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FUKUMOTO Seiji  福本 誠二

ORCIDConnect your ORCID iD *help
Researcher Number 30202287
Other IDs
Affiliation (based on the past Project Information) *help 2020 – 2023: 徳島大学, 先端酵素学研究所, 特任教授
2016 – 2019: 徳島大学, 先端酵素学研究所(オープンイノベ), 特任教授
2015: 徳島大学, 藤井節郎記念医科学センター, 特任教授
2002 – 2012: The University of Tokyo, Department of Medicine, Lecturer, 医学部附属病院, 講師
2011: 東京大学, 医学部・附属病院, 講師 … More
2008: The University of Tokyo, 医学部・附属病院, 講師
2006: 東京大学医学部附属病院, 講師
2001: 東京大学, 医学部・附属病院, 助手
2001: The University of Tokyo, Hospital, Lecturer, 医学部・附属病院, 講師
1999 – 2000: 東京大学, 医学部・附属病院・分院, 講師
1998 – 2000: Department of Laboratory Medicine, The University of Tokyo Branch Hospital, Lecturer, 医学部・附属病院分院, 講師
1998: 東京大学, 医学部・附属病院, 講師
1997: 東京大学, 医学部附属病院分院, 助手
1996 – 1997: 東京大学, 医学部附属病院(分), 助手
1996: 東京大学, 医学部・附属病院, 助手
1995 – 1996: 東京大学, 医学部・附属病院(分), 助手
1994: 東京大学, 医学部(分), 助手 Less
Review Section/Research Field
Principal Investigator
Endocrinology / 内分泌・代謝学 / Basic Section 53040:Nephrology-related / Endocrinology
Except Principal Investigator
内分泌・代謝学 / Endocrinology / Endocrinology / Metabolomics
Keywords
Principal Investigator
FGF23 / カルシウム感知受容体 / 低リン血症 / 骨軟化症 / 副甲状腺ホルモン受容体 / 偽性副甲状腺機能低下症 / リン / Hypocalcemia / Hypercalcemia / 低カルシウム血症 … More / 高カルシウム血症 / Calcium-sensing receptor / プロモーター / PTH / Pseudohypoparathyroidism / くる病 / 腫瘍性骨軟化症 / FGF / 高リン血症 / 寿命 / PHEX / 繊維芽細胞増殖因子受容体 / 線維芽細胞増殖因子受容体 / 線維芽細胞増殖因子23 / Hyperphosphatemia / Hypophosphatemia / FGF-23 / ノックアウトマウス / 慢性腎不全 / Tumoral calcinosis / mutation / calcium-sensing receptor / 遺伝子変異 / Mutation / Cloning / Promoter / 原発性副甲状腺機能亢進症 / 副甲状腺ホルモン関連蛋白 / 自己抗体 / 変異 / クローニング / PTHrP receptor / Ca感知受容体 / PTHrP受容体 / Molecular biology / PTH receptor / 分子生物学 / 二次性副甲状腺機能亢進症 / 抗体 / 慢性腎臓病 / 腫瘍状石灰化症 / 翻訳後修飾 / O型糖鎖 / プロテアーゼ / FGF受容体 / Klotho / ホルモン / 副甲状腺ホルモン … More
Except Principal Investigator
骨芽細胞 / osteoblast / Smad / 骨粗鬆症 / BMP / osteoporosis / 骨形成 / PPARγ / aging / bone formation / integrin / 加齢 / インテグリン / 脂肪細胞 / FAK / collagen / 骨髄間質細胞 / コラーゲン / 老化 / 脂質 / シグナル伝達 / 遺伝子 / tumoral calcinosis / FGF-23 / adipocyte / SIP-1 / DDR / MAPキナーゼ / interleukin-11 / TGF-β / 基質蛋白 / 骨-脂肪組織連関 / 骨ー脂肪組織関連 / 骨代謝学 / 骨・カルシウム代謝異常 / 骨代謝 / Pim-2 / 破骨細胞 / 骨髄腫 / Wntシグナル / インターロイキン-11 (IL-11) / acromegaly / vitamin D metabolism / phosphate metabolism / 末端肥大症 / ビタミンD代謝 / リン代謝 / leptin / osteocalcin / bone marrow stromal c / adiponectin / レプチン / オステオカルシン / アデイポネクチン / transgenio mine / bone marrwo stromal cell / トランスジェニックマウス / インターロイキン11 / receptor tyrosine kinase / myoblast / チロシンキナーゼ受容体 / 筋芽細胞 / bone metastasis / ERK / 骨転移 / MAP kinase / 分化 / MAPK / bone marrow cells / adhesion molecules / matrix proteins / 骨髄細胞 / 接着分子 / 基質タンパク / TGF-beta / senile osteoporosis / bone matrix / decorin / TGF-β(transforming growth factor-β) / ビスフォスフォネート / デコリン受容体 / TGF-β受容体 / 老人性骨粗鬆症 / 骨基質 / デコリン / differentiation / growth factor / matrix protein / アルカリフォスファターゼ / TGF-β(transforming growth factor) / チロシンリン酸化 / focal adhesion kinese / 細胞分化 / 成長因子 / 高リン血症 / 酸化ストレス / 骨、ミネラル代謝 / ミネラル代謝 / 内分泌学 Less
  • Research Projects

    (22 results)
  • Research Products

    (66 results)
  • Co-Researchers

    (15 People)
  •  Research on phosphate-sensing mechanism that is essential for normal life expectancyPrincipal Investigator

    • Principal Investigator
      福本 誠二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      The University of Tokushima
  •  Study on the actions of phosphate as a first messengerPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      The University of Tokushima
  •  Role and mechanism of action of IL-11 on the regulation of bone and adipose tissue interaction

    • Principal Investigator
      MATSUMOTO Toshio
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokushima
  •  Elucidation of molecular mechanism of the regulation of skeletal homeostasis, and development of new therapeutic approaches against skeletal disorders

    • Principal Investigator
      MATSUMOTO Toshio
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokushima
  •  Analyses of oxidative stress Mechanisms in bone mineral disorders

    • Principal Investigator
      TAGUCHI Manabu
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Regulatory mechanisms of mineral homeostasis by FGF23Principal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Involvement of fibroblast growth factor 23 in bone and mineral metabolism and its disordersPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Physiological and pathological involvement of FGF-23 in mineral metabolism in human

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Okinaka Memorial Institute for Medical Research
  •  Research on regulatory mechanisms and their derangements of calcium and phosphate metabolismPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Regulation by adipocytokines of bone metabolism

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      Okinaka Memorial Institute for Medical Research
      The University of Tokyo
  •  Elucidetion of pathogeness of derangements in Calcinm metabolismPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Role of bone marrow adipogenesis for bone formation and its abnormality in senile osteoporosis

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  The mechanism of osteoblastic differentiotion regulated by BMP-dependent transcription factors-A basic study directed to development of a treatment for senile osteoporosis

    • Principal Investigator
      NAKAYAMA Konosuke
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Cell-matrix interaction in the regulation of bone metabolism and its disorder in involutional osteoporosis

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      University of Tokyo
  •  Study on signal transduction system through calcium-sensing receptorPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokyo
  •  Research on signal transduction through parathyroid hormone(PTH)/PTH-related protein receptorPrincipal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Cell-matrix interaction in osteoblastic differentiation and its disorder in involutional osteoporosis

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of TOkyo
  •  Molecular biological analysis of signal transduction system through parathyroid hormone receptor. Evaluation of parathyroid hormone receptor in patients with pseudohypoparathyroidism.Principal Investigator

    • Principal Investigator
      FUKUMOTO Seiji
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Regulation of osteoblastic differentiation and its implication in involutional osteoporosis

    • Principal Investigator
      TAKEUCHI Yasuhiro
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  偽性副甲状腺機能低下症患者における副甲状腺ホルモン受容変異の検討Principal Investigator

    • Principal Investigator
      福本 誠二
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      The University of Tokyo
  •  Role of matrix proteins in the local regulation of bone metabolism and its abonomalities in osteoporosis

    • Principal Investigator
      MATSUMOTO Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo
  •  Development of a new therapeutic approach for senile osteoporosis using bone matrix deoorin

    • Principal Investigator
      MATSUMOTO Toshio
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      内分泌・代謝学
    • Research Institution
      University of Tokyo School

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] Single-cell RNA sequencing identifies Fgf23-expressing osteocytes in response to 1,25-dihydroxyvitamin D3 treatment2023

    • Author(s)
      Ayako Hanai, Ayako Kawabata, Kenta Nakajima, Kazuhiro Masuda, Itaru Urakawa, Masahiro Abe, Yuji Yamazaki, Seiji Fukumoto
    • Journal Title

      Front Physiol

      Volume: 14 Pages: 1102751-1102751

    • DOI

      10.3389/fphys.2023.1102751

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22H03089
  • [Journal Article] Phosphate-Sensing2022

    • Author(s)
      Takashi Yuichi、Fukumoto Seiji
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 1362 Pages: 27-35

    • DOI

      10.1007/978-3-030-91623-7_4

    • ISBN
      9783030916213, 9783030916237
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H03676
  • [Journal Article] FGF23 and Hypophosphatemic Rickets/Osteomalacia2021

    • Author(s)
      Takashi Yuichi、Kawanami Daiji、Fukumoto Seiji
    • Journal Title

      Current Osteoporosis Reports

      Volume: 19 Issue: 6 Pages: 669-675

    • DOI

      10.1007/s11914-021-00709-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08714, KAKENHI-PROJECT-19H03676, KAKENHI-PROJECT-20K17301
  • [Journal Article] Skeletal FGFR1 signaling is necessary for regulation of serum phosphate level by FGF23 and normal life span2021

    • Author(s)
      Takashi Yuichi、Sawatsubashi Shun、Endo Itsuro、Ohnishi Yukiyo、Abe Masahiro、Matsuhisa Munehide、Kawanami Daiji、Matsumoto Toshio、Fukumoto Seiji
    • Journal Title

      Biochemistry and Biophysics Reports

      Volume: 27 Pages: 101107-101107

    • DOI

      10.1016/j.bbrep.2021.101107

    • NAID

      120007146085

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03676, KAKENHI-PROJECT-20K17301
  • [Journal Article] How do we sense phosphate to regulate serum phosphate level?2020

    • Author(s)
      Seiji Fukumoto, Yuichi Takashi, Maria Tsoumpra, Shun Sawatsubashi, Toshio Matsumoto
    • Journal Title

      Journal of Bone and Mineral Metabolism

      Volume: 38 Issue: 1 Pages: 1-6

    • DOI

      10.1007/s00774-019-01066-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19518, KAKENHI-PROJECT-19H03676, KAKENHI-PROJECT-18K15980, KAKENHI-PROJECT-18K16236, KAKENHI-PROJECT-18KT0024
  • [Journal Article] Phosphate-sensing and regulatory mechanism of FGF23 production2020

    • Author(s)
      Takashi Y.、Fukumoto S.
    • Journal Title

      Journal of Endocrinological Investigation

      Volume: - Issue: 7 Pages: 877-883

    • DOI

      10.1007/s40618-020-01205-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15980, KAKENHI-PROJECT-19H03676
  • [Journal Article] Fibroblast growth factor receptor as a potential candidate for phosphate sensing2020

    • Author(s)
      Takashi Yuichi、Fukumoto Seiji
    • Journal Title

      Current Opinion in Nephrology & Hypertension

      Volume: 29 Issue: 4 Pages: 446-452

    • DOI

      10.1097/mnh.0000000000000618

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15980, KAKENHI-PROJECT-19H03676
  • [Journal Article] Persistent activation of calcium-sensing receptor suppresses bone turnover, increases microcracks and decreases bone strength2019

    • Author(s)
      Bingzi Dong, Itsuro Endo, Yukiyo Ohnishi, Yukari Mitsui, Kiyoe Kurahashi, Mai Kanai, Masahiro Hiasa, Jumpei Teramachi, Hirofumi Tenshin, Seiji Fukumoto, Masahiro Abe, Toshio Matsumoto.
    • Journal Title

      JBMR Plus

      Volume: inpress Issue: 7

    • DOI

      10.1002/jbm4.10182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05327, KAKENHI-PROJECT-17H05104, KAKENHI-PROJECT-17KK0169, KAKENHI-PROJECT-16K11504, KAKENHI-PROJECT-19K21382
  • [Journal Article] Development of versatile non-homologous end joining-based knock-in module for genome editing.2018

    • Author(s)
      Sawatsubashi S, Joko Y, Fukumoto S, Matsumoto T, Sugano SS
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 593-593

    • DOI

      10.1038/s41598-017-18911-9

    • NAID

      120006535030

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327, KAKENHI-PROJECT-16K19556
  • [Journal Article] Recent advances in the management of osteoporosis.2017

    • Author(s)
      Fukumoto S, Matsumoto T
    • Journal Title

      F1000Research

      Volume: 6 Pages: 625-625

    • DOI

      10.12688/f1000research.10682.1

    • NAID

      120006942554

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Journal Article] Assessment criteria for vitamin D deficiency/insufficiency in Japan — proposal by an expert panel supported by Research Program of Intractable Diseases, Ministry of Health, Labour and Welfare, Japan, The Japanese Society for Bone and Mineral Research and The Japan Endocrine Society [Opinion]2017

    • Author(s)
      Okazaki R, Ozono K, Fukumoto S, Inoue D, Yamauchi M, Minagawa M, Michigami T, Takeuchi Y, Matsumoto T, Sugimoto T
    • Journal Title

      Endocr J

      Volume: 64 Issue: 1 Pages: 1-6

    • DOI

      10.1507/endocrj.EJ16-0548

    • NAID

      130005306013

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Journal Article] Serum carboxy-terminal telopeptide of type I collagen levels are associated with carotid atherosclerosis in patients with cardiovascular risk factors2016

    • Author(s)
      Kondo T, Endo I, Aihara K, Onishi Y, Dong B, Ohguro Y, Kurahashi K, Yoshida S, Fujinaka Y, Kuroda A, Matsuhisa M, Fukumoto S, Matsumoto T, Abe M.
    • Journal Title

      Endocr J

      Volume: 63 Issue: 4 Pages: 397-404

    • DOI

      10.1507/endocrj.EJ15-0589

    • NAID

      130005146452

    • ISSN
      0918-8959, 1348-4540
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21201, KAKENHI-PROJECT-25461389, KAKENHI-PROJECT-16H05327
  • [Journal Article] Calcilytic Ameliorates Abnormalities of Mutant Calcium-Sensing Receptor (CaSR) Knock-In Mice Mimicking Autosomal Dominant Hypocalcemia (ADH).2015

    • Author(s)
      Dong B, Endo I, Ohnishi Y, Kondo T, Hasegawa T, Amizuka N, Kiyonari H, Shioi G, Abe M, Fukumoto S, Matsumoto T.
    • Journal Title

      J Bone Miner Res

      Volume: 30 Pages: 1980-1993

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25293215
  • [Journal Article] Evaluation of a new automatedchemiluminescence immunoassay for FGF232012

    • Author(s)
      Shimizu Y, Fukumoto S, Fujita T
    • Journal Title

      J Bone Miner Metab

      Volume: 30 Pages: 217-221

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Anti-FGF23 neutralizing antibodiesameliorate muscle weakness anddecreased spontaneous movement of Hypmice2011

    • Author(s)
      Aono Y, Hasegawa H, Yamazaki Y, ShimadaT, Fujita T, Yamashita T, Fukumoto S
    • Journal Title

      J Bone Miner Res

      Volume: 26 Pages: 803-810

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Apatient with hypophosphatemicrickets and ossification of posteriorlongitudinal ligament caused by anovel homozygous mutation in ENPP1gene2011

    • Author(s)
      Saito T, Shimizu Y, Hori M, Taguchi M, Igarashi T, Fukumoto S, Fujita T
    • Journal Title

      Bone

      Volume: 49 Pages: 913-916

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Fibroblast growth factor 23 as a phosphotropic hormone and beyond2011

    • Author(s)
      Fukumoto S, et al.
    • Journal Title

      J Bone Miner Metab

      Volume: 29 Issue: 5 Pages: 507-514

    • DOI

      10.1007/s00774-011-0298-0

    • NAID

      10030894330

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Direct evidence for a causative role of FGF23 in the abnormal renal phosphatehandling and vitamin D metabolism inrats with early-stage chronic kidneydisease2010

    • Author(s)
      Hasegawa H, Nagano N, Urakawa I, Yamazaki Y, Iijima K, Fujita T, Yamashita T, Fukumoto S, Shimada T
    • Journal Title

      Kidney Int

      Volume: 78 Pages: 975-980

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Familial hypophosphatemicrickets caused by a large deletion inPHEX gene2009

    • Author(s)
      Saito T, Nishii Y, Yasuda T, Ito N, Suzuki H, Igarashi T, Fukumoto S, Fujita T
    • Journal Title

      Eur J Endocrinol

      Volume: 161 Pages: 647-651

    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Therapeutic effect of anti-FGF23 antibodies in hypophosphatemicrickets/osteomalacia2009

    • Author(s)
      Aono Y, Yamazaki Y, Yasutake J, Kawata T, Hasegawa H, Urakawa I, Fujita T, WadaM, Yamashita T, Fukumoto S, Shimada T
    • Journal Title

      J Bone Miner Res

      Volume: 24 Pages: 1879-1888

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Journal Article] Anti-FGF23 neutralizing antibodies demonstrate the physiological role and structural features of FGF232008

    • Author(s)
      Yamazaki Y, Tamada T, Kasai N, Urakawa I, Aono Y, Hasegawa H, Fujita T, Kuroki R, Yamashita T, Fukumoto S, Shimada T
    • Journal Title

      J Bone Miner Res 23

      Pages: 1509-1518

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Clinical usefulness of measurement of fibroblast growth factor 23(FGF23)in hypophosphatemic patients-Proposal of diagnostic criteria using FGF23 measurement-2008

    • Author(s)
      Endo I, Fukumoto S, Ozono K, Namba N, Tanaka H, Inoue D, Minagawa M, Sugimoto T, Yamauchi M, Michigami T, Matsumoto T
    • Journal Title

      Bone 42

      Pages: 1235-1239

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Physiological regulation and disorders of phosphate metabolism-Pivotalrole of fibroblast growth factor 23-2008

    • Author(s)
      Fukumoto S
    • Journal Title

      Intern Med 47

      Pages: 337-343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Actions and mode of actions of FGF19 subfamily members2008

    • Author(s)
      Fukumoto S
    • Journal Title

      Endocr J 55

      Pages: 23-31

    • NAID

      10021264366

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Physiological regulation and disorders of phosphate metabolism-Pivotal role of fibroblast growth factor 23-2008

    • Author(s)
      Fukumoto S
    • Journal Title

      Intern Med 47

      Pages: 337-343

    • NAID

      130000079690

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] FGF23 is a hormone regulating phosphate metabolism-Unique biological characteristics of FGF23-2007

    • Author(s)
      Fukumoto S, et al.
    • Journal Title

      Bone 40(5)

      Pages: 1190-1195

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Fibroblast growth factor (FGF)23 in patients with acromegaly2007

    • Author(s)
      Ito N, Fukumoto S, Taguchi M, Takeshita A, Takeuchi Y, Yamada S, Fujita T
    • Journal Title

      Endocr J 54

      Pages: 481-484

    • NAID

      130004770047

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Hyperostosis-hyperphosphatemia syndrome : A congenital disorder of O-glycosylation associated with augmented processing of fibroblast growth factor 232007

    • Author(s)
      Frishberg Y, Ito N, Rinat C, Yamazaki Y, Feinstein S, Urakawa I, Navon-Elkan P, Becker-Cohen R, Yamashita T, Araya K, Igarashi T, Fujita T, Fukumoto S
    • Journal Title

      J Bone Miner Res 27

      Pages: 235-242

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] FGF23 is a hormone regulating phosphate metabolism-Unique biological characteristics of FGF23-2007

    • Author(s)
      Fukumoto S, Yamashita T
    • Journal Title

      Bone 40

      Pages: 1190-1195

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Effect of acute changes of serum phosphate on fibroblast growth factor (FGF)23 levels in human2007

    • Author(s)
      Ito N, Fukumoto S, Takeuchi Y, Takeda S, Suzuki H, Yamashita T, Fujita T
    • Journal Title

      J Bone Miner Metab 25

      Pages: 419-422

    • NAID

      10024125586

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Fibroblast growth factor-23(FGF23)in patients with transient hypoparathyroidism : Its important role in serum phosphate regulation2007

    • Author(s)
      Yamashita H, Yamazaki Y, Hasegawa H, Yamashita T, Fukumoto S, Shigematsu T, Kazama JJ, Fukagawa M, Noguchi S
    • Journal Title

      Endocr J 54

      Pages: 465-470

    • NAID

      130004770044

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Klotho converts canonical FGF receptor into a specific receptor for FGF232006

    • Author(s)
      Urakawa I, Yamazaki Y, Shimada T, Iijima K, Hasegawa H, Okawa K, Fujita T, Fukumoto S, Yamashita T
    • Journal Title

      Nature 444

      Pages: 770-774

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways.2006

    • Author(s)
      Shinoda Y, Yamaguchi M, Ogata N, Akune T, Kubota N, Yamauchi T, Terauchi Y, Kadowaki T, Takeuchi Y, Fukumoto S, Ikeda T, Hoshi K, Chung UI, Nakamura K, Kawaguchi H
    • Journal Title

      J Cell Biochem 99 (1)

      Pages: 196-208

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590972
  • [Journal Article] Posttranslational modification of fibroblast growth factor (FGF)-232005

    • Author(s)
      Fukumoto S
    • Journal Title

      Ther Apher Dial 9(4)

      Pages: 319-322

    • Data Source
      KAKENHI-PROJECT-15390293
  • [Journal Article] Ghrelin directly regulates bone formation.2005

    • Author(s)
      Fukushima N, Hanada R, Teranishi H, Fukue Y, Tachibana T, Ishikawa H, Takeda S, Takeuchi Y, Fukumoto S, Kangawa K, Nagata K, Kojima M.
    • Journal Title

      J Bone Miner Res 20 (5)

      Pages: 790-798

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590972
  • [Journal Article] A novel mutation in fibroblast growth factor 23 gene as a cause of tumoral calcinosis.2005

    • Author(s)
      Araya K, Fukumoto S, Backenroth R, Takeuchi Y, Nakayama K, Ito N, Yoshii N, Yamazaki Y, Yamashita T, Silver J, Igarashi T, Fujita T.
    • Journal Title

      J Clin Endocrinol Metab 90 (10)

      Pages: 5523-5527

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590972
  • [Journal Article] Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism2004

    • Author(s)
      Shimada T, Kakitani M, Yamazaki Y, Hasegawa H, Takeuchi Y, Fujita T, Fukumoto S, Tomizuka K, Yamashita T
    • Journal Title

      J Clin Invest 113(4)

      Pages: 561-568

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis.2004

    • Author(s)
      Shimada T, Hasegawa H, Yamazaki Y, Muto T, Hino R, Takeuchi Y, Fujita T, Nakahara K, Fukumoto S, Yamashita T
    • Journal Title

      J Bone Miner Res 19(3)

      Pages: 429-435

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] FGF-23 transgenic mice demonstrate hypophosphatemic rickets with reduced expression of sodium phosphate cotransporter type Iia2004

    • Author(s)
      Shimada T, Urakawa I, Yamazaki Y, Hasegawa H, Hino R, Yoneya T, Takeuchi Y, Fujita T, Fukumoto F, Yamashita T
    • Journal Title

      Biochem Biophys Res Commun 314

      Pages: 409-414

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] Venous sampling for fibroblast growth factor-23 confirms preoperative diagnosis of tumor-induced osteomalacia.2004

    • Author(s)
      Takeuchi Y, Suzuki H, Ogura S, Imai R, Yamazaki Y, Yamashita T, Miyamoto Y, Okazaki H, Nakamura K, Nakahara K, Fukumoto S, Fujita T
    • Journal Title

      J Clin Endocrinol Metab 89(8)

      Pages: 3979-3982

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia2003

    • Author(s)
      Fukumoto S, et al.
    • Journal Title

      N Engl J Med 349-5

      Pages: 505-505

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390293
  • [Journal Article] Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia2003

    • Author(s)
      Fukumoto S et al.
    • Journal Title

      N Eng J Med 349(5)

      Pages: 505-505

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390293
  • [Journal Article] Receptor tyrosine kinases inhibit bone morphogenetic protein-Smad responsive promoter activity and osteoblastic differentiation of murine MC3T3-E1 cells.2003

    • Author(s)
      Nakayama K, Tamura Y, Suzawa M, Harada S, Fukumoto S, Kato M, Miyazono K, Rodan GA, Takeuchi Y, Fujita T.
    • Journal Title

      J Bone Miner Res 18(5)

      Pages: 827-835

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] Decreased AP-1 activity and interleukin-11 expression by bone marrow stromal cells may be associated with impaired bone formation in aged mice.2003

    • Author(s)
      Tohjima E, Inoue D, Yamamoto N, Kido S, Ito Y, Kato S, Takeuchi Y, Fukumoto S, Matsumoto T.
    • Journal Title

      J Bone Miner Res 18(8)

      Pages: 1461-1470

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590970
  • [Journal Article] The role of bone in phosphate metabolism

    • Author(s)
      Fukumoto S.
    • Journal Title

      Mol Cell Endocrinol (in press)

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] The role of bone in phosphate metabolism

    • Author(s)
      Fukumoto S
    • Journal Title

      Mol Cell Endocrinol (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Bone as an endocrine organ

    • Author(s)
      Fukumoto S, Martin TJ
    • Journal Title

      Trends Endocrinol Metab (in press)

    • NAID

      10025632854

    • Data Source
      KAKENHI-PROJECT-18390274
  • [Journal Article] Fibroblast growth factor (FGF) 23 in patients with acromegaly.

    • Author(s)
      Ito, N, Fukumoto S, Taguchi M, Takeshita A, Takeuchi Y, Yamada S, Fujita T.
    • Journal Title

      Endocrine J (in press)

    • NAID

      130004770047

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590972
  • [Presentation] FGF Receptor 1c Works as a Phosphate-Sensor to Regulate FGF23 Production2018

    • Author(s)
      Yuichi Takashi, Yuka Kinoshita, Nobuaki Ito, Shun Sawatsubashi, Hidetaka Kosako, Masahiro Abe, Munehide Matsuhisa, Toshio Matsumoto, and Seiji Fukumoto
    • Organizer
      American Society for Bone and Mineral Research, 2018 Annual Meeting, Montreal, Quebec, Canada
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Presentation] Decreased bone strength induced by persistent activation of calcium-sensing receptor.2017

    • Author(s)
      Itsuro Endo, Bingzi Dong, Yukiyo Ohnishi, Takeshi Kondo, Masahiro Hiasa, Jumpei Teramachi, Shinichi Aizawa, Toshio Matsumoto, Masahiro Abe and Seiji Fukumoto.
    • Organizer
      Annual meeting of America Society of Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Presentation] Muscle-Specific Vitamin D Receptor (VDR) Ablation Results in Reduced Grip Power and Altered Gene Expression Pattern in Mice.2017

    • Author(s)
      Maria K Tsoumpra, Itsuro Endo, Shun Sawatsubashi, Yuichi Takashi, Seiji Fukumoto and Toshio Matsumoto.
    • Organizer
      Annual meeting of America Society of Bone and Mineral Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Presentation] The regulatory mechanisms of FGF23 activity via GALNT3 by phosphate2016

    • Author(s)
      Yuichi Takashi, Yuka Kinoshita, Nobuaki Ito, Maria K Tsoumpra, Shun Sawatsubashi, Toshio Matsumoto, Seiji Fukumoto.
    • Organizer
      Amer Soc Bone Miner Res 2016 Annual Meeting
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2016-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Presentation] FGF23 enhances CYP24A1 transcription in Klotho-dependent way via ERK pathway2016

    • Author(s)
      Maria K Tsoumpra, Shun Sawatsubashi, Yuichi Takashi, Toshio Matsumoto and Seiji Fukumoto.
    • Organizer
      Amer Soc Bone Miner Res 2016 Annual Meeting
    • Place of Presentation
      Atlanta, USA
    • Year and Date
      2016-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05327
  • [Presentation] リンの骨芽細胞に及ぼす影響2012

    • Author(s)
      岡本剛明、田口学、福本誠二、藤田敏郎
    • Organizer
      第30回日本骨代謝学会学術集会
    • Place of Presentation
      京王プラザホテル
    • Year and Date
      2012-07-20
    • Data Source
      KAKENHI-PROJECT-22591007
  • [Presentation] Hypophosphatemia and FGF232011

    • Author(s)
      Fukumoto S
    • Organizer
      IOF Regionals-ANZBMS Annual Scientific Meeting with JSBMR
    • Place of Presentation
      Gold Coast, Australia(招待講演)
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] Hypophosphatemia and FGF232011

    • Author(s)
      Fukumoto S
    • Organizer
      International Osteoporosis Foundation Regionals-Australia & New Zealand Bone & Mineral Society Annual Scientific Meeting with Japanese Society for Boneand Mineral Research
    • Place of Presentation
      Gold Coast, Australia
    • Year and Date
      2011-09-07
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] Evaluation of a new automatedchemiluminescence immunoassay of FGF232011

    • Author(s)
      Shimizu Y, Fukumoto S, Fujita T
    • Organizer
      33rd Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-09-19
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] Significance of measurement of FGF23 inthe management of patients withtumor-induced osteomalacia(TIO)2010

    • Author(s)
      Shimizu Y, Ito N, Suzuki H, Okamoto T, Hori M, Fukumoto S, Fujita T
    • Organizer
      International Congress of Endocrinology 2010
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-03-30
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] FGF23 and disorders ofphosphate metabolism2010

    • Author(s)
      Fukumoto S
    • Organizer
      9th National Congress of Endocrinology Bulgarian Society of Endocrinology
    • Place of Presentation
      Provdiv, Bulgaria
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] FGF23 and disorders of phosphate metabolism2010

    • Author(s)
      Fukumoto S
    • Organizer
      9^<th> National Congress of Endocrinology Bulgarian Society of Endocrinology
    • Place of Presentation
      Plovdiv, Bulgaria
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] Regulation of bone andmineral metabolism by bone-derived hormone2009

    • Author(s)
      Fukumoto S
    • Organizer
      31st Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Denver, USA
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] FGF23 and disorders ofphosphate metabolism2009

    • Author(s)
      Fukumoto S
    • Organizer
      31st Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Denver, USA
    • Year and Date
      2009-09-13
    • Data Source
      KAKENHI-PROJECT-21390284
  • [Presentation] Rare cases of X-linked hypophosphatemic rickets/osteomalacia mimicking autosomal recessive hypophosphatemic rickets/osteomalacia2008

    • Author(s)
      Saito T, Suzuki H, Ito N, Igarashi T, Fukumoto S, Fujita T
    • Organizer
      Thirtieth Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Montreal
    • Year and Date
      2008-09-12
    • Data Source
      KAKENHI-PROJECT-18390274
  • [Presentation] Analysis and importance of glycosylation status in FGF23 protein2007

    • Author(s)
      Suzuki H, Fukumoto S, Ito N, Fujita T
    • Place of Presentation
      Honolulu
    • Year and Date
      2007-09-19
    • Data Source
      KAKENHI-PROJECT-18390274
  • [Presentation] O-Linked Glycosylation by ppGaNTase-T3 Prevents Processing of Fibroblast Growth Factor (FGF)232006

    • Author(s)
      Ito N, Fukumoto S, Yamashita T, Frishberg Y, Fujita T
    • Organizer
      Twenty-Eighth Annual Meeting of the American Society for Bone and Mineral Research
    • Place of Presentation
      Philadelphia
    • Year and Date
      2006-09-16
    • Data Source
      KAKENHI-PROJECT-18390274
  • [Presentation] Effect of a calcilytic compound in autosomal dominant hypocalcemia model mice.

    • Author(s)
      Bingzi Dong, Itsuro Endo, Takeshi Kondo, Yukiyo Ohnishi, Masahiro Abe, Seiji Fukumoto, Tomoka Hasegawa, Norio Amizuka, Shin-ichi Aizawa, Toshio Matsumoto
    • Organizer
      American Society of Bone and Mineral Research
    • Place of Presentation
      Houston (USA)
    • Year and Date
      2014-09-12 – 2014-09-15
    • Data Source
      KAKENHI-PROJECT-25293215
  • 1.  TAKEUCHI Yasuhiro (50202164)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 10 results
  • 2.  NAKAYAMA Konosuke (20322076)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  MATSUMOTO Toshio (20157374)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 10 results
  • 4.  TAGUCHI Manabu (00265141)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 5.  沢津橋 俊 (70535103)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 6.  TAKESHITA Akira (20322646)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  ABE Masahiro (80263812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  遠藤 逸朗 (10432759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  粟飯原 賢一 (70372711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MARIA TSOUMPRA (80756198)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 11.  高士 祐一 (50803524)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  TAKAHASHI Kazuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  滝川 浩郷
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  川浪 大治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  安部 正博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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