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Adachi Noritaka  足立 典隆

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ADACHI Noritaka  足立 典隆

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Researcher Number 30264675
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 教授
Affiliation (based on the past Project Information) *help 2013 – 2024: 横浜市立大学, 生命ナノシステム科学研究科(八景キャンパス), 教授
2015: 横浜市立大学, 生命ナノシステム科学研究科, 教授
2012: 横浜市立大学, 生命ナノシステム研究科, 教授
2010 – 2012: 横浜市立大学, 生命ナノシステム科学研究科, 教授
2009: Yokohama City University, 生命ナノシステム科学研究科, 准教授 … More
2007 – 2008: Yokohama City University, International Graduate School of Arts and Sciences, Associate Professor
2006: 横浜市立大学, 木原生物学研究所, 準教授
1998 – 2005: 横浜市立大学, 木原生物学研究所, 助手
2004: Yokohama City University, Kihara Institute for Biological Research, Dev. Mol. Cell Genetics, Assistant Professor, 助手 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Biological Sciences / Medium-sized Section 47:Pharmaceutical sciences and related fields / Biological pharmacy / Medium-sized Section 63:Environmental analyses and evaluation and related fields / System genome science / Applied genomics / Biological Sciences
Except Principal Investigator
Biological Sciences / Molecular biology / Risk sciences of radiation and chemicals / Hematology
Keywords
Principal Investigator
ジーンターゲティング / DNA修復 / DNA鎖切断 / エンドジョイニング / トポイソメラーゼ / Nalm-6 / 非相同組換え / ゲノム編集 / 遺伝子ノックアウト / ノックアウト … More / 遺伝子発現 / がん / ゲノム改変 / 逆遺伝学的解析 / ヒト遺伝子 / ランダムインテグレーション / DT40 / 組換え修復 / ゲノム編集細胞 / 生体環境 / DNA切断 / 組換え修復 / NHEJ / DNAポリメラーゼ / 非相同末端連結 / ゲノム修復 / ヒトゲノム / nonhomologous recombination / gene targeting / random integration / end-ioining / DNA repair / DNA strand break / 非相同組換之 / ジーンターゲティンク / FACS解析 / ランダム挿入 / クロマチン構造 / ゲノム切断修復 / NDA鎖切断 / 組換え / DNA鎖切断修復 / 逆遺伝的解析 / DNA損傷応答 / TDP1 / p53 / DNA損傷 / 化学療法 / トポイソラーゼ / 塩基除去修復 / DNA ligase / DNAトポイソメラーゼ / FEN-1 / Ku / DNAライゲース / 細胞周期 / アセチル化 / NF-Y / プロモーター / 細胞増殖 … More
Except Principal Investigator
ジーンターゲティング / ヒト細胞 / FEN1 / 塩基除去修復 / がん / KU70 / DNAリガーゼIV / BLM / 非相同的末端連結 / ブルーム症候群 / 非相同末端連結 / DNA依存性プロテインキナーゼ / DNA-PKcs / NHEJ / DNA repair / repair / genome / cancer / gene / genetics / ゲノム不安定性 / 遺伝子相互作用 / 組換え修復 / 遺伝子破壊株 / 修復 / ゲノム / 遺伝子 / 遺伝学 / Long-patch BER / Short-patch BER / knockout cell / Gene targeting / chicken DT40 cell / DNA polymerase beta / Base excision repair / BER活性 / 相同組換え / 非相同組換え / シーンターゲティング / 塩基除去修復活性 / 薬剤感受性 / 組換え能 / ニワトリDT40細胞 / TEN1 / DNAポリメラーゼβ / 転写 / 米国 / 国際情報交流 / 網羅的解析 / マクロファージ / 細胞分化 / ヒストンH3.3 / エピジェネティックメモリー / 条件致死変異株 / 有糸分裂組換え / 突然変異 / APRT遺伝子 / ノックアウト細胞 / Ku70 / 癌 Less
  • Research Projects

    (27 results)
  • Research Products

    (114 results)
  • Co-Researchers

    (13 People)
  •  条件的遺伝子発現システムの創出に基づくDNA修復欠損がん診断・治療の新規戦略Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Yokohama City University
  •  Novel therapeutic strategies for DNA repair-deficient cancerPrincipal Investigator

    • Principal Investigator
      Adachi Noritaka
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Yokohama City University
  •  Comprehensive Insights into DNA Recombinational Repair in the Human GenomePrincipal Investigator

    • Principal Investigator
      Adachi Noritaka
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 63:Environmental analyses and evaluation and related fields
    • Research Institution
      Yokohama City University
  •  Efficient suppression of random DNA integrationPrincipal Investigator

    • Principal Investigator
      Adachi Noritaka
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      Yokohama City University
  •  Development of high-efficiency gene targeting technologiesPrincipal Investigator

    • Principal Investigator
      Noritaka Adachi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      System genome science
    • Research Institution
      Yokohama City University
  •  Genes that enable high-efficiency gene disruption in human cellsPrincipal Investigator

    • Principal Investigator
      Adachi Noritaka
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  Role of DNA-PKcs in neurogenesis

    • Principal Investigator
      Kurosawa Aya
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Risk sciences of radiation and chemicals
    • Research Institution
      Yokohama City University
  •  Development and applications of high-efficiency gene targeting in human cellsPrincipal Investigator

    • Principal Investigator
      ADACHI NORITAKA
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied genomics
    • Research Institution
      Yokohama City University
  •  Analysis of human genes that enable high-efficiency gene targetingPrincipal Investigator

    • Principal Investigator
      ADACHI Noritaka
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  ゲノム切断修復におけるクロマチン構造の役割Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Epigenetic marking by histone variant H3.3 during myeloid cell differentiation

    • Principal Investigator
      TAMURA Tomohiko
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Yokohama City University
  •  GeneticanalysisofDNAstrandbreakrepairinhumancelIsPrincipal Investigator

    • Principal Investigator
      ADACHI Noritaka
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  ヒト遺伝子ノックアウトシステムの効率化と疾患遺伝子機能解析への応用Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  ヒト染色体DNA切断とその修復機構Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  ヒトDNA鎖切断修復の逆遺伝学的解析と医療への応用Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  ヒト染色体DNA切断とその修復機構Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Genetic studies on the interaction between base excision repair and recombinational repair using human gene knockout cells

    • Principal Investigator
      KOYAMA Hideki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Yokohama City University
  •  Analysis of DNA strand break repair using human knockout cellsPrincipal Investigator

    • Principal Investigator
      ADACHI Noritaka
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  ヒト遺伝子の系統的な機能解析に向けた高効率ジーンターゲティング系の開発

    • Principal Investigator
      小山 秀機
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  ヒトプレB細胞よりBLM破壊株の作製とその非相同組換え能の解析

    • Principal Investigator
      小山 秀機
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  トポイソメラーゼ阻害剤によるゲノム損傷の修復におけるDNA鎖切断修復機構の役割Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  動物細胞のDNA鎖切断修復と非相同組換えに関する逆遺伝学的解析Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  ヒトプレB細胞よりBLM破壊株の作製とそ非相同的末端連結能の解析

    • Principal Investigator
      KOYAMA Hideki
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Yokohama City University
  •  Studies of base excision repair in cell mutants deficient. in either DNA polymerase, or flap endonuclease-1 or both, generated from chicken DT40 cells.

    • Principal Investigator
      KOYAMA Hideki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Yokohama City University, Kihara Institute for Biological Research
  •  DT40細胞を用いた非相同組換え機構の遺伝的解析Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  ニワトリDT40細胞を用いた非相同組換え機構の遺伝的解析Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University
  •  DNAトポイソメラーゼIIαの生理的機能と発現制御機構Principal Investigator

    • Principal Investigator
      足立 典隆
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Yokohama City University

All 2024 2023 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2010 2009 2007 2006 2005 2004 2003 Other

All Journal Article Presentation Patent

  • [Journal Article] Characterization and regulation of cell cycle-independent noncanonical gene targeting2024

    • Author(s)
      Saito S, Adachi N.
    • Journal Title

      Nature Communications

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19382
  • [Journal Article] Arsenic affects homologous recombination and single-strand annealing but not end-joining pathways during DNA double-strand break repair.2023

    • Author(s)
      Kurosawa A, Saito S, Sakurai M, Shinozuka M, Someya Y, Adachi N.
    • Journal Title

      FEBS Journal

      Volume: 290 Issue: 22 Pages: 5313-5321

    • DOI

      10.1111/febs.16922

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K19382
  • [Journal Article] Error-prone bypass patch by a low-fidelity variant of DNA polymerase zeta in human cells2021

    • Author(s)
      Suzuki Tetsuya、Sassa Akira、Gruz Petr、Gupta Ramesh C.、Johnson Francis、Adachi Noritaka、Nohmi Takehiko
    • Journal Title

      DNA Repair

      Volume: 100 Pages: 103052-103052

    • DOI

      10.1016/j.dnarep.2021.103052

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K12339, KAKENHI-PROJECT-19H01151, KAKENHI-PROJECT-20K12181
  • [Journal Article] Complex genetic interactions between DNA polymerase β and the NHEJ ligase.2019

    • Author(s)
      Kurosawa A, Kuboshima H, Adachi N.
    • Journal Title

      FEBS J.

      Volume: 287 Issue: 2 Pages: 377-385

    • DOI

      10.1111/febs.15012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H01151, KAKENHI-PROJECT-18K19407
  • [Journal Article] Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks.2018

    • Author(s)
      Morotomi-Yano K, Saito S, Adachi N, Yano KI.
    • Journal Title

      Sci. Rep.

      Volume: 8 Issue: 1 Pages: 10344-10344

    • DOI

      10.1038/s41598-018-28690-6

    • NAID

      120006697280

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19407, KAKENHI-PROJECT-16K01363
  • [Journal Article] TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation.2017

    • Author(s)
      Maeda R., Tamashira H., Takano K., Takahashi H., Suzuki H., Saito S., Hojima W., Adachi N., U ra K ., E ndo T . and *Tam ura T.
    • Journal Title

      J. Biol. Chem.

      Volume: 292 Issue: 8 Pages: 3201-3212

    • DOI

      10.1074/jbc.m116.763318

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01345, KAKENHI-PROJECT-15H04323, KAKENHI-PROJECT-15H04348, KAKENHI-PROJECT-15J02670, KAKENHI-PROJECT-16J04091, KAKENHI-PROJECT-26440045
  • [Journal Article] Dual loss of human POLQ and LIG4 abolishes random integration.2017

    • Author(s)
      Saito S, Maeda R, Adachi N.
    • Journal Title

      Nature Commun.

      Volume: 8 Issue: 1

    • DOI

      10.1038/ncomms16112

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04323
  • [Journal Article] Mechanistic basis for increased human gene targeting by promoterless vectors: roles of homology arms and Rad54 paralogs.2017

    • Author(s)
      Saito S, Kurosawa A, Adachi N.
    • Journal Title

      FEBS J.

      Volume: 284 Issue: 17 Pages: 2748-2763

    • DOI

      10.1111/febs.14137

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04323
  • [Journal Article] Non-homologous DNA end joining and alternative pathways to double-strand break repair.2017

    • Author(s)
      Chang HHY, Pannunzio NR, Adachi N, Lieber MR.
    • Journal Title

      Nature Rev. Mol. Cell Biol.

      Volume: 18 Issue: 8 Pages: 495-506

    • DOI

      10.1038/nrm.2017.48

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04323
  • [Journal Article] Dual loss of human POLQ and LIG4 abolishes random integration2017

    • Author(s)
      Saito S, Maeda R, Adachi N.
    • Journal Title

      Nat. Commun.

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04323
  • [Journal Article] Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency.2016

    • Author(s)
      Saito S, Kurosawa A, Adachi N.
    • Journal Title

      J Hum Genet.

      Volume: 印刷中 Issue: 8 Pages: 679-685

    • DOI

      10.1038/jhg.2016.46

    • NAID

      40020923702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04323
  • [Journal Article] Advances in the Development of Gene-Targeting Vectors to Increase the Efficiency of Genetic Modification2016

    • Author(s)
      Saito S, Adachi N.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 39 Issue: 1 Pages: 25-32

    • DOI

      10.1248/bpb.b15-00701

    • NAID

      130005116505

    • ISSN
      0918-6158, 1347-5215
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04323, KAKENHI-PROJECT-26670031
  • [Journal Article] Construction and applications of exon-trapping gene-targeting vectors with a novel strategy for negative selection.2015

    • Author(s)
      Saito S, Ura K, Kodama M, Adachi N.
    • Journal Title

      BMC Res Notes.

      Volume: 8 Issue: 1 Pages: 278-278

    • DOI

      10.1186/s13104-015-1241-6

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04323, KAKENHI-PROJECT-26670031
  • [Journal Article] Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.2015

    • Author(s)
      Moscariello M, Wieloch R, Kurosawa A, Li F, Adachi N, Mladenov E, Iliakis G.
    • Journal Title

      DNA Repair

      Volume: 31 Pages: 29-40

    • DOI

      10.1016/j.dnarep.2015.04.004

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24310149
  • [Journal Article] Role for Artemis nuclease in the repair of radiation-induced DNA double strand breaks by alternative end joining.2015

    • Author(s)
      Moscariello M, Wieloch R, Kurosawa A, Li F, Adachi N, Mladenov E, Iliakis G.
    • Journal Title

      DNA Repair

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670031
  • [Journal Article] Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.2015

    • Author(s)
      Ishii T, Hayakawa H, Sekiguchi T, Adachi N, Sekiguchi M.
    • Journal Title

      Free Radic Biol Med.

      Volume: 79 Pages: 109-116

    • DOI

      10.1016/j.freeradbiomed.2014.11.018

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24570160, KAKENHI-PROJECT-26340040, KAKENHI-PROJECT-26670031
  • [Journal Article] Analysis of the role of homology arms in gene-targeting vectors in human cells.2014

    • Author(s)
      Ishii A, Kurosawa A, Saito S, Adachi N.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 9 Pages: e108236-e108236

    • DOI

      10.1371/journal.pone.0108236

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-26670031
  • [Journal Article] in vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase2014

    • Author(s)
      A. Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R.C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      DNA Repair

      Volume: 15 Pages: 21-28

    • DOI

      10.1016/j.dnarep.2013.12.008

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035, KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
  • [Journal Article] C-terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin2013

    • Author(s)
      Liu S, Liu X, Kamdar RP, Wanotayan R, Sharma MK, Adachi N, Matsumoto Y
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 439 Issue: 2 Pages: 173-178

    • DOI

      10.1016/j.bbrc.2013.08.068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390290, KAKENHI-PROJECT-24659035
  • [Journal Article] DNA Ligase IV and Artemis Act Cooperatively to Suppress Homologous Recombination in Human Cells: Implications for DNA Double-Strand Break Repair.2013

    • Author(s)
      Kurosawa A, Saito S, So S, Hashimoto M, Iwabuchi K, Watabe H, Adachi N.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 8 Pages: e72253-e72253

    • DOI

      10.1371/journal.pone.0072253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23310041, KAKENHI-PROJECT-23510067, KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24651056, KAKENHI-PROJECT-24659035
  • [Journal Article] Both CpG methylation and AID are required for the fragility of the human Bcl-2 major breakpoint region: Implications for the timing of the breaks in the t(14;18)2013

    • Author(s)
      N. Adachi, et al.
    • Journal Title

      Mol. Cell. Biol

      Volume: 33 Pages: 947-957

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24310149
  • [Journal Article] Repair of accidental DNA double-strand breaks in the human genome and its relevance to vector DNA integration2013

    • Author(s)
      Adachi N,Saito S,Kurosawa A
    • Journal Title

      Gene Technology

      Volume: 3 Issue: 01

    • DOI

      10.4172/2329-6682.1000e107

    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] Generation and use of genetically modified human cell lines : a promising approach for in vitro toxicology studies2013

    • Author(s)
      Adachi N
    • Journal Title

      J Clinic Toxicol

      Volume: 3(5) Issue: 05 Pages: 45-45

    • DOI

      10.4172/2161-0495.s1.009

    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] Interference in DNA replieation can cause mitotic chromosomal breakage unassociated with double-strand breaks2013

    • Author(s)
      Fujita Mari, Sasanuma H, Kimiyo N. Yamamoto Harada H, Kurosawa A, Adachi N, Omura M, Hiraoka M, Takeda S, Hirota K.
    • Journal Title

      PLos One

      Volume: 8 Issue: 4 Pages: 60043-60043

    • DOI

      10.1371/journal.pone.0060043

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J06811, KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-23659152, KAKENHI-PUBLICLY-24114509, KAKENHI-PROJECT-24659035, KAKENHI-PROJECT-25281021
  • [Journal Article] Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting.2013

    • Author(s)
      Adachi N. et al.
    • Journal Title

      PLoS ONE

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] Endogenous factors causative of spontaneous DNA damage that leads to random integration in human cells.2013

    • Author(s)
      N. Adachi et al.
    • Journal Title

      Gene Technology

      Volume: 2 Issue: 01 Pages: 105-105

    • DOI

      10.4172/2329-6682.1000105

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24659035
  • [Journal Article] Restoration of mismatch repair functions in human cell line Nalm-6, which has high efficiency for gene targeting2013

    • Author(s)
      T. Suzuki, A. Ukai, M. Honma, N. Adachi and T. Nohmi
    • Journal Title

      PLoS.One

      Volume: 8 Issue: 4 Pages: e61189-e61189

    • DOI

      10.1371/journal.pone.0061189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035
  • [Journal Article] Both CpG methylation and AID are required for the fragility of the human Bcl-2 major breakpoint region : Implications for the timing of the breaks in the t(l4;l8)2013

    • Author(s)
      Cui X,Lu Z,Kurosawa A,Klemm L,Bagshaw A,Tsai A,Gemmell N,Muschen M,Adachi N,Hsieh CL,Lieber MR
    • Journal Title

      Mol Cell Biol

      Volume: 33(5) Issue: 5 Pages: 947-57

    • DOI

      10.1128/mcb.01436-12

    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] Model for MLL translocations in therapy-related leukemia involving topoisomerase IIbeta mediated DNA strand breaks and gene proximity2012

    • Author(s)
      Cowell IG,Sondka Z,Smith K,Lee KC,Manville CM,Sidorczuk-Lesthuruge M,Rance HA,Padget K,]ackson GH,Adachi N,Austin CA
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 109(23) Issue: 23 Pages: 8989-94

    • DOI

      10.1073/pnas.1204406109

    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation.2012

    • Author(s)
      Kohzaki M
    • Journal Title

      Carcinogenesis

      Volume: 33 Issue: 6 Pages: 1203-1210

    • DOI

      10.1093/carcin/bgs149

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23221005, KAKENHI-PROJECT-24659035
  • [Journal Article] Nucleofection-based gene targeting in human pre-B cells2012

    • Author(s)
      Kurosawa A, Adachi N
    • Journal Title

      Gene

      Volume: 492 Pages: 305-308

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Nucleofection-based gene targeting in human pre-B cells2012

    • Author(s)
      Kurosawa, A., Adachi, N.
    • Journal Title

      Gene

      Volume: 492 Pages: 305-308

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-23131511
  • [Journal Article] The helicase domain and C-terminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation2012

    • Author(s)
      Adachi N., et al
    • Journal Title

      Carcinogenesis

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Artemis C-terminal region facilitates efficient V(D)J recombination through its interaction with both DNA Ligase IV and DNA-PKcs.2012

    • Author(s)
      N. Adachi, et al.
    • Journal Title

      J.Exp. Med.

      Volume: 209 Issue: 5 Pages: 955-963

    • DOI

      10.1084/jem.20111437

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24659035
  • [Journal Article] LEDGF/p75-independent HIV-1 replication demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs2012

    • Author(s)
      Adachi N., et al
    • Journal Title

      PLoS Pathogens

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Impaired cell adhesion, apoptosis, and signaling in WASP genedisrupted Nalm-6 pie-B cells and recovery of cell adhesion using a transducible form of WASp2012

    • Author(s)
      Sate R, Iiizumi S, Kim ES, Honda F, Lee SK, Adachi N, Koyama H, Mizutani S, Morie T.
    • Journal Title

      Int J Hematol

      Volume: 95 Pages: 299-310

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] EDGF/pisindependent HIV-l repli cation demonstrates a role for HRP-2 and remains sensitive to inhibition by LEDGINs2012

    • Author(s)
      Schrijvers R, De Rijck J, Demeu lemeester J, Adachi N, Vets S, Ronen K, Christ F, Bushman FD, Debyser Z, Gt jsbers R.
    • Journal Title

      PLoS Pathog

      Volume: 8 Pages: 1002558-1002558

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Model for MLL translocations in therapy-related leukemia involving topoisomerase IIbeta mediated DNA strand breaks and gene proximity.2012

    • Author(s)
      Adachi N. et al.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 109 Pages: 8989-8994

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659035
  • [Journal Article] Nucleofection-based gene targeting in human pie-B cells2012

    • Author(s)
      Kurosawa A, Saito S, Mort M, Adachi N.
    • Journal Title

      Gene

      Volume: 492 Pages: 305-308

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Highefficiency gene tar geting in a human pie-B cell line : towards the human gene knockout project2010

    • Author(s)
      Adachi N.
    • Journal Title

      Genome Biol

      Volume: 11 Pages: 1-1

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors2010

    • Author(s)
      Adachi, N., et al.
    • Journal Title

      PLoS ONE 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] OGFODl, a member of the 2oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling2010

    • Author(s)
      Saito K, Adachi N, Koyama H, Matsushita M.
    • Journal Title

      FEBS Left

      Volume: 584 Pages: 3340-3347

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Functions and regulation of Artemis : A goddess in the maintenance of genome integrity.2010

    • Author(s)
      Kurosawa A, Adachi N.
    • Journal Title

      J.Radiat.Res.

      Volume: 51 Pages: 503-509

    • NAID

      10026644156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] FENl functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells2010

    • Author(s)
      Asagoshi K, Tana K, Chastain PD II, Adachi N, Sonoda E, Kikuchi K, Koyama H, NagataK, Kaufman DG, Takeda S, Wilson SH, Watanabe M, Swenberg JA, Nakamura J.
    • Journal Title

      Mol Cancer Res

      Volume: 8 Pages: 204-215

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Functions and regulation of Artemis : A goddess in the maintenance of genome integrity2010

    • Author(s)
      Kurosawa A, Adachi N.
    • Journal Title

      J Radiat Res

      Volume: 51 Pages: 503-509

    • NAID

      10026644156

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors.2010

    • Author(s)
      Adachi, N., et al.
    • Journal Title

      PLoS ONE 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20018022
  • [Journal Article] Functions and regulation of Artemis : A goddess in the maintenance of genome integrity2010

    • Author(s)
      Kurosawa, A., Adachi, N.
    • Journal Title

      J.Radiat.Res. 51(印刷中)

    • NAID

      10026644156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] FEN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells2010

    • Author(s)
      Adachi, N., et al.
    • Journal Title

      Mol.Cancer Res. 8

      Pages: 204-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] FFN1 functions in long patch base excision repair under conditions of oxidative stress in vertebrate cells.2010

    • Author(s)
      Adachi, N., et al.
    • Journal Title

      Mol.Cancer Res. 8

      Pages: 204-215

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20055017
  • [Journal Article] Functions and regulation of Artemis : A goddess in the maintenance of genome integrity.2010

    • Author(s)
      Kurosawa, A., Adachi, N.
    • Journal Title

      J.Radiat.Res. 51(印刷中)

    • NAID

      10026644156

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20055017
  • [Journal Article] Chromosomal manipulation by sitespecific recombinases and fluore scent protein-based vectors2010

    • Author(s)
      Uemura M, Niwa Y, Kakazu N, Adachi N, Kinoshita K.
    • Journal Title

      PLoS ONE

      Volume: 5 Pages: 9846-9846

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Loss of Bloom syndrome protein destabilizes human gene cluster architecture.2009

    • Author(s)
      Adachi, N., et al.
    • Journal Title

      Hum.Mol.Genet. 18

      Pages: 3417-3428

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20018022
  • [Journal Article] Genetic evidence that the nonhomologous endjoining repair pathway is involved in LINE retro transposition2009

    • Author(s)
      Suzuki J, Yamaguchi K, Kajikawa M, Ichiyanagi K, Adachi N, Koyama H, Takeda S, Okada N.
    • Journal Title

      PLoS Genetics

      Volume: 5 Pages: 1000461-1000461

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Heterozygous disruption of the DNA topoisomerase I gene confers cellular resistance to camptothecin in human cells2009

    • Author(s)
      Toyoda E, Kurosawa A, Fu j i i M, Adachi N.
    • Journal Title

      Biol Pharm Bull

      Volume: 32 Pages: 724-727

    • NAID

      110007160669

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Molecular mechanism of protein assembly on DNA double strand breaks in the nonhomologous endjoining pathway2009

    • Author(s)
      Yano K, Morotomi-Yano K, Adachi N, Akiyama H.
    • Journal Title

      J Radiat Res

      Volume: 50 Pages: 97-108

    • NAID

      10025911271

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Loss of Bloom syndrome protein destabilizes human gene cluster architecture2009

    • Author(s)
      Killen MW, Stults DM, Adachi N, Hanakahi L, Pierce AJ.
    • Journal Title

      Hum Mol Genet

      Volume: 18 Pages: 3417-3428

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomer ase-Ilalpha in breast cancer cells2009

    • Author(s)
      Rae VA, Klein SR, Agama KK, Toyoda E, Adachi N, Pommier YG, Shacter EB.
    • Journal Title

      Cancer Res

      Volume: 69 Pages: 948-957

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Topoisomerase Ilalpha inhib ition following DNA transfection greatly enhances random integration in a human pie-B lymphocyte cell line2009

    • Author(s)
      Toyoda E, Kurosawa A, Kamekawa H, Adachi N.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 382 Pages: 492-496

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination.2006

    • Author(s)
      Adachi, N., et. al.
    • Journal Title

      DNA Cell Biol 25

      Pages: 19-24

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Journal Article] The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination.2006

    • Author(s)
      Adachi, N. et al.
    • Journal Title

      DNA Cell Biol. 25(1)

      Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-16790058
  • [Journal Article] The human pre-B cell line Nalm-6 is highly proficient in gene targeting by homologous recombination2006

    • Author(s)
      Adachi, N., et. al.
    • Journal Title

      DNA Cell Biol. 25

      Pages: 19-24

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Journal Article] The human pre-B cell line Nalm-6 in highly proficient in gene targeting by homologous recombination.2006

    • Author(s)
      Adachi, N.
    • Journal Title

      DNA Cell Biol. 25

      Pages: 19-24

    • Data Source
      KAKENHI-PROJECT-18570163
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediate DNA damage.2005

    • Author(s)
      Adachi, N.
    • Journal Title

      DNA Cell Biol. 24

      Pages: 388-393

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediated DNA damage.2005

    • Author(s)
      Adachi, N.et al.
    • Journal Title

      DNA Cell Biol. (in press)

    • Data Source
      KAKENHI-PROJECT-16023257
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediated DNA damage.2005

    • Author(s)
      Adachi, N. et al.
    • Journal Title

      DNA Cell Biol. (In press)

    • Data Source
      KAKENHI-PROJECT-16790058
  • [Journal Article] Edivence for a role of vertebrate Rad52 in the repaire of topoisomerase II-mediated DNA damage2005

    • Author(s)
      Adachi, N., Iiizumi, S., Koyama, H.
    • Journal Title

      DNA Cell Biol. 24

      Pages: 388-393

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N. et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 856-861

    • Data Source
      KAKENHI-PROJECT-16790058
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells--Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N. et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Data Source
      KAKENHI-PROJECT-16790058
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 Cells. Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 856-861

    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      Biochem Biophys.Res.Commun. 318

      Pages: 856-861

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells: Implications for the repair of topoisomerase I-mediated DNA damage2004

    • Author(s)
      Adachi, N., So, S., Koyama, H.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 37343-37348

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells : Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Data Source
      KAKENHI-PROJECT-16021247
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells--Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N.et al.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Data Source
      KAKENHI-PROJECT-16023257
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 856-861

    • Data Source
      KAKENHI-PROJECT-16012252
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage2004

    • Author(s)
      Adachi, N., Iiizumi, S., So, S., Koyama, H.
    • Journal Title

      Biochem. Biophys. Res. Commun. 318

      Pages: 856-861

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 856-861

    • Data Source
      KAKENHI-PROJECT-16021247
  • [Journal Article] Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.2004

    • Author(s)
      Adachi, N.et al.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 856-861

    • Data Source
      KAKENHI-PROJECT-16023257
  • [Journal Article] Loss of nonhomologous end-joining confers camptothecin resistance in DT40 cells : Implications for the repair of topoisomerase I-mediated DNA damage.2004

    • Author(s)
      Adachi, N.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 37343-37348

    • Data Source
      KAKENHI-PROJECT-16012252
  • [Journal Article] Genetic interactions between BLM and the nonhomologous end-joining pathway in human cells2004

    • Author(s)
      So, S., Adachi, N., Lieber, M., Koyama, H.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 55433-55442

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase II α2003

    • Author(s)
      Akimitsu, N., Adachi, N., Hirai, H., Hossain, M.S., Hamamoto, H., Kobayashi, M., Aratani, Y.Koyama, H., Sekimizu, K.
    • Journal Title

      Gene Cells 8

      Pages: 393-402

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Hypersensitivity of nonhomologous DNA end-joining mutants to VP-16 and ICRF-193-Imprications for repair of topoisomerase II-mediated DNA damage2003

    • Author(s)
      Adachi, N., Suzuki, H., Iizumi, S., Koyama, H.
    • Journal Title

      J. Biol. Chem. 278

      Pages: 35897-35902

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Model for MLL translocations in therapyrelated leukemia involving topoisomerase Ilbeta mediated DNA strand breaks and gene proximity

    • Author(s)
      DCowell IG, Sondka Z, Smith K, Lee KC, Manville CM, SidorczukLesthuruge M, Rance HA, Padget K, Jackson GH, Adachi N, Austin CA.
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediate DNA damage.

    • Author(s)
      Adachi, N.
    • Journal Title

      DNA Cell Biol. (In press)

    • Data Source
      KAKENHI-PROJECT-15570146
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediated DNA damage.

    • Author(s)
      Adachi, N.
    • Journal Title

      DNA Cell Biol. (in press)

    • Data Source
      KAKENHI-PROJECT-16021247
  • [Journal Article] Evidence for a role of vertebrate Rad52 in the repair of topoisomerase II-mediated DNA damage.

    • Author(s)
      Adachi, N.
    • Journal Title

      DNA Cell Biol. (in press)

    • Data Source
      KAKENHI-PROJECT-16012252
  • [Journal Article] The helicase domain and Cterminus of human RecQL4 facilitate replication elongation on DNA templates damaged by ionizing radiation

    • Author(s)
      Kohzaki M, Chiourea M, Versini G, Adachi N, Takeda S, Gages S, Halazonetis TD.
    • Journal Title

      Carcinogenesis

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Journal Article] Artemis Cterminal region facilitates efficient V(D) J recombination through its interaction with both DNA Ligase IV and DNA-PKcs

    • Author(s)
      Malu S, De loannes P, Kozlov M, Greene M, Francis, D, Hanna M, Pena, J, Escalante CR, Kurosawa A, ErdjumentBromage H, Tempst P, Adachi N, Vezzoni P, Villa A, Aggarwal AK, Certes P.
    • Journal Title

      J Exp Med

      Volume: (in press)

    • Data Source
      KAKENHI-PROJECT-21590066
  • [Patent] 遺伝子ターゲティングベクター及びその利用方法2012

    • Inventor(s)
      足立典隆
    • Industrial Property Rights Holder
      足立典隆
    • Filing Date
      2012-12-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24310149
  • [Patent] 遺伝子ターゲティングベクター及びその利用方法2012

    • Inventor(s)
      足立典隆
    • Industrial Property Rights Holder
      足立典隆
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-12-12
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24659035
  • [Patent] 遺伝子ターゲティングベクター、その作製方法及び利用方法2012

    • Inventor(s)
      足立典隆
    • Industrial Property Rights Holder
      足立典隆
    • Industrial Property Rights Type
      特許
    • Filing Date
      2012-05-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24659035
  • [Patent] 遺伝子ターゲティングベクター, その作製方法及び利用方法2012

    • Inventor(s)
      足立典隆
    • Industrial Property Rights Holder
      足立典隆
    • Filing Date
      2012-05-24
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24310149
  • [Presentation] Functional analysis of human WHSC1 in DNA double-strand break repair2020

    • Author(s)
      足立典隆、他
    • Organizer
      日本環境変異原学会第49回大会
    • Data Source
      KAKENHI-PROJECT-19H01151
  • [Presentation] DNA polymerase theta is essential for alternative end-joining2020

    • Author(s)
      足立典隆、他
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01151
  • [Presentation] Introduction & Defining the mutation signatures of DNA polymerase θ in cancers2020

    • Author(s)
      足立典隆
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01151
  • [Presentation] Role of Human DNA Polymerase θ at Double-Strand Breaks2018

    • Author(s)
      Saito S., Adachi N.
    • Organizer
      The 5th DNA polymerases meeting
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19407
  • [Presentation] Regulatory role of human DNA-PKcs in DNA double-strand break repair2015

    • Author(s)
      Watabe Haruka, Shinta Saito, Aya Kurosawa, Noritaka Adachi
    • Organizer
      BMB2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PROJECT-26740019
  • [Presentation] Gene knockout studies on DNA strand break repair in human cells2007

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      127th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Toyama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Gene knockout studies on DNA strand break repair in human cells2007

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Gene knockout studies on DNA strand break repair in human cells2007

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      127th Annual Meeting of the Pharmaceutical Society of Japan
    • Place of Presentation
      Toyama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Gene knockout studies on DNA strand break repair in human cells2007

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      日本薬学会第127年会
    • Place of Presentation
      富山
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Impact of DSB repair deficiency on damage sensitivity: NHEJ negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      The Salk/Caltech conference on DNA. Replication and Genome Integrity
    • Place of Presentation
      La Jolla (USA)
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Gene knockout studies on DNA double-strand break epair in human cells2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Nonhomologous end-joining negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair.2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      20th IUBMB Int'l and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Nonhomologous end-joining negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      20th IUBMB Int'l and llth FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Gene knockout studies on DNA double-strand break repair in human cells.2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      JCA2006
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Nonhomologous end-joining negatively affects cell survival in the resence of DNA lesions that rely on homoloous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      20th IUBMB Int'l Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Gene knockout studies on DNA double-strand break repair in human cells2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      JCA2006
    • Place of Presentation
      Yokohama
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Impact of DSB repair deficiency on damage sensitivity:NHEJ negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      The Salk/Caltech conference on DNA Replication and Genome Integrity
    • Place of Presentation
      La Jolla,CA,USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Impact of DSB repair deficiency on damage sensitivity: NHEJ negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair.The Salk/Caltech conference on DNA.2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      Replication and Genome Integrity
    • Place of Presentation
      La Jolla (USA)
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Gene knockout studies on DNA double-strand break repair in human cells2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      第65回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • [Presentation] Nonhomologous end-joining negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      20th IUBMB Int'l Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
    • Place of Presentation
      Kyoto
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18590063
  • [Presentation] Impact of DSB repair deficiency on damage sensitivity:NHEJ negatively affects cell survival in the presence of DNA lesions that rely on homologous DNA repair2006

    • Author(s)
      Adachi, N., et. al.
    • Organizer
      The Salk/Caltech conference on DNA Replication and Genome Inteerity
    • Place of Presentation
      La Jolla, CA, USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570163
  • 1.  KOYAMA Hideki (40085626)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 6 results
  • 2.  TAMURA Tomohiko (50285144)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  NISHIYAMA Akira (80589664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Kurosawa Aya (70505867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  IWABUCHI Kuniyoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  YASUI Manabu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  SAJI Tetsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  GRUZ Petr
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  佐々 彰
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  青田 聖恵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  松本 義久
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  橋本 光正
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  能美 健彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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