Okumura Katsuzumi 奥村克純

… Alternative Names

奥村克純オクムラカツズミ

OKUMURA Katsuzumi 奥村克純

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Researcher Number	30177183
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Affiliation (Current)	2025: 三重大学, 生物資源学研究科, 招へい教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 三重大学, 生物資源学研究科, 招へい教授 2019 – 2021: 三重大学, 生物資源学研究科, 教授 2011 – 2014: 三重大学, 生物資源学研究科, 教授 2012 – 2013: 三重大学, 大学院・生物資源学研究科, 教授 2010: 三重大学, 大学院・生物資源学研究科, 教授 … More 2007 – 2008: Mie University, 大学院・生物資源学研究科, 教授 2006: 三重大学, 大学院生物資源学研究科, 教授 2004 – 2005: Mie University, Faculty of Bioresources, Professor, 生物資源学部, 教授 1992 – 2004: 三重大学, 生物資源学部, 助教授 1991: Mie University, Faculty of Bioresources, Assistant Professor, 生物資源学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / 応用微生物学・応用生物化学 / Applied molecular and cellular biology / Basic Section 38060:Applied molecular and cellular biology-related / Applied molecular and cellular biology / Applied biochemistry / Structural biochemistry Except Principal Investigator 応用生物化学・栄養化学 / Basic Section 56020:Orthopedics-related / 遺伝 … More / 応用微生物学・応用生物化学 / Applied molecular and cellular biology / Applied biochemistry / Pediatrics Less
Keywords	Principal Investigator FISH / DNA複製 / DNA replication / エピジェネティクス / クロマチン / 複製フォーク / 核マトリックス / セントロメア / ヘテロクロマチン / 染色体 … More / DNA損傷 / DNAメチル化 / 動物細胞 / DNA fiber / 転写 / ES細胞 / エピジェネティック / DNAファイバー / 可視化 / 細胞核 / 複製タイミング / ヒストン修飾 / セントロメアヘテロクロマチン / 核マトリクス / ゲノム / レプリコン / 複製ファクトリー / インプリンティング / 分子コーミング / チェックポイント / Chromatin structure / Bromodeoxyuridine / Replicon / MHC / ヒストンアセチル化 / GC content / 細胞分化 / 発生・分化 / PARP / HSP70 / アセチル化 / heterochromatin / 染色体バンド構造 / Genomic imprinting / SNRPN / Histone acetylation / Gene mapping / replication timing / AS / PWS / Igf2r / genomic imprinting / 蛍光in situハイブリダイゼーション / 染色体構築原理 / 哺乳類染色体 / centromeric heterochromatin / nuclear matrix / visualization / epigenetics / chromatin structure / ゲノム・インプリンティング / Heterochromatin / Nuclear matrix / DNA methylation / gene silencing / Chromosome territory / intranuclear structure / genome imprinting / ヒストン脱アセチル化 / 一次転写産物 / インプリント遺伝子 / intranuclear structures / chromosome structure / Chromosome structure / Chromosoirc Structure / 核内配置 / ゼブラフィッシュ / 遺伝子発現 / 5-aza-2'-deoxycytidine / DNAのメチル化 / クロマチン構造 / 幹細胞 / 脂肪細胞 / PARP-1 / サブテロメア / テロメア / 複製 / ゲノムチップ / 蛍光標識 / genome structure / 動物細胞ゲノム / 出芽酵母 / 転写装置 / Genonic imprinting / DiGeorge Syndrome / replicon / gene amplification / MDR / YAC / acetylation / banding / chromosome / chromosomal abnormality / image analysis / topoisomerase inhibitor / ゲノムの構造 / 酵母人工染色体 / HLA抗原 / 細胞周期 / 主要組識適合抗原複合体 / 遺伝子導入 … More Except Principal Investigator Refolding / Ovalbumin / mRNA / 腰痛 / DNAのメチル化 / RNAシークエンス / エピジェネティックス / 椎間板 / 細胞周期関連遺伝子 / DNAメチル化 / エピジェネティクス / 椎間板変性 / multi-color FISH / nuclear organization / trinucleotide expansion / chromosome / triple-helix / telomere / centromere / non-B DNA structure / non-B型DNA / トリヌクレオチドリピート / セクショニング顕微鏡 / 分裂間期 / テロメア / 核内配置 / アンチセンス / 遺伝子治療 / セントロメア / テロアテ- / 多色FISH / non-B型構造 / 核内配直 / 染色体DNA / Starch Binding Domain / Random Attack / Isozyme / Kinetics / Calorimetry / Subsite Structure / Domain Structure / Glucoamylase / 等温滴定熱量計 / DSC / デンプン結合ドメイン / ランダムアタック / アイソザイム / 反応速度論 / 熱測定 / サブサイト構造 / ドメイン構造 / グルコアミラーゼ / Disulfide bond / Glycoprotein / Protein Disulfide-isomerase / モノクロ-ナル抗体 / 蛋白質糖鎖の役割 / 蛋白質の高次構造形成 / ジスルフィド結合の再形成 / オボアルブミン / ジスルフィド結合 / 糖蛋白質 / Protein Disulfideーisomerase / 品質管理 / RNA / 品質管理因子 / 次世代シークエンサ / 複合体形成 / mRNA輸送体 / 複合体 / 輸送体 / 核外輸送 / Pader-Willi症候群 / SNRPN / Prader-Willi症候群 / 血液サンプル / XIST / SNRRN / 診断法 / 臨床検査 / 染色体機能 / RNA FISH / 選択的化学療法 / MTAP遺伝子 / 癌抑制遺伝子 / p16遺伝子 / 9p21欠失 / HLA抗原 / 細胞周期 / 主要組織適合抗原複合体 / DNA複製 / ジヒドロ葉酸還元酵素 / 蛍光in situハイブリダイゼーション Less

Elucidation of the construction principle of animal cell chromosomes and their control mechanismPrincipal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38060:Applied molecular and cellular biology-related
- Research Institution
  Mie University
Epigenome-wide association study of human intervertebral disc degeneration
- Principal Investigator
  
  Akeda Koji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Mie University
Basic study on the network of mRNA maturation process by analyzing diversified mRNA exporter.
- Principal Investigator
  
  MASUDA Seiji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied biochemistry
- Research Institution
  Kyoto University
Regulation of intranuclear arrangement of genes and construction of cells which highly express recombinant proteinsPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Mie University
Analysis of the molecular basis for mRNA dynamics in the nucleus using next generation sequencer and the function for the factor(s)of quality control.
- Principal Investigator
  
  MASUDA Seiji
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Kyoto University
General principle and importance of organization of chromosome structures during mammalian development and cell differentiationPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Mie University
動物細胞核内複製・転写時の高次クロマチンダイナミクスPrincipal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
脂肪組織由来幹細胞の分化に伴う核内染色体・クロマチン動態Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Mie University
Principle of organization of chromosome structures during mammalian development and cell differentiationPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Mie University
動物細胞核内複製・転写時の高次クロマチンダイナミクスPrincipal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
ゲノム上の核マトリックス結合部位の網羅的解析とそのダイナミクスPrincipal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
ゲノム機能の次世代への継承に必要なクロマチンドメイン構造とその確立Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
ゲノムのリプログラミングと染色体構築原理Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Mie University
RNA-FISH技術を用いた染色体機能異常症のための萌芽的診断法開発研究
- Principal Investigator
  
  久保田健夫
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  University of Yamanashi
Roles of regulation of DNA replication in genomic imprintingPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied molecular and cellular biology
- Research Institution
  Mie University
動物ゲノムのレプリコン構造解明のためのDNA複製部位可視化法の開発Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Structural biochemistry
- Research Institution
  Mie University
真核細胞ゲノム上の複製ドメイン・レプリコンの複製機序の解明Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1999 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Mie University
Analysis of Intranuclear Communication of Homologous Alleles of Imprinted Genes and TransgenesPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Mie University
染色体9p21異常 -癌にとっての両刃の剣-
- Principal Investigator
  
  登勉
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Mie University
FISHによるマルチレプリコンの複製開始制御機構解析法の確立Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Mie University
ヒト・ゲノムの機能的ドメイン構成の解析ならびにFISHの技術開発Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Mie University
統括して機能的制御を受けるゲノム領域の探索とその遺伝子群の同定Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Identification of Replication Units in Mammalian Genome by Fiber-FISHPrincipal Investigator
- Principal Investigator
  
  OKUMURA Katsuzumi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Mie University
統括して機能的制御を受けるゲノム領域の探索とその遺伝子群の同定Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
動物細胞に導入した巨大遺伝子領域の増幅・発現とその核内挙動の解析Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Mie University
Methods to analyze nuclear organizition of mammalian chromosomes in interphase nuclei
- Principal Investigator
  
  IKEMURA Toshimichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  遺伝
- Research Institution
  NATIONAL INSTITUTE OF GENETICS
FISHによるヒトがん特異的微小欠失・増幅領域同定法の開発Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
Delineation of DNA Replication Timing within MHC Region by FISHPrincipal Investigator
- Principal Investigator
  
  OKURMURA Katsuzumi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Mie University
動物細胞に導入したDNAの増幅と複製の解析Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  Mie University
Domain Structure and Function of Gluoamylase
- Principal Investigator
  
  TANAKA Akiyoshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  MIE UNIVERSITY
蛍光in situハイブリダイゼーション法のDNA複製系解析への導入Principal Investigator
- Principal Investigator
  
  奥村克純
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Mie University
FISH法によるDNA複製開始領域の解析
- Principal Investigator
  
  SHIMABAYASHI Yoshihide
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Mie University
The Role of Sugar Chains on the Protein Refolding
- Principal Investigator
  
  SHIMABAYASHI Yoshihide
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用生物化学・栄養化学
- Research Institution
  Mie University

[Journal Article] 158.Reorganization of the DNA replication landscape during adipogenesis is closely linked with adipogenic gene expression2023
- Author(s)
  Takuya Hayakawa, Asashi Yamamoto, Taiki Yoneda, Sakino Hori, Nanami Okochi, Kazuhiro Kagotani, Katsuzumi Okumura, and Shin-ichiro Takebayashi
- Journal Title
  
  Journal of Cell Science
  
  Volume: 136 Issue: 2
- DOI
  10.1242/jcs.260778
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05503, KAKENHI-PROJECT-23K23862
[Journal Article] Genome-wide Analysis of DNA Methylaton Identifies Differentially Methylated Loci Associated With Human Intervertebral Disc Degeneration.2019
- Author(s)
  Ikuno A, Akeda K, Takebayashi S I, Shimaoka M, Okumura K, and Sudo A.
- Journal Title
  
  PLoS One
  
  Volume: 14 Issue: 9 Pages: e0222188-e0222188
- DOI
  10.1371/journal.pone.0222188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06610, KAKENHI-PROJECT-19K09597, KAKENHI-PROJECT-17K08879
[Journal Article] 染色体複製と高次エピゲノム2012
- Author(s)
  奥村克純
- Journal Title
  
  細胞工学
  
  Volume: 31(8) Pages: 909-916
- URL
  https://mol.medicalonline.jp/archive/search?jo=ab6saikb&vo=31&nu=8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] 核マトリックスとゲノムダイナミクス2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62 Pages: 400-401
- Data Source
  KAKENHI-PROJECT-23658091
[Journal Article] 核内ゲノムダイナミクスの可視化: 細胞核-構造と機能2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62(5) Pages: 500-501
- URL
  http://ej.islib.jp/ejournal/2425101228.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] The histone chaperone FACT maintains replication fork rates2011
- Author(s)
  T.Abe, K.Sugimura, Y.Hosono, Y.Takami, M.Akita, A.Yoshimura, S.Tada, T.Nakayama, H.Murofushi, K.Okumura, S.Takeda, M.Horikoshi, M.Seki & T.Enomoto
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Issue: 35 Pages: 30504-30512
- DOI
  10.1074/jbc.m111.264721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370052, KAKENHI-PROJECT-21370075, KAKENHI-PROJECT-21590059, KAKENHI-PUBLICLY-22113502, KAKENHI-PLANNED-22131002, KAKENHI-PROJECT-22380188, KAKENHI-PROJECT-22790281, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23370065
[Journal Article] 核マトリックスとゲノムダイナミクス: 細胞核-構造と機能2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62(5) Pages: 400-401
- URL
  http://ej.islib.jp/ejournal/2425101185.html
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] 核マトリックスとゲノムダイナミクス2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62 Pages: 400-401
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] 核内ゲノムダイナミクスの可視化2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62 Pages: 500-501
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] 核内ゲノムダイナミクスの可視化2011
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学
  
  Volume: 62 Pages: 500-501
- Data Source
  KAKENHI-PROJECT-23658091
[Journal Article] Cell cycle-dependent accumulation of histone H3.3 and euchromatic histone modifications in pericentromeric heterochromatin in response to a decrease in DNA methylation levels2010
- Author(s)
  K. Sugimura, Y. Fukushima,M. Ishida, S. Ito, M. Nakamura, Y. Mori, K. Okumura
- Journal Title
  
  Exp. Cell Res
  
  Volume: 316(17) Issue: 17 Pages: 2731-2746
- DOI
  10.1016/j.yexcr.2010.06.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380188
[Journal Article] Cyclin A-Cdk1 regulates the origin firing program in mammalian cells2009
- Author(s)
  Katsuno, Y., Suzuki, A., Sugimura, K., Okumura, K., Zineldeen, D. H., Shimada, M., Niida, H., Mizuno, T., Hanaoka, F., and Nakanishi, M.
- Journal Title
  
  Proc. Natl. Acad. Sc. USA 106(9)
  
  Pages: 3184-3189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] PARP-1 ensures regulation fork progression by homologous recombination on damaged DNA2008
- Author(s)
  Sugimura, K., Takebayashi, S., Takeda, S., Taguchi, H., and Okumura, K.
- Journal Title
  
  J. Cell Biol. 183(7)(および表紙)
  
  Pages: 1203-1212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] Hyper-Phosphorylated Retinoblastoma Protein Suppresses Telomere Elongation2008
- Author(s)
  Takemura, M., Sugimura, K., Okumura, K., Limsirichaikul, S., Suzuki, M., Yamada, Y., and Yoshida, S.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 72(2)
  
  Pages: 630-635
- NAID
  10027525010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] 哺乳類細胞における核内ゲノムダイナミクスの可視化技術とその応用展開を目指して2007
- Author(s)
  奥村克純
- Journal Title
  
  三重大学生物資源学部紀要 34号
  
  Pages: 1-14
- NAID
  120001164796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19038013
[Journal Article] 核内クロマチン構造と複製タイミング・フォークの制御2007
- Author(s)
  奥村克純
- Journal Title
  
  実験医学 25巻5号
  
  Pages: 739-746
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] Non-denaturing fluorescence in situ hybridization to find replication origins in a specific genome region on the DNA fiber2007
- Author(s)
  Sugimura, K., Takebayashi, S.-I., Ogata, S., Taguchi, H., and Okumura, K.
- Journal Title
  
  Biosci. Biotechnol. Biochem. 71(2)
  
  Pages: 627-632
- NAID
  10027512234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] 核内クロマチン構造と複製タイミング・フォークの制御2007
- Author(s)
  奥村克純
- Journal Title
  
  実験医学 25巻5号
  
  Pages: 739-746
- Data Source
  KAKENHI-PROJECT-17050011
[Journal Article] 核内クロマチン構造と複製タイミング・フォークの制御. 染色体サイクル制御の分子メカニズム2007
- Author(s)
  奥村克純, 杉村和人, 竹林慎一郎, 齋藤辰朗
- Journal Title
  
  実験医学 25
  
  Pages: 739-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] 哺乳類細胞における核内ゲノムダイナミクスの可視化技術とその応用展開を目指して2007
- Author(s)
  奥村克純
- Journal Title
  
  三重大学生物資源学部紀要 34
  
  Pages: 1-14
- NAID
  120001164796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] Functional characterization of a mammalian transcription factor, Elongin A2007
- Author(s)
  Yasukawa, T., Sugimura, K., Fukuda, M., Yamazaki, K., Kitajima, S., Okumura, K. and Aso, T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 352(1)
  
  Pages: 237-243
- NAID
  120001871681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] 哺乳類細胞における核内ゲノムダイナミクスの可視化技術とその応用展開を目指して2007
- Author(s)
  奥村克純
- Journal Title
  
  三重大学生物資源学部紀要 34号
  
  Pages: 1-14
- NAID
  120001164796
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19658131
[Journal Article] 複製フォーク進行制御のダイナミクス2006
- Author(s)
  杉村和人, 奥村克純
- Journal Title
  
  蛋白質核酸酵素 51
  
  Pages: 2123-2125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] Two-step regulation of Ad4BP/SF-1 gene transcription during feta ladrenal development; initiation by aHox-Pbx1-Prep1 complex and maintenance via autoregulation by Ad4BP/SF-12006
- Author(s)
  Zubair, M., Ishihara, S., Oka, S., Okumura, K. and Morohashi K.
- Journal Title
  
  Mol. Cell. Biol. 26
  
  Pages: 4111-4121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18380198
[Journal Article] 核内クロマチン構造と複製・転写のダイナミクス2005
- Author(s)
  奥村克純
- Journal Title
  
  生化学 77巻3号
  
  Pages: 191-199
- NAID
  10015547935
- Data Source
  KAKENHI-PROJECT-16011226
[Journal Article] 核内クロマチン構造と複製・転写のダイナミクス2005
- Author(s)
  奥村克純
- Journal Title
  
  生化学 77巻3号
  
  Pages: 191-199
- NAID
  10015547935
- Data Source
  KAKENHI-PROJECT-16045206
[Journal Article] Chromatin Dynamics in DNA Replication and Gene Transcription(in Japanese)2005
- Author(s)
  Katsuzumi Okumura
- Journal Title
  
  SEIKAGAKU 77(3)
  
  Pages: 191-199
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Journal Article] 核内クロマチン構造と複製・転写のダイナミクス2005
- Author(s)
  奥村克純
- Journal Title
  
  生化学 77巻3号
  
  Pages: 191-199
- NAID
  10015547935
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Journal Article] 核内クロマチン構造と複製・転写のダイナミクス2005
- Author(s)
  奥村克純
- Journal Title
  
  生化学 77巻3号
  
  Pages: 191-199
- NAID
  10015547935
- Data Source
  KAKENHI-PROJECT-15658107
[Journal Article] クロマチン構造とDNA複製2003
- Author(s)
  奥村克純
- Journal Title
  
  生体の科学 54巻3号
  
  Pages: 185-191
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Journal Article] Visualization of Dynamics of DNA Replication and Transcription in Mammalian Cells(in Japanese)2003
- Author(s)
  Katsuzumi Okumura
- Journal Title
  
  KAGAKU-TO-SEIBUTSU 41(9)
  
  Pages: 511-517
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Journal Article] Chromatin Structure and DNA Replication(in Japanese)2003
- Author(s)
  Katsuzumi Okumura
- Journal Title
  
  SEITAI-NO-KAGAKU 54(3)
  
  Pages: 185-191
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Journal Article] 目で見る複製・転写のダイナミクス2003
- Author(s)
  奥村克純
- Journal Title
  
  化学と生物 41巻9号
  
  Pages: 511-517
- NAID
  10012134594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14360206
[Presentation] CRISPR/Cas9を用いたクロマチンドメイン形成に関わるシスエレメントの探索2023
- Author(s)
  坂本萌、鈴木梨乃、奥村克純、竹林慎一郎
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-21K05503
[Presentation] 動物細胞ゲノムの構造・核内動態とその制御に関する分子細胞生物学的研究2022
- Author(s)
  奥村克純
- Organizer
  日本農芸化学会中部支部第193回例会
- Invited
- Data Source
  KAKENHI-PROJECT-21K05503
[Presentation] CRISPR/Cas9を用いた複製ドメイン形成に関わるシスエレメントの探索2021
- Author(s)
  鈴木梨乃, 高橋沙央里, 奥村克純, 平谷伊智朗, 竹林慎一郎
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K05503
[Presentation] 複製依存的DNA脱メチル化後のDNA損傷誘導機構 -hairpin-bisulfite sequence法によるヘミメチル化レベル解析-2014
- Author(s)
  生野彰宏、吉村健、緒方進、奥村克純
- Organizer
  日本生化学会中部支部第77回例会
- Place of Presentation
  名古屋大学野依記念学術交流会館(名古屋市千種区)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] 受動的DNA脱メチル化に伴うDNA損傷誘導機構の解明2014
- Author(s)
  奥村克純、栗谷健志、生野彰宏、吉村健、来馬啓介、伊藤克
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  明治大学生田キャンパス
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] ゼブラフィッシュ由来細胞を用いたDNA複製の解析2014
- Author(s)
  東山恵理子，栗谷健志，アヴシャル恵理子，田丸浩，緒方進，奥村克純
- Organizer
  日本農芸化学会中部支部第171回例会
- Place of Presentation
  名古屋大学シンポジオン(名古屋市千種区)
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] DNA脱メチル化に伴うDNA損傷機構へのヘミメチル化DNA結合タンパク質UHRF1の関与2014
- Author(s)
  柴田隆豊、吉村健、栗谷健志、緒方進、奥村克純
- Organizer
  日本生化学会中部支部第77回例会
- Place of Presentation
  名古屋大学野依記念学術交流会館(名古屋市千種区)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] DNA低メチル化に伴うDNA損傷誘導機構について－DNAメチル化阻害剤5-aza-2’-deoxycytidine処理によるDNMT1の減少－2014
- Author(s)
  村林雄太、金岡秀明、栗谷健志、緒方進、奥村克純
- Organizer
  日本生化学会中部支部第77回例会
- Place of Presentation
  名古屋大学野依記念学術交流会館(名古屋市千種区)
- Year and Date
  2014-05-24
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] 複製依存的DNA脱メチル化後のDNA損傷機構―hairpin-bisulfite sequence法によるヘミメチル化レベル解析―2013
- Author(s)
  生野彰宏，吉村健，奥村克純
- Organizer
  日本生化学会中部支部例会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] DNMT1 減少時における DNA 損傷及び複製フォーク停止機構2013
- Author(s)
  栗谷健志、来馬啓介、吉村健、奥村克純
- Organizer
  第31回染色体ワークショップ・第12回核ダイナミクス研究会
- Place of Presentation
  足柄下郡箱根町
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] UHRF1は受動的DNA脱メチル化後のDNA損傷誘導に関与する2012
- Author(s)
  杉村和人,杉浦健太,来馬啓介,緒方正人,奥村克純
- Organizer
  第6回日本エピジェネティクス研究会年会
- Place of Presentation
  東京一ツ橋学術総合センター東京都
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] Disturbing the function of the nuclear exosome results in the accumulation of adenylated RNA in human nuclei.2012
- Author(s)
  N. Fujiwara, K. Okumura, T. Fujiwara, S. Masuda
- Organizer
  the 4th EMBO meeting
- Data Source
  KAKENHI-PROJECT-23658289
[Presentation] Identification of Damaged DNA Regions Induced by Decreased DNA Methylation Levels ~DNA Methylation Defects might Induce Lifestyle Diseases or Genetic Diseases~2012
- Author(s)
  T. Yoshimura and K. Okumura
- Organizer
  The Fourth International Workshop on Regional Innovation Studies (IWRIS2012)
- Place of Presentation
  Tsu, Japan
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] DNAメチル化レベル低下によりDNA損傷が誘導されるゲノム領域の同定2012
- Author(s)
  吉村健,奥村克純
- Organizer
  日本分子生物学会第35回年会
- Place of Presentation
  福岡国際会議場福岡市
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] UHRF1 is involved in DNA damage induction after passive DNA demethylation2011
- Author(s)
  K. Sugimura, K. Sugiura, H. Nakabayashi, K. Kuruma, M. Ogata, K. Okumura
- Organizer
  The 63rd Annual Meeting of the Japan Society for Cell Biology
- Place of Presentation
  Sapporo
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] 受動的DNA脱メチル化後のDNA損傷誘導にはUHRF1が関与する2011
- Author(s)
  杉村和人,杉浦健太,中林裕貴,来馬啓介,緒方正人,奥村克純
- Organizer
  第5回日本エピジェネティクス研究会年会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] DNAメチル化阻害による転写抑制型クロマチンから転写活性型クロマチンへの転化2011
- Author(s)
  杉村和人,緒方正人,奥村克純
- Organizer
  日本農芸化学会2011年度大会シンポジウム「遺伝子動態解析技術の進歩と発現制御」企画及び講演
- Place of Presentation
  京都市 (震災のため開催中止,要旨集発行)
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] DNMT1ノックダウンによるDNA損傷誘導にはUHRF1が関与する2010
- Author(s)
  杉村和人,杉浦健太,中林裕貴,栗谷健志,緒方正人,奥村克純
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Data Source
  KAKENHI-PROJECT-22380188
[Presentation] PARP-1は相同組換え因子による複製フォーク進行調節を保証する2008
- Author(s)
  杉村和人、竹林慎一郎、武田俊一、奥村克純
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-18380198
[Presentation] DNA低メチル化誘導に伴う染色体不安定化2007
- Author(s)
  伊藤克、杉村和人、奥村克純
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-18380198
[Presentation] Replication-dependent association of Chromatin DNA and replication machinery to the nuclear Matrix2007
- Author(s)
  Saito, T., Ninomiya, K., Ogata, S., Taguchi, H. and Okumura, K.
- Organizer
  International Symposium of Functional Organization of the Nucleus
- Place of Presentation
  Awaji, Japan
- Data Source
  KAKENHI-PROJECT-18380198
[Presentation] 可視化でひもとく核内高次クロマチンダイナミクスの理解とその応用展開を目指して2007
- Author(s)
  奥村克純、齋藤辰朗、杉村和人、緒方進、田口寛
- Organizer
  日本農芸化学会2007年度大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-18380198
[Presentation] Disturbing the function of the nuclear exosome results in the accumulation of adenylated RNA in human nuclei
- Author(s)
  Fujiwara N, Okumura K, Fujiwara T, Masuda S
- Organizer
  the 4th EMBO meeting
- Data Source
  KAKENHI-PROJECT-23380059
[Presentation] Epigenetic abnormalities: DNA damage induction by DNA hypomethylation and the nutritional connection
- Author(s)
  Katsuzumi Okumura
- Organizer
  The 1st International Symposium for Bioengineering Research and Education
- Place of Presentation
  UCSD, Building 1, La Jolla, USA
- Year and Date
  2014-08-04 – 2014-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] The Lack of the Nutrition Ingredient Induces the DNA Damage
- Author(s)
  Yuta Minamigawa and Katsuzumi Okumura
- Organizer
  The Sixth International Workshop on Regional Innovation Studies
- Place of Presentation
  Regional Innovation Hall, Mie University, Tsu, Japan
- Year and Date
  2014-10-16 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] Molecular and Cellular Analysis Using Zebrafish Derived Cells
- Author(s)
  Kenji Kuriya, Eriko Higashiyama, Eriko Avsal, Yutaka Tamaru, Shin Ogata, and Katsuzumi Okumura
- Organizer
  The Sixth International Workshop on Regional Innovation Studies
- Place of Presentation
  Regional Innovation Hall, Mie University, Tsu, Japan
- Year and Date
  2014-10-16 – 2014-10-17
- Data Source
  KAKENHI-PROJECT-23658091
[Presentation] Disturbing the function of the nuclear exosome results in the accumulation of adenylated RNA in human nuclei
- Author(s)
  Fujiwara N, Okumura K, Fujiwara T, Masuda S
- Organizer
  EMBO meeting
- Place of Presentation
  フランス　ニース　アクロポリスコンベンションセンター
- Data Source
  KAKENHI-PROJECT-23380059

1. SUGIMURA Kazuto (90452226)

# of Collaborated Projects: 4 results

# of Collaborated Products: 16 results
2. SHIMABAYASHI Yoshihide (10024530)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SATO Noriko (70280956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MASUDA Seiji (20260614)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. TANAKA Akiyoshi (10155111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKEMURA Toshimichi (50025475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Akeda Koji (20422826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 登勉 (60106995)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 久保田健夫 (70293511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 白髭克彦 (90273854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田口寛 (60024593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 島岡要 (40281133)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 須藤啓広 (60196904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 竹林慎一郎 (50392022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. 栗谷健志 (10835309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAMIYA Kiyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀越正美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okumura Katsuzumi 奥村 克純

奥村 克純 オクムラ カツズミ

OKUMURA Katsuzumi 奥村 克純

Research Projects

Research Products

Co-Researchers

Elucidation of the construction principle of animal cell chromosomes and their control mechanismPrincipal Investigator

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Epigenome-wide association study of human intervertebral disc degeneration

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Basic study on the network of mRNA maturation process by analyzing diversified mRNA exporter.

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Regulation of intranuclear arrangement of genes and construction of cells which highly express recombinant proteinsPrincipal Investigator

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Analysis of the molecular basis for mRNA dynamics in the nucleus using next generation sequencer and the function for the factor(s)of quality control.

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General principle and importance of organization of chromosome structures during mammalian development and cell differentiationPrincipal Investigator

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動物細胞核内複製・転写時の高次クロマチンダイナミクスPrincipal Investigator

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脂肪組織由来幹細胞の分化に伴う核内染色体・クロマチン動態Principal Investigator

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Principle of organization of chromosome structures during mammalian development and cell differentiationPrincipal Investigator

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動物細胞核内複製・転写時の高次クロマチンダイナミクスPrincipal Investigator

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ゲノム上の核マトリックス結合部位の網羅的解析とそのダイナミクスPrincipal Investigator

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ゲノム機能の次世代への継承に必要なクロマチンドメイン構造とその確立Principal Investigator

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ゲノムのリプログラミングと染色体構築原理Principal Investigator

Principal Investigator

Okumura Katsuzumi 奥村克純

奥村克純オクムラカツズミ

OKUMURA Katsuzumi 奥村克純