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NAITO Etsuo  内藤 悦雄

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Researcher Number 30227706
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Affiliation (based on the past Project Information) *help 2008 – 2009: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 非常勤講師
2007: The University of Tokushima, 大学ヘルスバイオサイエンス研究部, 非常勤講師
2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 非常勤講師
2005: 徳島大
2004: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授 … More
2002 – 2003: 徳島大学, 医学部, 助教授
1998 – 2001: 徳島大学, 医学部, 講師
1996: The University of Tokushima, Department of Pediatrics, Instructor, 医学部・付属病院, 講師
1996: 徳島大学, 医学部・附属病院, 講師
1993 – 1995: 徳島大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Pediatrics / Pediatrics
Keywords
Principal Investigator
Leigh脳症 / ミトコンドリアDNA異常症 / Leigh syndrome / 先天性高乳酸血症 / 高乳酸血症 / [1-^<14>C]ピルビン酸脱炭酸能 / PDHC異常症 / pyruvate dehydrogenase complex deficiency / decarboxylation rate of [1-^<14>C] pyruvate / mitochondrial DNA disease … More / SURF-1遺伝子変異 / 複合体IV欠損症 / [1-^<14>Cピルビン酸脱炭酸能 / Mitochondrial disease / Lactic acidomia / ミトコンドリア異常症 / E1 alpha deficiency / Pyruvate dehydrogenase complex deficiency / thiamine / Congenital lactic acidemia / E_1a異常症 / ビタミンB_1 / E_1α異常症 / ピルビン酸脱水素酵素複合体 / Respiratory chain desfunction / Pyruvate dehydrogenase deficiency / Cultured lymphoblastoid cells / Congeital lactic acidemia / Enzymatic diagnosis / ピルビン酸カルボキシラーゼ欠損症 / 酵素診断 / ピルビン酸脱水素酵素複合体欠損症 / 電子伝達系酵素異常症 / 系統的酵素診断法 / 培養リンパ球 / 有機酸代謝異常症 / 蛋白質 / 高乳酸血漿 / ビタミンB1 / ジクロロ酢酸ナトリウム / ミトコンドリア機能 / 高ピルビン酸血症 / 脳・神経 Less
  • Research Projects

    (6 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (1 People)
  •  Diagnosis and treatment in the new mitochondrial dysfunction causing to Leigh syndromePrincipal Investigator

    • Principal Investigator
      NAITO Etsuo
    • Project Period (FY)
      2006 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The University of Tokushima
  •  新たなミトコンドリア機能異常に基づくLeigh脳症の解明とその薬物療法の確立Principal Investigator

    • Principal Investigator
      内藤 悦雄
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The University of Tokushima
  •  Study of mitochondorial disease with Leigh syndrome and the therapyPrincipal Investigator

    • Principal Investigator
      NAITO Etsuo
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The University OF Tokushima
  •  Defects and treatment in patients with Leigh syndromePrincipal Investigator

    • Principal Investigator
      ETSUO Naito
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      University of Tokushima
  •  Biochemical analysis and therapy of thiamine-responsive lactic acidemiaPrincipal Investigator

    • Principal Investigator
      NAITO Etsuo
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      The University of Tokushima
  •  Enzymatic diagnosis of patients with congenital lactic acidemia on cultured lymphoblastoid cellsPrincipal Investigator

    • Principal Investigator
      NAITO Etsuo
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      University of Tokushima

All 2009 2008 2007 2006 2004

All Journal Article Presentation

  • [Journal Article] 高乳酸・ピルビン酸血症2009

    • Author(s)
      内藤悦雄
    • Journal Title

      小児内科 41

      Pages: 369-375

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Treatment for Leigh syndrome by monitoring dichloroacetate concentration2009

    • Author(s)
      Naito E, et al.
    • Journal Title

      Pediatrics International 51

      Pages: 293-295

    • NAID

      10028180274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Treatment for Leigh syndrome by monitoring dichloroacetate concentration2009

    • Author(s)
      Masafumi Morimoto, Akira Nishimura, Etsuo Naito, TohrunSugimoto
    • Journal Title

      Pediatrics International Vol51

      Pages: 293-312

    • NAID

      10028180274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] タンデム質量計による新生児マス・スクリーニングが早期発見・治療に有用であったグルタル酸血症I型女児例2008

    • Author(s)
      内藤悦雄
    • Journal Title

      特殊ミルク情報 44

      Pages: 9-12

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Developpment of a new enzymatic diagnosis method for very-long-chain acyl-CoA dehydrogenase deficiency by detecting 2-hexadecenoyl-CoA production and its application in tandem mass spectrometry-based selective screening and newborn screening in Japan2008

    • Author(s)
      Go Tajima, Nobuo Sakura, Kenichiro Shirao, Satoshi Okada, Miyuki Tsumura, Yutaka Nishimura, Hiroaki Ono, Yuki Hasegawa, Ikue Hata, Etsuo Naito, Seiji Yamaguchi, Yosuke Shigematsu, Nasao Kobayashi
    • Journal Title

      Pediatric Research Vol64.No6

      Pages: 667-672

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] タンデム質量分析計による新生児マス・スクリーニングが早期発見・治療に有用であったグルタル酸血症I型女児例2008

    • Author(s)
      内藤 悦雄
    • Journal Title

      特殊ミルク情報 44

      Pages: 9-12

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Serial brain imaging analysis of stroke-like episodes in mus2008

    • Author(s)
      Hiromichi Ito, Kenji Mori, Masafumi Harada, Masako Minato, Etsuo Naito, Mayumi Takeuchi, Yasuhiro Kuroda, Shoji Kagami
    • Journal Title

      Vol30

      Pages: 483-488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Pathophysiology of the transient temporal lobe lesion in a patient with Menkes disease2008

    • Author(s)
      Hiromichi Ito, Kenji Mori, Miho Sakata, Etsuo Naito, Masafumi Harada, Masako Minato, Hiroko Kodama, Yan-Hong Gu, Yasuhiro Kuroda, Shoji Kagami
    • Journal Title

      Vol30

      Pages: 483-488

    • NAID

      10025345698

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] ミトコンドリア異常症2007

    • Author(s)
      内藤 悦雄
    • Journal Title

      小児内科増刊号 39

      Pages: 529-532

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] ミトコンドリア異常症2007

    • Author(s)
      内藤悦雄
    • Journal Title

      小児内科増刊号 39

      Pages: 529-532

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] 代謝性アシドーシスの治療2006

    • Author(s)
      内藤悦雄
    • Journal Title

      小児科診療 69

      Pages: 684-1689

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] ブドウ糖負荷試験2006

    • Author(s)
      内藤悦雄
    • Journal Title

      小児内科 38

      Pages: 1475-1177

    • Data Source
      KAKENHI-PROJECT-18591155
  • [Journal Article] Genetic background markedly influences vulnerability of the hippocampal neuronal organization in the "twitcher" mouse model of globoid cell leukodystrophy2004

    • Author(s)
      Tominaga K, Matsuda J, Kido M, Naito E, Yokota I, Toida K, Ishimura K, Suzuki K, Kuroda Y.
    • Journal Title

      J.Neurosci.Res. 77

      Pages: 507-516

    • Data Source
      KAKENHI-PROJECT-16591033
  • [Presentation] Defects of pyruvate metabolism in cultured lymphoblastoid cells from 70 Japanese patients with Leigh syndrome.2009

    • Author(s)
      Etsuo Naito, T. liashimoto, Y. Kotani, S. Kagami
    • Organizer
      59th American Society of Human Genetics
    • Place of Presentation
      Honolulu, Hawaii
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] 日本人105例のピルビン酸脱水素酵素複合体異常症の酵素診断遺伝子診断とその臨床像2009

    • Author(s)
      内藤悦雄, 西村美緒, 島川清司, 橋本俊顕, 小谷裕美子, 香美祥二
    • Organizer
      日本小児神経学会総会
    • Place of Presentation
      米子
    • Year and Date
      2009-05-29
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] Defects of pyruvate metabolism in cultured lymphoblastoid cells from 70 Japanese patients with Leigh syndrome2009

    • Author(s)
      Etsuo Naito
    • Organizer
      The American Society of Human Genetics
    • Place of Presentation
      ハワイ コンベンションセンター(ホノルル)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] 徳島県におけるタンデムマスによる新生児マススクリーニングの10年間の経過2009

    • Author(s)
      内藤悦雄, 大山江里子, 小谷裕美子, 香美祥二, 重松陽介
    • Organizer
      第133回目本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] 最近4年間で遺伝子診断した先天代謝異常症30例の臨床像2008

    • Author(s)
      内藤悦雄, 小谷裕美子, 香美祥二, 重松陽介
    • Organizer
      第131回日本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2008-12-07
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] ジクロロ酢酸ナトリウム療法を14年間継続し得たピルビン酸脱水素酵素欠損症の1女児例2007

    • Author(s)
      内藤悦雄, 西村美緒, 島川清司, 中川竜二
    • Organizer
      第129回日本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2007-06-09
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] 死亡6年後に確定診断ができたピルビン酸脱水素酵素欠損症の1男児例2007

    • Author(s)
      内藤悦雄, 奥村恵子, 小谷裕美子, 品原久美, 香美祥二
    • Organizer
      第131回日本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2007-12-09
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] Mutation analysis of the pyruvate dehydrogenase E1 alpha gene in 70 Japanese patients with a pyruvate dehydrogenase complex deficiency.2007

    • Author(s)
      Etsuo Naito, T. Hashimoto, Y. Kotani, S. Kagami
    • Organizer
      57th American Society of Human Genetics
    • Place of Presentation
      San Diego CA.
    • Year and Date
      2007-10-25
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] Defects of pyruvate metabolism in cultured lymphoblastoid cells from 64 Japanese patients with Leigh syndrome.2007

    • Author(s)
      Etsuo Naito, T. Hashimoto, Y. Kotani, S. Kagami
    • Organizer
      9th Asian Oceanian Congress of Child Neurology
    • Place of Presentation
      Cebu City, Philippines
    • Year and Date
      2007-01-26
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] ジクロロ酢酸ナトリウム療法を13年間続けたG291R変異を有したピルビン酸脱水素酵素欠損症の1女児例2007

    • Author(s)
      内藤悦雄, 西村美緒, 島川清司
    • Organizer
      日本小児神経学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-06
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] チロシン血症III型と思われる1女児例2006

    • Author(s)
      内藤悦雄, 小谷裕美子, 品原久美, 香美祥二
    • Organizer
      第127回日本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2006-12-06
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] Biochemical and molecular analysis of 14 patients with thiamin-responsive pyruvate dehydrogenase deficiency.2006

    • Author(s)
      Etsuo Naito, T. Hashimoto, Y. Kotani, S. Kagami
    • Organizer
      56th American Society of Human Genetics
    • Place of Presentation
      New Orleans, LA
    • Year and Date
      2006-10-10
    • Data Source
      KAKENHI-PROJECT-18591155
  • [Presentation] タンデムマス質量分析計による新生児マススクリーニングで発見されたメチルマロン酸血症の1女児例2006

    • Author(s)
      内藤悦雄, 小谷裕美子, 品原久美, 香美祥二, 重松陽介, 但馬剛
    • Organizer
      第126回日本小児科学会徳島地方会
    • Place of Presentation
      徳島
    • Year and Date
      2006-06-17
    • Data Source
      KAKENHI-PROJECT-18591155
  • 1.  KURODA Yasuhiro (20035471)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 1 results

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