OKUNO Kiyotaka 奥野清隆

… Alternative Names

奧野清隆オクノキヨタカ

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Researcher Number	30169239
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2015 – 2017: 近畿大学, 医学部, 教授 2011 – 2013: 近畿大学, 医学部, 教授 2003 – 2005: Kinki University, the medical department, Professor, 医学部, 教授 1999 – 2002: 近畿大学, 医学部, 助教授 1992 – 1998: 近畿大学, 医学部, 講師 1991: 近畿大学, 医学部・第一外科, 講師 1986: Kinki University, 医学部, 講師
Review Section/Research Field	Principal Investigator Digestive surgery Except Principal Investigator Digestive surgery / Digestive surgery
Keywords	Principal Investigator HEPATIC SINUSOIDAL LYMPHOCYTES / IMMUNO-CHEMOTHERAPY / HEPATIC ARTERIAL INFUSION / LIVER METASTASIS / HEPATIC EXTRACTION / INTERLEUKIN-2 / 肝抽出率 / 肝類洞壁細胞 / 免疫化学療法 / 肝動注療法 / 肝転移 / インターロイキン2 … More Except Principal Investigator … More liver metastasis / 大腸癌 / cDNA array / ニューラルネットワーク解析 / 食道癌 / NKT cell / NK activity / Thomsen-Friedenreich antigen / Colon 26 / neuraminidase / 肝転移 / Liposome / Interleukin-2 / CTL / 細胞障害性Tリンパ球 / 細胞障害性T細胞 / CTL反応 / 術後補助療法 / ペプチドワクチン / Tumor-bearing spleen / Metastasis / Lymphokine-activated killer (LAK) cell / Lymphokine-activated killer(LAK)細胞 / Interleukin 2(IL-2) / 癌転移 / 受動免疫療法 / colorectal cancer / neural network / gene expression analysis / 大腸癌肝転移 / ニューラルネットワーク / 遺伝子発現解析 / cDNAアレイ / prognosis / metastasis / esophageal cancer / 遺伝子 / リンパ節転移 / RNA / 予後 / DNAアレイ / 転移 / reservoir function / long-term function / pouchography / evacuation difficulty / colonic J-pouch reconstruction / low anterior resection / rectal cancer / 排便機能 / 低位前方切除 / 経時的変化 / 排便スコアー / 貯留能 / 長期排便機能 / 結腸嚢造影 / 排便困難 / J型結腸嚢再建 / 低位前方切除術 / 直腸癌 / transcriotion factor / glutamine / CTRactivity / liver regeneration / DNAマイクロアレイ / DNA マイクロアレイ / グルタミン / CTL activity / 肝再生 / Thomsen-Friedenreich抗原 / CrypticT抗原 / モノクローナルガラクトース抗体 / Colon26細胞 / Neuraminidase / Liver metastasis / IL-2 clearance / サイトゾ-ル / マウス / インタ-ロイキン2 / 半減期 / サイトゾール / 腎臓 / 生体内代謝 / インターロイキン2 / ガラクト-ス基 / 肝局所免疫 / ガラクトース基 / IL-2代謝 / ヨーロッパ / アメリカ / 免疫治療 / 肝癌ワクチン治療 Less

Clinical trial of peptide vaccination with oral chemotherapy following curative resection for stage III colorectal cancer
- Principal Investigator
  
  KAWAMURA Junichiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kindai University
Peptide-cocktail vaccination for hepatocellular carcinoma
- Principal Investigator
  
  ISHIKAWA Hajime
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University
New classification of digestive system cancers based on gene expression analysis.
- Principal Investigator
  
  SHIOZAKI Hitoshi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University
Analysis of a Comprehensive Gene Expression Profile in Esophageal Squamous Cell Carcinoma by cDNA Microarray
- Principal Investigator
  
  SHIGEOKA Hironori
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University
Functional outcome after anterior resection with ultralow anastomosis for rectal cancer
- Principal Investigator
  
  HIDA Jin-ichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University
Mechanism of liver regeneration from the viewpoints of cytotoxis activity and cell growth factors, and development of a method for enhancement of liver regeneration using glutamine
- Principal Investigator
  
  NAKAI Takuya
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University School
Analysis of liver metastasis mechanism by an antibody to TF antigen
- Principal Investigator
  
  YASUTOMI Masayuki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University School of Medicine
EFFECTS OF INTERLEUKIN-2 VIA HEPATIC ARTERIAL INFUSION ON HEPATIC EXTRACTION AND IMMUNOPOTENTIATIONPrincipal Investigator
- Principal Investigator
  
  OKUNO Kiyotaka
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  KINKI UNIVERSITY,SCHOOL OF MEDICINE
The mechanism of interleukin-2 metabolism and its application for the cancer therapy
- Principal Investigator
  
  YASUTOMI Masayuki
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University School of Medicine
Induction of Tumoricidal Effectors from the Tumor-bearer's Splenocytes and the Prospects of Their Utilization for the Adoptive Immunotherapy
- Principal Investigator
  
  IWASA Zenji, 陣内傳之助
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kinki University

All 2018 2017 2016 2015 2005

All Journal Article Presentation Book

[Book] 治療、免疫療法(編著門田守人、松浦成昭) : 肝転移のすべて2005
- Author(s)
  奥野清隆
- Total Pages
  379
- Publisher
  永井書店(大阪)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Book] 治療、免疫療法:肝転移のすべて((編著)門田守人、松浦成昭)2005
- Author(s)
  奥野清隆
- Total Pages
  379
- Publisher
  永井書店(大阪)
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Multicenter, phase II clinical trial of peptide vaccination with oral chemotherapy following curative resection for stage III colorectal cancer.2018
- Author(s)
  Kawamura J, Sugiura F, Sukegawa Y,Yoshioka Y, Hida JI, Hazama S, Okuno K.
- Journal Title
  
  Oncol Lett.
  
  Volume: 15 Pages: 4241-4247
- DOI
  10.3892/ol.2018.7905
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10153
[Journal Article] Cytotoxic T lymphocyte response to peptide vaccination predicts survival in stage III colorectal cancer.2018
- Author(s)
  Kawamura J, Sugiura F, Sukegawa Y,Yoshioka Y, Hida JI, Hazama S, Okuno K.
- Journal Title
  
  Cancer Sci.
  
  Volume: 印刷中 Issue: 5 Pages: 1545-1551
- DOI
  10.1111/cas.13547
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10153
[Journal Article] MicroRNA-6826 and -6875 in plasma are valuable non invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer.2017
- Author(s)
  Kijima T, Hazama S, Tsunedomi R, Tanaka H, Takenouchi H, Kanekiyo S, Inoue Y, Nakashima M, Iida M, Sakamoto K, Suzuki N, Takeda S, Ueno T, Yamamoto S, Yoshino S, Okuno K, Nagano H.
- Journal Title
  
  Oncology Reports
  
  Volume: 37 Issue: 1 Pages: 23-30
- DOI
  10.3892/or.2016.5267
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10153, KAKENHI-PROJECT-16K10574
[Journal Article] 大腸癌のペプチドワクチン療法2015
- Author(s)
  奥野清隆、杉浦史哲
- Journal Title
  
  日本臨床
  
  Volume: 73 Pages: 579-85
- Data Source
  KAKENHI-PROJECT-15K10153
[Journal Article] Therapy for colonic ileus by obstructive colorectal cancer as an oncologic emergency.2005
- Author(s)
  K.Okuno, J.Hida, E.Ishimaru, K.Ueda, T.Yoshifuji
- Journal Title
  
  Current Therapy 23(9)
  
  Pages: 76-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Number versus distribution in classifying regional lymph node metastases from colon cancer.2005
- Author(s)
  J.Hida, K.Okuno, M.Yasutomi, H.Shiozaki, et al.
- Journal Title
  
  J.Am.Coll.Surg. 201
  
  Pages: 217-222
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Oncology emergencyとしての大腸癌イレウスの治療と問題点2005
- Author(s)
  奥野清隆, 肥田仁一, 石丸英三郎, 上田和毅, 吉藤竹仁
- Journal Title
  
  Current Therapy (カレントテラピー) 23 (9)
  
  Pages: 76-81
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Optimal ligation level of the primary feeding artery and bowel resection margin in colon cancer surgery.2005
- Author(s)
  J.Hida, K.Okuno, M.Yasutomi, H.Shiozaki, et al.
- Journal Title
  
  Dis.Colon Rectum 48(12)
  
  Pages: 2232-2237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Immunological therapy for liver metastasis2005
- Author(s)
  K.Okuno
- Journal Title
  
  Liver Metastasis ((Ed.) M.Monden, N.Matsuura)
  
  Pages: 248-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209044
[Journal Article] Oncology emergencyとしての大腸癌イレウスの治療と問題点2005
- Author(s)
  奥野清隆, 肥田仁一, 石丸英三郎, 上田和毅, 吉藤竹仁
- Journal Title
  
  Current Therapy(カレントテラピー) 23(9)
  
  Pages: 76-81
- Data Source
  KAKENHI-PROJECT-15209044
[Presentation] StageIII大腸癌に対する術後補助ペプチドワクチン療法における細胞障害性T細胞(CVTL)反応の臨床的意義2018
- Author(s)
  川村純一郎，杉浦史哲、助川寧，吉岡康多，肥田仁一，硲彰一，奥野清隆
- Organizer
  第39回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] StageIII大腸癌根治術後患者に対するUFT/LV併用ペプチドワクチン療法-多施設共同第2相臨床試験ー2017
- Author(s)
  川村純一郎，杉浦史哲、助川寧，吉岡康多，肥田仁一，硲彰一，奥野清隆
- Organizer
  第30回日本バイオセラピー学会学術集会総会
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] StageIII大腸癌根治術後患者に対するUFT/LV併用ペプチドワクチン療法の臨床的有効性と安全性の検討-多施設共同第2相臨床試験ー2017
- Author(s)
  川村純一郎，杉浦史哲、助川寧，吉岡康多，肥田仁一，硲彰一，奥野清隆
- Organizer
  第38回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] 進行再発大腸癌に対する 7 種ペプチドワクチンカクテル療法の免疫応答と臨床効果2016
- Author(s)
  杉浦史哲、川村純一郎、助川寧、吉岡康多、肥田仁一、硲彰一、奥野清隆
- Organizer
  第29回日本バイオセラピー学会学術集会
- Place of Presentation
  久留米シティプラザ（久留米市）
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] StageIII大腸癌根治術後患者に対するUFT/LV併用ペプチドワクチン療法の臨床的有効性と安全性の検討2016
- Author(s)
  川村純一郎、杉浦史哲、助川寧、吉岡康多、肥田仁一、硲彰一、奥野清隆
- Organizer
  第29回日本バイオセラピー学会学術集会
- Place of Presentation
  久留米シティプラザ（久留米市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] 化学療法不応進行再発大腸癌に対する7種ペプチドワクチンカクテル療法の臨床試験2015
- Author(s)
  杉浦史哲、吉岡康多、小北晃弘、亀井敬子、吉藤竹仁、川村純一郎、上田和毅、所　忠男、肥田仁一、奥野清隆
- Organizer
  第13回日本臨床腫瘍学会学術集会
- Place of Presentation
  ロイトン札幌(札幌)
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] 7種ペプチドワクチンを用いた進行再発大腸癌に対する2試験の治療成績2015
- Author(s)
  杉浦史哲、小北晃弘、吉岡康多、吉藤竹仁、川村純一郎、上田和毅、所　忠男、肥田仁一、奥野清隆
- Organizer
  第36回癌免疫外科研究会
- Place of Presentation
  奄美観光ホテル(奄美)
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] 進行再発大腸癌に対する7種ペプチドワクチン療法の予後予測因子2015
- Author(s)
  杉浦史哲、吉岡康多、川村純一郎、肥田仁一、奥野清隆
- Organizer
  第28回日本バイオセラピィ学会学術集会
- Place of Presentation
  川越東武ホテル(川越)
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K10153
[Presentation] 治癒切除不能Stage IV大腸癌における予後因子の検討2015
- Author(s)
  所忠男, 奥野清隆, 肥田仁一, 上田和毅, 川村純一郎,大東弘治, 吉藤竹仁, 杉浦史哲
- Organizer
  第13回日本消化器外科学会大会（JDDW2015）
- Place of Presentation
  グランドプリンスホテル新高輪(東京)
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K10153

1. YASUTOMI Masayuki (60028438)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. SHIGEOKA Hironori (70247998)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. SHIOZAKI Hitoshi (70144475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
4. HIROHATA Takeshi (60228848)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IMAMOTO Haruhikoo (80351609)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAI Takuya (60227725)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HIDA Jin-ichi (20238306)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. ISHIKAWA Hajime (90309302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEYAMA Yoshifumi (70263374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TANAKA Akira (60179736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWABE Takashi (70309300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. INUFUSA Haruhiko (30223241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOKORO Tadao (30278676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IWASA Zenji (20111031)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAWAMURA Junichiro (90422948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
16. 中嶋一三 (60227783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中村洋介 (00227951)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大西博昭 (00223892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 中村哲彦 (00159071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 杉浦史哲 (10580631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
21. 西村訓弘

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 陣内傳之助

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. NAKAMURA Tetsuhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OKUNO Kiyotaka 奥野 清隆

奧野 清隆 オクノ キヨタカ

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EFFECTS OF INTERLEUKIN-2 VIA HEPATIC ARTERIAL INFUSION ON HEPATIC EXTRACTION AND IMMUNOPOTENTIATIONPrincipal Investigator

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[Book] 治療、免疫療法(編著 門田守人、松浦成昭) : 肝転移のすべて2005

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[Book] 治療、免疫療法:肝転移のすべて((編著)門田守人、松浦成昭)2005

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[Journal Article] Multicenter, phase II clinical trial of peptide vaccination with oral chemotherapy following curative resection for stage III colorectal cancer.2018

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[Journal Article] Cytotoxic T lymphocyte response to peptide vaccination predicts survival in stage III colorectal cancer.2018

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[Journal Article] MicroRNA-6826 and -6875 in plasma are valuable non invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer.2017

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OKUNO Kiyotaka 奥野清隆

奧野清隆オクノキヨタカ

[Book] 治療、免疫療法(編著門田守人、松浦成昭) : 肝転移のすべて2005