KINASHI Tatsuo 木梨達雄

… Alternative Names

木梨達雄キナシタツオ

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Researcher Number	30202039
Other IDs
External Links
Affiliation (Current)	2023: 関西医科大学, 医学部, 学長
Affiliation (based on the past Project Information) *help	2023: 関西医科大学, 医学部, 学長 2017 – 2022: 関西医科大学, 医学部, 教授 2005 – 2015: 関西医科大学, 医学部, 教授 2006: Kansai Medical University, Institute for Biomedical Science, Professor, 生命医学研究所, 教授 2000 – 2004: 京都大学, 医学研究科, 教授 … More 1999: 京都大学, 医学研究所, 教授 1994 – 1998: THE INSTITUTE OF MEDICAL SICENCE Assistant Professor, 医科学研究所, 助手 1988 – 1990: 京都大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Cell biology / Basic Section 44010:Cell biology-related / Pathology, Infection/Immunology, and related fields / Immunology / Immunology / Cell biology / 免疫の制御機構 / Experimental pathology Except Principal Investigator Immunology … More / Biological Sciences / Life / Health / Medical informatics / Immunology / Cell biology Less
Keywords	Principal Investigator Rap1 / インテグリン / RAPL / LFA-1 / ICAM-1 / integrin / lymphocyte homing / Mst1 / ケモカイン / リンパ球 … More / kindlin3 / talin / cell adhesion / 細胞接着 / リンパ球ホーミング / 細胞極性 / integrins / PKC / steel factor / VLA-5 / ケモタキシス / 免疫シナプス / アポトーシス / 免疫反応 / VCAM-1 / 接着分子 / 一分子計測 / 免疫学 / lymphocyte / chemokines / Rap 1 / cell polarity / cell migration / RapL / シグナル伝達 / 免疫応答 / 遊走 / cell polarization / chemokine / small GTPase / VLA-4 / inside-outシグナル / 低分子量G蛋白質 / endocytosis / PI3 kinase / cytoplasmic regions / 細胞遊走 / PMA / Rap-1 / ICAM-l / LFA-l / 細胞運動 / エンドサイトーシス / PI3キナーゼ / 細胞内領域 / FcepsilonRI / fibronectin / nxist cells / adhesion molecules / FcεRI / stssl-factor / フィブロネクチン / 肥満細胞 / 細胞接着分子 / Hippoシグナル / Outside-inシグナル / Mst2 / Mat2 / Outside-in シグナル / Mst1,Mst2,インテグリン / ストローマ細胞 / 血管内皮 / 接着 / 発癌 / 増殖 / 抗原提示細胞 / T細胞 / SLC / SDF-1 / APC / IL-2 / JCAM-1 … More Except Principal Investigator IL-5 / Btk / Rap1 / CD38 / サイトカイン / インテグリン / CD40 / チロシンキナーゼ / 細胞接着 / B細胞 / LFA-1 / 接着分子 / Cytokine / B cell differentiation / IL-4 / IL-2 / シグナル伝達 / JAK / トランスジェニックマウス / RAPL / SPA-1 / Integrin / 細胞遊走 / Adhesion / TCR triggering / Anergy / AICD / T cell-APC interaction / Blimp-1 / NF-κB / Stat5 / germline transcripts / ケモカイン / サイトカインレセプター / 胚中心 / Tyrosine kinase / IL-5受容体 / 免疫不全 / 好酸球 / B細胞分化 / インターロイキン5 / 数理モデル / IL-5レセプター / 伴性免疫不全 / IL-5R欠損マウス / 造血幹細胞 / T細胞 / ストロ-マ細胞 / 細胞運動 / 好中球 / 生命情報 / 免疫細胞 / 走化性 / adhesion / chemokine / homing / migration / cell polarization / Tリンパ球 / Bリンパ球分化 / PAPL / 生体内移動 / ホーミング / 遊走 / 細胞極性 / Memory T cells / T cell responsiveness / Tumor immunotherapy / Immune suppression / Leukemia / Tumor immunity / Immune surveillance / 免疫記憶 / 癌抑制遺伝子 / 低分子G蛋白 / アナジー / 抗DNA抗体 / 骨髄幹細胞異常症 / 遺伝子ノックアウトマウス / レセプター編集 / ループス腎炎 / 自己抗体 / 自己免疫病 / G蛋白 / メモリーT細胞 / T細胞応答 / 免疫療法 / 免疫抑制 / 白血病 / がん免疫 / 免疫監視 / Cell migration / Switch recombination / DNA組み換え / stat5 / NF-кB / マウスsIgD+B細胞 / スイッチ組み換え / Follicular mantle zone / X-linked immunodeficiency / CD40とリガンド / 抗体の親和性 / 超変異 / メモリーB細胞 / 細胞死 / クラス変換 / メモリー B細胞 / PI 3-kinase / STAT5 / JAK2 / Cell adhesion / アダプター分子 / 肥満細胞 / BtK / シグナル伝達系 / lgA / STAT path way / anti hIL-5R Ab / IL-5Ralpha deficient mice / eosinophils / late phase allergic response / 遅発型喘息 / 気道過敏性 / 広東住血線虫 / IL-5欠損マウス / STAT系 / 抗ヒトIL-5R抗体 / 遅発型アレルギー反応 / integrin / signal transduction / IL-5 receptor / cytokine receptors / adhesion molecules / cell surface receptors / IL-5Rα欠損マウス / レセプター型チロシンキナーゼ / サイトカイン受容体 / 細胞表面機能分子 / Cytokine receptor / B cell maturation / B cells / Germinal center / Ig-アイソタイプ変換 / サイトカインレセプター / 増殖.分化 / D40 / 増殖・分化 / JAK2 kinase / IL-5 Receptor / Immunodeficiency / GM-CSF / IL-3 / レセプターのクロストーク / タンパク質リン酸化 / JAKキナーゼ / エンハンサー / インターロイキン2の受容体 / 人工突然変異 / リンフォカイン遺伝子 / 免疫グロブリン遺伝子 / IL-5遺伝子 / IL-4遺伝子 / 染色体マップ / トランスジェーニックマウス / IL-2リセプター / Bリンパ球の分化 / 抗体遺伝子D断片 / NK細胞 / トランスジュニックマウス / IL-2R / IgM^+IgG^+B細胞 / クラススイッチ / 骨髄細胞からのリンパ球への分化 / ヒト抗体V_H鎖遺伝子 / trans splicing / double isotype expression / transgenic mouse / integrase family / cDNAクローニング / DNA結合タンパク質 / 抗体遺伝子再構成 / 環状DNA / SーS組換え / ショウジョウバエ / リコンビナ-ゼ / 骨髄多分化能細胞 / VDJ組換 / Bリンパ球 / 秩序 / 形態形成 / 細胞外環境 / シミュレーション / 秩序形成 / イメージング / ゆらぎ / 細胞間相互作用 / 定量的解析 / 細胞外基質 / )細胞間相互作用 / 多細胞 / 細胞移動 / ネコ免疫不全ウィルス / サル免疫不全ウィルス / ヒト免疫不全ウィルス / 後天性免疫不全症 / マウスエイズ / ヒト免疫不全ウイルス / スキッドマウス / キメラウイルス / ネコ免疫不全ウイルス / サル免疫不全ウイルス / レトロウイルス / マウス / STAT / XID / 免疫不全症候群 / ウィルス発癌 / プロテオグリカン / SI増殖因子 / cーkitレセプタ- / 造血支持細胞 / モノクロ-ナル抗体 / 細胞接着分子 / cーKit / エレ-ヌ Less

インテグリンによる細胞相互作用の可塑性と堅牢性の生成メカニズムと生体機能の解明Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kansai Medical University
The single-molecule analysis of dynamic regulation of integrin-dependent adhesion processesPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kansai Medical University
Development of lymphocyte trafficking regulation using single-molecule measurementPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Pathology, Infection/Immunology, and related fields
- Research Institution
  Kansai Medical University
Analysis of spatio-temporal information processing in immune cells
- Principal Investigator
  
  Sawai Satoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  The University of Tokyo
Coordinated regulation of cell adhesion and growth through Rap1 signaling and mammalian Hippo pathway.Principal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kansai Medical University
リンパ球動態異常による免疫系自己の破綻Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
Cross-talk between moving cells and microenvironment as a basis of emerging order in multicellular system
- Principal Investigator
  
  MIYATA TAKAKI
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
Regulatory mechanisms of immune cell trafficking by spatiotemporal control of cell adhesionPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
Integrin dependent cellular growth and functions through the mammalianhippo pathwayPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cell biology
- Research Institution
  Kansai Medical University
Rap1シグナルによるリンパ球動態の制御機構Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
インテグリン接着制御分子欠損による発癌モデルの樹立Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Kansai Medical University
Molecular mechanisms of immune cell traffickingPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  Kansai Medical University
RAPLによるリンパ球極性誘導機構を解明するシステムの樹立Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Cell biology
- Research Institution
  Kyoto University
Regulation and Control of Immune Surveillance
- Principal Investigator
  
  MINATO Nagahiro
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Regulation of integrin-mediated adhesion and immune response by Rap1 and its downstream effector, p30.
- Principal Investigator
  
  KATAGIRI Koko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Regulation of immune cell trafficking by adhesion molecules and immune responsesPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kansai Medical University
  Kyoto University
Study on molecular mechanisms of integrin-regulated adhesion in immune responsesPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Identification and characterization of p30 as a potential effector for Rap1
- Principal Investigator
  
  MAEDA Akito
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
免疫細胞におけるインテグリン活性化シグナルの制御機構と免疫反応調節Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
インテグリン接着性制御による免疫細胞の活性化と動態制御Principal Investigator
- Principal Investigator
  
  木梨達雄
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
LFA-I-mediated regulation of immune response by Rapl.
- Principal Investigator
  
  KATAGIRI Koko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY
Analysis of molecular mechanisms on integrin-family specific adhesionPrincipal Investigator
- Principal Investigator
  
  KINASHI Tatsuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  KYOTO UNIVERSITY
Molecular mechanisms of isotype switch recombination.
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Signaling through surface receptors in immune cells.
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Molecular mechanisms of proliferation and differentiation of germinal center B cells
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Analysis of avidity modulation of integrin beta1Principal Investigator
- Principal Investigator
  
  KINASHI Tasuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  免疫の制御機構
- Research Institution
  The University of Tokyo
免疫担当細胞の活性化と発癌抑制の研究
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokyo
エイズの病態と制御に関する基礎研究エイズの動物モデル
- Principal Investigator
  
  速水正憲
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyoto University
Signal transduction through cell surface receptors
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  The University of Tokyo
Mechanism of pathogenesis of chronic inflamation
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
Studies on the mechanisms of the maturation of germinal center B cells.
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
MECHANISMS OF SIGNAL TRANSDUCTION THROUGH SURFACE RECEPTORS
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  THE UNIVERSITY OF TOKYO
リンパ系幹細胞とストロ-マ細胞間の相互作用に関する研究
- Principal Investigator
  
  西川伸一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kumamoto University
造血支持細胞の役割とその物質的基盤に関する研究
- Principal Investigator
  
  北村幸彦
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Osaka University
免疫系における多様性発現機構の分子遺伝学的研究
- Principal Investigator
  
  本庶佑
- Project Period (FY)
  1986 – 1990
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Research Institution
  Kyoto University

[Book] 細胞工学動く細胞・群れる細胞2014
- Author(s)
  宮田卓樹，柴田達夫，西川正俊，上田昌宏，松井貴輝，片貝智哉，木梨達雄，松村優子，伊藤恭彦，折茂彰，西脇清二，仲嶋一範，林茂生，董波，富樫英，吉野剛史，高橋淑子，西山功一，岡本麻友美，篠田友靖
- Total Pages
  100
- Publisher
  学研メディカル秀潤社
- Data Source
  KAKENHI-ORGANIZER-22111001
[Book] <Seriesモデル動物利用マニュアル>疾患モデルの作成と利用-免疫疾患2011
- Author(s)
  木梨達雄(岩倉洋一郎編)
- Publisher
  インテグリンファミリー(LFA-1,VLA-4ICAM-1,VCAM-1)
- Data Source
  KAKENHI-PROJECT-22370072
[Book] インテグリンファミリー(LFA-1,VLA-4ICAM-1,VCAM-1)<Seriesモデル動物利用マニュアル>疾患モデルの作成と利用-免疫疾患、岩倉洋一郎編、エル・アイ・シー、12011
- Author(s)
  木梨達雄
- Data Source
  KAKENHI-PROJECT-22370072
[Book] <Seriesモデル動物利用マニュアル>疾患モデルの作成と利用-免疫疾患2011
- Author(s)
  木梨達雄(岩倉洋一郎編)
- Publisher
  インテグリンファミリー(LFA-1,VLA-4ICAM-1,VCAM-1)
- Data Source
  KAKENHI-PLANNED-22111003
[Book] 免疫2005 Rap1エフェクター分子RAPLによる免疫細胞の動態制御(岸本忠三編)2004
- Author(s)
  木梨達雄(分担)
- Total Pages
  7
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] Effect of Learning Dataset for Identification of Active Molecules: A Case Study of Integrin αIIbβ3 Inhibitors.2021
- Author(s)
  Kawai K., Tomonou M., Machida Y., Karuo Y., Tarui A. Sato K., Ikeda Y., Kinashi T., Omote M.
- Journal Title
  
  Mol Inform.
  
  Volume: － Issue: 6
- DOI
  10.1002/minf.202060040
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03229
[Journal Article] Kindlin-3 disrupts an intersubunit association in the integrin LFA1 to trigger positive feedback activation by Rap1 and talin1,2021
- Author(s)
  Kondo N, Ueda Y, Kinashi T.
- Journal Title
  
  Sci Signal.
  
  Volume: Vol 14, Issue 686. Issue: 686
- DOI
  10.1126/scisignal.abf2184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03229, KAKENHI-PROJECT-20K07331, KAKENHI-PROJECT-20K07554
[Journal Article] MST1/2 balance immune activation and tolerance by orchestrating adhesion, transcription, and organelle dynamics in lymphocytes.2020
- Author(s)
  Yoshihiro Ueda, Naoyuki Kondo, Tatsuo Kinashi
- Journal Title
  
  Frontier Immunology.
  
  Volume: －
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03229
[Journal Article] 【ジーンハンティングによる炎症・免疫研究の発展】IL-4およびIL-5の遺伝子クローニング2020
- Author(s)
  木梨達雄
- Journal Title
  
  炎症と免疫
  
  Volume: 26(3) Pages: 175-180
- Data Source
  KAKENHI-PROJECT-19H03229
[Journal Article] インテグリン創薬から考える一回膜貫通型タンパク質における創薬ストラテジー2020
- Author(s)
  池田幸樹、木梨達雄
- Journal Title
  
  SAR News
  
  Volume: 39 Pages: 17-23
- Data Source
  KAKENHI-PROJECT-19H03229
[Journal Article] 白血球インテグリンによる接着の制御機構2019
- Author(s)
  木梨達雄
- Journal Title
  
  日本血栓止血学会誌
  
  Volume: 30(4) Pages: 586-595
- NAID
  130007689122
- Data Source
  KAKENHI-PROJECT-19H03229
[Journal Article] 自己免疫疾患のイメージング：自己寛容の成立と維持における細胞間相互作用の可視化2018
- Author(s)
  植田祥啓、近藤直幸、木梨達雄
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 69(4) Pages: 318-325
- Data Source
  KAKENHI-PROJECT-17K19574
[Journal Article] Essential Role of Canonical NF-κB Activity in the Development of Stromal Cell Subsets in Secondary Lymphoid Organs2018
- Author(s)
  Bogdanova Dana、Takeuchi Arata、Ozawa Madoka、Kanda Yasuhiro、Rahman M. Azizur、Ludewig Burkhard、Kinashi Tatsuo、Katakai Tomoya
- Journal Title
  
  The Journal of Immunology
  
  Volume: 201 Issue: 12 Pages: 3580-3586
- DOI
  10.4049/jimmunol.1800539
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05204, KAKENHI-PROJECT-17K19574
[Journal Article] Mode of Tolerance Induction and Requirement for Aire Are Governed by the Cell Types That Express Self-Antigen and Those That Present Antigen.2017
- Author(s)
  Mouri Y, Ueda Y, Yamano T, Matsumoto M, Tsuneyama K, Kinashi T, and Matsumoto M.
- Journal Title
  
  The Journal of Immunology
  
  Volume: 199 Issue: 12 Pages: 3959-3971
- DOI
  10.4049/jimmunol.1700892
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08840, KAKENHI-PROJECT-16K08849, KAKENHI-PROJECT-17K19574, KAKENHI-INTERNATIONAL-16K21731, KAKENHI-ORGANIZER-16H06495, KAKENHI-PLANNED-16H06496, KAKENHI-PROJECT-16H05342
[Journal Article] Sema3e/plexin D1 modulates immunological synapse and migration of thymocytes by Rap1 inhibition2016
- Author(s)
  Ueda Y., Kondo N., Ozawa M., Tomiyama T., Yasuda K., Kinashi T.
- Journal Title
  
  J Immunol.
  
  Volume: 196(7) Issue: 7 Pages: 3019-31
- DOI
  10.4049/jimmunol.1502121
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21524, KAKENHI-PROJECT-25291047
[Journal Article] Enhanced cytotoxic T cell function and inhibition of tumor progression by Mst1 deficiency.2016
- Author(s)
  Yasuda K., Ueda Y., Ozawa M., Matsuda T., Kinashi T.
- Journal Title
  
  FEBS Letter
  
  Volume: 590(1) Issue: 1 Pages: 68-75
- DOI
  10.1002/1873-3468.12045
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25291047
[Journal Article] Hypermethylation of MST1 in IgG4-related autoimmune pancreatitis and rheumatoid arthritis2015
- Author(s)
  Fukuhara T, Tomiyama T, Yasuda K, Ueda Y, Ozaki Y, Son Y, Nomura S, Uchida K, Okazaki K, Kinashi T
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 463(4) Issue: 4 Pages: 968-974
- DOI
  10.1016/j.bbrc.2015.06.043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08657, KAKENHI-PROJECT-26461038, KAKENHI-PROJECT-25291047
[Journal Article] Integrin LFA-1 regulates cell adhesion via transient clutch formation2015
- Author(s)
  Ishibashi, M., Miyanaga, Y., Matsuoka, S., Kozuka, J., Togashi, Y., Kinashi, T. and Ueda, M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 464 Issue: 2 Pages: 459-466
- DOI
  10.1016/j.bbrc.2015.06.155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K14509, KAKENHI-ORGANIZER-22111001, KAKENHI-PROJECT-25291047
[Journal Article] Autotaxin Produced by Stromal Cells Promotes LFA-1－Independent and Rho-Dependent Interstitial T Cell Motility2014
- Author(s)
  Katakai T., Kondo N., Ueda Y., and Kinashi T
- Journal Title
  
  J Immunol
  
  Volume: 193 Issue: 2 Pages: 617-626
- DOI
  10.4049/jimmunol.1400565
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PUBLICLY-25113720, KAKENHI-PROJECT-25291047, KAKENHI-PROJECT-25670101
[Journal Article] Rab13 acts downstream of the kinase Mst1 to deliver the integrin LFA-1 to the cell surface for lymphocyte trafficking.2014
- Author(s)
  Nishikimi A, Ishihara S, Ozawa M, Etoh K, Fukuda M, Kinashi T and Katagiri K
- Journal Title
  
  Sci. Signal.
  
  Volume: Vol. 7,　Issue 336 Issue: 336
- DOI
  10.1126/scisignal.2005199
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111003, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-24590588, KAKENHI-PUBLICLY-25111509, KAKENHI-PROJECT-25291047
[Journal Article] Antigen-specific suppression and immunological synapse formation by regulatory T cells require the mst1 kinase.2013
- Author(s)
  Tomiyama T, Ueda Y, Katakai T, Kondo N, Okazaki K, Kinashi T.
- Journal Title
  
  PLoS One.
  
  Volume: 8(9):e73874. Issue: 9 Pages: e73874-e73874
- DOI
  10.1371/journal.pone.0073874
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-ORGANIZER-24111001, KAKENHI-PUBLICLY-25113720, KAKENHI-PROJECT-25291047, KAKENHI-PROJECT-25670101
[Journal Article] Mst1による胸腺細胞のインテグリン接着制御と選択機構2013
- Author(s)
  植田祥啓、木梨達雄
- Journal Title
  
  医学のあゆみ
  
  Volume: Vol.247,No6 Pages: 565-566
- Data Source
  KAKENHI-PLANNED-22111003
[Journal Article] Dendritic Cells Regulate High-Speed Interstitial T Cell Migration in the Lymph Node via LFA-1/ICAM-1.2013
- Author(s)
  Katakai T, Habiro K, Kinashi T.
- Journal Title
  
  J Immunol
  
  Volume: 191(3) Issue: 3 Pages: 1188-99
- DOI
  10.4049/jimmunol.1300739
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111005, KAKENHI-PROJECT-25291047, KAKENHI-PROJECT-25670101
[Journal Article] Longest neurite-specific activation of Rap1B in hippocampal neurons contributes to polarity formation through RalA and Nore1A in addition to PI3-kinase.2013
- Author(s)
  Nakamura T, Yasuda S, Nagai H, Koinuma S, Morishita S, Goto A, Kinashi T, Wada N.
- Journal Title
  
  Genes Cells.
  
  Volume: 18(11) Issue: 11 Pages: 1020-31
- DOI
  10.1111/gtc.12097
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-PROJECT-23300134, KAKENHI-PROJECT-24657094, KAKENHI-PROJECT-25291047, KAKENHI-PROJECT-25460254
[Journal Article] Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis.2013
- Author(s)
  Chung C, Kim T, Kim M, Kim M, Song H, Kim TS, Seo E, Lee SH, Kim H, Kim SK, Yoo G, Lee DH, Hwang DS, Kinashi T, Kim JM, Lim DS.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 100:19 Issue: 19 Pages: 7732-37
- DOI
  10.1073/pnas.1220603110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-PROJECT-25291047
[Journal Article] Mst1による胸腺細胞のインテグリン接着制御と選択機構2013
- Author(s)
  植田祥啓、木梨達雄
- Journal Title
  
  医学のあゆみ
  
  Volume: Vol.247,No6 Pages: 565-566
- Data Source
  KAKENHI-PROJECT-25291047
[Journal Article] HTLV-1 bZIP Factor Induces Inflammation through Labile Foxp3 Expression.2013
- Author(s)
  Yamamoto-Taguchi N, Satou Y, Miyazato P, Ohshima K, Nakagawa M, Katagiri K, Kinashi T, Matsuoka M.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 9(9):e1003630. Issue: 9 Pages: 1-12
- DOI
  10.1371/journal.ppat.1003630
- NAID
  120005341884
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-PLANNED-22114003, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590588, KAKENHI-PUBLICLY-25111509, KAKENHI-PROJECT-25291047, KAKENHI-PROJECT-25293219, KAKENHI-PROJECT-221S0001
[Journal Article] Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms2012
- Author(s)
  Kyoko Hnanawa-Suetsugu, Mutsuko Kukimoto-Niino, Chiemi Mishima-Tsumagari, Ryogo Akasaka, Noboru Ohsawa, Shun-ichi Sekine, Takuhiro Ito, Naoya Tochio, Seizo Koshiba, Takanori Kigawa, Takaho Terada, Mikako Shirouzu, AkihikoNishikimi, Takehito Uruno, Tomoya Katakai, Tatsuo kinashi, Daisuke Kohda, Yoshinori Tukui, Shigeyuki Yokoyama
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 28:109(9) Pages: 3305-3310
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003
[Journal Article] Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms2012
- Author(s)
  Hanawa-Suetsugu K, Kukimoto-Niino M, Mishima-Tsumagari C, Akasaka R, Ohsawa N, Sekine SI, Ito T, Tochio N, Koshiba S, Kigawa T, Terada T, Shirouzu M, Nishikimi A, Uruno T, Katakai T, Kinashi T, Kohda D, Fukui Y, Yokoyama S
- Journal Title
  
  Proc.Natl.Acad.USA.
  
  Volume: 109 Pages: 3305-3310
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22111001
[Journal Article] Overview of integrin signaling in the immune system.2012
- Author(s)
  Kinashi, T.
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 757 Pages: 261-78
- DOI
  10.1007/978-1-61779-166-6_17
- ISBN
  9781617791659, 9781617791666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370072
[Journal Article] Mst1 regulates integrin-dependent thymocyte trafficking and antigen-recognition in the thymus.2012
- Author(s)
  Ueda Y., Katagiri K., Tomiyama T., Yasuda K., Habiro K., Katakai T., Ikehara S., Matsumoto M, Kinashi T.
- Journal Title
  
  Nat. Commun.
  
  Volume: 3 Issue: 1 Pages: 1098-1098
- DOI
  10.1038/ncomms2105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370072, KAKENHI-PROJECT-23790547, KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111003, KAKENHI-PUBLICLY-23113517, KAKENHI-PUBLICLY-23118520, KAKENHI-ORGANIZER-24111001
[Journal Article] Surf4 modulates STIM1-dependent calcium entry.2012
- Author(s)
  Fujii, Y.　et al
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 422 Issue: 4 Pages: 615-620
- DOI
  10.1016/j.bbrc.2012.05.037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229007, KAKENHI-PROJECT-22370072, KAKENHI-PROJECT-23310134, KAKENHI-PROJECT-23651195, KAKENHI-PROJECT-24650637, KAKENHI-PLANNED-22111003, KAKENHI-PUBLICLY-23114718
[Journal Article] Overview of integrin signaling in the immune system2012
- Author(s)
  Kinashi, T.
- Journal Title
  
  Methods Mol.Biol.
  
  Volume: 757 Pages: 261-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370072
[Journal Article] DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migrataon during immune responses2012
- Author(s)
  Yosuke Harada, Yoshihiko Tanaka, Masao Terasawa, Markus Pieczyk, Katsuyoshi Habiro, Tomoya Katakai, Kyoko Hanawa-Suetsugu, Mutsuko Kukimoto-Niino, Tomoko Nishizaki, Mikako Shirouzu, Xuefeng Duan, Takehito Uruno, Akihiko Nishikimi, Fumiyuki Sanematsu, Shigeyuki Yokoyama, Jens V.Stein, Tatsuo Kinashi, Yoshinori Fukui
- Journal Title
  
  Blood
  
  Volume: (In press) Issue: 19 Pages: 4451-4461
- DOI
  10.1182/blood-2012-01-407098
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003, KAKENHI-PUBLICLY-22117512, KAKENHI-PROJECT-22247017, KAKENHI-PROJECT-22370072, KAKENHI-PROJECT-22790469, KAKENHI-PUBLICLY-23111522, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-24770127, KAKENHI-PLANNED-22133009, KAKENHI-PUBLICLY-23113517, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007
[Journal Article] Reelin controls neuronal positioning by promoting cell-matrix adhesion via inside-out activation of integrin α5β 12012
- Author(s)
  Katsutoshi Sekine, Takeshi Kawauchi, Ken-ichiro Kubo, Takao Honda, Joachim Herz, Mitsuharu Hattori, Tatsuo Kinashi, and Kazunori Nakajima
- Journal Title
  
  Neuron
  
  Volume: 76(2) Issue: 2 Pages: 353-369
- DOI
  10.1016/j.neuron.2012.07.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240041, KAKENHI-PROJECT-22370072, KAKENHI-PROJECT-22390016, KAKENHI-PROJECT-23700417, KAKENHI-PROJECT-24659036, KAKENHI-PROJECT-24700357, KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111003, KAKENHI-PLANNED-22111004, KAKENHI-PUBLICLY-23113725, KAKENHI-PUBLICLY-23123519
[Journal Article] Rap1 and integrin inside-out signaling2012
- Author(s)
  Katagiri K, Kinashi T
- Journal Title
  
  Methods Mol Biol
  
  Volume: 757 Issue: 2 Pages: 279-296
- DOI
  10.1111/j.1365-2567.2005.02214.x
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22111001
[Journal Article] RAPL deficiency caused lymphoproliferative disorders through the mislocalization of p27^<kip>.2011
- Author(s)
  Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K.I, Kinashi, T.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 24-38
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22111003
[Journal Article] RAPL deficiency caused lymphoproliferative disorders through the mislocalization of p27^<kip>2011
- Author(s)
  Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K.I, Kinashi, T.
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 24-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370072
[Journal Article] Deficiency of Rap1-Binding Protein RAPL Causes Lymphoproliferative Disorders through Mislocalization of p27kip12011
- Author(s)
  Katagiri K, Ueda, Y, Tomiyama, T, Yasuda K, Toda Y, Ikehara S, Nakayama KI, Kinashi T
- Journal Title
  
  Immunity
  
  Volume: 34 Pages: 24-38
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22111001
[Journal Article] RAPL deficiency causedlymphoproliferative disordersthrough the mislocalization of p27kip.2011
- Author(s)
  Katagiri, K., Ueda, Y., Tomiyama, T., Yasuda, K., Toda, Y., Ikehara, S., Nakayama, K.I, Kinashi, T.
- Journal Title
  
  Immunity.
  
  Volume: 34 Pages: 1-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370072
[Journal Article] Rap1 controls lymphocyte adhesion cascade and interstitial migration within lymph nodes in RAPL-dependent and -independent manners2010
- Author(s)
  Ebisuno, Y., Katagiri, K., Katakai, T., Ueda, Y., Nemoto, T., Inada, H., Nabekura, J., Okada, T., Kannagi, R., Tanaka, T., Miyasaka, M., Hogg, N., Kinashi, T.
- Journal Title
  
  Blood 28;115(4)
  
  Pages: 804-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060027
[Journal Article] CXCL13production by an established lymph node stromal cell via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways2009
- Author(s)
  Suto H, Katakai T, Sugai M, Kinashi T, Shimizu A.
- Journal Title
  
  Int Immunol. 21(4)
  
  Pages: 467-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Mst1 controls lymphocyte trafficking and interstitial motility within lymph nodes2009
- Author(s)
  Katagiri K, Katakai T, Ebisuno Y, Ueda Y, Okada T, Kinashi T.
- Journal Title
  
  EMBO J. 6:26(9)
  
  Pages: 1319-1331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060027
[Journal Article] CXCL13production by an established lymph node stromal cell via lymphotoxin-beta receptor engagement involves the cooperation of multiple signaling pathways2009
- Author(s)
  Suto H, Katakai T, Sugai M, Kinashi T, Shimizu A.
- Journal Title
  
  Int Immunol 21(4)
  
  Pages: 467-476
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060027
[Journal Article] Rap1-RAPLによるインテグリン制御とリンパ球動態2008
- Author(s)
  木梨達雄
- Journal Title
  
  実験医学 26(14)
  
  Pages: 2174-2175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060027
[Journal Article] Rap1-RAPLによるインテグリン制御とリンパ球動態2008
- Author(s)
  木梨達雄
- Journal Title
  
  実験医学 26(14)
  
  Pages: 2174-2175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Organizer-like reticular stromal cell layer common adult secondary lymphoid organs2008
- Author(s)
  Katakai T, Suto H, Sugai M, Gonda H, Togawa A, Suematsu S, Ebisuno Y, Katagiri K, Kinashi T, Shimizu A.
- Journal Title
  
  JImmunol 181(9)
  
  Pages: 6189-6200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20060027
[Journal Article] Organizer-like reticular stromal cell layer common adult secondary lymphoid organs2008
- Author(s)
  Katakai T, Suto H, Sugai M, Gonda H, Togawa A, Suematsu S, Ebisuno Y, Katagiri K, Kinashi T, Shimizu A.
- Journal Title
  
  JImmunol. 181(9)
  
  Pages: 6189-6200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Integrin regulation of lymphocyte trafficking : Lessons from structural and signaling studies.2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Advances in immunology 93
  
  Pages: 185-227
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] The M-Ras-RA-GEF-2-Rap1 Pathway Mediates Tumor Necrosis Factor α-dependent Regulation of Integrin Activation in Splenocytes2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Mol Bibl Cell 18
  
  Pages: 2949-2945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Integrin regulation of lymphocyte trafficking: lessons from structural and signaling studies2007
- Author(s)
  Kinashi, T
- Journal Title
  
  Adv.Immunol 93
  
  Pages: 185-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Integrin regulation of lymphocyte trafficking:lessons from structural and signaling studies2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Adv.Immunol. 93
  
  Pages: 185-227
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Integrin regulation of lymphocyte trafficking : Lessons from structural and signaling studies.2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Advances in immunology. 93
  
  Pages: 185-227
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Integrin regulation of lymphocyte trafficking : Lessons from structural and signaling studies.2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Advances in immunology 93
  
  Pages: 185-227
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] 低分子量G蛋白質Rap1によるインテグリン制御2007
- Author(s)
  木梨達雄
- Journal Title
  
  蛋白質核酸酵素 52
  
  Pages: 1465-1471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Integrin regulation of lymphccyte trafficking:lessons from structural and signaling studies2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Adv.Immunol 93
  
  Pages: 185-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] 低分子量G蛋白質Rap1によるインテグリン制御2007
- Author(s)
  木梨達雄
- Journal Title
  
  蛋白質核酸酵素 52
  
  Pages: 1465-1471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] The M-Ras-RA-GEF-2-Rap1 Pathway Mediates Tumor Necrosis Factor α-dependent Regulation of Integrin Activation in Splenocytes2007
- Author(s)
  Kinashi, T.
- Journal Title
  
  Mol Biol Cell 18
  
  Pages: 2949-2945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659102
[Journal Article] Adhere upright : A switchblade-like extension of β2 integrins.2006
- Author(s)
  Kinashi, T.
- Journal Title
  
  Immunity 25
  
  Pages: 521-522
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Adhere upright : A switchblade-like extension of β2 integrins.2006
- Author(s)
  Kinashi, T.
- Journal Title
  
  Immunity. 25
  
  Pages: 521-522
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Adhere upright : A switchblade-like extension of β2 integrins.2006
- Author(s)
  Kinashi, T.
- Journal Title
  
  Immunity 25
  
  Pages: 521-522
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Spatiotemporal regulation of the Kinase Mstl by binding protein RAPL is critical for lymphocyte polarity and adhesion.2006
- Author(s)
  Katagiri, K., Imamura, M., Kinashi, T.
- Journal Title
  
  Nature Immunology 7
  
  Pages: 919-927
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Spatiotemporal regulation of the Kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion.2006
- Author(s)
  Katagiri, K., Imamura, M., Kinashi, T.
- Journal Title
  
  Nature Immunology 7
  
  Pages: 919-927
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Spatiotemporal regulation of the Kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion2006
- Author(s)
  Kinashi, T.*
- Journal Title
  
  Nat.Immunol. 7
  
  Pages: 919-927
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Intracellular signaling controlling integrin activation in lymphocytes2005
- Author(s)
  Kinashi, T
- Journal Title
  
  Nat.Rev.Immunol 5
  
  Pages: 546-559
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues.2005
- Author(s)
  Kinashi, T., Katagiri, K.
- Journal Title
  
  Immunology 116
  
  Pages: 164-171
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Intracellular signaling controlling integrin activation in lymphocytes.2005
- Author(s)
  Kinashi, T.
- Journal Title
  
  Nat. Rev. Immunol. 5
  
  Pages: 546-559
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Intracellular signaling controlling integrin activation in Lymphocytes2005
- Author(s)
  Kinashi, T.
- Journal Title
  
  Nat.Rev.Immunol 5
  
  Pages: 546-559
- Data Source
  KAKENHI-PROJECT-17209018
[Journal Article] Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues.2005
- Author(s)
  Kinashi, T. et al.
- Journal Title
  
  Immunology 116
  
  Pages: 164-171
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues2005
- Author(s)
  Kinashi, T., Katagiri, K.
- Journal Title
  
  Immunology 116
  
  Pages: 164-171
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Regulation of immune cell adhesion and migration by regulator of adhesion and cell polarization enriched in lymphoid tissues.2005
- Author(s)
  Kinashi, T., et al.
- Journal Title
  
  Immunology. 116
  
  Pages: 164-171
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Intracellular signaling controlling integrin activation in lymphocytes2005
- Author(s)
  Kinashi, T.
- Journal Title
  
  Nat.Rev.Immunol 5
  
  Pages: 546-559
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL2004
- Author(s)
  Kinashi, T
- Journal Title
  
  Immunology Letter 93
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL2004
- Author(s)
  Kinashi, T
- Journal Title
  
  Immunology Letter 93
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Crucial roles of Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking.2004
- Author(s)
  Katagiri, K., Ohnishi, N., Kabashima, K., Iyoda T, Takeda, N., Shinkai, Y., Inaba, K., Kinashi, T.
- Journal Title
  
  Nat Immunol 5
  
  Pages: 1045-1051
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] Rap1-mediated lymphocyte function-associated antigen-1 activation by the T cell antigen receptor is dependent on phospholipase C-γ1.2004
- Author(s)
  Katagiri, K., Shimonaka, M., Kinashi, T.
- Journal Title
  
  J.Biol.Chem. 220
  
  Pages: 11875-11875
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] Regulation of lymphocyte adhesion and migration by the small GTPass Rapl and its effector molecule, RAPL2004
- Author(s)
  Kinashi, T.
- Journal Title
  
  Immunology Letter 93
  
  Pages: 1-5
- Data Source
  KAKENHI-PROJECT-16657058
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds.2004
- Author(s)
  Kinashi, T., et al.
- Journal Title
  
  Blood. 103
  
  Pages: 1033-1036
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking.2004
- Author(s)
  Katagiri K, Ohnishi N, Kabashima K, Iyoda T, Takeda N, Shinkai Y, Inaba K, Kinashi T.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 1045-1051
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds.2004
- Author(s)
  Kinashi, T., et al.
- Journal Title
  
  Blood 103
  
  Pages: 1033-1036
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation2004
- Author(s)
  Kinashi, T
- Journal Title
  
  Blood 103
  
  Pages: 1033-1036
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation and impaired stabilization of integrin bonds.2004
- Author(s)
  Kinashi, T., Aker, M., Sokolovsky-Eisenberg, M., Grabovsky, V., Tanaka, C., Shamri, R., Feigelson, S., Etzioni, A., Alon, R.
- Journal Title
  
  Blood 103
  
  Pages: 1033-1036
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rap1 activation2004
- Author(s)
  Kinashi, T.
- Journal Title
  
  Blood 103
  
  Pages: 1033-1036
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rapl activation2004
- Author(s)
  Kinashi, T
- Journal Title
  
  Blood 103
  
  Pages: 1033-1036
- Data Source
  KAKENHI-PROJECT-16657058
[Journal Article] Rap1-mediated LFA-1 activation by the T cell antigen receptor is dependent on PLC-γ1.2004
- Author(s)
  Katagiri, K., Shimonaka, K., Kinashi, T.
- Journal Title
  
  J.Biol.Chem. 279
  
  Pages: 11875-11881
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL.2004
- Author(s)
  Kinashi T, Katagiri K.
- Journal Title
  
  Immunol Lett. 93
  
  Pages: 1-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] Regulation of lymphocyte adhesion and migration by the small GTPase Rap1 and its effector molecule, RAPL. (review)2004
- Author(s)
  Kinashi, T., et al.
- Journal Title
  
  Immunol. Lett. 93
  
  Pages: 1-5
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Journal Article] RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.2003
- Author(s)
  Katagiri K, Maeda A, Shimonaka M, Kinashi T.
- Journal Title
  
  Nat.Immunol 4
  
  Pages: 741-748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] The critical cytoplasmic regions of the αL/β2 integrin in Rap1-induced adhesion and migration.2003
- Author(s)
  Tohyama, Y., Katagiri, K., Pardi, R., Lu, C., Springer, T.A., Kinashi, T.
- Journal Title
  
  Mol.Biol.Cell. 14
  
  Pages: 2570-2582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] The critical cytoplasmic regions of the alphaL/beta2 integrin in Rap1-induced adhesion and migration.2003
- Author(s)
  Tohyama Y, Katagiri K, Pardi R, Lu C, Springer TA, Kinashi T.
- Journal Title
  
  Mol Biol Cell. 14
  
  Pages: 2570-2582
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow.2003
- Author(s)
  Shimonaka M, Katagiri K, Nakayama T, Fujita N, Tsuruo T, Yoshie O, Kinashi.T.
- Journal Title
  
  J.Cell.Biol. 161
  
  Pages: 417-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590436
[Journal Article] Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow.2003
- Author(s)
  Shimonaka, M., K.Katagiri, T.Nakayama, N.Fujita, T.Tsuruo, O.Yoshie, T.Kinashi
- Journal Title
  
  J.Cell Biol. 161
  
  Pages: 417-427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Journal Article] RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1.2003
- Author(s)
  Katagiri, K., Maeda, A., Shimonaka, M., Kinashi, T.
- Journal Title
  
  Nat.Immunol. 4
  
  Pages: 741-748
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370112
[Patent] Regulation of Interaction between RAPL and Rap12003
- Inventor(s)
  Kinashi, T., Shikama, H.
- Industrial Property Rights Holder
  ISHIHARA SANGYO KAISHA
- Patent Publication Number
  2004-040302
- Filing Date
  2003-10-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16043224
[Presentation] Kindlin-3 breaks of integrin LFA-1 inhibitory clasp to promote positive feedback activation of LFA-1 by talin1 and Rap12021
- Author(s)
  N. Kondo, Y. Ueda, T. Kinashi,
- Organizer
  The 50th　Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Rap1 facilitates T cell polarity via spatial regulation of MLC and ARAP12021
- Author(s)
  Y. Ueda, K. Higasa, Y. Kamioka, N. Kondo, T. Kinashi
- Organizer
  The 50th　Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Differential requirement of Rap1 and integrin adaptors for distinct modalities of T cell adhesion under shear flow2021
- Author(s)
  Y. Kamioka, Y. Ueda, N. Kondo, T. Kinashi
- Organizer
  The 50th　Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Shootin1b as a clutch molecule for dendritic cell chemotaxis,2020
- Author(s)
  K. Baba, Y. Nagashima, R. Takeuchi, M. Sakai, Y. Higashiguchi, H. Katsuno-Kambe, Y. Ueda, Y. Kamioka, T. Kinashi, N. Inagaki
- Organizer
  CELL BIO virtual 2020(Web Meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Rap1/Talin-1/Kindlin-3を内包する新規ポジティブフィードバック回路によるインテグリン活性化の離散的制御2020
- Author(s)
  近藤直幸、植田祥啓、木梨達雄
- Organizer
  第４３回日本分子生物学会年会、2P-0195、オンライン学会
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Rap1 accelerates T cell polarity formation via the enhancement of Rho-Rock pathways2019
- Author(s)
  Y Ueda, K Higasa, Y Kamioka, N Kondo, T kinashi,
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology 2019（第48回　日本免疫学会学術集会2019） Hamamatsu
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] インテグリン関連疾患治療薬開発に向けた薬剤スクリーニング法の開発,2019
- Author(s)
  Y Ikeda, N Kondo, H Takeda, Y Makita, Y Fukunishi, Y Ueda, K Sato, M Murayama, B Ma, Y Isaka, K Kawai, T Mashimo, Y Kamioka, M Araki, M Omote and T Kinashi
- Organizer
  第10回スクリーニング学研究会
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] 白血球インテグリン接着のメカニズムと炎症性腸疾患への応用2019
- Author(s)
  木梨達雄
- Organizer
  第56回日本消化器免疫学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Roles of Rap1 signaling in lymphocyte homing to peripheral and mucosal lymph nodes2019
- Author(s)
  Y Kamioka, Y Ueda, N Kondo, T Kinashi
- Organizer
  The 48th Annual Meeting of the Japanese Society for Immunology 2019（第48回　日本免疫学会学術集会2019） Hamamatsu
- Data Source
  KAKENHI-PROJECT-19H03229
[Presentation] Roles of Rap1 signaling in immunodeficiency and autoimmunity.2018
- Author(s)
  T Kinashi
- Organizer
  The 9th　Asian Congress of Pediatric Infectious Diseases (ACPID) Dec 2nd. 2018.Fukuoka.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] LFA-1を介したリンパ球細胞接着の一分子解析2018
- Author(s)
  N Kondo, T Kinashi
- Organizer
  分子生物学会, 2018 . Nov. 28-30 Yokohama
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] Rap1 signaling to NDR1 kinase regulate immune synapse formation and cell polarity.2018
- Author(s)
  T Kinashi, N Kondo, Y Ueda, Y Kamioka
- Organizer
  The 9th Xiamen Winter Symposium　Nov.2－5 2018. Xiamen. China.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] Roles of Rap1, Talin-1 and Kindlin-3 in lymphocyte homing to peripheral and mucosal lymph nodes.2018
- Author(s)
  Y Kamioka, Y Ueda, N Kondo, T Kinashi
- Organizer
  The 41th Annual Meeting of the Molecular Biology Society of Japan. Fukuoka
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] W747 talin1 binding site in cytoplasmic domain of the integrin beta2 subunit is crucial for Tcell migration and activatio2018
- Author(s)
  Y Ueda, N Kondo, Y Kamioka, T Kinashi
- Organizer
  The 41th Annual Meeting of the Molecular Biology Society of Japan. Fukuoka
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] Roles of Rap1 and Kindlin-3 in lymphocyte homing to peripheral lymph nodes2017
- Author(s)
  Kamioka Y, Ueda Y, Kondo N, Kinashi T
- Organizer
  The 46th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] Regulation of cell polarization by Rap1 via NDR/Rab8 axis upon chemokine stimulation2017
- Author(s)
  Ueda Y, Kondo N, Kamioka Y, Kinashi T
- Organizer
  The 46th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] NDR1 acts as a molecular hub for the organization of immunological synapse2017
- Author(s)
  Kondo N, Ueda Y, Kinashi T
- Organizer
  The 46th Annual Meeting of the Japanese Society for Immunology
- Data Source
  KAKENHI-PROJECT-17K19574
[Presentation] Imaging of thymocyte trafficking and antigen recognition: roles of Rap1 signaling in self tolerance2015
- Author(s)
  木梨達雄
- Organizer
  第3回御茶ノ水動脈硬化学会
- Place of Presentation
  東京（庭のホテル）
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Roles of Rap1 signaling in immune synapse formation and self-tolerance.2015
- Author(s)
  Kinashi T.
- Organizer
  The 6th Xiamen Winter Symposium
- Place of Presentation
  Xiamen China
- Year and Date
  2015-12-05
- Invited
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Imaging of thymocyte trafficking and antigen recognition: roles of Rap1 signaling in self tolerance2015
- Author(s)
  木梨達雄
- Organizer
  第3回御茶ノ水動脈硬化学会
- Place of Presentation
  東京（庭のホテル）
- Year and Date
  2015-02-28
- Invited
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Single-Molecule Analysis of LFA-1/ICAM-1 Binding in Lymphocyte.2014
- Author(s)
  Kinashi T., Kondo N.
- Organizer
  Biophysical Society 58th Annual Meeting.
- Place of Presentation
  the Moscone Center, San Francisco USA.
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] 動く細胞と場のクロストークによる秩序の生成2014
- Author(s)
  宮田卓樹, 上田昌宏, 木梨達雄, 仲嶋一範, 西脇清二, 林茂生, 栗山正, 中井淳一, 佐藤純, 若松義雄, 澤井哲, 西山功一, 高木新, 日比正彦, 長山和亮, 戎家美紀, 渡邉正勝, 富樫英, 西田満, 松井貴輝
- Organizer
  第8回領域班会議
- Place of Presentation
  慶応大学日吉キャンパス往来舎（横浜市）
- Data Source
  KAKENHI-ORGANIZER-22111001
[Presentation] Single-Molecule Analysis of LFA-1/ICAM-1 Binding in Lymphocyte.2014
- Author(s)
  Kinashi T., Kondo N.
- Organizer
  Biophysical Society 58th Annual Meeting.
- Place of Presentation
  the Moscone Center, San Francisco USA.
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Live-imaging analysis of LFA-1/ICAM-1 and roles of Mst1 in immunological synapse formation using primary T lymphocytes2013
- Author(s)
  Kondo N., Ueda Y., Katakai T., Kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Regulation of Lymphocyte “Stop and Go”: Analysis of Lymphocyte Trafficking using Live Imaging Techniques2013
- Author(s)
  Tatsuo Kinashi
- Organizer
  第23回CDBミーティング”Building multicellular systems from cellular cross-talk”
- Place of Presentation
  神戸　理化学研究所神戸研究所
- Year and Date
  2013-01-22
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] 接着制御破綻による自己免疫発症の機序2013
- Author(s)
  木梨達雄
- Organizer
  第１６回中国地区小児免疫宅物療法研究会
- Place of Presentation
  広島　リーガロイヤルホテル広島
- Year and Date
  2013-03-02
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Crucial roles of Mst1for antigen recognition during T cell-APC interactions.2013
- Author(s)
  Ozawa M., Katakai T., Ueda Y., Lee S.I., Kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] LFA-1/ICAM-1 によるリンパ球の‘stop and go’ : ライブイメージングによるリンパ球の動態解析2013
- Author(s)
  木梨達雄
- Organizer
  第51 回日本生物物理学会年会
- Place of Presentation
  国立京都国際会館（京都市）
- Invited
- Data Source
  KAKENHI-ORGANIZER-22111001
[Presentation] Environmental control of high-speed T cell migration in the lymph node2013
- Author(s)
  Katakai T., kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Regulation of Lymphocyte "Stop and Go": Analysis of Lymphocyte Trafficking using Live Imaging Techniques2013
- Author(s)
  Kinashi T., Katakai T.,Ueda Y., Kondo N..
- Organizer
  第23回CDBミーティング"Building multicellular systems from cellular cross-talk
- Place of Presentation
  神戸
- Year and Date
  2013-01-22
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Crucial roles of Mst1for antigen recognition during T cell-APC interactions.2013
- Author(s)
  Ozawa M., Katakai T., Ueda Y., Lee S.I., Kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Live-imaging analysis of LFA-1/ICAM-1 and roles of Mst1 in immunological synapse formation using primary T lymphocytes2013
- Author(s)
  Kondo N., Ueda Y., Katakai T., Kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Environmental control of high-speed T cell migration in the lymph node2013
- Author(s)
  Katakai T., kinashi T.
- Organizer
  日本免疫学会総会第42回学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] 動く細胞と場のクロストークによる秩序の生成2013
- Author(s)
  宮田卓樹, 上田昌宏, 木梨達雄, 仲嶋一範, 西脇清二, 林茂生, 栗山正, 中井淳一, 佐藤純, 若松義雄, 澤井哲, 西山功一, 高木新, 日比正彦, 長山和亮, 戎家美紀, 渡邉正勝, 富樫英, 西田満, 松井貴輝
- Organizer
  第7回領域班会議
- Place of Presentation
  名古屋大学野依学術記念館（名古屋市）
- Data Source
  KAKENHI-ORGANIZER-22111001
[Presentation] Regulation of thymocyte trafficking and antigen recognition within thymic tissues through integrins and Rap1 effector Mst12012
- Author(s)
  Yoshihiro Ueda, Koko Katagiri, Takashi Tomiyama, Kaneki Yasuda, Katsuyoshi Habiro, Tomoya Katakai, Susumu Ikehara, Tatsuo Kinashi
- Organizer
  40th keystone symposia
- Place of Presentation
  Breckenridge, USA
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus.2012
- Author(s)
  Tatsuo Kinashi
- Organizer
  第41回日本免疫学会学術集会シンポジウム
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Rap1シグナルによるリンパ球動態の制御機構2012
- Author(s)
  木梨達雄
- Organizer
  新学術研究「動く細胞と場のクロストークによる秩序の生成」第1回公開シンポジウム「動く細胞と場を読む」
- Place of Presentation
  名古屋大学
- Year and Date
  2012-01-27
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] 関西医科大学附属生命医学研究所分子遺伝学部門免疫細胞の組織内移動と停止の制御2012
- Author(s)
  木梨達雄、片貝智哉、植田祥啓、羽廣克嘉
- Organizer
  イメージング手法による接着制御の解析バイオイメージング学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-08-28
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Regulation of immune cell trafficking and antigen recognition through Rap1 signaling2012
- Author(s)
  Kinashi Tatsuo
- Organizer
  The 21st Hot Spring Harbor Symposium jointly with 9th Global COE International Symposium : Cell Migration in Biology and Medicine
- Place of Presentation
  Kyusyu Univ.Fukuoka Japan
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] High-speed interstitial T cell migration in lymph node parenchyma requires LFA-1-dependent and -independent mechanisms controlled by stromal cells2012
- Author(s)
  Tomoya Katakai, Tatsuo Kinashi
- Organizer
  40th keystone symposia
- Place of Presentation
  Breckenridge, USA
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus.2012
- Author(s)
  Tatsuo　Kinashi
- Organizer
  第41回日本免疫学会学術集会シンポジウム
- Place of Presentation
  神戸　神戸国際会議場
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] 免疫細胞の組織内移動と停止の制御：イメージング手法による接着制御の解析2012
- Author(s)
  木梨達雄
- Organizer
  バイオイメージング学会
- Place of Presentation
  京都　国立京都国際会館
- Year and Date
  2012-08-28
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Two-step model of T cell-DC primary contacts and roles of integrin-regulatory Mst12012
- Author(s)
  Habiro Katsuyoshi, Katakai Tomoya, Kinashi Tatsuo
- Organizer
  40th keystone symposia
- Place of Presentation
  Breckenridge, USA
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus.2012
- Author(s)
  KINASHI Tatsuo
- Organizer
  第41回日本免疫学会学術集会シンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] イメージングによるリンパ球組織内移動の調節とその破綻の解析2011
- Author(s)
  木梨達雄
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル・東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Crucial roles of Mst1 and RAPL (RASSF5b) in lymphocyte adhesion and proliferation2011
- Author(s)
  Kinashi T., Katagiri K., Katakai T., Ueda Y., Habiro K.
- Organizer
  The second workshop on the HIPPO tumor suppressor pathway
- Place of Presentation
  Rome, Italy
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Crucial roles of Mst1 and RAPL (RASSF5) in lymphocyte adhesion and proliferation2011
- Author(s)
  Tatsuo Kinashi, Koko Katagiri, Katakai Tomoya, Yoshihiro Ueda, Katsuyoshi Habiro
- Organizer
  2nd International RASSF Symposium
- Place of Presentation
  Oxford England
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] High-speed interstitial T cell migration within lymph node parenchyma involves LFA-1-dependent and -independent motility modes2011
- Author(s)
  Katakai Tomoya, Tatuso Kinashi
- Organizer
  2011 The Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe Chiba Japan
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Mst1 regulates thymocyte trafficking and antigen recognition within thymic tissues.2011
- Author(s)
  Ueda Y., Katagiri K., Tomiyama T., Yasuda K., Habiro K., Katakai T., Ikehara S., Kinashi T..
- Organizer
  2011 The Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Chiba Japan
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Crucial roles of Mst1 and RAPL (RASSF5) in lymphocyte adhesion and proliferation.2011
- Author(s)
  Kinashi T., Katagiri K., Katakai T., Ueda Y., Habiro K..
- Organizer
  2nd International RASSF Symposium
- Place of Presentation
  Oxford UK
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Mst1 regulates thymocyte trafficking and antigen recognition within thymic tissues2011
- Author(s)
  Ueda Yoshihiro1, Katagiri Koko2, Tomiyama Takashi1, Yasuda Kaneki1, Habiro Katsuyoshi1, Katakai Tomoya1, Ikehara Susumu3, Kinashi Tatsuo1, (1Department of Molecular Genetics, Institute of Biomedical Science, Kansai Medical University. 2Department of Bioscience, School of Science and Technology, Kwansei Gakuin University. 3Department of Stem Cell Disorders. Kansai Medical University.)
- Organizer
  2011 The Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe Chiba Japan
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Two-step model of T cell-DC primary contacts and roles of integrin-regulatory Mst12011
- Author(s)
  Habiro Katsuyoshi, Katakai Tomoya, Kinashi Tatsuo
- Organizer
  2011 The Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Makuhari Messe Chiba Japan
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Cell migration and antigen recognition within lymph nodes and thymus2011
- Author(s)
  Tatsuo Kinashi, Koko Katagiri, Katakai Tomoya, Yoshihiro Ueda, Katsuyoshi Habiro
- Organizer
  London Research Institute Cancer Research UK
- Place of Presentation
  London UK
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Crucial roles of Mstl and RAPL (RASSF5b) in lymphocyte adhesion and proliferation2010
- Author(s)
  Tatsuo Kinashi, Koko Katagiri, Katakai Tomoya, Yoshihiro Ueda, Katsuyoshi Habiro
- Organizer
  The second workshop on the HIPPO tumor suppressor pathway
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Distinct signaling processes in regulation of lymphocyte arrest and adhesion strengthening under shear flow2010
- Author(s)
  T.Kinashi, K.Katagiri, T.Katakai, Y.Ueda
- Organizer
  The 16th International Vascular Biology Meeting
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Crucial roles of Mst1 and RAPL (RASSF5b) in lymphocyte adhesion and proliferation2010
- Author(s)
  Tatsuo Kinashi, Koko Katagiri, Katakai Tomoya, Yoshihiro Ueda, Katsuyoshi Habiro
- Organizer
  The second workshop on the HIPPO tumor suppressor pathway
- Place of Presentation
  Rome, Italy
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Distinct signaling processes in regulation of lymphocyte arrest and adhesion strengthening under shear flow2010
- Author(s)
  Kinashi.T.
- Organizer
  The 16th International Vascular Biology Meeting Los
- Place of Presentation
  Angeles,USA
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Distinct signaling processes in regulation of lymphocyte arrest and adhesi on strengthening under shear flow2010
- Author(s)
  T.Kinashi, K.Katagiri, T.Katakai, Y.Ueda
- Organizer
  The 16th International Vascular Biology Meeting
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] RAPL signaling in regulation of immune cell traffic and proliferation2009
- Author(s)
  Kinashi T
- Organizer
  First International Symposium of Clinical and Biological Implications for the role of the RASSF (the Ras association domain family) family of tumor suppressor proteins
- Place of Presentation
  Canada
- Data Source
  KAKENHI-PROJECT-19659102
[Presentation] Regulation of lymphocyte trafficking by RAPL and MST1 signaling2009
- Author(s)
  Kinashi T.
- Organizer
  The 2009 FASEB(Federation of American Societies for Experimental Biology)Summer Research Conference, Signal Transduction in The Immune System
- Place of Presentation
  Snowmass, Colorado
- Data Source
  KAKENHI-PROJECT-20060027
[Presentation] Regulation of lymphocyte trafficking by RAPL and Mst1 signaling2009
- Author(s)
  Kinashi T.
- Organizer
  The 21^<st> IUBMB and the 12^<th> FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  Shanghai China
- Data Source
  KAKENHI-PROJECT-20060027
[Presentation] Lymphocyte adhesion cascade regulated by Rap1 signaling2008
- Author(s)
  Kinashi T
- Organizer
  The 2008 ASIP Annual Meeting at Experimental Biology 2008
- Place of Presentation
  San Diego USA
- Data Source
  KAKENHI-PROJECT-20060027
[Presentation] The Rapl-RAPL-Mstl signaling2007
- Author(s)
  Kinashi, T., Katagiri, K., Ebisuno, Y.
- Organizer
  Gordon Research Conference:Mechanisms of Cell Signaling
- Place of Presentation
  Oxford,United Kingdom
- Data Source
  KAKENHI-PROJECT-17209018
[Presentation] The Rap1-RAPL-Mst1 signaling2007
- Author(s)
  Kinashi T Katagiri, K.Ebisuno, Y.
- Organizer
  Gordon Research Conference:Mechanisms of Cell Signaling
- Place of Presentation
  Oxford,United Kingdom
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209018
[Presentation] Regulation of integrin-dependent lymphocyte adhesion by Rap1-RAPLsignaling2007
- Author(s)
  Kinashi, T
- Organizer
  The 37th Annual Meeting of the Japanese Society for Immunology
- Place of Presentation
  Tokyo Japan
- Data Source
  KAKENHI-PROJECT-19659102
[Presentation] The Rapl-RAPL-Mstl signaling2007
- Author(s)
  Kinashi T Katagiri, K. Ebisuno,Y
- Organizer
  Gordon Research Conference : Mec hanisms of Cell Signaling
- Place of Presentation
  Oxford, United Kingdom
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209018
[Presentation] SEMA3E/Plexin D1 axis controls thymocyte sdhesion and polarization by modulating the Rap1signaling pathway
- Author(s)
  Ueda Y., Kondo N.,Ozawa M., Katakai T., and Kinashi T.
- Organizer
  第43回免疫学会学術集会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Rap1シグナルによる胸腺細胞の動態制御機構
- Author(s)
  木梨達雄
- Organizer
  酵素学研究拠点シンポジウム
- Place of Presentation
  徳島大学藤井節郎記念医学センター
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Regulation of Lymphocyte “Stop and Go”: Analysis of Lymphocyte Trafficking using Live Imaging Techniques
- Author(s)
  Tatsuo Kinashi
- Organizer
  第23回CDBミーティング”Building multicellular systems from cellular cross-talk”
- Place of Presentation
  理化学研究所神戸研究所
- Invited
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Rap1シグナルによる胸腺細胞の動態制御機構
- Author(s)
  木梨達雄
- Organizer
  酵素学研究拠点シンポジウム
- Place of Presentation
  徳島大学藤井節郎記念医学センター
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Visualization of thymocyte trafficking and selection processes: the importance of Rap1 signaling and integrins
- Author(s)
  Kinashi T., Ueda Y., Kondo N.
- Organizer
  International Symposium on Multi-dimensional Fluorescence Live Imaging of Cellular Functions and Molecular Activities
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2015-01-26 – 2015-01-28
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Regulation of lymphocyte migration and immunological synapse formation through Rap1 signaling.
- Author(s)
  Kinashi T., Katakai T., Ueda Y., Kondo N.
- Organizer
  九州大学生体防御医学研究所国際シンポジウム"Recent Advances in Immunology and Inflammation 2014"
- Place of Presentation
  福岡(九州大学病院キャンパス　コラボステーションI 2F 視聴覚ホール）
- Year and Date
  2014-11-07 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Regulation of Lymphocyte “Stop and Go” via LFA-1 and ICAM-1: Lymphocyte Trafficking Analysis using Live Imaging Techniques
- Author(s)
  Kinashi T., Katakai T., Ueda Y., Kondo N.
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] Visualization of thymocyte trafficking and selection processes: the importance of Rap1 signaling and integrins
- Author(s)
  Kinashi T., Ueda Y., Kondo N.
- Organizer
  International Symposium on Multi-dimensional Fluorescence Live Imaging of Cellular Functions and Molecular Activities
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2015-01-26 – 2015-01-28
- Invited
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] Regulation of Lymphocyte “Stop and Go” via LFA-1 and ICAM-1: Lymphocyte Trafficking Analysis using Live Imaging Techniques
- Author(s)
  Kinashi T., Katakai T., Ueda Y., Kondo N.
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-25291047
[Presentation] 免疫細胞の組織内移動と停止の制御：イメージング手法による接着制御の解析
- Author(s)
  木梨達雄
- Organizer
  バイオイメージング学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-22370072
[Presentation] Regulation of lymphocyte migration and immunological synapse formation through Rap1 signaling.
- Author(s)
  Kinashi T., Katakai T., Ueda Y., Kondo N.
- Organizer
  九州大学生体防御医学研究所国際シンポジウム"Recent Advances in Immunology and Inflammation 2014"
- Place of Presentation
  福岡(九州大学病院キャンパス　コラボステーションI 2F 視聴覚ホール）
- Year and Date
  2014-11-07 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] SEMA3E/Plexin D1 axis controls thymocyte sdhesion and polarization by modulating the Rap1signaling pathway
- Author(s)
  Ueda Y., Kondo N.,Ozawa M., Katakai T., and Kinashi T.
- Organizer
  第43回免疫学会学術集会
- Place of Presentation
  京都（国立京都国際会館）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PLANNED-22111003
[Presentation] 接着制御破綻による自己免疫発症の機序
- Author(s)
  木梨達雄
- Organizer
  第１６回中国地区小児免疫宅物療法研究会
- Place of Presentation
  リーガロイヤルホテル広島
- Data Source
  KAKENHI-PROJECT-22370072

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KINASHI Tatsuo 木梨 達雄

木梨 達雄 キナシ タツオ

Research Projects

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Co-Researchers

インテグリンによる細胞相互作用の可塑性と堅牢性の生成メカニズムと生体機能の解明Principal Investigator

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The single-molecule analysis of dynamic regulation of integrin-dependent adhesion processesPrincipal Investigator

Principal Investigator

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Development of lymphocyte trafficking regulation using single-molecule measurementPrincipal Investigator

Principal Investigator

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Principal Investigator

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Coordinated regulation of cell adhesion and growth through Rap1 signaling and mammalian Hippo pathway.Principal Investigator

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リンパ球動態異常による免疫系自己の破綻Principal Investigator

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Regulatory mechanisms of immune cell trafficking by spatiotemporal control of cell adhesionPrincipal Investigator

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Integrin dependent cellular growth and functions through the mammalianhippo pathwayPrincipal Investigator

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Rap1シグナルによるリンパ球動態の制御機構Principal Investigator

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インテグリン接着制御分子欠損による発癌モデルの樹立Principal Investigator

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Molecular mechanisms of immune cell traffickingPrincipal Investigator

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RAPLによるリンパ球極性誘導機構を解明するシステムの樹立Principal Investigator

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KINASHI Tatsuo 木梨達雄

木梨達雄キナシタツオ