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Otsuka Masato  大塚 正人

ORCIDConnect your ORCID iD *help
… Alternative Names

大塚 正人  オオツカ マサト

OOTSUKA Masato  大塚 正人

OTSUKA Masato  大塚 正人

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Researcher Number 30243489
Other IDs
External Links
Affiliation (Current) 2025: 摂南大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 摂南大学, 薬学部, 教授
2012 – 2013: 摂南大学, 薬学部, 教授
2007 – 2011: Okayama University, Advanced Science Research Center, Associate Professor
2006: 岡山大学, 自然生命科学研究支援センター, 助教授
2005: Okayama University, Advanced Science Research Center, 自然生命科学支援センター, 助手 … More
2003 – 2005: 岡山大学, 自然生命科学研究支援センター, 助手
2004: 岡山大学, 大学院・自然科学研究科, 助手
2004: Okayama university, Advanced Science Research Center, Research Associate, 自然生命科学研究支援センターゲノムプロテオーム解析部門, 助手
2000 – 2002: 岡山大学, 薬学部, 助手
1996 – 1997: 岡山大学, 薬学部, 助手
1992 – 1993: 岡山大学, 薬学部, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Functional biochemistry / Biological Sciences / Structural biochemistry
Except Principal Investigator
Biological pharmacy / Biological pharmacy / Biological Sciences / Functional biochemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry / Functional biochemistry
Keywords
Principal Investigator
Transporter / MATE / Multidrug / kidney / organic cation transporter / Multidrug transporter / organic cation / Kidney / 薬物副作用軽減 / 有機カチオン … More / 輸送体 / 薬物排出 / 生化学 / Organic cation transport / 膜タンパク質 / Topology / Membrane protein / Glutamate / トランスポーター / トポロジー / グルタミン酸 / transpoter / トランスポートソーム / multidrug / Organic cation exchange / プロトン交換輸送系 / 薬物輸送 / 多剤耐性 / 大量発現 / センサーロドプシン … More
Except Principal Investigator
glutamate / glutathione / GABA / melatonin / グルタミン酸 / 松果体 / 概日リズム / メラトニン / cysteine / yeast / sbp gene / cysA gene / sulfate permease / Cl^--ATPase / シナプス小胞 / 共役イオン / トポロジー / 神経科学 / トランスポーター / シグナル伝達 / VGLUT / 小胞輸送 / グルタチオン / メチルグリオキサール / タコ / 軟体動物 / 脱水素酵素 / D-乳酸 / シメチジン / 阻害剤 / 多剤排出ポンプ / MATE1 / pinal gland / disulfide bonde / circadian rhythm / redox regulation / serotonin N-acetyltransferase / ジスルフィド結合 / レドックス制御 / メラトニン合成酵素 / vesicular GABA transporter / vesicular glutamate transporter / islet of Langerhans / A cell / B cell / グルタミン酸トランスポーター / 血糖 / 小胞型グルタミン酸トランスポーター / 糖尿病 / 小胞型GABAトランスポーター / ランゲルハンス氏島 / α細胞 / β細胞 / serotonin / serotonin-N-acetyltransferase(NAT) / aspartate / receptor / pineabcyte / circadyan rhythm / Dアスパラギン酸 / 結晶化 / N-actyltranferase / 小胞型グルタミン酸輸送体 / 松果体細胞 / マイクロベジクル / セロトニン / serotonin-N acetyltransferase (NAT) / アスパラギン酸 / 受容体 / cystathionine b-synthetase / g-glutamylcysteine synthetase / hepatotoxicity / acetoaminophen / S- (12 -dicarboxyethyl) glutathione / Ca結合蛋白質 / 視細胞 / リン酸化 / Pγ Kinase / Pγ / HPLC / 蛍光誘導体 / 生体防御 / 活性酸素 / 酸化型グルタチオン / 還元型グルタチオン / cystathionine β-synthetase / γ glutamylcysteine synthetase / 肝障害 / アセトアミノフェン / S-(1,2-dicarboxyethyl)glutathione / Acetabularia acetabulum / ABC type ATPase / F type ATPase / cloning / 遺伝子クローニング / 一次性能動輸送系 / アニオン / Cl^-ATPase / カサノリ / ABCタイプATPase / FタイプATPase / クローニング / イン・シリコ / インシリコ / 構造活性相関 / オートドッキング / 酵素阻害 / 抗腫瘍 / ステロイド / デアザフラビン / フラビン / リポソーム / リン脂質 / PS / エキサイトーシス / フリップフロップ / ATPase / オクトピン / イカ / トレオニン / ウズラ / 寄生生物 / 食胞 / brefeld in A / 抗マラリア薬 / NSF / V-ATPase / マラリア原虫 / オピン類 / 乳酸脱水素酵素 / 鳥類 / 1,2-プロパンジオール / スレオニン / グリオキサラーゼ / ギ酸 / 1,2-プロパン・ジオール / 前癌状態 / メチル・グリオキサール Less
  • Research Projects

    (19 results)
  • Research Products

    (106 results)
  • Co-Researchers

    (24 People)
  •  多剤耐性菌のMATE型多剤排出ポンプを選択的に阻害するリード化合物の創出

    • Principal Investigator
      表 雅章
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
    • Research Institution
      Setsunan University
  •  The structure and function of new drug excreting transporter MATE in mannmalPrincipal Investigator

    • Principal Investigator
      OTSUKA Masato
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Setsunan University
      Okayama University
  •  The structure and function of new drug excreting transporter "MATE" in mannmal.Principal Investigator

    • Principal Investigator
      OOTSUKA Masato
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  Molecular design and enzyme inhibition mode using software supported by computer for antitumor active flavin derivatives

    • Principal Investigator
      NAGAMATSU Tomohisa
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Drug development chemistry
    • Research Institution
      Okayama University
  •  薬物排出の最終段階を担う新規有機カチオン輸送体の構造と機能及び相互作用Principal Investigator

    • Principal Investigator
      大塚 正人
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  The structure and function analysis of MATE transporter in Mammal.Principal Investigator

    • Principal Investigator
      OTSUKA Masato
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  小胞型グルタミン酸トランスポーターのシナプス小胞へのターゲッティング機構

    • Principal Investigator
      森山 芳則
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  フォスファチジルセリン輸送性ATPaseの作動機構と開口放出における意義

    • Principal Investigator
      森山 芳則
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Okayama University
  •  The redox regulation of melatonin synthesis in circadian rhythm

    • Principal Investigator
      TSUBOI Seiji
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      SHUJITSU UNIVERSITY
  •  シナプス小胞型グルタミン酸輸送体の構造・機能と生理的意義

    • Principal Investigator
      森山 芳則
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Okayama University
  •  Molecular mechanism of L-glutamate and GABA-mediated regulation of secretion of glucagon and insulin in islets of Langerhans

    • Principal Investigator
      MORIYAMA Yoshinori
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  Structure and function of synaptic vesicle transporter which supports glutamstergic chemical transduction.Principal Investigator

    • Principal Investigator
      OTUKA Masato
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  ハロバクテリアのセンサーロドプシンIIの3次元構造Principal Investigator

    • Principal Investigator
      大塚 正人
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Okayama University
  •  マラリア原虫の寄生性を支える分子的基盤に関する研究

    • Principal Investigator
      MORIYAMA Yoshinori
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Okayama University
  •  鳥類や軟体動物における新しいD―乳酸の生成と代謝経路

    • Principal Investigator
      大森 晋爾
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Tsuyama National College of Technology
  •  Molecular mechanisms of regulation of melatonin synthesis in pineal gland

    • Principal Investigator
      MORIYAMA Yoshinori
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      OKAYAMA UNIVERSITY
  •  D-乳酸を含む新しいエネルギー獲得経路とその生理的意義

    • Principal Investigator
      OHMORI Shinji
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Functional biochemistry
    • Research Institution
      Tsuyama National College of Technology
      Okayama University
  •  Regulation on new regulation in photoreceptor signal transduction

    • Principal Investigator
      TSUBOI Seiji
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      Okayama University
  •  Studies on active anion transport systems in a biological membrane

    • Principal Investigator
      OHMORI Shinji
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Okayama University

All 2024 2023 2022 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

  • [Journal Article] Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria2024

    • Author(s)
      Susumu Shinya, Kentaro Kawai, Naoki Kobayashi, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masato Otsuka, Masaaki Omote
    • Journal Title

      Bioorg. Med. Chem.

      Volume: 99 Pages: 117606-117606

    • DOI

      10.1016/j.bmc.2024.117606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06514, KAKENHI-PROJECT-23K06125, KAKENHI-PROJECT-20K07059
  • [Journal Article] Fluorophenylalkyl-substituted cyanoguanidine derivatives as bacteria-selective MATE transporter inhibitors for the treatment of antibiotic-resistant infections2022

    • Author(s)
      Susumu Shinya, Kentaro Kawai, Naoki Kobayashi, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masato Otsuka, Masaaki Omote
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 74 Pages: 117042-117042

    • DOI

      10.1016/j.bmc.2022.117042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07059, KAKENHI-PROJECT-22K06514
  • [Journal Article] Goda H MATE1 and associated protein in human kidney2014

    • Author(s)
      Otsuka M.
    • Journal Title

      Arch. Biochem. Biophys.

    • Data Source
      KAKENHI-PROJECT-23570168
  • [Journal Article] MATE1 and associated proteins in human kidney cells2014

    • Author(s)
      Otsuka M, Goda H
    • Journal Title

      Arch. Biochem. Biophys.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Journal Article] Synthesis of BMS-309403-Related Compounds, Including [14C]BMS-309403, a Radioligand for Adipocyte Fatty Acid Binding Protein2012

    • Author(s)
      Toshihiko Okada, Makoto Hiromura, Masato Otsuka, Shuichi Enomoto, Hiroyuki Miyachi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 60 Issue: 1 Pages: 164-168

    • DOI

      10.1248/cpb.60.164

    • NAID

      130001852342

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Journal Article] Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter.2011

    • Author(s)
      Otsuka M, Komatsu T, Hiasa M, Kanamoto T, Matsumoto T, Moriyama Y, Omote H.
    • Journal Title

      Int J Biochem Cell Biol. 43(6)

      Pages: 913-918

    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Characterization of the human MATE2 proton-coupled polyspecific organic cation exporter.2011

    • Author(s)
      Otsuka M, Komatsu T, Hiasa M, Kanamoto T, Matsumoto T, Moriyama Y, Omote H.
    • Journal Title

      Int J Biochem Cell Biol.

      Volume: 43(6) Pages: 913-918

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Identification of a vesicular nucleotide transporter.2009

    • Author(s)
      Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.
    • Journal Title

      Proc Natl Acad Sci USA(National Academy of Sciences) Vol.105, No.15

      Pages: 5683-5686

    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Identification of a vesicular nucleotide transporter.2009

    • Author(s)
      Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.
    • Journal Title

      Proc Natl Acad Sri USA. 105

      Pages: 5683-5686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Role of glutamate residues in substrate recognition by human MATEl polyspecilic H+/organic cation exporter.2008

    • Author(s)
      Matsumoto T, Kanamoto T, Otsuka M, Omote H, Moriyama Y.
    • Journal Title

      Am J Physiol Cell Physiol. 294

      Pages: 10741078-10741078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] Identification of a vesicular nucleotide transporter.2008

    • Author(s)
      Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.
    • Journal Title

      Proc Natl Acad Sci USA. (Epub ahead of print)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] Role of glutamate residues in substrate recognition by human MATE1 polyspecific H+/organic cation exporter.2008

    • Author(s)
      Matsumoto T, Kanamoto T, Otsuka M, Omote H, Moriyama Y.
    • Journal Title

      Am J Physiol Cell Physiol. 294

      Pages: 1074-1078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] Role of glutamate residues in substrate recognition by human MATEl polyspecific H+/organic cation exporter2008

    • Author(s)
      Matsumoto T, Kanamoto T, Otsuka M, Omote H, Moriyama Y.
    • Journal Title

      Am J Physiol Cell Physiol. 294(4)

      Pages: 1074-1078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Identification of a vesicular nucleotide transporter.2008

    • Author(s)
      Sawada K, Echigo N, Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.
    • Journal Title

      Proc Nafl Acad Sci USA (Epub ahead of print)

    • NAID

      120002306983

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] Identification of a vesicular nucleotide transporter.2008

    • Author(s)
      Sawada K, Echigo N. Juge N, Miyaji T, Otsuka M, Omote H, Yamamoto A, Moriyama Y.
    • Journal Title

      Proc Natl Acad Sci U S A. 105(15)

      Pages: 5683-5686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] A novel variant of mouse MATE-1 H+/organic cation antiporter with a long hydrophobic tail.2008

    • Author(s)
      Kobara A, Hiasa M, Matsumoto T, Otsuka M, Omote H, Moriyama Y.
    • Journal Title

      Arch Biochem Biophys. 469

      Pages: 195-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] A novel variant of mouse MATE-1 H+/organic cation antiporter with a long hydrophobic tail.2008

    • Author(s)
      Kobara A, Hiasa M, Matsumoto T, Otsuka M, Omote H, Moriyama Y.
    • Journal Title

      Arch Biocfiem Biophys. 469

      Pages: 195199-195199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] A novel variant of mouse MATE-1 H+/organic cation antiporter with a long hydrophobic tail.2008

    • Author(s)
      Kobara A. Hiasa M, Matsumoto T, Otsuka M. Omote H. Moriyama Y.
    • Journal Title

      Arch Biochem Biophys 469(2)

      Pages: 195-199

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Journal Article] Transmembranc Topology of Vesicular Glutamate Transporter 22006

    • Author(s)
      Jung SK, Morimoto R, Otsuka M, Omote H.
    • Journal Title

      Biol. Pham. Bull. 29(3)

      Pages: 547-549

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Transmembrane topology of vesicular glutamate transporter 2.2006

    • Author(s)
      Jung SK, Morimoto R, Otsuka M, Omote H.
    • Journal Title

      Biol Pharm Bull. 29(3)

      Pages: 547-9

    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K., Ishimura, A., Otsuka, M., Yamamoto, A., Maechler, P., Moriyama, Y.
    • Journal Title

      J.Neurochem. 96

      Pages: 550-560

    • Data Source
      KAKENHI-PROJECT-16044232
  • [Journal Article] The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.2006

    • Author(s)
      Omote H, Hiasa M, Matsumoto T, Otsuka M, Moriyama Y.
    • Journal Title

      Trends Pharmacol Sci. 27(11)

      Pages: 587-93

    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara S, Jung SK, Morimoto R, Arioka S, Miyaji T, Juge N, Hiasa M, Shimizu K, Ishimura A, Otsuka M, Yamamoto A, Maechler P, Moriyama Y
    • Journal Title

      J.Neurochem. 96(2)

      Pages: 550-560

    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara S, Jung SK, Morimoto R, Arioka S, Miyaji T, Juge N, Hiasa M, Shimizu K, Ishimura A, Otsuka M, Yamamoto A, Maechler P, Moriyama Y
    • Journal Title

      J. Neurochem. 96(2)

      Pages: 550-60

    • Data Source
      KAKENHI-PROJECT-18590057
  • [Journal Article] Transmembrane Topology of Vesicular Glutamate Transporter 22006

    • Author(s)
      Jung, S.K., Morimoto, R., Otsuka, M., Omote, H.
    • Journal Title

      Biol.Pharm.Bull.Mar 29(3)

      Pages: 547-549

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara S, Jun S.K, Morimoto R, Arioka S, Miyaji T, Juge N, Hiasa M, Ishimura A, Otsuka M, Yamamoto A, Maechler P, Moriyama Y.
    • Journal Title

      J Neurochem. 96(2)

      Pages: 550-560

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K., Ishimura, A., Otsuka, M., Yamamoto, A., Maechler, P., Moriyama, Y.
    • Journal Title

      J.Neurochem. 96

      Pages: 550-560

    • Data Source
      KAKENHI-PROJECT-16657038
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K., Ishimura, A., Otsuka, M., Yamamoto, A., Maechler, P., Moriyama, Y.
    • Journal Title

      J.Neurochem. 96

      Pages: 550-560

    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] The MATE proteins as fundamental transporters of metabolic and xenobiotic organic cations.2006

    • Author(s)
      Omote H, Hiasa M, Matsumoto T, Otsuka M, Moriyama Y
    • Journal Title

      Trends Pharmacol Sci. 27(11)

      Pages: 587-593

    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] A human transporter protein that mediates the final excretion step for toxic organic cation2006

    • Author(s)
      Otsuka M, Matsumoto T, Morimoto R, Arioka S, Omote H, Moriyama Y
    • Journal Title

      Proc. Natl. Acad Sci. USA. 02(50)

      Pages: 17923-17928

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara, S., Jung, S.K., Morimoto, R., Arioka.S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K., Ishimura, A., Otsuka, M., Yamamoto, A., Maechler, P., Moriyama Y.
    • Journal Title

      J. Neurochem. 96

      Pages: 550-560

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Transmembrane topology of vesicular glutamate transporter 2.2006

    • Author(s)
      Jung SK, Morimoto R, Otsuka M, Omote H
    • Journal Title

      Biol Pharm Bull. 29(3)

      Pages: 547-549

    • NAID

      110005602141

    • Data Source
      KAKENHI-PROJECT-18059023
  • [Journal Article] Vesicular storage and secretion of L-glutamate from glucagon-like peptide 1-secreting clonal intestinal L cells.2006

    • Author(s)
      Uehara, S., Jung, S.K., Morimoto, R., Arioka, S., Miyaji, T., Juge, N., Hiasa, M., Shimizu, K., Ishimura, A., Otsuka, Yamamoto, A., Maechler, P., Moriyama, Y.
    • Journal Title

      J.Neurochem. 96

      Pages: 550-560

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Identification of essential amino acid residues of the NorM Na^+/multidrug antiporter in Vibrio parahaemolyticus.2005

    • Author(s)
      Otsuka, M., Yasuda, M., Morita, Y., Otsuka, C., Tsuchiya, T., Omote, H., Moriyama, Y.
    • Journal Title

      J.Bacteriol. 187

      Pages: 1552-1558

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Identification of essential amino acid residues of the NorM Na+/multidrug antiporter in Vibrio parahaemolyticus.2005

    • Author(s)
      Otsuka M, Yasuda M, Morita Y, Otsuka C, Tsuchiya T, Omote H, Moriyama Y.
    • Journal Title

      J Bacteriol.

      Pages: 1552-1558

    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] A human transpoter protein that mediates the final excretion step for toxic organic cations.2005

    • Author(s)
      Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., Moriyama, Y.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 17923-17928

    • Data Source
      KAKENHI-PROJECT-16657038
  • [Journal Article] A human transpoter protein that mediates the final excretion step for toxic organic cations.2005

    • Author(s)
      Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., Moriyama, Y.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 17923-17928

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] A human transpoter protein that mediates the final excretion step toxic organic cations.2005

    • Author(s)
      Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., Moriyama, Y.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 17923-17928

    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Identification of essential amino acid residues of the NorM Na+/multidrug antiporter in Vibrio parahaemolyticus2005

    • Author(s)
      Otsuka M, Yasuda M, Morita Y, Otsuka C, Tsuchiya T, Omote H, Moriyama Y.
    • Journal Title

      J Bacteriol.

      Pages: 1552-1558

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Identification of essential amino acid residues of the NorM Na^+/multidrug antiporter in Vibrio parahaemolyticus.2005

    • Author(s)
      Otsuka, M., Yasuda, M., Morita, Y., Otsuka, C., Tsuchiya, T., Omote.H., Moriyama, Y.
    • Journal Title

      J. Bacteriol. 187

      Pages: 1552-1558

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] A human transpoter protein that mediates the final excretion step for toxic organic cations.2005

    • Author(s)
      Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., Moriyama, Y.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 17923-17928

    • Data Source
      KAKENHI-PROJECT-16044232
  • [Journal Article] A human transpoter protein that mediates the final excretion step for toxic organic cations.2005

    • Author(s)
      Otsuka, M., Matsumoto, T., Morimoto, R., Arioka, S., Omote, H., Moriyama, Y.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 17923-17928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] From the Cover : A human transporter protein that mediates the final excretion step for toxic organic cation.2005

    • Author(s)
      Otsuka M, Matsumoto T, Morimoto R, Arioka S, Omote H, Moriyama Y
    • Journal Title

      Proc.Natl.Acad.Sci. U S A. 02(50)

      Pages: 17923-17928

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Identification of essential amino acid residues of the NorMNa^+/multidrug antiporter in Vibrio parahaemolyticus.2005

    • Author(s)
      Otsuka, M., Yasuda, M., Morita, Y., Otsuka, C., Tsuchiya, T., Omote, H., Moriyama.Y.
    • Journal Title

      J.Bacteriol. 187

      Pages: 1552-1558

    • Data Source
      KAKENHI-PROJECT-16657038
  • [Journal Article] Identification of essential amino acid residues of the NorMNa^+/multidrug antiporter in Vibrio parahaemolyticus.2005

    • Author(s)
      Otsuka, M., Yasuda, M., Morita, Y., Otsuka, C., Tsuchiya, T., Omote, H., Moriyama, Y.
    • Journal Title

      J.Bacteriol. 187

      Pages: 1552-1558

    • Data Source
      KAKENHI-PROJECT-16044232
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by α cells of islet of Langerhans.2004

    • Author(s)
      Uehara, S., Muroyama, A., Echigo, N., Morimoto, R., Otsuka, M., Yatsushiro, S., Moriyama, Y.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by a cells of islet of Langerhans.2004

    • Author(s)
      Uehara, S., Muroyama, A., Echigo, N., Morimoto, R., Otsuka, M., Yatsushiro, S., Moriyama, Y.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in autoinhibitory cascade for glucagon secretion by alpha-cells of islet of Langerhans2004

    • Author(s)
      Uehara S, Muroyama A, Echigo N, Morimoto R, Otsuka M, Yatsushiro S, Moriyama Y
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by α cells of islet of Langerhans.2004

    • Author(s)
      Uehara, S., Muroyama, A., Echigo, N., Morimoto, R., Otsuka, M., Yatsushiro, S., Moriyma, Y.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Metabotropic Glutamate Receptor Type 4 is Involved in Auto-inhibitory Cascade for Glucagon Secretion by □ Cells of Islet of Langerhans.2004

    • Author(s)
      S.Uehara, A.Muroyama, N.Echigo, R.Morimoto, M.Otsuka, S.Yatsushiro, Y.Moriyama.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by α cells of islet of Langerhans.2004

    • Author(s)
      Uehara, S., Muroyama, A., Echigo, N., Morimoto, R., Otsuka, M., Yatsushiro, S., Moriyama, Y.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Data Source
      KAKENHI-PROJECT-16657038
  • [Journal Article] Metabotropic glutamate receptor type 4 is involved in auto-inhibitory cascade for glucagon secretion by α cells of islet of Langerhans.2004

    • Author(s)
      Uehara, S., Muroyama, A., Echigo, N., Morimoto, R., Otsuka, M., Yatsushiro, S., Moriyama, Y.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Data Source
      KAKENHI-PROJECT-16044232
  • [Journal Article] Metabotropic Glutamate Receptor Type 4 is Involved in Auto-inhibitory Cascade for Glucagon by a Cells of Islet Langerhans2004

    • Author(s)
      S.Uehara, A.Muroyama, N.Echigo, R.Morimoto, M.Otsuka, S.Yatsushiro, Y.Moriyama.
    • Journal Title

      Diabetes 53

      Pages: 998-1006

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in alphaTC6 cells, mouse clonal alpha-cells, and alpha-cells of islets of Langerhans.2003

    • Author(s)
      Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y
    • Journal Title

      Diabetes 52

      Pages: 2066-2074

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules inalphaTC6 cells, mouse clonal alpha-cells, alpha-cells of islets of Langerhans.2003

    • Author(s)
      Hayashi M, Otsuka M, Morimoto R, Muroyama A, Uehara S, Yamamoto A, Moriyama Y.
    • Journal Title

      Diabetes. 52

      Pages: 2066-2074

    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in α TC6 cells, mouse clonal α cells, and α cells of islets of Langerhans.2003

    • Author(s)
      Hayashi, M., Otsuka, M., Morimoto, R., Muroyama, A., Uehara, S., Yamamoto, A., Moriyama, Y.
    • Journal Title

      Diabetes 52

      Pages: 2066-2074

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Vesicular inhibitory amino acid transporter is present in glucagon-containing secretory granules in αTC6 cells, mouse clonal α cells, and α cells of islets of Langerhans.2003

    • Author(s)
      M.Hayashi, M.Otsuka, R.Morimoto, A.Muroyama, S.Uehara, A.Yamamoto, Y.Moriyama
    • Journal Title

      Diabetes 52

      Pages: 2066-2074

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390026
  • [Journal Article] Co-expression of vesicular glutamate transporters (VGLUT1 and VGLUT2) and their association with synaptic-like microvesicles in rat pinealocytes.2003

    • Author(s)
      Morimoto R, Hayashi M, Yatsushiro S, Otsuka M, Yamamoto A, Moriyama Y
    • Journal Title

      J Neurochem 84

      Pages: 382-391

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590060
  • [Journal Article] Co-expression of vesicular glutamate transporters (VGLUT1 and VGLUT2) and their association with synaptic-like microvesicles in rat pinealocytes.2003

    • Author(s)
      Morimoto, R., Hayashi, M., Yatsushiro, S., Otsuka, M., Yamamoto, A., Moriyama, Y.
    • Journal Title

      J Neurochem. 84(2)

      Pages: 382-391

    • Data Source
      KAKENHI-PROJECT-15590060
  • [Presentation] 細菌抗菌薬排出機構MATE型輸送体の新規阻害剤の探索合成と活性評価2023

    • Author(s)
      新屋 進, 河合 健太郎, 小林 直木, 軽尾 友紀子, 樽井 敦, 佐藤 和之, 大塚 正人, 表 雅章
    • Organizer
      第46回フッ素化学討論会
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] 細菌MATE型薬剤排出ポンプ阻害剤の探索合成と活性評価2023

    • Author(s)
      新屋 進、河合健太郎、小林直木、軽尾友紀子、樽井 敦、佐藤和之、大塚正人、表 雅章
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] Development of Selective Inhibitors Targeting Multi-antimicrobial extrusion transporter to Overcome Antibiotic Resistance2023

    • Author(s)
      Susumu Shinya, Kentaro Kawai, Naoki Kobayashi, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Masato Otsuka, Masaaki Omote
    • Organizer
      23rd International Symposium on Fluorine Chemistry (ISFC) and the 9th International Symposium on Fluorous Technologies (ISoFT)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] Exploration and Synthesis of Inhibitors Targeting the Bacterial Multidrug Efflux Pump MATE-type transporter2023

    • Author(s)
      新屋 進, 河合 健太郎, 小林 直木, 軽尾 友紀子, 樽井 敦, 佐藤 和之, 大塚 正人, 表 雅章
    • Organizer
      第40回メディシナルケミストリーシンポジウム
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] 多剤耐性菌に有効な細菌選択的MATE型輸送体阻害剤の創生2022

    • Author(s)
      新屋 進, 河合健太郎, 小林直木, 軽尾友紀子, 樽井 敦, 佐藤和之, 大塚正人, 表 雅章
    • Organizer
      第42回有機合成若手セミナー
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] 多剤耐性菌に有効な細菌選択的MATE 型輸送体阻害剤(SS-322)の創生2022

    • Author(s)
      新屋 進, 河合健太郎, 小林直木, 軽尾友紀子, 樽井 敦, 佐藤和之, 大塚正人, 表 雅章
    • Organizer
      創薬懇話会 2022 in名古屋
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] 細菌多剤排出輸送体MATE阻害化合物の探索合成と活性評価2022

    • Author(s)
      新屋 進、河合健太郎、小林直木、軽尾友紀子、樽井 敦、佐藤和之、大塚正人、表 雅章
    • Organizer
      日本薬学会関西支部大会
    • Data Source
      KAKENHI-PROJECT-22K06514
  • [Presentation] 骨格筋におけるMATE1の分布と生理的機能の解析2014

    • Author(s)
      合田  光 寛 、 反 田  宗 良、大塚 正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学・熊本
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] MATE型輸送体のトランスポートソームに関する組織化学的検討2014

    • Author(s)
      笹谷美砂音, 松原邦晃, 合田光寛, 大塚正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] ホモロジーモデリング法を用いたMATE1の輸送に関与するアミノ酸残基に迫る2014

    • Author(s)
      森謙人, 合田光寛, 大塚正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 有機カチオン輸送体hMATE1を含むトランスポートソームの解析2014

    • Author(s)
      石 塚 弘司、合田  光 寛、大塚 正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学・熊本
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] NSAIDs排泄機能をもつTETRANの機能解析 TETRAN2014

    • Author(s)
      信田 悠衣、合田  光 寛、大塚 正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学・熊本
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 有機カチオン輸送体11MATEIを含むトランスポートソームの解析2014

    • Author(s)
      石塚弘司, 合田光寛, 大塚正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] NSAIDs排泄機能をもつTETRAN'の機能解析2014

    • Author(s)
      信田悠衣, 合田光寛, 大塚正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] MATE型輸送体のトランスポートソームに関する組織化学的検討2014

    • Author(s)
      笹 谷 美 砂 音 、 松 原  邦 晃 、 合田  光 寛 、大塚 正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学・熊本
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 骨格筋におけるMATEIの分布と生理的機能の解析2014

    • Author(s)
      合田光寛, 反田宗良, 大塚正人
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Year and Date
      2014-03-28
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] MATE型輸送体のトランスポートソームに関する免疫組織化学的検討2013

    • Author(s)
      松原邦晃、笹谷美砂音、合田光寛、大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜・横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 骨格筋におけるhMATE1の分布及び機能解析2013

    • Author(s)
      反田宗良、大壁和輝、合田光寛、大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜・横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] MATE型輸送体のトランスポートソームに関する免疫組織化学的検討2013

    • Author(s)
      笹谷美砂音, 松原邦晃, 合田光寛, 大塚正人
    • Organizer
      第63回日本薬学会近畿支部総会大会京都
    • Year and Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 人有機アニオン輸送体Tetracycline transporter-like protein(TETRAN)の構造と機能の解析2013

    • Author(s)
      澁谷紗恵子, 信田悠衣, 合田光寛, 大塚正
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-59 MATE 型輸送体のトランスポートソームに関する免疫組織化学的検討2013

    • Author(s)
      笹谷美砂音、松原邦晃、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] ホモロジーモデリング法を用いて、hMATE1の輸送に関与するアミノ酸残基に迫る!!!2013

    • Author(s)
      鈴木裕士、森 謙人、合田光寛、大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜・横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 人骨格筋におけるhMATE1の分布及び機能解析2013

    • Author(s)
      反田宗良, 大壁和輝, 合田光寛, 大塚正
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] ホモロジーモデリング法を用いて、hMATE1の輸送に関与するアミノ酸残基に迫る!!!2013

    • Author(s)
      鈴木裕士, 森謙人, 合田光寛, 大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-64 多剤排泄トランスポーターhMATE1 のホルモン輸送への関与2013

    • Author(s)
      小田果奈、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 有機アニオン輸送体 Tetracycline transporter-like protein (TETRAN)の構造と機能の解析2013

    • Author(s)
      澁谷紗恵子、信田悠衣、合田光寛、大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜・横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 新規有機カチオン輸送体 hMATE1 を含むトランスポートソームの解析2013

    • Author(s)
      齋藤武尊、石塚弘司、合田光寛、大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜・横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-62 ホモロジーモデリング法を用いた hMATE1の輸送に関与するアミノ酸残基の特定2013

    • Author(s)
      森 謙人、鈴木裕士、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 新規有機カチオン輸送体hMATE1を含むトランスポートソームの解析2013

    • Author(s)
      齋藤武尊, 石塚弘司, 合田光寛, 大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 有機アニオン輸送体Tetracycline transporter-like protein(TETRAN)の機能解析2013

    • Author(s)
      信田悠衣, 澁谷紗恵子, 合田光寛, 大塚正人
    • Organizer
      第63回日本薬学会近畿支部総会大会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 骨格筋におけるMATE1の分布と生理的機能の解析2013

    • Author(s)
      大壁和輝, 反田宗良, 合田光寛, 大塚正人
    • Organizer
      第63回日本薬学会近畿支部総会大会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-60 新規有機カチオン輸送体 hMATE1 を含むトランスポートソームの解析2013

    • Author(s)
      石塚弘司、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-63 骨格筋における MATE1 の分布と生理的機能の解析2013

    • Author(s)
      大壁和輝、反田宗良、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] MATE型輸送体のトランスポートソームに関する免疫組織化学的検討2013

    • Author(s)
      松原邦晃, 笹谷美砂音, 合田光寛, 大塚正人
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] ホモロジーモデリング法を用いたhMATE1の輸送に関与するアミノ酸残基の特定2013

    • Author(s)
      森謙人, 鈴木裕士, 合田光寛, 大塚正人
    • Organizer
      第63回日本薬学会近畿支部総会大会
    • Place of Presentation
      京都
    • Year and Date
      2013-10-12
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] P2-61 有機アニオン輸送体 Tetracycline transporter-like protein (TETRAN) の機能解析2013

    • Author(s)
      信田悠衣、澁谷紗恵子、合田光寛、大塚正人
    • Organizer
      第63回 日本薬学会近畿支部総会・大会
    • Place of Presentation
      同志社女子大学・京都
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] 新規有機カチオン輸送体hMATE1のタンパク質相互作用解析2012

    • Author(s)
      大塚正人、合田光寛
    • Organizer
      日本薬学会近畿支部大会
    • Place of Presentation
      武庫川女子大学薬学部
    • Data Source
      KAKENHI-PROJECT-23570168
  • [Presentation] ヒトMATE型のトランスポートソーム解析2011

    • Author(s)
      大塚正人、小田昌幸
    • Organizer
      日本薬学会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] ヒトMATE型のトランスポートソーム解析2010

    • Author(s)
      小田和昌、大塚正人
    • Organizer
      日本薬学会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] 薬物の最終段階を司る新規輸送体について2008

    • Author(s)
      大塚正人
    • Organizer
      膜タンパク質シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-05-14
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] 小胞型グルタミン酸トランスポーター1(VGLUT1)及びVGLUT1Rの機能解析2008

    • Author(s)
      居原田真史、樹下成信、日浅未来、大塚正人、表弘志、森山芳則
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] 小胞型ATPトランスポーターの同定と機能解析2008

    • Author(s)
      澤田啓介、越後典子、樹下成信、宮地孝明、日浅未来、大塚正人、表弘志、森山芳則
    • Organizer
      第30回生体膜と薬物の相互作用シンポジウム,第21回バイオメディカル分析科学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] Molecular characterization of the human MATE2 polyspecific H^+/organic cation exporter.2008

    • Author(s)
      大塚正人、松本拓也、日浅未来、表弘志、森山芳則
    • Organizer
      第81回日本生化学会大会,第31回日本分子生物学会年会,BMB2008
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590059
  • [Presentation] 哺乳動物における新規薬物排出輸送体MATEの構造と機能及び相互作用2007

    • Author(s)
      大塚 正人
    • Organizer
      生体エネルギー研究会 第33回 討論会
    • Place of Presentation
      山口大学
    • Year and Date
      2007-11-15
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Presentation] 哺乳動物における新規薬物排出輸送体財MATEの構造と機能及び相互作用2007

    • Author(s)
      大塚 正人
    • Organizer
      排出トランスポーターから創薬を考える研究会
    • Place of Presentation
      大阪大学
    • Year and Date
      2007-02-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Presentation] The structure and fimction analysis of MATE transporter in Mammal2007

    • Author(s)
      M., Otsuka
    • Organizer
      Multidrug transporter Symposium
    • Place of Presentation
      Osaka
    • Year and Date
      2007-02-09
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590057
  • [Presentation] Role of glutamate residues in substrate recognition by human MATE1 polyspecific H+/organic cation exporter2007

    • Author(s)
      M., Otsuka
    • Organizer
      JBEG
    • Place of Presentation
      Yamaguchi
    • Year and Date
      2007-11-15
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590057
  • 1.  MORIYAMA Yoshinori (10150658)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 20 results
  • 2.  TSUBOI Seiji (50172052)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  OHMORI Shinji (10032872)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  NAGAMATSU Tomohisa (40155966)
    # of Collaborated Projects: 1 results
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  • 5.  MORITANI Chie (60253001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  IKEDA Mikiko (20112154)
    # of Collaborated Projects: 1 results
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  • 7.  YAMADA Hiroshi (80325092)
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  • 8.  YATSUSHIRO Syouki (90399155)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  表 弘志 (10273707)
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  • 10.  表 雅章 (90299032)
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    # of Collaborated Products: 8 results
  • 11.  軽尾 友紀子 (30826235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 12.  河合 健太郎 (60826246)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 13.  SHINDO Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  IKEUCHI Momoe
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  ASHIDA Noriyuki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  LOTTSPEICH Friedrich
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  OESTERHELT Dieter
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  AJAYA Shretha R.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIOZAWA Jud
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SHIOZAWA Judith a.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  JUDITH A. Sh
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  FRIEDRICH Lo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  DIETER Oeste
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  小林 直木
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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