SHIMOMURA Yoshiharu 下村吉治

… Alternative Names

下村吉治シモムラヨシハル

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Researcher Number	30162738
Other IDs
Affiliation (Current)	2023: 中部大学, 応用生物学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 中部大学, 応用生物学部, 教授 2010 – 2018: Nagoya University, 生命農学研究科, 教授 2015 – 2016: 名古屋大学, 大学院生命農学研究科, 教授 2008 – 2009: Nagoya University, 大学院・生命農学研究科, 教授 2003 – 2007: 名古屋工業大学, 工学研究科, 教授 … More 1997 – 2004: NAGOYA INST.OF TECHNOL.PROFESSOR, 工学部, 教授 1997: 名古屋大学, 工学部, 教授 1994 – 1996: 名古屋工業大学, 工学部, 助教授 1992: 名古屋工業大学, 保健体育, 助教授 1991: 筑波大学, 体育科学系, 講師 1988: 筑波大学, 体育科学系, 講師 Less
Review Section/Research Field	Principal Investigator Sports science / 体育学 / Food science / Sports science / Environmental physiology (including Physical medicine and Nutritional physiology) / Basic Section 38050:Food sciences-related Except Principal Investigator Digestive surgery / Digestive surgery / 体育学 / Gastroenterology / Integrated Nutrition Science / Gastroenterology
Keywords	Principal Investigator 分岐鎖アミノ酸 / ラット / マウス / 分岐鎖アミノ酸(BCAA) / BCKDHキナーゼ / 分岐鎖α-ケト酸脱水素酵素キナーゼ / 筋肉 / コンディショナルノックアウト / 分岐鎖α-ケト酸脱水素酵素 / BCAA … More / BCKDH複合体 / 肝臓 / OLETFラット / LETOラット / インスリン感受性 / 運動トレーニング / 分岐鎖アミノ酸代謝 / 骨格筋 / 分岐鎖α-ケト酸脱水素酵素(BCKDH) / インスリン抵抗性 / 分岐鎖α-ケト酸脱水素酵素複合体 / 2型糖尿病 / BCAA代謝 / 運動 / 持久力 / IRS-1 / PI3-kinase / 糖尿病 / グルコース代謝 / pyruvate dehydrogenase complex / branched-chain amino acid metabolism / rat / 運動トレ-ニング / 筋ミトコンドリア / ミトコンドリアDNA / クエン酸合成酵素 / チトクロ-ム酸化酵素 / 核DNA / 赤筋と白筋 / 廃用性筋萎縮 / ヒラメ筋 / タンパク質合成促進因子 / ミトコンドリア / 高脂肪食 / 耐糖能 / ロイシン / 後肢懸垂 / 筋タンパク質 / BCAA食 / 総RNA / Zucker diabetic fattyラット / Leanラット / 血漿インスリン / 血漿BCAA / 分岐鎖α一ケト酸脱水素酵素(BCKDH) / コンディショナルBDK-KOマウス / BCAA不足 / キメラマウス / 分岐鎖アミノ酸（BCAA） / 分岐鎖α-ケト酸脱水素酵素（BCKDH） / ES細胞 / BCKDHキナーゼ(BDK) / BDKノックアウト / 筋肉特異的 / Cre-LoxP / 筋 / 神経 / 分岐鎖アミノ酸分解系 / コンディショナルノックアウトマウス / 脳・神経 / 分岐鎖αケト酸脱水素酵素キナーゼ / 分岐鎖アミノ酸分解亢進 / 脂肪組織 / 筋線維タンパク質 / コンディショナルノックアウトノックアウト / 持久走 / 食餌中脂肪酸組成 / 肝臓ミトコンドリア / リン脂質 / 呼吸活性 / チトクローム / カプサイシン / NADH-CoenzymeQ酸化還元酵素 / 女性ホルモン / 食餌タンパク質 / 血清分岐鎖アミノ酸濃度 / 雌雄差 / Branched chain amino acids / Branched-chain alpha-keto acid dehydrogenase / Female hormone / Dietary protein / Exercise training / Rat / Serum branched chain amino acid concentrations / Liver / ピルビン酸脱水素酵素複合体 / グルコース輸送体 / 分岐アミノ酸代謝 / 酵素蛋白質 / mRNA / グルコース輸送体IV / 加齢 / insulin receptor / 遺伝子発現 / exercise training / insulin sensitivity / glucose transporter / 脂肪酸代謝 / ピルビン酸脱水素酵素 / BCKDH kinase / PDH複合体 / PDH kinase / 性差 / クロフィブラート / PPARα / 急性肝炎 / 肝硬変 / 自然発症糖尿病 / 血清遊離脂肪酸 / diabetes / insulin resistance / glucose metabolism / fatty acid metabolism / pyruvate dehydrogenase / branched-chain α-keto acid dehydroqenase / 筋肉痛 / サプリメント / タンパク質合成 / インスリン / スクワット運動 / 培養骨格筋細胞 / siRNA / clofibrate / 血中分岐鎖アミノ酸濃度 / ラット肝臓 / branched-chain amino acids(BCAA) / BCKDH complex / BCAA metabolism / muscle soreness / supplement / protein synthesis / type-2 diabetes / BCKDH / BDK / mTORC1 / 脳神経 / 代謝調節 / ビタミンD / グルココルチコイド / 筋萎縮 / サルコペニア / 筋タンパク質代謝 / ビタミンD欠乏食 … More Except Principal Investigator 肝硬変 / CPT-1 / PPAR-α / 分岐鎖α-ケト酸脱水素酵素複合体 / クロトナーゼ / 3-ヒドロキシイソ酪酸-CoA加水分解酵素 / ヒト肝臓 / ミトコンドリアDNA / NRF-1 / 肝癌 / gastric cancer / c-myc / BCATc / BCATm / BCKDC / Human liver / Mitochondoria / Pyruvate dehydrogenase / PDH kinase / Liver disease / 肝細胞癌 / ミトコンドリア / Cyclin D1 / ウェイトサイクリング / 体脂肪蓄積 / 運動 / ヒト / 肝臓 / 分岐鎖アミノトランスフェラーゼ / バリン / バリン代謝 / クエン酸合成酵素 / 肝炎 / ミトコンドリアRNA / mtTFA / 欠失ミトコンドリアDNA / ミトコンドリアmRNA / NFR-1 / HUMAN LIVER / CIRRHOTIC LIVER / HEPATITIC LIVER / MITOCHONDRIAL DNA / MITOCHONDRIAL RNA / myTFA / DELETION OF MITOCHONDRIAL DNA / c-Myc / ミトコンドリア型分岐鎖アミノ酸アミノ基転移酵素(mBCAT) / 細胞質型分岐鎖アミノ酸アミノ基転移酵素(CBCA) / アイソザイム / ヒト胃粘膜 / 胃癌 / RT-PCR / Methacrylyl-Co A hydratase / β-hydroxyisobutyryl-Co A hydralase / Mito chondria / Pyruvate dehycrogenase / Methacrylyl-CoA hyclratase / β-hyctronyisobutyryl-CoA hyclrolase / Liver diseases / Liver / mitochondria / Methacrylyl-CoA hydratase / β-hydroxyisobutyryl-CoA hydralase / PPAR・α / HEPATOCELLULAR CARCINOMA / MITOCHONDRIA / LIVER CIRRHOSIS / 肝再生 / 再生肝 / Hepatocellular carcinoma / Liver regeneration / Cirrhosis / Mitochondria / 脂肪酸 / 遊離脂肪酸 / 細胞毒性 / 脂肪毒性 / 非アルコール性脂肪性肝炎 / 分岐鎖アミノ酸 / 脂肪肝 / コリン欠乏 / 脂質代謝 Less

Mechanisms responsible for skeletal muscle atrophy induced by vitamin D deficiencyPrincipal Investigator
- Principal Investigator
  
  下村吉治
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Chubu University
Physiological functions of branched-chain amino acids as regulatory factors in mammalsPrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Chubu University
  Nagoya University
Physiological functions of branched-chain amino acids as regulatory factors in mammalsPrincipal Investigator
- Principal Investigator
  
  Shimomura Yoshiharu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Nagoya University
Amino acid nutrition for promoting the efficacy of exercise trainingPrincipal Investigator
- Principal Investigator
  
  Shimomura Yoshiharu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Sports science
- Research Institution
  Nagoya University
Mechanism of amino acid metabolism, alleviation and prevention of hepatic steatosis
- Principal Investigator
  
  Takashi Honda
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
Analysis of lipotoxicity induced by fatty acids
- Principal Investigator
  
  KITAURA Yasuyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Nagoya University
Physiological functions of free branched-chain amino acids in nerve and brainPrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Sports science
- Research Institution
  Nagoya University
PHYSIOLOGICAL FUNCTIONS OF BRANCHED-CHAIN AMINO ACIDS IN MUSCLESPrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Sports science
- Research Institution
  Nagoya University
Effects of amino acid administration and exercise on the regulation of the muscle protein and energy metabolism.Principal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Sports science
- Research Institution
  Nagoya University
肝硬変および癌における代謝状態の改善に関する研究Principal Investigator
- Principal Investigator
  
  下村吉治
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Food science
- Research Institution
  Nagoya University
Effects of amino acid supplementation and exercise on muscle protein synthesisPrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Sports science
- Research Institution
  Nagoya Institute of Technology
Role of PPAR-α on human liver metabolic dysfunction and carcinogenesis
- Principal Investigator
  
  KUROKAWA Tsuyoshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  AICHI MEDICAL UNIVERSITY
Differences in mechanism of regulatory system on energy metabolism between regenerating liver and hepatocellular carcinoma
- Principal Investigator
  
  KOTAKE Katsuhiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Aichi Medical University School of Medicine
Study on the mechanisms responsible for improvement of glucose, lipid, and amino acid metabolism.Principal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nagoya Institute of Technology
Studies of glucose metabolism in human liver disease-influence by mRNA expression for pyruvate dehydrogenase kinase and phosphatse-
- Principal Investigator
  
  NONAMI Toshiaki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  AICHI MEDICAL UNIVERSITY
Study on the mechanisms responsible for improvements of glucose and amino acid metabolism by exercisePrincipal Investigator
- Principal Investigator
  
  SHIMOMURA Yoshiharu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  体育学
- Research Institution
  Nagoya Institute of Technology
Relationship of expression of c-myc and branched-chain aminotransferase in human gastric cancer cells and tissues
- Principal Investigator
  
  GOTO Hidemi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nagoya University
EFFECTS OF CIRRHOTIC LIVER ON MITOCHONDRIAL REPLICATION AND TRANSCRIPTION
- Principal Investigator
  
  NONAMI Toshiaki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  NAGOYA UNIVERSITY
Study on the dietary protein beneficial to the protein synthesis in exercise-trained muscle in rat.Principal Investigator
- Principal Investigator
  
  SHIMOMURA Toshiharu
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  体育学
- Research Institution
  Nagoya Institute of Technology (NIT)
ヒト肝臓におけるバリン代謝の調節:肝硬変による代謝異常のメカニズム
- Principal Investigator
  
  野浪敏明
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya University
ヒト肝臓におけるバリン代謝の調節:肝硬変の影響
- Principal Investigator
  
  NONAMI Toshiaki
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nagoya University
体重の増減の繰り返しが体組成に及ぼす影響とそれに対する運動の効果
- Principal Investigator
  
  鈴木正成
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  体育学
- Research Institution
  University of Tsukuba
運動トレ-ニングによる筋ミトコンドリア増加のメカニズムに関する生化学的研究Principal Investigator
- Principal Investigator
  
  下村吉治
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  体育学
- Research Institution
  University of Tsukuba
ミトコンドリア膜のリン脂質と電子伝達系酵素の相互作用Principal Investigator
- Principal Investigator
  
  下村吉治
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  University of Tsukuba

[Book] アミノ酸の機能特性-ライフサイエンスにおける新しい波-(分担執筆)分担:第1章分岐鎖アミノ酸(BCAA)の代謝調節とサプリメントとしての有用性2007
- Author(s)
  下村吉治
- Publisher
  建帛社
- Data Source
  KAKENHI-PROJECT-17300208
[Journal Article] Antihypertensive drug valsartan as a novel BDK inhibitor.2021
- Author(s)
  Kitaura Y, Shindo D, Ogawa T, Sato A, Shimomura Y.
- Journal Title
  
  Pharmacological Research
  
  Volume: 167 Pages: 105518-105518
- DOI
  10.1016/j.phrs.2021.105518
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02942
[Journal Article] BDK deficiency in cerebral cortex neurons causes neurological abnormalities and affects endurance capacity.2020
- Author(s)
  Mizusawa A, Watanabe A, Yamada M, Kamei R, Shimomura Y, Kitaura Y.
- Journal Title
  
  Nutrients
  
  Volume: 12 Pages: 2267-2267
- DOI
  10.3390/nu12082267
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H02942
[Journal Article] 分岐鎖アミノ酸（BCAA）とインスリン抵抗性2019
- Author(s)
  下村吉治、北浦靖之
- Journal Title
  
  医学と薬学
  
  Volume: 76 Pages: 1595-1601
- Data Source
  KAKENHI-PROJECT-17H03817
[Journal Article] Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex.2018
- Author(s)
  Liang Weng , Yi-Peng Han, Atsushi Enomoto, Yasuyuki Kitaura, Shushi Nagamori, Yoshikatsu Kanai, Naoya Asai, Jian An, Maki Takagishi, Masato Asai, Shinji Mii, Takashi Masuko, Yoshiharu Shimomura, Masahide Takahashi.
- Journal Title
  
  Plos Biology
  
  Volume: 16
- DOI
  10.1371/journal.pbio.2005090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15593, KAKENHI-PROJECT-15H04685, KAKENHI-PROJECT-15H04719, KAKENHI-PROJECT-17H03817, KAKENHI-PROJECT-17H04190, KAKENHI-PROJECT-15K08274, KAKENHI-PROJECT-15K08399, KAKENHI-PROJECT-16K19104, KAKENHI-PROJECT-17K17791, KAKENHI-PROJECT-18H02638, KAKENHI-PROJECT-26221304
[Journal Article] Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions2018
- Author(s)
  Shimomura Yoshiharu、Kitaura Yasuyuki
- Journal Title
  
  Pharmacological Research
  
  Volume: 133 Pages: 215-217
- DOI
  10.1016/j.phrs.2018.05.014
- NAID
  120006554495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03817
[Journal Article] 分岐鎖アミノ酸の分解制御機構とその重要性について2018
- Author(s)
  北浦靖之, 下村吉治
- Journal Title
  
  生化学/公益社団法人日本生化学会
  
  Volume: 90 Pages: 234-237
- NAID
  40021617573
- Data Source
  KAKENHI-PROJECT-17H03817
[Journal Article] Ca2+-dependent inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate2018
- Author(s)
  Noguchi Seisuke、Kondo Yusuke、Ito Rina、Katayama Takahiro、Kazama Shunsuke、Kadota Yoshihiro、Kitaura Yasuyuki、Harris Robert A.、Shimomura Yoshiharu
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 504 Pages: 916-920
- DOI
  10.1016/j.bbrc.2018.09.038
- NAID
  120006554494
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Journal Article] Branched-chain amino acids regulate type I tropocollagen and type III tropocollagen syntheses via modulation of mTOR in the skin2018
- Author(s)
  Yamane T, Morioka Y, Kitaura Y, Iwatsuki K, Shimomura Y, Oishi Y.
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 82 Pages: 611-615
- DOI
  10.1080/09168451.2017.1386084
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07440, KAKENHI-PROJECT-17H03817
[Journal Article] Muscle-specific deletion of BDK amplifies loss of myofibrillar protein during protein undernutrition2017
- Author(s)
  Ishikawa T, Kitaura Y, Kadota Y, Morishita Y, Ota M, Yamanaka F, Xu M, Ikawa M, Inoue N, Kawano F, Nakai N, Murakami T, Miura S, Hatazawa Y, Kamei Y, Shimomura Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 39825-39825
- DOI
  10.1038/srep39825
- NAID
  120006957417
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04926, KAKENHI-PROJECT-15J00645, KAKENHI-PROJECT-26282184, KAKENHI-PROJECT-26291052, KAKENHI-PROJECT-26292068, KAKENHI-PROJECT-26350823, KAKENHI-PROJECT-15K12669, KAKENHI-PROJECT-16K01727, KAKENHI-ORGANIZER-25112001
[Journal Article] Endurance performance and energy metabolism during exercise in mice with a muscle-specific defect in the control of branched-chain amino acid catabolism2017
- Author(s)
  Xu Minjun、Kitaura Yasuyuki、Ishikawa Takuya、Kadota Yoshihiro、Terai Chihaya、Shindo Daichi、Morioka Takashi、Ota Miki、Morishita Yukako、Ishihara Kengo、Shimomura Yoshiharu
- Journal Title
  
  PLOS ONE
  
  Volume: 12
- DOI
  10.1371/journal.pone.0180989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03817
[Journal Article] Branched-chain amino acids alleviate hepatic steatosis and liver injury in choline-deficient high-fat diet induced NASH mice2017
- Author(s)
  Honda T, Ishigami M, Luo F, Lingyun M, Ishizu Y, Kuzuya T, Hayashi K, Nakano I, Ishikawa T, Feng GG, Katano Y, Kohama T, Kitaura Y, Shimomura Y, Goto H, Hirooka Y.
- Journal Title
  
  Metabolism Clinical And Experimental.
  
  Volume: 69 Pages: 177-187
- DOI
  10.1016/j.metabol.2016.12.013
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460998, KAKENHI-PROJECT-15K10998, KAKENHI-PROJECT-17H03817
[Journal Article] mTORC1 is involved in the regulation of branched-chain amino acid catabolism in mouse heart.2016
- Author(s)
  Zhen H, Kitaura Y, Kadota Y, Ishikawa T, Kondo Y, Xu M, Morishita Y, Ota M, Ito T, Shimomura Y.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 6 Pages: 43-49
- DOI
  10.1002/2211-5463.12007
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292068
[Journal Article] Regulation of the plasma amino acid profile by leucine via the system L amino acid transporter.2015
- Author(s)
  Zhen H, Nakamura K, Kitaura Y, Kadota Y, Ishikawa T, Kondo Y, Xu M, Shimomura Y.
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: 79 Pages: 2057-2062
- DOI
  10.1080/09168451.2015.1060845
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292068
[Journal Article] Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats.2015
- Author(s)
  Kadota Y, Toyoda T, Hayashi-Kato M, Kitaura Y, Shimomura Y.
- Journal Title
  
  Metabolism
  
  Volume: 64(9) Pages: 1157-1164
- DOI
  10.1016/j.metabol.2015.05.014
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25504005, KAKENHI-PROJECT-26292068
[Journal Article] Enhanced oleate uptake and lipotoxicity associated with laurate.2015
- Author(s)
  Kitaura Y, Inoue K, Kato N, Matsushita N, Shimomura Y.
- Journal Title
  
  FEBS Open Bio.
  
  Volume: 5 Pages: 485-491
- DOI
  10.1016/j.fob.2015.05.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25504005
[Journal Article] PGC-1α-mediated branched-chain amino acid metabolism in the skeletal muscle2014
- Author(s)
  Y. Hatazawa, M. Tadaishi, Y. Nagaike, A. Morita, Y. Ogawa, O. Ezaki, T. Takai-Igarashi, Y. Kitaura, Y. Shimomura, Y. Kamei*, S. Miura*
- Journal Title
  
  PLoS ONE
  
  Volume: 9
- DOI
  10.1371/journal.pone.0091006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24658120, KAKENHI-PUBLICLY-25126723, KAKENHI-PROJECT-25292076, KAKENHI-PROJECT-25670439, KAKENHI-PROJECT-26282184, KAKENHI-PROJECT-26292068
[Journal Article] Regulation of hepatic branched-chain α-ketoacid dehydrogenase complex in rats fed a high-fat diet2013
- Author(s)
  5. Kadota, Y., Toyoda, T., Kitaura, Y., Adams, S.H., Shimomura, Y.
- Journal Title
  
  Obesity Research & Clinical Practice
  
  Volume: 7 (6)
- DOI
  10.1016/j.orcp.2013.07.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25504005
[Journal Article] Effect of branched-chain amino acid supplementation during unloading on regulatory components of protein synthesis in atrophied soleus muscles.2011
- Author(s)
  Bajotto, G., Sato, Y., Kitaura, Y., Shimomura Y.
- Journal Title
  
  Eur.J.Appl.Physiol. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats.2011
- Author(s)
  Kadota, Y., Kazama, S., Bajotto, G., Kitaura, Y., Shimomura Y.
- Journal Title
  
  J.Parenter.Enteral Nutr. In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Branched-chain amino acid supplementation before squat exercise and delayedonset muscle soreness.2010
- Author(s)
  Shimomura, Y., et al.
- Journal Title
  
  Int.J.Sport Nutr.Exerc.Metab.
  
  Volume: 20 Pages: 236-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Branched-chain amino acid supplementation before squat exercise and delayed-onset muscle soreness.2010
- Author(s)
  Shimomura Y., Inaguma, A., Watanabe, S., Yamamoto, Y., Muramatsu, Y., Bajotto, G., Sato, J., Shimomura, N., Kobayashi, H., Mawatari, K.
- Journal Title
  
  Int.J.Sport Nutr.Exerc.Metab. 20
  
  Pages: 236-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Decreased enzyme activity and contents of hepatic branched-chain α-keto acid dehydrogenase complex subunits in a rat model for type 2 diabetes mellitus.2009
- Author(s)
  Bajotto, G., Murakami, T., Nagasaki, M., Sato, Y., Shimomura Y.
- Journal Title
  
  Metabolism 58
  
  Pages: 1489-1495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate at different potassium ionic levels.2009
- Author(s)
  Akita, K., Fujimura, Y., Bajotto, G., Shimomura Y.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 73
  
  Pages: 1189-1191
- NAID
  10027541478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Modified method for purifying rat liver branched-chain α-ketoacid dehydrogenase complex.2009
- Author(s)
  Fujimura, Y., Muramatsu, Y., Akita, K., Bajotto, G, Shimomura Y.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 73
  
  Pages: 766-768
- NAID
  10027539281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Effects of squat exercise and branched-chain amino acid supplementation on plasma free amino acid concentrations in young women2009
- Author(s)
  Shimomura, Y., et al.
- Journal Title
  
  J.Nutr.Sci.Vitaminol. 55
  
  Pages: 288-291
- NAID
  10025971509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Effects of squat exercise and branched-chain amino acid supplementation on plasma free amino acid concentrations in young women.2009
- Author(s)
  Shimomura Y., Kobayashi, H., Mawatari, K., Akita, K., Inaguma, A., Watanabe, S., Bajotto, G., Sato, J.
- Journal Title
  
  J.Nutr.Sci.Vitaminol. 55
  
  Pages: 288-291
- NAID
  10025971509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] 分岐鎖アミノ酸(BCAA)代謝の調節機構2009
- Author(s)
  下村吉治
- Journal Title
  
  化学と生物 47
  
  Pages: 480-485
- NAID
  10026435927
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Regulation of branched-chain amino acid catabolism in rat models for spontaneous type 2 diabetes mellitus.2008
- Author(s)
  Kuzuya, T., Katano, Y., Nakano, I., Hirooka, Y., Itoh, A., Ishigami, M., Hayashi, K., Honda, T., Goto, H., Fujita, Y., Shikano, R., Muramatsu, Y., Bajotto, G., Tamura, T., Tamura, N., Shimomura Y.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 373
  
  Pages: 94-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] The effects of endotoxin on plasma free amino acid concentrations in rats.2008
- Author(s)
  Asai, Y., Bajotto, G., Yoshizato, H., Hamada, K., Higuchi, T., Shimomura Y.
- Journal Title
  
  J.Nutr.Sci.Vitaminol. 54
  
  Pages: 460-466
- NAID
  110007007844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300216
[Journal Article] Nutraceutical effects of branched-chain amino acids on skeletal muscle.2006
- Author(s)
  Yoshiharu Shimomura, et al.
- Journal Title
  
  Journal of Nutrition 136,2
- Data Source
  KAKENHI-PROJECT-17300208
[Journal Article] Nutraceutical effects of branched-chain amino acids on skeletal muscle.2006
- Author(s)
  Shimomura, Y, et. al.
- Journal Title
  
  Journal of Nutrition 136
  
  Pages: 5295-5325
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300208
[Journal Article] Nutraceutical effects of branched-chain amino acids on skeletal muscle.2006
- Author(s)
  Shimomura, Y., et. al.
- Journal Title
  
  Journal of Nutrition 136
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17300208
[Journal Article] Activation of hepatic branched-chain α-keto acid dehydrogenase complex by tumor necrosis factor-α in rats.2005
- Author(s)
  Shiraki, M., Shimomura, Y., Miwa, Y., Fukushima, H., Murakami, T., Tamura, T., Tamura, N., Moriwaki, H.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 328
  
  Pages: 973-978
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Estrogen controls branched-chain amino acid catabolism in female rats.2004
- Author(s)
  M.Obayashi, Y.Shimomura, et al.
- Journal Title
  
  Journal of Nutrition 134
  
  Pages: 2628-2633
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Downregulation of the skeletal muscle pyruvate dehydrogenase complex in the Otsuka Long-Evans Tokushima fatty rat both before and after the onset of diabetes mellitus.2004
- Author(s)
  Bajotto, G., Murakami, T., Nagasaki, M., Tamura, T., Tamura, N., Harris, R.A., Shimomura, Y., Sato, Y.
- Journal Title
  
  Life Sci. 75
  
  Pages: 2117-2130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Effects of liver failure on the enzymes in the branched-chain amino acid catabolic pathway.2004
- Author(s)
  Shimomura, Y., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 313
  
  Pages: 381-385
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Effects of liver failure on the enzymes in the branched-chain amino acid catabolic pathway.2004
- Author(s)
  Shimomura, Y., Honda, T., Goto, H., Nonami, T., Kurokawa, T., Nagasaki, M., Murakami, T.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 313
  
  Pages: 381-385
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Downregulation of the skeletal muscle pyruvate dehydrogenase complex in the Otsuka Long-Evans Tokushima Fatty rat both before and after the onset of diabetes mellitus.2004
- Author(s)
  G.Bajotto, Y.Shimomura, et al.
- Journal Title
  
  Life Sciences 75
  
  Pages: 2117-2130
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Activation of hepatic branched-chain α-keto acid dehydrogenase complex by tumor necrosis factor-α in rats.2004
- Author(s)
  M.Shiraki, Y.Shimomura, et al.
- Journal Title
  
  Biochemical and Biophysical Research Communications 328
  
  Pages: 973-978
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Effects of liver failure on branched-chain α-keto acid dehydrogenase complex in rat liver and muscle : comparison between acute and chronic liver failure.2004
- Author(s)
  Honda, T., Fukuda, Y., Nakao, I., Katano, Y., Goto, H., Nagasaki, M., Sato, Y., Murakami, T., Shimomura, Y.
- Journal Title
  
  J.Hepatol. 40
  
  Pages: 439-445
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids.2004
- Author(s)
  Y.Shimomura, et al.
- Journal Title
  
  Hepatology Research 30S
- NAID
  10015455326
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids.2004
- Author(s)
  Shimomura, Y., Murakami, T., Nagasaki, M., Honda, T., Goto, H., Kotake, K., Kurokawa, T., Nonami, T.
- Journal Title
  
  Hepatol.Res. 30S
  
  Pages: 3-8
- NAID
  10015455326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Regulation of branched-chain amino acid metabolism and pharmacological effects of branched-chain amino acids.2004
- Author(s)
  Shimomura, Y., et al.
- Journal Title
  
  Hepatol.Res. 30S
  
  Pages: 3-8
- NAID
  10015455326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Journal Article] Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms.2002
- Author(s)
  Kobayashi, R., Murakami, T., Obayashi, M., Nakai, N., Jaskiewicz, J., Fujiwara, Y., Shimomura, Y., Harris, R.A.
- Journal Title
  
  Arch.Biochem.Biophys. 407
  
  Pages: 231-240
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370022
[Presentation] ビタミンD欠乏ラットの骨格筋に対するデキサメタゾン投与の影響2021
- Author(s)
  吉田奈津子、橋村香穂、大井優奈、北浦靖之、下村吉治
- Organizer
  第79回日本栄養・食糧学会中部支部会
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] ラットにおけるBCAA代謝に対するデキサメタゾン投与の影響2021
- Author(s)
  吉田奈津子、橋村香穂、大井優奈、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会第15回学術大会
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] 分岐鎖アミノ酸（BCAA）の多様な生理作用2021
- Author(s)
  下村吉治
- Organizer
  令和３年度日本栄養・食糧学会、日本栄養改善学会「若手フォーラム」
- Invited
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] BCAA代謝を促進すると白色脂肪組織のベージュ化が促進される2021
- Author(s)
  北浦靖之、清河碧、下村吉治
- Organizer
  日本アミノ酸学会第15回学術大会
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] 走運動持久力に対する前脳部特異的 BCAA代謝亢進の影響2020
- Author(s)
  水澤杏南、山田みのり、亀井里奈、下村吉治、北浦靖之
- Organizer
  第74回日本栄養・食糧学会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] BCAA誘発性mTORC1活性化に対する食事組成の影響2020
- Author(s)
  田村友紀、井上智也、下村吉治、北浦靖之
- Organizer
  第14回日本アミノ酸学会学術大会（オンライン開催）
- Data Source
  KAKENHI-PROJECT-20H02942
[Presentation] 筋グリコーゲン代謝に対する分岐鎖アミノ酸(BCAA)の影響2019
- Author(s)
  山田みのり、水澤杏南、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会第１３回学術大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 運動持久力に対する筋特異的分岐鎖アミノ酸(BCAA)分解亢進の影響：筋グリコーゲン代謝とBCAA2019
- Author(s)
  山田みのり、北浦靖之、水澤杏南、山田靖子、鈴木竜成、佐野仁志、下村吉治
- Organizer
  第７３回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 脂肪組織の分岐鎖アミノ酸(BCAA)欠乏による耐糖能への影響2019
- Author(s)
  千田壮志、加賀清美、北浦靖之、下村吉治
- Organizer
  第７３回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Effect of genetically decreased BCAA concentration on glucose tolerance in mice2019
- Author(s)
  Y. Kitaura, S. Senda, Y. Shimomura
- Organizer
  13th Asian Congress of Nutrition (ACN) 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 前頭部興奮性ニューロン特異的BDK欠損マウスの特徴解析2019
- Author(s)
  水澤杏南、山田みのり、下村吉治、北浦靖之
- Organizer
  日本アミノ酸学会第１３回学術大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] The roles of branched-chain amino acids (BCAAs) in regulation of muscle protein metabolism and physical activity2019
- Author(s)
  Y. Shimomura, Y. Kitaura
- Organizer
  7th International Conference on Food Factors (ICoFF) Symposium 55 "Skeletal Muscle Health"
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 筋グリコーゲン量に対する筋特異的分岐鎖アミノ酸(BCAA)分解亢進の影響2019
- Author(s)
  山田みのり, 北浦靖之, 下村吉治
- Organizer
  第23回日本体力医学会東海地方会学術大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 筋グリコーゲン量に対する筋特異的分岐鎖アミノ酸分解亢進の影響2018
- Author(s)
  山田みのり, 北浦靖之, 水澤杏南, 山田靖子, 鈴木竜成, 佐野仁志, 下村吉治
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] マウスの脂肪蓄積に対するBCAA代謝亢進の影響2018
- Author(s)
  加賀清美, 門田吉弘, Jussiaea Bariuan, 千田壮志, 北浦靖之, 下村吉治
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 必須アミノ酸摂取による骨格筋機能改善：分岐鎖アミノ酸(BCAA)の作用を中心として2018
- Author(s)
  下村吉治, 北浦靖之
- Organizer
  第55回日本臨床生理学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Diversity of Physiological Functions of Branched-chain Amino Acids (BCAAs)2018
- Author(s)
  Shimomura Y, Kitaura Y.
- Organizer
  ISTRY2018（第15回国際トリプトファン学会）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 脂肪組織における分岐鎖アミノ酸の欠乏は耐糖能悪化を助長する2018
- Author(s)
  千田壮志, 加賀清美, 北浦靖之, 下村吉治
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 分岐アミノ酸の代謝と生理機能2018
- Author(s)
  下村吉治
- Organizer
  日本アミノ酸学会第12回学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 骨格筋タンパク質合成に対する筋特異的BCAA代謝亢進と低タンパク質食摂取の影響2018
- Author(s)
  山田靖子, 山中郁弥, 佐野仁志, 北浦靖之, 下村吉治
- Organizer
  第72回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 分岐鎖アミノ酸の生理機能の多様性2018
- Author(s)
  下村吉治
- Organizer
  第15回レドックス・ライフイノベーション　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Calcium ion enhances inhibition of the BCKDH kinase by thiamine pyrophosphate (TPP)2018
- Author(s)
  Yoshiharu Shimomura, Seisuke Noguchi, Yasuyuki Kitaura
- Organizer
  NUTRITION 2018（米国栄養学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] 恒常的BCAA分解亢進は運動トレーニング効果にどのように影響するか2017
- Author(s)
  北浦靖之、Xu Minjun、寺井智勇、新土大地、下村吉治
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 恒常的な筋特異的BCAA 分解亢進による筋タンパク質代謝の変化2017
- Author(s)
  山中郁弥, 石川卓弥, 森下由佳子, 山田靖子, 北浦靖之, 下村吉治
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Sports Nutrition for an active life-style.2017
- Author(s)
  Yoshiharu Shimomura
- Organizer
  IUNS 21st International Congress of Nutrition, Symposium144/1028
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Ca2+による分岐鎖アミノ酸代謝の調節2017
- Author(s)
  野口晴右, 伊藤里奈, 近藤雄介, 北浦靖之, 下村吉治
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Diverse functions of branched-chain amino acid (BCAAs)2017
- Author(s)
  Yoshiharu Shimomura
- Organizer
  2017 The Korean Nutrition Society 50th Anniversary International Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] BCAA代謝を調節するビタミンB12017
- Author(s)
  下村吉治
- Organizer
  日本ビタミン学会第69回大会シンポジウム「アミノ酸代謝を調節する補因子研究の最前線」
- Invited
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] マウスのエネルギー代謝に対する脂肪組織特異的分岐鎖アミノ酸代謝の影響2017
- Author(s)
  加賀清美, Jussiaea Bariuan, 千田壮志, 北浦靖之, 下村吉治
- Organizer
  第73回日本栄養・食糧学会中部支部大会
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Adaptability to exercise training and energy metabolism during exercise in mice with muscle-specific deletion of BDK.2017
- Author(s)
  Yoshiharu Shimomura
- Organizer
  Emerging role of Branched-chain Amino Acids in human diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03817
[Presentation] Ca2+とチアミン二リン酸 (TDP)による分岐鎖α-ケト酸脱水素酵素 (BCKDH)キナーゼ (BDK)の不活性化を介した分岐鎖アミノ酸代謝の新たな調節機構2016
- Author(s)
  伊藤里奈、近藤雄介、辻愛、柴田克己、北浦靖之、下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋特異的分岐鎖アミノ酸 (BCAA) 分解亢進による心肥大の誘発2016
- Author(s)
  森下由佳子、北浦靖之、太田美樹、寺井智勇、山中郁弥、下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] マウスの運動トレーニング適応に対する筋特異的分岐鎖アミノ酸(BCAA)分解亢進の影響2016
- Author(s)
  寺井智勇、石川拓弥、北浦靖之、門田吉弘、徐旻裙、新土大地、太田美樹、森下由佳子、田中萌、山中郁弥、下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋特異的BCAA分解亢進による呼吸代謝、体脂肪蓄積への影響2016
- Author(s)
  田中萌、太田美樹、加賀清美、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会10周年記念大会
- Place of Presentation
  東京
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋特異的分岐鎖アミノ酸（BCAA）分解亢進マウスにおける運動による代謝変動2016
- Author(s)
  徐旻裙、寺井智勇、新土大地、森下由佳子、山中郁弥、田中萌、北浦靖之、下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Ca2+による分岐鎖アミノ酸代謝の調節：TPPによる分岐鎖α-ケト酸脱水素酵素キナーゼ阻害に対するCa2+の効果2016
- Author(s)
  野口晴右、伊藤里奈、近藤雄介、門田吉弘、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会10周年記念大会
- Place of Presentation
  東京
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋原繊維タンパク質の維持における分岐鎖アミノ酸代謝制御の重要性2016
- Author(s)
  北浦靖之, 石川卓弥, 森下由佳子, 太田美樹, 徐旻珺, 門田吉弘, 下村吉治
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 糖代謝に対する分岐鎖アミノ酸(BCAA)濃度低下の影響2016
- Author(s)
  太田美樹、北浦靖之、門田吉弘、田中萌、森下由佳子、寺井智勇、下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Effect of adipose specific-promotion of branched chain amino acid (BCAA) catabolism on circulating BCAA concentrations in mice2016
- Author(s)
  Jussiaea Bariuan、Izza Dinalhaque Pranatasari、Minjun Xu、門田吉弘、太田美樹、森下由佳子、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会10周年記念大会
- Place of Presentation
  東京
- Year and Date
  2016-09-11
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋タンパク質代謝の調節における分岐鎖アミノ酸(BCAA)分解制御の重要性2016
- Author(s)
  下村吉治
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  西宮市
- Year and Date
  2016-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Effects of enhanced BCAA catabolism induced by branched-chain alpha-ketoacid dehydrogenase (BCKDH) kinase deficiency on adaptation to exercise training in mice.2015
- Author(s)
  Minjun Xu, Yasuyuki Kitaura, Takuya Ishikawa, Yoshihiro Kadota, Takashi Morioka, Miki Ota, Morishita Yukako, Yoshiharu Shimomura.
- Organizer
  ACN2015（12th Asisn Congress of Nutrition）
- Place of Presentation
  横浜
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560366
[Presentation] Novel Physiological Functions of Branched-chain Amino Acids.2015
- Author(s)
  Yoshiharu Shimomura, Yasuyuki Kitaura, Yoshihiro Kadota.
- Organizer
  ACN2015（12th Asisn Congress of Nutrition）
- Place of Presentation
  横浜
- Year and Date
  2015-05-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] A novel mechanism responsible for regulation of the branched-chain amino acid (BCAA) catabolism: regulation of branched-chain alpha-ketoacid dehydrogenase (BCKDH) kinase by thiamine pyrophosphate.2015
- Author(s)
  Takuya Ishikawa, Yasuyuki Kitaura, Minjun Xu, Yoshihiro Kadota, Miki Ota, Morishita Yukako, Yoshiharu Shimomura.
- Organizer
  ACN2015（12th Asisn Congress of Nutrition）
- Place of Presentation
  横浜
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋の運動適応における分岐鎖アミノ酸の生理機能2015
- Author(s)
  Xu Minjun, 北浦靖之, 石川卓弥, 門田吉弘, 太田美樹, 森下由佳子, 下村吉治
- Organizer
  第70回日本体力医学会大会
- Place of Presentation
  和歌山
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-26560366
[Presentation] 筋特異的分岐鎖アミノ酸（BCAA）分解亢進による心肥大の誘発2015
- Author(s)
  石川卓弥, 北浦靖之, 門田吉弘, 森下由佳子, 太田美樹, 山中郁弥, 下村吉治
- Organizer
  日本アミノ酸学会第９回学術大会
- Place of Presentation
  滋賀
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Oral supplementation of BCAA alleviates hepatic steatosis and liver injury associated with NASH2014
- Author(s)
  Honda T, Ishigami M, Luo F, Ishizu Y, Kuzuya T, Hayashi K, Shimomura Y, Goto H
- Organizer
  AASLD2014
- Place of Presentation
  Boston (USA)
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460998
[Presentation] Characterization of muscle- specific branched-chain a-ketoacid dehydrogenase kinase (BDK)- deficient mice2014
- Author(s)
  Ishikawa, T., Kitaura, Y., Itami, Y., Kadota, Y., Kato, R., Inukai, A., Shimomura, Y
- Organizer
  Experimental Biology 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-28
- Data Source
  KAKENHI-PROJECT-24650406
[Presentation] Physiological functions of branched-chain amino acids (BCAAs) and their safety in food and supplements2014
- Author(s)
  Yoshiharu Shimomura
- Organizer
  ANVISA & ICAAS Workshop on Amino Acids: Safety and quality issues
- Place of Presentation
  ANVISA Conference Room, Brasilia, Brazil
- Year and Date
  2014-08-21
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋特異的分岐鎖アミノ酸代謝亢進マウスの解析2014
- Author(s)
  北浦靖之, 石川卓弥, 伊丹雄也, 加藤里奈, 犬飼彩美, 門田吉弘, 下村吉治
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  川崎市
- Year and Date
  2014-03-29
- Data Source
  KAKENHI-PROJECT-24650406
[Presentation] ラット後肢懸垂による筋萎縮時のタンパク質合成調節因子に対する分岐鎖アミノ酸(BCAA)添加食摂取の影響2010
- Author(s)
  Gustavo Bajotto, 高柳洋、下村吉治
- Organizer
  第65回日本体力医学会大会
- Place of Presentation
  千葉商科大学(千葉県市川市)
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 2型糖尿病モデルラット(ZDFラット)における分岐鎖アミノ酸(BCAA)代謝2010
- Author(s)
  土居崎正雄、下村吉治, 他
- Organizer
  第64回日本栄養・食糧学会大会
- Place of Presentation
  アスティー徳島(徳島県徳島市)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] BCAA代謝に対する高脂肪食摂取の影響2010
- Author(s)
  門田吉弘、北浦靖之、下村吉治
- Organizer
  第64回日本栄養・食糧学会大会
- Place of Presentation
  アスティー徳島(徳島県徳島市)
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 分岐鎖アミノ酸(BCAA)代謝の調節:Branched-chain α-keto acid dehydrogenase (BCKDH) kinaseの不活性化因子2010
- Author(s)
  風間駿輔、白井伸太朗、土本隼、北浦靖之、下村吉治
- Organizer
  日本アミノ酸学会第4回学術集会
- Place of Presentation
  ホテルサンシャイン鬼怒川(栃木県日光市)
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 分岐鎖アミノ酸 (BCAA) の代謝調節と生理機能2009
- Author(s)
  下村吉治
- Organizer
  日本栄養・食糧学会第63回大会
- Place of Presentation
  長崎
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 2型糖尿病モデルラット(ZDF-Fattyラット)における分岐鎖アミノ酸(BCAA)代謝2009
- Author(s)
  土居崎正雄、下村吉治、北浦靖之
- Organizer
  日本アミノ酸学会第3回学術大会
- Place of Presentation
  京都府立大学大学院
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-20658034
[Presentation] Branched-chain alpha-ketoacid dehydrogenase complex (BCKDC) : purification from rat liver and inhibition by thiamin pyrophosphate (TPP)2009
- Author(s)
  下村吉治
- Organizer
  Experimental Biology 2009
- Place of Presentation
  New Orleans, FL, USA
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 分岐鎖アミノ酸(BCAA)の代謝調節と生理機能2009
- Author(s)
  下村吉治
- Organizer
  日本栄養・食糧学会第63回大会
- Place of Presentation
  長崎ブリックホール(長崎市)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] Branched-chain alpha-ketoacid dehydrogenase complex (BCKDC) : purification from rat liver and inhibition by thiamin pyrophosphate (TPP)2009
- Author(s)
  下村吉治, et al.
- Organizer
  実験生物学会EB2009
- Place of Presentation
  米国ニューオリンズ
- Year and Date
  2009-04-20
- Data Source
  KAKENHI-PROJECT-20300216
[Presentation] 分岐鎖アミノ酸(BCAA)代謝に対する中性脂肪投与の影響2007
- Author(s)
  安田優子、永田宏樹、GustavoBajotto, 下村吉治
- Organizer
  第61回日本栄養づ食糧学会大会
- Place of Presentation
  京都
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Effects of branched-chain amino acid(BCAA)supplementation before and afterexercise on delayed-onset muscle soreness(DOMS)and fatigue2007
- Author(s)
  Satoko Watanabe, Asami Inaguma, Gustavo Bajotto, Juichi Sato, HisamineKobayashi, Kazunori Mawatari, andYoshiharu Shimomura
- Organizer
  Experimental Biology 2007
- Place of Presentation
  Washington,DC,USA
- Year and Date
  2007-04-29
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Branched-chain amino acid(BCAA)supplementation attenuates delayed-onsetmuscle soreness induced by squatexercise:pre-exercise vs.post-exercise BCAAmgeshon2007
- Author(s)
  Satoko Watanabe, Asami Inaguma, GustavoB ajotto, Juichi Sato, HisamineKobayashi, Kazunori Mawatari, andYoshiharu Shimomura
- Organizer
  10th Asian Congress of Nutrition
- Place of Presentation
  台北(台湾)
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Effects of endotoxin infusion on plasma amino acid concentrations in rats2007
- Author(s)
  Yosuke Asai, Gustavo Bajotto, HideoYoshizato, Koichiro Hamada, TomokoHiguchi, and Yoshiharu Shimomura
- Organizer
  Experimental Biology2007
- Place of Presentation
  Washington,DC,USA
- Year and Date
  2007-04-29
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Delayed-onset muscle soreness(DOMS) induced by squat exercise is attenuated by branched-chain amino acid(BCAA) supplementation2006
- Author(s)
  Yoshiharu, Shimomura, et. al.
- Organizer
  13th International Conference of Biochemistry of Exercise
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Delayed-onset muscle soreness(DOMS)induced by squat exercise is attenuated by branched-chain amino acid(BCAA)supplementation.2006
- Author(s)
  Yoshiharu Shimomura, et. al.
- Organizer
  13th International Conference of Biochemistry of Exercise
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Nutraceutical effects of branched-chain amino acids on skeletal muscle2005
- Author(s)
  Yoshiharu, Shimomura, et. al.
- Organizer
  International Society of Sports Nutrition
- Place of Presentation
  New Orleans, USA.
- Year and Date
  2005-06-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] Nutraceutical effects of branched-chain amino acids on skeletal muscle.2005
- Author(s)
  Yoshiharu Shimomura, et. al.
- Organizer
  International Society of Sports Nutrition
- Place of Presentation
  New Orleans, USA
- Year and Date
  2005-06-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17300208
[Presentation] マウス骨格筋におけるBCAA代謝の遺伝子発現調節メカニズムの解明
- Author(s)
  畑澤幸乃、只石幹、小川佳宏、北浦靖之、下村吉治、三浦進司、亀井康富
- Organizer
  日本アミノ酸学会第８回学術大会
- Place of Presentation
  東京農業大学
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Effects of muscle-specific promotion of branched-chain amino acid (BCAA) catabolism on growth in mice
- Author(s)
  Yoshiharu Shimomura, Takuya Ishikawa, Yasuyuki Kitaura, Yoshihiro Kadota, Minjun Xu
- Organizer
  36th ESPEN CONGRESS ON CLINICAL NUTRITION & METABOLISM
- Place of Presentation
  Geneva, Switzerland
- Year and Date
  2014-09-06 – 2014-09-09
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 分岐鎖アミノ酸（BCAA）の生理機能とその応用性
- Author(s)
  下村吉治
- Organizer
  第18回日本病態栄養学会年次学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2015-01-10 – 2015-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋肉特異的分岐鎖アミノ酸分解亢進マウスの特徴解析
- Author(s)
  石川卓弥、北浦靖之、徐旻珺、門田吉弘、加藤里奈、下村吉治
- Organizer
  日本アミノ酸学会第８回学術大会
- Place of Presentation
  東京農業大学
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 遺伝子改変による分岐鎖アミノ酸分解亢進マウスにおけるグルコース代謝
- Author(s)
  加藤里奈、門田吉弘、伊丹雄也、石川卓弥、犬飼彩美、徐旻珺、北浦靖之、下村吉治
- Organizer
  第６８回日本栄養・食糧学会大会
- Place of Presentation
  酪農学園大学
- Year and Date
  2014-05-30 – 2014-06-01
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Nutritional Functions of Amino Acids - Focusing on Therapeutic Aspect of Branched-chain Amino Acids
- Author(s)
  Yoshiharu Shimomura
- Organizer
  The 15th National Congress of Indonesian Nutrition Association
- Place of Presentation
  Yogyakaruta, Indonesia
- Year and Date
  2014-11-26 – 2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 筋特異的分岐鎖アミノ酸代謝亢進マウスの解析
- Author(s)
  北浦靖之、石川卓弥、伊丹雄也、加藤里奈、犬飼彩美、門田吉弘、下村吉治
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学（川崎市）
- Data Source
  KAKENHI-PROJECT-24650406
[Presentation] 分岐鎖アミノ酸（BCAA）の生理機能とその応用性
- Author(s)
  下村吉治
- Organizer
  第18回日本病態栄養学会年次学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2015-01-10 – 2015-01-11
- Invited
- Data Source
  KAKENHI-PROJECT-26560366
[Presentation] 分岐鎖アミノ酸代謝亢進による糖・脂質代謝に対する影響
- Author(s)
  北浦靖之、門田吉弘、加藤里奈、太田美樹、石川卓弥、森下由佳子、徐旻珺;、下村吉治
- Organizer
  日本農芸化学会2015年度大会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-26560366
[Presentation] Characterization of muscle-specific branched-chain a-ketoacid dehydrogenase kinase (BDK)-deficient mice
- Author(s)
  Takuya Ishikawa, Yasuyuki Kitaura, Yuya Itami, Yoshihiro Kadota, Rina Kato, Ayami Inukai, Yoshiharu Shimomura
- Organizer
  Experimental Biology 2014
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-04-26 – 2014-04-30
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] 分岐鎖アミノ酸代謝とグルコース代謝の相互作用
- Author(s)
  下村吉治、北浦靖之、門田吉弘、石川卓弥、加藤里
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎シーガイア
- Year and Date
  2014-10-24 – 2014-10-25
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] インスリン抵抗性と分岐鎖アミノ酸(BCAA)代謝
- Author(s)
  下村吉治、北浦靖之、門田吉弘、石川卓弥
- Organizer
  第14回日本抗加齢学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-06-06 – 2014-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-26292068
[Presentation] Nutritional Functions of Amino Acids - Focusing on Therapeutic Aspect of Branched-chain Amino Acids
- Author(s)
  Yoshiharu Shimomura
- Organizer
  The 15th National Congress of Indonesian Nutrition Association
- Place of Presentation
  Yogyakaruta, Indonesia
- Year and Date
  2014-11-26 – 2014-11-29
- Invited
- Data Source
  KAKENHI-PROJECT-26560366

1. KITAURA Yasuyuki (90442954)

# of Collaborated Projects: 9 results

# of Collaborated Products: 70 results
2. NONAMI Toshiaki (80189422)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. MURAKAMI Taro (10252305)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
4. KUROKAWA Tsuyoahi (50291406)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKAGI Hiroshi (70154755)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KADOTA Yoshihiro (10724776)

# of Collaborated Projects: 3 results

# of Collaborated Products: 23 results
7. KOTAKE Katsuhiro (50351101)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
8. 鈴木正成 (90015842)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
9. GOTO Hidemi (10215501)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. 谷口健次

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. NAKAO Akimasa (70167542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJITSUKA Noriaki (60101268)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NIWA Yasumasa (20283442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ARISAWA Tomiyasu (50273230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Takashi Honda (10378052)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. Feng g. g (70351111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 斎藤慎一 (80114081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 長崎大 (30387568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
19. 石上雅敏 (90378042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
20. 津田孝範 (90281568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. NAGAMORI Shushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. ENOMOTO Atsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. OISHI Yuichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 高岸麻紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 金井好克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 浅井直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 三井伸二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 翁良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 高橋雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 亀井康富

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
31. 三浦進司

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
32. 河野史倫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 井上直和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 中井直也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 小川佳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 守田昭仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMOMURA Yoshiharu 下村 吉治

下村 吉治 シモムラ ヨシハル

Research Projects

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Mechanisms responsible for skeletal muscle atrophy induced by vitamin D deficiencyPrincipal Investigator

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Physiological functions of branched-chain amino acids as regulatory factors in mammalsPrincipal Investigator

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Physiological functions of branched-chain amino acids as regulatory factors in mammalsPrincipal Investigator

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Amino acid nutrition for promoting the efficacy of exercise trainingPrincipal Investigator

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Physiological functions of free branched-chain amino acids in nerve and brainPrincipal Investigator

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PHYSIOLOGICAL FUNCTIONS OF BRANCHED-CHAIN AMINO ACIDS IN MUSCLESPrincipal Investigator

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Effects of amino acid administration and exercise on the regulation of the muscle protein and energy metabolism.Principal Investigator

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肝硬変および癌における代謝状態の改善に関する研究Principal Investigator

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Effects of amino acid supplementation and exercise on muscle protein synthesisPrincipal Investigator

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Study on the mechanisms responsible for improvement of glucose, lipid, and amino acid metabolism.Principal Investigator

SHIMOMURA Yoshiharu 下村吉治

下村吉治シモムラヨシハル