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NAKAE Hideaki  中江 英明

ORCIDConnect your ORCID iD *help
… Alternative Names

中江 英明  ナカエ ヒデアキ

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Researcher Number 30227730
External Links
Affiliation (based on the past Project Information) *help 2012: 徳島大学, 大学院・ヘルスバイオサイエンス 研究部, 准教授
2007 – 2011: The University of Tokushima, Institute of Health Biosciences, Graduate School, Associate professor
2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助教授
2004 – 2005: The University of Tokushima, Institute of Health Biosciences of Tokushima Graduate School, Department of Conservative Dentistry, Associate Professor, 大学院・ヘルスバイオサイエンス研究部, 助教授
2000 – 2003: Univ.of Tokushima, Conserv.Dent., Assistant professor, 歯学部, 助教授 … More
1999: Tokushima Univ., Conserv. Dent., Assistant professor, 歯学部・附属病院, 講師
1998: 徳島大学, 歯学部, 講師
1998: 徳島大学, 歯学部附属病院, 講師
1996: 徳島大学, 歯学部・附属病院, 講師
1993: 徳島大学, 歯学部・附属病院, 講師
1993: Tokushima University, University Dental Hospital, Assistant Professor, 歯学部附属病院, 講師
1990 – 1992: 徳島大学, 歯学部, 助手 Less
Review Section/Research Field
Principal Investigator
Periodontal dentistry / Periodontal dentistry
Except Principal Investigator
Conservative dentistry / Conservative dentistry / Periodontal dentistry
Keywords
Principal Investigator
claudin / 線維芽細胞 / 上皮細胞 / IL-8 / tight junction / クローディン / 共培養 / 歯周病関連細菌 / RT-PCR / ICAM-1 … More / PIPAAm / adherence junction / cadherin / JAM-A / MMP / 歯周炎 / ケモカイン / オクルーディン / シグナル伝達 / in situPCR / 接合上皮 / MAPキナーゼ / in situ PCR / in situ / 免疫染色 / 歯周ポケット / 侵入 / Periodontopathic bacteria / in situ-PCR / Junctional epithelium / MAP kinase / 歯肉上皮細胞 / 三次元培養 / 歯肉線維芽細胞 / tight junctio / 3次元培養 / gingival epithelial cell / three-dimensional culture / gingival fibroblast / 歯周病 / タイトジャンクション / tight-junction / トランスフェクション / fight iunction / epithelial cell / periodontal disease … More
Except Principal Investigator
バイオフィルム / 歯髄炎 / 免疫染色 / 歯周炎 / マクロファージ / リンパ球 / 接着分子 / 象牙細管 / 根尖性歯周炎 / 細菌 / 遺伝子発現 / シグナル伝達 / 歯周ポケット内細菌 / 歯周病関連細菌 / 感染根管 / 難治性根尖性歯周炎 / Immunohistology / 線維芽細胞 / MCP-1 / MMP-1 / Macrophage / MIP-3α / CCR6 / ケモカイン / pulpitis / chemokine / histon-like protein / Porphyromonas gingivalis / biofilm / suicide vector / anaerobic system / antibody / Woodruff assay / 象牙質齲蝕 / 齲蝕原性細菌 / クオラムセンシング / 根面齲蝕 / ミュータンス菌 / 再石灰化 / カテキン / 象牙細管侵入細菌 / 歯髄応答 / 自然免疫 / 病原体特異的分子パターン / パターン認識受容体 / 茶カテキン / 自然免疫機構 / 歯内療法学 / 電磁・高周波 / 骨芽細胞 / 成長因子 / 歯内療法 / マイクロアレイ / オステオポンティン / アドレノメデュリン / 抗菌ペプチド / 診断方法 / 活動期病変 / 線形判別分析 / 歯肉溝浸出液 / 歯肉縁下プラ-ク / 歯肉溝滲出液 / Diagnostic method / Periodontitis / Periodontal disease activity / Linear discriminant analysis / Subgingival plaque / Gingival crevicular fluid / プラーク細菌 / ヒト歯周ポケット / 局在性 / 免疫組織学的検索 / 細菌レクチン / B細胞マイトジェン / 付着因子 / 免疫組織学 / 微細形態学 / Periodontal disease-associated bacteria / Plaque bacteria / Human periodontal pocket / Localization / Immunohistological observation / Bacterial lectin / B cell mitogen / 口腔内細菌 / 根管壁 / 根尖病巣 / 根管拡大 / 根尖部 / 局在 / 歯根部象牙細管 / 侵入 / Infected root canal / Dentinal tubules / Bacteria / Pulpal wall / Periapical lesion / Canal enlargement / う蝕関連細菌 / cyclooxygenase-2 / シクロオキシゲナーゼ-2 / Caries-associated bacteria / Pulpitis / Fibroblast / Cyclooxygenase-2 / 根尖孔外 / 歯根部象牙質 / 免疫組織 / 走査型電子顕微鏡 / 根管治療 / 根尖孔 / apical periodontitis / extra-radical area / bacteria / root dentin / immunohistology / SEM / refractory apical periodontitis / infected root canal treatment / 内皮細胞 / ケモカインレセプター / RT-PCR / ELISA / Streptococcus mutans / IL-1β / TNF-α / CD45RO / macrophage / endothelial cell / lymphocyte / chemokine receptor / サイトカイン / 細菌関連物質 / 細菌由来物質 / 白血球 / cytokine / bacteria-related products / fibroblast / periodontal disease / GST融合蛋白 / histon-like prote / 薬剤耐性遺伝子 / GST fused protein / 歯周病 / 動脈硬化症 / 細菌感染 / 炎症 / 免疫応 / 炎症性サイトカイン / スカベンジャーレセプター / Periodontal Disease / Atherosclerosis / Periodontopathogen / Bacterial Infection / Inflammation / Gene_Expression / Immune Reaction Less
  • Research Projects

    (18 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (18 People)
  •  歯周病変に発現するクローディンとケモカインによる歯周病原因子の上皮透過性制御機構Principal Investigator

    • Principal Investigator
      中江 英明
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  Study of the effects of adrenomedullin upon oral biofilm formation

    • Principal Investigator
      OZAKI Kazumi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Endodontic therapeutic application of electro-magnetic wave irradiation for refractory periapical periodontitis and periapical biofilm

    • Principal Investigator
      YUMOTO Hiromichi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Development of the diagnosis and treatment of root caries on its pathosis and pathogenesis

    • Principal Investigator
      MATSUO Takashi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Study of quorum-sensing system of invading bacteria in dentinal caries

    • Principal Investigator
      OZAKI Kazumi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Clarification of the mechanism of periodontitis-initiated/accelerated atheroacleicsis and identification of its causal components

    • Principal Investigator
      YUMOTO Hiromichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of the mechanisms that claudins expressed in periodontal diseased epithelium regulate the permeability of gingival epitheliumPrincipal Investigator

    • Principal Investigator
      NAKAD Hideaki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of the role of pulp fibroblasts on lymphocytes infiltration in pulpitis

    • Principal Investigator
      FUJINAKA Keiko
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of the genes and proteins that regulate both formation of biofilm and transmission of drug resistance in periodontal disease

    • Principal Investigator
      SHIBUTANI Takuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of gingival epithelial cells and fibroblast using three-dimensional culture system mimic to periodontal pocketsPrincipal Investigator

    • Principal Investigator
      NAKAE Hideaki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  Study on the role of chemokines in the infiltration of inflammatory cells in dental pulp tissue destruction

    • Principal Investigator
      NAKANISHI Tadashi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  A histological investigation into the actual conditions of infected regions of apices of the teeth with apical periodontitis

    • Principal Investigator
      MATSUO Takashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of the relationship between the invasion of dental caries-associated bacteria and the host response of dental pulp in human carious teeth with pulp exposure

    • Principal Investigator
      NAKANISHI Tadashi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima, School of Dentistry
  •  Bacterial Invasion of Infected Canals and Root Dentin of Human Teeth and Analysis of the Host-parasite Interaction at the Apex. - Elucidation of Pathogenesis of Refractory Cases-.

    • Principal Investigator
      MATSUO Takashi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Analysis of the interaction between periodontopathic bacteria and junctional epithelial cells using in situ (RT-) PCRPrincipal Investigator

    • Principal Investigator
      NAKAE Hideaki
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      The University of Tokushima
  •  ヒト歯周炎における炎症浸潤細胞の接着機構の研究

    • Principal Investigator
      MATSUO Takashi
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Conservative dentistry
    • Research Institution
      The University of Tokushima
  •  Localization of periodontal disease-associated bacteria in human periodontal pockets and its relationship to tissue destruction

    • Principal Investigator
      EBISU Shigeyuki
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Tokushima University
  •  Studies on diagnostic methods for measurement of periodontal disease activity

    • Principal Investigator
      EBISU Shigeyuki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      Tokushima University

All 2012 2011 2010 2009 2008 2007 Other

All Journal Article

  • [Journal Article] Interleukin (IL)-17A synergistically enhances CC chemokine ligand 20 production in IL-1 β-stimulated human gingival fibroblast2012

    • Author(s)
      Hosokawa Y, et al
    • Journal Title

      Human Immunology

      Volume: 73 Pages: 26-30

    • DOI

      10.1016/j.humimm.2011.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J08021, KAKENHI-PROJECT-22592122, KAKENHI-PROJECT-23593064, KAKENHI-PROJECT-23792479
  • [Journal Article] Tumor necrosis factor-like weak inducer of apoptosis increases CC chemokine ligand 20 production in interleukin 1β-stimulated human gingival fibroblasts2012

    • Author(s)
      Hosokawa Y, et al.
    • Journal Title

      Human Immunology

      Volume: 73 Pages: 470-473

    • DOI

      10.1016/j.humimm.2012.02.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J08021, KAKENHI-PROJECT-22592122, KAKENHI-PROJECT-23792479
  • [Journal Article] Black tea polyphenol inhibits CXCL10 production in oncostatin M-stimulated human gingival fibroblasts.2011

    • Author(s)
      Hosokawa Y, et al
    • Journal Title

      Int Immunopharmacol

      Volume: 11 Pages: 670-674

    • DOI

      10.1016/j.intimp.2011.01.009

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-09J08021, KAKENHI-PROJECT-22592122, KAKENHI-PROJECT-23390435, KAKENHI-PROJECT-23593064, KAKENHI-PROJECT-23792479
  • [Journal Article] Oncostatin M synergistically induces CXCL10 and ICAM-1 expression in IL-1β-stimulated-human gingival fibroblasts2010

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T
    • Journal Title

      J Cell Biochem

      Volume: 111 Pages: 40-48

    • DOI

      10.1002/jcb.22648

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592122
  • [Journal Article] Proinflammatory effects of muramyldipeptide on human gingival fibroblasts2010

    • Author(s)
      Hosokawa I., Hosokawa Y., Ozaki K., Yumoto H., Nakae H., Matsuo T
    • Journal Title

      J Periodontal Res

      Volume: 45 Pages: 193-199

    • DOI

      10.1111/j.1600-0765.2009.01217.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592122
  • [Journal Article] Tea polyphenols inhibit IL-6 production in tumor necrosis factor superfamily 14-stimulated human gingival fibroblasts2010

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K.Nakanishi T., Nakae H., Matsuo T
    • Journal Title

      Mol Nutr Food Res

      Volume: 54 (Suppl 2)

    • DOI

      10.1002/mnfr.200900549

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592122
  • [Journal Article] TNFSF14 coordinately enhances CXCL10 and CXCL11 productions from IFN-gamma-stimulated human gingival fibroblasts2010

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T
    • Journal Title

      Mol Immunol

      Volume: 47 Pages: 666-670

    • DOI

      10.1016/j.molimm.2009.10.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592122
  • [Journal Article] Catechins inhibit CXCL10 production from oncostatin M-stimulated human gingival fibroblasts2010

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakanishi T., Nakae H., Matsuo T
    • Journal Title

      J Nutr Biochem

      Volume: 21 Pages: 659-664

    • DOI

      10.1016/j.jnutbio.2009.04.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592122
  • [Journal Article] Human gingival fibroblasts express functional chemokine receptor CXCR62009

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T.
    • Journal Title

      Clin Exp Immunol 156

      Pages: 413-418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • [Journal Article] Cytokines differentially regulate CXCL10 production by IFN-gamma or TNF-alpha stimulated-human gingival fibroblasts2009

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T.
    • Journal Title

      J Periodontal Res 44

      Pages: 225-231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • [Journal Article] CC-Chemokine Ligand 17 in periodontal diseases : expression in diseased tissues and production by human gingival fibroblasts2008

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T.
    • Journal Title

      J Periodontal Res 43

      Pages: 471-477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • [Journal Article] Adrenomedullin suppresses tumor necrosis factor alpha-induced CXC chemokine ligand 10 production by human gingival fibroblasts2008

    • Author(s)
      Hosokawa I., Hosokawa Y., Ozaki K., Nakae H., Matsuo T.
    • Journal Title

      Clin Exp Immunol 152

      Pages: 568-575

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • [Journal Article] CXC chemokine ligand 16 in periodontal diseases : expression in diseased tissues and production by cytokine-stimulated human gingival fibroblasts2007

    • Author(s)
      Hosokawa Y., Hosokawa I., Ozaki K., Nakae H., Matsuo T.
    • Journal Title

      Clin Exp Immunol 149

      Pages: 146-154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • [Journal Article] Proinflammatory effects of muramyldipeptide on human gingivaI fibroblasts

    • Author(s)
      Hosokawa I., Hosokawa Y., Ozaki K., Yumoto H., Nakae H., Matsuo T.
    • Journal Title

      J Periodontal Res (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19592204
  • 1.  OZAKI Kazumi (90214121)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 14 results
  • 2.  MATSUO Takashi (30173800)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 1 results
  • 3.  YUMOTO Hiromichi (60284303)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 1 results
  • 4.  NAKANISHI Tadashi (00217770)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 5.  SUGE Toshiyuki (60243713)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  TAKAHASHI Kanako (80403715)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 7.  HOSOKAWA Yoshitaka (90346601)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 8 results
  • 8.  FUJINAKA Keiko (00294710)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  EBISU Shigeyuki (50116000)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  YOSHIYAMA Masahiro (10201071)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  YOSHIDA Yoshiko (20243727)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  KAWASAKI Akiko (60294708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  SHIMIZU Hirotoshi (70294709)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  NOIRI Yuichiro (50218286)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  SHINOHARA Chihiro (50332820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  SHIBUTANI Takuya (20363153)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  URAYAMA Akihisa (40304539)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TAKAMATSU Natsuko (90403716)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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