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MITSUI Hiroshi  光井 洋

ORCIDConnect your ORCID iD *help
… Alternative Names

荒井 洋  アライ ヒロシ

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Researcher Number 30239280
Affiliation (based on the past Project Information) *help 2002 – 2006: The University of Tokyo, University Hospital, Research Associate, The University of Tokyo Faculty of Medicine, Research
2001: The University of Tokyo, Graduate School of Medicine, Assistant Professor, 大学院・医学系研究科, 助手
1997 – 2001: 東京大学, 医学部・附属病院, 助手
1997: 東京大学, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Gastroenterology / Gastroenterology
Except Principal Investigator
Gastroenterology
Keywords
Principal Investigator
HCV / liver cancer / RNA interference / 肝臓癌 / RNA干渉 / receptor / 受容体 / liver endothelial cells / Angiostain / 腫瘍血管 … More / 肝臓内皮細胞 / アンギオスタチン / viral receptor / hepatitis C virus / レセプター / C型肝炎 / ウイルスレセプター / C型肝炎ウイルス / 肝細胞 / P38 / Junキナーゼ / トロンビン … More
Except Principal Investigator
cytokine / mutation / HBV-DNA / transgenic mouse / tolerance / HBV / immune suppression therapy / 免疫応答 / HCV / 核酸変異 / 抗原提示 / トランスジェニックマウス / fulminant hepatitis / IFNγ / IL1 / TNFα / 塩基配列 / HBVキャリアー / 免疫抑制剤 / 劇症肝炎 / fulminant hepatits / coagulation & fibrinolysis / plasminogen / hepatocellular carcinoma / angiostatin / 血液凝固線溶系 / プラスミノーゲン / 肝細胞癌 / アンギオスタチン / mouse / prognostic ralue / IgG subtype / interferon / vaccine / peptide / ペプタイト / C型肝炎 / IgGサブクラス / エペトープ / マウス / 治療効果 / IgGサブタイプ / インターフェロン / ワクチン / ペプタイド Less
  • Research Projects

    (9 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (9 People)
  •  Fundamental study for therapy of liver cancers based on RNA interferencePrincipal Investigator

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Identification and analysis of co-receptor for hepatitis C virusPrincipal Investigator

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The comparison of virus genome and immune reaction between asymptomatic carriers and chronic hepatitis patients infected with HBV.

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The study of tumor vessel growth inhibiton Angiostatin, new mechanism of action and clinical applicationPrincipal Investigator

    • Principal Investigator
      MITSUI Hiroshi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Identification of hepatitis C virus receptor on human hepatocytes and regulation of the viral infectionPrincipal Investigator

    • Principal Investigator
      MITUSI Hiroshi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  The mechanism which causes fulminant hepatic failure after immune suppression therapy on HBV carrier patients

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Characterization of the anti-angiogenic factors in hepatocellular carcinoma10301102

    • Principal Investigator
      MAEKAWA Hisato
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  肝細胞の増殖と癌化におけるトロンビンの新たな役割の解明Principal Investigator

    • Principal Investigator
      光井 洋
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo
  •  Investigation for the development of vaccine against hepatitis C virus

    • Principal Investigator
      MARUYAMA Toshiyuki
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      The University of Tokyo

All 2006 2005 2003 2001 Other

All Journal Article

  • [Journal Article] Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound2006

    • Author(s)
      Hanajiri K, Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology Research 36

      Pages: 308-314

    • NAID

      10018639873

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui M, et al.
    • Journal Title

      European Radiology 14

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a microbuble agent to increase the effects of high intensity focused ultrasound on time tissue2005

    • Author(s)
      Kaneko Y, Maruyama T, … Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, et al.
    • Journal Title

      J Gastroenterol 40

      Pages: 1005-1006

    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a minobuble agent to increase the effect of high in tensity focused ultrasound on liver tissuce.2005

    • Author(s)
      Kanaeko Y, Maruyama T, Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui M, et al.
    • Journal Title

      European Radiology 15

      Pages: 1415-1420

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus.2005

    • Author(s)
      Hanajiri K, Mitsui H, Maruyama T, et al.
    • Journal Title

      Journal of Gastroenterology 40

      Pages: 1005-1006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Use of a microbuble agent to increase the effect of high intensity focused ultrasound on liver tissue.2005

    • Author(s)
      Kaneko Y, Maruyama T,... Mitsui H, et al.
    • Journal Title

      Eur Radiol 92

      Pages: 55-62

    • Data Source
      KAKENHI-PROJECT-17590617
  • [Journal Article] Anti-Hβs antibodies produces after liver transplantation : from the donor or the recipient ?2003

    • Author(s)
      Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology 38

      Pages: 271-272

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003

    • Author(s)
      Mitsui H, Maruyama T, et al.
    • Journal Title

      Lancet 361

      Pages: 1993-1993

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003

    • Author(s)
      Mitsui H, … Maruyama T, et al.
    • Journal Title

      Lancet 361

      Pages: 1993-1993

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Anti-HBS antibodies produced after live transplantation : from the donor or the recipient?2003

    • Author(s)
      Maruyama T, Mitsui H, et al.
    • Journal Title

      Hepatology 38

      Pages: 271-272

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590623
  • [Journal Article] Esophageal smooth muscle tumor in a 25-year-old woman with congenital malformations.2001

    • Author(s)
      Maekawa H, Tanaka N, Hashimoto N, Yamada H, Mitsui H, Ikeda H, Maruyama T, Mori M, Nagawa H, Kimura S.
    • Journal Title

      J Gastroenterol. 36(10)

      Pages: 700-703

    • NAID

      50000970489

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] IgGi anti-P2 as a marker of response to interferon in patients with chronic hepatitis C.2001

    • Author(s)
      Hirayama M, Maruyama T, Mitsui H, Maekawa H, Yamada H, Hashimoto N, Koike K, Kimura S, Yasuda K, Iino S, Green J.
    • Journal Title

      Clin Exp Immunol. 126(1)

      Pages: 92-100

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells.2001

    • Author(s)
      Mitsui H, Takuwa N, Maruyama T, Maekawa H, Hirayama M, Sawatari T, Hashimoto N, Takuwa Y, Kimura S.
    • Journal Title

      Int J Cancer. 92(1)

      Pages: 55-62

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] The MEK-ERK MAP Kinase pathuay and the P13-Kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver caneor celle2001

    • Author(s)
      Mitsui H., et al.
    • Journal Title

      Int J Cancer 92

      Pages: 55-62

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-13670496
  • [Journal Article] Use of a microbulluasent to increare the effects of high intensity tocured ultrasound on liver tissue

    • Author(s)
      Kaneko Y, Maruyama T, Mitsui H, et al.
    • Journal Title

      European Ladiology (in press)

    • Data Source
      KAKENHI-PROJECT-15590623
  • 1.  MARUYAMA Toshiyuki (30219571)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 16 results
  • 2.  KOIKE Kazuhiko (80240703)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  MAEKAWA Hisato (10301102)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  SAKATA Youichi (40129028)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YOTSUYANAGI Hiroshi (30251234)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  TSUKAMOTO Kazuhisa (20251233)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TOMA Shigeto (50207528)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  AOKI Katsunori (40291322)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORIYA Kyouji (00272550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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