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HOSODA Fumie  細田 文恵

ORCIDConnect your ORCID iD *help
Researcher Number 30219191
Other IDs
Affiliation (based on the past Project Information) *help 2015: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
2011 – 2014: 独立行政法人国立がん研究センター, 研究所, ユニット長
2010: 独立行政法人国立がん研究センター, 研究所がんゲノミクス研究分野, ユニット長
Review Section/Research Field
Principal Investigator
Medical genome science / Medical genome science
Keywords
Principal Investigator
癌の個性診断 / 分子標的治療 / 発現異常 / 治療標的分子 / 融合遺伝子 / トランスクリプトーム / 胃癌 / ゲノム構造異常解析 / 遺伝子変異 / 個別化医療 / エクソンシークエンス / リンパ節転移 / 乳癌
  • Research Projects

    (2 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (11 People)
  •  Identification of novel fusion genes in gastric cancer by whole transcriptome sequencing: Discovery of potential therapeutic targets for gastric cancerPrincipal Investigator

    • Principal Investigator
      Hosoda Fumie
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      National Cancer Center Japan
  •  Studies on cancer genomics to develop personalized therapy and medicine in breast cancer: Whole exome sequencing analysis of primary breast cancer and its metastatic tumor.Principal Investigator

    • Principal Investigator
      HOSODA Fumie
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      National Cancer Center Japan

All 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

  • [Journal Article] Heat Shock Protein 90 Is a Potential Therapeutic Target in Cholangiocarcinoma.2015

    • Author(s)
      Shirota T, Ojima H, Hiraoka N, Shimada K, Rokutan H, Arai Y, Kanai Y, Miyagawa S, Shibata T.
    • Journal Title

      Mol Cancer Ther.

      Volume: 14 Issue: 9 Pages: 1985-93

    • DOI

      10.1038/ng.3375

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460501, KAKENHI-PROJECT-26461040, KAKENHI-PROJECT-25290074
  • [Journal Article] Integrated genomic and functional analyses reveal glyoxalase I as a novel metabolic oncogene in human gastric cancer.2014

    • Author(s)
      Hosoda F, Inazawa J, et al.
    • Journal Title

      Oncogene.

      Volume: in press Issue: 9 Pages: 1196-206

    • DOI

      10.1038/onc.2014.57

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22134002, KAKENHI-PROJECT-23390325, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-25290074, KAKENHI-PROJECT-25560368, KAKENHI-PROJECT-25640062, KAKENHI-PROJECT-26293304, KAKENHI-PLANNED-15H05908
  • [Journal Article] Mouse Model for ROS1-Rearranged Lung Cancer.2013

    • Author(s)
      Arai Y, Totoki Y, Takahashi H, Nakamura H, Hama N, Kohno T, Tsuta K, Yoshida A, Asamura H, Mutoh M, Hosoda F, Tsuda H, Shibata T
    • Journal Title

      PLoS One

      Volume: 8(2) Issue: 2 Pages: e56010-e56010

    • DOI

      10.1371/journal.pone.0056010

    • Data Source
      KAKENHI-PROJECT-22310123
  • [Journal Article] Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators.2012

    • Author(s)
      Fujimoto A, Totoki Y, Abe T, Boroevich KA, Hosoda F, Nguyen HH, Aoki M, Hosono N, Kubo M, Miya F, Arai Y, Takahashi H, Shirakihara T, Nagasaki M, Shibuya T, Nakano K, Watanabe-Makino K, Tanaka H, Nakamura H, Kusuda J, Ojima H, Shimada K, Okusaka T, Ueno M, Shigekawa Y, Kawakami Y, Arihiro K, Ohdan H, Gotoh K, Ishikawa O, Ariizumi S, Yamamoto M, Yamada T, Chayama K, Kosuge T, Yamaue H, Kamatani N, Miyano S, Nakagama H, Nakamura Y, Tsunoda T, Shibata T, Nakagawa H
    • Journal Title

      Nature Genetic

      Volume: 44 Issue: 7 Pages: 760-764

    • DOI

      10.1038/ng.2291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310123, KAKENHI-PROJECT-24659368, KAKENHI-PLANNED-22116010, KAKENHI-PLANNED-22134004, KAKENHI-PLANNED-22134008
  • [Journal Article] High-resolution characterization of a hepatocellular carcinoma genome2011

    • Author(s)
      Totoki Y, Tatsuno K, Yamamoto S, Arai Y, Hosoda F, Ishikawa S, Tsutsumi S,Sonoda K, Totsuka H, Shirakihara T,Sakamoto H, Wang L, Ojima H, Shimada K, Kosuge T, Okusaka T, Kato K, Kusuda J, Yoshida T, Aburatani H & S h i b a t a T
    • Journal Title

      Nat Genet

      Volume: 43(5) Issue: 5 Pages: 464-9

    • DOI

      10.1038/ng.804

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-22310123
  • [Journal Article] DEK oncoprotein regulates transcriptional modifiers and sustains tumor initiation activity in high-grade neuroendocrine carcinoma of the lung.2010

    • Author(s)
      Shibata T, Kokubu A, Miyamoto M, Hosoda F, Gotoh M, Tsuta K, Asamura H, Matsuno Y, Kondo T, Imoto I, Inazawa J, Hirohashi S
    • Journal Title

      Oncogene

      Volume: 29 Pages: 4671-4681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Patent] FUSION GENE OF CEP55 GENE AND RET GENE2015

    • Inventor(s)
      Tatsuhiro Shibata, Fumie Hosoda
    • Industrial Property Rights Holder
      国立がん研究センター
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-01-26
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25290074
  • [Patent] 胃がんの責任因子としての新規融合遺伝子2013

    • Inventor(s)
      柴田龍弘、細田文恵
    • Industrial Property Rights Holder
      国立がん研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2013-263032
    • Filing Date
      2013-12-19
    • Data Source
      KAKENHI-PROJECT-25290074
  • [Presentation] Identification of novel fusion genes in 218 gastric primary cancers by paired-end RNA sequencing.2015

    • Author(s)
      Hosoda F, Totoki Y, Rokutan H, Hama N, Arai Y, Taniguchi H, Shibata T.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋市 名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25290074
  • [Presentation] High-throughput sequencing analysis uncovers actionable molecular alterations in cholangiocarcinoma.2015

    • Author(s)
      Arai Y, Nakamura H, Totoki Y, Shirota T, Hama N, Ojima H, Hosoda F, Shimada K, Morizane C, Okusaka T, Shibata T.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋市 名古屋国際会議場
    • Year and Date
      2015-10-09
    • Data Source
      KAKENHI-PROJECT-25290074
  • [Presentation] Genetic variations in primary breast cancer and its metastatic tumor.2012

    • Author(s)
      Fumie Hosoda
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] 乳がん原発巣とリンパ節転移巣における遺伝的変異の解析2012

    • Author(s)
      細田文恵、十時 泰、新井康仁、津田 均、 井本逸勢、稲澤譲治、大木 操、柴田龍弘
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Year and Date
      2012-09-21
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] Comparison of genetic alterations in primary breast cancer and its metastatic tumor2011

    • Author(s)
      Hosoda F, Totoki Y, et al
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] Comparison of genetic alterations in primary breast cancer and its metastatic tumor.2011

    • Author(s)
      Hosoda F, Totoki Y, Arai Y, Tsuda H, Imoto I, Inazawa J, Ohki M, Shibata T
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] 全ゲノムシークエンスによる肝癌のゲノム構造異常解析2010

    • Author(s)
      山本尚吾、十時 泰、薗田幸太郎、細田 文恵、白木原琢哉、辰野健二、柴田龍弘、油 谷浩幸
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] F-box and leucine-repeat protein 17(FBXL17)は新規のがん抑制遺伝子である2010

    • Author(s)
      新井康仁、細田文恵, ら
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] F-box and leucine-repeat protein 17 (FBXL17)は新規のがん抑制遺伝子である2010

    • Author(s)
      新井康仁、細田文恵、島 豊、中西幸浩、 柳原五吉、北林一生、大木 操、広橋説雄、 柴田龍弘
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪国際会議場(大阪市)
    • Year and Date
      2010-09-23
    • Data Source
      KAKENHI-PROJECT-22310123
  • [Presentation] Identification of aberrant long non-coding RNA transcripts in gastric cancer

    • Author(s)
      Hosoda F, Totoki Y, Arai Y, Hama N, Taniguchi H, Shibata T
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      横浜市 パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25290074
  • 1.  SHIBATA Tatsuhiro (90311414)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 2.  TOTOKI Yasushi (10373333)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 3.  TSUDA Hitoshi (70217321)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 4.  ARAI Yasuhito (80222727)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  TANIGUCHI Hirokazu (30415525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  ROKUTAN Hirofumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  堤 修一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  石川 俊平
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  油谷 浩幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  尾島 英知
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  稲澤 譲治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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