Kitajima Satoshi 北嶋聡

… Alternative Names

KITAJIMA Satoshi 北嶋聡

北嶋聡

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Researcher Number	30270622
Other IDs
Affiliation (Current)	2022: 国立医薬品食品衛生研究所, 毒性部, 部長
Affiliation (based on the past Project Information) *help	2012: 国立医薬品食品衛生研究所, 安全性生物試験研究センター, 毒性部第五室室長 2012: 国立医薬品食品衛生研究所, 毒性部, 室長 2010 – 2011: 国立医薬品食品衛生研究所, 安全性生物試験研究センター・毒性部第五室, 室長 2010: 国立医薬品食品衛生研究所, 毒性部, 室長 2009: 国立医薬品食品衛生研究所, 毒性部, 主任研究官 … More 2006: National Institute of Health Sciences, Cellular and Molecular Toxicology Division, Section chief, 毒性部・第5室, 室長 2002 – 2006: 国立医薬品食品衛生研究所, 毒性部, 主任研究官 2005: 国立医薬品食品衛生研究所, 毒性部・第4室, 主任研究官 2001 – 2002: 国立医薬品食品衛生研究所, 毒性部・第4室, 主任研究官 1999: 国立医薬品食品衛生研究所, 毒性部, 研究員 Less
Review Section/Research Field	Principal Investigator Developmental biology / Laboratory animal science Except Principal Investigator Developmental biology / Developmental biology / Biological Sciences
Keywords	Principal Investigator 細胞分化 / Mesp1 / 細胞系譜解析 / GFP蛍光 / 心臓・血管 / 循環器 / Cre-loxPシステム / 胚性幹細胞 / 安全性 / 催奇形性 / トキシコゲノミクス / マウス胚 … More Except Principal Investigator … More Mesp2 / 体節形成 / Notchシグナル / 体節時計 / Dll1 / マウス / 遺伝学 / 分子時計 / paraxis / Notchシグナル系 / somitogenesis / Mesp1 / Hesr1 / Hesr2 / Notch signaling / Notchシグナ / 脊椎骨 / Tbx6 / 未分節中胚葉 / L-fng / Hes7 / 分節境界 / D111 / キメラ解析 / Pofut1 / Lunatic Fring / Lunatic Fringe / Notch-YFP / Delta / 前後極性 / ノックアウトマウス / pax遺伝子 / 筋分化 / Mesp2ノックアウトマウス / プレセニリン / 分節化 / 上皮化 / パラキシス / 読めない / rostrocaudal polarity / knockout mice / myogenesis / vetebral column / 心臓形成 / Notchシグナリング / 房室境界 / EphA4 / Ripply2 / hesr1 / hesr2 / GFP / heart formation / segmentation clock / 発生生物学 / パターン形成 / Developmental biology / Genetics / Mouse / Pattern formation Less

Molecular mechanisms of species differences of the thalidomide ‐induced phocomelia by targeting thalidomide‐responsive transcriptome in mouse embryoPrincipal Investigator
- Principal Investigator
  
  KITAJIMA Satoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Institute of Health Sciences
Functional difference between Notch ligands Dll1 and Dll3 in mouse somitogenesis
- Principal Investigator
  
  TAKAHASHI Yu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Health Sciences
The mechanism of somite segmentation with periodic patterning
- Principal Investigator
  
  SAGA Yumiko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Genetics
Molecular genetic analysis of relationship between traveling wave and constant wave of molecular clock in somitogenesis
- Principal Investigator
  
  TAKAHASHI Yu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Health Sciences
Molecular bases underlying cardiogenesis and somitogenesis of mesodermal cells
- Principal Investigator
  
  SAGA Yumiko
- Project Period (FY)
  2002 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Genetics
転写因子Mesplを指標としたマウス心筋・血管内皮前駆細胞の単離と分化の解析Principal Investigator
- Principal Investigator
  
  北嶋聡
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute of Health Sciences
Developmental genetics involved in the mechanism of vertebrate somitogenesis
- Principal Investigator
  
  SAGA Yumiko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Developmental biology
- Research Institution
  Natiomal Institute of Genetics
  National Institute of Health Sciences

All 2012 2011 2010 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Hormone-Disruptive Chemical Contaminants in Food Chapter11 Application of Percellome Toxicogenomics to Food Safety2011
- Author(s)
  J.Kanno, K.Aisaki, K.Igarashi, N.Nakatsu, Y.Kodama, K.Sekita, A.Takagi, S.Kitajima
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-22500398
[Book] Hormone-Disruptive Chemical Contaminants in Food -Chapter11 Application of Percellome Toxicogenomics to Food Safety2011
- Author(s)
  Kanno J, Aisaki K, Igarashi K, Nakatsu N, Kodama Y, Sekita K, Takagi A, Kitajima S
- Publisher
  Royal Society of Chemistry
- Data Source
  KAKENHI-PROJECT-22500398
[Journal Article] Development of Humanized Steroid and Xenobiotic Receptor Mouse by homologous knock-in of the human Steroid and Xenobiotic Receptor Ligand Binding Domain sequence2012
- Author(s)
  Igarashi K, Kitajima S, Aisaki K, Tanemura K, Taquahashi Y, Moriyama N, Ikeno E, Matsuda N, Saga Y, Blumberg B, Kanno J
- Journal Title
  
  J Toxicol Sci
  
  Volume: 37巻 Pages: 373-380
- NAID
  10030126875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500398
[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010
- Author(s)
  Oginuma M, Takahashi Y, Kitajima S, Kiso M, Kanno J, Kimura A, Saga Y
- Journal Title
  
  Development.
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010
- Author(s)
  Masayuki Oginuma, Yu Takahashi, Satoshi Kitajima, Makoto Kiso, Jun Kanno, Akatsuki Kimura, Yumiko Saga
- Journal Title
  
  Development
  
  Volume: 137 Pages: 1515-1522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570215
[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010
- Author(s)
  Oginuma M., Takahashi Y., Kitajima S., Kiso M., Kanno J., Kimura A., Saga Y.
- Journal Title
  
  Development(First 2 authors equal contribution) 137
  
  Pages: 1515-1522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570215
[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation rostral-caudal patterning within a somite2010
- Author(s)
  Masayuki Oginuma, Yu Takahashi, Satoshi Kitajima, Makoto Kiso, Jun Kanno, Akatsuki Kimura, Yumiko Saga
- Journal Title
  
  Development 137
  
  Pages: 1515-1522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570215
[Journal Article] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.2008
- Author(s)
  Yasuhiko Y., Kitajima S., Takahashi Y., Oginuma M., Kagiwada H., Kanno J., Saga Y.
- Journal Title
  
  Development 135
  
  Pages: 3511-3519
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20570215
[Journal Article] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm (PSM) specific enhancer of Mesp.2008
- Author(s)
  Yasuhiko Y, Kitajima S, Takahashi Y, Oginuma M, Kagiwada H, Kanno J, Saga Y
- Journal Title
  
  Development 135
  
  Pages: 3511-9
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation2007
- Author(s)
  Takahashi, Y, Yasuhiko, Y, Kitajima, S, Kannno, J, Saga, Y.
- Journal Title
  
  Developmental Biology 304
  
  Pages: 593-603
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570186
[Journal Article] Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation.2007
- Author(s)
  Takahashi Y, Yasuhiko Y, Kitajima S, Kannno, J, Saga Y
- Journal Title
  
  Dev. Biol. 304
  
  Pages: 593-603
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation2007
- Author(s)
  高橋雄, 安彦行人, 北嶋聡, 菅野純, 相賀裕美子
- Journal Title
  
  Developmental Biology 304
  
  Pages: 593-603
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570186
[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006
- Author(s)
  Yasuhiko Y., Haraguchi S., Kitajima S., Takahashi Y, Kanno J. Saga, Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 103
  
  Pages: 3651-3656
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Mesp1-nonexpressing cells contribute to the ventricular cardiac conduction system.2006
- Author(s)
  Kitajima S, Miyagawa-Tomita S, Inoue T, Kanno J, Saga Y
- Journal Title
  
  Dev Dyn. 235
  
  Pages: 395-402
- Data Source
  KAKENHI-PROJECT-14104024
[Journal Article] Mesp1-nonexpressing cells contribute to the ventricular cardiac conduction system.2006
- Author(s)
  Kitajima S. et al.
- Journal Title
  
  Dev Dyn. 235
  
  Pages: 395-402
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14104024
[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006
- Author(s)
  Yasuhiko Y, Haraguchi S., Kitajima S., Takahashi Y., Jun Kanno J., Saga Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 3651-3656
- Data Source
  KAKENHI-PROJECT-17082010
[Journal Article] Tbx6-mediated Notch signaling controls somite-specific Mesp2 expression.2006
- Author(s)
  Yasuhiko Y, Haraguchi S.Kitajima* S., Takahashi Y., Jun Kanno J., Saga Y.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 103
  
  Pages: 3651-3656
- Data Source
  KAKENHI-PROJECT-14104024
[Journal Article] Differential contributions of Mesp1 and Mesp2 to the epithelialization and rostro-caudal patterning of somites2005
- Author(s)
  Takahashi Y, Kitajima S, Inoue T, Kannno N, Saga Y
- Journal Title
  
  Development 132
  
  Pages: 787-796
- Data Source
  KAKENHI-PROJECT-14104024
[Journal Article] Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.2004
- Author(s)
  Ishikawa A, Kitajima S. et al.
- Journal Title
  
  Mechanism of Development 21
  
  Pages: 1443-1453
- Data Source
  KAKENHI-PROJECT-14104024
[Journal Article] Appropriate suppression of Notch signaling by Mesp factors is essential for stripe pattern formation leading to segment boundary formation.2004
- Author(s)
  Takahashi Y, Yasuhiko Y, Kitajima S, Kanno J, Saga Y
- Journal Title
  
  Dev.Biol 304
  
  Pages: 593-603
- Data Source
  KAKENHI-PROJECT-14104024
[Presentation] Percellome 網羅的定量的トキシコゲノミクス2012
- Author(s)
  北嶋聡、高橋祐次、五十嵐勝秀、相崎健一、菅野純
- Organizer
  平成24 年度公益社団法人日本実験動物学会維持会員懇談会
- Place of Presentation
  東京(中央大学駿河台記念館)
- Year and Date
  2012-11-16
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] パーセローム(Percellome)法を用いた定量的トランスクリプトミクスによる遺伝子発現ネットワーク描出による毒性解析の試み2011
- Author(s)
  菅野純、相崎健一、北嶋聡
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] パーセローム(Percellome)法を用いた定量的トランスクリプトミクスによる遺伝子発現ネットワーク描出による毒性解析の試み2011
- Author(s)
  菅野純、相崎健一、北嶋聡
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮市(栃木県総合文化センター)
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] Percellomeプロジェクト・オンライン解析システム2011
- Author(s)
  相崎健一、五十嵐勝秀、種村健太郎、安彦行人、高橋祐次、高木篤也、北嶋聡、菅野純
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  パシフィコ横浜会議センター
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] Percellome プロジェクト・オンライン解析システム2011
- Author(s)
  相崎健一、五十嵐勝秀、種村健太郎、安彦行人、高橋祐次、高木篤也、北嶋聡、菅野純
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜(パシフィコ横浜会議センター)
- Year and Date
  2011-07-13
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] Percellome発生トキシコゲノミクスの進捗2010
- Author(s)
  北嶋聡
- Organizer
  第37回日本トキシコロジー学会学術年会
- Place of Presentation
  沖縄(沖縄コンベンションセンター)
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] Percellome発生トキシコゲノミクスの進捗2010
- Author(s)
  北嶋聡
- Organizer
  第37回日本トキシコロジー学会学術年会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22500398
[Presentation] Novel mouse Delta-like 1 (Dll1) alleles yield insights into involvement of Notch signal in segmentation of vertebrae.2008
- Author(s)
  高橋雄,北嶋聡,安彦行人,菅野純,相賀裕美子
- Organizer
  BMB2008
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20570215
[Presentation] Overexpression of Delta-like 3 (Dll3) in the presomitic mesoderm causes defects in the axial skeletal formation.2008
- Author(s)
  高橋雄,北嶋聡,安彦行人,菅野純,相賀裕美子
- Organizer
  第3回Notch研究会
- Place of Presentation
  三島
- Data Source
  KAKENHI-PROJECT-20570215
[Presentation] Delta-like 3 (Dll3) does not substitute for Delta-like 1 (Dll1) in somitogenesis in vivo but modulates Dll1/Notch signaling in the posterior PSM.2008
- Author(s)
  高橋雄,北嶋聡,安彦行人,菅野純,相賀裕美子
- Organizer
  第41回日本発生生物学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-20570215
[Presentation] 体節形成に関わる転写因子Mesp2の発現制御における転写因子Tbx6の役割2006
- Author(s)
  安彦行人, 原口清輝, 北嶋聡, 高橋雄, 菅野純, 相賀裕美子
- Organizer
  日本発生生物学会第39回大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] 体節形成におけるストライプパターンの形成には未分節中胚葉前方におけるNotchシグナルのネガティブフィードバックが本質的に重要である.2005
- Author(s)
  高橋雄, 北嶋聡, 菅野純, 相賀裕美子
- Organizer
  日本発生生物学会第38回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-17082010
[Presentation] Percellome網羅的定量的トキシコゲノミクス
- Author(s)
  北嶋聡
- Organizer
  平成24年度公益社団法人日本実験動物学会維持会員懇談会
- Place of Presentation
  中央大学　駿河台記念館
- Invited
- Data Source
  KAKENHI-PROJECT-22500398

1. TAKAHASHI Yu (60321858)

# of Collaborated Projects: 4 results

# of Collaborated Products: 19 results
2. YASUHIKO Yukuto (40370944)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. SAGA Yumiko (50221271)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
4. KOKUBO Hiroki (10270480)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MISTUI Kaoru (40324975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KANNO Jun (90186172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. TAKAGI Atsuya (00179417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kitajima Satoshi 北嶋 聡

KITAJIMA Satoshi 北嶋 聡

北嶋 聡

Research Projects

Research Products

Co-Researchers

Molecular mechanisms of species differences of the thalidomide ‐induced phocomelia by targeting thalidomide‐responsive transcriptome in mouse embryoPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional difference between Notch ligands Dll1 and Dll3 in mouse somitogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of somite segmentation with periodic patterning

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular genetic analysis of relationship between traveling wave and constant wave of molecular clock in somitogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular bases underlying cardiogenesis and somitogenesis of mesodermal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写因子Mesplを指標としたマウス心筋・血管内皮前駆細胞の単離と分化の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Developmental genetics involved in the mechanism of vertebrate somitogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Hormone-Disruptive Chemical Contaminants in Food Chapter11 Application of Percellome Toxicogenomics to Food Safety2011

Author(s)

Publisher

Data Source

[Book] Hormone-Disruptive Chemical Contaminants in Food -Chapter11 Application of Percellome Toxicogenomics to Food Safety2011

Author(s)

Publisher

Data Source

[Journal Article] Development of Humanized Steroid and Xenobiotic Receptor Mouse by homologous knock-in of the human Steroid and Xenobiotic Receptor Ligand Binding Domain sequence2012

Author(s)

Journal Title

NAID

Data Source

[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010

Author(s)

Journal Title

Data Source

[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010

Author(s)

Journal Title

Data Source

[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation and rostral-caudal patterning within a somite.2010

Author(s)

Journal Title

Data Source

[Journal Article] The oscillation of Notch activation, but not its boundary, is required for somite border formation rostral-caudal patterning within a somite2010

Author(s)

Journal Title

Data Source

[Journal Article] Functional importance of evolutionally conserved Tbx6 binding sites in the presomitic mesoderm-specific enhancer of Mesp2.2008

Author(s)

Journal Title

Kitajima Satoshi 北嶋聡

KITAJIMA Satoshi 北嶋聡

北嶋聡