MITSUI Hiroshi 光井洋

… Alternative Names

荒井洋アライヒロシ

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Researcher Number	30239280
Affiliation (based on the past Project Information) *help	2002 – 2006: The University of Tokyo, University Hospital, Research Associate, The University of Tokyo Faculty of Medicine, Research 2001: The University of Tokyo, Graduate School of Medicine, Assistant Professor, 大学院・医学系研究科, 助手 1997 – 2001: 東京大学, 医学部・附属病院, 助手 1997: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Gastroenterology / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator HCV / liver cancer / RNA interference / 肝臓癌 / RNA干渉 / receptor / 受容体 / liver endothelial cells / Angiostain / 腫瘍血管 … More / 肝臓内皮細胞 / アンギオスタチン / viral receptor / hepatitis C virus / レセプター / C型肝炎 / ウイルスレセプター / C型肝炎ウイルス / 肝細胞 / P38 / Junキナーゼ / トロンビン … More Except Principal Investigator cytokine / mutation / HBV-DNA / transgenic mouse / tolerance / HBV / immune suppression therapy / 免疫応答 / HCV / 核酸変異 / 抗原提示 / トランスジェニックマウス / fulminant hepatitis / IFNγ / IL1 / TNFα / 塩基配列 / HBVキャリアー / 免疫抑制剤 / 劇症肝炎 / fulminant hepatits / coagulation & fibrinolysis / plasminogen / hepatocellular carcinoma / angiostatin / 血液凝固線溶系 / プラスミノーゲン / 肝細胞癌 / アンギオスタチン / mouse / prognostic ralue / IgG subtype / interferon / vaccine / peptide / ペプタイト / C型肝炎 / IgGサブクラス / エペトープ / マウス / 治療効果 / IgGサブタイプ / インターフェロン / ワクチン / ペプタイド Less

Fundamental study for therapy of liver cancers based on RNA interferencePrincipal Investigator
- Principal Investigator
  
  MITSUI Hiroshi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Identification and analysis of co-receptor for hepatitis C virusPrincipal Investigator
- Principal Investigator
  
  MITSUI Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
The comparison of virus genome and immune reaction between asymptomatic carriers and chronic hepatitis patients infected with HBV.
- Principal Investigator
  
  MARUYAMA Toshiyuki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
The study of tumor vessel growth inhibiton Angiostatin, new mechanism of action and clinical applicationPrincipal Investigator
- Principal Investigator
  
  MITSUI Hiroshi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Identification of hepatitis C virus receptor on human hepatocytes and regulation of the viral infectionPrincipal Investigator
- Principal Investigator
  
  MITUSI Hiroshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
The mechanism which causes fulminant hepatic failure after immune suppression therapy on HBV carrier patients
- Principal Investigator
  
  MARUYAMA Toshiyuki
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Characterization of the anti-angiogenic factors in hepatocellular carcinoma10301102
- Principal Investigator
  
  MAEKAWA Hisato
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
肝細胞の増殖と癌化におけるトロンビンの新たな役割の解明Principal Investigator
- Principal Investigator
  
  光井洋
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
Investigation for the development of vaccine against hepatitis C virus
- Principal Investigator
  
  MARUYAMA Toshiyuki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2006 2005 2003 2001 Other

All Journal Article

[Journal Article] Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound2006
- Author(s)
  Hanajiri K, Maruyama T, Mitsui H, et al.
- Journal Title
  
  Hepatology Research 36
  
  Pages: 308-314
- NAID
  10018639873
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005
- Author(s)
  Kaneko Y, Maruyama T, Mitsui M, et al.
- Journal Title
  
  European Radiology 14
  
  Pages: 1415-1420
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] Use of a microbuble agent to increase the effects of high intensity focused ultrasound on time tissue2005
- Author(s)
  Kaneko Y, Maruyama T, … Mitsui H, et al.
- Journal Title
  
  Eur Radiol 92
  
  Pages: 55-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus2005
- Author(s)
  Hanajiri K, Mitsui H, Maruyama T, et al.
- Journal Title
  
  J Gastroenterol 40
  
  Pages: 1005-1006
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] Use of a minobuble agent to increase the effect of high in tensity focused ultrasound on liver tissuce.2005
- Author(s)
  Kanaeko Y, Maruyama T, Mitsui H, et al.
- Journal Title
  
  Eur Radiol 92
  
  Pages: 55-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005
- Author(s)
  Kaneko Y, Maruyama T, Mitsui M, et al.
- Journal Title
  
  European Radiology 15
  
  Pages: 1415-1420
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus.2005
- Author(s)
  Hanajiri K, Mitsui H, Maruyama T, et al.
- Journal Title
  
  Journal of Gastroenterology 40
  
  Pages: 1005-1006
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] Use of a microbuble agent to increase the effect of high intensity focused ultrasound on liver tissue.2005
- Author(s)
  Kaneko Y, Maruyama T,... Mitsui H, et al.
- Journal Title
  
  Eur Radiol 92
  
  Pages: 55-62
- Data Source
  KAKENHI-PROJECT-17590617
[Journal Article] Anti-Hβs antibodies produces after liver transplantation : from the donor or the recipient ?2003
- Author(s)
  Maruyama T, Mitsui H, et al.
- Journal Title
  
  Hepatology 38
  
  Pages: 271-272
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003
- Author(s)
  Mitsui H, Maruyama T, et al.
- Journal Title
  
  Lancet 361
  
  Pages: 1993-1993
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] Clinical efficacy and toxicity of gefitinib in patients with lung cancer2003
- Author(s)
  Mitsui H, … Maruyama T, et al.
- Journal Title
  
  Lancet 361
  
  Pages: 1993-1993
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] Anti-HBS antibodies produced after live transplantation : from the donor or the recipient?2003
- Author(s)
  Maruyama T, Mitsui H, et al.
- Journal Title
  
  Hepatology 38
  
  Pages: 271-272
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590623
[Journal Article] Esophageal smooth muscle tumor in a 25-year-old woman with congenital malformations.2001
- Author(s)
  Maekawa H, Tanaka N, Hashimoto N, Yamada H, Mitsui H, Ikeda H, Maruyama T, Mori M, Nagawa H, Kimura S.
- Journal Title
  
  J Gastroenterol. 36(10)
  
  Pages: 700-703
- NAID
  50000970489
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670496
[Journal Article] IgGi anti-P2 as a marker of response to interferon in patients with chronic hepatitis C.2001
- Author(s)
  Hirayama M, Maruyama T, Mitsui H, Maekawa H, Yamada H, Hashimoto N, Koike K, Kimura S, Yasuda K, Iino S, Green J.
- Journal Title
  
  Clin Exp Immunol. 126(1)
  
  Pages: 92-100
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670496
[Journal Article] The MEK1-ERK map kinase pathway and the PI 3-kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver cancer cells.2001
- Author(s)
  Mitsui H, Takuwa N, Maruyama T, Maekawa H, Hirayama M, Sawatari T, Hashimoto N, Takuwa Y, Kimura S.
- Journal Title
  
  Int J Cancer. 92(1)
  
  Pages: 55-62
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13670496
[Journal Article] The MEK-ERK MAP Kinase pathuay and the P13-Kinase-Akt pathway independently mediate anti-apoptotic signals in HepG2 liver caneor celle2001
- Author(s)
  Mitsui H., et al.
- Journal Title
  
  Int J Cancer 92
  
  Pages: 55-62
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13670496
[Journal Article] Use of a microbulluasent to increare the effects of high intensity tocured ultrasound on liver tissue
- Author(s)
  Kaneko Y, Maruyama T, Mitsui H, et al.
- Journal Title
  
  European Ladiology (in press)
- Data Source
  KAKENHI-PROJECT-15590623

1. MARUYAMA Toshiyuki (30219571)

# of Collaborated Projects: 8 results

# of Collaborated Products: 16 results
2. KOIKE Kazuhiko (80240703)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. MAEKAWA Hisato (10301102)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SAKATA Youichi (40129028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. YOTSUYANAGI Hiroshi (30251234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUKAMOTO Kazuhisa (20251233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TOMA Shigeto (50207528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AOKI Katsunori (40291322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORIYA Kyouji (00272550)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MITSUI Hiroshi 光井 洋

荒井 洋 アライ ヒロシ

Research Projects

Research Products

Co-Researchers

Fundamental study for therapy of liver cancers based on RNA interferencePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification and analysis of co-receptor for hepatitis C virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The comparison of virus genome and immune reaction between asymptomatic carriers and chronic hepatitis patients infected with HBV.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of tumor vessel growth inhibiton Angiostatin, new mechanism of action and clinical applicationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of hepatitis C virus receptor on human hepatocytes and regulation of the viral infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism which causes fulminant hepatic failure after immune suppression therapy on HBV carrier patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of the anti-angiogenic factors in hepatocellular carcinoma10301102

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

肝細胞の増殖と癌化におけるトロンビンの新たな役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation for the development of vaccine against hepatitis C virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound2006

Author(s)

Journal Title

NAID

Description

Data Source

[Journal Article] Use of a microbubble agent to increase the effects of high intensity focused ultrasound on liver tissue.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Use of a microbuble agent to increase the effects of high intensity focused ultrasound on time tissue2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] 18F-FDG PET for hepatocellular carcinoma presenting with portal vein tumor thrombus2005

Author(s)

Journal Title

Data Source

[Journal Article] Use of a minobuble agent to increase the effect of high in tensity focused ultrasound on liver tissuce.2005

MITSUI Hiroshi 光井洋

荒井洋アライヒロシ