SAKAMOTO Atsuhiro 坂本篤裕

Researcher Number	30196084
Other IDs
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Affiliation (based on the past Project Information) *help	2016 – 2023: 日本医科大学, 大学院医学研究科, 大学院教授 2017: 日本医科大学, 医学(系)研究科(研究院), 教授 2015: 日本医科大学, 大学院医学研究科, 教授 2012 – 2015: 日本医科大学, 医学(系)研究科(研究院), 教授 2007 – 2010: Nippon Medical School, Graduate School of Medicine, Professor … More 2005 – 2006: Nippon Medical School, Graduate School of Medicine, Professor, 大学院医学研究科, 教授 2005: 日本医科大学, 大学院・医学研究科, 教授 1997 – 2004: 日本医科大学, 医学部, 助教授 1994 – 1996: 日本医科大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Anesthesiology Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / Basic Section 55060:Emergency medicine-related / Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator 遺伝子発現 / 一酸化窒素 / 日内変動 / 麻酔 / carboxy hemoglobin / carbon monoxide / nitric oxide / ヘムオキシゲナーゼ / 一酸化炭素 / ショック … More / 全身麻酔薬 / microRNA / 日内変動遺伝子 / 麻酔薬 / 発達形成 / 全身性炎症反応 / micro RNA / 虚血再潅流 / 神経発達 / 全身炎症性反応 / 虚血再潅流障害 / circadian gene / gene expression / anesthesia / anesthetics / 肺 / 脳 / 麻酔法 / cardiac depression / surgical insult / inflammation / 外科浸襲 / 外科侵襲 / 炎症性反応 / Carboxy hemoglobin / hemeoxygenase / nitric pride synthase / shock / エンドトキシンショック / 循環動態 / 一酸化窒素合成酵素 / CARDIAC CONTRACTILITY / REPERFUION INJURY / SHOCK / ELECTRON SPIN RESONANCE / NITRIC OXIDE / スピントラップ / Hb-NO / 電子スピン共鳴 / 心収縮力 / 再潅流障害 / 電子スピン共鳴装置 / miRNA / マイクロＲＮＡ / 神経障害性疼痛 / マイクロRNA / 静脈麻酔薬 / 吸入麻酔薬 / TLDA / 全身麻酔 / 代謝物変動 / 蛋白変動 / Pressor Response / Electron spin resonance / L-canavanine / Nitric-Oxide Syuthase / Nitrosyl-Hemoglobin … More Except Principal Investigator 麻酔薬 / 臓器保護 / 癌 / microRNA / Pringle's maneuver / Corticotropin-releasing factor / サイトカイン / HAS2/HAS2-AS1/HMGA2 / 細胞モデル / 急性呼吸促迫症候群 / miRNA / ＨIF1α / mRNA / 静脈麻酔薬 / HIF-1α / 局所麻酔薬 / WNT1経路 / HIF1α / ACE2 / 癌細胞生理 / 腎機能障害 / 敗血症 / β遮断薬 / Anesthetics / 全身麻酔 / 腎障害 / 筋障害 / 麻酔 / RNA シーケンス / 薬理学 / マイクロアレイ / 脳神経疾患 / 核酸 / 神経科学 / ヒトiPS細胞 / 長鎖ノンコーディングRNA / 脊髄神経結紮 / 神経障害性疼痛 / 後根神経節 / 一次感覚神経 / Neat1 / H19 / セボフルラン / Per２ / SCN / 株細胞 / GABA受容体 / 概日リズム / phase-shift / sevoflurane / Per2 / 時計遺伝子 / Tissue Doppler imaging / Transesophageal echocardiography / Diastolic dysfunction / Myocardial dysfunction / Proinflammatory cytokine / Partial hepatectomy / Ischemia reperfusion injury / 心機能低下 / iNOS mRNA / Hem oxygenase-1 mRNA / 心機能抑制 / 肝切除術 / 組織ドップラー / 経食道心エコー / 心拡張機能障害 / 心機能障害 / 炎症性サイトカイン / 肝部分切除術 / 虚血再灌流障害 / pain threashold / Glucocorticoid / Knockout mouse / acute pain / Stress-induced analgesia / 疼痛國値 / 疼痛域値 / 副腎皮質ホルモン / ノックアウトマウス / 急性疼痛 / ストレス性鎮痛作用 Less

The effect of Anesthetics via microRNA
- Principal Investigator
  
  Ishikawa Masashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nippon Medical School
The anesthetic effects on human cancer cell biology
- Principal Investigator
  
  Iwasaki Masae
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nippon Medical School
HAS2/HAS2-AS1/HMGA2 axis によるARDSの制御
- Principal Investigator
  
  杉田慎二
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Nippon Medical School
The effects of general anesthesia via microRNA
- Principal Investigator
  
  Ishikawa Masashi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nippon Medical School
Development of curative treatment against neuropathic pain through comprehensive functional analysis of human long non-coding RNAs
- Principal Investigator
  
  SUZUKI Hidenori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Nippon Medical School
Molecular biological study on action mechanism of general anestheticsPrincipal Investigator
- Principal Investigator
  
  Sakamoto Atsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Nippon Medical School
Characterization of sevoflurane effects on Per2 expression using ex vivo bioluminescence imaging of the suprachiasmatic in transgenic rats
- Principal Investigator
  
  Anzai Megumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Nippon Medical School
Mechanism elucidation of the general anesthesia from a view point of the changes in the internal gene expressionPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
Integrated examination of the effects of general anesthetics on genomics, proteomics and metabolomicsPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
The effects of anesthesia on internal gene expressionPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
The relation between the elevation of inflammatory mediators release and myocardial dysfunction after ischemia-reperfusion following Pringle's maneuver
- Principal Investigator
  
  NAKANISHI Kazuhiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
The roles of gaseous mediators during inflammatory cytokine induced cardiac depressionPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
Analysis of analgesic effect of CRF using Knockout mice
- Principal Investigator
  
  IMAKI Toshihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
RELATIONSHIP BETWEEN NITRIC OXIDE AND CARBONMONOXIDE DURING SHOCK AND ITS CONTROLPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  NIPPON MEDICAL SCHOOL
CHANGES IN NITRIC OXIDE PRODUCTION DURING SHOCK STATE AND ISCHEMIA-REPERFUSION INJURYPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Atsuhiro
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  NIPPON MEDICAL SCHOOL
内蔵虚血再潅流時の血中および組織一酸化窒素の変動と臓器血流におよぼす影響Principal Investigator
- Principal Investigator
  
  坂本篤裕
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School
心臓虚血再潅流時の一酸化窒素およびフリーラジカルの変動と心機能におよぼす影響Principal Investigator
- Principal Investigator
  
  坂本篤裕
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nippon Medical School

All 2023 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006

All Journal Article Presentation

[Journal Article] Dexmedetomidine Might Exacerbate Acute Kidney Injury, While Midazolam Might Have a Postconditioning Effect: A Rat Model of Lipopolysaccharide-Induced Acute Kidney Injury2023
- Author(s)
  Hata Akiko、Yamamoto Makiko、Iwasaki Masae、Morita Tomonori、Ishikawa Masashi、Sakamoto Atsuhiro
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 90 Issue: 5 Pages: 387-397
- DOI
  10.1272/jnms.JNMS.2023_90-406
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2023-10-25
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08934
[Journal Article] Specific microRNAs are involved in the reno-protective effects of sevoflurane preconditioning and ischemic preconditioning against ischemia reperfusion injury in rats.2020
- Author(s)
  Yamamoto M, Morita T, Ishikawa M, Sakamoto A.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 45 Pages: 1141-1149
- DOI
  10.3892/ijmm.2020.4477
- Data Source
  KAKENHI-PROJECT-18K08870
[Journal Article] Increased H19 Long Non-coding RNA Expression in Schwann Cells in Peripheral Neuropathic Pain2019
- Author(s)
  Iwasaki H, Sakai A, Maruyama M, Ito T, Sakamoto A, Suzuki H.
- Journal Title
  
  Journal of Nippon Medical School
  
  Volume: 86 Issue: 4 Pages: 215-221
- DOI
  10.1272/jnms.JNMS.2018_86-402
- NAID
  130007701659
- ISSN
  1345-4676, 1347-3409
- Year and Date
  2019-07-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05461
[Journal Article] miR-15b mediates oxaliplatin-induced chronic neuropathic pain through BACE1 down-regulation.2017
- Author(s)
  Ito N, Sakai A, Miyake N, Maruyama M, Iwasaki H, Miyake K, Okada T, Sakamoto A, Suzuki H.
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 5 Pages: 386-395
- DOI
  10.1111/bph.13698
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05461, KAKENHI-PROJECT-26861253, KAKENHI-PROJECT-16K10986, KAKENHI-PROJECT-16K15340, KAKENHI-PROJECT-15K10525, KAKENHI-PROJECT-26461596
[Journal Article] miR-15b mediates oxaliplatin-induced chronic neuropathic pain through BACE1 down-regulation.2017
- Author(s)
  to N, Sakai A, Miyake N, Maruyama M, Iwasaki H, Miyake K, Okada T, Sakamoto A, Suzuki H.
- Journal Title
  
  Br J Pharmacol.
  
  Volume: 174 Pages: 386-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10525
[Journal Article] Volatile anaesthetics enhance the metastasis related cellular signalling including CXCR2 of ovarian cancer cells.2016
- Author(s)
  Iwasaki M, Zhao H, Jaffer T, Unwith S, Benzonana L, Lian Q, Sakamoto A, Ma D
- Journal Title
  
  Oncotarget
  
  Volume: 7 Pages: 26042-26056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10525
[Journal Article] Establishment of an in vitro cell line experimental system for the study of inhalational anesthetic mechanisms.2016
- Author(s)
  Nagamoto S, Iijima N, Ishii H, Takumi K, Higo S, Aikawa S, Anzai M, Matsuo I, Nakagawa S, Takashima N, Shigeyoshi Y, Sakamoto A, Ozawa H.
- Journal Title
  
  Neuroscience Reseach.
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861252
[Journal Article] Characterization of sevoflurane effects on Per2 expression using exvivo bioluminescence imaging of the suprachiasmatic nucleus in transgenic rats2016
- Author(s)
  Matsuo I.,Iijima N.,Takumi K.,Higo S.,Aikawa S.,Anzai M., Ishii H., Sakamoto A.,Ozawa H
- Journal Title
  
  Neuroscience Research
  
  Volume: in press Pages: 30-37
- DOI
  10.1016/j.neures.2015.11.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460323, KAKENHI-PROJECT-15K20062, KAKENHI-PROJECT-25460319, KAKENHI-PROJECT-26670115, KAKENHI-PROJECT-15K10525
[Journal Article] Establishment of an in vitro cell line experimental system for the studablishment of an in vitro cell line experimental system for the study oy of inhalational anesthetic mechanisms.2016
- Author(s)
  Nagamoto S, Iijima N, Ishii H, Takumi K, Higo S, Aikawa S, Anzai M, Matsuo I, Nakagawa S, Takashima N, Shigeyoshi Y, Sakamoto A, Ozawa H.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 4;620: Pages: 163-168
- DOI
  10.1016/j.neulet.2016.04.005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460326, KAKENHI-PROJECT-25460319, KAKENHI-PROJECT-26670115, KAKENHI-PROJECT-26460323, KAKENHI-PROJECT-15K10525, KAKENHI-PROJECT-15K20062
[Journal Article] <b>Influence of neonatal sevoflurane exposure on nerve development-related microRNAs and behavior of </b><b>rats </b>2015
- Author(s)
  Fujimoto Y, Ishikawa M, Nagano M, Sakamoto A
- Journal Title
  
  Biomed. Res.
  
  Volume: 36 Issue: 6 Pages: 347-355
- DOI
  10.2220/biomedres.36.347
- NAID
  130005116839
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10525, KAKENHI-PROJECT-26461554, KAKENHI-PROJECT-25460345
[Journal Article] Identical microRNAs regulate liver protection during anesthetic and ischemic preconditioning in rats: animal study2015
- Author(s)
  Morita T, Ishikawa M, Sakamoto A
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: e0125866-e0125866
- DOI
  10.1371/journal.pone.0125866
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10525
[Journal Article] Volatile anesthetic sevoflurane ameliorates endotoxin-induced acute lung injury via microRNA modulation in rats2015
- Author(s)
  Otsuki T, Ishikawa M, Hori Y, Goto G, Sakamoto A
- Journal Title
  
  Biomedical Reports
  
  Volume: 3 Pages: 408-412
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10525
[Journal Article] Effect of electroconvulsive stimulation on messenger RNA expression in the prefrontal cortes in a rat pain model2015
- Author(s)
  Kimura Y, Ishikawa M, Hori Y, Okabe T, Sakamoto A
- Journal Title
  
  Biomedical Reports
  
  Volume: 3 Pages: 802-806
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10525
[Journal Article] Characterization of sevoflurane effects on Per2 expression using ex vivo bioluminescence imaging of the suprachiasmatic nucleus in transgenic rats.2015
- Author(s)
  Matsuo I, Iijima N, Takumi K, Higo S, Aikawa S, Anzai M, Ishii H, Sakamoto A, Ozawa H.
- Journal Title
  
  Neuroscience Reseach.
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26861252
[Journal Article] Changes in the gene expression levels of microRNAs in the rat hippocampus by sevoflurane and propofol anesthesia2014
- Author(s)
  Goto G, Hori Y, Ishikawa M, Tanaka S, Sakamoto A
- Journal Title
  
  MolMed Rep
  
  Volume: 9 Issue: 5 Pages: 1715-1722
- DOI
  10.3892/mmr.2014.2038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318
[Journal Article] Sevoflurane anesthesia persistently downregulates muscle-specific microRNAs in rat plasma2014
- Author(s)
  Jumpai Takeuchi, Atsuhiro Sakamoto, Toshihiro Takizawa
- Journal Title
  
  Int J Mol Med
  
  Volume: 34 Issue: 1 Pages: 291-298
- DOI
  10.3892/ijmm.2014.1739
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390383, KAKENHI-PROJECT-24592318
[Journal Article] Epigenetic supresiion of mouse Per2 expression in the suprachiasmatic nucleus by the inhalation anesthetic, sevoflurane2014
- Author(s)
  Mori K, Iijima N, Higo S, Aikawa S, Matsuo I, Takumi K, Sakamoto A, Ozawa H
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 1 Pages: e87319-e87319
- DOI
  10.1371/journal.pone.0087319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318, KAKENHI-PROJECT-24790241
[Journal Article] Differential expression of rat hippocampal micro RNA in two rat models of choronic pain2013
- Author(s)
  Hori Y, Goto G, Arai-Iwasaki M, Ishikawa M, Sakamoto A
- Journal Title
  
  Int J Mol Med
  
  Volume: 32 Issue: 6 Pages: 1287-1292
- DOI
  10.3892/ijmm.2013.1504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318
[Journal Article] microRNA changes in the dorsal horn of the spinal cord of rats with chronic constriction injury: A TqMan low density array study.2013
- Author(s)
  Genda Y, Arai M, Ishikawa M, Tanaka S, Okabe T, Sakamoto A
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 31 Issue: 1 Pages: 129-137
- DOI
  10.3892/ijmm.2012.1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318
[Journal Article] Changes in microRNA expression in rat lungs caused by sevoflurane anesthesia : a TaqMan low-density array study2012
- Author(s)
  Tanaka S, Ishikawa M, Arai M, Genda Y, Sakamoto A
- Journal Title
  
  Biomedical Research
  
  Volume: 33 Pages: 256-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318
[Journal Article] Differences in microRNA changes of healthy rat liver between sevoflurane and propofol anesthesia.2012
- Author(s)
  Ishikawa M, Tanaka S, Arai M, Genda Y, Sakamoto A
- Journal Title
  
  Anesthesiology
  
  Volume: 117 Issue: 6 Pages: 1245-1252
- DOI
  10.1097/aln.0b013e3182746676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592318
[Journal Article] The gereral anesthetic sevoflurane affects the expression of clock gene mPer2 accompanying the change of NAD(+) level in the suprachiasmatic nucleus of mice.2011
- Author(s)
  Ohe Y, Iijima N, Kadota K, Sakamoto A, Ozawa H
- Journal Title
  
  Neuroscience Letters 490
  
  Pages: 231-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] The general anesthetic sevoflurane effects the expression of clock gene mPer2 accompanying the change of NAD(+) level in the suprachiasmatic nucleus of mice.2011
- Author(s)
  Ohe Y, Sakamoto A, et al.
- Journal Title
  
  Neuroscience Letter
  
  Volume: 490 Pages: 231-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] Propofol anaesthesia alters the cerebral proteome differently from sevoflurane anaesthesia.2011
- Author(s)
  Tsuboko Y, Sakamoto A
- Journal Title
  
  Biomedical Research 32
  
  Pages: 55-65
- NAID
  130004903817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] Propofol anaesthesia alters the cerebral proteome differently from sevoflurane anaesthesia.2011
- Author(s)
  Tsuboko Y, Sakamoto A
- Journal Title
  
  Biomedical Research
  
  Volume: 32 Pages: 55-65
- NAID
  130004903817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] Pattern recognition analysis of proton nuclear magnetic resonance spectra of brain tissue extracts from rats anesthetized with propofol or sevoflurane.2010
- Author(s)
  Kawaguchi H, Sakamoto A, et al.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] Pattern recognition analysis of proton nuclear magnetic resonance spectra of brain tissue extracts from rats anesthetized with propofol or isoflurane.2010
- Author(s)
  Kawaguchi H, Hirakawa K, Miyauchi K, Koike K, Ohno Y, Sakamoto A
- Journal Title
  
  PLoS One. 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] The reciprocal relationship between heme oxygenase and nitric oxide syanthase in the organs of lipopolysaccharide-treated rodents.2009
- Author(s)
  Furuichi M., Sakamoto A., et al.
- Journal Title
  
  Biomedical Research 30
  
  Pages: 235-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] The influences of propofol and dexmedetomidine on cirdadian gene expression in rat brain.2009
- Author(s)
  Yoshida Y., Sakamoto A., et al.
- Journal Title
  
  Brain Research Bulletin 79
  
  Pages: 441-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] The influences of propofol and dexmedetomidine on cirdadian gene expression in rat brain.2009
- Author(s)
  Yoshida Y, Nakazato K, Takemori K, Kobayashi K, Sakamoto A
- Journal Title
  
  Brain Research Bulletin 79
  
  Pages: 441-444
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] Expressions of genes encoding drug-metabolizing enzymes are altered after sevoflurane, isoflurane, propofol or dexmedetomidine anesthesia.2009
- Author(s)
  Nakazato K, Yoshida Y, Takemori K, Kobayashi K, Sakamoto A
- Journal Title
  
  Biomedical Research 30
  
  Pages: 17-24
- NAID
  130004903744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] A transient inflammatory reaction in the lung after experimental hemorrhageic shock and resuscitation with a hemoglobin-vesicles solution compared with RBC transfusion.2009
- Author(s)
  Yamanashi Y., Sakamoto A., et al.
- Journal Title
  
  ASAIO Journal 55
  
  Pages: 478-483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591820
[Journal Article] The Prolonged Analgesic Effect of Epidural Ropivacaine in a Rat Model of Neuropathic Pain2008
- Author(s)
  Sato C., Sakai A., Ikeda Y., Suzuki H., Sakamoto A.
- Journal Title
  
  Anesthesia &Analgesia 106
  
  Pages: 313-320
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Expression of pulmonary vasoactive factors after sevoflurane anaesthesia in rats: a quantitative real-time polymerase chain reaction study.2008
- Author(s)
  Takemori K., Kobayashi K., Sakamoto, A.
- Journal Title
  
  British Journal of Anaesthesia 100
  
  Pages: 190-194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Expression of pulmonary vasoactive factors after sevoflurane anaesthesia in rats : a quantitative real-time polymerase chain reaction study.2008
- Author(s)
  Takemori, K., Kobayashi, K., Sakamoto, A
- Journal Title
  
  British Journal of Anaesthesia 100(2)
  
  Pages: 190-194
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] The Prolonged Analgesic Effect of Epidural Ropivacaine in a Rat Model of Neuropathic Pain2008
- Author(s)
  Sato, C., Saakai, A., Ikeda, Y., Suzuki, H., Sakamoto, A
- Journal Title
  
  Anesthesia & Analgesia 106(1)
  
  Pages: 313-320
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] The Prolonged Analgesic Effect of Epidural Ropivacaine in a Rat Model of Neuropathic Pain.2008
- Author(s)
  Sato C., Sakai A., Ikeda Y., Suzuki H., Sakamoto A.
- Journal Title
  
  Anesthesia & Analgesia 106
  
  Pages: 313-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Expression of pulmonary vasoactive factors after sevoflurane anaesthesia inrats:aquantitative real-time polymerase chain reaction study2008
- Author(s)
  Takemori K., Kobayashi K., Sakamoto, A.
- Journal Title
  
  British Journal of Anaesthesia 100
  
  Pages: 190-194
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Circadian gene expression is suppressed during sevoflurane anesthesia and the suppression persists after awakening.2007
- Author(s)
  Kobayashi, K., Takemori, K., Sakamoto, A.
- Journal Title
  
  Brain Research 1185
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Circadian gene expression is suppressed during sevoflurane anesthesia and the suppression persists after awakening.2007
- Author(s)
  Kobayshi K., Takemori K., Sakamoto A.
- Journal Title
  
  Brain Research 1185
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Circadian gene expression is suppressed during sevoflurane anesthesia and the suppression persists after awakening2007
- Author(s)
  Kobayshi K., Takemori K., Sakamoto A.
- Journal Title
  
  British Journal of Anaesthesia 1185
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591728
[Journal Article] Fluid resuscitation with hemoglobin vesicles in a rabbit model of acute hemorrhagic shock2006
- Author(s)
  Terajima, K., Tsueshita, T., Sakamoto, A., Ogawa, R
- Journal Title
  
  Shock 25(2)
  
  Pages: 184-189
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Presentation] 一次感覚神経節miR-15bのオキサリプラチン誘発性神経障害疼痛における解析2016
- Author(s)
  黒木直美，坂本篤裕
- Organizer
  第６３回日本麻酔学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] 一次感覚神経節miR-15bのオキサリプラチン誘発性神経障害性疼痛における解析2016
- Author(s)
  黒木直美、坂井敦、三宅紀子、三宅弘一、岡田尚巳、鈴木秀典、坂本篤裕
- Organizer
  第63回日本麻酔科学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-16H05461
[Presentation] miR-15b role in the oxaliplatin-induced neuropathic pain.2016
- Author(s)
  Sakai A, Ito-Kuroki N, Maruyama M, Miyake N, Iwasaki H, Miyake K, Okada T, Sakamoto A, Suzuki H.
- Organizer
  16th World Congress on Pain
- Place of Presentation
  Pacifico Convention Center
- Year and Date
  2016-09-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05461
[Presentation] 吸入麻酔薬作用機構の研究のためのcell lineを用いたin vivtro実験系の確立2016
- Author(s)
  永本盛嗣，坂本篤裕
- Organizer
  第６３回日本麻酔学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2016-05-26
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] オキサリプラチン誘発性神経障害性疼痛における後根神経節でのマイクロRNAの発現変化2015
- Author(s)
  伊藤直美、坂井敦、鈴木秀典、坂本篤裕
- Organizer
  第62回日本麻酔科学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] 肝臓虚血再灌流モデルにおけるセボフルランプレコンディショニングと虚血プレコンディショニングのmicroRNA発現変化の比較2015
- Author(s)
  森田智教、石川真士、坂本篤裕
- Organizer
  第62回日本麻酔科学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] Influence of neonatal sevoflurane exposure on nerve development-related microRNAs and behavior of rats2015
- Author(s)
  Fujimoto S, Nagano M, Ishikawa M, Sakamoto A
- Organizer
  American Society of Anesthesiologists. Annual meeting 2015
- Place of Presentation
  San Diego, California, USA
- Year and Date
  2015-10-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] ラット幼若期セボフルラン暴露が発達段階の海馬microRNA発現変化へ及ぼす影響2015
- Author(s)
  藤本彩子、永野昌俊、石川真士、坂本篤裕
- Organizer
  第62回日本麻酔科学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] 神経因性障害モデルラットに対するElectroconvulsive stimulationによる前頭野のmessengerRNA変化の検討2015
- Author(s)
  木村祐輔、保利陽子、石川真士、坂本篤裕
- Organizer
  第62回日本麻酔科学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15K10525
[Presentation] Changes of messenger RNA expression in the prerontal cortex of pain model rats by electroconvulsive stimulation2014
- Author(s)
  Yusuke Kimura, Atsuhiro Sakamoto
- Organizer
  2014 Annual meeting of American Society of Anesthesiologists
- Place of Presentation
  San Francisco (America)
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Common microRNAs regulate liver protection of anesthetic and ischemic preconditioning2014
- Author(s)
  Tomonori Morita, Masashi Ishikawa, Atsuhiro Sakamoto
- Organizer
  2014 Annual meeting of American Society of Anesthesiologists
- Place of Presentation
  San Francisco (America)
- Year and Date
  2014-10-13
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] ラット急性肺障害モデルにおける麻酔薬の作用とmicroRNAの発現変化2014
- Author(s)
  大槻達郎、石川真士、田中俊輔、保利陽子、後藤玄太郎、坂本篤裕
- Organizer
  日本麻酔科学会第61回学術集会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2014-05-15
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Changes in blood volume and colloid osmotic pressure during fluid absorption in patients undergoing endoscopic urosurgery2013
- Author(s)
  Yagi K, Kinugawa C, Sakamoto A
- Organizer
  The ANESTHESIOLOGY 2013 annual meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Epigenetic regulation of period expression in the mouse suprachiasmatic nucleus by sevoflurane2013
- Author(s)
  Mori K, Matsuo I, Higo S, Aikawa S, Anzai M, Iijima N, Ozawa H, Sakamoto A
- Organizer
  The ANESTHESIOLOGY 2013 annual meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Sevoflurane ameliorates lipopolysaccharide-induced acute lung injury and changes microRNA expression2013
- Author(s)
  Otsuki T, Ishikawa M, Tnaka S, Hori Y, Goto G, Sakamoto A
- Organizer
  The ANESTHESIOLOGY 2013 annual meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Sevoflurane anesthesia downregulates circulation muscle-derived miRNA2013
- Author(s)
  Takeuchi J, Takizawa T, Sakamoto A
- Organizer
  The ANESTHESIOLOGY 2013 annual meeting
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] ラット肝臓microRNA発現に対するセボフルラン、プロポフォールの影響2012
- Author(s)
  石川真士、田中俊輔、荒井雅江、源田雄紀、坂本篤裕
- Organizer
  第59回日本麻酔科学会学術集会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Chronic constriction injury rat脊髄後角のmicroRNA変化の検討ーTaqMan Loe Density Arrayを用いたmicroRNA網羅解析ー2012
- Author(s)
  源田雄紀、荒井雅江、石川真士、田中俊輔、岡部格、坂本篤裕
- Organizer
  第59回日本麻酔科学会学術集会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] Differential expression of hippocampal micromas in rat chronic pain models2012
- Author(s)
  Hori Y, Arai M, Ishikawa M, Genda Y, Tanaka S, Sakamoto A
- Organizer
  Annual Meeting of American Society of Anesthesiologists 2012
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-24592318
[Presentation] The general anesthetic sevoflurane effects the expression of clock gene mPer2 accompanying the change of NAD(+) level in the suprachiasmatic nucleus of mice.2010
- Author(s)
  Ohe H, Sakamoto A, et al.
- Organizer
  American Society of Anesthesiologists 2010 Annual Meeting
- Place of Presentation
  San Diego, California
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] The general anesthetic sevoflurane effects the expression of clock gene mPer2 accompanying the change of NAD(+) level in the suprachiasmatic nucleus of mice2010
- Author(s)
  Ohe Y, Sakamoto A, et al.
- Organizer
  American Society of Anesthesiologists 2010Annual Meeting
- Place of Presentation
  SanDiego、USA
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] 全身麻酔薬sevofluraneは時計遺伝子mPer2の発現をNAD上昇を伴い抑制する2010
- Author(s)
  大江裕美子、坂本篤裕, 他
- Organizer
  日本麻酔科学会第57回学術大会
- Place of Presentation
  福岡
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] The general anesthetic sevoflurane effects the expression of clock gene mPer2 accompanying the change of NAD(+)level in the suprachiasmatic nucleus of mice.2010
- Author(s)
  Ohe Y, Sakamoto A, et al.
- Organizer
  The 7th International Congress of Neuroendocrinology
- Place of Presentation
  Rouen, France
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] プロポフォール麻酔による脳プロテオームへの影響2009
- Author(s)
  坪光晃、坂本篤裕, 他
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸
- Year and Date
  2009-08-16
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] 全身麻酔薬sevofluraneは時計遺伝子mPer2の発現をNAD上昇を伴い抑制する2009
- Author(s)
  大江裕美子、坂本篤裕、他
- Organizer
  日本麻酔科学会第57回学術集会
- Place of Presentation
  福岡
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] セボフルラン、イソフルラン麻酔後のラット肝臓における薬物代謝系遺伝子発現への影響2008
- Author(s)
  中里桂子、坂本篤裕、他
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  横浜
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] Propofolによる脳プロテオームへの影響2008
- Author(s)
  坪光祥晃、坂本篤裕、他
- Organizer
  日本麻酔科学会第56回学術集会
- Place of Presentation
  神戸
- Year and Date
  2008-08-16
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] Propofolとdexmedetomidineによる脳内circadian geneの発現2008
- Author(s)
  吉田結富子、坂本篤裕、他
- Organizer
  日本麻酔科学会第55回学術集会
- Place of Presentation
  横浜
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20591820
[Presentation] セボフルレンは麻酔中サーカディアン遺伝子の発現を抑制し、そして覚醒後も抑制し続ける2007
- Author(s)
  小林克也、竹森健、坂本篤裕
- Organizer
  (社)日本麻酔科学会第54回学術集会
- Place of Presentation
  札幌
- Year and Date
  2007-05-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Presentation] The effect of hemoalibin-vesicles on resuscitation and inflammatory responses2007
- Author(s)
  Terajima, K., Tsueshita, T., Sakamoto, A
- Organizer
  54h annual meeting of Japanese Society of Anesthesiologists
- Place of Presentation
  Sapporo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Presentation] Sevoflurane suppressed expression of circadian genes and the effect persists long after awakening.2007
- Author(s)
  Kobayashi, K., Takemori, K., Sakamoto, A
- Organizer
  54h annual meeting of Japanese Society of Anesthesiologists
- Place of Presentation
  Sapporo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Presentation] Sevoflurane influenced ET-1 gene expression in the rat lung2007
- Author(s)
  Takemori, K., Kobayashi, K., Sakamoto, A
- Organizer
  54h annual meeting of Japanese Society of Anesthesiologists
- Place of Presentation
  Sapporo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728
[Presentation] The effect of propofol LCT on apoptosis of human neutrophils.2007
- Author(s)
  Kishikawa, H., Sakamoto, A., Andoh, T., Kawaguchi, H., Tsubokoh, S
- Organizer
  54h annual meeting of Japanese Society of Anesthesiologists
- Place of Presentation
  Sapporo, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591728

1. Ishikawa Masashi (30714745)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. Iwasaki Masae (20744428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. IMAKI Toshihiro (50183190)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYATA Mariko (70281631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKANISHI Kazuhiro (30217765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Anzai Megumi (30719000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. IIJIMA Norio (00285248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. OZAWA Hitoshi (60169290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. HIGO Shinpei (50623922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. TAKUMI Ken (40553269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. SUZUKI Hidenori (30221328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. 齋藤文仁 (20360175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 坂井敦 (30386156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 丸山基世 (60709757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 間瀬大司 (60614831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 杉田慎二 (60714756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 森田智教

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 大槻達郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 木村祐輔

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 藤本彩子

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 松尾いずみ

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 永本盛嗣

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 伊藤直美

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
24. ISHII Hirotaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 瀧澤俊広

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 重吉康史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAMOTO Atsuhiro 坂本 篤裕

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Molecular biological study on action mechanism of general anestheticsPrincipal Investigator

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Mechanism elucidation of the general anesthesia from a view point of the changes in the internal gene expressionPrincipal Investigator

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Integrated examination of the effects of general anesthetics on genomics, proteomics and metabolomicsPrincipal Investigator

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The effects of anesthesia on internal gene expressionPrincipal Investigator

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The roles of gaseous mediators during inflammatory cytokine induced cardiac depressionPrincipal Investigator

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RELATIONSHIP BETWEEN NITRIC OXIDE AND CARBONMONOXIDE DURING SHOCK AND ITS CONTROLPrincipal Investigator

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SAKAMOTO Atsuhiro 坂本篤裕