OOTA Ken 大田健

… Alternative Names

大田健オオタケン

OHTA Ken 大田健

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Researcher Number	30160500
Other IDs
External Links
Affiliation (Current)	2025: 帝京大学, 医学部, 教授 2025: 独立行政法人国立病院機構東京病院(臨床研究部), 臨床研究部, 名誉院長
Affiliation (based on the past Project Information) *help	2017 – 2019: 独立行政法人国立病院機構東京病院(臨床研究部), 臨床研究部, 名誉院長 2017: 国立病院機構, 東京病院, 院長 2014: 帝京大学, 内科, 教授 2008 – 2010: 帝京大学, 医学部, 教授 2005: 医学部, 教授 … More 1999 – 2005: 帝京大学, 医学部, 教授 1997: Department of Medicine Teikyo University School of Medicine Professor, 医学部, 教授 1992 – 1996: 帝京大学, 医学部, 助教授 1986: same as above, Assistant, 医学部・物療内科, 助手 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine / 内科学一般 / Otorhinolaryngology / 膠原病・アレルギー・感染症内科学 / Respiratory organ internal medicine
Keywords	Principal Investigator GM-CSF / マウス / 気道過敏症 / 気道過敏性 / 気管支喘息 / サイトカイン / 抗体療法 / 生体分子 / CpG / linsitinib … More / 特発性肺線維症 / マクロファージ / 肺線維芽細胞 / IGF-1 / Anti-GM-CSF antibody / Airway hyperresponsivenss / Allergen sensitization / mouse / Immunogloblin / Bronchial epithelial cells / Asthma / 抗GM-CSF体 / 抗GM-CSF抗体 / 抗原感作 / 免疫グロブリン / 気道上皮細胞 / xpression of mRNA / M-CSF / ast cells / irway hyperresponsiveness / cetylcholine (Ach) / ir pollutants / urine model / ronchial asthma / リンパ球 / mRNAの発現 / マスト細胞 / アセチルコリン(Ach) / 大気汚染物質 / 気管支肺胞洗浄(BAL) / hydroxy proline(HOP)量 / 抗IL-6抗体 / 抗PDGF抗体 / 線維芽細胞 / hydroxyproline(HOP) / IL-6 / IL-8 / PDGF / シリカビーズ / 中和抗体 / 肺線維症 … More Except Principal Investigator PDGF / サイトカイン / cytokine / mouse / マウス / 好酸球 / 気管支喘息 / IL-4 / interstitial pneumonia / transgenic / hepatitis C virus / pulmonary fibrosis / 間質性肺炎 / シリカ / トランスジェニック / 肺線維症 / リモデリング / TGF-β / IgE / 鼻ポリープ / 慢性副鼻腔炎 / 副鼻腔炎 / ウイルス / マスト細胞 / hyperreactive airway / Bronchial athma / 気道の反応性 / モルモット / signal transduction / chemokine / eosinophil / bronchial epithelial cell / remodeling / bronchial asthma / シグナル伝達 / ケモカイン / 気道上皮細胞 / apoptosis / 肝炎 / HCV / 肺繊維症 / アポトーシス / トランジェスニック / C型肝炎 / silica / 肉芽腫 / シェーグレン症候群 / envelope protein / core protein / 特発性間質性肺炎 / トランスジェニックマウス / C型肝炎ウイルス / PDGE / C型肺炎ウイルス / Airway hyperresponsivenss / Allergen sensitization / airway remodeling / Asthma / DEP / 気道過敏性 / アレルゲン / 喘息 / 国際情報交換 / クラススイッチ / ＩｇＥ / 気道感染 / 二重鎖RNA Less

Therapeutic effect of alveolar macrophage-specific anti-IGF-1 antibody for idiopathic pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Ohta Ken
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tokyo National Hospital (Clinical research)
Local increase in IgE in nasal polyps in chronic rhinosinusitis
- Principal Investigator
  
  Baba Shintaro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Local increase of IgE in nasal polyps in eosinophilic chronic rhinosinusitis
- Principal Investigator
  
  BABA Shintaro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
The host defensive role of mast cells against airway viral infection.
- Principal Investigator
  
  NAGASE Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University
Regulation of airway inflammation and remodeling by chemokines in bronchial asthma
- Principal Investigator
  
  ADACHI Tetsuya
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Teikyo University
A study of idopathic interstitial pneumonia with transgenic mouse (HCV)
- Principal Investigator
  
  NAKANO Junichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University
Molecular biologic approach for chronic and irractable asthma-analysis for mechanism of remodeling using murine asthmatic model
- Principal Investigator
  
  YAMASHITA Naomi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Teikyo University School of Medicine
A study of interstitial pneumonia with HCV transgenic mouse
- Principal Investigator
  
  NAKANO Junici
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University
Molecular biologic approach for clarification of the role of bronchial epithelial cells for development of asthmaPrincipal Investigator
- Principal Investigator
  
  OHTA Ken
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University School of Medicine
Mechanisms to induce bronchial asthma - an approach by means of molecular biology clarify how airway hyperresponsiveness is expressed with air pollutants in micePrincipal Investigator
- Principal Investigator
  
  OHTA Ken
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University
肺線維症に関与するサイトカインの同定一免疫学的および分子生物学的アプローチPrincipal Investigator
- Principal Investigator
  
  大田健
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Teikyo University
Production of hyperreactive guinea pig colony and studies of immunological mechanism of bronchial asthma.
- Principal Investigator
  
  MIYAMOTO Terumasa
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  University of Tokyo, School of Medicine

[Book] アレルギーの臨床 (0285-6379)39巻1号　内服及び吸入用のセフェム系抗菌薬がアナフィラキシーの原因と考えられた一例(原著論文/症例報告)2019
- Author(s)
  酒瀬川裕一, 小林このみ, 小泉佑太, 田中祐輔, 三好昭暉, 杉本直也, 倉持美知雄, 新井秀宜, 長瀬洋之, 山口正雄, 大田健
- Total Pages
  4
- Publisher
  (株)北隆館
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] アレルギーの臨床 (0285-6379)38巻9号　「特集/アレルギー疾患における最新の治療」に寄せる　重症喘息の治療コンセプト(解説)2018
- Author(s)
  大田健, 佐々木絢子, 江本夏伯
- Total Pages
  6
- Publisher
  (株)北隆館
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] 総合診療 (2188-8051)28巻8号　【80歳からの診療スタンダードUp to Date-Silver Standard】80歳以上の高齢者の外来診療　ここがポイント! COPD/喘息診療スタンダードUp to Date(解説/特集)2018
- Author(s)
  大田　健
- Total Pages
  5
- Publisher
  (株)医学書院
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] 保険診療 (0385-8588)73巻7号　こうして医療機関を変えてきた!療養所を母体とする公的病院の一般病院への転換と経営改善への道のり(4)(解説)2018
- Author(s)
  大田　健
- Total Pages
  2
- Publisher
  (株)医学通信社
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] アレルギーの臨床 (0285-6379)38巻6号　【アレルギーマーチ予防の考え方】反復する腹痛を主訴とする遺伝性血管性浮腫の1例(原著論文/症例報告/特集)2018
- Author(s)
  三好昭暉[路], 小林このみ, 新井秀宜, 長瀬洋之, 山口正雄, 大田健
- Total Pages
  3
- Publisher
  (株)北隆館
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] 保険診療 (0385-8588)73巻6号　こうして医療機関を変えてきた!　療養所を母体とする公的病院の一般病院への転換と経営改善への道のり(3)(解説)2018
- Author(s)
  大田　健
- Total Pages
  2
- Publisher
  (株)医学通信社
- Data Source
  KAKENHI-PROJECT-17K09634
[Book] Annual Review 呼吸器2008 IGF-1と呼吸器疾患40-43、20082008
- Author(s)
  是瀬洋之, 大田健
- Total Pages
  277
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590934
[Book] Annual Review呼吸器2008 IGF-1と呼吸器疾患2008
- Author(s)
  長瀬洋之,大田健
- Total Pages
  277
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Exacerbation of chronic pulmonary aspergillosis was associated with a high rebleeding rate after bronchial artery embolization2019
- Author(s)
  Ando Takahiro、Kawashima Masahiro、Masuda Kimihiko、Takeda Keita、Okuda Kenichi、Suzuki Junko、Ohshima Nobuharu、Horibe Mitsuko、Tamura Atsuhisa、Nagai Hideaki、Matsui Hirotoshi、Ohta Ken
- Journal Title
  
  Respiratory Investigation
  
  Volume: 印刷中 Issue: 3 Pages: 260-267
- DOI
  10.1016/j.resinv.2018.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08461, KAKENHI-PROJECT-17K09633, KAKENHI-PROJECT-17K09634
[Journal Article] Asthma exacerbations in patients with asthma and rhinitis: Factors associated with asthma exacerbation and its effect on QOL in patients with asthma and rhinitis2019
- Author(s)
  Ohta Ken、Tanaka Hiroshi、Tohda Yuji、Kohrogi Hirotsugu、Chihara Junichi、Sakakibara Hiroki、Adachi Mitsuru、Tamura Gen
- Journal Title
  
  Allergol. Int.
  
  Volume: 68 Issue: 4 Pages: 470-477
- DOI
  10.1016/j.alit.2019.04.008
- NAID
  130007733165
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] Secretory immunoglobulin A induces human lung fibroblasts to produce inflammatory cytokines and undergo activation2019
- Author(s)
  Arakawa S.、Suzukawa M.、Watanabe K.、Kobayashi K.、Matsui H.、Nagai H.、Nagase T.、Ohta K.
- Journal Title
  
  Clinical & Experimental Immunology
  
  Volume: 195 Issue: 3 Pages: 287-301
- DOI
  10.1111/cei.13253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09629, KAKENHI-PROJECT-17K09634
[Journal Article] ARIA pharmacy 2018 “Allergic rhinitis care pathways for community pharmacy”2019
- Author(s)
  Bosnic‐Anticevich Sinthia、Costa Elisio、Menditto Enrica、Ohta Ken,et al.
- Journal Title
  
  Allergy
  
  Volume: 印刷中 Issue: 7 Pages: 1219-1236
- DOI
  10.1111/all.13701
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] IL-9 Blockade Suppresses Silica-induced Lung Inflammation and Fibrosis in Mice2019
- Author(s)
  Sugimoto Naoya、Suzukawa Maho、Nagase Hiroyuki、Koizumi Yuta、Ro Shoki、Kobayashi Konomi、Yoshihara Hisanao、Kojima Yasuhiro、Kamiyama-Hara Asae、Hebisawa Akira、Ohta Ken
- Journal Title
  
  American Journal of Respiratory Cell and Molecular Biology
  
  Volume: 60 Issue: 2 Pages: 232-243
- DOI
  10.1165/rcmb.2017-0287oc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09629, KAKENHI-PROJECT-17K09634
[Journal Article] Methotrexate-associated Lymphoproliferative Disorder: A Rare Differential Diagnosis of Wheezes2019
- Author(s)
  Ujino Mariko、Miyoshi Shoki、Sugimoto Naoya、Arai Hidenori、Ota Yasunori、Sasajima Yuko、Kawamura Masafumi、Nagase Hiroyuki、Yamaguchi Masao、Ohta Ken
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 12 Pages: 1759-1764
- DOI
  10.2169/internalmedicine.2080-18
- NAID
  130007663656
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-06-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] Anti-interleukin 5 antibody is effective for not only severe asthma and eosinophilic pneumonia but also eosinophilic bronchiolitis2018
- Author(s)
  Tomyo Fuminori、Sugimoto Naoya、Kawamoto Masashi、Nagase Hiroyuki、Yamaguchi Masao、Ohta Ken
- Journal Title
  
  Respirology Case Reports
  
  Volume: 7 Issue: 2
- DOI
  10.1002/rcr2.397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] Efficacy and safety of benralizumab in Japanese patients with severe, uncontrolled eosinophilic asthma2018
- Author(s)
  Ohta Ken、Adachi Mitsuru、Tohda Yuji、Kamei Tadashi、Kato Motokazu、Mark Fitzgerald J.、Takanuma Masayuki、Kakuno Tadahiro、Imai Nobuyuki、Wu Yanping、Aurivillius Magnus、Goldman Mitchell
- Journal Title
  
  Allergol. Int.
  
  Volume: 67 Issue: 2 Pages: 266-272
- DOI
  10.1016/j.alit.2017.10.004
- NAID
  130006721707
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] A successful pembrolizumab treatment case of lung adenocarcinoma after becoming resistant to ALK-TKI treatment due to G1202R mutation2018
- Author(s)
  Shimada Masahiro、Tamura Atsuhisa、Yokosuka Kyoko、Kusaka Kei、Matsui Hirotoshi、Nagai Hideaki、Ohta Ken
- Journal Title
  
  Respiratory Investigation
  
  Volume: 56 Issue: 4 Pages: 365-368
- DOI
  10.1016/j.resinv.2018.04.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08461, KAKENHI-PROJECT-17K09634
[Journal Article] Expression of Siglec-8 is regulated by interleukin-5, and serum levels of soluble Siglec-8 may predict responsiveness of severe eosinophilic asthma to mepolizumab2018
- Author(s)
  Arakawa Sayaka、Suzukawa Maho、Ohshima Nobuharu、Tashimo Hiroyuki、Asari Isao、Matsui Hirotoshi、Kobayashi Nobuyuki、Shoji Shunsuke、Nagase Takahide、Ohta Ken
- Journal Title
  
  Allergol. Int.
  
  Volume: 67 Issue: Supplement.1 Pages: S41-S44
- DOI
  10.1016/j.alit.2018.03.006
- NAID
  130007485210
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09633, KAKENHI-PROJECT-17K09629, KAKENHI-PROJECT-17K09634
[Journal Article] Real-world safety and efficacy of omalizumab in patients with severe allergic asthma: A long-term post-marketing study in Japan2018
- Author(s)
  Adachi Mitsuru、Kozawa Masanari、Yoshisue Hajime、Lee Milligan Ki、Nagasaki Makoto、Sasajima Takayoshi、Miyamoto Terumasa、Ohta Ken
- Journal Title
  
  Respiratory Medicine
  
  Volume: 141 Pages: 56-63
- DOI
  10.1016/j.rmed.2018.06.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] Clinical Features and Prognosis of Nontuberculous Mycobacterial Pleuritis2018
- Author(s)
  Ando Takahiro、Kawashima Masahiro、Matsui Hirotoshi、Takeda Keita、Sato Ryota、Ohshima Nobuharu、Nagai Hideaki、Kitani Masashi、Hebisawa Akira、Ohta Ken
- Journal Title
  
  Respiration
  
  Volume: 96 Issue: 6 Pages: 507-513
- DOI
  10.1159/000490548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09633, KAKENHI-PROJECT-18K08461, KAKENHI-PROJECT-17K09634
[Journal Article] Pulmonary Adenocarcinoma, Harboring Both an <i>EGFR</i> Mutation and <i>ALK</i> Rearrangement, Presenting a Stable Disease to Erlotinib and a Partial Response to Alectinib2018
- Author(s)
  Yokoyama Akira、Tamura Atsuhisa、Miyakawa Kazuko、Kusaka Kei、Shimada Masahiro、Hirose Takashi、Matsui Hirotoshi、Kitani Masashi、Hebisawa Akira、Ohta Ken
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 16 Pages: 2377-2382
- DOI
  10.2169/internalmedicine.0383-17
- NAID
  130007434724
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-08-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09634
[Journal Article] Distribution, subtype population, and IgE positivity of mast cells in chronic rhinosinusitis with nasal polyps.2017
- Author(s)
  Baba S, Kondo K, Suzukawa M, Ohta K, Yamasoba T.
- Journal Title
  
  Ann Allergy Asthma Immunol
  
  Volume: 119 Issue: 2 Pages: 120-128
- DOI
  10.1016/j.anai.2017.05.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11353, KAKENHI-PROJECT-15K20187
[Journal Article] T-cell phenotypes in chronic rhinosinusitis with nasal polyps in Japanese patients.2015
- Author(s)
  Baba S, Kagoya R, Kondo K, Suzukawa M, Ohta K, Yamasoba T
- Journal Title
  
  Allergy Asthma Clinical Immunology
  
  Volume: 33 Issue: 1 Pages: 11-11
- DOI
  10.1186/1710-1492-5-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K20187
[Journal Article] Local increase of IgE and class switch recombination to IgE in nasal polyps in chronic rhinosinusitis2014
- Author(s)
  Shintaro Baba, Kenji Kondo, Makiko Toma‐Hirano, Kaori Kanaya, Keigo Suzukawa, Munetaka Ushio, Maho Suzukawa, Ken Ohta, Tatsuya Yamasoba
- Journal Title
  
  Clinical & Experimental Allergy
  
  Volume: 44
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791747
[Journal Article] Expression of IL-33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps.2014
- Author(s)
  Shintaro Baba, Kenji Kondo, Kaori Kanaya, Keigo Suzukawa, Munetaka Ushio, Shinji Urata, Takahiro Asakage, Akinobu Kakigi, Maho Suzukawa, Ken Ohta, Tatsuya Yamasoba
- Journal Title
  
  Laryngoscope.
  
  Volume: 124
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24791747
[Journal Article] 好酸球性副鼻腔炎のポリープ中IgE 陽性細胞の増加に関する検討2012
- Author(s)
  馬場信太郎，近藤　健二，鈴川　佳吾，鈴川　真穂，大田　　健，山岨　達也
- Journal Title
  
  耳鼻免疫アレルギー（JJIAO）
  
  Volume: 30 Pages: 162-163
- Data Source
  KAKENHI-PROJECT-24791747
[Journal Article] Leptin enhances survival and induces migration, degranulation, and cytokine synthesis of human basophils.2011
- Author(s)
  Suzukawa M, Nagase H, Ugahara I, Han K, Tashimo H, Shibui A, Koketsu R, Nakae S, Yamaguchi M, Ohta K
- Journal Title
  
  J Immunol.
  
  Volume: 186(9) Pages: 5254-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Leptin enhances survival and induces migration, degranulation, and cytokine synthesis of human basophils2011
- Author(s)
  Suzukawa M, Nagase H, Ogahara I, Han K, Tashimo H, Shibui A, Koketsu R, Nakae S, Yamaguchi M, Ohta K
- Journal Title
  
  J Immunol 186(9)
  
  Pages: 5254-5260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Reference ranges for exhaled nitric oxide fraction in healthy Japanese adult population2010
- Author(s)
  Matsunaga K, Hirano T, Kawayama T, Tsuburai T, Nagase H, Aizawa H, Akiyama K, Ohta K, Ichinose M.
- Journal Title
  
  Allergol Int 59(4)
  
  Pages: 363-367
- NAID
  10029671105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Reference ranges for exhaled nitric oxide fraction in healthy Japanese adult population.2010
- Author(s)
  Matsunaga K, Hirano T, Kawayama T, Tsuburai T, Nagase H, Aizawa H, Akiyama K, Ohta K, Ichinose M.
- Journal Title
  
  Allergol Int
  
  Volume: 59(4) Pages: 363-7
- NAID
  10029671105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Effect of tiotropium bromide on airway inflammation and remodelling in a mouse model of asthma.2010
- Author(s)
  Ohta S, Oda N, Yokoe T, Tanaka A, Yamamoto Y, Watanabe Y, Minoguchi K, Ohnishi T, Hirose T, Nagase H, Ohta K, Adachi M.
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 40(8) Pages: 1266-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Effect of tiotropium brmide on airway inflammation and remodelling in a mouse model of asthma2010
- Author(s)
  Ohta S, Oda N, Yokoe T, Tanaka A, Yamamoto Y, Watanabe Y, Minoguchi K, Ohnishi T, Hirose T, Nagase H, Ohta K, Adachi M
- Journal Title
  
  Clin Exp Allergy 40(8)
  
  Pages: 1266-1275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] アレルギー性気管支肺アスペルギルス症に続発した肺膿瘍が穿破し膿胸気管支馮瘻を呈した1例2009
- Author(s)
  原麻恵, 長瀬洋之, 林秀敏, 倉持美知雄, 石田博文, 足立哲也, 鈴木直仁, 大田健
- Journal Title
  
  日本呼吸器学会雑誌 47
  
  Pages: 432-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] アレルギー性気管支肺アスペルギルス症に続発した肺膿瘍が穿破し膿胸気管支瘻を呈した1例2009
- Author(s)
  原麻恵,長瀬洋之,林秀敏,倉持美知雄,石田博文,足立哲也,鈴木直仁,大田健
- Journal Title
  
  日本呼吸器学会雑誌 47
  
  Pages: 432-437
- NAID
  10024824139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] 気管支喘息のモニタリングをめぐって呼気ガス2009
- Author(s)
  長瀬洋之、大田健
- Journal Title
  
  臨床免疫・アレルギー科 52
  
  Pages: 194-8
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production2009
- Author(s)
  Yamamura K, Adachi T, Masuda T, Kojima Y, Hara A, Toda T, Nagase H, Ohta K
- Journal Title
  
  Int Arch Allergy Immunol 149(S1)
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] Intracellular protein phosphorylation in eosinophils and the functional relevance in cytokine production.2009
- Author(s)
  Yamamura K, Adachi T, MasudaT, Kojima Y, Hara A, Toda T, Nagase H, Ohta K
- Journal Title
  
  Int Arch Allergy Immunol 149 S1:
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] An IL-1 cvtokine member IL-33 induces human basophil activation via its ST2 receptor.2008
- Author(s)
  Suzukawa M, Iikura M, Koketsu R, Nagase H, Tamura C, Komiya A, Nakae S, Matsushima K, Ohta K, Yamamoto K, Yamaguchi M.
- Journal Title
  
  J Immunol 181
  
  Pages: 5981-5989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor2008
- Author(s)
  Suzukawa M, Iikura M, Koketsu R, Nagase H, Tamura C, Komiya A, Nakae S, Matsushima K, Ohta K. Yamamoto K, Yamaguchi M
- Journal Title
  
  J Immunol 181
  
  Pages: 5981-5989
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590934
[Journal Article] The role of platelet-derived growth factor receptor in eotaxin signaling of eosinophils.2006
- Author(s)
  Adachi T, Hanaka S, Yano T, Yamamura K, Toshihara H, Nagase H, Chihara J, Ohta K
- Journal Title
  
  Int Arch Allergy Immunol 140(suppl 1)
  
  Pages: 28-34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591044
[Journal Article] The role of platelet-derived growth factor receptor in eotaxin signaling of eosinophils.2006
- Author(s)
  Adachi T, Hanaka S, Yano T, Yamamura K, Yoshihara H, Nagase H, Chihara J, Ohta K
- Journal Title
  
  Int Arch Allergy Immunol 40(suppl 1)
  
  Pages: 28-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591044
[Journal Article] Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells.2004
- Author(s)
  Adachi T, Cui C-H, Kanda A, Kayaba H, Ohta K, Chihara J
- Journal Title
  
  Biochem Biophys Res Commun 320
  
  Pages: 292-296
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591044
[Journal Article] Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells2004
- Author(s)
  Adachi T, Cui C-H, Kanda A, Kayaba H, Ohta K, Chihara J.
- Journal Title
  
  Biochem Biophys Res Commun 320
  
  Pages: 292-296
- Data Source
  KAKENHI-PROJECT-15591044
[Journal Article] The role of platelet-derived growth factor receptor in eotaxin signaling of eosinophils
- Author(s)
  Adachi T, Hanaka S, Yano T, Yamamura K, Yoshihara H, Nagase H, Chihara J, Ohta K
- Journal Title
  
  Int Arch Allergy Immunol (in press)
- Data Source
  KAKENHI-PROJECT-15591044
[Journal Article] 気管支喘息のモニタリングをめぐって呼気ガス
- Author(s)
  長瀬洋之,大田健
- Journal Title
  
  臨床免疫・アレルギー科 52
  
  Pages: 194-198
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 高用量ICS/LABAでコントロール不良な日本人喘息患者を対象としたベンラリズマブの有効性2018
- Author(s)
  大田　健
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09634
[Presentation] EPD2-4 Benralizumab Reduces Exacerbations in Japanese Patients With Severe, Uncontrolled Asthma : Subgroup Analysis of the CALIMA Trial2017
- Author(s)
  Ken Ohta
- Organizer
  第５７回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09634
[Presentation] 慢性副鼻腔炎のポリープ中Mast cellとIgEの分布についての検討2016
- Author(s)
  馬場信太郎, 近藤健二, 鈴川真穂, 大田健, 山岨達也
- Organizer
  日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム（東京・千代田区）
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K20187
[Presentation] ポリープを伴う慢性副鼻腔炎の組織中T細胞分布についての検討2015
- Author(s)
  馬場信太郎、籠谷領二、鈴川圭吾、鈴川真穂、近藤健二、大田健、山岨達也
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京都・港区）
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K20187
[Presentation] Local increase of IgE and class switch recombination to IgE in the nasal polyps in chronic rhinosinusitis2013
- Author(s)
  Shintaro Baba, Kenji Kondo, Makiko Toma-Hirano, Kaori Kanaya, Keigo Suzukawa, Munetaka Ushio, Maho Suzukawa, Ken Ohta and Tatsuya Yamasoba
- Organizer
  The 16th Asian Research Symposium in Rhinology
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24791747
[Presentation] Usefulness of measuring the level of fractional exhaled nitric oxide (FeNO) in various respiratory diseases.2011
- Author(s)
  H Nagase, T Toda, A Kamiyama, Y Nakase, N Sugimoto, H Yoshihara, M Kuramochi, H Tashimo, H Arai, M Yamaguchi, N Suzuki, K Ohta
- Organizer
  2011 American Academy of Allergy Asthma & Immunol Annual Meeting (AAAAI)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] Usefulness of measuring the level of fractional exhaled nitric oxide (FeNO) in various respiratory diseases2011
- Author(s)
  H Nagase, T Toda, A Kamiyama, Y Nakase, N Sugimoto, H Yoshihara, M Kuramochi, H Tashimo, H Arai, M Yamaguchi, N Suzuki, K Ohta
- Organizer
  2011 American Academy of Allergy Asthma & Immunol Annual Meeting (AAAAI)
- Place of Presentation
  San Francisco, USA
- Year and Date
  2011-03-11
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 非喘息性呼吸器疾患における呼気一酸化窒素濃度(FeNO)測定の意義2010
- Author(s)
  戸田貴子,長瀬洋之,神山麻恵,中瀬裕子,杉本直也,鈴川真穂,吉原久直,倉持美知雄,田下浩之,新井秀宜,中野純一,山口正雄,鈴木直仁, 大田健
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] シリカによる慢性肺線維化モデル確立のための長期検討2010
- Author(s)
  原麻恵,長瀬洋之,鈴川真穂,小河原郁子,戸田貴子,小島康弘,倉持美知雄,田下浩之,新井秀宜,山口正雄,鈴木直仁,大田健
- Organizer
  第50回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 呼気一酸化窒素濃度(FeNO)の疾患特異性の検証2010
- Author(s)
  戸田貴子,長瀬洋之,原麻恵,小河原郁子,鈴川真穂,小島康弘,倉持美知雄,田下浩之,新井秀宜,山口正雄,鈴木直仁,大田健
- Organizer
  第50回日本呼吸器学会学術講演会
- Place of Presentation
  京都
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 喘息管理・コントロール状態の評価JGL2009、GINA、EPR3、喘息コントロールテスト(ACT)における喘息コントロール評価の比較2010
- Author(s)
  長瀬洋之,戸田貴子,杉本直也,中瀬裕子,神山麻恵,吉原久直,倉持美知雄,田下浩之,新井秀宜,山口正雄,鈴木直仁,大田健
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 新型インフルエンザと喘息について多面的に考える成人領域における新型インフルエンザの臨床2010
- Author(s)
  長瀬洋之,古賀一郎,太田康男,大田健
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2010-11-27
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] シンポジウム4ウイルス・細菌・真菌とアレルギーS4-5 Innate Immunityとアレルギー2009
- Author(s)
  長瀬洋之,大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] Th17系サイトカインが好酸球からのサイトカイン放出に及ぼす影響2009
- Author(s)
  戸田貴子、長瀬洋之、鈴川真穂、原麻恵、小島康弘、倉持美知雄、田下浩之、新井秀宜、山口正雄、大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] The Effect of Diesel Exhaust Particles on Pathogen-associated Molecular Patterns induced Cytokine Generation from Bronchial Epithelial Cells2009
- Author(s)
  Nagase H,, Takano H, Inoue K, Hara A, Kojima Y, Suzukawa M, Kuramochi M, Ishida H, Adachi T, Suzuki N, Ohta K
- Organizer
  2009 American Academy of Allergy Asthma & Immunol Annual Meeting (AAAAI)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 遺伝子多型と吸入ステロイド(ICS)反応性との関連2009
- Author(s)
  長瀬洋之、釣木澤尚実、原麻恵、松井永子、近藤直実、秋山一男、大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] The relationships between the levels of cytokines and chemokines in exhaled breath condensate and the control status of asthma.2009
- Author(s)
  Hara A, Nagase H, Kojima Y, Suzukawa M, Kuramochi M, Ishida H, Adachi T, Suzuki N, Ohta K
- Organizer
  2009 American Academy of Allergy Asthma & Im munol Annual Meeting (AAAAI)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] International Symposium Session 3 Activation and signaling in inflammatory cells : Expression and Function of Toll-like Receptors in Allergic Inflammatory Cells2009
- Author(s)
  Nagase H, Hirai K, Yamaguchi M, Ohta K
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] The relationships between the levels of cytokines and chemokines in exhaled breath condensate and the control status of asthma2009
- Author(s)
  Hara A, Nagase H, Kojima Y, Suzukawa M, Kuramochi M, Ishida H, Adachi T, Suzuki N, Ohta K
- Organizer
  2009 American Academy of Allergy Asthma & Immunol Annual Meeting (AAAAI)
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] ミニシンポジウム4-#4 喘息治療ステップダウン成功因子としての呼気凝縮液/FeNOの検討2009
- Author(s)
  原麻恵、長瀬洋之、小島康弘、倉持美知雄、田下浩之、新井秀宜、山口正雄、鈴木直仁、工藤宏一郎、小林信之、大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] ミニシンポジウム12-#3 遺伝子多型と吸入ステロイド(ICS)反応性との関連2009
- Author(s)
  長瀬洋之、釣木澤尚実、原麻恵、松井永子、近藤直実、秋山一男、大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] ミニシンポジウム29-#2 Th17系サイトカインが好酸球からのサイトカイン放出に及ぼす影響2009
- Author(s)
  戸田貴子、長瀬洋之、鈴川真穂、原麻恵、小島康弘、倉持美知雄、田下浩之、新井秀宜、山口正雄、大田健
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation]2008
- Author(s)
  中野純一, 足立哲也, 鈴木直仁, 大田健
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20590934
[Presentation] 喘息患者におけるビーズアレイシステムを用いた呼気凝縮液の検討2008
- Author(s)
  小島康弘,長瀬洋之,原麻恵,矢野智湖,鈴川真穂,石田博文,中野純一,足立哲也,鈴木直仁,大田健
- Organizer
  第20回日本アレルギー学会春季臨床大会
- Place of Presentation
  東京
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-20590934
[]
[]
[]

1. NAKANO Jyunichi (20240707)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. NAKAJIMA Mikio (10256034)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. YAMADA Kazuhito (40240006)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YAMASHITA Naomi (20239974)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. BABA Shintaro (90553719)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
6. NAGASE Hiroyuki (40365945)

# of Collaborated Projects: 1 results

# of Collaborated Products: 33 results
7. KONDO Kenji (40334370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. SUZUKAWA Keigo (50447398)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. SUZUKAWA Maho (20453699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. USHIO Munetaka (70361483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. KANAYA Kaori (90456129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. YAMASOBA Tatsuya (60251302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
13. SAWAMOTO Shuichi (30271290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYASAKA Takashi (90312008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ADACHI Tetsuya (30321996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. CHIHARA Junichi (80197615)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. MIYAMOTO Terumasa (80010239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TAKIZAWA Hazime (80171578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. MORITA Yutaka (60107620)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KUDO Koichiro (20107618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ISHII Akira (30272553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 有岡仁 (50297131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 金子富志人 (20328074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 川島隆二

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 野本日出男

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. NAGAI Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 大島信治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OOTA Ken 大田 健

大田 健 オオタ ケン

OHTA Ken 大田 健

Research Projects

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Co-Researchers

Therapeutic effect of alveolar macrophage-specific anti-IGF-1 antibody for idiopathic pulmonary fibrosisPrincipal Investigator

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Molecular biologic approach for clarification of the role of bronchial epithelial cells for development of asthmaPrincipal Investigator

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Mechanisms to induce bronchial asthma - an approach by means of molecular biology clarify how airway hyperresponsiveness is expressed with air pollutants in micePrincipal Investigator

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肺線維症に関与するサイトカインの同定一免疫学的および分子生物学的アプローチPrincipal Investigator

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[Book] アレルギーの臨床 (0285-6379)39巻1号 内服及び吸入用のセフェム系抗菌薬がアナフィラキシーの原因と考えられた一例(原著論文/症例報告)2019

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Total Pages

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[Book] アレルギーの臨床 (0285-6379)38巻9号 「特集/アレルギー疾患における最新の治療」に寄せる 重症喘息の治療コンセプト(解説)2018

Author(s)

Total Pages

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Data Source

OOTA Ken 大田健

大田健オオタケン

OHTA Ken 大田健

[Book] アレルギーの臨床 (0285-6379)39巻1号　内服及び吸入用のセフェム系抗菌薬がアナフィラキシーの原因と考えられた一例(原著論文/症例報告)2019

[Book] アレルギーの臨床 (0285-6379)38巻9号　「特集/アレルギー疾患における最新の治療」に寄せる　重症喘息の治療コンセプト(解説)2018

[Book] 総合診療 (2188-8051)28巻8号　【80歳からの診療スタンダードUp to Date-Silver Standard】80歳以上の高齢者の外来診療　ここがポイント! COPD/喘息診療スタンダードUp to Date(解説/特集)2018

[Book] 保険診療 (0385-8588)73巻7号　こうして医療機関を変えてきた!療養所を母体とする公的病院の一般病院への転換と経営改善への道のり(4)(解説)2018

[Book] アレルギーの臨床 (0285-6379)38巻6号　【アレルギーマーチ予防の考え方】反復する腹痛を主訴とする遺伝性血管性浮腫の1例(原著論文/症例報告/特集)2018

[Book] 保険診療 (0385-8588)73巻6号　こうして医療機関を変えてきた!　療養所を母体とする公的病院の一般病院への転換と経営改善への道のり(3)(解説)2018