OGUCHI Toshio 小口敏夫

Researcher Number	30169255
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 教授
Affiliation (based on the past Project Information) *help	2017 – 2018: 山梨大学, 大学院総合研究部, 教授 2014 – 2016: 山梨大学, 総合研究部, 教授 2011 – 2013: 山梨大学, 医学部附属病院, 教授 2002: University of Yamanashi, Faculty of Medicine, Professor, 医学部, 教授 2001: 千葉大学, 大学院・薬学研究院, 助教授 … More 2000: 千葉大学, 薬学部, 助教授 1998: Chiba University Faculty of Pharmaceutical Sciences, Assosiate Professor, 薬学部, 助教授 1997: 千葉大学, 医学部, 助教授 1996: Chiba University, Faculty of Pharmaceutical Sciences, Associate Professor, 薬学部, 助教授 1995: 千葉大学, 薬学部, 講師 1991 – 1992: 千葉大学, 薬学部, 講師 Less
Review Section/Research Field	Principal Investigator Physical pharmacy / Medical pharmacy Except Principal Investigator Physical pharmacy / Medical pharmacy
Keywords	Principal Investigator 結晶性 / メカニズム / 医薬品 / ラジカルスカベンジャー / 血管痛 / 安定化 / L-システイン / ダカルバジン / アスコルビン酸 / リボフラビン … More / ファモチジン / ROSアッセイ / 光安定化 / 光分解 / Particle Size / Crystallinity / Micronisation / Particle Design / Supercritical Fluid / 微細化 / 固体分散系 / 補集 / 粒子径 / 微粉化 / 粉末医薬品 / 超臨界流体 / surface energetics / water vapor sorption / polymorph / crystallinity / surface / solid pharmaceutics / interaction / moisture / 吸着熱 / コール酸 / 水和物 / アモルファス / 結晶 / 吸着 / 水 / 表面エネルギー / 水蒸気吸着等温線 / 多形 / 表面状態 / 固体医薬品 / 相互作用 / 水分 / 電子お薬手帳 / プラットフォーム / データ抽出 / レセプトコンピュータ / 薬歴管理 / 電子おくすり手帳 / 診療情報共有 / 診療情報 / インターネット / 処方情報 / 地域連携 … More Except Principal Investigator molecular interaction / mechanochemistry / 包接化合物 / 分子間相互作用 / porous / enantiotropic / cholic acid / sealed-heating / crystal / pharmaceutics / 熱分析 / 密封加熱法 / 溶出 / 非晶質化 / 粉末X線回折 / 固形製剤 / コール酸 / 多孔性 / 光学活性 / コール電子 / 密封加熱 / メカノケシストリー / 結晶 / 製剤工学 / solid dispersion / infrared spectrum / fluorescence / crystallinity / inclusion / cyclodextrin / 非晶質 / メカノケミストリ- / 固体分散系 / 赤外吸収スペクトル / 蛍光スペクトル / 結晶性 / 包接 / シクロデキストリン / メカノケミストリー / カラギーナン / ポリエチレンオキサイド / ガンマ線 / 緩和医療 / 水溶性高分子 / 疼痛緩和 / 末梢神経障害 / 電子線 / ハイドロゲル Less

Study on the Photodegradable Risks of Pharmaceuticals and the Novel Stablizing Technique.Principal Investigator
- Principal Investigator
  
  OGUCHI Toshio
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Yamanashi
Study on Developing Regional-Sharing of Drug-Administrating Information as a Purpose of Realizing "DOKODEMO MY-BYOUIN (My Hospital Anywhere)" PlanPrincipal Investigator
- Principal Investigator
  
  OGUCHI Toshio
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Yamanashi
Characterization of Radiation-modified Hydrogel based on Methylcellulose, Hydroxypropylcellulose and Hydroxypropylmethylcellulose
- Principal Investigator
  
  HANAWA Takehisa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Science
  University of Yamanashi
Characterization for Pharmaceutical Solid Dispersion Prepared by means of Supercritical Carbon DioxidePrincipal Investigator
- Principal Investigator
  
  OGUCHI Toshio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  University of Yamanashi, Faculty of Medicine
  Chiba University
Effects of crystallinity and surface energetic of solid pharmaceuticals on the interaction with moisturePrincipal Investigator
- Principal Investigator
  
  OGUCHI Toshio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University
Analysis of Molecular Interactions in Solid Pharmaceuticals
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University
A Study of Mechanochemical Effects on the Solid Dispersion of Pharmaceuticals and Molecular Interactions
- Principal Investigator
  
  YAMAMOTO Keiji
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Chiba University

All 2019 2018 2017 2016 2015 2013 2012 2011

All Journal Article Presentation

[Journal Article] Photochemmically Stabilized Formulation of Dacarbazine with Reduced Production of Algogenic Photodegradants2019
- Author(s)
  A. Uchida, H. Ohtake, Y. Suzuki, H. Sato, Y. Seto, S. Onoue, T. Oguchi
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 印刷中 Pages: 492-498
- DOI
  10.1016/j.ijpharm.2019.04.063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08399, KAKENHI-PROJECT-19K07225, KAKENHI-PROJECT-18K14948
[Journal Article] Photochemical Mechanism of Riboflavin-Induced Degradation of Famotidine and a Suggested Pharmaceutical Strategy for Improving Photostability2016
- Author(s)
  A. Uchida, S. Onoue, H. Ohotake, Y. Seto, T. Teramatsu, T. Terajima, T. Oguchi
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 105 Issue: 2 Pages: 741-746
- DOI
  10.1002/jps.24689
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08399
[Journal Article] 空気押出型ゼリー剤の試飲調査（第2報）2013
- Author(s)
  花輪剛久，徳武　昇，小口敏夫
- Journal Title
  
  医療薬学
  
  Volume: ３９（１１） Pages: 650-659
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590178
[Journal Article] 持続的血液濾過透析施行患者におけるテイコプラニンのタンパク結合率の変動-低アルブミン血症患者との比較ー2013
- Author(s)
  柳本洋美、寺松剛、後藤順子、柳沢政彦、針井則一、鈴木正彦、花輪剛久、松田兼一、小口敏夫
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 133(6) Pages: 711-717
- NAID
  130003361964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590178
[Journal Article] 空気押し出し型ゼリー剤の試飲調査(第1報)2012
- Author(s)
  花輪剛久、徳武昇、小口敏夫
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 132(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590178
[Journal Article] Formulation study on retinoic acid gel composed of iota-carrageenan, polyethylene oxide and Emulgen® 4082012
- Author(s)
  Keishi Kawata,Takehisa Hanawa, Naoko Endo, Masahiko Suzuki, Toshio Oguchi
- Journal Title
  
  Chem.Pharm.Bull.,
  
  Volume: 60 Pages: 825-830
- NAID
  130001852486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590178
[Journal Article] Formulation Study on Retinoic Acid Gel Composed of Iota-Carrageenan, Polyethylene Oxide and Emulgen® 4082012
- Author(s)
  K. Kawata, T. Hanawa, N. Endo, M. Suzuki, T. Oguchi
- Journal Title
  
  Chem. Pharm. Bull
  
  Volume: 60(7) Pages: 825-830
- NAID
  130001852486
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] Photochemically Stabilized Formulation of Dacarbazine with Reduced Production of Algogeric Photodegradants2018
- Author(s)
  A. Uchida, H. Ohtake, Y. Suzuki, H. Sato, Y. Seto, S. Onoue, T. Oguchi
- Organizer
  AAPS 2018 Pharmsci 360
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08399
[Presentation] 臨床ニーズ解決に向けた新規ストラテジーとしての医薬品製剤の光安定化手法2018
- Author(s)
  内田淳、佐藤秀行、世戸孝樹、尾上誠良、小口敏夫
- Organizer
  第27回DDSカンファレンス
- Data Source
  KAKENHI-PROJECT-16K08399
[Presentation] 血管痛誘発物質産生抑制を指向したダカルバジンの光安定性改善手法の開発2017
- Author(s)
  内田淳、大竹啓斗、鈴木友季子、佐藤秀行、世戸孝樹、尾上誠良、小口敏夫
- Organizer
  日本薬剤学会第32年会
- Place of Presentation
  大宮ソニックシティ（埼玉県・大宮市）
- Year and Date
  2017-05-11
- Data Source
  KAKENHI-PROJECT-16K08399
[Presentation] 血管痛発現リスク軽減を指向したダカルバジンの光安定性改善手法の開発2016
- Author(s)
  内田淳、大竹啓斗、鈴木友季子、佐藤秀行、世戸孝樹、尾上誠良、小口敏夫
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K08399
[Presentation] インターネットを基盤とした地域薬剤関連情報共有システムの構築2015
- Author(s)
  寺松剛、寺島朝子、丹沢彩乃、石田昭義、豊岡坑一、小野俊治、柏木賢治、小口敏夫
- Organizer
  第25回日本医療薬学会年会
- Place of Presentation
  神奈川県・横浜市
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-25460207
[Presentation] Preparation and Characterization of Radiation-modified Hydrogel based on Methylcellulose, Hydroxypropylcellulose and Hydroxypropylmethylcellulose2013
- Author(s)
  T. Hanawa, T. Iijima, T. Oguchi, A. Hiroki, M. Taguchi
- Organizer
  AAPS annual meeting
- Place of Presentation
  San Antonio
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] 空気押し出しゼリー剤の試飲調査(II)2013
- Author(s)
  花輪剛久、徳武昇、小口敏夫
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] Preparation and Characterization of Radiation-modified Hydrogel based on Methylcellulose, Hydroxypropylcellulose and Hydroxypropylmethylcellulose2013
- Author(s)
  T. HANAWA, M. HARASHIMA, Y. KAWANO, F. KAIHO, T. NAKAZWA, T. IIJIMA, T. OGUCHI, A. HIROKI, M. TAGUCHI
- Organizer
  AAPS2013
- Place of Presentation
  San Antonio, USA
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] 末梢性神経痛緩和を目的とした新規外用製剤の開発-第2報-2011
- Author(s)
  花輪和己、花輪剛久、鈴木正彦、小口敏夫
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] ガンマ線照射によるポリエチレンオキサイドーιーカラギーナンハイドロゲルの調製と評価（１）2011
- Author(s)
  河田圭司、花輪剛久、飯島哲也、田口光正、廣木章博、小口敏夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡（静岡）
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] ガンマ線架橋による新規ハイドロゲルの調製と新規素材としての可能性2011
- Author(s)
  河田圭司、花輪剛久、廣木章博、田口光正、鈴木正彦、小口敏夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  靜岡
- Data Source
  KAKENHI-PROJECT-23590178
[Presentation] ガンマ線照射によるポリエチレンオキサイドーιーカラギーナンハイドロゲルの調製と評価（2）2011
- Author(s)
  河田圭司、花輪剛久、飯島哲也、田口光正、廣木章博、小口敏夫
- Organizer
  日本医療薬学会第21年会
- Place of Presentation
  神戸国際会議場（神戸）
- Data Source
  KAKENHI-PROJECT-23590178

1. YAMAMOTO Keiji (50110341)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. YONEMOCHI Etsuo (40201090)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HANAWA Takehisa (00302571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. IIJIMA Tetsuya (70324209)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. TAGUCHI Mitsumasa (60343943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. HIROKI Akihiro (10370462)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. KASHIWAGI Kenji (30194723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. NAKAJIMA Shinichiro (80009175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TOZUKA Yuichi (50312963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ONOUE Satomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results

OGUCHI Toshio 小口 敏夫

Research Projects

Research Products

Co-Researchers

Study on the Photodegradable Risks of Pharmaceuticals and the Novel Stablizing Technique.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on Developing Regional-Sharing of Drug-Administrating Information as a Purpose of Realizing "DOKODEMO MY-BYOUIN (My Hospital Anywhere)" PlanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of Radiation-modified Hydrogel based on Methylcellulose, Hydroxypropylcellulose and Hydroxypropylmethylcellulose

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization for Pharmaceutical Solid Dispersion Prepared by means of Supercritical Carbon DioxidePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of crystallinity and surface energetic of solid pharmaceuticals on the interaction with moisturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of Molecular Interactions in Solid Pharmaceuticals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Study of Mechanochemical Effects on the Solid Dispersion of Pharmaceuticals and Molecular Interactions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Photochemmically Stabilized Formulation of Dacarbazine with Reduced Production of Algogenic Photodegradants2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Photochemical Mechanism of Riboflavin-Induced Degradation of Famotidine and a Suggested Pharmaceutical Strategy for Improving Photostability2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 空気押出型ゼリー剤の試飲調査（第2報）2013

Author(s)

Journal Title

Data Source

[Journal Article] 持続的血液濾過透析施行患者におけるテイコプラニンのタンパク結合率の変動-低アルブミン血症患者との比較ー2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 空気押し出し型ゼリー剤の試飲調査(第1報)2012

Author(s)

Journal Title

Data Source

[Journal Article] Formulation study on retinoic acid gel composed of iota-carrageenan, polyethylene oxide and Emulgen® 4082012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Formulation Study on Retinoic Acid Gel Composed of Iota-Carrageenan, Polyethylene Oxide and Emulgen® 4082012

Author(s)

Journal Title

NAID

Data Source

[Presentation] Photochemically Stabilized Formulation of Dacarbazine with Reduced Production of Algogeric Photodegradants2018

OGUCHI Toshio 小口敏夫