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Fujita Masatoshi  藤田 雅俊

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FUJITA Masatoshi  藤田 雅俊

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Researcher Number 30270713
Other IDs
Affiliation (Current) 2025: 九州大学, 薬学研究院, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 九州大学, 薬学研究院, 教授
2012 – 2016: 九州大学, 薬学研究科(研究院), 教授
2010 – 2011: 九州大学, 薬学研究院, 教授
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, ウイルス部, 室長
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, ウイルス部, 室長 … More
2005 – 2008: 国立がんセンター(研究所及び東病院臨床開発センター), ウイルス部, 室長
2005: 国立がんセンター研究所, ウィルス部, 室長
2005: National Cancer Center Reseach Institute, Virology Division, General Manager, ウイルス部, 室長
2004: 国立がんセンター(研究所), ウイルス部, 室長
2003: 国立がんセンター研究所, ウイルス部, 室長
2002 – 2003: 国立がんセンター, ウイルス部, 室長
2000 – 2002: 愛知県がんセンター, 腫瘍ウイルス学部, 主任研究員
1998 – 2000: 愛知県がんセンター, ウイルス部, 主任研究員
1996 – 1998: 愛知県がんセンター研究所, 研究員
1997: 愛知県がんセンター, ウイルス部, 研究員
1997: 愛知県がんセンター研, ウイルス部, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 43050:Genome biology-related / Molecular biology / Virology / Biological Sciences / Functional biochemistry / Tumor biology / Molecular biology
Except Principal Investigator
Biological Sciences / Virology
Keywords
Principal Investigator
細胞周期 / DNA複製 / クロマチン / Cdt1 / MCMタンパク / CDC6タンパク / ORCタンパク / 複製開始複合体 / ヒト細胞 / ORC … More / CDC6 / MCM / クロマチン免疫沈降法 / EBNA-1 / 複製開始点 / ヒストンシャペロン / GRWD1 / SNF2H / グロビン遺伝子 / MCM蛋白 / CDC6蛋白 / ORC蛋白 / DNA複製開始制御 / 染色体不安定性 / 細胞周期制御 / 複製フォークとDNA-蛋白質複合体衝突 / RAD52 / SLX4 / 複製フォークとDNA-タンパク質複合体衝突 / 複製ストレス応答分子機構 / Chromatin immunoprecipitation / Globin locujs / MCM protein / CDC6 protein / ORC protein / Cell cycle / Regulation for DNA replication initiation / Human cells / Human ORC protein / Human CDC6 protein / Human MCM protein / DNA replication / EB virus / ヒトORC1タンパク / ヒトORCタンパク / ヒトCDC6タンパク / ヒトMCMタンパク / EBウイルス / 次世代シークエンサー / ゲノムワイド解析 / クロマチン制御 / リボソーム蛋白質 / RP / EDDユビキチンリガーゼ / 転写 / Pura / EDD / Ribosomal protein / 核小体ストレス / がん遺伝子 / MDM2 / RPL11 / p53 / 新規がん診断法 / 新規がん遺伝子 / ATM / ライセンシング制御 / 複製開始制御 / 次世代シークエンシング / ヒストンシャペロ / 染色体 / 遺伝子 / ゲノム / 分子生物学 / TRF2 / テロメア / タンパク質分解制御 / 複製チェックポイント / ATR / CRL4ユビキチンリガーゼ / クロマチンリモデリング / 染色体安定性 / 染色体DNA複製 / Geminin / CDK / DNA障害チェックポイント系 / geminin / 核アクチン / クロマチンリモデリング複合体 / 発癌 / Cdk / サイクリン / ヒトグロビン領域 / ホルマリンクロスリンク / ヒト体細胞 … More
Except Principal Investigator
DNA複製 / DNAポリメラーゼ / ゲノム / 酵素 / 癌 / 感染症 / ウイルス / Epstein-Barr Virus / Epstein-Barrウイルス / MCM / 細胞周期 / protein-protein interaction / primase / helicase / Epstein-Barr virus / DNA replication / プライマーゼ / ヘリカーゼ / Clamp-Clamp loader / Nuclear Matrix Attachment / Cyclin-dependent kinase / Cdc7 kinase / MCM complex / prereplicative complex / E2F transcription factor / G1-S transition / マウス胚性幹細胞 / MCM2 / Cdc7-ASKキナーゼ / ES細胞 / DNAヘリカーゼ / Cdcキナーゼ / DNA複製開始 / リン酸化 / G1-S期移行 / クランプ=クランプローダー / 核マトリックス付着 / サイクリン依存性キナーゼ / Cdc7キナーゼ / MCMタンパク質 / DNA複製前複合体 / E2F転写因子 / G1-S期以降 / T細胞 / 胃がん / 蛋白質間相互作用 / CDC6 / 蛋白質-蛋白質相互作用 / EBV / p16^<INK4a> / ヒトパピローマウイルス(HPV) / トランスフォーメーション / 不死化 / TERT / E7 / E6 / ヒトパピローマウイルス / SSB / ウイルス発癌 / E6蛋白 / hDLG / トランスフォーメイション / PDZドメイン / ヒトパピローマウイルス16型 / E2F-1 / 蛋白質リン酸化 / ライセンシング因子 / S期導入因子 / 複製開始点結合因子 / PCNA / ORC / 染色体構造 / DNA修復 / クロマチン集合 / DNAメチル転移酵素 / S期 / PCNA結合タンパク質 Less
  • Research Projects

    (23 results)
  • Research Products

    (51 results)
  • Co-Researchers

    (25 People)
  •  複製フォークとDNA-蛋白質複合体衝突により惹起される複製ストレス応答機構の解明Principal Investigator

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43050:Genome biology-related
    • Research Institution
      Kyushu University
  •  ゲノムワイド解析による複製開始複合体形成制御とクロマチン制御連携の解明Principal Investigator

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Elucidation of novel functions of GRWD1, a multifunctional protein with histone chaperone activityPrincipal Investigator

    • Principal Investigator
      Fujita Masatoshi
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      Kyushu University
  •  Novel function of ATM for genome maintenance: Regulation of cell cycle factors without chromosomal damagePrincipal Investigator

    • Principal Investigator
      FUJITA Masatoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Kyushu University
  •  Analysis of GRWD1, a novel histone-binding protein involved in chromosomal replication initiation and segregationPrincipal Investigator

    • Principal Investigator
      FUJITA Masatoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Molecular biology
    • Research Institution
      Kyushu University
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  Molecular mechanisms for pre-replication complexes assembly and its implication in chromosomal stability in mammalian cellsPrincipal Investigator

    • Principal Investigator
      FUJITA Masatoshi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  EBウイルス潜伏感染機構とウイルス増殖感染機構の解析

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  EBウイルス感染細胞内におけるウイルスゲノム複製及び保持機構の解析

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  ヒトパピローマウイルスによる発がん機構の解析

    • Principal Investigator
      清野 透
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  EBウイルス陽性がん細胞内におけるウイルスゲノム複製及び保持機構の解析

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  EBウイルス感染細胞内におけるウイルスゲノム複製及び保持機構の解析

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  複製複合体の形成とその制御機構の解析Principal Investigator

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
      Aichi Cancer Center Research Institute
  •  細胞内での蛋白-DNA及び蛋白-蛋白相互作用の同定によるヒトゲノム複製蛋白の解析Principal Investigator

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  From G1 regulators to Replication machinery

    • Principal Investigator
      MASAI Hisao
    • Project Period (FY)
      2000 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  Molecular basis for Epstein-Barr virus genome DNA replication

    • Principal Investigator
      TSURUMI tatsuya
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Division of Virology Aichi Cancer Center Research Institute
  •  Analysis for spatiotemporal regulation of DNA replication intiation proteins on human globin loci.Principal Investigator

    • Principal Investigator
      FUJITA Masatoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Aichi Cancer Center
  •  ヒトDNA複製開始反応関連蛋白質が結合しているゲノムDNA領域の同定Principal Investigator

    • Principal Investigator
      藤田 雅俊
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Molecular Mechanism of Epstein-Barr virus DNA replication in viral infected tumors and cellular immunity for viral associated cancers

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Aichi Cancer Center Research Institute
  •  DNA鎖合成装置のモデル系:EBV複製フォークで働く蛋白質群の機能解析

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Analysis of the interaction between EB viral EBNA-1 protein and cellular proteins involved in the initiation step of host DNA replicationPrincipal Investigator

    • Principal Investigator
      FUJITA Masatoshi
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center
  •  高発癌性粘膜型ヒトパピローマウイルスの発癌蛋白、E6のC末端モチーフの生物活性

    • Principal Investigator
      平岩 厚郎
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  DNA鎖合成装置のモデル系:ローリングサークル型複製伸長を担う蛋白質群の機能解析

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Aichi Cancer Center Research Institute
  •  p21によるPCNAの機能制御と細胞のがん化

    • Principal Investigator
      TSURIMOTO Toshiki
    • Project Period (FY)
      1996 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Nara Institute of Science and Technology

All 2023 2022 2016 2011 2010 2009 2008 2007 2006 2004 2002 2000 Other

All Journal Article Presentation Book Patent

  • [Book] 蛋白質核酸酵素(正井久雄、升方久夫、釣本敏樹、仁木宏典、篠原彰編集, 染色体動態制御における複製開始複合体因子の新たな機能, 増刊号「染色体サイクル」)2009

    • Author(s)
      藤田雅俊.
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Book] Encylopedic Reference of Genomics and Proteomics in Molecular Medicine(edited by Ganten, D. and Ruckpaul, K., DNA Replication Initiation.).2006

    • Author(s)
      Fujita M.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Book] DNA Replication Initiation; in Encyclopedic References of Genomics and Proteomics in Molecular Medicine2006

    • Author(s)
      Masatoshi Fujita
    • Publisher
      Springer-Verlag, Berlin Heidelberg & New York
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Book] DNA Replication Initiation ; in Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine

    • Author(s)
      Masatoshi Fujita
    • Publisher
      Springer-Verlag, Heidelberg (In press)
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Book] DNA Replication Initiation ; in Encyclopedic References of Genomics and Proteomics in Molecular Medicine

    • Author(s)
      Masatoshi Fujita
    • Publisher
      Springer-Verlag, Heidelberg(In press)
    • Data Source
      KAKENHI-PROJECT-12141204
  • [Journal Article] Microscopic Detection of DNA Synthesis in Early Mitosis at Repetitive lacO Sequences in Human Cells2022

    • Author(s)
      Yoshida Kazumasa、Ishimoto Riko、Fujita Masatoshi
    • Journal Title

      BIO-PROTOCOL

      Volume: 12 Issue: 17

    • DOI

      10.21769/bioprotoc.4504

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Journal Article] Chromatin remodeler Sucrose Non-Fermenting 2Homolog(SNF2H) is recruited onto DNAreplication origins through interaction with Cdc10 protein-dependent transcript 1(Cdt1) and promotes pre-replication complex formation2011

    • Author(s)
      Sugimoto, N., Yugawa, T., Iizuka, M., Kiyono, T. & Fujita, M.
    • Journal Title

      J. Biol. Chem

      Volume: 286 Pages: 39200-39210

    • Data Source
      KAKENHI-PROJECT-21370084
  • [Journal Article] CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells.2010

    • Author(s)
      Yoshida K, Sugimoto N, Iwahori S, Yugawa T, Narisawa-Saito M, Kiyono T, Fujita M.
    • Journal Title

      J. C e l l S c i. 123

      Pages: 225-235

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] CDC6interaction with ATR regulates activation ofa replication checkpoint in higher eukaryotic cells2010

    • Author(s)
      Yoshida, K., Sugimoto, N., Iwahori, S., Yugawa, T., Narisawa-Saito, M., Kiyono, T. & Fujita
    • Journal Title

      J. Cell Sci

      Volume: 123 Pages: 225-235

    • Data Source
      KAKENHI-PROJECT-21370084
  • [Journal Article] Redundant and differential regulation of multiple licensing factors ensures prevention of rereplication in normal human cells.2009

    • Author(s)
      Sugimoto N, Yoshida K, Tatsumi Y, Yugawa T, Narisawa-Saito M, Waga S, Kiyono T, Fujita M.
    • Journal Title

      J. C e l l S c i. 122

      Pages: 1184-1191

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Redundant and differential regulation of multiple licensing factors ensures prevention of rereplication in normal human cells2009

    • Author(s)
      Sugimoto, N., Yoshida, K., Tatsumi, Y., Yugawa, T., Narisawa-Saito, M., Waga, S., Kiyono, T. & Fujita, M.
    • Journal Title

      J. Cell Sci

      Volume: 122 Pages: 1184-1191

    • Data Source
      KAKENHI-PROJECT-21370084
  • [Journal Article] Coenzyme Q10 as a potent compound that inhibits Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Takakusagi Y, Yonezawa Y, Mizuno T, Yanagi K, Imamoto N, Sugawara F, Sakaguchi K, Yoshida H, Fujita M.
    • Journal Title

      B i o c h i m. B i o p h y s. A c t a. 1780

      Pages: 203-213

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.2008

    • Author(s)
      Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa-Saito M, Kiyono T, Ohta S, Obuse C, Fujita M.
    • Journal Title

      G e n e s C e l l s 13

      Pages: 1045-1059

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Identification of novel human Cdt1-binding proteins by a proteomics approach: Proteolytic regulation by APC/CCdh1.2008

    • Author(s)
      Sugimoto N, Kitabayashi I, Osano S, Tatsumi Y, Yugawa T, Narisawa-Saito M, Matsukage A, Kiyono T, Fujita, M.
    • Journal Title

      M o l. B i o l. C e l l 19

      Pages: 1007-1021

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] The inhibitory action of SQDG (sulfoquinovosyl diacylglycerol) from spinach on Cdt1-geminin interaction.2008

    • Author(s)
      Mizushina Y, Takeuchi T, Hada T, Maeda N, Sugawara F, Yoshida H, Fujita M.
    • Journal Title

      B i o c h i m i e 90

      Pages: 947-956

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.2006

    • Author(s)
      Tatsumi Y, Sugimoto N, Yugawa T, Narisawa-Saito M, Kiyono T, Fujita M.
    • Journal Title

      J. C e l l S c i. 119

      Pages: 3128-3140

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] wo E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.2006

    • Author(s)
      Nishitani H, Sugimoto N, Roukos V, Nakanishi Y, Saijo M, Obuse C, Tsurimoto T, Nakayama K-I, Nakayama K, Fujita M, Lygerous Z, Nishimoto T.
    • Journal Title

      E M B O J. 25

      Pages: 1126-1136

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Cdt1 revisited : complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.2006

    • Author(s)
      Masatoshi Fujita
    • Journal Title

      Cell Div. 1

      Pages: 22-22

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.2006

    • Author(s)
      Fujita M.
    • Journal Title

      C e l l D i v. 1

      Pages: 22-22

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.2004

    • Author(s)
      Sugimoto, N., Tatsumi, Y., Tsurumi, T., Matsukage, A., Kiyono, T., Nishitani, H, Fujita, M.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 19691-19697

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Journal Article] Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.2004

    • Author(s)
      Sugimoto, N., Tatsumi, Y., Tsurumi, T., Matsukage, A., Kiyono, T., Nishitani, H., Fujita, M.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 19691-19697

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Journal Article] Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding.2004

    • Author(s)
      Sugimoto N, Tatsumi Y, Tsurumi T, Matsukage A, Kiyono T, Nishitani H, Fujita M.
    • Journal Title

      J. B i o l. C h e m. 279

      Pages: 19691-19697

    • Data Source
      KAKENHI-PROJECT-17080013
  • [Journal Article] Nuclear organization of DNA replication initiation proteins in mammalian cells.2002

    • Author(s)
      Fujita, M., Ishimi, Y., Nakamura, H., Kiyono, T, Tsurumi, T.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 10354-10361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Journal Article] Nuclear organization of DNA replication initiation proteins in mammalian cells.2002

    • Author(s)
      Fujita, M., Ishimi, Y., Nakamura, H., Kiyono, T., Tsurumi, T.
    • Journal Title

      J.Biol.Chem 227

      Pages: 10354-10361

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Journal Article] CDK2-dependent and-independent pathways in E2F-mediated S phase induction.2000

    • Author(s)
      Arata, Y., Fujita, M., Ohtani, K., Kijima, S, Kato, J-Y.
    • Journal Title

      J.Biol.Chem. 275

      Pages: 6337-6345

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Journal Article] CDK2-dependent and-independent pathways in E2F-mediated S phase induction.2000

    • Author(s)
      Arata, Y., Fujita, M., Ohtani, K., Kijima, S., Kato, J-Y.
    • Journal Title

      J.Biol.Chem. 275

      Pages: 6337-6345

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12141101
  • [Patent] G2/M期停止及び細胞死を誘導するベンゾヒドラジド誘導体2011

    • Inventor(s)
      藤田雅俊、大嶋孝志、森本浩之
    • Industrial Property Rights Holder
      九州大学
    • Industrial Property Number
      2011-234309
    • Filing Date
      2011-10-25
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Patent] 抗癌性物質のスクリーニング方法2006

    • Inventor(s)
      藤田雅俊, 水品善之
    • Industrial Property Rights Holder
      国立がんセンター・ヒューマンサイェンス振興財団
    • Industrial Property Number
      2006-281754
    • Filing Date
      2006-10-16
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Patent] 抗癌性物質のスクリーニング方法2006

    • Inventor(s)
      藤田雅俊、水品善之
    • Industrial Property Rights Holder
      財団法人ヒューマンサイエンス振興財団
    • Industrial Property Number
      2006-281754
    • Filing Date
      2006-10-16
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] ヒト染色体上のlacO-LacI複合体に対する複製ストレス応答におけるSLX4の集積機構の解析2023

    • Author(s)
      岡野 拓真、藤井 純平、松村 友輝、吉田 和真、勝木 陽子、藤田 雅俊
    • Organizer
      第46回日本分子生物学会年会ポスターセッション
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] 蛋白質核酸複合体障害物により誘導される複製ストレスに対するSLX4-XPF-ATRを介したDNAダメージ応答におけるRAD52の役割2023

    • Author(s)
      藤田 雅俊、勝木 陽子、吉田 和真
    • Organizer
      第46回日本分子生物学会年会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] ヒト染色体上のlacO-LacI複合体に対する複製ストレス応答におけるRAD52の機能解析2023

    • Author(s)
      松下 航世、成松 康貴、吉田 和真、勝木 陽子、藤田 雅俊
    • Organizer
      第46回日本分子生物学会年会ポスターセッション
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] ヒト染色体上における内因性複製ストレス誘導モデルを用いた修復因子SLX4-XPF複合体の局在制御機構2023

    • Author(s)
      勝木 陽子、岡野 拓真、藤井 純平、松村 友輝、吉田 和真、藤田 雅俊
    • Organizer
      第46回日本分子生物学会年会シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] 家族性乳癌を抑制する分子ネットワークが制御するゲノムストレス応答機構2022

    • Author(s)
      勝木陽子、高田穰、藤田雅俊
    • Organizer
      第81回 日本癌学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] ヒト染色体上のlacO-LacI複合体に対する複製ストレス応答機構におけるSLX4-XPF複合体の集積メカニズムの解析2022

    • Author(s)
      藤井純平、松村友輝、吉田和真、東寅彦、白石都、勝木陽子、藤田雅俊
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] 複製とカップルしたDNA損傷修復におけるSLX4のユビキチン化経路を介した制御機構の解析2022

    • Author(s)
      勝木陽子、安倍昌子、岡野拓真、藤井純平、白石都、西野耕平、小迫英尊、髙田穰、藤田雅俊
    • Organizer
      第45回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K23866
  • [Presentation] GRWD1 counteracts p53 via the RPL11-MDM2 pathway and promotes tumorigenesis2016

    • Author(s)
      Fujita M. et al.
    • Organizer
      10th 3R International Symposium
    • Place of Presentation
      ホテル一畑(松江市)
    • Year and Date
      2016-11-13
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25291027
  • [Presentation] GRWD1はRPL11-MDM2経路を介してp53を抑制し細胞がん化を促進する2016

    • Author(s)
      藤田雅俊ら
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-25291027
  • [Presentation] The Cdt1-binding protein GRWD1 is a novel histone chaperone involved in replication licensing.2011

    • Author(s)
      Sugimoto, N., Yasukouchi, S., Watanabe, S., Kiyono, T., Kurumizaka, H. & Fujita, M.
    • Organizer
      第34回日本分子生物学会年会ワークショップ
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-16
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] 複製開始複合体形成に関与しているCdt1結合性ヒストン制御蛋白質2010

    • Author(s)
      藤田雅俊
    • Organizer
      大阪大学蛋白質研究所セミナー「ゲノム機能の記憶の成立機序とその制御」
    • Place of Presentation
      大阪大学蛋白質研究所
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] A novel function of ATM : regulation of Cdt1 during the S phase2010

    • Author(s)
      Masatoshi Fujita
    • Organizer
      Biochemistry and Molecular Biology 2010, Symposium
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] A chromatin remodeler SNF2H is involved in pre-RC formation and Cdt1-induced checkpoint activation.2009

    • Author(s)
      Sugimoto N, Waga S, Kiyono T, Fujita, M.
    • Organizer
      K e y s t o n e S y m p o s i a " T e l o m e r e B i o l o g y a n d D N A R e p a i r"
    • Place of Presentation
      Ashmore, Queensland, Australia.
    • Year and Date
      2009-10-11
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells2009

    • Author(s)
      Yoshida, K., Iwahori, S., Kiyono, T. & Fujita, M.
    • Organizer
      Keystone Symposia"Telomere Biology and DNA Repair"
    • Place of Presentation
      Ashmore, Queensland, Australia
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] 正確にゲノムを倍加させる:複製開始因子Cdt1の分解制御機構の解明と抗がん剤開発への応用2009

    • Author(s)
      藤田雅俊
    • Organizer
      福井大学大学院工学研究科、招請研究セミナー
    • Place of Presentation
      福井
    • Year and Date
      2009-05-26
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] 正確にゲノムを倍加させる:複製開始因子Cdt1の分解制御機構の解明と抗がん剤開発への応用2009

    • Author(s)
      藤田雅俊
    • Organizer
      福井大学大学院工学研究科、招請研究セミナー
    • Place of Presentation
      福井
    • Year and Date
      2009-05-26
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells.2009

    • Author(s)
      Fujita M.
    • Organizer
      I n t e r n a t i o n a l S y m p o s i u m o n C h r o m o s o m e C y c l e a n d G n o m e D y n a m i c s.
    • Place of Presentation
      Nasu, Japan.
    • Year and Date
      2009-11-11
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] CDC6 interaction with ATR regulates activation of areplication checkpoint in higher eukaryotic cells2009

    • Author(s)
      Masatoshi Fujita
    • Organizer
      International Symposium on "Chromosome Cycle and genome dynamics"
    • Place of Presentation
      Nasu, Tochigi
    • Year and Date
      2009-11-11
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] A chromatin remodeler SNF2H is involved in pre-RC formation and Cdt1-induced checkpoint activation2009

    • Author(s)
      Sugimoto, N., Waga, S., Kiyono, T. & Fujita, M.
    • Organizer
      Keystone Symposia "Telomere Biology and DNA Repair"
    • Place of Presentation
      Ashmore, Queensland, Australia
    • Data Source
      KAKENHI-PROJECT-21370084
  • [Presentation] Cdk phosphorylation-dependent interaction of human CDC6 with ATR is involved in G2/M checkpoint response.2008

    • Author(s)
      Yoshida K, Kiyono T, Fujita M.
    • Organizer
      T h e M e e t i n g o n D N A R e p l i c a t i o n a n d G e n o m e I n t e g r i t y a t S a l k I n s t i t u t e
    • Place of Presentation
      La Jolla, USA.
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres and telomere homeostasis.2007

    • Author(s)
      Tatsumi Y, Ezura K, Yoshida K, Kiyono T, Ohta S, Obuse C, Fujita, M.
    • Organizer
      C o l d S p r i n g H a r b o r L a b o r a t o r y M e e t i n g o n E u k a r y o t i c D N A R e p l i c a t i o n & G e n o m e M a i n t e n a n c e
    • Place of Presentation
      Cold Spring Harbor, USA.
    • Year and Date
      2007-09-06
    • Data Source
      KAKENHI-PROJECT-17080013
  • [Presentation] Genome-wide relationship between pre-replication complex formation and chromatin status

    • Author(s)
      Masatoshi Fujita
    • Organizer
      The 9th 3R Symposium
    • Place of Presentation
      Gotemba Kogen Hotel
    • Year and Date
      2014-11-17 – 2014-11-21
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-26114713
  • 1.  TSURUMI Tatsuya (90172072)
    # of Collaborated Projects: 10 results
    # of Collaborated Products: 0 results
  • 2.  SUGAYA Yutaka
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  YOKOYAMA Naoaki (80301802)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  TSURIMOTO Toshiki (30163885)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OHTANI Kiyoshi (30201974)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 6.  MURAKAMI Yota (20260622)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  MASAI Hisao (40229349)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  NAKASU Shou (50198107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  KUZUSHIMA Kiyotaka (30311442)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  小布施 力史 (00273855)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  清野 透 (10186356)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  中村 普武 (30109938)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NISITANI Hidbo (40253455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  MIZUNO Takeshi (30281629)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  WAGA Shou (60222402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 16.  加藤 順也 (00273839)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  秋山 昌広 (80273837)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  平岩 厚郎 (80238336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  石橋 正英 (70029776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  松本 義也 (80239128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  山下 依子 (90303643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  大黒 徹 (80291409)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  大坪 素秋 (10211799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  佐藤 憲子 (70280956)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  KIM Jung?Min
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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