Yamanaka Hiroyasu 山中浩泰

… Alternative Names

山中浩泰ヤマナカヒロヤス

YAMANAKA Hiroyasu 山中浩泰

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Researcher Number	30202386
Other IDs
External Links
Affiliation (Current)	2025: 広島国際大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2025: 広島国際大学, 薬学部, 教授 2022 – 2023: 広島国際大学, 薬学部, 教授 2016 – 2018: 広島国際大学, 薬学部, 教授 2005 – 2007: Hiroshima International University, Faculty of Pharmaceutical Sciences, Professor, 薬学部, 教授 1997 – 2004: 徳島文理大学, 薬学部, 助教授 … More 1993 – 1996: 徳島文理大学, 薬学部, 講師 1994: 徳島文理大学, 講師 1991 – 1992: 徳島文理大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Basic Section 58010:Medical management and medical sociology-related Except Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / 細菌学 / Basic Section 58010:Medical management and medical sociology-related / Medical and hospital managemen / Biological pharmacy
Keywords	Principal Investigator 大腸菌 / 耐熱性エンテロトキシン / 分泌機構 / TolC / プロセシング / 外膜通過 / ジスルフィド結合 / 成熟化 / ジスルフィド結合形成 / 膜通過 … More / プロセッシング / 膜透過 / 耐熱性下痢原因毒素 / 院内感染制御 / 抗菌薬使用数量 / 分子疫学 / 薬剤耐性菌 / Processing / Drug efflux / Outer membrane transport / Heat-stable enterotoxin / Escherichia coli / 薬剤排出 / プロ領域 … More Except Principal Investigator 大腸菌 / 毒素 / 下痢 / 遺伝子操作 / Escherichia coli / Enterotoxin / 膜 / 分泌 / プロテアーゼ / Aeromonas / 成熟化 / エンテロトキシン / 立体構造 / ジスルフィド結合 / 分子疫学 / 薬剤耐性菌 / 院内感染管理 / 薬剤耐性 / Protease / 溶血毒素 / アエロモナス / Alkyl gallate / EGFR / Gefitinib / p21WAF1 / GADD153 / Sulindac / EGCG / 溶血毒 / Maturation / Secretion / 膜タンパク質 / 細胞膜 / アエロモナス菌 / Diarrhea / 成熟 / ELISA / 抗菌薬使用数量 / バンコマイシン耐性腸球菌 / メチシリン耐性黄色ブドウ球菌 / 抗菌薬 / 院内感染制御 / 病院・医療管理学 / Hemolvsin / Maturation pathway / Bacterial toxin / Enteric infection / カルボキシ末端 / メタロプロテアーゼ / セリンプロテアーゼ / 下痢毒素 / 成熟化過程 / 細菌毒素 / 腸管感染症 / Pathogenicity / Secretion apparatus / Chaperone / Bacteria / 外膜蛋白質 / タンパク毒素 / 基質 / フーリン / 病原性 / 分泌装置 / シャペロン / 細菌 / Apoptosis / 5-FU / PC-9 / 相乗効果 / GA153DD / sulindac / Alkyl gallete / アポトーシス / Hemolysin / Membrane protein / Aeromonas spp. / グラム陰性菌 / 菌体外毒素 / 蛋白分解酵素 / Membrane Protein / Cytoplasmic Membrane / 遺伝子 / 菌対外毒素 / 耐熱性下痢毒素 / 膜タンパク / Gene manipulation / Disulfide bond / Membrane / Toxin / ジスルフィド精合 / レセプター / プロスタグランディン / プロスタグランジン / 化学修飾 / 不痢原因毒素 / 膜透過 / シグナルペプタイド / 前駆体 / 下痢原因毒素 Less

Developing Novel Antimicrobial Stewardship Programs Based on Molecular Epidemiology of Drug-Resistant Bacteria and Antibiotic Utilization AnalysisPrincipal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Hiroshima International University
地域圏における抗菌薬使用数量や薬剤耐性菌の疫学解析が抗菌薬適正使用に与える影響
- Principal Investigator
  
  佐和章弘
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58010:Medical management and medical sociology-related
- Research Institution
  Hiroshima International University
Molecular epidemiological analysis for methicillin-resistant Staphylococcus aureus (MRSA) isolated in the hospitals in Kure District, Hiroshima
- Principal Investigator
  
  Sawa Akihiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical and hospital managemen
- Research Institution
  Hiroshima International University
Analysis of Maturation pathway protein toxin of Enteric Bacteria and Studies of Prevention of Diarrhea
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Okayama University
Analysis of secretion and maturation pathway of bacterial proteintoxin and its application to clinical study
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKAYAMA UNIVERSITY
Studies on proteins involved in synergistic up-regulation of apoptosis-related genes
- Principal Investigator
  
  FUJIKI Hirota
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokushima Bunri University, Faculty of Pharmaceutical Sciences, Laboratory of Biochemistry
Studies on the secretion and maturation pathway of bacterial exotoxin
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKAYAMA UNIVERSITY
Functional Studies of Escherichia coli Outer Membrane Protein TolCPrincipal Investigator
- Principal Investigator
  
  YAMANAKA Hiroyasu
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIの外膜通過過程の解析Principal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
Studies on the Processes of Construction of Active Structure of Bacterial Enterotoxin and of the Secretion to Milieu
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  OKAYAMA UNIVERSITY
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIの外膜通過機構Principal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
Analysis of Maturation Pathway of Heat-Stable Enterotoxin of Escherichia coli
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIIの活性発現機序の解析
- Principal Investigator
  
  岡本敬の介
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIの外膜通過機構の解析Principal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIIのジスルフィド結合の形成とレセプターの解析
- Principal Investigator
  
  岡本敬の介
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性エンテロトキシンIの外膜通過機構Principal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素のジスルフィド結合形成の分子論的研究
- Principal Investigator
  
  岡本敬の介
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素Iの分泌とプロセッシングPrincipal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素IIの構造と作用機序に関する研究
- Principal Investigator
  
  岡本敬の介
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素Iのプロ領域の機能と構成アミノ酸Principal Investigator
- Principal Investigator
  
  山中浩泰
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素IIの活性と構造に関する研究
- Principal Investigator
  
  岡本敬の介
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Tokushima Bunri University
大腸菌耐熱性下痢原因毒素の分泌機序の分子論的研究
- Principal Investigator
  
  OKAMOTO Keinosuke
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Tokushima Bunri University

All 2024 2023 2022 2019 2007 2006 2005 2004 2003 2002

All Journal Article Presentation

[Journal Article] Molecular epidemiological and pharmaceutical studies of methicillin-resistant Staphylococcus aureus isolated at hospitals in Kure City, Japan2022
- Author(s)
  Maeda Ryuto、Kobayashi Hidetomo、Higashidani Mami、Matsuhisa Tetsuaki、Sawa Akihiro、Miyake Katsushi、Tayama Yoshitaka、Kimura Kouji、Itoh Hiroyuki、Okano Taichi、Seike Soshi、Yamanaka Hiroyasu
- Journal Title
  
  Access Microbiology
  
  Volume: 4 Issue: 2 Pages: 000319-000319
- DOI
  10.1099/acmi.0.000319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16255, KAKENHI-PROJECT-20K07504, KAKENHI-PROJECT-22K10431
[Journal Article] Studies on the region involved in the transport activity of Escherichia coli TolC by chemeric protein analysis2007
- Author(s)
  Hiroyasu Yamanaka,
- Journal Title
  
  Microbial Pathogenesis 42
  
  Pages: 184-192
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590423
[Journal Article] Studies on the region involved in the transport activity of Eshcrichia coli TolC by chemeric protein analysis2007
- Author(s)
  Hiroyasu, Yamanaka, Satoshi, Tadokoro, Masaya, Miyano, Eizo, Takahashi, Hidetomo, Kobayashi, Keinosuke, Okamoto
- Journal Title
  
  Microbial Pathogenesis 42
  
  Pages: 184-192
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590423
[Journal Article] Studies on the region involved in the transport activity of Eshcrichia coli TolC by chemeric protein analysis2007
- Author(s)
  Hiroyasu Yamanaka
- Journal Title
  
  Microbial Pathogenesis 42
  
  Pages: 184-192
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590423
[Journal Article] Cleavage specificity of the serine protease of Aeromonas sobria, a member of the kexin family of subtilases2006
- Author(s)
  Hidetomo, Kobayashi, Eizo, Takahashi, Keiji, Oguma, Yoshio, Fujii, Hiroyasu, Yamanaka, Tomoe, Negishi, Sakae, Arimoto-Kobayashi, Takao, Tsuji, Keinosuke, Okamoto
- Journal Title
  
  FEMS Microbiology Letters 256(1)
  
  Pages: 165-170
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590423
[Journal Article] タバコタール耐性の口腔内細菌Staphylococcus aureusと発癌性2005
- Author(s)
  山中浩泰他
- Journal Title
  
  THE LUNG perspectives 13・1
  
  Pages: 62-65
- Data Source
  KAKENHI-PROJECT-15590085
[Journal Article] タバコタール耐性の口腔内細菌Staphylococcus aureusの発癌性2005
- Author(s)
  山中浩泰 et al.
- Journal Title
  
  The Lung perspectives 13
  
  Pages: 62-65
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590085
[Journal Article] タバコタール耐性の口腔内細菌Staphylococcus aureusの発癌性2005
- Author(s)
  山中浩泰他
- Journal Title
  
  The Lung perspectives 13
  
  Pages: 62-65
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590085
[Journal Article] Amino acid residues involved in the expression of the activity of Escherichia coli TolC2004
- Author(s)
  Hiroyasu Yamanaka 他
- Journal Title
  
  Microbiology and Immunology 48(10)
  
  Pages: 713-722
- NAID
  10013604757
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590360
[Journal Article] Amino acid residues involved in the expression of the activity of Escherichia coli TolC.2004
- Author(s)
  Hiroyasu Yamanaka, Naoyuki Morisada, Masaya Miyano, Hideaki Tsuge, Sumio Shinoda, Eizo Takahashi, Keinosuke Okamoto
- Journal Title
  
  Microbiology and Immunology 48(10)
  
  Pages: 713-722
- NAID
  10013604757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590360
[Journal Article] Amino acid residues involved in the expression of the activity of Escherichia coli TolC2004
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Microbiology and Immunology 48・10
  
  Pages: 713-722
- NAID
  10013604757
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Amino acid residues involved in the expression of the activity of Escherichia coli TolC2004
- Author(s)
  山中浩泰
- Journal Title
  
  Microbiology and Immunology 48・10
  
  Pages: 713-722
- NAID
  10013604757
- Data Source
  KAKENHI-PROJECT-16590360
[Journal Article] Amino acid residues involved in the expression of the Activity of Escherichia coli TolC2004
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Microbiology and Immunology Vol.48
  
  Pages: 713-722
- NAID
  10013604757
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Amino acid residues involved in the expression of the activity of Eccherichia coli TolC2004
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Microbiology and Immunology 48
  
  Pages: 713-722
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Delivery of heat-stable enterotoxin of Escherichia coli to the exterior and the action of the toxin to induce diarrhea2003
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Recent Research Developments in Infection & Immunity Vol.1
  
  Pages: 45-59
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Maturation and secretory pathway of heat-stable enterotoxin of enterotoxigenic Escherichia coli2003
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Advancement of Life Science Vol.1
  
  Pages: 107-118
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Site-directed mutagenesis studies of the amino acid residue at position 412 of Escherichia coli TolC which is required for the activity2002
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Microbial Pathogenesis 33
  
  Pages: 81-89
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Journal Article] Site-directed mutagenesis studies of the amino acid residue at position 412 of Escherichia coli TolC which is required for the activity2002
- Author(s)
  Hiroyasu Yamanaka et al.
- Journal Title
  
  Microbial Pathogenesis Vol.33
  
  Pages: 81-89
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570252
[Presentation] 呉市医療施設から分離されたメチシリン耐性黄色ブドウ球菌の遺伝子型の特定と抗菌薬管理に基づく感染制御2024
- Author(s)
  川崎太雅、小林秀丈、前田龍人、能美伸太郎、佐々木彩、日浦和徳、堀田尚克、岡野太一、伊藤博之、木村幸司、清家総史、佐和章弘、山中浩泰
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K10431
[Presentation] 広島県呉市の医療機関における薬剤耐性菌の調査と感染制御に向けた取り組み2023
- Author(s)
  小林秀丈、前田龍人、東谷麻未、能美伸太郎、佐々木彩、日浦和徳、堀田尚克、岡野太一、伊藤博之、木村幸司、清家総史、佐和章弘、山中浩泰
- Organizer
  第35回微生物シンポジウム
- Data Source
  KAKENHI-PROJECT-22K10431
[Presentation] 呉地区の医療施設で分離されたメチシリン耐性黄色ブドウ球菌（MRSA）の分子疫学解析2019
- Author(s)
  前田龍人、小林秀丈、吉崎瑞穂、佐和章弘、岡野太一、木村幸司、清家総史、山中浩泰
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K09194
[Presentation] 大腸菌耐熱性エンテロトキシン(ST)の菌体外分泌過程の解析2007
- Author(s)
  山中浩泰
- Organizer
  第60回日本細菌学会中国・四国支部総会
- Place of Presentation
  岡山県総社市
- Data Source
  KAKENHI-PROJECT-18590423

1. OKAMOTO Keinosuke (70131183)

# of Collaborated Projects: 12 results

# of Collaborated Products: 3 results
2. FUJII Yoshio (60122587)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
3. 木村幸司 (90389106)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. 小林秀丈 (70441574)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. NOMURA Tomohiko (00289315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. NAKAO Hiroshi (20237217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Sawa Akihiro (70389104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 清家総史 (90806275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. SHINODA Sumio (50029782)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KOBAYASHI Sagae (90212654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NEGISHI Tomoe (80116491)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUJIKI Hirota (60124426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KUZUHARA Takashi (00260513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SUENAGA Midori (00389181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MIYOSHI Shin-ichi (60182060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TAKAHASHI Eizo (70379733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 竹治美穂 (20320103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Yamanaka Hiroyasu 山中 浩泰

山中 浩泰 ヤマナカ ヒロヤス

YAMANAKA Hiroyasu 山中 浩泰

Research Projects

Research Products

Co-Researchers

Developing Novel Antimicrobial Stewardship Programs Based on Molecular Epidemiology of Drug-Resistant Bacteria and Antibiotic Utilization AnalysisPrincipal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Functional Studies of Escherichia coli Outer Membrane Protein TolCPrincipal Investigator

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大腸菌耐熱性エンテロトキシンIの外膜通過過程の解析Principal Investigator

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大腸菌耐熱性エンテロトキシンIの外膜通過機構Principal Investigator

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大腸菌耐熱性エンテロトキシンIの外膜通過機構の解析Principal Investigator

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Yamanaka Hiroyasu 山中浩泰

山中浩泰ヤマナカヒロヤス

YAMANAKA Hiroyasu 山中浩泰