NISHI Kazuhiko 西一彦

… Alternative Names

西一彦ニシカズヒコ

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Researcher Number	30264287
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2016: 熊本大学, 医学部附属病院, 准教授 2010: 熊本大学, 医学部附属病院, 准教授 2001: Kumamoto University, School of Medicine, Assistant professor, 医学部附属病院, 講師 2000 – 2001: 熊本大学, 医学部・附属病院, 講師
Review Section/Research Field	Principal Investigator Urology Except Principal Investigator Medical pharmacy
Keywords	Principal Investigator HIFU / Effect / Safety / Renat tumor / 生存率 / 長期効果 / 治療効果 / 安全性 / 腎癌 Except Principal Investigator インドキシル硫酸 … More / 代謝スクリーニング系 / 急性腎障害 / 硫酸転移酵素 / 腎臓病 / 尿毒症物質 / 代謝スクリーニング / 薬物動態 / 透析による薬物除去 / 透析除去率予測式 / AN69膜 / アミノグリコシド系抗菌 / 透析膜への薬物吸着 / 透析による薬物除 / 血液透析 / 超小型透析器 / 薬物吸着 / タンパク結合率 / 分布容積 / 透析ラットモデル / 吸着 / 透析膜 / 薬物の透析性 Less

Development of renoprotective and uremia therapeutic drug seeds based on inhibition of hepatic production of sulfate-conjugated uremic solutes
- Principal Investigator
  
  Saito Hideyuki
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Construction of clinical usable prediction formula for removal rate by hemodialysis
- Principal Investigator
  
  HIRATA SUMIO
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kumamoto University
Application study of High Intensity Focused Ultrasound for renal tumorPrincipal Investigator
- Principal Investigator
  
  NISHI Kazuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Kumamoto University

All 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Indoxyl Sulfate as a Mediator Involved in Dysregulation of Pulmonary Aquaporin-5 in Acute Lung Injury Caused by Acute Kidney Injury.2016
- Author(s)
  Yabuuchi N, Sagata M, Saigo C, Yoneda G, Yamamoto Y, Nomura Y, Nishi K, Fujino R, Jono H, Saito H.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Issue: 1 Pages: 11-11
- DOI
  10.3390/ijms18010011
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040
[Journal Article] Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.2014
- Author(s)
  Saito H, Yoshimura M, Saigo C, Komori M, Nomura Y, Yamamoto Y, Sagata M, Wakida A, Chuman E, Nishi K, Jono H.
- Journal Title
  
  Toxicol. Sci.
  
  Volume: 141 Issue: 1 Pages: 206-217
- DOI
  10.1093/toxsci/kfu119
- NAID
  120005663611
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040, KAKENHI-PROJECT-25670080
[Journal Article] Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters.2014
- Author(s)
  Saigo C, Nomura Y, Yamamoto Y, Sagata M, Matsunaga R, Jono H, Nishi K, Saito H.
- Journal Title
  
  Drug Des. Devel. Ther.
  
  Volume: 8 Pages: 1073-1082
- DOI
  10.2147/dddt.s67456
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293040, KAKENHI-PROJECT-25670080
[Journal Article] Japanese Society for Dialysis Therapy guidelines for management of cardiovascular diseases in patients on chronic hemodialysis.2012
- Author(s)
  Hirakata H, Nitta K, Inaba M, Shoji T, Fujii H, Kobayashi S, Tabei K, Joki N, Hase H, Nishimura M, Ozaki S, Ikari Y, Kumada Y, Tsuruya K, Fujimoto S, Inoue T, Yokoi H, Hirata S, et al
- Journal Title
  
  Ther Apher Dial
  
  Volume: 16 Pages: 387-435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590136
[Journal Article] （社）日本透析医学会「血液透析患者における心血管合併症の評価と治療に関するガイドライン」.2012
- Author(s)
  平方秀樹, 新田孝作, 友　雅司, 秋葉　隆, 伊苅裕二, 井関邦敏, 稲葉雅章, 井上　亨, 熊田佳孝, 小林修三, 常喜信彦, 庄司哲雄, 椿原美治, 鶴屋和彦, 田部井薫, 西村眞人, 長谷弘記, 平田純生, 他
- Journal Title
  
  透析会誌
  
  Volume: 44 Pages: 337-425
- Data Source
  KAKENHI-PROJECT-22590136
[Journal Article] Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis2011
- Author(s)
  Tanoue K, Nishi K, Kadowaki D, Hirata S
- Journal Title
  
  Ther Apher Dial
  
  Volume: 15 Issue: 3 Pages: 327-333
- DOI
  10.1111/j.1744-9987.2011.00914.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590136
[Journal Article] (社)日本透析医学会「血液透析患者における心血管合併症の評価と治療に関するガイドライン」2011
- Author(s)
  平方秀樹, 新田孝作, 友雅司, 秋葉隆, 伊苅裕二, 井関邦敏, 稲葉雅章, 井上亨, 熊田佳孝, 小林修三, 常喜信彦, 庄司哲雄, 椿原美治, 鶴屋和彦, 田部井薫, 西村眞人, 長谷弘記, 平田純生, 藤井秀毅, 藤元昭一, 横井宏佳, 島本和明, 久木山清貴
- Journal Title
  
  透析会誌
  
  Volume: 44(不明) Pages: 337-425
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590136
[Journal Article] Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis.2011
- Author(s)
  Tanoue K, Nishi K, Kadowaki D, Hirata S
- Journal Title
  
  Ther Apher Dial
  
  Volume: (In print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590136
[Presentation] CKD 病態進展における腫瘍抑制遺伝子CYLD発現消失の臨床的意義2016
- Author(s)
  城野博史、三宅俊介、米田剛、末永尚輝、薮内希実、西一彦、齋藤秀之
- Organizer
  第26回日本医療薬学会年会
- Place of Presentation
  京都
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Involvement of CYLD as a regulatory factor in fibrotic response of ischemic AKI kidney and hypoxic HK-2 cells2015
- Author(s)
  Yoneda G, Suenaga N, Yabuuchi N, Nishi K, Jono H, Saito H
- Organizer
  2015 American Society of Nephrology Annual Meeting
- Place of Presentation
  Saｎ Diego, USA
- Year and Date
  2015-11-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] CKD 病態進展における慢性炎症制御因子CYLD の病態生理学的意義2015
- Author(s)
  米田剛、末永尚輝、薮内希実、西一彦、城野博史、齋藤秀之
- Organizer
  第58回日本腎臓学会学術総会
- Place of Presentation
  名古屋　名古屋国際会議場
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 硫酸転移酵素（SULT）を標的とした新規腎保護・治療薬の開発2015
- Author(s)
  西郷智香、野村祐衣、米田剛、山本悠子、城野博史、齋藤秀之
- Organizer
  医療薬学フォーラム2015／第23回クリニカルファーマシーシンポジウム
- Place of Presentation
  名古屋　名古屋国際会議場
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 虚血性急性腎障害ラットにおけるインドキシル硫酸産生阻害の腎保護効果2014
- Author(s)
  野村結衣、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 両腎摘出急性腎障害モデルラットにおいてインドキシル硫酸が肺aquaporin-5の発現減少に関与する2013
- Author(s)
  佐潟雅隆、西郷智香、山本悠子、米田剛、野村祐衣、西一彦、城野博史、齋藤秀之
- Organizer
  第34回日本臨床薬理学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 虚血再灌流急性腎障害に伴うNrf2活性化にインドキシル硫酸蓄積が関与する2013
- Author(s)
  佐潟雅隆、吉村美里、脇田紋佳、西郷智香、山本悠子、米田剛、中馬江里奈、野村祐衣、松下裕子、西一彦、城野博史、齋藤秀之
- Organizer
  第56回日本腎臓学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 硫酸抱合型尿毒症物質の肝産生阻害を基軸とする腎保護・治療薬の探索2013
- Author(s)
  齋藤秀之、佐潟雅隆、西郷智香、西一彦
- Organizer
  BIOJAPAN2013/World Business Forum
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] Involvement of Indoxyl sulfate (IS) in downregulation of pulmonary aquaporin (AQP)-5 in rats caused by bilateral nephrectomy (BNx)-induced acute kidney injury (AKI).2013
- Author(s)
  Sagata M, Saigo C, Yoneda G, Yamamoto Y, Nomura Y, Nishi K, Jono H, Saito H.
- Organizer
  アメリカ腎臓学会第４６回年会
- Place of Presentation
  アトランタ
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 虚血再灌流急性腎障害ラットにおけるインドキシル硫酸産生阻害薬物の腎保護効果2013
- Author(s)
  西郷智香、佐潟雅隆、野村祐依、松永里香、西一彦、齋藤秀之
- Organizer
  第34回日本臨床薬理学会学術総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 腎部分切除における尿中L-FABPおよび酸化ストレスマーカーの変動.2012
- Author(s)
  宮地亜由美, 西一彦, 門脇大介, 成田勇樹, 平田純生:
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590136
[Presentation] 肝硫酸転移酵素SULTを標的とするインドキシル硫酸産生阻害薬の腎保護作用と機序解明
- Author(s)
  齋藤秀之、西一彦
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-03 – 2014-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 硫酸転移酵素（SULT）阻害薬によるインドキシル硫酸（IS）蓄積抑制と急性腎障害低減効果の検証
- Author(s)
  野村祐依、西郷智香、佐潟雅隆、松永里香、城野博史、西一彦、齋藤秀之
- Organizer
  第57回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-07-03 – 2014-07-05
- Data Source
  KAKENHI-PROJECT-25293040
[Presentation] 虚血再灌流急性腎障害ラットにおけるメクロフェナム酸の腎保護効果
- Author(s)
  西郷智香、野村結衣、米田剛、山本悠子、城野博史、齋藤秀之
- Organizer
  第8回次世代を担う若手医療薬科学シンポジウム
- Place of Presentation
  熊本
- Year and Date
  2014-11-15 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25293040

1. HIRATA SUMIO (10432999)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. KADOWAKI Daisuke (70433000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. Saito Hideyuki (40225727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 竹澤真吾 (30171630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 城野博史 (40515483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
6. SAIGO Chika

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. SAGATA Masataka

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. 斎藤秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 16 results

NISHI Kazuhiko 西 一彦

西 一彦 ニシ カズヒコ

Research Projects

Research Products

Co-Researchers

Development of renoprotective and uremia therapeutic drug seeds based on inhibition of hepatic production of sulfate-conjugated uremic solutes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of clinical usable prediction formula for removal rate by hemodialysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application study of High Intensity Focused Ultrasound for renal tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Indoxyl Sulfate as a Mediator Involved in Dysregulation of Pulmonary Aquaporin-5 in Acute Lung Injury Caused by Acute Kidney Injury.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatic sulfotransferase as a nephropreventing target by suppression of the uremic toxin indoxyl sulfate accumulation in ischemic acute kidney injury.2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Meclofenamate elicits a nephropreventing effect in a rat model of ischemic acute kidney injury by suppressing indoxyl sulfate production and restoring renal organic anion transporters.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Japanese Society for Dialysis Therapy guidelines for management of cardiovascular diseases in patients on chronic hemodialysis.2012

Author(s)

Journal Title

Data Source

[Journal Article] （社）日本透析医学会「血液透析患者における心血管合併症の評価と治療に関するガイドライン」.2012

Author(s)

Journal Title

Data Source

[Journal Article] Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (社)日本透析医学会「血液透析患者における心血管合併症の評価と治療に関するガイドライン」2011

Author(s)

Journal Title

Data Source

[Journal Article] Removal of doripenem during hemodialysis and the optimum dosing regimen for patients undergoing hemodialysis.2011

Author(s)

Journal Title

Data Source

[Presentation] CKD 病態進展における腫瘍抑制遺伝子CYLD発現消失の臨床的意義2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Involvement of CYLD as a regulatory factor in fibrotic response of ischemic AKI kidney and hypoxic HK-2 cells2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] CKD 病態進展における慢性炎症制御因子CYLD の病態生理学的意義2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 硫酸転移酵素（SULT）を標的とした新規腎保護・治療薬の開発2015

Author(s)

NISHI Kazuhiko 西一彦

西一彦ニシカズヒコ