Toya Yoshiyuki 戸谷義幸

… Alternative Names

TOYA Yoshiyuki 戸谷義幸

Less

Researcher Number	30237143
Other IDs
Affiliation (Current)	2025: 横浜市立大学, 医学研究科, 客員教授
Affiliation (based on the past Project Information) *help	2013 – 2018: 横浜市立大学, 附属病院, 准教授 2006: 横浜市立大学, 大学附属病院, 準教授 2005 – 2006: 横浜市立大学, 附属病院, 準教授 2004: 横浜市立大学, 附属病院, 助教授 2003 – 2004: Yokohama City University, Internal Medicine II, Associated Professer, 医学部附属病院, 助教授 … More 2002 – 2004: 横浜市立大学, 医学部附属病院, 講師 2001: 横浜市立大学, 医学部・附属病院, 講師 1999 – 2000: 横浜市立大学, 医学部, 講師 Less
Review Section/Research Field	Principal Investigator Metabolomics Except Principal Investigator Circulatory organs internal medicine / Biological Sciences / Kidney internal medicine / Metabolomics / Functional biochemistry / General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator gene transfer / type 2 diabetes / glycogen / caveolin / insulin resistance / インスリン / 遺伝子治療 / ノックアウトマウス / 糖尿病 / グリコーゲン … More / カベオリン / インスリン抵抗性 / phosphatase / insulin receptor / insulin / 遺伝子導入 / インスリン感受性 / チロシンフォスファターゼ / インスリン受容体 / knockout mouse / skeletal muscle / insulin signal / 骨格筋 / インスリン刺激伝達系 … More Except Principal Investigator レニン・アンジオテンシン系 / アデニル酸シクラーゼ / カベオリン / eNOS / 動脈硬化 / ACE / cAMP / ノックアウト / インシュリン / カルシウム / 褐色細胞腫 / ニコチン受容体 / 増殖シグナル / 腎臓内科学 / 人工透析学 / アフェレーシス / 脂質異常症 / 閉塞性動脈硬化症 / Nephrin / Renin-angiotensin system / Nephropathy / Diabetes / ネフリン / 腎症 / 糖尿病 / ahterosclerosis / renin-angiotensin system / caveolin / 血管内皮 / レニンアンジオテンシン系 / カベリオン / NOS / 血管平滑筋 / ACE inhibitor / nitric oxide / angiotensin I / angiotensin II / angiotensin (1-7) / 前腕抵抗血管 / 一酸化窒素 / アンジオテンシン(1-7) / 本態性高血圧 / アンジオテンシン変換酵素 / アンジオテンシンII / ブラジキニン / ACE阻害素 / 一酸化窒素(NO) / アンジオテンシンI / アンジオランシンII / アンジオテンシン1-7 / sucrose gradient centrifugation / G protein / transgenic mice / cardiac subtype / subtype / catecholamine / adenylyl cyclase / 分子生物学 / ショ糖密度勾配遠心法 / G蛋白 / 遺伝子操作動物 / 心臓型 / サブタイプ / CAMP / カテコラミン / 生体分子 / トランスレーショナルリサーチ / 循環器・高血圧 / 生理活性 / シグナル伝達 / 受容体 Less

LDL cholesterol apheresis treatment for arteriosclerosis without hypercholesterolemia
- Principal Investigator
  
  Masato Ohsawa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Yokohama City University
Receptor-based modulation of cardiovascular disease in the process of aging
- Principal Investigator
  
  KANAOKA Tomohiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Yokohama City University
The gene transfer of caveolin improves metabolism in diabetic micePrincipal Investigator
- Principal Investigator
  
  TOYA Yoshiyuki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yokohama City University
がん細胞の増殖とカベオリン
- Principal Investigator
  
  石川義弘
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Regulatory roles of podocyte slit membrane associated molecules in cell polarity in diabetes nephropathy
- Principal Investigator
  
  UMEMURA Satoshi, 木原実
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yokohama City University
がん細胞の増殖とカベオリン
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
The lack of caveolin-3, muscle-specific subtype of caveolin, leeds to the development of insulin resistancePrincipal Investigator
- Principal Investigator
  
  TOYA Yoshiyuki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Yokohama City University
The role of caveolin in pathogenesis of arteriosclerosis
- Principal Investigator
  
  KIHARA Minoru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University
SIGNIFICANCE OF THE MULTIPLICITY OF ADENYLYL CYCLASE
- Principal Investigator
  
  ISHIKAWA Yoshihiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Functional biochemistry
- Research Institution
  YOKOHAMACITY UNIVERSITY SCHOOL OF MEDICINE
Vascular effects of angiotensin (1-7) and its contribution to the effect of the cardiovascular drugs
- Principal Investigator
  
  UEDA Shinichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Yokohama City University

All 2017 2015 2014 2013 2006 2004 Other

All Journal Article Presentation

[Journal Article] ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice2017
- Author(s)
  Wakui H, Ohki K, Azushima K, Uneda K, Haku S, Kobayashi R, Haruhara K, Kinguchi S, Matsuda M, Ohsawa M, Maeda A, Minegishi S, Ishigami T, Toya Y, Yamashita A, Umemura S, Tamura K
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 3 Pages: 676-676
- DOI
  10.3390/ijms18030676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19536, KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-15K09293, KAKENHI-PROJECT-16K19558
[Journal Article] Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin2017
- Author(s)
  Uneda Kazushi、Wakui Hiromichi、Maeda Akinobu、Azushima Kengo、Kobayashi Ryu、Haku Sona、Ohki Kohji、Haruhara Kotaro、Kinguchi Sho、Matsuda Miyuki、Ohsawa Masato、Minegishi Shintaro、Ishigami Tomoaki、Toya Yoshiyuki、Atobe Yoshitoshi、Yamashita Akio、Umemura Satoshi、Tamura Kouichi
- Journal Title
  
  Journal of the American Heart Association
  
  Volume: 6 Issue: 8
- DOI
  10.1161/jaha.117.006120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09647, KAKENHI-PROJECT-17K09313, KAKENHI-PROJECT-17K19665, KAKENHI-PUBLICLY-17H05671, KAKENHI-PROJECT-15H04331, KAKENHI-PROJECT-17H06993, KAKENHI-PROJECT-15K09293
[Journal Article] Effects of the oriental herbal medicine Bofu-tsusho-san in obesity hypertension: a multicenter, randomized, parallel-group controlled trial.2015
- Author(s)
  Azushima K, Tamura K, Haku S, Wakui H, Kanaoka T, Ohsawa M, Uneda K, Kobayashi R, Ohki K, Dejima T, Maeda A, Hashimoto T, Oshikawa J, Kobayashi Y, Nomura K, Azushima C, Takeshita Y, Fujino R, Uchida K, Shibuya K, Ando D, Tokita Y, Fujikawa T, Toya Y, Umemura S.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 240 Issue: 1 Pages: 297-304
- DOI
  10.1016/j.atherosclerosis.2015.01.025
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09293, KAKENHI-PROJECT-26893218, KAKENHI-PROJECT-25460906
[Journal Article] Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia.2015
- Author(s)
  Ohsawa M, Tamura K, Wakui H, Kanaoka T, Azushima K, Uneda K, Haku S, Kobayashi R, Ohki K, Haruhara K, Kinguchi S, Toya Y, Umemura S.
- Journal Title
  
  Lipids Health Dis.
  
  Volume: 14 Issue: 1 Pages: 161-161
- DOI
  10.1186/s12944-015-0164-5
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09293, KAKENHI-PROJECT-15K19536, KAKENHI-PROJECT-25460906
[Journal Article] Effects of single pill-based combination therapy of amlodipine and atorvastatin on within-visit blood pressure variability and parameters of renal and vascular function in hypertensive patients with chronic kidney disease.2014
- Author(s)
  Azushima K, Uneda K, Tamura K, Wakui H, Ohsawa M, Kobayashi R, Dejima T, Kanaoka T, Maeda A, Toya Y, Umemura S.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2014 Pages: 437087-437087
- DOI
  10.1155/2014/437087
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-25460906
[Journal Article] Angiotensin receptor-binding protein ATRAP/Agtrap inhibits metabolic dysfunction with visceral obesity.2013
- Author(s)
  Maeda A, Tamura K, Wakui H, Dejima T, Ohsawa M, Azushima K, Kanaoka T, Uneda K, Matsuda M, Yamashita A, Miyazaki N, Yatsu K, Hirawa N, Toya Y, Umemura S.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 2(4) Issue: 4
- DOI
  10.1161/jaha.113.000312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-25460906
[Journal Article] Addition of aliskiren to Angiotensin receptor blocker improves ambulatory blood pressure profile and cardiorenal function better than addition of benazepril in chronic kidney disease2013
- Author(s)
  Ohsawa M, Wakui H, et al
- Journal Title
  
  Int J Mol Sci
  
  Volume: 14(8) Issue: 8 Pages: 15361-75
- DOI
  10.3390/ijms140815361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906
[Journal Article] Umemura S.L/N-type calcium channel blocker cilnidipine added to renin-angiotensin inhibition improves ambulatory blood pressure profile and suppresses cardiac hypertrophy in hypertension with chronic kidney disease2013
- Author(s)
  Kanaoka T, Tamura K, Wakui H, Ohsawa M, Azushima K, Uneda K, Kobayashi R, Fujikawa T, Tsurumi-Ikeya Y, Maeda A, Yanagi M, Toya Y
- Journal Title
  
  Int J Mol Sci
  
  Volume: 14 Issue: 8 Pages: 16866-16881
- DOI
  10.3390/ijms140816866
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906
[Journal Article] Deletion of the angiotensin II type 1 receptor-associated protein enhances renal sodium reabsorption and exacerbates angiotensin II-mediated hypertension.2013
- Author(s)
  Ohsawa M, Tamura K, Wakui H, Maeda A, Dejima T, Kanaoka T, Azushima K, Uneda K, Tsurumi-Ikeya Y, Kobayashi R, Matsuda M, Uchida S, Toya Y, Kobori H, Nishiyama A, Yamashita A, Ishikawa Y, Umemura S.
- Journal Title
  
  Kidney Int.
  
  Volume: 86(3) Issue: 3 Pages: 570-81
- DOI
  10.1038/ki.2014.95
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PLANNED-22136009, KAKENHI-PROJECT-24390200, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906, KAKENHI-PROJECT-25670131
[Journal Article] Bofu-tsu-shosan, an oriental herbal medicine, exerts a combinatorial favorable metabolic modulation including antihypertensive effect on a mouse model of human metabolic disorders with visceral obesity.2013
- Author(s)
  Azushima K, Tamura K, Wakui H, Maeda A, Ohsawa M, Uneda K, Kobayashi R, Kanaoka T, Dejima T, Fujikawa T, Yamashita A, Toya Y, Umemura S.
- Journal Title
  
  PLoS One.
  
  Volume: 8(10) Issue: 10 Pages: e75560-e75560
- DOI
  10.1371/journal.pone.0075560
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23687025, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-25460906
[Journal Article] Upstream stimulatory factors 1 and 2 mediate the transcription of angiotensin II binding and inhibitory protein.2013
- Author(s)
  Matsuda M, Tamura K, Wakui H, Maeda A, Ohsawa M, Kanaoka T, Azushima K, Uneda K, Haku S, Tsurumi-Ikeya Y, Toya Y, Maeshima Y, Yamashita A, Umemura S.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288(26) Issue: 26 Pages: 19238-49
- DOI
  10.1074/jbc.m113.451054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21115004, KAKENHI-PROJECT-23591193, KAKENHI-PROJECT-24591233, KAKENHI-PROJECT-24790950, KAKENHI-PROJECT-24890189, KAKENHI-PROJECT-25460906
[Journal Article] Interacting molecule of AT1 receptor, ATRAP, is colocalized with AT1 receptor in the mouse renal tubules2006
- Author(s)
  Thurumi Y, Toya Y et al.
- Journal Title
  
  Kidney International 69
  
  Pages: 488-494
- Data Source
  KAKENHI-PROJECT-17590943
[Journal Article] Apelin stimulates myosin light chain phosphorylation in vascular smooth muscle cells2006
- Author(s)
  Hashimoto T, Toya Y et al.
- Journal Title
  
  Arterioscler Thromb Vase Biol 26(掲載予定(電子版に掲載中))
  
  Pages: 1267-1272
- Data Source
  KAKENHI-PROJECT-17590943
[Journal Article] Insulin resistance in skeletal muscles of caveolin-3-null mice2004
- Author(s)
  Oshikawa, Jin, Otsu, Koji, Toya, Yoshiyuki, Tsunematsu, Takashi, Hankins, Raleigh, Kawabe, Jun-ichi, Minamisawa, Susumu, Umemura, Satoshi, Hagiwara Yasuko, Ishikawa, Yoshihiro
- Journal Title
  
  Proc Natl Acad Sci USA vol.101 no.34
  
  Pages: 12670-12675
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590951
[Presentation] CKDにおける24時間自由行動下血圧測定(ABPM)による血圧・心拍関連指標と腎機能障害増悪との関連についての研究2013
- Author(s)
  金岡知彦，田村功一，藤川哲也，戸谷義幸，梅村　敏
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-25460906
[Presentation] ENHANCEMENT OF ANGIOTENSIN II TYPE 1 RECEPTOR ASSOCIATED PROTEIN SUPPRESSES VASCULAR REMODELING AND OXIDATIVE STRESS IN ANGIOTENSIN II-MEDIATED HYPERTENSION.
- Author(s)
  Wakui H, Tamura K, Kobayashi R, Uneda K, Azushima K, Ohsawa M, Dejima T, Tsurumi-Ikeya Y, Kanaoka T, Maeda A, Ishigami T, Hirawa N, Toya Y, Yabana M, Umemura S.
- Organizer
  The Joint Meeting of the European Society of Hypertension (ESH, 24th) and International Society of Hypertension (ISH, 25th)
- Place of Presentation
  Athens, Greece
- Year and Date
  2014-06-13 – 2014-06-16
- Data Source
  KAKENHI-PROJECT-25460906
[Presentation] Single Pill-Based Combination Therapy with Amlodipine and Atorvastatin Improves Renal and Vascular Function and Clinic Blood Pressure Variability in Hypertension with Chronic Kidney Disease.
- Author(s)
  Tamura K, Azushima K, Uneda K, Wakui H, Ohsawa M, Kobayashi R, Ohki K, Azuma K, Dejima T, Kanaoka T, Toya Y, Umemura S.
- Organizer
  American Society of Nephrology (ASN) Kidney Week 2014
- Place of Presentation
  Atlanta, USA
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25460906

1. ISHIKAWA Yoshihiro (40305470)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. UMEMURA Satoshi (00128589)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TAMURA Kouichi (40285143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
4. KIHARA Minoru (60177904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 南沢享 (40257332)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KANAOKA Tomohiko (70551258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. GOSHIMA Yoshiro (00153750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KITAMURA Hitoshi (20094302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDA Shinichiro (80285105)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. GOTO Eiji (30153753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HASHIMOTO Tatsuo (20363806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Masato Ohsawa (60733433)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 岩坪耕策 (90363796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 堀英明 (30117759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 常松尚志 (70347300)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 涌井広道 (10587330)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. IKEYA Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 山下暁朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Toya Yoshiyuki 戸谷 義幸

TOYA Yoshiyuki 戸谷 義幸

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The gene transfer of caveolin improves metabolism in diabetic micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The lack of caveolin-3, muscle-specific subtype of caveolin, leeds to the development of insulin resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ATRAP Expression in Brown Adipose Tissue Does Not Influence the Development of Diet-Induced Metabolic Disorders in Mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Angiotensin II Type 1 Receptor‐Associated Protein Regulates Kidney Aging and Lifespan Independent of Angiotensin2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of the oriental herbal medicine Bofu-tsusho-san in obesity hypertension: a multicenter, randomized, parallel-group controlled trial.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of pitavastatin add-on therapy on chronic kidney disease with albuminuria and dyslipidemia.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of single pill-based combination therapy of amlodipine and atorvastatin on within-visit blood pressure variability and parameters of renal and vascular function in hypertensive patients with chronic kidney disease.2014

Author(s)

Journal Title

Toya Yoshiyuki 戸谷義幸

TOYA Yoshiyuki 戸谷義幸