AOYAGI Sakae 青柳榮

… Alternative Names

青柳栄アオヤギサカエ

青柳榮アオヤギサカエ

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Researcher Number	30212385
Other IDs
Affiliation (based on the past Project Information) *help	2010 – 2012: 東京薬科大学, 薬学部, 教授 2007: Tokyo University of Pharmacy and Life Science, 薬学部, 准教授 1994 – 2006: 東京薬科大学, 薬学部, 助教授 2003: Tokyo University of Pharmacy and Life Science, Department of Pharmacy, Associate Professor
Review Section/Research Field	Principal Investigator Chemical pharmacy / Chemical pharmacy Except Principal Investigator Chemical pharmacy / Science and Engineering
Keywords	Principal Investigator acylnitroso compounds / marine alkaloids / アシルニトロソ化合物 / 海洋アルカロイド / pinnaic acid / halichlorine / ピンナ酸 / ハリクロリン / formal total synthesis / ring-closing metathesis … More / intramolecular ene reaction / アザスピロ[4.5]デカン / 形式全合成 / オレフィン閉環メタセシス / 分子内エン反応 / ene reaction / ピンナ酸類 / エン反応 / intramolecular hetero-Diels-Alder reaction / lepadiformin / fasicularin / antitumor agent / tunicate / 分子内ヘテロDiels一Alder反応 / レパジホルミン訂正式 / 分子内ヘテロDiels-Alder反応 / レパジホルミン / ファシクラリン / 抗腫瘍性 / ホヤ / 天然物合成 / 天然物合成化学 / 合成化学 … More Except Principal Investigator 不斉合成 / ヤドクガエルアルカロイド / エピバチジン / エナンチオ選択的合成 / photodimerization / Heck reaction / three-component coupling / monoterpene alkaloids / incavilline C / incarvilateine / analgestic agent / non-opioid / Intramolecular Heck Reaction / Three-Component Coupling / Total Syntheis / Antinociceptive Activity / Monoterpene Alkaloid / Incarvine C / Incarvillateine / モノテルペンアルカロイド / 光二量化反応 / Heck反応 / 3成分連結法 / モノルペンアルカロイド / インカビリンC / インカビラテイン / 鎮痛物質 / 非オピオイド性 / binding affinity / nicotinic acetylcholine receptor / internitrogen distance / oxaspirocyclic analogues / non-opioidal analgesic agent / epibatidine / Dendrobatid alkaloid / ヘテロディールス-アルダー反応 / スピロ化合物 / 非麻薬性鎮痛薬 / 配座固定アナログ / 結合親和性 / ニコチン性アセチルコリン受容体 / 窒素原子間距離 / オキサスピロアナログ / 非オピオイド性鎮痛薬 / palladium-catalyzed carbonylation / exocyclic alkenyl group / asymmetric synthesis / pumiliotoxin 225F / pumiliotoxin A / poison-dart alkaloids / プミリオトキシン 229F / パラジウム触媒カルボニル化反応 / 環外アルケニル基 / プミリオトキシン225F / プミリオトキシンA / intramolecular hetero Diels-Alder reaction / chiral acylnitroso compound / chiral hydroxamic acid / cytotoxicity against human cancer cell lines / decahydroquinoline / tunicate / marine alkaloids / lepadins A,B,C / 不斉反応 / π-スタッキング相互作用 / ヘテロDiels-Alder反応 / 8-ナフチルメントール / アシルニトロソ化合物 / 非オピオイド性鎮痛作用 / 矢毒蛙アルカロイド / 分子内ヘテロディールズ・アルダー反応 / 分子内へテロディールズ・アルダー反応 / キラルアシルニトロソ化合物 / キラルヒドロキサム酸 / ヒト腫瘍細胞増殖抑制活性 / デカヒドロキノリン / 群体ホヤ / 海産アルカロイド / レパジンA,B,C / ベンゾビシクロ[3.2.1]オクタン / 分子内Friedel-Crafts反応 / セファロサイクリジンA / ハイイヌガヤ / アズレノ[5,6-b]フラノン / エンインメタセシス / [3.3]シグマトロピー転位 / ヘデラシンB / ヘデラシンA / カキドオシ / オクタヒドロアズレノ[5.6-b]フラノン / ヘデラシンA及びB / 抗腫瘍性アルカロイド / セイヨウカキドオシ / アザビシクロ[3.3.1]ノナン / N.O-アセタール化 / マダンガミンA / 抗生物質 / 鉄カルボニル錯体 / 環化異性化反応 / 酢酸パラジウム(II) / (+)-ストレプタゾリン / 分子内環化反応 / アロプミリオトキシン / アルケニルクロム化合物 Less

Synthetic Studies on Structurally Novel Antitumor Natural Products, HederacinesPrincipal Investigator
- Principal Investigator
  
  AOYAGI Sakae
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
多環式含窒素分子骨格構築法の開発と生体機能アルカロイドの合成Principal Investigator
- Principal Investigator
  
  青柳榮, 樹林千尋
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo University of Pharmacy and Life Science
Synthesis of bioactive marine natural products using intramolecular ene reaction of acylnitroso compoundsPrincipal Investigator
- Principal Investigator
  
  AOYAGI Sakae
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
Asymmetric synthesis of a novel antinociceptive substance, incarvillateine
- Principal Investigator
  
  KIBAYASHI Chihiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Synthetic Studies of Bioactive Marine Alkaloids Based on Nitroso-Ene ReactionPrincipal Investigator
- Principal Investigator
  
  AOYAGI Sakae
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy & Life Science
Synthesis of Conformationally Constrained Analogues of Epibatidine and Development of Non-opioidal Analgesics
- Principal Investigator
  
  KIBAYASHI Chihiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Stereocontrolled synthesis of antitumor alkaloids based on intramolecular hetero-Diels-Alder reaction of acylnitroso compoundsPrincipal Investigator
- Principal Investigator
  
  AOYAGI Sakae
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy & Life Science
Asymmetric Synthesis of Poison-Dart Alkaloids Pumiliotoxins
- Principal Investigator
  
  KIBAYASHI Chihiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy & Life Science
Chiral Synthesis of New Biologically Active Alkaloids Utilizing Hetero Diels-Alder Reaction
- Principal Investigator
  
  KIBAYASHI Chihiro
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy & Life Science
エンイン化合物のpd(II)環化異性化反応を用いる(+)-ストレプタゾリンの全合成
- Principal Investigator
  
  樹林千尋
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
アルケニルクロム化合物の分子内環化反応を用いるアロプミリオトキシンの不斉合成
- Principal Investigator
  
  KIBAYASHI Chihiro
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science

All 2011 2007 2006 2004 2003

All Journal Article Presentation

[Journal Article] Toward the Racemic Total Synthesis of Hederacines A and B : Construction of an Advanced Tricyclic Intermediate2011
- Author(s)
  Miho Yamashita, Tetsuya Yamashita, Sakae Aoyagi
- Journal Title
  
  Organic Letters
  
  Volume: 13 Pages: 2204-2207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590020
[Journal Article] Synthesis of the eleven-membered ring of the marine alkaloids, madangamines2006
- Author(s)
  Y.Yoshimura, J.Inoue, N.Yamazaki, S.Aoyagi, C.Kibayashi
- Journal Title
  
  Tetrahedron Lett. 47・20
  
  Pages: 3489-3489
- Data Source
  KAKENHI-PROJECT-16073218
[Journal Article] A Formal Total Synthesis of(±)-Halichlorine Cid and (±)-Pinnaic Acid2004
- Author(s)
  Yosuke Matsumura, Sakae Aoyagi, Chihiro Kibayashi
- Journal Title
  
  Org. Lett. 6(6)
  
  Pages: 965-968
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590024
[Journal Article] A Formal Total Synthesis of (±)-Halichlorine and (±)-Pinnaic Acid2004
- Author(s)
  Yosuke Matsumura, Sakae Aoyagi, Chihiro Kibayashi
- Journal Title
  
  Org.Lett. 6(6)
  
  Pages: 965-968
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590024
[Journal Article] Efficient Synthesis of the Azaspirocycle Core Structure of Halichlorine and Pinnaic Acid by Intramolecular Acylnitroso Ene Reaction2003
- Author(s)
  Yosuke Matsumura, Sakae Aoyagi, Chihiro Kibayashi
- Journal Title
  
  Org.Lett. 5(18)
  
  Pages: 3249-3252
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590024
[Journal Article] Efficient Synthesis of the Azaspirocycle Core Structure of Halichlorine and Pinnaic Acid by Intramolecular Acylnitroso Ene Reaction2003
- Author(s)
  Yosuke Matsumura, Sakae Aoyagi, Chihiro Kibayashi
- Journal Title
  
  Org. Lett. 5(18)
  
  Pages: 3249-3252
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590024
[Presentation] (±)-ヘデラシンA及びBの全合成研究2007
- Author(s)
  青柳栄
- Organizer
  第33回反応と合成の進歩シンポジウム
- Place of Presentation
  長崎
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-16073218

1. KIBAYASHI Chihiro (80057330)

# of Collaborated Projects: 7 results

# of Collaborated Products: 1 results
2. YAMAZAKI Naoki (30277264)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. ABE Hideki (00328551)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results

AOYAGI Sakae 青柳 榮

青柳 栄 アオヤギ サカエ

青柳 榮 アオヤギ サカエ

Research Projects

Research Products

Co-Researchers

Synthetic Studies on Structurally Novel Antitumor Natural Products, HederacinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多環式含窒素分子骨格構築法の開発と生体機能アルカロイドの合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Synthesis of bioactive marine natural products using intramolecular ene reaction of acylnitroso compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Asymmetric synthesis of a novel antinociceptive substance, incarvillateine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthetic Studies of Bioactive Marine Alkaloids Based on Nitroso-Ene ReactionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of Conformationally Constrained Analogues of Epibatidine and Development of Non-opioidal Analgesics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Stereocontrolled synthesis of antitumor alkaloids based on intramolecular hetero-Diels-Alder reaction of acylnitroso compoundsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Asymmetric Synthesis of Poison-Dart Alkaloids Pumiliotoxins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chiral Synthesis of New Biologically Active Alkaloids Utilizing Hetero Diels-Alder Reaction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エンイン化合物のpd(II)環化異性化反応を用いる(+)-ストレプタゾリンの全合成

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アルケニルクロム化合物の分子内環化反応を用いるアロプミリオトキシンの不斉合成

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Toward the Racemic Total Synthesis of Hederacines A and B : Construction of an Advanced Tricyclic Intermediate2011

Author(s)

Journal Title

Data Source

[Journal Article] Synthesis of the eleven-membered ring of the marine alkaloids, madangamines2006

Author(s)

Journal Title

Data Source

AOYAGI Sakae 青柳榮

青柳栄アオヤギサカエ

青柳榮アオヤギサカエ