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Honma Masamitsu  本間 正充

… Alternative Names

HONMA Masamitsu  本間 正充

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Researcher Number 30250179
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7805-3290
Affiliation (Current) 2025: 国立医薬品食品衛生研究所, ゲノム安全科学部, 客員研究員
Affiliation (based on the past Project Information) *help 2013 – 2018: 国立医薬品食品衛生研究所, 変異遺伝部, 部長
2011: 国立医薬品食品衛生研究所, 変異遺伝部, 室長
Review Section/Research Field
Principal Investigator
Risk sciences of radiation and chemicals
Except Principal Investigator
Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals
Keywords
Principal Investigator
DNA 修復 / ゲノム編集技術 / BLMヘリケース / 相同組み換え / 遺伝的不安定性 / 発がん / 低線量モデル / 放射線防護 / DNA修復
Except Principal Investigator
ゲノム … More / トランスジェニックマウス遺伝子突然変異試験 / 生殖細胞突然変異 / 次世代シークエンサー / 環境変異原 / 遺伝子突然変異 / 次世代影響 / 遺伝毒性 / 放射線 / 突然変異 / DNA修復 / プロテオーム / 修復 Less
  • Research Projects

    (3 results)
  • Research Products

    (72 results)
  • Co-Researchers

    (11 People)
  •  Construction of a DNA double-strand break model and its application to studies of DNA repair and low dose irradiation effectsPrincipal Investigator

    • Principal Investigator
      Honma Masamitsu
    • Project Period (FY)
      2013 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Studies on quantitative evaluation of inherited germline mutations

    • Principal Investigator
      Masumura Kenichi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      National Institute of Health Sciences
  •  Comprehensive analyses of DNA Topoisomerase I and relating DNA repair

    • Principal Investigator
      HORIBATA Katsuyoshi
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      National Institute of Health Sciences

All 2019 2018 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

  • [Journal Article] Science for Genome Safety2019

    • Author(s)
      Honma Masamitsu
    • Journal Title

      Impact

      Volume: 2019 Issue: 3 Pages: 59-61

    • DOI

      10.21820/23987073.2019.3.59

    • Open Access
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Journal Article] Evaluation of the sensitivity and specificity of in vivo erythrocyte micronucleus and transgenic rodent gene mutation tests to detect rodent carcinogens2016

    • Author(s)
      Morita T , Hamada S, Masumura K, Wakata A, Maniwa J, Takasawa H, Yasunaga K, Hashizume, T, Honma M.
    • Journal Title

      Mutation Research

      Volume: 802 Pages: 1-29

    • DOI

      10.1016/j.mrgentox.2016.03.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Journal Article] Dose-dependent de novo germline mutations detected by whole-exome sequencing in progeny of ENU-treated male gpt delta mice.2016

    • Author(s)
      Masumura K,Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Journal Title

      Mutation Research

      Volume: 810 Pages: 30-39

    • DOI

      10.1016/j.mrgentox.2016.09.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
  • [Journal Article] Estimation of the frequency of inherited germline mutations by whole exome sequencing in ethyl nitrosourea-treated and untreated gpt delta mice.2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Journal Title

      Genes and Environment

      Volume: 38 Issue: 1 Pages: 10-10

    • DOI

      10.1186/s41021-016-0035-y

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-25281027
  • [Journal Article] Sensitivity of human cells expressing low-fidelity or weak-catalytic-activity variants of DNA polymerase ξ to genotoxic stresses2016

    • Author(s)
      T. Suzuki, P. Gruz, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      DNA Repair

      Volume: 45 Pages: 34-43

    • DOI

      10.1016/j.dnarep.2016.06.002

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281029, KAKENHI-PROJECT-25340044
  • [Journal Article] Mutagenic consequences of cytosine alterations site-specifically embedded in the human genome.2016

    • Author(s)
      Sassa A, Kanemaru Y, Kamoshita N, Honma M, Yasui M.
    • Journal Title

      Genes and Environment

      Volume: 38 Issue: 1 Pages: 17-17

    • DOI

      10.1186/s41021-016-0045-9

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-16K16195
  • [Journal Article] Mutator phenotype and DNA double-strand break repair in BLM helicase-deficient human cells.2016

    • Author(s)
      Suzuki T, Yasui M, Honma M
    • Journal Title

      Mol Cell Biol.

      Volume: 36 Issue: 23 Pages: 2877-2889

    • DOI

      10.1128/mcb.00443-16

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-25340044
  • [Journal Article] The role of DNA polymerase zeta in translesion synthesis across bulky DNA adducts and cross-links in human cells2016

    • Author(s)
      T. Suzuki, P. Gruz, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      Mutation Research

      Volume: 791-792 Pages: 35-41

    • DOI

      10.1016/j.mrfmmm.2016.08.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26281029, KAKENHI-PROJECT-25340044
  • [Journal Article] Epigenetic mutagen as histone modulator can be detected by yeast flocculation2016

    • Author(s)
      Sugiyama, K., Furusawa, H., Shimizu, M., Gruz, P. and Honma, M
    • Journal Title

      Mutagenesis

      Volume: 31 Issue: 6 Pages: 687-693

    • DOI

      10.1093/mutage/gew041

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15K00561, KAKENHI-PROJECT-25340044
  • [Journal Article] Genomic integration of lambda EG10 transgene in gpt delta transgenic rodents2015

    • Author(s)
      Masumura K, Sakamoto Y, Kumita W, Honma M, Nishikawa A, Nohmi T.
    • Journal Title

      Genes and Environment

      Volume: 37 Issue: 1 Pages: 24-24

    • DOI

      10.1186/s41021-015-0024-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25281027, KAKENHI-PROJECT-25293034, KAKENHI-PROJECT-26281029
  • [Journal Article] Catalytic and non-catalytic roles of DNA polymerase κ in the protection of human cells against genotoxic stresses2015

    • Author(s)
      Kanemaru Y, Suzuki T, Niimi N, Gruze P, Matsumoto K, Adachi N, Honma M, Nohmi T
    • Journal Title

      Environmental Moleculer Mutagenesis

      Volume: 56 Issue: 8 Pages: 650-662

    • DOI

      10.1002/em.21961

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-26281029
  • [Journal Article] Smarcal1 promotes double-strand-break repair by nonhomologous end-joining2015

    • Author(s)
      Keka IS, Mohiuddin, Maede Y, Rahman MM, Sakuma T, Honma M, Yamamoto T, Takeda S, Sasanuma H
    • Journal Title

      Nucleic Acid Research

      Volume: 13 Issue: 13 Pages: 6259-6372

    • DOI

      10.1093/nar/gkv621

    • NAID

      120005617590

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-23221005
  • [Journal Article] Evaluation of the in vivo genotoxicity of Allura Red AC (Food Red No. 40)2015

    • Author(s)
      Honma M
    • Journal Title

      Food and Chemical Toxicology

      Volume: 84 Pages: 270-275

    • DOI

      10.1016/j.fct.2015.09.007

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Journal Article] Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome2015

    • Author(s)
      Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M
    • Journal Title

      PLOS ONE

      Volume: 10 Issue: 11 Pages: e0142218-e0142218

    • DOI

      10.1371/journal.pone.0142218

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-25281022
  • [Journal Article] Effects of the proposed top concentration limit on an in vitro chromosomal aberration test to assay sensitivity or to reduce the number of false positives.2014

    • Author(s)
      Morita, T., Miyajima, A., Hatano, A., Honma, M
    • Journal Title

      Mutation Research

      Volume: 769 Pages: 34-49

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Journal Article] Tracing the fates of site-specifically introduced DNA adducts in the human genome.2014

    • Author(s)
      Yasui M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T, and Honma M.
    • Journal Title

      DNA Repair

      Volume: 15 Pages: 11-20

    • DOI

      10.1016/j.dnarep.2014.01.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
  • [Journal Article] in vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase2014

    • Author(s)
      A. Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R.C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      DNA Repair

      Volume: 15 Pages: 21-28

    • DOI

      10.1016/j.dnarep.2013.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035, KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
  • [Journal Article] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a]pyrene, and 4-nitroquinoline-1-oxide in the Pig-a and gpt assays2013

    • Author(s)
      K. Horibata, A. Ukai, T. Kimoto, T. Suzuki, N. Kamoshita, K. Masumura, T. Nohmi and M. Honma
    • Journal Title

      Environ. Mol. Mutagen.

      Volume: 54 Issue: 9 Pages: 747-754

    • DOI

      10.1002/em.21818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-25281027
  • [Journal Article] these authors contributed equally to this work. Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair2012

    • Author(s)
      Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shin-ichiro Kanno, Hidetoshi Tahara, Edward G Neilan, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
    • Journal Title

      Nature Genetics

      Volume: 44(5) Pages: 593-597

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Journal Article] Further Development of the Rat Pig-a Mutation Assay : Measuring Rat Pig-a Mutant Bone Marrow Erythroids and a High Throughput Assay for Mutant Peripheral Blood Reticulocytes2011

    • Author(s)
      Takafumi Kimoto, Satsuki Chikura, Kumiko Suzuki, Xiao mei Kobayashi, Yasuhiro Itano, Katsuyoshi Horibata, Masamitsu Honma, Vasily N. Dobrovolsky, Robert H. Heflich, Daishiro Miura and Yoshinori Kasahara
    • Journal Title

      Environmental and Molecular Mutagenesis

      Volume: 52 Pages: 774-783

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Journal Article] Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex2011

    • Author(s)
      Katsuyoshi Horibata, Masafumi Saijo, Mui Nee Bay, Li Lan, Isao Kuraoka, Philip J. Brooks, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
    • Journal Title

      Genes to Cells

      Volume: 16(1) Pages: 101-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Journal Article] Fullerene(C60) is negative in the in vivo Pig-A gene mutation assay2011

    • Author(s)
      Katsuyoshi Horibata, Akiko Ukai, Naoki Koyama, Atsuya Takagi, Jun Kanno, Takafumi Kimoto, Daishiro Miura, Akihiko Hirose, and Masamitsu Honma
    • Journal Title

      Genes and Environment

      Volume: 33(1) Pages: 27-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] A Fate of DNA Double Strand Break in Human Cells Influenced by Exogenous or Endogenous Circumstances2018

    • Author(s)
      Masamitsu Honma
    • Organizer
      42nd Anneual Meeting of Environmental Mutagen Society in India
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] ICH Genotoxicity Guideline2016

    • Author(s)
      Masamitsu Honma
    • Organizer
      Symposium on Genetic Toxicology and Development Toxicology
    • Place of Presentation
      中国・ハイラル
    • Year and Date
      2016-08-27
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] Analysis of inherited germline mutations of ENU-treated mice by whole exome sequencing2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Organizer
      Society of Toxicology 55th Annual meeting
    • Place of Presentation
      New Orleans Ernest N. Morial Convention Center, LA, USA
    • Year and Date
      2016-03-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] 遺伝毒性発がん物質のリスク評価2016

    • Author(s)
      本間 正充
    • Organizer
      第43回日本毒性学会学術年会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] TRACING THE FATES OF SITE-SPECIFICALLY INTRODUCED OXIDATIVE DNA DAMAGE IN THE HUMAN GENOME2016

    • Author(s)
      Honma1 M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T, Yasui
    • Organizer
      14th International Workshop on Radiation Damage to DNA
    • Place of Presentation
      オーストラリア メルボルン
    • Year and Date
      2016-03-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] 何故、今、変異原性in silicoなのか?2016

    • Author(s)
      本間 正充
    • Organizer
      日本環境変異原学会第45回大会
    • Place of Presentation
      つくば
    • Year and Date
      2016-11-17
    • Invited
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] ゲノム上に起きたDNA損傷の運命をターゲットミュータジェネシスにより追跡する2016

    • Author(s)
      本間 正充
    • Organizer
      日本環境変異原学会公開シンポジウム
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] マウス肝発がん物質を用いた遺伝毒性および発がん性の定量的分析に関する研究2016

    • Author(s)
      増村健一,本間正充
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Estimation of the frequency of inherited germline mujtations by whole-exome sequencing in ethylnitrosourea-treated gpt delta mice2016

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ukai A, Gondo Y, Honma M, Nohmi T
    • Organizer
      47th Annual Meeting of Environmental Mutagenesis and Genomics Society
    • Place of Presentation
      Westin Kansas City at Crown center
    • Year and Date
      2016-09-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] AMES/QSAR International Collaborative Study2016

    • Author(s)
      Masamitsu Honma
    • Organizer
      QSAR2016
    • Place of Presentation
      米国・マイアミ
    • Year and Date
      2016-06-13
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] 全エキソーム解析を用いたENU 投与雄マウスの次世代個体における生殖細胞系列突然変異頻度の測定2016

    • Author(s)
      増村健一,鵜飼明子,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第45回大会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスの生殖細胞におけるアクリルアミド誘発突然変異の解析2015

    • Author(s)
      萩尾宗一郎、阿部正義、林清吾、辻菜穂、黒田雄介、古川賢、八木孝司、本間正充、増村健一
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] トランスジェニック動物遺伝子突然変異試験におけるin vivo変異原性と発がん性の相関に関する研究2015

    • Author(s)
      増村健一,森田健,本間正充
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] In vitroおよびin vivo遺伝毒性試験の組合せによる齧歯類発がん物質の検出力2015

    • Author(s)
      森田健、濱田修一、増村健一、本間正充
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Trend and Progress of OECD Genotoxicity Testing Guidelines2015

    • Author(s)
      Honma M
    • Organizer
      39th Annual Meeting of Environmental Mutagen Society of India
    • Place of Presentation
      インド インパール
    • Year and Date
      2015-05-18
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] gpt deltaマウスを用いたアクリルアミドの生殖細胞遺伝子突然変異の解析2015

    • Author(s)
      萩尾宗一郎,小川いづみ,阿部正義,林清吾,辻菜穂,黒田雄介,古川賢,八木孝司,本間正充,増村健一
    • Organizer
      第42回日本毒性学会学術年会
    • Place of Presentation
      石川県立音楽堂
    • Year and Date
      2015-06-29
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Honma M, Ukai A, Hamasaki K, KodamGenome mapping of chromosome regions damaged by ionizing irradiation of human blood T-cells using CGH-microarray analysis2015

    • Author(s)
      Honma M, Ukai A, Hamasaki K, Kodama Y, Noda A, Kusunoki Y
    • Organizer
      15th International Congress of Radiation Research
    • Place of Presentation
      京都
    • Year and Date
      2015-05-26
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] DNA Double Strand Break Repair in BLM Deficient Human Cells.2015

    • Author(s)
      Honma M, Suzuki T
    • Organizer
      46th Annual Meeting of Environmental Mutagenesis and Genomics Society
    • Place of Presentation
      米国 ニューオリンズ
    • Year and Date
      2015-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] マウス全エキソーム解析によるENU誘発生殖細胞変異スペクトルの解析2015

    • Author(s)
      増村健一、鵜飼明子、豊田尚美、権藤洋一、能美健彦、本間正充
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] ICHガイドラインS2(R1)におけるin vivo試験組合せの検討2015

    • Author(s)
      山田雅巳、大杉直弘、髙木久宜、和田邦生、松元郷六、大隅友香、真田尚和、百南綾華、堤絵梨、堀妃佐子、赤沼三恵、増村健一、本間正充
    • Organizer
      日本環境変異原学会第44回大会
    • Place of Presentation
      九州大学馬出キャンパス
    • Year and Date
      2015-11-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaラット肝臓における自然突然変異および加齢に伴う変異蓄積の検討2013

    • Author(s)
      増村健一,豊田尚美,石井雄二,梅村隆志,能美健彦,西川秋佳,本間正充
    • Organizer
      第72回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Spontaneous point mutations and deletions increased with aging in gpt delta transgenic mice and rats2013

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Osugi N, Ishii Y, Umemura T, Takagi H, Nishikawa A, Nohmi T, Honma M
    • Organizer
      11th International Conference on Environmental Mutagens
    • Place of Presentation
      Bourbon Cataratas Convention & Spa Resort, Foz do Iguazu, Brazil
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスを用いたENU誘発突然変異と全エクソンシークエンスによる経世代変異の検出2013

    • Author(s)
      増村健一,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第42回大会
    • Place of Presentation
      岡山コンベンションセンター(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Evaluation of in vivo genotoxicity induced by N-ethyl-N-nitrosourea, benzo[a] pyrene and 4-nitroquinoline-1-oxide by Pig-a and gpt assays2012

    • Author(s)
      Katsuyoshi Horibata, Akiko Ukai, Takafumi Kimoto, Tetsuya Suzuki, Nagisa Kamoshita, Kenichi Masumura, Takehiko Nohmi and Masamitsu Honma
    • Organizer
      Society of Toxicology 51st Annual Meeting
    • Place of Presentation
      San Francisco
    • Year and Date
      2012-03-15
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] glycidolと3-MCPD及びこれらのエステル化合物におけるラット28日間反復投与試験の影響について2012

    • Author(s)
      大波冴子,曹永晩,豊田武士,堀端克良,本間正充,能美健彦,西川秋佳,小川久美子
    • Organizer
      第28回日本毒性病理学会総会
    • Year and Date
      2012-02-03
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Molecular cloning of the gene for UV-Sensitive Syndrome with deficiencies in Transcription-coupled DNA repair2011

    • Author(s)
      Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shinichiro Kanno, Edward G. Neilan, Hidetoshi Tahara, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
    • Organizer
      Conference : Response to DNA damage : from molecular mechanism to human disease
    • Place of Presentation
      Egmond aan Zee, Netherlands
    • Year and Date
      2011-04-04
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Further Development of the Rat Pig-a Mutation assay : Measuring Rat Pig-a Mutant Bone Marrow Erythroids and a High Throughput Assay for Mutant Peripheral Blood Reticulocytes2011

    • Author(s)
      Takafumi Kimoto, Satsuki Chikura, Kumiko Suzuki, Xiao mei Kobayashi, Yasuhiro Itano, Katsuyoshi Horibata, Masamitsu Honma, Vasily N. Dobrovolsky, Robert H. Heflich, Daishiro Miura and Yoshinori Kasahara
    • Organizer
      Environmental Mutagen Society 42nd Annual Meeting
    • Place of Presentation
      Montreal
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] ラット末梢血を用いるPig-aアッセイ共同研究:測定技術の共有化と施設間差に関する研究報告2011

    • Author(s)
      木本崇文,堀端克良,武藤重治,真田尚和,橋本和之,伊東悟,宇野芳文,本間正充
    • Organizer
      日本環境変異原学会第40回大会
    • Year and Date
      2011-11-21
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] A Japanese Collaborative Study on Rat Pig-a Assay ; Report on a Transferability of the Assay Method and Interlaboratory Difference2011

    • Author(s)
      Takafumi Kimoto, Katsuyoshi Horibata, Shigeharu Muto, Hisakazu Sanada, Kazuyuki Hashimoto, Satoru Itoh, Yoshifumi Uno and Masamitsu Honma
    • Organizer
      Environmental Mutagen Society 42nd Annual Meeting
    • Place of Presentation
      Montreal
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] In vitro genotoxicity assay using primary hepatocytes derived from gpt delta transgenic mouse2011

    • Author(s)
      堀端克良,増村健一,能美健彦,本間正充
    • Organizer
      第70回日本癌学会学術総会
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] 新規in vivo遺伝子突然変異評価系(Pig-aアッセイ)の検討:骨髄エリスロイド及び末梢血網状赤血球を用いるPig-aアッセイの開発2011

    • Author(s)
      木本崇文,千藏さつき,鈴木久美子,小林小梅,板野泰弘, Vasily N. Dobrovolsky, Robert H. Heflich,堀端克良,本間正充,三浦大志郎,笠原義典
    • Organizer
      第38回日本トキシコロジー学会学術年会
    • Year and Date
      2011-07-11
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Molecular cloning of the gene for UV-sensitive syndrome with deficiencies in transcription-coupled DNA repair2011

    • Author(s)
      Xue Zhang, Katsuyoshi Horibata, Masafumi Saijo, Chie Ishigami, Akiko Ukai, Shinichiro Kanno, Edward. G Neilan, Hidetoshi Tahara, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
    • Organizer
      第34回日本分子生物学会年会
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Pig-aアッセイとトランスジェニック突然変異試験の組合せに関する研究2011

    • Author(s)
      堀端克良,鵜飼明子,木本崇文,鈴木哲矢,鴨下渚,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第40回大会
    • Year and Date
      2011-11-22
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] In Vitro Genotoxicity Tests Using Primary Hepatocytes2011

    • Author(s)
      Katsuyoshi Horibata, Akiko Ukai, Kenichi Masumura, Takehiko Nohmi and Masamitsu Honma
    • Organizer
      Environmental Mutagen Society 42nd Annual Meeting
    • Place of Presentation
      Montreal
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Evaluation of in vivo genotoxicity of glycidol and 3-MCPD and associated esters, using Pig-A and micronucleus assays2011

    • Author(s)
      大波冴子,曹永晩,豊田武士,堀端克良,本間正充,能美健彦,西川秋佳,小川久美子
    • Organizer
      第70回日本癌学会学術総会
    • Year and Date
      2011-10-05
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] UVSSA and USP7 cooperate to stabilize CSB in transcription-coupled DNA repair2011

    • Author(s)
      Masafumi Saijo, Xue Zhang, Katsuyoshi Horibata, Chie Ishigami, Akiko Ukai, Shin-ichiro Kanno, Hidetoshi Tahara, Edward G. Neilan, Masamitsu Honma, Takehiko Nohmi, Akira Yasui and Kiyoji Tanaka
    • Organizer
      第34回日本分子生物学会年会
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Non-genotoxic effects of low-dose ionizing irradiation on DNA double str and break repair2010

    • Author(s)
      Honma, M., et al.
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] IN VITRO CHROMOSOME ABERRATION AND CELL TRANSFORMATION TESTS ON FULLEREN AND MALTI-WALL CARBON NANOTUBES2010

    • Author(s)
      Honma, M., et al.
    • Organizer
      European Environmental Mutagen Society 40^<th> Annual Meeting
    • Place of Presentation
      Oslo(Norway)
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] DNA2本鎖切断修復に対する低線量放射線等の環境ストレスの影響2010

    • Author(s)
      本間正充,安井学,堀端克良,鈴木哲矢,谷田貝文夫
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] gpt deltaトランスジェニックマウス由来初代培養肝細胞を用いたin vitro遺伝毒性試験2010

    • Author(s)
      堀端克良,鵜飼明子,増村健一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第39回大会
    • Year and Date
      2010-11-16
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] Molecular cloning of the gene for UV-sensitive syndrome with deficiencies in transcription-coupled DNA repair2010

    • Author(s)
      Zhang Xue,石上智愛,堀端克良,鵜飼明子,本間正充,能美健彦,田原英俊,田中亀代次
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] In vivo gene mutation assay using endogenous Pig-A gene2010

    • Author(s)
      堀端克良,鵜飼明子,木本崇文,三浦大志郎,本間正充
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] IN VITRO CHROMOSOME ABERRATION AND CELL TRANSFORMATION TESTS ON FULLEREN AND MALTI-WALL CARBON NANOTUBES2010

    • Author(s)
      Masamitsu Honma, Katsuyoshi Horibata, Toshitaka Takahashi, Shin Asada, Takumi Hara, Yuzuki Nakagawa, Atsuko Ikeda, Kohji Yamakage and Akihiko Hirose
    • Organizer
      40th Meeting of European Environmental Mutagen Society
    • Place of Presentation
      Oslo, Norway
    • Year and Date
      2010-09-16
    • Data Source
      KAKENHI-PROJECT-22710061
  • [Presentation] gpt deltaラットの加齢により誘発される点突然変異および欠失変異の解析

    • Author(s)
      増村健一,豊田尚美,石井雄二,梅村隆志,能美健彦,西川秋佳,本間正充
    • Organizer
      第37回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Tracing the fates of site-specifically introduced DNA adducts in the human genome.

    • Author(s)
      Honma, M., Yasui, M., Kanemaru, Y., Kamoshita, N., Suzuki, T., Arakawa, T.
    • Organizer
      4回アジア環境変異原学会
    • Place of Presentation
      インド、コルカタ
    • Year and Date
      2014-12-10 – 2014-12-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-25340044
  • [Presentation] マウス全エクソンシークエンス解析による経世代突然変異の測定

    • Author(s)
      増村健一,豊田尚美,権藤洋一,能美健彦,本間正充
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      一橋講堂
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスを用いたアクリルアミドの生殖細胞に対する遺伝毒性評価

    • Author(s)
      萩尾宗一郎,小川いづみ,阿部正義,林清吾,辻菜穂,黒田雄介,古川賢,八木孝司,本間正充,増村健一
    • Organizer
      日本環境変異原学会第43回大会
    • Place of Presentation
      一橋講堂
    • Year and Date
      2014-12-04 – 2014-12-05
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] gpt deltaマウスを用いた加齢に伴い蓄積する遺伝子突然変異の解析

    • Author(s)
      増村健一,大杉直弘,豊田尚美,能美健彦,本間正充
    • Organizer
      日本進化学会第16回大会
    • Place of Presentation
      高槻現代劇場
    • Year and Date
      2014-08-21 – 2014-08-24
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Point mutations and deletions induced by aging in liver of gpt delta transgenic rats

    • Author(s)
      Masumura K, Toyoda-Hokaiwado N, Ishii Y, Umemura T, Honma M, Nishikawa A, Nohmi T
    • Organizer
      4th Asian Conference on Environmental Mutagens
    • Place of Presentation
      CSIR-Indian Institute of Chemical Biology, Kolkata, India
    • Year and Date
      2014-12-10 – 2014-12-12
    • Data Source
      KAKENHI-PROJECT-25281027
  • [Presentation] Demonstration of non-threshold of 8-oxoG inducing genotoxicity by targeted mutagenesis.

    • Author(s)
      Honma, M., Yasui, M., Kanemaru, Y., Kamoshita, N., Suzuki, T., Arakawa, T.
    • Organizer
      第43回ヨーロッパ環境変異原学会
    • Place of Presentation
      英国、ランカスター
    • Year and Date
      2014-07-07 – 2014-07-09
    • Data Source
      KAKENHI-PROJECT-25340044
  • 1.  HORIBATA Katsuyoshi (40402995)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 22 results
  • 2.  Masumura Kenichi (40291116)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 3.  NOHMI Takehiko (30150890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 16 results
  • 4.  TOYODA Naomi (70381853)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 5.  Yasui Manabu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 6.  Suzuki Tetsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  Sassa Akira
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  SAJI Tetsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  GRUZ Petr
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  権藤 洋一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  杉山 圭一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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