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TAKANO MASAOKI  鷹野 正興

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Masaoki Takano  鷹野 正興

TAKANO Masaoki  鷹野 正興

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Researcher Number 30258107
Other IDs
Affiliation (Current) 2025: 神戸学院大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2020 – 2024: 神戸学院大学, 薬学部, 教授
2015: 神戸学院大学, 薬学部, 講師
2010: 神戸学院大学, 薬学部, 講師
2005 – 2006: 神戸学院大学, 薬学部, 講師
2001 – 2004: 神戸学院大学, 薬学部, 助手
1997 – 1999: 神戸学院大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 56040:Obstetrics and gynecology-related / Biological pharmacy
Except Principal Investigator
Biological pharmacy / Neuroscience in general / Medical pharmacy / Biological pharmacy / Neuroscience in general
Keywords
Principal Investigator
β-CG / Rimklb / 雄性不妊 / リン酸化S6タンパク質 / リボソームタンパク質S6 / Leydig細胞 / mTOR / 乏精子症 / 血液-精巣関門 / Exome解析 … More / 性ホルモン / TP2 / プロタミン / ヒストン / 精子形成 / 遺伝子発現 / 脳 / RT-PCR / リポ多糖類 / 脈絡叢 / カリクレイン・キニン系 … More
Except Principal Investigator
ブラジキニン / アンジオテンシン受容体 / アンジオテンシン / 肝細胞増殖因子 / レニンーアンジオテンシン系 / アンジオテンシン受容体遮断薬 / アンジオテンシンII / eNOS / hypertension / angiotensin receptor / angiotensin / bradykinin / 高血圧 / ブラジキニン受容体 / キニン / キニノーゲン / タウ蛋白質 / 学習記憶機能 / タウ蛋白 / タウオパチー / Bradykinin B2 Receptor / Angiotensin AT1 Receptor / Angiotensin-Converting Enzyme Inhibitor / Angiotensin Receptor Blocker / Bradykinin / Angiotensin II / Liver Regeneration / Liver / AT1受容体 / アンジオテンシン受容体拮抗薬 / アンジオテンシン変換酵素阻害薬 / 肝再生 / 肝臓 / 一酸化窒素合成酵素 / NO合成酵素 / vessel / cardiac hypertrophy / B2-receptor / heart / カリクレイン / アンデオテンシン / 心不全 / 血管 / 心臓 / Kallikrein-Kinin System / Kinin / kininogen / ノックアウトマウス / カリクレイン・キニン系 / カリクレイン・キニン / 長期増強現象 / アルツハイマー病 Less
  • Research Projects

    (9 results)
  • Research Products

    (35 results)
  • Co-Researchers

    (8 People)
  •  β-CGの精子形成における役割の解明と雄性不妊治療モデルの構築Principal Investigator

    • Principal Investigator
      鷹野 正興
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kobe Gakuin University
  •  Elucidation of the role of Rimklb in spermatogenesis.Principal Investigator

    • Principal Investigator
      Masaoki Takano
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56040:Obstetrics and gynecology-related
    • Research Institution
      Kobe Gakuin University
  •  Study on the therapeutic effects of hepatocyte growth factor on tauopathies using transgenic mice overexpressing mutated human tau.

    • Principal Investigator
      Keiichi KADOYAMA
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Himeji Dokkyo University
  •  Analysis for the therapeutic effect of hepatocyte factor on learning and memory dysfunction in the mouse model of Alzheimer's Disease.

    • Principal Investigator
      KADOYAMA Keiichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neuroscience in general
    • Research Institution
      Himeji Dokkyo University
  •  The study of antihypertensive mechanism of angiotensin receptor blocker

    • Principal Investigator
      YAYAMA Katsutoshi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Gakuin University
  •  Enhancement of the Liver Regeneration by Angiotensin II Type 1 Receptor Blocker : Role of Angiotensin II and Bradykinin

    • Principal Investigator
      OKAMOTO Hiroshi
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kobe Gakuin University
  •  Study on the role of the kallikrein-kinin system in the cardiovascular diseases

    • Principal Investigator
      OKAMOTO Hiroshi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Gakuin University
  •  Structure Analysis of Mouse Gene Encoding Kininogens, and Construction of a Vector for Targeted Disruption of Kininogen Gene.

    • Principal Investigator
      OKAMOTO Hiroshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Gakuin University
  •  脳のカリクレイン・キニン系遺伝子発現とリポ多糖類による誘導機構に関する研究Principal Investigator

    • Principal Investigator
      鷹野 正興
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kobe Gakuin University

All 2022 2021 2020 2016 2015 2013 2012 2011 2010 2009 2005 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] Proteomic analysis of the heart in normal aging mice2022

    • Author(s)
      Maekura Koji、Yamano Ryo、Matsuura Kenji、Kadoyama Keiichi、Matsuyama Shogo、Hamada Michiko、Takano Masaoki
    • Journal Title

      J. Med. Invest.

      Volume: 69 Issue: 3.4 Pages: 217-223

    • DOI

      10.2152/jmi.69.217

    • ISSN
      1343-1420, 1349-6867
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Journal Article] Rimklb mutation causes male infertility in mice2021

    • Author(s)
      Maekura K, Tsukamoto S, Hamada-Kanazawa M, Takano M.
    • Journal Title

      Scientific Reports

      Volume: 11(1) Issue: 1 Pages: 4604-4604

    • DOI

      10.1038/s41598-021-84105-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K09633, KAKENHI-PROJECT-20K18153
  • [Journal Article] The influence of chronic nicotine treatment on proteins expressed in the mouse hippocampus and cortex.2016

    • Author(s)
      Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, Shogo Matsuyama.
    • Journal Title

      European Journal of Pharmacology

      Volume: 780 Pages: 16-25

    • DOI

      10.1016/j.ejphar.2016.03.025

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500389, KAKENHI-PROJECT-25860196
  • [Journal Article] Lipid A-activated inducible nitric oxide synthase expression via nuclear factor-κB in mouse choroid plexus cells.2015

    • Author(s)
      Masaoki Takano, Mami Ohkusa, Mieko Otani, Kyong-Son Min, Keiichi Kadoyama, Katori Minami, Keiji Sano, Shogo Matsuyama.
    • Journal Title

      Immunology Letters

      Volume: 167 Issue: 2 Pages: 57-62

    • DOI

      10.1016/j.imlet.2015.07.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Journal Article] Changes in the expression of collapsin response mediator protein-2 during synaptic plasticity in the mouse hippocampus.2015

    • Author(s)
      Keiichi Kadoyama, Kenji Matsuura, Tooru Nakamura-Hirota, Masaoki Takano, Mieko Otani, Shogo Matsuyama.
    • Journal Title

      Journal of Neuroscience Research

      Volume: 93 Issue: 11 Pages: 1684-1692

    • DOI

      10.1002/jnr.23626

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500389, KAKENHI-PROJECT-25860196
  • [Journal Article] The influence of chronic ibuprofen treatment on proteins expressed in the mouse hippocampus.2015

    • Author(s)
      Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, Shogo Matsuyama
    • Journal Title

      European Journal of Pharmacology

      Volume: 752 Pages: 61-68

    • DOI

      10.1016/j.ejphar.2015.01.047

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24500389, KAKENHI-PROJECT-25860196
  • [Journal Article] Proteomic analysis of time-dependent changes in proteins expressed in mouse hippocampus during synaptic plasticity induced by GABAA receptor blockade.2013

    • Author(s)
      Kenji Matsuura, Tooru Nakamura-Hirota, Masaoki Takano, Mieko Otani, Keiichi Kadoyama, Shogo Matsuyama
    • Journal Title

      Neuroscience Letters

      Volume: 555 Pages: 18-23

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Journal Article] The expression changes of EphA3 receptor during synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors.2012

    • Author(s)
      Tooru Nakamura-Hirota, Keiichi Kadoyama, Masaoki Takano, Mieko Otani, Shogo Matsuyama
    • Journal Title

      NeuroReport

      Volume: 23 (13) Issue: 13 Pages: 746-749

    • DOI

      10.1097/wnr.0b013e3283565144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Journal Article] Phosphoproteome profiling using a fluorescent phosphosensor dye in two-dimensional polyacrylamide gel electrophoresis.2011

    • Author(s)
      Otani M, Taniguchi T, Sakai A, Seta J, Kadoyama K, Nakamura-Hirota T, Matsuyama S, Sano K, Takano M
    • Journal Title

      Appl.Biochem.Biotechnol. 164

      Pages: 804-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors.2011

    • Author(s)
      Nishimoto T, Kadoyama K, Taniguchi T, Takano M, Otani M, Nakamura-Hirota T, Lu Y, Matsumoto A, Matsuyama S
    • Journal Title

      Neurosci.Lett. 489

      Pages: 25-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Synaptotagmin1 synthesis induced by synaptic plasticity in mouse hippocampus through activation of nicotinic acetylcholine receptors.2011

    • Author(s)
      Takaaki Nishimoto, Keiichi Kadoyama, Taizo Taniguchi, Masaoki Takano, Mieko Otani, Tooru Nakamura-Hirota, Yabin Lu, Akira Matsumoto, Shogo Matsuyama, (equally contribution)
    • Journal Title

      Neuroscience Letters

      Volume: 489(1) Pages: 25-29

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice.2009

    • Author(s)
      Masaoki Takano, Mieko Otani, Akiko Sakai, Keiichi Kadoyama, Shogo Matsuyama, Akira Matsumoto, Mariko Takenokuchi, MihoSumida, Taizo Taniguchi
    • Journal Title

      NeuroReport 20

      Pages: 1648-1653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Use of a phosphosensor dye in proteomic analysis of human mutant tau transgenic mice.2009

    • Author(s)
      Takano M, Otani M, Sakai A, Kadoyama K, Matsuyama S, Matsumoto A, Takenokuchi M, Sumida M, Taniguchi T
    • Journal Title

      NeuroReport 20

      Pages: 1648-1653

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Journal Article] Angiotensin type 2 receptor-mediated Phosphorylation of eNOS in the Aortas of mice with 2-kidney, 1-clip hypertension.2005

    • Author(s)
      Hiromi Hiyoshi, Katsutoshi Yayama, Masaoki Takano, Hiroshi Okamoto
    • Journal Title

      Hypertension 45

      Pages: 967-973

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590074
  • [Journal Article] Stimulation of cyclic GMP production via AT_2 and B2 receptors in the pressure-overloaded aorta after banding.2004

    • Author(s)
      Hiromi Hiyoshi, Katsutoshi Yayama, MasaokiHypertension Takano, Hiroshi Okamoto
    • Journal Title

      Hypertension 43

      Pages: 1258-1263

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16590074
  • [Patent] 不妊モデル動物2020

    • Inventor(s)
      鷹野正興
    • Industrial Property Rights Holder
      神戸学院大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-072388
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Patent] 特許2020

    • Inventor(s)
      鷹野正興
    • Industrial Property Rights Holder
      学校法人神戸学院
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-072388
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Presentation] Rimklb遺伝子の変異はマウスにおいて雄性不妊を引き起こす2022

    • Author(s)
      鷹野 正興 、前倉 孝治、塚本 智史、濱田美知子、土井賢太郎
    • Organizer
      日本薬学会第142年会(名古屋)
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Presentation] Rimklb遺伝子の変異はマウスにおいて雄性不妊を引き起こす2022

    • Author(s)
      鷹野 正興、前倉 孝治、塚本 智史、濱田 美知子、土井 賢太郎
    • Organizer
      日本薬学会第142回年会
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Presentation] Rimklb mutation causes male infertility in mice.2021

    • Author(s)
      鷹野 正興 、前倉 孝治、塚本 智史、濱田美知子、土井賢太郎
    • Organizer
      日本分子生物学会第44回年会(横浜)
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Presentation] 雄性不妊に関わる新規因子の発見2020

    • Author(s)
      鷹野正興
    • Organizer
      BIOJAPAN 2020
    • Data Source
      KAKENHI-PROJECT-20K09633
  • [Presentation] イブプロフェンを長期投与したマウス海馬のプロテオーム解析2016

    • Author(s)
      松浦健二、角山圭一、鷹野正興、尾谷美枝子、松山正剛
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-09
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Presentation] The influence of chronic nicotine treatment on proteins expressed in the mouse hippocampus and cortex.2015

    • Author(s)
      Kenji Matsuura, Mieko Otani, Masaoki Takano, Keiichi Kadoyama, Shogo Matsuyama.
    • Organizer
      25th Meeting of the International Society for Neurochemistry
    • Place of Presentation
      Cairns, Australia
    • Year and Date
      2015-08-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Presentation] ニコチン受容体刺激によるLTP 様作用発現下でのマウス海馬におけるCRMP2 経時的発現変化2013

    • Author(s)
      松浦 健二、角山 圭一、廣田 徹、鷹野 正興、尾谷 三枝子、松山 正剛
    • Organizer
      第86回 日本薬理学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Presentation] GABA_A受容体阻害剤bicuculline投与によるマウス海馬のプロテオミクス解析2010

    • Author(s)
      廣田徹、鷹野正興、尾谷三枝子、角山圭一、松山正剛
    • Organizer
      BMB2010
    • Place of Presentation
      神戸国際会議場等(兵庫県)
    • Year and Date
      2010-12-07
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] GABAA受容体阻害剤bicuculline投与によるマウス海馬のプロテオミクス解析BMB20102010

    • Author(s)
      廣田徹、鷹野正興、尾谷三枝子、角山圭一、松山正剛
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] SJLBマウスとAPP変異マトランスジェニックマウスにおけるリン酸化プロテオーム解析2009

    • Author(s)
      鷹野正興, 尾谷三枝子, 富山貴美, 森啓, 谷口泰造, 角山圭一, 松山正剛
    • Organizer
      第82回日本薬理学会・年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] SJLBマウスとAPP変異マトランスジェニックマウスにおける リン酸化プロテオーム解析2009

    • Author(s)
      鷹野正興、尾谷三枝子、富山貴美、森啓、谷口泰造、角山圭一、松山正剛
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Phosphoproteome profiling of human tau with N279K mutation transgenic mice.2009

    • Author(s)
      Takano M, Otani M, Sano K, Kadoyama K, Matsuyama S, Taniguchi T
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      Busan, Korea
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] Phosphoproteome profiling of human tau with N279K mutation transgenic mice.2009

    • Author(s)
      Masaoki Takano, Mieko Otani, Keiji Sano, Keiichi Kadoyama, Shogo Matsuyama, Taizo Taniguchi
    • Organizer
      The 22nd Biennial Meeting of the ISN/APSN Joint Meeting
    • Place of Presentation
      BEXCO, Busan, KOREA
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] ニコチン投与によるマウス海馬における長期増強様作用発現下でのprefoldin subunit 5の経時的発現変化

    • Author(s)
      松浦健二、角山圭一、鷹野正興、尾谷三枝子、松山正剛
    • Organizer
      第88回 日本薬理学会年会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-03-18 – 2015-03-20
    • Data Source
      KAKENHI-PROJECT-24500389
  • [Presentation] 脈絡叢上皮細胞ECPC-4細胞における炎症性タンパク発現とLPSによるその誘導

    • Author(s)
      鷹野正興、大草真美、松山正剛、廣田徹、角山圭一、尾谷三枝子、佐野圭二
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      グランシップ等(静岡県)(開催中止)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] ニコチンによって誘導されるマウス海馬におけるin vivo LTP様作用下でのEphA3受容体発現の経時的変化

    • Author(s)
      廣田徹、鷹野正興、尾谷三枝子、角山圭一、松山正剛
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜(開催中止)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] 脈絡叢上皮細胞ECPC-4細胞における炎症性タンパク発現とLPSによるその誘導

    • Author(s)
      鷹野正興、大草真美、松山正剛、廣田徹、角山圭一、尾谷三枝子、佐野圭二
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡(開催中止)
    • Data Source
      KAKENHI-PROJECT-20500295
  • [Presentation] ニコチンによって誘導されるマウス海馬におけるin vivo LTP様作用下でのEphA3受容体発現の経時的変化

    • Author(s)
      廣田徹、鷹野正興、尾谷三枝子、角山圭一、松山正剛
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)(開催中止)
    • Data Source
      KAKENHI-PROJECT-20500295
  • 1.  OKAMOTO Hiroshi (00028870)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 2.  YAYAMA Katsutoshi (30248108)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 2 results
  • 3.  KADOYAMA Keiichi (70454767)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 25 results
  • 4.  MATSUYAMA Shogo (80243319)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 25 results
  • 5.  TANIGUCHI Taizo (70346253)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 6.  FUNAKOSHI Hiroshi (40273685)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  OTANI Mieko (40068284)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 25 results
  • 8.  MATSUMOTO Akira (80181759)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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