      Shonan
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Bacterial peptidoglycan and innate immunity(invited speaker)2007

    • Author(s)
      Takada H
    • Organizer
      4th Lyon-Tohoku Engineering & Science Forum towards the Joint Laboratory
    • Place of Presentation
      Sendai
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Constitutive expression of Toll-like receptors, NOD1, and NOD2 in Human oral epithelial cells and their function2006

    • Author(s)
      Sugawara, Y., A. Uehara, Y. Fujimoto, S. Kusumoto, K. Fukase, K. Shibata, T. Sasano, and H. Takada.
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antinio, Texas
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Meso-Diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD12006

    • Author(s)
      Takada, H., Y. Fujimoto, A. Kawasaki, S. Kusumoto, K. Fukase, and A. Uehara.
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antinio, Texas
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Constitutive expression of Toll-like receptors, NODI, and NOD2 in human oral epithelial cells and their function2006

    • Author(s)
      Sugawara. Y. A. Uehara. Y. Fujimoto, S. Kusumoto, K. Fukase, K. Shibata T. Sasano, and H. Takada.
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antinio, Texas.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Antibodies to proteinase 3 prime human monocytic cells via protease-activatedpreceptor-2, phospholipase C, and NF-_kB for CD14-, Toll-like receptor 2-, 3-, 4-, 7-, 8-, N0D1-, and 2-dependent activation2006

    • Author(s)
      Uehara. A., and H. Takada
    • Organizer
      The 6^<th> Awaji International Forum Infection and Immunity (Hyogo)
    • Place of Presentation
      Awaji, Hyogo
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Meso-Diaminopimelic acid and meso-lanthionine, amino acids specific to bacterial peptidoglycans, activate human epithelial cells through NOD1.2006

    • Author(s)
      Takada. H., Y. Fujimoto, A. Kawasaki, S. Kusumoto, K. Fukase, and A. Uehara
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antinio, Texas.
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Antibodies to proteinase 3 prime human monocytic cells via protease-activated preceptor-2, phospholipase C, and NF-kB for CD14-, Toll-like receptor 2-,3-,4-,7-,8-, NOD1-, and 2-dependent activation2006

    • Author(s)
      Uehara, A., and H. Takada
    • Organizer
      The 6th Awaji International Forum Infection and Immunity
    • Place of Presentation
      Awaji, Hyogo
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Antibodies to proteinase 3 (PR3) prime human monocytic cells in a protease-activated receptor (PAR)-2-, proteinase 3-, phospholipase C-, and NF-kB-dependent manner for CD14-, Toll-like receptor (TLR) 2-,3-,4-,7-,8-, NOD1-, and 2-mediated activation2006

    • Author(s)
      Uehara, A., and H. Takada
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antinio, Texas
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] Antibodies to proteinase 3 (PR3) prime human monocytic cells in a protease-activated receptor (PAR)-2-, proteinase 3-, phospholipase C-, and NF-k_B-dependent manner for CD14-, Toll-like receptor (TLR)2-, 3-, 4-, 7-, 8-, NOD1-, and 2-mediated activation2006

    • Author(s)
      Uehara. A., and H. Takada.
    • Organizer
      Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
    • Place of Presentation
      San Antion, Texaa
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390484
  • [Presentation] エンドトキシンをはじめとする菌体成分と自然免疫 -研究の歴史-

    • Author(s)
      高田春比古
    • Organizer
      エンドトキシン試験法セミナー2015
    • Place of Presentation
      豊中(10日)、東京(13日)
    • Year and Date
      2015-02-10 – 2015-02-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670794
  • [Presentation] Porphyromonas gingivalisジンジパインはIL-33誘導を介してヒト歯肉上皮細胞のCAP18/LL-37産生をダウンレギュレーションする

    • Author(s)
      多田浩之、松下健二、長岡 功、高田春比古
    • Organizer
      第20回日本エンドトキシン・自然免疫研究会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-05 – 2014-12-06
    • Data Source
      KAKENHI-PROJECT-25670794
  • [Presentation] Porphyromonas gingivalisによるヒト歯肉上皮細胞のLL-37発現誘導はIL-33により下方制御される

    • Author(s)
      多田浩之、松下健二、高田春比古
    • Organizer
      第56回歯科基礎医学会
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25670794
  • 1.  SUGAWARA Shunji (10241639)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  NEMOTO Eiji (40292221)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 3.  OGAWA Tomohiko (80160761)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 4.  HAMADA Shigeyuki (60028777)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  UEHARA Akiko (00431510)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 83 results
  • 6.  FUNAYAMA Hitomi (00359530)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 7.  ENDO Yasuo (50005039)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 8.  新垣 理恵子 (40231120)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  KOGA Toshihiko (10037541)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  MATSUSHITA Kenji (90253898)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  TADA Hiroyuki (70431632)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 12.  MORISAKI Ichijiro (30116115)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  RIKIISHI Hidemi (70091767)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  TSUJIMOTO Masachiko (50144499)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  三原 丞二 (20219710)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  永尾 重喜 (50112131)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  中村 雅典 (50180394)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  SUGIYAMA Akiko
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 19.  OOSHIMA Takashi (80116003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  IZUMITANI Akira (70168277)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KAWAGOE Masataka (40028741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ARIMURA Yuko (30222764)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  IWAMOTO Yuko (10191454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NAGAOKA Shigetaka (10155913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  HANAUMI Kiyoshi (50005063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  SAKODA Yoshinori (10235236)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  SUGAWARA Yumiko (30235866)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 20 results
  • 28.  AMAKO Kazunobu (20078752)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  NAKAE Taiji (50102851)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KAWATA Tomio (60035368)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  KANEMASA Yasuhiro (80330059)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  KATO Keijiro (50028718)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  OKAHASHI Nobuo (40150180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  KIMURA Shigenobu (10177917)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  石田 良介 (10223009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  上杉 由祈恵 (40201347)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  松下 信美 (70264447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  川畑 義裕 (70274842)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  北澤 春樹 (10204885)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 40.  向井 徹 (50209970)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 41.  戸田 洋一郎
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 42.  TODA Yoichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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