SEMBA Juni'chi 仙波純一

… Alternative Names

SEMBA Jun'ichi 仙波純一

仙波純一センバジユンイチ

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Researcher Number	30183429
External Links
Affiliation (based on the past Project Information) *help	2005 – 2006: 放送大学, 教養学部, 教授 2000 – 2003: 放送大学, 教養学部, 教授 1993 – 1999: The University of the Air Div. of Health Scences Associate Professor, 教養学部, 助教授 1991: 東京医科歯科大学, 医学部, 助手 1987 – 1988: 東京医科歯科大学, 医学部, 助手 1986: 東京医科歯科大学, 医学部・神経精神医学教室, 助手
Review Section/Research Field	Principal Investigator Psychiatric science / Psychiatric science Except Principal Investigator 内科学一般 / Psychiatric science / Neurology
Keywords	Principal Investigator 動物モデル / 神経発達障害仮説 / 精神分裂病 / セロトニン / うつ病 / 神経発達障害 / animal model / Bcl-2 / Bax / MRS … More / 躁うつ病 / ストレス / 血小板 / 学習無力 / 最早期遺伝子 / 分子生物学 / エストロゲン / IGF-I / カイニン酸 / 神経成長因子 / 神経栄養因子 / メタンフェタミン / 一酸化窒素 / ドーパミンD1受容体 / NEURODEVELOPMENTAL ABNORMALITY / SCHIZOPHRENIA / ANIMAL MODEL / アンチセンス / モデル動物 / hepatocyte / inducible nitric oxide synthase / interleukin 1β / nulear factor-kB / nitric oxide / liver injury / セロトニン・トランスポーター / ノルアドレナリン / ノルアドレナリン・トランスポーター / セロトニン・トランスボーター / 神経発達 / ラット / depression / serotonin / serotonin transporter / noradrenaline / noradrenaline transporter / 統合失調症 / ドーパミン・トランスポーター / アポトーシス / neurodevelopmental disorder / schizophrenia / dopamine transporter / apoptosis … More Except Principal Investigator estrogen / カイニン酸 / Ca^<2+> / in situ hybridization / glucocorticoid / nicotine / dexamethasone / in vivo microdialysis / 海馬 / c-fos / glutamate / 原癌遺伝子 / dopamine / D2受容体 / cyclic AMP / regulatory subunit / catalytic subunit / isothiocyanate / D1 and D2 receptors / mRNA / hepatocyte growth factor / kainic acid / sensor output / glutamate oxidase / glutamine / Estrogen / Insulin-like growth factor / Gel shift assay / AP-1結合活性 / AP-1-DNA binding activity / insulin-like growth factor / dot blotting / HGF / 大脳皮質 / cDNA library / shot-gun PCR / β-estradiol / differential hybridization / cloning / 躁うつ病 / アミンプレカーサー / L-threo-DOPS / L-5HTP / 強制水泳法 / ドパミン受容体 / 線条体 / PI turnover / SCH23390 / コレシストキニン / cerulein / チロジン水酸化酵素 / in vivo dialysis / peptide / D1拮抗剤 / 線条件 / Dopamine系 / D1 / D2 / Pentylenetetrazol / Peptide / ドパミン / ニュ-ロテンシン / ニュ-ロペプタイドY / カルシウムイオン / イノシト-ルリン脂質代謝 / D_1,D_2受容体 / ドパミン放出 / dopamine receptors / striatum / PI trnover / SCH 23390 / CCK / immediate early genes / tyrosine hydroxylase / カルシウムイオン濃度 / 蛍光測光法 / cyclic AMP依存性酵素 / A Kinase / holoenzyme / D1受容体 / 培養神経細胞 / Cyclic AMP / A-kina se / 蛍光標識 / tetramethylrhodamin / fluorescein / catalytic unit / regulatory unit / rhodamine / calcium ion / fluorometry / A kinase / immedeate early gene / 細胞内Ca^<2+> / nothern blotting法 / hepatocyto growth factor(HGF) / steroid hormon / 扁桃核 / セルレイン / Nothern blotting / C-fos / Zif / 268 / ペンチレントラゾール / エストロゲン / immediate early gene / glucocortitoid / nothern blotting / 白金黒sensor / 過酸化水素 / アスコルビン酸 / Ptチューブ / glutamine oxidase / ptチューブ / platinum black sensor / hydrogen peroxide / ascorbic acid / platinum tube / Hepatocyte growth factor / 神経栄養因子 / 神経可塑性 / LDH effluxmetry / 神経細胞栄養因子 / Estrogen受容体 / Hepatocyto growth factor / Neuronal growth factor / Kainic acid / Neuronal plasticity / 免疫組織化学 / ジヒドロピリジン系Ca拮抗薬 / CA^<2+> / Immunohistochemistry / 双極性感情病 / 妄想型分裂病 / 尿中フェニルエチルアミン / 血中MHPG / イミプラミン結合 / パロキセチン結合 / ヒト血小板 / ストレス / 双極感情病 / 5-HT取り込み / ^3H-imipramine結合 / ^3H-paroxetine結合 / うつ病血清 / 除タンパク血清 / 5ーHT取り込み / ^3Hーimipramine結合 / ^3Hーparoxetine結合 / AFFECTIVE DISORDER / PARANOID SCHIZOPHRENIA / BETA-PHENYLETHYLAMINE / IMIPRAMINE BINDING / PAROXETINE BINDING / MONOAMINE OXIDASE Less

Biological mechanisms of pubertal onset of schizophrenia in animal model of rats based on neurodevelopmental hypothesis.Principal Investigator
- Principal Investigator
  
  SEMBA Juni'chi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of the Air
The role of serotonin transporter during neurodevelopment in the formation of biological vulnerability to depressionPrincipal Investigator
- Principal Investigator
  
  SEMBA Jun'ichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of the Air
Animal model of schigophrenia based on the suppression of ganes in postnatal brainPrincipal Investigator
- Principal Investigator
  
  SEMBA Junicih
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  UNIVERSITY OF THE AIR
Development of animal model of schizophrenia based on prenatal brain injuriesPrincipal Investigator
- Principal Investigator
  
  SEMBA Junichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  University of The Air
カイニン酸脳傷害に伴う脳内遺伝子発現に関する研究-スクリーニングと同定-
- Principal Investigator
  
  鬼頭昭三
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Hyogo University
  Showa Women's University
グルコユルチュイドとエストロゲンの神経細胞死と生存に対する影響Principal Investigator
- Principal Investigator
  
  仙波純一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Open University of Japan
神経発達障害説から見た精神分裂病における神経栄養因子の役割Principal Investigator
- Principal Investigator
  
  仙波純一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  The Open University of Japan
Estrogen and neuronal apoptosis -the molecular mechamism-
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  University of the Air
CROSSTALKS AMONG SIGNAL TRANSDUCTION SYSTEMS IN APOPTOSIS IN RELATION WITH DEVELOPMENT DIFFERENTIATION AND AGING
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  University of the Air
エストロジェン、癌遺伝子と神経細胞死
- Principal Investigator
  
  鬼頭昭三
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Open University of Japan
うつ病モデルラットにおける分子生物学的研究-学習無力ラットの脳内最早期遺伝子の発現-Principal Investigator
- Principal Investigator
  
  仙波純一
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  The Open University of Japan
ESTABLISHMENT OF AN ONLINE ASSAY SYSTEM OF INTRACEREBRALLY RELEASED GLUTAMATE BY MEANS OF MICROBIOCENSOR
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  University of the Air
ステロイドホルモンの海馬神経細胞に対するtoxic effectに関する研究
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The Open University of Japan
Molecular mechanism of long-term effects of neurotransmitters
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of the Air
MRSを用いた躁うつ病の臨床的研究Principal Investigator
- Principal Investigator
  
  仙波純一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Medical and Dental University
Three dimentional assay of cyclic nucleotide in cultured cells with use of a confocal system
- Principal Investigator
  
  KITO Shuzo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  THE UNIVERSITY OF THE AIR
Regulatory mechanism of doaminergic signal transduction in the striatum-bichemical studies.
- Principal Investigator
  
  KITO Shozo
- Project Period (FY)
  1990 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内科学一般
- Research Institution
  THE UNIVERSITY OF THE AIR
The Similarities and Differences of Biological Markers in Bipolar Disorders and Paranoid Schizophrenia
- Principal Investigator
  
  WATANABE Akiko, 高橋良
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Medical and Dental University
選択的中枢アミンプレカーサーを用いた躁うつ病の生化学的成因の研究
- Principal Investigator
  
  高橋良
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Tokyo Medical and Dental University

All 2006 2005 2004 2003

All Journal Article

[Journal Article] Different effects of chronic phencyclidine on brain-derived neurotrophic factor in neonatal and adult rat brains.2006
- Author(s)
  Semba, J et al.
- Journal Title
  
  Addiction Biology 11
  
  Pages: 126-130
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Mechanism of adverse effects of antipsychotics2006
- Author(s)
  Semba, J.
- Journal Title
  
  Rinsho Seisin Igaku 35
  
  Pages: 29-35
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Psychopharmacology of partial agonist2006
- Author(s)
  Semba, J.
- Journal Title
  
  Rinsho Seisin Igaku 35
  
  Pages: 369-376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] 抗精神病薬による副作用発現メカニズム.2006
- Author(s)
  仙波純一
- Journal Title
  
  臨床精神医学 35
  
  Pages: 29-35
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Dopamine hypothesis of schizophrenia : its history, present and future.2006
- Author(s)
  Semba, J.
- Journal Title
  
  Rinsho Seisin Yakuri 9
  
  Pages: 171-181
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Different effects of chronic phencyclidine on brain-derived neurotrophic factor in neonatal and adult rat brains.2006
- Author(s)
  Semba, J.
- Journal Title
  
  Addiction Biology (印刷中)
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Different effects of chronic phencyclidine on brain-derived neurotrophic factor in neonatal and adult rat brains.2006
- Author(s)
  Semba, J.
- Journal Title
  
  Addiction Biology 11
  
  Pages: 126-130
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] パーシャルアゴニストの精神薬理2006
- Author(s)
  仙波純一
- Journal Title
  
  臨床精神医学 35
  
  Pages: 369-376
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] 抗精神病薬による副作用発現メカニズム2006
- Author(s)
  仙波純一
- Journal Title
  
  臨床精神医学 35
  
  Pages: 29-35
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] 統合失調症のdopamine仮説の歴史,現状と将来2006
- Author(s)
  仙波純一
- Journal Title
  
  臨床精神薬理 9
  
  Pages: 171-181
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] 統合失調症のdopamine仮説の歴史,現状と将来.2006
- Author(s)
  仙波純一
- Journal Title
  
  臨床精神薬理 9
  
  Pages: 171-181
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] 気分安定薬の統合失調症への適応を探る.2005
- Author(s)
  仙波純一
- Journal Title
  
  精神科治療学 20
  
  Pages: 133-140
- Data Source
  KAKENHI-PROJECT-17591232
[Journal Article] Long-term suppression of methamphetamine-induced c-Fos expression in rat striatum by the injection of c-fos antisense oligodeoxynucleotides absorbed in water-absorbent polymer.2004
- Author(s)
  Semba, J., Wakuta, M., Suhara, T.
- Journal Title
  
  Psychiatry and Clinical Neurosciences 58
  
  Pages: 531-535
- NAID
  10016987619
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats : implications for precipitation of depression during smoking cessation.2004
- Author(s)
  Semba J., Wakuta M., Maeda J., Suhara T.
- Journal Title
  
  Psychoneuroendocrinology 29
  
  Pages: 215-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Comprehensive expression analysis of a rat depression model.2004
- Author(s)
  Nakatani, N., Aburatani, H., Nishimura, K., Semba, J., Yoshikawa, T.
- Journal Title
  
  The Pharmacogenomics Journal 4
  
  Pages: 114-126
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Alterations in the expressions of mRNA for GDNF and its receptors in the ventral midbrain of rats exposed to subchronic phencyclidine.2004
- Author(s)
  Semba, J., Akanuma, N., Wakuta, M., Tanaka, N., Suhara, T.
- Journal Title
  
  Molecular Brain Research 124
  
  Pages: 88-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Long-term suppression of methamphetamine-induced c-Fos expression in rat striatum by the inhection of c-fos antisense oligodeoxynucleotides asorbed in water-absorbent polymer.2004
- Author(s)
  Semba, J
- Journal Title
  
  Psychiatry and Clinical Neuroscience 25
  
  Pages: 531-535
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex.2003
- Author(s)
  Maeda, J., Suhara, T., Okauchi, T., Semba, J.
- Journal Title
  
  Neuroscience Letters 336
  
  Pages: 171-174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570941
[Journal Article] Nicotine withdrawal induces subsensitivity of hypothalamic-pituitary-adrenal axis to stress in rats : implications for precipitation of depression during smoking cessation.2003
- Author(s)
  Semba, J
- Journal Title
  
  Psychoneuroendocrinology 29
  
  Pages: 215-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570941

1. KITO Shozo (00010140)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. MIYOSHI Rie (80209965)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SUHARA Testuya (90216490)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. WATANABE Akiko (40210992)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NANKAI Masahiro (20218069)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. WATANABE Yasuhiro (90127324)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TOHYAMA Masaya (40028593)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 高橋良 (70009918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MAGGI A.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. BARNARD Elic.a.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. JOH Tong h.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. OLSEN Richard w.

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. JOH Tong H

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. NOMURA Yasuyuki (00034041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KANENO Shigeru (90126219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 融道男 (20013972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 福田潤 (50010062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 深間内文彦 (90240746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 新郷明子 (50309499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 野本照子 (20075154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 佐藤公道 (80025709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. TAKETANI Shigeru (20121949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. MAGGI A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. BARNARD E.A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. VENTER Graig

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. GRAIG J.Vent

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. TONG H.Joh

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. RICHARD W.Ol

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. JHO Tong H

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. H.JOH Tong

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. BARNARD E. A

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SEMBA Juni'chi 仙波 純一

SEMBA Jun'ichi 仙波 純一

仙波 純一 センバ ジユンイチ

Research Projects

Research Products

Co-Researchers

Biological mechanisms of pubertal onset of schizophrenia in animal model of rats based on neurodevelopmental hypothesis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of serotonin transporter during neurodevelopment in the formation of biological vulnerability to depressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Animal model of schigophrenia based on the suppression of ganes in postnatal brainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of animal model of schizophrenia based on prenatal brain injuriesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グルコユルチュイドとエストロゲンの神経細胞死と生存に対する影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

神経発達障害説から見た精神分裂病における神経栄養因子の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

うつ病モデルラットにおける分子生物学的研究-学習無力ラットの脳内最早期遺伝子の発現-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

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Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Institution

MRSを用いた躁うつ病の臨床的研究Principal Investigator

Principal Investigator

SEMBA Juni'chi 仙波純一

SEMBA Jun'ichi 仙波純一

仙波純一センバジユンイチ