ITOH Tomoo 伊藤智夫

… Alternative Names

伊藤智夫イトウトモオ

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Researcher Number	30223168
Other IDs
Affiliation (Current)	2025: 北里大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2019: 北里大学, 薬学部, 教授 2002 – 2011: 北里大学, 薬学部, 教授 1999 – 2000: 北里大学, 薬学部, 教授
Review Section/Research Field	Principal Investigator Medical pharmacy / 医薬分子機能学
Keywords	Principal Investigator CYP3A4 / Caco-2細胞 / 定量的予測 / 経口投与 / 薬物相互作用 / 初回通過効果 / PEPT1 / Caco-2 cells / Oral Absorption / Transporter … More / ペニシリン系抗生物質 / 輸送担体 / 相互作用 / バイオアベイラビリティ / 小腸 / 薬学 / グルクロン酸抱合 / 薬物動態 / 薬物間相互作用 / human intestinal microsomes / small intestine / first-pass effect / ヒト小腸ミクロソーム / ACE inhibitors / sulfonylureas / cephems / penicillins / PepT1 / ACE阻害薬 / スルホニルウレア薬 / セフェム系抗生物質 / 経口吸収率 / Penicillins / Monocarboxylic Acid / モノカルボル酸 / 経口吸収 / モノカルボン酸 / 薬物相互 Less

Research Projects
(7 results)
Research Products
(101 results)

Quantitative prediction of oral bioavailability independent of metabolic pathwayPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kitasato University
Quantitative prediction of bioavailability and drug-drug interactions of orally administered drugsPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kitasato University
Quantitative prediction of first pass metabolism and drug-drug interactions for orally administered drugsPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kitasato University
Quantitative prediction of drug-drug interactions in the intestinal first pass metabolismPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kitasato University
Quantiative prediction of intestinal availability of CYP3A4 substratesPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kitasato University
Prediction of Oral Absorption of Anionic Drugs that are Absorbed by the Monocarboxylic Acid Transport SystemPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kitasato University
Prediction of Oral Absorption of Anionic Drugs that are Absorbed by the Monocarboxylic Acid Transport SystemPrincipal Investigator
- Principal Investigator
  
  ITOH Tomoo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Kitasato University

[Book] 第2章および第3章薬学共用試験(平成22年度)東京2011
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  NPO法人薬学共用試験センター
- Data Source
  KAKENHI-PROJECT-21590174
[Book] 第1章薬学共用試験の準備状況文部科学省医療人養成推進等委託事業薬学共用試験初年度の準備・実施状況および事後解析に関する調査・研究報告書東京2010
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  一般社団法人薬学教育協議会
- Data Source
  KAKENHI-PROJECT-21590174
[Book] 第2章および第3章薬学実務実習開始前の共用試験(平成21年度)東京2010
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  NPO法人薬学共用試験センター
- Data Source
  KAKENHI-PROJECT-21590174
[Book] 第2章薬学実務実習開始前の共用試験(平成20年度)東京2009
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  NPO法人薬学共用試験センター
- Data Source
  KAKENHI-PROJECT-21590174
[Book] 伊賀勝美・伊藤智夫・堀江利治(編) 対話と演習で学ぶ薬物速度論2008
- Author(s)
  伊藤智夫(分担執筆・編集)
- Publisher
  東京廣川書店
- Data Source
  KAKENHI-PROJECT-19590157
[Book] 対話と演習で学ぶ薬物速度論2008
- Author(s)
  伊賀勝美, 伊藤智夫, 堀江利治(編)
- Total Pages
  228
- Publisher
  廣川書店
- Data Source
  KAKENHI-PROJECT-19590157
[Book] 薬学実務実習開始前の共用試験 (平成19年度)2008
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  東京 NPO法人薬学共用試験センター
- Data Source
  KAKENHI-PROJECT-19590157
[Book] 薬学実務実習開始前の共用試験 (平成18年度)2007
- Author(s)
  伊藤智夫(分担執筆)
- Publisher
  東京 NPO法人薬学共用試験センター
- Data Source
  KAKENHI-PROJECT-19590157
[Book] パートナー薬剤学2007
- Author(s)
  伊藤智夫
- Total Pages
  30
- Publisher
  南江堂
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Analysis of inline-filter blockage with trastuzumab formulation using scanning-electron microscopy.2019
- Author(s)
  Ogawa C, Inoue M, Yatabe M, Nagayama Y, Gomi H, Nakadate K, Adachi S, Yachi Y, Itoh T.
- Journal Title
  
  Biomed. & Pharmacother.
  
  Volume: 112 Pages: 108711-108711
- DOI
  10.1016/j.biopha.2019.108711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08423, KAKENHI-PROJECT-17K08525
[Journal Article] Comparison of Chemical Behavior of Original and Generic Docetaxel Formulations as Non-alcoholic Preparations: Discussion about Diluent Solvents for Docetaxel2018
- Author(s)
  Ogawa C, Yatabe M, a, Inoue M, Hirose S, Ohashi Y, Yachi Y, Adachi S, Tomoo Itoh T.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 138 Issue: 7 Pages: 973-984
- DOI
  10.1248/yakushi.18-00006
- NAID
  130007386632
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-07-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08423
[Journal Article] Prediction of drug-induced liver injury using keratinocytes.2017
- Author(s)
  Hirashima R, Itoh T, Tukey RH, Fujiwara R.
- Journal Title
  
  J Appl Toxicol.
  
  Volume: 印刷中 Issue: 7 Pages: 863-872
- DOI
  10.1002/jat.3435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] Inhibition of UDP-glucuronosyltransferase (UGT)-mediated glycyrrhetinic acid 3-O-glucuronidation by polyphenols and triterpenoids.2017
- Author(s)
  Koyama M, Shirahata T, Hirashima R, Kobayashi Y, Itoh T, Fujiwara R.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 32(4): Issue: 4 Pages: 218-223
- DOI
  10.1016/j.dmpk.2017.04.003
- NAID
  210000185615
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08423
[Journal Article] Induction of the UDP-Glucuronosyltransferase 1A1 during the Perinatal Period Can Cause Neurodevelopmental Toxicity.2016
- Author(s)
  Hirashima R, Michimae H, Takemoto H, Sasaki A, Kobayashi Y, Itoh T, Tukey RH, Fujiwara R.
- Journal Title
  
  Mol Pharmacol.
  
  Volume: 90(3) Issue: 3 Pages: 265-74
- DOI
  10.1124/mol.116.104174
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] MicroRNA expression in the vildagliptin-treated two- and three-dimensional HepG2 cells.2016
- Author(s)
  Yamashita Y, Asakura M, Mitsugi R, Fujii H, Nagai K, Atsuda K, Itoh T, Fujiwara R.
- Journal Title
  
  Drug Metab Pharmacokinet.
  
  Volume: 31(3) Issue: 3 Pages: 201-9
- DOI
  10.1016/j.dmpk.2016.02.004
- NAID
  50014431262
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] Dipeptidyl peptidase-4 greatly contributes to the hydrolysis of vildagliptin in human liver.2015
- Author(s)
  Asakura M, Fujii H, Atsuda K, Itoh T, Fujiwara R.
- Journal Title
  
  Drug Metab. Dispos.
  
  Volume: 43 Issue: 4 Pages: 477-84
- DOI
  10.1124/dmd.114.062331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8.2015
- Author(s)
  Takagi M, Sakamoto M, Itoh T, Fujiwara R.
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 30 Issue: 4 Pages: 288-94
- DOI
  10.1016/j.dmpk.2015.05.001
- NAID
  210000180871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] Nicotine regulates the expression of UDP-glucuronosyltransferase (UGT) in humanized UGT1 mouse brain.2015
- Author(s)
  Sakamoto M, Itoh T, Tukey RH, Fujiwara R.
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 30 Issue: 4 Pages: 269-75
- DOI
  10.1016/j.dmpk.2015.04.004
- NAID
  50014429962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460204, KAKENHI-PROJECT-26870562
[Journal Article] Extensive protein-protein interactions involving cytochrome P450 3A4: a poosible contributor the fromation of metabolosome.2014
- Author(s)
  Fujiwara R and Itoh T.
- Journal Title
  
  Pharmacol Res Perspect.
  
  Volume: 2 Issue: 5 Pages: 1-5
- DOI
  10.1002/prp2.53
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460204
[Journal Article] Differences in the pharmacokinetics of 4-amino-3-chlorophenyl hydrogen sulfate, a metabolite of Resatorvid, in rats and dogs2012
- Author(s)
  Jinno F, Takeuchi T, Tagawa Y, Kondo T, Itoh T and Asahi S.
- Journal Title
  
  Drug Metab. Disp.
  
  Volume: 40 Pages: 648-654
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] 抗がん剤後発医薬品の適正使用への問題点と問題解決への新たな視点第3報:薬剤師を中心としたアンケート調査結果から2010
- Author(s)
  今井康人, 飯島肇, 蓮沼智子, 山田好則, 渡邉誠, 武藤正樹, 鈴木順子, 伊藤智夫
- Journal Title
  
  臨床医薬
  
  Volume: 26 Pages: 425-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] 抗がん剤後発医薬品の適正使用への問題点と問題解決への新たな視点第3報薬剤師 : を中心としたアンケート調査結果から2010
- Author(s)
  今井康人, 飯島肇, 蓮沼智子, 山田好則, 渡邉誠, 武藤正樹, 鈴木順子, 伊藤智夫
- Journal Title
  
  臨床医薬
  
  Volume: 26(6) Pages: 425-433
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] 抗がん剤後発医薬品の適正使用への問題点と問題解決への新たな視点2010
- Author(s)
  今井康人, 飯島肇, 蓮沼智子, 山田好則, 渡邉誠, 武藤正樹, 鈴木順子, 伊藤智夫
- Journal Title
  
  臨床医薬
  
  Volume: 26 Pages: 297-306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] 抗がん剤後発医薬品の適正使用への問題点と問題解決への新たな視点2010
- Author(s)
  今井康人, 飯島肇, 蓮沼智子, 山田好則, 渡邉誠, 武藤正樹, 鈴木順子, 伊藤智夫
- Journal Title
  
  臨床医薬
  
  Volume: 26(4) Pages: 297-306
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] Stereoselective transport of amethopterin enantiomers by the proton-coupled folate transporter.2010
- Author(s)
  T.Narawa, T.Itoh
- Journal Title
  
  Drug Metab.Pharamacokinet.
  
  Volume: 25 Pages: 283-289
- NAID
  10027582937
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] Stereoselective transport of amethopterin enantiomers by the proton-coupled folate transporter2010
- Author(s)
  Narawa T, Itoh T
- Journal Title
  
  Drug Metab. Pharmacokin (in press)
- NAID
  10027582937
- Data Source
  KAKENHI-PROJECT-19590157
[Journal Article] Stereoselective transport of amethopterin enantiomers by the proton-coupled folate transporter2010
- Author(s)
  Narawa T, Itoh T.
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 25 Pages: 283-289
- NAID
  10027582937
- Data Source
  KAKENHI-PROJECT-21590174
[Journal Article] Quantitative Prediction of Oral Absorption of PEPT1 Substrates Based on in vitro Uptake into Caco-2 Cells2008
- Author(s)
  R.Shimizu, T.Sukegawa, Y.Tsuda, T.Iitoh
- Journal Title
  
  Int.J.Pharmaceut. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590157
[Journal Article] Quantitative Prediction of Oral Absorption of PEPT1 Substrates Based on in vitro Uptake into Caco-2 Cells.2008
- Author(s)
  R. Shimizu, T. Sukegawa, Y. Tsuda, T. Itoh
- Journal Title
  
  Int. J. Pharmaceut. 354
  
  Pages: 104-110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590157
[Journal Article] Quantitative Prediction of Oral Absorption of PEPT1 Substrates Based on in vitro Uptake into Caco-2 Cells2008
- Author(s)
  Shimizu R, Sukegawa T, Tsuda Y, Itoh T
- Journal Title
  
  Int J Pharmaceut 354
  
  Pages: 104-110
- Data Source
  KAKENHI-PROJECT-19590157
[Journal Article] Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.2007
- Author(s)
  T.Narawa, Y.Tsuda, T.Itoh
- Journal Title
  
  Drug Metab. Pharmacokinet. 22・1
  
  Pages: 33-40
- NAID
  10018732926
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells2007
- Author(s)
  T. Narawa, Y. Tsuda, T. Itoh
- Journal Title
  
  Drug Metab.Pharmacokinet. 22・1
  
  Pages: 33-40
- NAID
  10018732926
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Chiral recognition of amethopterin enantiomers by the reduced folate carrier in Caco-2 cells.2007
- Author(s)
  NarawaT., Tsuda Y., Itoh T.
- Journal Title
  
  Drug Metab. Pharmacoldnet. 22(1)
  
  Pages: 33-40
- NAID
  10018732926
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Quantitative prediction of human intestinal availability of CYP3A4 substrates based on unbound concentration.2006
- Author(s)
  Y.Iwase, T.Itoh
- Journal Title
  
  JSSX Annual Meeting Abstracts.
  
  Pages: 286-286
- NAID
  130005442553
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Prediction of intestinal first-oass effect based on a CAT model.2006
- Author(s)
  M.Ishi.ii, Y.Iwase, T.Itoh
- Journal Title
  
  JSSX Annual Meeting Abstracts.
  
  Pages: 237-237
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Quantitative prediction of human intestinal availability of CYP3A4 substrates2005
- Author(s)
  Y.Iwase, Y.Tsuda, T.Itoh
- Journal Title
  
  JSSX-ISSX Joint Conference Abstracts
  
  Pages: 401-401
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Stereoselectivity of the reduced folate carrier in Caco-2 cells.2005
- Author(s)
  T.Narawa, T.Itoh
- Journal Title
  
  Chirality 17
  
  Pages: 444-449
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Stereoselectivity of the reduced fblate carrier in Caco-2 cells2005
- Author(s)
  T. Narawa, T. Itoh
- Journal Title
  
  Chirality 17
  
  Pages: 444-449
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Stereoselectivity of the Reduced Folate Carrier in Caco-2 cells.2005
- Author(s)
  Narawa T, Shimizu R, Takano S, Tsuda Y, Ono K, Ymada H, Itoh T
- Journal Title
  
  Chirality 17(8)
  
  Pages: 444-449
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Journal Article] Prediction of oral absorption of PEPT1 substrates2004
- Author(s)
  Matsuzaki Y., Shimizu R., Takano S., Itoh T.
- Journal Title
  
  PSWC Abstracts
  
  Pages: 126-126
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Oral absorption of PEPT1 substrates can be predicted in vitro2004
- Author(s)
  Shimizu R., Matsuzaki Y., Takano S., Itoh T.
- Journal Title
  
  MMT3D Abstracts
  
  Pages: 48-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] PEPT1発見細胞を用いた経口吸収率の予測2003
- Author(s)
  松崎裕子, 清水理桂子, 高野修平, 伊藤智夫
- Journal Title
  
  第18回日本薬物動態学会年会講演要旨集
  
  Pages: 284-284
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Oral absorption of cephalosporins in quantitatively predicted from in vitro uptake into intestinal brush border membrane vesicles.2001
- Author(s)
  Kohda-Shimizu R., Li Y-H., ・・・・・・, Yamada H., Itoh T.
- Journal Title
  
  Int. J. Pharmaceut. 220
  
  Pages: 119-128
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Oral absorption of cephalosporins is quantitatively predicted from in vitro uptake into intestinal brush border membrane vesicles.2001
- Author(s)
  Kohda-Shimizu R., Li Y-H., Shitara Y., Ito K., Tsuda Y., Yamada H., Itoh T.
- Journal Title
  
  Int.J.Pharmaceut. 220
  
  Pages: 119-128
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into HeLa-PEPT1 cells.
- Author(s)
  Matsuzaki Y., Shimizu R., Tsuda Y., Itoh T.
- Journal Title
  
  J.Pharmacol.Exp.Therap. (in preparation)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into Caco-2 cells.
- Author(s)
  Shimizu R., Sukegawa T., Tsuda Y., Yamada H., Itoh T.
- Journal Title
  
  Drug Mtab. Pharmacokinet. (submitted)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into Caco-2 cells.
- Author(s)
  Shimizu R., Sukegawa T., Tsuda Y., Yamada H., Itoh T.
- Journal Title
  
  Drug Mtab.Pharmacokinet. (submitted)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Journal Article] Quantitative prediction of oral absorption of PEPT1 substrates based on in vitro uptake into HeLa-PEPT1 cells.
- Author(s)
  Matsuzaki Y., Shimizu R., Tsuda Y., Itoh T.
- Journal Title
  
  J. Pharmacol. Exp. Therap. (in preparation)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14572097
[Presentation] PCFTを介した葉酸輸送におけるワインの影響2020
- Author(s)
  奈良輪知也、山岡杏里、伊藤智夫
- Organizer
  日本薬学会第140年会　京都
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] UDP-グルクロン酸転移酵素 (UGT) 1および2ノックアウトマウスを用いた内因性基質のグルクロン酸抱合の解析2020
- Author(s)
  若月梨子、伊藤智夫
- Organizer
  日本薬学会第140年会　京都
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] 大豆抽出物によるOATP2B1の輸送阻害機構の解明2020
- Author(s)
  高野修平、石光遥奈、高橋菜月、渡邉真衣子、伊藤智夫
- Organizer
  日本薬学会第140年会　京都
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] OATP2B1を介したestrone-3-sulfateの輸送に対するルイボスティーの影響2019
- Author(s)
  高野修平、大川春菜、伊藤智夫
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] PCFTを介した葉酸輸送に対するカフェインフリー飲料の影響2019
- Author(s)
  奈良輪知也、山科知実、伊藤智夫
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] PCFTを介した葉酸輸送に対する種々ハーブティーの影響2018
- Author(s)
  奈良輪知也、伊藤智夫
- Organizer
  日本薬学会第138年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] OATP2B1によるestrone-3-sulfateの輸送におけるHis618の役割2018
- Author(s)
  高野修平、室山祐理子、伊藤智夫
- Organizer
  日本薬学会第138年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] フラボノイド類によるPCFTを介した葉酸吸収阻害とその種差2018
- Author(s)
  田中雛乃、奈良輪知也、伊藤智夫
- Organizer
  日本薬学会第138年会（金沢）
- Data Source
  KAKENHI-PROJECT-17K08423
[Presentation] 免疫抑制剤による皮膚発がん誘導メカニズムの解明2017
- Author(s)
  平島梨夏、田中優史、藤原亮一、伊藤智夫
- Organizer
  日本薬学会第137年会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-26460204
[Presentation] ヘムオキシゲナーゼ-1（HO-1）阻害剤を用いたCrigler-Najjar症候群Ⅰ型の致死性回避2017
- Author(s)
  植村明日香、三ツ木諒、藤原亮一、伊藤智夫
- Organizer
  日本薬学会第137年会
- Place of Presentation
  宮城県仙台市
- Data Source
  KAKENHI-PROJECT-26460204
[Presentation] HepG2細胞におけるmiR-877の機能解析2016
- Author(s)
  三ツ木諒、藤原亮一、伊藤智夫
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460204
[Presentation] ２型糖尿病治療薬ビルダグリプチンによるS100A8/A9の発現誘導2016
- Author(s)
  朝倉充俊、藤原亮一、藤井秀明、厚田幸一郎、伊藤智夫
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460204
[Presentation] 肝細胞の三次元培養技術を応用したビルダグリプチン誘導性マイクロRNA発現誘導解析2016
- Author(s)
  山下康也、朝倉充俊、藤原亮一、藤井秀明、厚田幸一郎、伊藤智夫
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-26460204
[Presentation] ITAM-PKモデルを用いたエリスロマイシンとトリアゾラムの相互作用の予測2012
- Author(s)
  徳重枝里子、菅谷藍、伊藤智夫
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] Ritonavir併用時におけるCYP3A4基質のヒト小腸初回通過効果の予測2011
- Author(s)
  金森基泰, 伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] Ritonavir併用時におけるCYP3A基質のヒト小腸初回通過効果の予測2011
- Author(s)
  金森基泰、伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] フェロジピンとキニジンの小腸アベイラビリティの定量的予測2011
- Author(s)
  吉川慧、外川雄貴、伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  ツインメッセ静岡(静岡市)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ヒトRFCの立体選択的輸送に対するSNPの影響2011
- Author(s)
  奈良輪知也, 柳沢秀明, 伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] OATP2B1のestrone-3-sulfateの輸送におよぼすArg607の関与2011
- Author(s)
  高野修平, 造力由佳, 加納和彦, 竹田-志鷹真由子, 梅山秀明, 伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ラットPCFTの立体選択性の解明2011
- Author(s)
  矢野敏明, 奈良輪知也, 伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] フェロジピンとキニジンの小腸アベイラビリティの定量的予測2011
- Author(s)
  吉川慧, 外川雄貴, 伊藤智夫
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ニフェジピンの小腸アベイラビリティの定量的予測2010
- Author(s)
  吉川慧, 伊藤智夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ニフェジピンの小腸アベイラビリティの定量的予測2010
- Author(s)
  吉川慧、伊藤智夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山桃太郎アリーナ(岡山市)
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] リトナビルによるCYP3A阻害の検討2010
- Author(s)
  金森基泰、伊藤智夫
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  大宮ソニックシティー(さいたま市)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ニフェジピンの小腸アベイラビリティの定量的予測2010
- Author(s)
  吉川慧, 伊藤智夫
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] CYP3A4基質の小腸アベイラビリティの定量的予測2010
- Author(s)
  吉川慧、伊藤智夫
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  大宮ソニックシティー(さいたま市)
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ラット皮膚ミクロソームを用いたin vitro代謝実験2010
- Author(s)
  高野絵美, 伊藤智夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] PAMPAを用いた小腸アベイラビリティの定量的予測2010
- Author(s)
  西矢博紀, 伊藤智夫
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] リトナビルによるCYP3A4阻害の検討2010
- Author(s)
  金森基泰, 伊藤智夫
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-21590174
[Presentation] ラットにおけるCYP3A基質の小腸アベイラビリティの検討2008
- Author(s)
  野口直子, 津田泰之, 伊藤智夫
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] CONSTRUCTION OF A THREE-DIMENTIONAL MODEL AND PREDICTION OF THE SUBSTRATE-BINDING SITES OF OATP2B12008
- Author(s)
  Takano S., Uchida M., Kanou K., Takeda-Shitaka M., Umeyama H., Itoh T.
- Organizer
  第23回日本薬物動態学会年会
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] ヒトPGFT/HGP1の立体選択性2008
- Author(s)
  奈良輪知也, 伊藤智夫
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  札幌
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Reduced Folate Carrier (RFC) の基質認識における立体選択性の解明2008
- Author(s)
  柳沢秀明, 奈良輪知也, 伊藤智夫
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Midazolam によるヒトCYP3Aの不可逆的阻害2008
- Author(s)
  岩瀬由未子, 津田泰之, 伊藤智夫
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] 薬物輸送担体の立体選択性2008
- Author(s)
  伊藤智去
- Organizer
  Symposium on Molecular Chirality
- Place of Presentation
  岡山
- Year and Date
  2008-05-23
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] シンポジウム : 薬学教育改革最前線「共用試験トライアルの状況」2008
- Author(s)
  宮崎智, 伊藤智夫, 伊藤喬, 山元弘, 入江徹美
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Proton-coupled folate transporter /Heme carrier protein 1の立体選択的輸送2008
- Author(s)
  奈良輪知也, 田中裕子, 柳沢秀明, 伊藤智夫
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Prediction of human intestinal availability of CYP3A4 substrates based on in vitro studies 4^<th> World Conference on Drug Absorption2007
- Author(s)
  Iwase Y, Ishiji M, Tsuda Y, Itoh T
- Organizer
  Transport and Delivery
- Place of Presentation
  Kanazawa
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] ホモロジーモデリングによるOATP2B1の基質結合部位の推定2007
- Author(s)
  内田めぐみ, 高野修平, 加納和彦, 竹田一志, 鷹真由子, 梅山秀明, 伊藤智夫
- Organizer
  第2回トランスポーター研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Prediction of intestinal availability of alprazolam in rats2007
- Author(s)
  Noguchi N, Tsuda Y, Itoh T
- Organizer
  8^<th> International ISSX Meeting (Senadai)
- Year and Date
  2007-10-12
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Stereo selectivity of the proton-coupled folate transporter/heme carrier protein 1 (PCFT/HCP1)2007
- Author(s)
  Narawa T, Yanagisawa H, Tsuda Y, Itoh T
- Organizer
  8^<th> International ISSX Meeting (Senadai)
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Stereoselective transport of amethopterin enantiomers by reduced folate carrier 12007
- Author(s)
  Yanagisawa H, Narawa T, Itoh T
- Organizer
  8^<th> International ISSX Meeting (Senadai)
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] Stereoselective transport system of amethopterin enantiomers 4^<th> World Conference on Drug Absorption2007
- Author(s)
  Narawa T, Yanagisawa H, suda Y, Itoh T
- Organizer
  Transport and Delivery
- Place of Presentation
  Kanazawa
- Year and Date
  2007-06-20
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] CATモデルに基づいた小腸初回通過代謝における薬物間相互作用の予測2007
- Author(s)
  岩瀬由未子、石地正隆、伊藤智夫
- Organizer
  日本薬剤学会第20年会
- Place of Presentation
  さいたま市(埼玉県)
- Data Source
  KAKENHI-PROJECT-19590157
[Presentation] INDUCTION OF CYP3A BY DEXAMETHASONE IN RAT SMALL INTESTINE AND LIVER.2006
- Author(s)
  Saitoh M., Ohsawa M., Takano S., Tsuda Y., Itoh T.
- Organizer
  21st JSSX Annual Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-11-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Involvment of a calcium/calmodulin mediated pathway in the regulation of the transport activity of estrone-3-sulfate in Caco-2 cells.2006
- Author(s)
  Takano S., Uchida M., Itoh T.
- Organizer
  21st JSSX Annual Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Regulation of OATP2B1(OATP-B) activity by signal transduction pathways.2006
- Author(s)
  Uchida M., Takano S., Itoh T.
- Organizer
  21st JSSX Annual Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Prediction of intestinal first-pass effect based on a CAT model2006
- Author(s)
  M. Ishiji, Y. Iwase, T. Itoh
- Organizer
  21st JSSX Annual Meeting[Abstract p.237]
- Place of Presentation
  Tokyo
- Year and Date
  2006-11-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Quantitative prediction of human intestinal availability of CYP3A4 substrates based on unbound concentration.2006
- Author(s)
  Iwase Y., Isiji M., Narawa T., Tsuda Y., Itoh T.
- Organizer
  21st JSSX Annual Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-11-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Prediction of intestinal first-pass effect based on a CAT model.2006
- Author(s)
  Ishiji M., Iwase Y. and Itoh T.
- Organizer
  21st JSSX Annual Meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-11-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Stereoselective Transport of Reduced Folate Carrier 12005
- Author(s)
  Narawa T, Takano S, Tsuda Y, Itoh T
- Organizer
  13th NA ISSX/20th JSSX Meeting
- Place of Presentation
  Maui, U.S.A
- Year and Date
  2005-11-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Regulation of PEPT1 Activity by Protein Kinase C2005
- Author(s)
  Takano S, Itoh T
- Organizer
  13th NA ISSX/20th JSSX Meeting
- Place of Presentation
  Maui, U.S.A
- Year and Date
  2005-10-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135
[Presentation] Quantitative Prediction of Human Intestinal Availability of CYP3A4 Substrates2005
- Author(s)
  Iwase Y, Tsuda Y, Itoh T
- Organizer
  13th NA ISSX/20th JSSX Meeting
- Place of Presentation
  Maui, U.S.A
- Year and Date
  2005-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590135

ITOH Tomoo 伊藤 智夫

伊藤 智夫 イトウ トモオ

Research Projects

Research Products

Quantitative prediction of oral bioavailability independent of metabolic pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

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Quantitative prediction of bioavailability and drug-drug interactions of orally administered drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Quantitative prediction of first pass metabolism and drug-drug interactions for orally administered drugsPrincipal Investigator

Principal Investigator

Project Period (FY)

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Quantitative prediction of drug-drug interactions in the intestinal first pass metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

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Quantiative prediction of intestinal availability of CYP3A4 substratesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction of Oral Absorption of Anionic Drugs that are Absorbed by the Monocarboxylic Acid Transport SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prediction of Oral Absorption of Anionic Drugs that are Absorbed by the Monocarboxylic Acid Transport SystemPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 第2章および第3章薬学共用試験(平成22年度)東京2011

Author(s)

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[Book] 第1章薬学共用試験の準備状況文部科学省医療人養成推進等委託事業 薬学共用試験初年度の準備・実施状況および事後解析に関する調査・研究報告書東京2010

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[Book] 第2章および第3章薬学実務実習開始前の共用試験(平成21年度)東京2010

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[Book] 第2章薬学実務実習開始前の共用試験(平成20年度)東京2009

Author(s)

Publisher

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[Book] 伊賀勝美・伊藤智夫・堀江利治(編) 対話と演習で学ぶ 薬物速度論2008

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[Book] 対話と演習で学ぶ 薬物速度論2008

Author(s)

Total Pages

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[Book] 薬学実務実習開始前の共用試験 (平成19年度)2008

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Publisher

Data Source

[Book] 薬学実務実習開始前の共用試験 (平成18年度)2007

Author(s)

Publisher

Data Source

[Book] パートナー薬剤学2007

ITOH Tomoo 伊藤智夫

伊藤智夫イトウトモオ

[Book] 第1章薬学共用試験の準備状況文部科学省医療人養成推進等委託事業薬学共用試験初年度の準備・実施状況および事後解析に関する調査・研究報告書東京2010

[Book] 伊賀勝美・伊藤智夫・堀江利治(編) 対話と演習で学ぶ薬物速度論2008

[Book] 対話と演習で学ぶ薬物速度論2008