DOI Yoshiaki 土肥良秋

Researcher Number	30258602
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2011: 産業医科大学, 医学部, 教授 2007 – 2009: University of Occupational and Environmental Health, Japan, 医学部, 教授 2002 – 2005: University of Occupational and Environmental Health, School of Medicine, Department of Anatomy, Professor, 医学部, 教授 1996 – 2001: Univ. Occup. Environ. Health, Sch. Med., Dept. Anat., Associate Professor, 医学部, 助教授 1994 – 1995: Univ.Occup.Environ.Health, Sch.Med., Dept.Anat., Assistant Professor, 医学部, 講師 1993: 産業医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator General anatomy (including Histology/Embryology) / General anatomy (including Histology/Embryology) Except Principal Investigator General anatomy (including Histology/Embryology) / Environmental physiology (including Physical medicine and Nutritional physiology)
Keywords	Principal Investigator 免疫細胞化学 / 血管内皮細胞 / basic FGF / VEGF / endothelial progenitor cell / endothelial cell / wound healing / vasculogenesis / 血管内皮前駆細胞 / 創傷治癒 … More / 熱傷モデル / 細胞培養 / PKR / cell culture / fibroblast / BrdU / 線維芽細胞 / 血管新生 / VEGF receptor / immunocytochemistry / burn injury / Weibel-Palade body / 血管形成 / VEGF受容体 / Weibel-Palade小体 / 血管発生 / Thioacetamide / Hepatic stellate cell / Liver fibrosis / Endothelin receptor / Preproendothelin-1 mRNA / Endothelin-1 / In situ hybridization / Immunocytochemistry / エンドセリン受容体 / 肝硬変症 / ラット / チオアセトアミド / in situ hybridization / 伊東細胞 / 実験的肝硬変モデル / 肝線維化 / エンドセリン-1 / 免疫抑制剤 / 転写因子 / 分化調節 / 小腸上皮 / 走査型電子顕微鏡 / 分化誘導 / ウェスタンブロッティング / real time RT-PCR / ラット壁細胞 / 合成二本鎖RNA / ヒドロコルチゾン / 免疫組織化学 / IEC6細胞 / PKR阻害薬 / ラット小腸上皮細胞 / STAT-1 / ハイドロコルチゾン / 二本鎖RNA依存性プロテインキナーゼ(PKR) / アポトーシス / 小腸上皮細胞 / 細胞分化 / 80 / compound48 / 線維芽細胞増殖因子 / Weibel-palade小体 / ヒト臍帯静脈 … More Except Principal Investigator Weibel-Palade body / CGRP / エンドセリン-1 / in situ hybridization / immunocytochemistry / ワイベル・パラ-デ小体 / エンドセリン / 血管内皮細胞 / hypoxia / endothelin-1 / 免疫細胞化学 / endothelial cell / カルシトニン遺伝子関連ペプチド / エンドセリン受容体 / 血管作動性ペプチド / ビック・エンドセリン / 脳硬静脈洞 / 頸動脈小体動脈 / 免疫電顕 / 脳硬膜静脈洞 / ワイベル・パラ-デ顆粒 / gene / circulation / brain / fluorescence / green fluorescent protein (GFP) / nitric oxide synthase / nitric oxide / nucleus tractus solitarii / 孤束核 / 遺伝子 / 循環 / 脳 / 蛍光 / green fluorescent protein(GFP) / 一酸化窒素合成酵素 / 一酸化窒素 / 弧束核 / endothelin-converting enzyme / in-situ hybridization / Weibel-Palade bodies / cadmium / mRNA / 細胞培養 / ヒト臍帯静脈内皮細胞 / 急性カドミウム中毒 / RT-PCR / エンドセリン変換酵素 / Weibel-Palade小体 / カドミウム / 低酸素 / endothelin receptor / calcitonin gene-related peptide / ワイベル・パラーテ小体 / ワイベル・パラーデ小体 / 低酸素血症 / カルシトニン遺伝子関係ペプチド / carotid body artery / enous sinus of dura mater vascular / endothelin receptors / endothlin-1 / Transverse sinus of dura mater / Endothelin / Vascular endothelial cell / 二重標識免疫電顕 / 臍静脈 / プロエンドセリン / 血管作動性物質 Less

PKRによる小腸上皮機能構築機序の分子形態学的解析Principal Investigator
- Principal Investigator
  
  土肥良秋
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health, Japan
The expression and function of double-stranded RNA-dependent protein kinase (PKR) in rat intestinal epithelial cellsPrincipal Investigator
- Principal Investigator
  
  DOI Yoshiaki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health, Japan
Identification of endothelial progenitor cells derived from cultured fibroblasts of the rat dermisPrincipal Investigator
- Principal Investigator
  
  DOI Yoshiaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
Electron microscopy and immunocytochemistry on endothelial progenitor cells during healing process of burn injury in adult ratsPrincipal Investigator
- Principal Investigator
  
  DOI Yoshiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
Observation of the motion of a single molecule of neuronal nitric oxide synthase in the nucleus tractus solitarius
- Principal Investigator
  
  MAEDA Masanobu
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Wakayama Medical Universtiy
The roles of Weibel-Palade bodies in processing and release of endothelin-1
- Principal Investigator
  
  FUJIMOTO Sunao
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
Roles of endothelin-1 in normal and fibrotic rat liversPrincipal Investigator
- Principal Investigator
  
  DOI Yoshiaki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
Immunocytochemistry and in situ hybridization of some vasoactive peptides and their receptors
- Principal Investigator
  
  FUJIMOTO Sunao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
血管内皮細胞における線維芽細胞増殖因子の貯蔵および放出機構の解明Principal Investigator
- Principal Investigator
  
  土肥良秋
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health, Japan
Immunolocalizations of ET-1, ET receptors and CGRP in endothelial cells
- Principal Investigator
  
  FUJIMOTO Sunao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health
Storage and Release of Endothelin in Vascular Endothelial Cells
- Principal Investigator
  
  FUJIMOTO Sunao
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  University of Occupational and Environmental Health

All 2010 2009 2008 2007 2005 2004 2003

All Journal Article Book

[Book] 第7章内分泌系、第11章感覚器系、ビジュアル解剖生理学2007
- Author(s)
  土肥良秋, 他
- Publisher
  ヌーヴェルヒロカワ
- Data Source
  KAKENHI-PROJECT-19590201
[Book] Proceedings of the 8th Asia-Pacific Conference on Electron Microscopy2004
- Author(s)
  Yoshiaki Doi 他(第1著者)
- Data Source
  KAKENHI-PROJECT-15590179
[Book] Proceedings of the 8th Asia-Pacific Conference on Electron Microscopy2004
- Author(s)
  Yoshiaki Doi 他
- Publisher
  The enhancement of endothelin-1 synthesis and processing in the acute hypoxic rat aorta
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] Functional expression of double-stranded RNA-dependent proein kinase in rat intestinal epithelial cells2010
- Author(s)
  Sato, N. 、Morimoto, H. 、Baba, R. 、Nakamata, J. 、Doi, Y. 、Yamaguchi, K.
- Journal Title
  
  J. Cell. Biochem. Vol.110
  
  Pages: 104-111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] Expressions of the multidrug resistance-related proteins in the rat olfactory epithelium: A possible role in the phaseIIIxenobiotic metabolizing function2010
- Author(s)
  Kudo, H. 、Doi, Y. 、Fujimoto, S.
- Journal Title
  
  Neurosci. Lett. Vol.468、No.2
  
  Pages: 98-101
- NAID
  120001702386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] Molecular characterization and histochemical demonstration of salmon olfactory marker protein in the olfactory epithelium of lacustrine sockeye salmon (Oncorhynchus nerka)2009
- Author(s)
  Kudo, H. 、Doi, Y. 、Ueda, H. 、Kaeriyama, M.
- Journal Title
  
  Comp. Biochem. Physiol. A Mol. Inteqr. Physiol. Vol.154、No.1
  
  Pages: 142-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] Antioxidant enzyme immunoreactivity in rat von Ebner gland after nickel treatment2008
- Author(s)
  Shiraishi, M. 、Doi, Y. 、Kayashima, K. 、Fujimoto, S.
- Journal Title
  
  Med. Mol. Morphol. Vol.41、No.1
  
  Pages: 44-52
- NAID
  10024380732
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] 乳飲期回腸吸収上皮におけるエンドサイトーシスの膜系と細胞骨格の関連2008
- Author(s)
  馬場良子、佐藤永洋、土肥良秋、藤田守
- Journal Title
  
  医学生物学電子顕微鏡技術学会誌 Vol.22、No.2
  
  Pages: 62-62
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] Immunoreactivities for glutathione S-transferases and glutathione peroxidase in the lateral wall of pigmented and albino guinea pig cochlea2008
- Author(s)
  Fujimura, T. 、Suzuki, H. 、Udaka, T. 、Shiomori, T. 、Mori, T. 、Inaba, T. 、Hiraki, N. 、Kayashima, K. 、Doi, Y.
- Journal Title
  
  Med. Mol. Morphol. Vol.41、No.3
  
  Pages: 139-144
- NAID
  10024381153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] 怒ると怖い血管内皮細胞2007
- Author(s)
  土肥良秋
- Journal Title
  
  ミクロスコピア Vol.24、No.2
  
  Pages: 98-104
- Data Source
  KAKENHI-PROJECT-19590201
[Journal Article] Increased immunoreactivities against endothelin-converting enzyme-1 and monocyte chemotactic protein-1 in hepatic stellate cells of rat fibrous liver induced by thioacetamide2005
- Author(s)
  Nagata, T., Kudo, H., Nishino, T., Doi, Y., Itoh, H., Fujimoto, S.
- Journal Title
  
  Medical Molecular Morphology 38(3)
  
  Pages: 161-172
- NAID
  10018373916
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] The enhancement of preproendothelin-1 synthesis and the acceleration of endothelin-1 processing in the acute hypoxic rat aorta2004
- Author(s)
  Yoshiaki Doi 他(第1著者)
- Journal Title
  
  Journal of Cardiovascular Pharmacology 44・Suppl
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] The enhancement of endothelin-1 synthesis and processing in the acute hypoxic rat aorta2004
- Author(s)
  Doi, Y., Kudo, H., Nishino, T., Kiyonaga, H., Nagata, T., Hamasaki, K., Fujimoto, S.
- Journal Title
  
  Proceedings of the 8th Asia-Pacific Conference on Electron Microscopy (8APEM),(Tanaka, N., Takano, Y., Mori, H., Seguchi, H., Iseki, S., Shimada, H., Simamura, E.(eds.))(8APEM Publication Committee, Uchinada(Ishikawa))
  
  Pages: 933-934
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] The enhancement of preproendothelin-1 synthesis and the acceleration of endothelin-1 processing in the acute hypoxic rat aorta.2004
- Author(s)
  Doi, Y., Kudo, H., Nishino, T., Nagata, T., Fujimoto, S.
- Journal Title
  
  Journal of Cardiovascular Pharmacology 44(Suppl.1)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] The enhancement of preproendothelin-1 synthesis and the acceleration of endothelin-1 processing in the acute hypoxic rat aorta2004
- Author(s)
  Yoshiaki Doi 他
- Journal Title
  
  Journal of Cardiovascular Pharmacology 44・Suppl
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] 血管発生と血管新生 -新生血管形成に関する研究の沿革-2003
- Author(s)
  土肥良秋他
- Journal Title
  
  産業医科大学雑誌 25・4
  
  Pages: 409-417
- NAID
  110001259589
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590179
[Journal Article] Vasculogenesis and angiogenesis2003
- Author(s)
  Doi, Y., Kudo, H., Nishino, T., Fujimoto, S.
- Journal Title
  
  Journal of UOEH 25(4)
  
  Pages: 409-417
- NAID
  110001259589
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590179

1. FUJIMOTO Sunao (80080547)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
2. KUDO Hideaki (40289575)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. MORIMOTO Hiroyuki (30335806)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MAEDA Masanobu (80181593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. OWADA-MAKABE Kyoko (10203952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TSUBOTA Yuji (50197761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YUKAWA Kazunori (20301434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 馬場良子 (90271436)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

DOI Yoshiaki 土肥 良秋

Research Projects

Research Products

Co-Researchers

PKRによる小腸上皮機能構築機序の分子形態学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The expression and function of double-stranded RNA-dependent protein kinase (PKR) in rat intestinal epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of endothelial progenitor cells derived from cultured fibroblasts of the rat dermisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Electron microscopy and immunocytochemistry on endothelial progenitor cells during healing process of burn injury in adult ratsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Observation of the motion of a single molecule of neuronal nitric oxide synthase in the nucleus tractus solitarius

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The roles of Weibel-Palade bodies in processing and release of endothelin-1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of endothelin-1 in normal and fibrotic rat liversPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunocytochemistry and in situ hybridization of some vasoactive peptides and their receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管内皮細胞における線維芽細胞増殖因子の貯蔵および放出機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Immunolocalizations of ET-1, ET receptors and CGRP in endothelial cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Storage and Release of Endothelin in Vascular Endothelial Cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 第7章内分泌系、第11章感覚器系、ビジュアル解剖生理学2007

Author(s)

Publisher

Data Source

[Book] Proceedings of the 8th Asia-Pacific Conference on Electron Microscopy2004

Author(s)

Data Source

[Book] Proceedings of the 8th Asia-Pacific Conference on Electron Microscopy2004

Author(s)

Publisher

DOI Yoshiaki 土肥良秋