OTANI Kiyoshi 大谷清

… Alternative Names

Ohtani Kiyoshi 大谷清

OHTANI Kiyoshi 大谷清

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Researcher Number	30201974
Other IDs
External Links
Affiliation (Current)	2025: 関西学院大学, 生命環境学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 関西学院大学, 生命環境学部, 教授 2020: 関西学院大学, 理工学部, 教授 2009 – 2017: Kwansei Gakuin University, 理工学部, 教授 2007 – 2008: Tokyo Medical and Dental University, Human Gene Sciences Center, Lecturer 2005: 東京医科大学, 疾患遺伝子実験センター, 講師 … More 1997 – 2005: 東京医科歯科大学, 疾患遺伝子実験センター, 講師 1998: 東京医科歯科大, 疾患遺伝子実験センター, 助手 1991 – 1992: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Molecular biology / Basic Section 50010:Tumor biology-related / Virology / Biological Sciences Except Principal Investigator Biological Sciences / Immunology / Pathobiological dentistry/Dental radiology / Virology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Human genetics / Dental engineering/Regenerative dentistry / Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator E2F / p53 / ARF / RB / がん化抑制 / アポトーシス / pRB / TPA / Tax / gp34 … More / HTLV-I / NF-κB / 細胞増殖 / 転写 / p27Kip1 / 転写制御 / がん / 細胞周期 / DNA複製 / RelA / サイクリンD1 / WDR1 / DDX5 / CDK / 相互作用因子 / リン酸化 / がん抑制遺伝子 / T-cell / T細胞 / Bim / 発現制御 / 癌 / microRNA / PI3キナーゼ / 転写因子 / 細胞運命 / 癌化抑制 / DP / p27^<Kipl> / p14^<ARF> / 癌抑制遺伝子 / TP73 / 癌性変化 / p27KiP1 / 癌化 / Subtraction法 / Differential Display法 / サブトラクション / ディファレンシャルディスプレイ法 / サブトラクション法 / Jab1 / p27 / 標的遺伝子 / 哺乳動物細胞 / CDC6 / ORCl … More Except Principal Investigator 細胞周期 / Tax / HTLV-I / E2F / T細胞 / IL-2 / p53 / ウイルス / CDK / DRIL1 / リン酸化 / MMP / p51 / Smad / アポトーシス / 癌抑制遺伝子 / 発現制御 / 癌 / DNA合成 / MCM / がん微小環境 / HMG-CoA / メタボローム / 薬剤感受性 / HMGCR分解誘導剤 / ヒドロキシメチルグルタリルCoA / HMGCRタンパク分解誘導 / 制がん効果 / スタチン / HMGCR / スタチン感受性 / ドラッグリポジショニング / がん細胞 / スタチン系薬剤 / Cell Proliferation / Nuclear Matrix / Chromatin Remodeling / Tumor Suppressor Gene / Apontosis / Oral Cancer / E2FBP1 / DRIL 1 / 細胞増殖 / 核マトリクス / クロマチン構造変換 / 口腔癌 / CDK inhibitor / Cell cycle / T lymocytes / Rb / CDKインヒビター / Clamp-Clamp loader / Nuclear Matrix Attachment / Cyclin-dependent kinase / Cdc7 kinase / MCM complex / prereplicative complex / E2F transcription factor / G1-S transition / マウス胚性幹細胞 / MCM2 / Cdc7-ASKキナーゼ / ES細胞 / DNAヘリカーゼ / Cdcキナーゼ / DNA複製開始 / G1-S期移行 / クランプ=クランプローダー / 核マトリックス付着 / サイクリン依存性キナーゼ / Cdc7キナーゼ / MCMタンパク質 / DNA複製前複合体 / E2F転写因子 / G1-S期以降 / gene family / functional information / sequence information / 椎間板ヘルニア塊の消化 / マトリックス・メタロプロテアーゼ(MMP) / 間葉系細胞分化 / p51遺伝子 / p53関連遺伝子 / 遺伝子機能予測 / Furctional genomics / ファミリー遺伝子 / 近縁遺伝子群 / 機能情報 / 遺伝子情報 / T cell / DNA sythesis / cell cycle / HTLV-1 / high-affinity receptor / gamma chain / IL-2 receptor / 受容体サブユニット / ILー2受容体 / ILー2 / チロシンリン酸化 / γ鎖 / IL-2受容体 / 幹細胞 / 再生医学 / リプログラミング / 培養 / 線維芽細胞 / 再生医療 / 増殖因子 / 細胞培養 / 分化転換 / 間葉系幹細胞 / 繊維芽細胞 / 軟骨 / 骨 / 非破壊分析 / ラマン分光分析 / ラベルフリー検出 / リアルタイム検出 / ウイルス検出 / ラマン分光 / 核マトリクス結合因子 / 核内高次機能 / 分子生物学 / RB / 実験腫瘍学 / 転写促進 / プロモーター / テロメレース / 白血病 / トランスアクチベーション / ATL / E2F-1 / 蛋白質リン酸化 / ライセンシング因子 / S期導入因子 / 複製開始点結合因子 / PCNA / ORC / 染色体構造 / DNA修復 / クロマチン集合 / DNAメチル転移酵素 / S期 / PCNA結合タンパク質 / DNA複製 / NFーKB / 膜糖蛋白 / トランス活性化 / HAM / HTLVーI Less

Regulatory mechanism of deregulated E2F1 activity, which is crucial for tumor suppressionPrincipal Investigator
- Principal Investigator
  
  Ohtani Kiyoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kwansei Gakuin University
Classification based on oncometabolites of cancers for which statins are used and analysis of the effects of statins in tumor microenvironment
- Principal Investigator
  
  Warita Tomoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kwansei Gakuin University
Molecular mechanism of E2F regulation of cell proliferation and tumor suppressionPrincipal Investigator
- Principal Investigator
  
  Ohtani Kiyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kwansei Gakuin University
Trans-differentiation of human fibroblasts into chondrocytes and osteocytes and its application for regenerative medicine
- Principal Investigator
  
  IKEDA Masa-Aki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Tokyo Medical and Dental University
Development of optical detection and controlling method for virus infection
- Principal Investigator
  
  SATO Hidetoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kwansei Gakuin University
Molecular mechanism of tumor suppression mediated by the transcription factor E2FPrincipal Investigator
- Principal Investigator
  
  OHTANI Kiyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kwansei Gakuin University
Functional Roles of Nuclear Matrix Binding Factors in Major Tumor Suppressor Pathways in Human
- Principal Investigator
  
  IKEDA Masaaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical and Dental University
Cell fate decision mechanism by the transcription factor E2F in cell growth and tumor suppressionPrincipal Investigator
- Principal Investigator
  
  OHTANI Kiyoshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Kwansei Gakuin University
Analysis of E2F-mediated transcriptional mechanism, which specifically senses oncogenic changesPrincipal Investigator
- Principal Investigator
  
  OHTANI Kiyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Medical and Dental University
Regulation of Chromatin Remodeling and Transcription Involved in Tumor suppression and its Dysregulation in Oral Cancer
- Principal Investigator
  
  IKEDA Masa-aki
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Tokyo Medical and Dental University
HTLV-I Taxによる細胞周期促進
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HTLV-ITaxによる細胞周期促進の分子機構
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
G1期におけるDNA複製因子の発現と活性の制御機構の研究Principal Investigator
- Principal Investigator
  
  大谷清
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
HTLV-I Taxによる細胞周期転写因子E2F活性化の分子機構
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
From G1 regulators to Replication machinery
- Principal Investigator
  
  MASAI Hisao
- Project Period (FY)
  2000 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Molecular mechanism of cell cycle regulation in human T cells
- Principal Investigator
  
  NAKAMURA Masataka
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
Molecular basis on E2F acitivation by HTLV-I Tax
- Principal Investigator
  
  NAKAMURA Masataka
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
Molecular mechanisms of NF-κB mediated T-cell acitivation induced by HTLV-I TaxPrincipal Investigator
- Principal Investigator
  
  OHTANI Kiyoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
Identification of Gene Function from Sequence Information
- Principal Investigator
  
  YAMAMURA Yasuko, 井川洋二
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental University
HTLV-I Taxの細胞周期転写因子E2Fに及ぼす作用の解析
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tokyo Medical and Dental University
HTLV-I感染によるテロメレース活性化に関する研究
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University
HTLV-I Taxの細胞周期転写因子E2Fに及ぼす作用の解析
- Principal Investigator
  
  中村正孝
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
哺乳動物細胞のDNA複製開始機序の解析Principal Investigator
- Principal Investigator
  
  大谷清
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
p21によるPCNAの機能制御と細胞のがん化
- Principal Investigator
  
  TSURIMOTO Toshiki
- Project Period (FY)
  1996 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Nara Institute of Science and Technology
脳に特異的な膜抗原gp34とHTLVーI感染
- Principal Investigator
  
  NAKAMURA Masataka
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Tohoku University
Expression of interleukin 2 receptor subunits and mechanism of T cell growth
- Principal Investigator
  
  SUGAMURA Kazuo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  TOHOKU UNIVERSITY

[Book] Gene Expression and Regulation in Mammalian Cells - Transcription Toward the Establishment of Novel Therapeutics2018
- Author(s)
  Kenta Kurayoshi, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Hideyuki Komori, Keigo Araki and Kiyoshi Ohtani
- Total Pages
  27
- Publisher
  InTech Open Access Publisher
- ISBN
  9789535138686
- Data Source
  KAKENHI-PROJECT-15K06957
[Book] Future Aspects of Tumor Suppressor Gene2013
- Author(s)
  Ozono E, Yamaoka S and Ohtani K
- Publisher
  InTech Open Access Publisher
- Data Source
  KAKENHI-PROJECT-24570202
[Book] Therapeutic Targeting of p53-Mediated Apoptosis Pathway in Head and Neck Squamous Cell Carcinomas : Current Progress and Challenges, Tumor Suppressor Genes(Yue Cheng (Ed.))2012
- Author(s)
  Ichwan SJA, Bakhtiar MT, Ohtani K, Ikeda MA
- Total Pages
  16
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-21390502
[Book] Therapeutic Targeting of p53-mediated Apoptosis Pathway in Head and Neck Squamous Cell Carcinomas : Current Progress and Challenges. in "Tumor Suppressor Genes"2012
- Author(s)
  Ichwan, S., Bakhtiar, MT., Ohtani, K. and Ikeda, MA. Yue Cheng
- Total Pages
  16
- Publisher
  InTech Open Access Publisher
- Data Source
  KAKENHI-PROJECT-21570180
[Book] Therapeutic Targeting of p53-Mediated Apoptosis Pathway in Head and Neck Squamous Cell Carcinomas : CurrentProgress and Challenges Tumor Suppressor Genes, Yue Cheng(Ed.)2012
- Author(s)
  Ichwan SJA, Bakhtiar MT, Ohtani K, Ikeda MA
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-21390502
[Book] 染色体DNAの複製と安定性を司るRB/E2F-蛋白質・核酸・酵素2009
- Author(s)
  大谷清、大園瑛子
- Total Pages
  7
- Data Source
  KAKENHI-PROJECT-21570180
[Book] Yoshida, K. ed., Research Signpost2009
- Author(s)
  Ohtani, K., Komori, H., Ozono, E., Ikeda, M-A., Iwanaga R
- Publisher
  Distinct Transcriptional Regulation by E2F in Cell Growth and Tumor Suppression. in "Control of cellular physiology by the transcription factor E2F"
- Data Source
  KAKENHI-PROJECT-19570163
[Book] Distinct transcriptional regulation by E2F in cell growth and tumor suppression. in "Control of cellular physiology by the transcription factor E2F"2008
- Author(s)
  Ohtani, K., Komori, H., Ozono, E., Ikeda, M-A., Iwanaga R.
- Total Pages
  15
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-19570163
[Book] Gann Monograph on Cancer Research : Molecular mechanism of Tax-mediated cell growth of human T lymphocytes.2003
- Author(s)
  Ohtani, K. et al.
- Publisher
  The Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-12141201
[Journal Article] Deregulated E2F activity as a cancer-cell specific therapeutic tool2023
- Author(s)
  Rinka Nakajima, Lin Zhao, Yaxuan Zhou, Mashiro Shirasawa, Ayato Uchida, Hikaru Murakawa, Mariana Fikriyanti, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Tomoko Warita and Kiyoshi Ohtani
- Journal Title
  
  Genes
  
  Volume: 14 Issue: 2 Pages: 393-393
- DOI
  10.3390/genes14020393
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07136, KAKENHI-PROJECT-22K09946
[Journal Article] The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F2023
- Author(s)
  Nakajima R, Deguchi R, Komori H, Zhao L, Zhou Y, Shirasawa M, Angelina A, Goto Y, Tohjo F, Nakahashi K, Nakata K, Iwanaga R, Bradford AP, Araki K, Warita T, Ohtani K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 663 Pages: 154-162
- DOI
  10.1016/j.bbrc.2023.04.092
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09946, KAKENHI-PROJECT-21K07136
[Journal Article] Engineered Polymeric Nanovector for Intracellular Peptide Delivery in Antitumor Therapy2023
- Author(s)
  Zhang Xi、Zhang Mingming、Huang Sijun、Ohtani Kiyoshi、Xu Li、Guo Yi
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: Volume 18 Pages: 5343-5363
- DOI
  10.2147/ijn.s427536
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07136
[Journal Article] Expanding Roles of the E2F-RB-p53 Pathway in Tumor Suppression.2023
- Author(s)
  Zhou Y, Nakajima R, Shirasawa M, Fikriyanti M, Zhao L, Iwanaga R, Bradford AP, Kurayoshi K, Araki K, Ohtani K.
- Journal Title
  
  Biology (Basel)
  
  Volume: 12(12) Issue: 12 Pages: 1-49
- DOI
  10.3390/biology12121511
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09946, KAKENHI-PROJECT-21K07136
[Journal Article] The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity2017
- Author(s)
  Kenta Kurayoshi, Junko Okuno, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Kazuyuki Kugawa, Keigo Araki, Kiyoshi Ohtani
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 482(4) Issue: 4 Pages: 784-790
- DOI
  10.1016/j.bbrc.2016.11.111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06770, KAKENHI-PROJECT-15K06957
[Journal Article] Ectopic expression of the CDK inhibitor p21Cip1 enhances deregulated E2F activity and increases cancer cell-specific cytotoxic gene expression mediated by the ARF tumor suppressor promoter2017
- Author(s)
  Kenta Kurayoshi, Ayumi Shiromoto, Eiko Ozono, Ritsuko Iwanaga, Andrew P. Bradford, Keigo Araki, Kiyoshi Ohtani
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 483(1) Issue: 1 Pages: 107-114
- DOI
  10.1016/j.bbrc.2016.12.185
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06770, KAKENHI-PROJECT-15K06957
[Journal Article] The Interaction Mode of the Acidic Region of the Cell Cycle Transcription Factor DP1 with TFIIH2016
- Author(s)
  Masahiko Okuda, Keigo Araki, Kiyoshi Ohtani, Yoshifumi Nishimura
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 428(24) Issue: 24 Pages: 4993-5006
- DOI
  10.1016/j.jmb.2016.11.001
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06770, KAKENHI-PROJECT-15K06957
[Journal Article] Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts2015
- Author(s)
  Kitamura H, Ozono E, Iwanaga R, Bradford AP, Okuno J, Shimizu E, Kurayoshi K, Kugawa K, Toh H, Ohtani K.
- Journal Title
  
  Genes Cells
  
  Volume: 20 Pages: 739-757
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06957
[Journal Article] Noninvasive and label-free determination of virus infected cells by Raman spectroscopy.2014
- Author(s)
  Moor K, Ohtani K, Myrzakozha D, Zhanserkenova O, Andriana BB, Sato H
- Journal Title
  
  J Biomed Opt
  
  Volume: 19(6) Issue: 6 Pages: 67003-67003
- DOI
  10.1117/1.jbo.19.6.067003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24310015, KAKENHI-PROJECT-24570202, KAKENHI-PROJECT-25560211
[Journal Article] Cancer cell specific cytotoxic gene expression mediated by ARF tumor suppressor promoter constructs2014
- Author(s)
  Kurayoshi K, Ozono E, Iwanaga R, Bradford AP, Komori H, Ohtani K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 450 Issue: 1 Pages: 240-246
- DOI
  10.1016/j.bbrc.2014.05.102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570202
[Journal Article] Inability of p53-reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient in p53Ser46 phosphorylation2012
- Author(s)
  Ma, T., Yamada, S., Ichwan, S., Iseki, S., Ohtani, K., Otsu, M., Ikeda, MA.
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570180
[Journal Article] Inability of p53-Reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient for p53Ser46 phosphorylation2012
- Author(s)
  Ma, T, Yamada S, Ichwan SJA, Ohtani K, Iseki S, Otsu M, Ikeda MA
- Journal Title
  
  Biochem. Biophys. Res. Commun
  
  Volume: 417 Pages: 931-937
- Data Source
  KAKENHI-PROJECT-21390502
[Journal Article] Inability of p53-Reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient for p53Ser46 phosphorylation2012
- Author(s)
  Ma, T, Yamada S, Ichwan SJA, Ohtani K, Iseki S, Otsu M, Ikeda MA
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 417 Issue: 3 Pages: 931-937
- DOI
  10.1016/j.bbrc.2011.11.161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390502, KAKENHI-PROJECT-21590219, KAKENHI-PROJECT-21659454
[Journal Article] Tumor suppressor TAp73 gene specifically responds to deregulated E2F activity in human normal fibroblasts2012
- Author(s)
  Ozono E, Ohtani K.
- Journal Title
  
  Genes Cells
  
  Volume: 17 Pages: 660-672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24570202
[Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential2010
- Author(s)
  Ohno Y, Yasunaga S, Ohtsubo M, Mori S, Tsumura M, Okada S, Ohta T, Ohtani K, Kobayashi M, Takihara Y
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 21529-21534
- Data Source
  KAKENHI-PROJECT-21390502
[Journal Article] Hoxb4 transduction down-regulates Geminin protein, providing hematopoietic stem and progenitor cells with proliferation potential2010
- Author(s)
  Ohno, Y., Yasunaga, S., Ohtsubo, M., Mori, S., Tsumura, M., Okada, S., Ohta, T., Ohtani, K., Kobayashi, M., and Takihara, Y.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 107 Pages: 21529-21534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570180
[Journal Article] E2F-like elements in p27K'Pl promoter specifically sense deregulated E2F activity2009
- Author(s)
  Ozono, E., Komori, H., Iwanaga, R., Ikeda, MA., Iseki, S., Ohtani, K
- Journal Title
  
  Genes Cells 14
  
  Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] E2F-like elements in p27(Kip1) promoter specifically sense deregulated E2F activity2009
- Author(s)
  Ozono E, Komori H, Iwanaga R, Ikeda MA, Iseki S, Ohtani K
- Journal Title
  
  Genes Cells
  
  Volume: 14 Pages: 89-99
- Data Source
  KAKENHI-PROJECT-21390502
[Journal Article] E2F-like elements in p27^<kip1> promoter specifically sense deregulated E2F activity.2009
- Author(s)
  Ozono, E., Komori, H., Iwanaga, R., Ikeda, MA., Iseki, S., Ohtani, K.
- Journal Title
  
  Genes to Cells 14
  
  Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article]2009
- Author(s)
  大谷清(共著)
- Journal Title
  
  染色体サイクル(共立出版)
- Data Source
  KAKENHI-PROJECT-21570180
[Journal Article] 染色体DNA複製と安定性を司るRB/E2F2009
- Author(s)
  大谷清, 大園瑛子
- Journal Title
  
  蛋白質・核酸・酵素 54
  
  Pages: 327-333
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] E2F-like elements in p27(Kip1)promoter specifically sense deregulated E2F activity2009
- Author(s)
  Ozono E, Komori H, Iwanaga R, Ikeda MA, Iseki S, Ohtani K
- Journal Title
  
  Genes Cells 14
  
  Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390502
[Journal Article] E2F-like elements in p27Kip1 promoter specifically sense deregulated E2F activity2009
- Author(s)
  Ozono, E., Komori, H., Iwanaga, R., Ikeda, MA., Iseki, S., and Ohtani, K.
- Journal Title
  
  Genes Cells
  
  Volume: 14 Pages: 89-99
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21570180
[Journal Article] A role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase gene in human T cells2008
- Author(s)
  Hara, T., Matsumura-Arioka, Y., Ohtani, K., Nakamura, M
- Journal Title
  
  Cancer Science 29
  
  Pages: 1155-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] A role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase gene in human T cells2008
- Author(s)
  Hara T, Matsumura-Arioka Y, Ohtani K, Nakamura M.
- Journal Title
  
  Cancer Science (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] A role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase gene in human T cells.2008
- Author(s)
  Hara, T., Matsumura-Arioka, Y., Ohtani, K., Nakamura, M.
- Journal Title
  
  Cancer Science 99
  
  Pages: 1155-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] Activation of the cyclin D2 and cdk6 genes through NF-KB is critical for cell cycle progression induced by HTLV-I Tax2008
- Author(s)
  Iwanaga, R., Ozono, E., Fujisawa, J., Ikeda, MA., Okamura, N., Huang, Y., Ohtani, K
- Journal Title
  
  Oncogene 27
  
  Pages: 5635-5642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] A role of human T-cell leukemia virus type I Tax in expression of the human telomerase reverse transcriptase gene in human T cells2008
- Author(s)
  Hara T, Matsumura-Arioka Y, Ohtani K, Nakamura M
- Journal Title
  
  Cancer Science (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] A role of human T-cell leukemia virus type I Tax in expression of the human te lomerase reverse transcriptase gene in human T cells2008
- Author(s)
  Hara T, Matsumura-Arioka Y, Ohtani K, Nakamura M
- Journal Title
  
  Cancer Science (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Activation of the cyclin D2 and cdk6 genes through NF-kB is critical for cell cycle progression induced by HTLV-I Tax.2008
- Author(s)
  Iwanaga, R., Ozono, E., Fujisawa, J., Ikeda, MA., Okamura, N., Huang, Y., Ohtani, K.
- Journal Title
  
  Oncogene 27
  
  Pages: 5635-5642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] Activation of the cyclin D2 and cdk6 genes through NF-kB is critical for cell cycle progression induced by HTLV-I Tax2008
- Author(s)
  Iwanaga R, Ozono E, Fujisawa J, Ikeda MA, Okamura N, Huang Y, Ohtani K.
- Journal Title
  
  Oncogene (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Activation of the cyclin D2 and cdk6 genes through NF-kB is critical for cell cycle progression induced by HTLV-I Tax.2008
- Author(s)
  Iwanaga R, Ozono E, Fujisawa J, Ikeda MA, Okamura N, Huang Y, Ohtani K.
- Journal Title
  
  Oncogene (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] HTLV-1 Tax-induced NF K B activation is independent of Lys-63-linked-type polyubiquitination2007
- Author(s)
  Gohda, J., Irisawa, M., Tanaka, Y., Sato, S., Ohtani, K., Fujisawa, J., Inoue, J
- Journal Title
  
  Biochem Biophys Res Commun 357
  
  Pages: 225-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] HTLV-1 Tax-induced NF-kB activation is independent of Lys-63-linked-type polyubiquitination2007
- Author(s)
  Gohda J, Irisawa M, Tanaka Y, Sato S, Ohtani K, Fujisawa J, Inoue J
- Journal Title
  
  Biochem. Biophys. Res. Commun. 357
  
  Pages: 225-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] HTLV-1 Tax-induced NF-kB activation is independent of Lys-63-linked-type polyu biquitination2007
- Author(s)
  Gohda J, Irisawa M, Tanaka Y, Sato S, Ohtani K, Fujisawa J, Inoue J
- Journal Title
  
  Biochem. Biophys. Res. Commun. 357
  
  Pages: 225-230
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] HTLV-I Tax-induced NF-κB activation is independent of Lys-63-linked-type polyubiquitination.2007
- Author(s)
  Gohda J, Irisawa M, Tanaka Y, Sato S, Ohtani K, Fujisawa J and Inoue J
- Journal Title
  
  Biochem. Biophys. Res. Commun. 357
  
  Pages: 225-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570163
[Journal Article] HTLV-1 Tax-induced NF-κB activation is independent of Lys-63- -linked-type polyubiquitination2007
- Author(s)
  Gohda J, Irisawa M, Tanaka Y, Sato S, Ohtani K, Fujisawa J, Inoue J
- Journal Title
  
  Biochem. Biophys. Res. Comm 357
  
  Pages: 225-230
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity2006
- Author(s)
  Goto Y, Hayashi R, Muramatsu T, Ogawa H, Eguchi I, Oshida Y, Ohtani K, Yoshida K
- Journal Title
  
  Biochim Biophys Acta 1759
  
  Pages: 60-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Identification of novel E2F1 target genes regulated in cell cycle-dependent and independent manners2006
- Author(s)
  Iwanaga R, Komori H, Ishida S, Okamura N, Nakayama K, Nakayama K-I Ohtani K
- Journal Title
  
  Oncogene 25
  
  Pages: 1786-1798
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin2006
- Author(s)
  Masai H, Taniyama C, Ogino K, Matsui E, Kakusho N, Matsumoto S., Kim JM, Ishii A, Tanaka T, Kobayashi T, Tamai K, Ohtani K, Arai K
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 39249-39261
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin2006
- Author(s)
  Masai H, Taniyama C, Ogino K, Matsui E, Kakusho N, Matsumoto S., Kim JM. Ishii A, Tanaka T, Kobayashi T, Tamai K, Ohtani K, Arai K
- Journal Title
  
  J. Biol. Chem. 281
  
  Pages: 39249-39261
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] JPO1/CDCA7, a novel transcription factor E2F1-induced protein, possesses intrinsic transcriptional regulator activity2006
- Author(s)
  Goto Y, Hayashi R, Muramatsu T, Ogawa H, Eguchi I, Oshida Y, Ohtani K, Yoshida K
- Journal Title
  
  Biochim Biophys Acta. 1759
  
  Pages: 60-68
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Identification of two distinct elements mediating activation of telomerase (hTERT) gene expression in association with cell growth in human T cells2005
- Author(s)
  Matsumura-Arioka Y, Ohtani K, Hara T, Iwanaga R, Nakamura M
- Journal Title
  
  Int. Immunol. 17
  
  Pages: 207-215
- NAID
  10014376433
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Identification of two distinct elements mediating activation of telomerase(hTERT) gene expression in association with cell growth in human T cells2005
- Author(s)
  Matsumura-Arioka Y, Ohtani K, Hara T, Iwanaga R, Nakamura M.
- Journal Title
  
  Int. Immunol 17
  
  Pages: 207-215
- NAID
  10014376433
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Abstract Distinct E2F-mediated transcriptional program regulates p14ARF gene expression.2005
- Author(s)
  Komori, H., Enomoto, M., Nakamura, M., Iwanaga, R., Ohtani, K.
- Journal Title
  
  EMBO J. 24
  
  Pages: 3724-3736
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12141101
[Journal Article] Abstract Distinct E2F-mediated transcriptional program regulates p14ARF gene expression.2005
- Author(s)
  Komori, H., Enomoto M., Nakamura, M., Iwanaga, R, Ohtani, K.
- Journal Title
  
  EMBO J. 24
  
  Pages: 3724-36
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12141101
[Journal Article] Distinct E2F-Mediated transcriptional program regulates p14ARF gene expression2005
- Author(s)
  Komori H, Enomoto M, Nakamura M, Iwanaga R, Ohtani K
- Journal Title
  
  EMBO J. 24
  
  Pages: 3724-3736
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Distinct E2F-mediated transcriptional program regulates p14ARF gene expression2005
- Author(s)
  Komori H, Enomoto M, Nakamura M, Iwanaga R, Ohtani K
- Journal Title
  
  EMBO J. 24
  
  Pages: 3724-3736
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Differential regulation of expression of the mammalian DNA repair genes by growth stimulation2004
- Author(s)
  Iwanaga R, Komori H, Ohtani K
- Journal Title
  
  Oncogene 23
  
  Pages: 8581-8590
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] Differential regulation of expression of the mammalian DNA repair genes by growth stimulation2004
- Author(s)
  Iwanaga R, Komori H, Ohtani K.
- Journal Title
  
  Oncogene 23
  
  Pages: 8581-8590
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Journal Article] CDK2-dependent and-independent pathways in E2F-mediated S phase induction.2000
- Author(s)
  Arata, Y., Fujita, M., Ohtani, K., Kijima, S, Kato, J-Y.
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 6337-6345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12141101
[Journal Article] Cell type-specific E2F activation and cell cycle progression induced by the oncogene product Tax of human T-cell leukemia virus type I.2000
- Author(s)
  Ohtani, K. et al.
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 11154-11163
- Data Source
  KAKENHI-PROJECT-12141201
[Journal Article] CDK2-dependent and-independent pathways in E2F-mediated S phase induction.2000
- Author(s)
  Arata, Y., Fujita, M., Ohtani, K., Kijima, S., Kato, J-Y.
- Journal Title
  
  J.Biol.Chem. 275
  
  Pages: 6337-6345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12141101
[Patent] がん細胞標的ベクター、がん細胞特異的に目的遺伝子を発現させる方法及びがん細胞特異的に目的遺伝子を発現させるための使用2014
- Inventor(s)
  大谷　清
- Industrial Property Rights Holder
  学校法人関西学院
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-091857
- Filing Date
  2014-04-25
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] pRBの制御を外れたE2F1によるWDR1遺伝子の活性化は、E2F1によるがん化抑制機構に正のフィードバックを形成する2023
- Author(s)
  白澤真白、中島梨夏、周雅軒、大谷清
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] 上皮系細胞における転写因子E2Fによるがん抑制遺伝子の特異な制御機構2023
- Author(s)
  周雅軒、中島梨夏、白澤真白、大谷清
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] RelAは正常細胞においてRBの制御を外れたE2F1活性を抑制する2023
- Author(s)
  李岳琪、大谷清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] 正常細胞においてDDX5は、がん抑制遺伝子を活性化するE2F1活性を増強し、p53依存性の細胞死誘導に貢献する2023
- Author(s)
  中島梨夏、白澤真白、周雅軒、大谷清
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] RBの制御を外れたE2F1によるWDR1遺伝子の活性化は、E2F1によるがん化抑制機構に正のフィードバックを形成する2023
- Author(s)
  白澤真白、大谷清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] 転写因子E2Fのヘテロ二量体パートナーであるDP1をコードするTFDP1遺伝子は、制御の外れたE2Fの標的である2023
- Author(s)
  中島梨夏、大谷清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] 上皮系細胞における転写因子E2Fによるがん抑制遺伝子の特異な制御機構2023
- Author(s)
  周雅軒、大谷清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] サイクリンD1はE2F1の転写活性を抑制することで、E2F1の誘導するアポトーシスを抑制する2023
- Author(s)
  中島梨夏、大谷清
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] ヒト非小細胞肺がん細胞株においてRNAメチルトランスフェラーゼNSUN5をノックダウンするとがん抑制遺伝子のmRNAが安定化する2023
- Author(s)
  上田穂乃佳、大谷清
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] 正常細胞においてDEAD/H box 5（DDX5）はp53依存的にE2Fによるアポトーシス誘導を増強する2022
- Author(s)
  中島梨夏、大谷清
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] サイクリンD1は、過剰発現されたE2F1を細胞質に捕捉することにより、その活性を抑制する2022
- Author(s)
  中島梨夏、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] スタチン感受性の異なる肺がん細胞におけるメタボロームおよびトランスクリプトームプロファイリングの比較解析2022
- Author(s)
  割田友子、入江七海、周雅軒、田代二朗、杉浦曜大、溝口佳奈、大谷清、石川拓郎、割田克彦、Oltvai ZN.
- Organizer
  日本生理学会第100回記念大会
- Data Source
  KAKENHI-PROJECT-20K07666
[Presentation] WD Repeat Domain 1（WDR1）はRBの制御を外れたE2F1活性を増強する2022
- Author(s)
  村川ひかる、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] RelAは、がん細胞株においてRBの制御を外れたE2F活性を抑制している2022
- Author(s)
  川﨑友希、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] がん細胞の糖代謝活性レベルとスタチン感受性との関連2022
- Author(s)
  竹本昴平、割田友子、大谷清
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K07666
[Presentation] 上皮系細胞において、アポトーシス関連のがん抑制遺伝子は、RBの制御を外れたE2Fによって活性化されるが、増殖刺激により生理的に誘導されたE2Fによっては活性化されない2022
- Author(s)
  毛利勇登、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] がん抑制遺伝子ARFは、複数の非典型的なE2F反応性エレメントを介して、RBの制御を外れたE2F活性に応答する2022
- Author(s)
  内田彪斗、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] スタチンとHMG-CoA還元酵素分解誘導剤SR-12813との併用による制がん効果2022
- Author(s)
  周雅軒、大谷清、割田友子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07666
[Presentation] スタチンによる制がん効果の解析を目的とした最適な内部標準の探索2022
- Author(s)
  入江七海、大谷清、割田友子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K07666
[Presentation] RBの制御を外れたE2F活性を利用したがん細胞検出の試み2022
- Author(s)
  増田仁貴、割田友子、大谷清
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] サイクリンD1はRBの制御を外れたE2F1活性を抑制する2021
- Author(s)
  中島梨夏、割田友子、大谷清
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] Relationship between cholesterol synthesis in cancer cells and anticancer effect of statins.2021
- Author(s)
  T. Warita, K. Ohtani, T. Ishikawa, Z. N. Oltvai, K. Warita
- Organizer
  2021 World Conference on Lung Cancer of the International Association for the Study of Lung Cancer (WCLC 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07666
[Presentation] 転写因子 E2F1のN末端領域には新規転写活性化領域が存在し、基本転写因子GTF2H2と相互作用する2021
- Author(s)
  趙琳、割田友子、大谷清
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07136
[Presentation] アデノウイルスE1Aによる転写因子E2F3の新しい発現制御機構2017
- Author(s)
  服部拓, 荒木啓吾, 大谷清
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] 転写因子E2F1のN末端領域に対する新規相互作用因子WDR1の機能解析2017
- Author(s)
  根岸泰明, 荒木啓吾, 大谷清
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] がん抑制遺伝子発現制御における活性化型E2FのN末端領域の役割2017
- Author(s)
  尾田衡弥, 荒木啓吾, 大谷清
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] サイクリン依存性キナーゼによる制御を外れたE2F1活性抑制機構の解析2017
- Author(s)
  津田大輔, 荒木啓吾, 大谷清
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] p27Cip1 induces apoptosis specifically in cancer cells through up-regulation of the E2F activity2017
- Author(s)
  倉吉健太, 大谷清
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] 転写因子E2Fの新たなメンバーであるE2F3dはミトコンドリアに局在する2016
- Author(s)
  荒木啓吾、芳田亮輔、大谷清
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] DDX5 promotes ARF gene expression and apoptosis induced by deregulated E2F12016
- Author(s)
  Kurayoshi K and Ohtani K
- Organizer
  AACR Annual Meeting 2016
- Place of Presentation
  Ernest N. Morial Convention Center (New Orleans, USA)
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] がん細胞に特異的に存在する制御を外れたE2F活性は自殺遺伝子のがん細胞特異的発現に有用である2016
- Author(s)
  倉吉健太、大谷清
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] Critical role of ARID3B in the expression of E2F-responsive genes and cell proliferation2016
- Author(s)
  Saadat KASM，Pratama E, Lestari W，Ma T, Ohtani K，Ikeda MA
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26293419
[Presentation] Utility of an artificial promoter, ERE73s-ARF core, for driving suicide gene expression specifically in cancer cells2016
- Author(s)
  倉吉健太、大谷清
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] DDX5はpRBの制御を外れた転写因子E2F1の転写活性化能を増強する2015
- Author(s)
  芳田亮輔、西淵剛平、中山潤一、大谷清
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] PI3K経路はE2FによるBimとARF遺伝子の発現誘導を阻害しない2015
- Author(s)
  倉吉健太、大谷清
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場（愛知県・名古屋市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] ARID3B promotes gene expression critical for E2f-mediated cell cycle progression and p53-mediated apoptosis2015
- Author(s)
  Pratama E, Saadat KASM，Lestari W，Ichwan S, Iseki S, Ohtani K，Ikeda MA
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸国際会議場、兵庫県、神戸市
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26293419
[Presentation] Expression study of E2F-target genes in osteosarcoma (U2OS) and glioblastoma (T98G) cell lines after knocking down ARID3A and ARID3B2015
- Author(s)
  Saadat KASM, Kaifee A, Ahmet A, Iseki S, Ohtani K, Ikeda MA
- Organizer
  XIV. National Congress of Medical Biology and Genetics
- Place of Presentation
  Oludeniz-Fethiye, Turkey
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293419
[Presentation] ヒトT細胞白血病ウイルスの転写制御因子TaxによるCARM1遺伝子の発現誘導は、Taxによる標的遺伝子発現と細胞周期進行に貢献する2015
- Author(s)
  好川翔平、大谷清
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] Overexpression of ARID3 facilitates E2F-dependent apoptosis2015
- Author(s)
  Saadat KASM, Kaifee A, Ahmet A, Ohtani K, Ikeda MA
- Organizer
  XIV. National Congress of Medical Biology and Genetics
- Place of Presentation
  Oludeniz-Fethiye, Turkey
- Year and Date
  2015-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293419
[Presentation] PI3K経路は制御を外れたE2F1によるBimおよびARF遺伝子の発現誘導を抑制しない2015
- Author(s)
  倉吉健太、大谷清
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] 転写因子E2F1のARFプロモーター活性化能に関わるリン酸化部位の検索2015
- Author(s)
  脇田かおり、大谷清
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県・神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PROJECT-15K06957
[Presentation] Early Detection of Virus Infection by Raman Spectroscopy2013
- Author(s)
  K. Moor, K. Otani, B. B. Andriana and H. Sato
- Organizer
  ICAVS
- Place of Presentation
  神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25560211
[Presentation] Role of ARID3A and ARID3B in Cell Growth and E2F-target gene expression2012
- Author(s)
  Khandakar A S M Saadat, Endrawan Pratama, Kiyoshi Ohtani, Masa-Aki Ikeda
- Organizer
  2nd Heidelberg Forum for Young Life Scientists
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Inability of p53-Reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient for p53Ser46 phosphorylation2012
- Author(s)
  Teng Ma Shumpei Yamada, Solachuddin J. A. Ichwan, Sachiko Iseki, Kiyoshi Ohtani, Megumi Otsu, Masa-Aki Ikeda
- Organizer
  3rd Cancer Targets and Therapeutics
- Place of Presentation
  Las Vegas, Nevada, USA
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Inability of p53-Reactivating compounds Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient for p53Ser46 phosphorylation2012
- Author(s)
  Teng Ma Shumpei Yamada, Solachuddin J. A. Ichwan, Sachiko Iseki, Kiyoshi Ohtani, Megumi Otsu, Masa-Aki Ikeda
- Organizer
  2nd Heidelberg Forum for Young Life Scientists
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Inability of Nutlin-3 and RITA to overcome p53 resistance in tumor cells deficient for p53Ser46 phosphorylation2011
- Author(s)
  Teng Ma, Shumpei Yamada, Solachuddin J. A Ichiwan, Kiyoshi Ohtani, Megumi Ostu, Masa-Aki Ikeda
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Role of ARID3A and ARID3B in Cell Growth and E2F-Target Gene Expression2011
- Author(s)
  Khandakar A S M Saadat, Endrawan Pratama, Kiyoshi Ohtani, Masa-Aki Ikeda
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-16
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Effect of Nutlin-3 on p53 resistance in tumor cells lacking the ability to phosphorylate Ser46on p532010
- Author(s)
  Teng Ma, Shumpei Yamada, Ichwan Solachuddin J. A., Megumi Ostu, Kiyoshi Ohtani, Masa-Aki Ikeda
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Effect of Nutlin-3 on p53 resistance in tumor cells lacking the ability to phosphorylate Ser46 on p532010
- Author(s)
  Teng Ma, Shumpei Yamada, Ichwan Solachuddin J.A., Megumi Ostu, Kiyoshi Ohtani, Masa-Aki lkeda
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] Cell type-specific effect of HTLV-I Tax2009
- Author(s)
  Ohtani, K.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21570180
[Presentation] Effect of Nutlin-3 on p53 resistance in tumor cells lacking the ability to phosphorylate Ser46 on p532009
- Author(s)
  Teng Ma, Shumpei Yamada, Ichwan Solachuddin J. A., Megumi Ostu, Kiyoshi Ohtani, Masa-Aki Ikeda
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21390502
[Presentation] p27Kir1 promoter specifically senses deregulated E2F activity2008
- Author(s)
  Ozono E, Komori H, Ikeda M, Ohtani K
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] The Cdk inhibitor p27Kip1 gene senses pRB dysfunction through E2F.2008
- Author(s)
  Eiko Ozono, Masa-aki Ikeda, Kiyoshi Ohtani
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] 転写因子E2Fによる癌性変化と増殖刺激の識別2008
- Author(s)
  大園瑛子, 池田正明, 井関幸子, 大谷清
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] The Cdk inhibitor p27Kip1 gene senses pRB dysfunction through E2F2008
- Author(s)
  Eiko Ozono, Masa-aki Ikeda, Kiyoshi Ohtani
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] E2FのヘテロダイマーパートナーDP1はE2Fが誘導するアポトーシスとp14ARF遺伝子発現には必要ない2008
- Author(s)
  小森英之, 中村正孝, 大谷清
- Organizer
  第30回日本分子生物学会年回
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] p27^<Kip1> promoter specifically senses deregulated E2F activity.2007
- Author(s)
  Ozono E, Komori H, Ikeda M and Ohtani K
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] E2F heterodimic partner DP1 is not required for E2F-mediated apoptosis and p14ARF gene expression2007
- Author(s)
  Komori, H, Nakamura M, Ohtani K
- Organizer
  The 30th Annual Meeting of Molecular Biology Society of Japan
- Place of Presentation
  Yokohama.
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Presentation] E2FのヘテロダイマーパートナーDP1はE2Fが誘導するアポトーシスとp14^ARF遺伝子発現には必要ない.2007
- Author(s)
  小森英之、中村正孝、大谷清
- Organizer
  第30回日本分子生物学会年回
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19570163
[Presentation] E2FのヘテロダイマーパートナーDP1はE2Fが誘導するアポトーシスとp14ARF遺伝子発現には必要ない2007
- Author(s)
  小森英之、中村正孝、大谷清
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16209054
[Presentation] ヒトT細胞白血病ウイルのがん遺伝子産物Taxによる細胞種特異的細胞周期進行機構の解析
- Author(s)
  吉村友作、大谷清
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] CDK活性がpRBの制御を外れたE2F活性に与える影響の解析
- Author(s)
  城本あゆみ、大谷清
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] 細胞運命決定における転写因子E2FのN末端領域の役割
- Author(s)
  田中達也、大園瑛子、大谷清
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] pRBの機能不全によって特異的に活性化されるARFプロモーターは、がん細胞特異的アプローチに有用である
- Author(s)
  倉吉健太、大谷清
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] pRBの制御を外れたE2F活性はE2FパートナーDP1の要求性が生理的なE2F活性より低い
- Author(s)
  後藤泰子、大谷清
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] ヒトT細胞白血病ウイルスの転写制御因子Taxによるcdk7遺伝子の発現誘導は、Taxによる細胞周期進行の促進に貢献する
- Author(s)
  植野武弘、藤澤順一、大谷清
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] 転写因子E2F1のN末端領域に対する新規相互作用因子の探索と解析
- Author(s)
  神谷侑輝、西谷秀男、大谷清
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] PI3キナーゼ経路はpRBの制御を外れたE2Fによる癌抑制遺伝子の活性化を妨げない
- Author(s)
  大園瑛子、山岡昇司、大谷　清
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌・さっぽろ芸文館・札幌市教育文化会館（札幌市）
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] 転写因子E2F1の新規相互作用因子の探索と解析
- Author(s)
  栄喬大、大園瑛子、西淵剛平、中山潤一、大谷清
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] PI3K経路は制御を外れたE2FによるBim遺伝子発現を抑制しない
- Author(s)
  奥野潤子、大谷清
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] RBの制御を外れたE2F1の実態の解析
- Author(s)
  大園瑛子、山岡昇司、大谷　清
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場・マリンメッセ福岡（福岡市）
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] E2FパートナーDP1の発現制御機構
- Author(s)
  吉田亮輔、大谷清
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] Early in situ detection of virus infection with Raman spectroscopy
- Author(s)
  K. Moor, B. B. Andriana, K. Ohtani, H. Sato
- Organizer
  ICORS2014
- Place of Presentation
  Jena, Germany
- Year and Date
  2014-08-10 – 2014-08-15
- Data Source
  KAKENHI-PROJECT-25560211
[Presentation] 転写因子E2F1の新規相互作用因子DDX5とDDX17の解析
- Author(s)
  藤原裕士、西淵剛平、中山潤一、大谷清
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] ARFプロモーターは細胞傷害性遺伝子のがん細胞特異的発現に有用である
- Author(s)
  倉吉健太、大谷清
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] Distinct regulation of tumor suppressor genes by the transcription factor E2F in response to growth stimulation and oncogenic changes
- Author(s)
  大谷　清
- Organizer
  BIT's 6th Annual World Cancer Congress
- Place of Presentation
  西安（中国）
- Invited
- Data Source
  KAKENHI-PROJECT-24570202
[Presentation] Analysis of the infected cell by Raman spectroscopy in dynamics with using of other methods of comparison
- Author(s)
  K. Moor, K. Ohtani, D. Myrzakozha, O. Zhanserkenova, B. B. Andriana and H. Sato
- Organizer
  BiOS2014
- Place of Presentation
  San Francisco USA
- Data Source
  KAKENHI-PROJECT-25560211
[Presentation] Deregulated E2F Activity: A Novel Means to Discriminate between Cancer Cells and Normal Growing Cells
- Author(s)
  Ohtani K
- Organizer
  PCS Global Cancer Conference-2014
- Place of Presentation
  Athens, Greece
- Year and Date
  2014-10-31 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-24570202

1. NAKAMURA Masataka (30180392)

# of Collaborated Projects: 12 results

# of Collaborated Products: 0 results
2. IKEDA Masaaki (20193211)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
3. IKEDA Yayoi (00202903)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
4. TSURIMOTO Toshiki (30163885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. FUJITA Masatoshi (30270713)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. MURAKAMI Yota (20260622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MASAI Hisao (40229349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. YAMAMURA Yasuko (50146809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 加藤順也 (00273839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. NAKAYAMA Jun-ichi (60373338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SATO Hidetoshi (10300873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. SUGAMURA Kazuo (20117360)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YOSHINAKA Yoshiyuki (30024657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. HARO Hirotaka (10313264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. Warita Tomoko (00753112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. 小布施力史 (00273855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 秋山昌広 (80273837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 春日井昇平 (70161049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 竹下敏一 (60212023)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 井川洋二 (40085618)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 小柳津直樹 (00282773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大坪素秋 (10211799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐藤憲子 (70280956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 割田克彦 (40452669)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
25. ASAO Hironobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KIM Jung?Min

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 荒木啓吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

OTANI Kiyoshi 大谷 清

Ohtani Kiyoshi 大谷 清

OHTANI Kiyoshi 大谷 清

Research Projects

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Regulatory mechanism of deregulated E2F1 activity, which is crucial for tumor suppressionPrincipal Investigator

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Molecular mechanism of E2F regulation of cell proliferation and tumor suppressionPrincipal Investigator

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Molecular mechanism of tumor suppression mediated by the transcription factor E2FPrincipal Investigator

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Cell fate decision mechanism by the transcription factor E2F in cell growth and tumor suppressionPrincipal Investigator

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Analysis of E2F-mediated transcriptional mechanism, which specifically senses oncogenic changesPrincipal Investigator

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G1期におけるDNA複製因子の発現と活性の制御機構の研究Principal Investigator

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OTANI Kiyoshi 大谷清

Ohtani Kiyoshi 大谷清

OHTANI Kiyoshi 大谷清