Tokumoto Toshinobu 徳元俊伸

… Alternative Names

TOKUMOTO Toshinobu 徳元俊伸

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Researcher Number	30273163
Other IDs
External Links
Affiliation (Current)	2025: 静岡大学, 理学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 静岡大学, 創造科学技術大学院, 教授 2018: 静岡大学, 創造科学技術大学院, 教授 2014 – 2017: 静岡大学, 理学部, 教授 2013: 静岡大学, その他の研究科, 教授 2004 – 2006: SHIZUOKA UNIVERSITY, FACULTY OF SCIENCE, ASSOCIATE PROFESSOR, 理学部, 助教授 … More 2002 – 2003: 静岡大学, 理学部, 講師 2001: SHIZUOKA UNIVERSITY, FACULTY OF SCIENCE, ASSOCIATE PROFESSOR, 理学部, 助教授 2000 – 2001: 静岡大学, 理学部, 助手 1998: 静岡大学, 理学部・生物地球環境科学科, 助手 1998: 静岡大学, 理学部生物地球環境科学科, 助手 1997 – 1998: 静岡大学, 理学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 44040:Morphology and anatomical structure-related / Morphology/Structure / Natural medicines / Developmental biology / 動物生理・代謝 Except Principal Investigator Laboratory animal science / Laboratory animal science
Keywords	Principal Investigator ステロイド膜受容体 / 卵成熟 / 排卵 / 遺伝子発現 / タンパク質分解 / プロテアソーム / サイクリン / ゲノム編集 / 天然活性物質 / スクリーニング法 … More / ホルモン受容体 / 蛋白質 / サンゴ礁 / モーリシャス / 天然ホルモン活性物質 / ホルモン活性物質 / 天然資源 / goldfish / endocrine disrupting chemicals / DES / diethylstilbestrol / oocyte maturation / mPRα / membrane progestin receptor alpha / 内分泌かく乱物質 / mPR / プロゲスチン膜受容体 / キンギョ / 内分泌かく乱化学物質 / プロゲスチン / ステロイドホルモン / 膜受容体 / CDNAクローニング / 点突然変異体 / ユビキチン化 / cDNA クローニング … More Except Principal Investigator 始原生殖細胞 / マウス / Primordial germ cells / PTEN / Testicular teratomas / 染色体マッピング / Apoptosis / Gonadal somatic cells / Germ-cell growth factor / Mouse embryo / ter (teratoma) gene / アポトーシス / ter変異遺伝子 / ter(teratoma) / 奇形腫原因遺伝子 / 精巣性奇形腫 / 生殖細胞欠損 / ter遺伝子 / TERF / 細胞増殖因子 / Totipotency / Chromosome mapping / Teratoma candidate / KO mouse / Mouse / 精子形成 / 精巣性奇形腫(テラトーマ) / 生殖細胞増殖 / 生殖細胞特異遺伝子 / マッピング / 奇形腫(テラトーマ) / 分化全能性 / 遺伝子改変マウス / 奇形腫高発系 / ett1 (experimental testicular teratomas 1) gene / インプリンティング / 原因遺伝子 / 生殖細胞特異抗原 / 胎仔精巣 / テラトーマ原因遺伝子 / 生殖巣体細胞 / PGC増殖因子 / ett1(experimental testicular teratomas1) / マウス胚 / Conditioned medium / Germ cell deficiency / 生殖細胞培養 / コンデイションメデイウム / 遺伝子クローニング / 精巣体細胞 / コンデイシヨンドメディウム / 胎仔生殖巣体細胞 / コンディションドメデイウム / PGC欠損 / 増殖因子 / 貧血 / 不妊 / 奇形腫高発系マウス / 生殖細胞増殖因子 / 遺伝子 / 幹細胞増殖因子 / 単為発生卵 / 生殖細胞 / コンジェニック系統 / 卵巣性奇形腫 / 奇形腫(テラトーマ)高発系マウス / SLF / コンディションドメディウム Less

Functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator
- Principal Investigator
  
  徳元俊伸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Shizuoka University
Functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator
- Principal Investigator
  
  Tokumoto Toshinobu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44040:Morphology and anatomical structure-related
- Research Institution
  Shizuoka University
Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator
- Principal Investigator
  
  TOKUMOTO Toshinobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Shizuoka University
Identification of hormonal active compounds found in coral reef seawater in MauritiusPrincipal Investigator
- Principal Investigator
  
  Tokumoto Toshinobu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Natural medicines
- Research Institution
  Shizuoka University
Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator
- Principal Investigator
  
  TOKUMOTO Toshinobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphology/Structure
- Research Institution
  Shizuoka University
Characterization of steroid membrane receptor in fish oocyte and its role in the induction of oocyte maturationPrincipal Investigator
- Principal Investigator
  
  TOKUMOTO Toshinobu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Shizuoka University
生殖細胞を起源とする奇形腫の多因子モデルマウスの育成と解析
- Principal Investigator
  
  野口基子
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shizuoka University
GENETICS AND DEVELOPMENTAL BIOLOGICAL ANALYSIS OF MECHANISMS INDUCING TESTICULAR TERATOCARCINOGENESIS IN PRIMORDIAL GERM CELLS IN MICE
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY
サイクリン分解の分子機構の解析Principal Investigator
- Principal Investigator
  
  徳元俊伸
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Shizuoka University
マウスの新規な始原生殖細胞増殖因子の単離、同定及び機能解析
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shizuoka University
サイクリン分解の分子機構の解析Principal Investigator
- Principal Investigator
  
  徳元俊伸
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Shizuoka University
プロテアソームによるサイクリンB分解機構の解析Principal Investigator
- Principal Investigator
  
  徳元俊伸
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  動物生理・代謝
- Research Institution
  Shizuoka University
FUNCTION OF THE ter MUTATION AND MOLECULAR CHARACTERISTCS OF A NOVEL PRIMORDIAL GERM CELL GROWTH FACTOR (TERF) IN MICE
- Principal Investigator
  
  NOGUCHI Motoko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C).
- Research Field
  
  Laboratory animal science
- Research Institution
  SHIZUOKA UNIVERSITY

[Book] Advances in Animal Science and Zoology2024
- Author(s)
  Md. Forhad Hossain, Toshinobu Tokumoto
- Total Pages
  21
- Publisher
  NOVA science publishers
- Data Source
  KAKENHI-PROJECT-23K05830
[Book] ナノバイオ・テクノロジー「ステロイドホルモンの新しい作用のしくみ」2016
- Author(s)
  徳元俊伸　他
- Total Pages
  267
- Publisher
  静岡学術出版
- Data Source
  KAKENHI-PROJECT-25440154
[Book] ナノバイオ・テクノロジー「ステロイドホルモンの新しい作用のしくみ」2016
- Author(s)
  徳元俊伸　他
- Total Pages
  267
- Publisher
  静岡学術出版
- Data Source
  KAKENHI-PROJECT-15H05269
[Book] ナノバイオ・テクノロジー2016
- Author(s)
  徳元俊伸
- Total Pages
  267
- Publisher
  静岡学術出版
- Data Source
  KAKENHI-PROJECT-16K07419
[Book] Zebrafish: Topics in Reproduction and Development2014
- Author(s)
  Toshinobu Tokumoto (C.A Lessman and E. Carver ed)
- Total Pages
  300
- Publisher
  NOVA Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-25440154
[Book] Sexual Plasticity and Gametogenesis in Fishes2013
- Author(s)
  Toshinobu Tokumoto (B.Senthilkumaran ed)
- Total Pages
  468
- Publisher
  NOVA Science Publishers Inc.
- Data Source
  KAKENHI-PROJECT-25440154
[Book] New impact on protein modifications in the regulation of reproductive system2007
- Author(s)
  Toshinobu Tokumoto 編
- Total Pages
  167
- Publisher
  Research Signpost
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Book] New impact on protein modifications in the regulation of reproductive system2005
- Author(s)
  Toshinobu Tokumoto編
- Total Pages
  167
- Publisher
  Research Signpost
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Understanding neuroendocrine regulatory pathways of sexual behavior in teleosts2024
- Author(s)
  Ahamed Saokat、Tokumoto Toshinobu
- Journal Title
  
  Aquaculture and Fisheries
  
  Volume: 9 Issue: 3 Pages: 447-454
- DOI
  10.1016/j.aaf.2023.04.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] Establishment of a graphene quantum dot (GQD) based steroid binding assay for the nuclear progesterone receptor (pgr)2024
- Author(s)
  Hossain Md. Forhad、Hossain Shakhawat、Sarwar Jyoti Md. Maisum、Omori Yuki、Ahamed Saokat、Tokumoto Toshinobu
- Journal Title
  
  Biochemistry and Biophysics Reports
  
  Volume: 38 Pages: 101691-101691
- DOI
  10.1016/j.bbrep.2024.101691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] Zebrafish prss59.1 is involved in chorion development2024
- Author(s)
  Rezanujjaman Md.、Pachoensuk Theeranukul、Forhad Hossain Md.、Maisum Sarwar Jyoti Md.、Rubel Rana Md.、Tsutsumi Eisei、Mouri Takumi、Bramastri Susilo Maria、Wanlada Klangnurak、Yamamoto Chihiro、Hasan Ali Md.、Tokumoto Toshinobu
- Journal Title
  
  General and Comparative Endocrinology
  
  Volume: 349 Pages: 114453-114453
- DOI
  10.1016/j.ygcen.2024.114453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] Establishment of a steroid binding assay for goldfish membrane progesterone receptor (mPR) by coupling with graphene quantum dots (GQDs)2024
- Author(s)
  Hossain Forhad、Hossain Shakhawat、Jyoti Maisum Sarwar、Omori Yuki、Tokumoto Toshinobu
- Journal Title
  
  Fish Physiology and Biochemistry
  
  Volume: 50 Issue: 3 Pages: 1-9
- DOI
  10.1007/s10695-024-01315-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] Evidence of binding between diethylstilbestrol (DES) and the goldfish (Carassius auratus) membrane progesterone receptor α2024
- Author(s)
  Hossain Md. Forhad、Mustary Umme Habiba、Tokumoto Toshinobu
- Journal Title
  
  Toxicology Mechanisms and Methods
  
  Volume: 2311185 Issue: 5 Pages: 1-9
- DOI
  10.1080/15376516.2024.2311185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] The Mc4r gene is responsible for the development of experimentally induced testicular teratomas2023
- Author(s)
  Seki Syunsuke、Ohura Kaoru、Miyazaki Takehiro、Naser Abdullah An、Takabayashi Shuji、Tsutsumi Eisei、Tokumoto Toshinobu
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-023-32784-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K05830
[Journal Article] The antagonistic activity of Padina arborescens extracts on mPRα2022
- Author(s)
  Mrityunjoy Acharjee, Md. Hasan Ali, Md. Maisum Sarwar Jyoti, Md. Rezanujjaman, Md. Maksudul Hassan, Md. Rubel Rana, Md. Forhad Hossain, Shinya Kodani and Toshinobu Tokumoto
- Journal Title
  
  Natural Product Research
  
  Volume: 2022 Issue: 11 Pages: 1-5
- DOI
  10.1080/14786419.2022.2120873
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06719, KAKENHI-PROJECT-23K05830
[Journal Article] Establishment of a steroid binding assay for membrane progesterone receptor alpha (PAQR7) by using graphene quantum dots (GQDs)2022
- Author(s)
  Md. Maisum Sarwar Jyoti, Md. Rubel Rana, Md. Hasan Ali and Toshinobu Tokumoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 592 Pages: 1-6
- DOI
  10.1016/j.bbrc.2022.01.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] Purification and identification of the 20S proteasome complex from zebrafish2022
- Author(s)
  Ali Md. Hasan, Md. Maisum Sarwar Jyoti, Md. Rubel Rana Md. Rezanujjaman　and Toshinobu Tokumoto
- Journal Title
  
  Zebrafish
  
  Volume: 19 Issue: 1 Pages: 18-23
- DOI
  10.1089/zeb.2021.0064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] Zebrafish stm is involved in the development of otoliths and of the fertilization envelope2021
- Author(s)
  Theeranukul Pachoensuk, Taketo Fukuyo, Md. Rezanujjaman, Klangnurak Wanlada, Chihiro Yamamoto, Akiteru Maeno, Md. Mostafizur Rahaman, Md. Hasan Ali and Toshinobu Tokumoto
- Journal Title
  
  Reproduction and Fertility
  
  Volume: 2 Issue: 1 Pages: 7-16
- DOI
  10.1530/raf-20-0040
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] Biochemical characterization of zebrafish Prss59.12021
- Author(s)
  Md. Rubel Rana, Md. Forhad Hossain, Md. Hasan Ali, Md. Maisum Sarwar Jyoti and Toshinobu Tokumoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 560 Pages: 32-36
- DOI
  10.1016/j.bbrc.2021.04.118
- NAID
  120007053402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] Pax2a is expressed in oocytes and is responsible for early development and oogenesis in zebrafish2020
- Author(s)
  Theeranukul Pachoensuk, Taketo Fukuyo, Klangnurak Wanlada, Md. Rezanujjaman, Md. Mostafizur Rahaman, Kagura Sasaoka, Md. Maisum Sarwar Jyoti, Md. Rubel Rana, Md. Hasan Ali and Toshinobu Tokumoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 533 Issue: 3 Pages: 592-599
- DOI
  10.1016/j.bbrc.2020.09.059
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] An agonist for membrane progestin receptor (mPR) induces oocyte maturation and ovulation in zebrafish in vivo2020
- Author(s)
  Md. Rezanujjaman, Razain Tanvir, Md. Hasan Ali and Toshinobu Tokumoto
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 592 Issue: 2 Pages: 347-352
- DOI
  10.1016/j.bbrc.2020.05.208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06719
[Journal Article] Candidate gene identification of ovulation- inducing genes by RNA sequencing with an in vivo assay in zebrafish.2018
- Author(s)
  W. Klangnurak, T. Fukuyo, MD. Rezanujjaman, M. Seki, S. Sugano, Y. Suzuki, T. Tokumoto
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 5 Pages: 1-19
- DOI
  10.1371/journal.pone.0196544
- NAID
  120006603025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07419
[Journal Article] Fine selection of up-regulated genes during ovulation by in vivo induction of oocyte maturation and ovulation in zebrafish.2017
- Author(s)
  Wanlada Klangnurak, Toshinobu Tokumoto
- Journal Title
  
  Zoological Letters
  
  Volume: 3
- NAID
  120006603023
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07419
[Journal Article] Detecting membrane progestin receptor (mPR)-interacting compounds from coral seawater in Mauritius.2017
- Author(s)
  T. Tokumoto, S. Kodani, T. Miyazaki, Y. Suzuki, B. Casareto, T. Bahorun, R. Bhagooli
- Journal Title
  
  Western Indian Ocean Journal of Marine Science
  
  Volume: 1 Pages: 77-84
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05269
[Journal Article] <b>Characterization of membrane progestin receptor α (mPRα) of the medaka and role in the induction of oocyte </b><b>maturation </b>2017
- Author(s)
  Shimi Rani Roy, Jun Wang, Mikiko Nakashima, Toshinobu Tokumoto
- Journal Title
  
  Biomed. Res.
  
  Volume: 38 Issue: 1 Pages: 79-87
- DOI
  10.2220/biomedres.38.79
- NAID
  130005242918
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07419
[Journal Article] Establishment of procedures for studying mPR-interacting agents and physiological roles of mPR2016
- Author(s)
  Toshinobu Tokumoto, Md. Babul Hossain, Jun Wang
- Journal Title
  
  Steroids
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05269
[Journal Article] Expression and purification of human membrane progestin receptor α (mPRα)2015
- Author(s)
  Md. Babul Hossain, Takayuki Oshima, Shizuka Hirose, Jun Wang, Toshinobu Tokumoto
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 9 Pages: 1-16
- DOI
  10.1371/journal.pone.0138739
- NAID
  120006603022
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Cell-based assay of nongenomic actions of progestins revealed inhibitory G protein coupling to membrane progestin receptor α (mPRα).2015
- Author(s)
  Mikiko Nakashima, Manami Suzuki, Misako Saida, Yasuhiro Kamei, Md. Babul Hossain, Toshinobu Tokumoto
- Journal Title
  
  Steroids
  
  Volume: 100 Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Cell-based assay of nongenomic actions of progestins revealed inhibitory G protein coupling to membrane progestin receptor α (mPRα)2015
- Author(s)
  Mikiko Nakashima, Manami Suzuki, Misako Saida, Yasuhiro Kamei, Md. Babul Hossain, Toshinobu Tokumoto
- Journal Title
  
  Steroids
  
  Volume: 100 Pages: 21-26
- DOI
  10.1016/j.steroids.2015.04.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Metabolism of bisphenol A by hyper lignin-degrading fungus Phanerochaete sordida YK-624 under non-ligninolytic condition.2014
- Author(s)
  Jianqiao Wang, Yuto Yamada, Akira Notake, Yasushi Todoroki, Toshinobu Tokumoto, Jing Dong, Peter Thomas, Hirofumi Hirai, Hirokazu Kawagishi
- Journal Title
  
  Chemosphere
  
  Volume: 109 Pages: 128-133
- DOI
  10.1016/j.chemosphere.2014.01.029
- NAID
  120005441932
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Purification of the goldfish membrane progestin receptor α (mPRα) expressedin yeast Pichia pastoris2014
- Author(s)
  Takayuki Oshima, Ryo Nakayama, Shimi Rani Roy, Toshinobu Tokumoto
- Journal Title
  
  Biomed. Res.
  
  Volume: 35 Issue: 1 Pages: 47-59
- DOI
  10.2220/biomedres.35.47
- NAID
  130004903859
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Induction of pairing in Xenopus by adding steroids into the water, a novel method for pairing.2013
- Author(s)
  Takehiro Miyazaki, and Toshinobu Tokumoto
- Journal Title
  
  Zoological Science
  
  Volume: 30 Issue: 7 Pages: 565-569
- DOI
  10.2108/zsj.30.565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25440154
[Journal Article] Induction of female-to-male sex reversal in adult zebrafish by fadorozole treatments2013
- Author(s)
  K Takatsu 他７名
- Journal Title
  
  Sci Rep
  
  Volume: 3 Issue: 1 Pages: 3400-3400
- DOI
  10.1038/srep03400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23248034, KAKENHI-PROJECT-24550249, KAKENHI-PROJECT-25440154
[Journal Article] Interactions of diethylstilbestrol (DES) and DES analogues with membrane progestin receptor α (mPRα) and the correlation with their nongenomic progestin activities2007
- Author(s)
  Toshinobu Tokumoto
- Journal Title
  
  Endocrinology (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Interactions of diethylstilbestrol (DES) and DES analogues with membrane progestin receptor a (mPRa) and the correlation with their nongenomic progestin activities.2007
- Author(s)
  T.Tokumoto
- Journal Title
  
  Endocrinology (In press)
- Data Source
  KAKENHI-PROJECT-16650092
[Journal Article] Interactions of diethylstilbestrol (DES) and DES analogues with membrane progestin receptor a (mPRα) and the correlation with their nongenomic progestin activities.2007
- Author(s)
  Toshinobu Tokumoto
- Journal Title
  
  Endocrinology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Interactions of diethylstilbestrol (DES) and DES analogues with membrane progestin receptor α(mPRα) and the correlation with their nongenomic progestin activities2007
- Author(s)
  Toshinobu Tokumoto
- Journal Title
  
  Endocrinology (In press)
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Molecular cloning of cDNA encoding APC11, a catalytic component of anaphase-promoting-complex (APC/C), from goldfish (Carassius auratus) and establishment of in vitro ubiquitinating system.2006
- Author(s)
  M.Tokumoto
- Journal Title
  
  Zool. Sci. 23
  
  Pages: 675-678
- NAID
  110006151749
- Data Source
  KAKENHI-PROJECT-16650092
[Journal Article] Molecular cloning of cDNA encoding APC11, a catalytic component of anaphase-promoting-complex (APC/C), from goldfish (Carassius auratus) and establishment of in vitro ubiquitinating system2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  Zoological Science 23・8
  
  Pages: 675-678
- NAID
  110006151749
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Cloning and identification of a membrane progestin receptor in goldfish ovaries and evidence it is an intermediary in oocyte meiotic maturation.2006
- Author(s)
  M.Tokumoto
- Journal Title
  
  Gen. Comp. Endo. 145
  
  Pages: 101-108
- Data Source
  KAKENHI-PROJECT-16650092
[Journal Article] Molecular Cloning of cDNA Encoding APC 11, a Catalytic Component of Anaphase-promoting-complex (APC/C), from Goldfish (Carassius auratus) and Establishment of in vitro Ubiquitinating System.2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  Zoological Science 23-2
  
  Pages: 675-678
- NAID
  110006151749
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Cloning and identification of a membrane progestin receptor in goldfish ovaries and evidence it is an intermediary in oocyte meiotic maturation.2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  General and Comparative Endocrinology 145-1
  
  Pages: 101-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Cloning and identification of a membrane progestin receptor in goldfish ovaries and evidence it is an intermediary in oocytemeiotic maturation2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  General and Comparative Endocrinology 145・1
  
  Pages: 101-108
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Cloning and identification of a membrane progestin receptor in goldfish ovaries and evidence it is an intermediary in oocyte meiotic maturation.2006
- Author(s)
  M.Tokumoto, et al.
- Journal Title
  
  Gen.Comp.Endocrinol. 145
  
  Pages: 106-108
- Data Source
  KAKENHI-PROJECT-16650092
[Journal Article] Molecular Cloning of cDNA Encoding APC11, a Catalytic Component of Anaphase-promoting-complex (APC/C), from Goldfish (Carassius auratus) and Establishment of in vitro Ubiquitinating System2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  Zoological Science 23・2
  
  Pages: 675-678
- NAID
  110006151749
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Cloning and identification of a membrane progestin receptor in goldfish ovaries and evidence it is an intermediary in oocyte meiotic maturation2006
- Author(s)
  Mika Tokumoto
- Journal Title
  
  General and Comparative Endocrinology 145・1
  
  Pages: 101-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Induction and inhibition of oocyte maturation by EDCs in zebrafish.2005
- Author(s)
  Toshinobu Tokumoto
- Journal Title
  
  Reproductive Biology and Endocrinology 3-69
  
  Pages: 1-9
- NAID
  120000796499
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] The cytoskeleton-dependent localization of cdc2/cyclin B in blastomere cortex during Xenopus embryonic cell cycle.2005
- Author(s)
  T.Tokumoto, et al.
- Journal Title
  
  Mol.Reprod.Dev. 72
  
  Pages: 336-345
- Data Source
  KAKENHI-PROJECT-16650092
[Journal Article] Induction and inhibition of oocyte maturation by EDCs in zebrafish2005
- Author(s)
  Toshinobu Tokumoto
- Journal Title
  
  Reproductive Biology and Endocrinology 3・69
  
  Pages: 1-9
- NAID
  120000796499
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Journal Article] Diethylstilbestrol induces fish oocyte maturation.2004
- Author(s)
  Tokumoto, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 101
  
  Pages: 3686-3690
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Diethylstilbestrol induces fish oocyte maturation.2004
- Author(s)
  Tokumoto, T., et al.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101
  
  Pages: 3686-3690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14380381
[Journal Article] Novel growth factor supporting survival of murine primordial germ cells : Evidence from conditioned medium of ter fetal gonadal somatic cells.2001
- Author(s)
  Takabayashi, S., Sasaoka, Y., Yamashita, M., Tokumoto, T., Ishikawa, K., Noguchi, M.
- Journal Title
  
  Molecular Reproduction and Development 60(3)
  
  Pages: 384-396
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Journal Article] Novel growth factor supporting survival of murine primordial germ cells : Evidence from conditioned medium of ter fetal gonadal somatic cells.2001
- Author(s)
  Takabayashi, S., Sasaoka, Y., Yamashita, M., Tokumoto, T., Ishikawa, K., Noguchi, M.
- Journal Title
  
  Molecular Reproduction and Development 60
  
  Pages: 384-396
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12680809
[Patent] プロゲスチン膜受容体の拮抗薬2023
- Inventor(s)
  徳元俊伸
- Industrial Property Rights Holder
  徳元俊伸
- Industrial Property Rights Type
  特許
- Filing Date
  2023
- Data Source
  KAKENHI-PROJECT-23K05830
[Patent] ステロイドホルモン膜受容体の精製方法2020
- Inventor(s)
  徳元俊伸、大島卓之
- Industrial Property Rights Holder
  徳元俊伸、大島卓之
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Acquisition Date
  2020
- Data Source
  KAKENHI-PROJECT-20K06719
[Patent] ステロイドホルモン膜受容体の精製方法2013
- Inventor(s)
  徳元俊伸、大島卓之
- Industrial Property Rights Holder
  静岡大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-136980
- Filing Date
  2013-06-28
- Data Source
  KAKENHI-PROJECT-25440154
[Patent] 内分泌撹乱性物質のスクリーニング方法2005
- Inventor(s)
  徳元俊伸
- Industrial Property Rights Holder
  静岡大学
- Industrial Property Number
  2005-267894
- Filing Date
  2005-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17570175
[Presentation] Phenotypic analysis of gene knock-out strains of highly upregulated genes during ovulation in zebrafish2023
- Author(s)
  Toshinobu Tokumoto
- Organizer
  International Symposium on Reproductive Physiology of Fish 12th ISRPF at Crete, Olympia, Greece
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K05830
[Presentation] ゼブラフィッシュにおけるStmは卵膜上のノブ型構造及び卵膜孔の形成に関与する2022
- Author(s)
  毛利匠, Theeranukul Pachoensuk, Md. Rezanujjaman, Klangnurak Wanlada, 山本千尋 and 徳元俊伸
- Organizer
  日本動物学会第93回早稲田大会
- Data Source
  KAKENHI-PROJECT-20K06719
[Presentation] Expression and purification of human membrane estrogen receptor (hmER) and establishment of high throughput assays using GQDs2022
- Author(s)
  HOSSAIN Md. Forhad, RANA Md. Rubel, JYOTI Md. Maisum Sarwar, OMORI Yuki, HOSSAIN Md. Babul, TOKUMOTO Toshinobu
- Organizer
  第46回日本比較内分泌学会大会及びシンポジウム
- Data Source
  KAKENHI-PROJECT-20K06719
[Presentation] ゼブラフィッシュにおける排卵関連遺伝子prss59.1の機能解析2022
- Author(s)
  堤瑛誠, Md. Rezanujjaman, Theeranukul Pachoensuk, Md. Forhad Hossain, Md.Rubel Rana, 毛利匠, Maria Bramastri Susilo, Klangnurak Wanlada, 山本千尋, Md. Hasan Ali, 徳元俊伸
- Organizer
  日本動物学会第93回早稲田大会
- Data Source
  KAKENHI-PROJECT-20K06719
[Presentation] Role of Starmarker (stm) Gene for Fertilization in Zebrafish2019
- Author(s)
  Taketo Fukuyo, Wanlada Klangnurak, Md.Rezanujjaman, Toshinobu Tokumoto
- Organizer
  2019 9th International Conference on Bioscience, Biochemistry and Bioinformatics (ICBBB2019) at Singapore
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Establishment of Gene Knock-out Strain of pax2a Selected as an Ovulation-inducing Gene by in vivo Assay by Genome Editing in Zebrafish2019
- Author(s)
  Theeranukul Pachoensuk, Fukuyo Taketo, Klangnurak Wanlada, Toshinobu Tokumoto
- Organizer
  2019 9th International Conference on Bioscience, Biochemistry and Bioinformatics (ICBBB2019) at Singapore
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] IDENTIFICATION OF OVULATION-INDUCING GENES SELECTED BY IN VIVO ASSAY BY GENOME EDITING IN ZEBRAFISH2018
- Author(s)
  Theeranukul, P., Fukuyo, T., Klangnurak, W., Tokumoto, T.
- Organizer
  日本動物学会第89回大会
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Coral reefs stay on new frontiers of natural compounds.2018
- Author(s)
  T. Tokumoto
- Organizer
  State and conservation of our coral reefs
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05269
[Presentation] ゼブラフィッシュのstarmaker(stm)遺伝子のゲノム編集による機能解析2018
- Author(s)
  ワンラダクラングヌラック、福與健人、エムディレザヌッジャマン、徳元俊伸
- Organizer
  日本動物学会第89回大会
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] プロゲスチン膜受容体 (mPR) 遺伝子群変異メダカ系統の表現型解析2018
- Author(s)
  王軍、Abdullah AN Naser 、徳元俊伸
- Organizer
  第４３回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] キンギョ脳におけるプロゲスチン膜受容体 (mPR) の局在2017
- Author(s)
  王　軍、原口省吾、徳元俊伸
- Organizer
  第４２回日本比較内分泌学会大会
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] ゼブラフィシュ生体内卵成熟・排卵誘導法による排卵誘導候補遺伝子の特異的選択2017
- Author(s)
  ワンラダクラングヌラック、福與健人、エムディレザヌッジャマン、今村聖実、堀内映実、菅野純夫、鈴木穣、徳元俊伸
- Organizer
  日本動物学会第88回大会
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] An application of in vivo assay to identify ovulation-inducing genes in zebrafish2016
- Author(s)
  Klangnurak W, Tosaka M, Imumura K, Horiuchi T, Sugano S, Suzuki Y, Tokumoto T.
- Organizer
  The joint meeting of the 22nd International Congress of Zoology and the 87th Meeting of the Zoological Society of Japan
- Place of Presentation
  沖縄コンベンションセンター　沖縄県　那覇市
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] キンギョ脳におけるプロゲスチン膜受容体 (mPR) の発現とステロイドとの結合親和性2016
- Author(s)
  王　軍、原口省吾、徳元俊伸
- Organizer
  第４１回日本比較内分泌学会大会
- Place of Presentation
  北里大学海洋生命科学部　神奈川県　相模原市
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Identification of membrane progestin receptor (mPR) interacting compounds from coral seawater in Mauritius2016
- Author(s)
  S. Kodani, T. Miyazaki, R. Bhagooli, T. Bahorun and T. Tokumoto
- Organizer
  The University Research Week 2016
- Place of Presentation
  University of Mauritius, Mauritius
- Year and Date
  2016-09-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05269
[Presentation] Approaches for detailed analysis of membrane progestin receptor (mPR) protein and for physiological roles of mPR2016
- Author(s)
  T. Tokumoto
- Organizer
  8th International Symposium of Fish Endocrinology
- Place of Presentation
  Lindholmen Conference Centre Gothenburg Sweden
- Year and Date
  2016-06-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Identification of ovulation-inducing genes selected by the method for in vivo induction of oocyte maturation and ovulation in zebrafish.2016
- Author(s)
  Klangnurak W, Tosaka M, Imumura K, Horiuchi T, Sugano S, Suzuki Y, Tokumoto
- Organizer
  The Japanese Medaka and Zebrafish Meeting (JMZM)
- Place of Presentation
  基礎生物学研究所　愛知県　岡崎市
- Year and Date
  2016-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Establishment of membrane progestin receptor (mPR) mutant Medaka strains to analyse central roles of mPRs2016
- Author(s)
  J. Wang, S.R. Roy, I. Hara, K.Naruse, Y. Kamei, Y. Taniguchi, T. Tokumoto
- Organizer
  The joint meeting of the 22nd International Congress of Zoology and the 87th Meeting of the Zoological Society of Japan
- Place of Presentation
  沖縄コンベンションセンター　沖縄県　那覇市
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07419
[Presentation] Membrane progestin receptor (mPR) a possible target for new drugs2015
- Author(s)
  Toshinobu Tokumoto, MD Babul Hossain, Jun Wang, Takehiro Miyazaki
- Organizer
  9th SFRR-Africa
- Place of Presentation
  Hennessy Park Hotel, (Mauritius)
- Year and Date
  2015-07-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05269
[Presentation] ESTABLISHMENT OF PROCEDURES FOR mPR INTERACTING AGENTS AND STUDY ON PHYSIOLOGICAL ROLES OF mPR2015
- Author(s)
  Toshinobu Tokumoto
- Organizer
  9th Rapid Responses to Steroid Hormones
- Place of Presentation
  Taipei TAIWAN
- Year and Date
  2015-06-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05269
[Presentation] Membrane progestin receptor (mPR) a possible target for new drugs2015
- Author(s)
  Toshinobu Tokumoto, MD Babul Hossain, Jun Wang, Takehiro Miyazaki
- Organizer
  9th SFRR-Africa 27-29
- Place of Presentation
  Hennessy Park Hotel, (Mauritius)
- Year and Date
  2015-07-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440154
[Presentation] ESTABLISHMENT OF PROCEDURES FOR mPR INTERACTING AGENTS AND STUDY ON PHYSIOLOGICAL ROLES OF mPR2015
- Author(s)
  Toshinobu Tokumoto
- Organizer
  9th Rapid Responses to Steroid Hormones
- Place of Presentation
  Taipei TAIWAN
- Year and Date
  2015-06-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440154
[Presentation] In vivo induction of oocyte maturation and ovulation in zebrafish; an ideal model to distinguish between genomic and nongenomic actions of steroids2014
- Author(s)
  Toshinobu Tokumoto
- Organizer
  Workshop in Ramkhamhaeng University
- Place of Presentation
  Ramkhamhaeng University, Thailand
- Year and Date
  2014-10-27
- Data Source
  KAKENHI-PROJECT-25440154
[Presentation] Towards elucidation of the roles of membrane progestin receptors (mPRs) in the non-genomic steroidal actions.2013
- Author(s)
  Toshinobu Tokumoto
- Organizer
  Rapid Responses to Steroid Hormones 8th International Meeting
- Place of Presentation
  Eri, PA, USA
- Data Source
  KAKENHI-PROJECT-25440154
[Presentation] Establishment of the mutant strains of membrane progestin receptors (mPRs) in the Medaka fish and investigate their central roles
- Author(s)
  himi Rani Roy, Takayuki Oshima, Kaori Miyaoku, Etsuko Sugita, Kanae Takatsu, Miki Ogusu, Babul Hossain, Jun Wang, Ikuyo Hara, Kiyoshi Naruse, Yasuhiro Kamei, Yoshihito Taniguchi, Toshinobu Tokumoto
- Organizer
  日本比較内分泌学会
- Place of Presentation
  岡崎コンファレンスセンター, Japan
- Year and Date
  2014-11-07 – 2014-11-14
- Data Source
  KAKENHI-PROJECT-25440154

1. NOGUCHI Motoko (40021951)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
2. NOZAKI Masami (30189394)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KIMURA Tohru (50280962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小谷真也 (20510621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 鈴木款 (30252159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. CASARETO Beatriz (60402244)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Theeshan Bahorun

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Ranjeet Bagooli

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. BEATORISU Kasareto

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tokumoto Toshinobu 徳元 俊伸

TOKUMOTO Toshinobu 徳元 俊伸

Research Projects

Research Products

Co-Researchers

Functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator

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Review Section

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Functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator

Principal Investigator

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Research Institution

Identification of hormonal active compounds found in coral reef seawater in MauritiusPrincipal Investigator

Principal Investigator

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Studies on functions of membrane steroid receptors and molecular mechanism of oocyte maturation and ovulationPrincipal Investigator

Principal Investigator

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Research Institution

Characterization of steroid membrane receptor in fish oocyte and its role in the induction of oocyte maturationPrincipal Investigator

Principal Investigator

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生殖細胞を起源とする奇形腫の多因子モデルマウスの育成と解析

Principal Investigator

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Research Institution

GENETIC AND DEVELOPMENTAL ANALYSIS OF MECHANISMS UNDERLYING TERATOCARCINOGENESIS IN THE MOUSE GERM CELLS.

Principal Investigator

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GENETICS AND DEVELOPMENTAL BIOLOGICAL ANALYSIS OF MECHANISMS INDUCING TESTICULAR TERATOCARCINOGENESIS IN PRIMORDIAL GERM CELLS IN MICE

Principal Investigator

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サイクリン分解の分子機構の解析Principal Investigator

Principal Investigator

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マウスの新規な始原生殖細胞増殖因子の単離、同定及び機能解析

Principal Investigator

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サイクリン分解の分子機構の解析Principal Investigator

Principal Investigator

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Research Institution

プロテアソームによるサイクリンB分解機構の解析Principal Investigator

Principal Investigator

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Research Institution

Tokumoto Toshinobu 徳元俊伸

TOKUMOTO Toshinobu 徳元俊伸

[Book] ナノバイオ・テクノロジー「ステロイドホルモンの新しい作用のしくみ」2016

[Book] ナノバイオ・テクノロジー「ステロイドホルモンの新しい作用のしくみ」2016