WADA Shun-ichi 和田俊一

… Alternative Names

和田俊一ワダシュンイチ

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Researcher Number	30278593
Other IDs
Affiliation (Current)	2025: 大阪医科薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 大阪医科薬科大学, 薬学部, 准教授 2021 – 2023: 大阪医科薬科大学, 薬学部, 准教授 2018: 大阪薬科大学, 薬学部, 准教授 2016 – 2017: 大阪薬科大学, 薬学部, 准教授(移行) 2010 – 2015: 大阪薬科大学, 薬学部, 准教授 … More 2006 – 2007: 大阪薬科大学, 薬学部, 講師 2003: 大阪薬科大学, 助手 2002: 大阪薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Drug development chemistry / Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Physical pharmacy Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator Aib / α-aminoisobutyric acid / 核酸医薬 / 膜透過性ペプチド / DNA / RGD配列 / siRNA / 両親媒性ヘリックスペプチド / アンチセンス / オリゴヌクレオチド … More / ペプチドベクター / α,α-ジ置換アミノ酸 / Endosomolysis / 細胞膜透過性透過性ペプチド / 両親媒性へリックスペプチド / 膜透過性ヘペプチド / peptaibol / oligonucleotide / Peptide-derived vector / ペプタイボール / インテグリンレセプター / RNA干渉 / 核酸医薬品 / ヘリックス / ベクター / ペプチド / 遺伝子治療 / アンチセンスオリゴヌクレオチド … More Except Principal Investigator Ac-225 / 225Ac / 核医学治療 / がん幹細胞 / CD44 / ペプチド / アルファ線核種 Less

生体内環境応答型エンドソーム脱出機能を有するAib含有ペプチドの合成と機能評価Principal Investigator
- Principal Investigator
  
  和田俊一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Osaka Medical and Pharmaceutical University
Development of radionuclide therapy with a fusion of CSC binding peptides and high energy alpha nuclides
- Principal Investigator
  
  Mitsuyoshi Yoshimoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  National Cancer Center Japan
Development of Aib-containing delivery tool of siRNA into cancer cells with ability of spatio-temporal control of siRNA actionsPrincipal Investigator
- Principal Investigator
  
  Wada Shun-ichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences
Design of Cyclic RGD-Conjugated Aib-Containing Amphipathic Helical Peptides for Targeted Delivery of Small Interfering RNAPrincipal Investigator
- Principal Investigator
  
  Shun-ichi Wada
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences
Development of membrane-permeable Aib-containing peptide for delivery of oligonucleotide drugsPrincipal Investigator
- Principal Investigator
  
  WADA Shun-ichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences
Development of peptide vectors containing Aid residues for gene therapyPrincipal Investigator
- Principal Investigator
  
  WADA Shun-ichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Osaka University of Pharmaceutical Sciences
遺伝子治療を目指した膜透過・チャンネル形成ペプチドのベクターとしての可能性Principal Investigator
- Principal Investigator
  
  和田俊一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Osaka University of Pharmaceutical Sciences

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2008 2007 Other

All Journal Article Presentation Book

[Book] 医療・診断をささえるペプチド科学　－再生医療・DDS・診断への応用－2017
- Author(s)
  平野義明（監修），和田俊一（分担）
- Total Pages
  315
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Syntheses of prodrug-type 2'-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2'-hydroxy oligonucleotides under reducing condition2018
- Author(s)
  Hayashi Junsuke、Ochi Yosuke、Morita Yasuyuki、Soubou Katsuma、Ohtomo Yuhei、Nishigaki Misa、Tochiyama Yuko、Nakagawa Osamu、Wada Shun-ichi、Urata Hidehito
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 22 Pages: 5838-5844
- DOI
  10.1016/j.bmc.2018.10.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K21234, KAKENHI-PROJECT-16K08331
[Journal Article] Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA2018
- Author(s)
  Hayashi Junsuke、Nishigaki Misa、Ochi Yosuke、Wada Shun-ichi、Wada Fumito、Nakagawa Osamu、Obika Satoshi、Harada-Shiba Mariko、Urata Hidehito
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 28 Issue: 12 Pages: 2171-2174
- DOI
  10.1016/j.bmcl.2018.05.016
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Synthesis and biological evaluation of histone deacetylase and DNA topoisomerase II-Targeted inhibitors2018
- Author(s)
  Yamashita Mitsuaki、Tahara Teruyuki、Hayakawa Shinya、Matsumoto Hironobu、Wada Shun-ichi、Tomioka Kiyoshi、Iida Akira
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 8 Pages: 1920-1928
- DOI
  10.1016/j.bmc.2018.02.042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Structure-activity relationship study of Aib-containing amphipathic helical peptide-cyclic RGD conjugates as carriers for siRNA delivery2017
- Author(s)
  S. Wada, A. Takesada, Y. Nagamura, E. Sogabe, R. Ohki, J. Hayashi, H. Urata
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Pages: 5378-5381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Design, synthesis, and evaluation of DNA topoisomerase II-targeted nucleosides2017
- Author(s)
  H. Matsumoto, M. Yamashita, T. Tahara, S. Hayakawa, S. Wada, K. Tomioka, A. Iida
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 25 Pages: 4133-4144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Syntheses of Prodrug-Type Phosphotriester Oligonucleotides Responsive to Intracellular Reducing Environment for Improvement of Cell Membrane Permeability and Nuclease Resistance2017
- Author(s)
  J. Hayashi, Y. Samezawa, Y. Ochi, S. Wada, H. Urata
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 27 Pages: 3135-3138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Design of Cyclic RGD-Conjugated Aib-Containing Amphipathic Helical Peptides for Targeted Delivery of Small Interfering RNA2016
- Author(s)
  Wada S, Iwata M, Ozaki Y, Ozaki T, Hayashi J, Urata H.
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 24 Pages: 4478-4485
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] 核酸医薬のデリバリーを指向した機能性核酸・ペプチド関連分子の創製2016
- Author(s)
  浦田秀仁，和田俊一
- Journal Title
  
  化学工業
  
  Volume: 67 Pages: 48-60
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K08331
[Journal Article] Design of Multivalent Cyclic RGD-Conjugated MAP(Aib) for Targeted Delivery of Small Interfering RNA2015
- Author(s)
  Shun-ichi Wada, Masashi Iwata, Junsuke Hayashi, Hidehito Urata
- Journal Title
  
  Peptide Science
  
  Volume: 52 Pages: 255-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460161
[Journal Article] Aib-Containing Peptide Analogs: Cellular Uptake and Utilization in Oligonucleotide Delivery2014
- Author(s)
  Shun-ichi Wada, Tomoe Urase,Yuka Hasegawa, Kenta Ban, Aya Sudani, Yui Kawai, Junsuke Hayashi and Hidehito Urata
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 22 Pages: 6776-6780
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460161
[Journal Article] Cyclic RGD-MAP(Aib) conjugate for delivery of small interfering RNA2014
- Author(s)
  Shun-ichi Wada, Yuka Ozaki, Takashi Ozaki, Masashi Iwata, Junsuke Hayashi, and Hidehito Urata
- Journal Title
  
  Peptide Science
  
  Volume: 51 Pages: 157-158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460161
[Journal Article] Designed Aib-containing amphipathic helix peptide for oligonucleotide delivery into cells2013
- Author(s)
  Shun-ichi Wada, Yuki Hashimoto, Hirokazu Tsuda, Osamu Nakagawa, and Hidehito Urata
- Journal Title
  
  Peptide Science
  
  Volume: 49 Pages: 235-236
- NAID
  10031161614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460161
[Journal Article] Effect of Ala Replacement with Aib in Amphipathic Cell-Penetrating Peptide on Oligonucleotide Delivery into Cells2013
- Author(s)
  Shun-ichi Wada, Yuki Hashimoto, Yui Kawai, Kaori Miyata, Hirokazu Tsuda, Osamu Nakagawa, and Hidehito Urata
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 21 Issue: 24 Pages: 7669-7673
- DOI
  10.1016/j.bmc.2013.10.029
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460161
[Journal Article] Cellular Uptake of Covalent Conjugates of Oligonucleotide with Membrane-modifying Peptide, Peptaibol2012
- Author(s)
  Shun-ichi Wada, Yasunari Hitora, Saori Yokoe, Osamu Nakagawa, and Hidehito Urata
- Journal Title
  
  Bioorg. & Med. Chem
  
  Volume: 20 Pages: 3219-3222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590109
[Journal Article] Designed Aib-containing amphipathic helix peptide for oligonucleotide delivery into cells2012
- Author(s)
  Shun-ichi Wada
- Journal Title
  
  Peptide Science
  
  Volume: 2012 Pages: 235-236
- NAID
  10031161614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590109
[Journal Article] Cellular uptake of covalent conjugates of oligonucleotide with membrane-modifying peptide, peptaibol2012
- Author(s)
  Shun-ichi Wada
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 20 Pages: 3219-3222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590109
[Journal Article] Cellular uptake of Aib-containing amphipathic helix peptide2011
- Author(s)
  和田俊一, 津田浩和, 岡田てる美, 浦田秀仁
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: VOL.21 Issue: 19 Pages: 5688-5691
- DOI
  10.1016/j.bmcl.2011.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590109
[Journal Article] Cellular Uptake of Aib-containing Amphi- pathic Helix Peptide2011
- Author(s)
  Shun-ichi Wada, Hirokazu Tsuda, Terumi Okada, and Hidehito Urata
- Journal Title
  
  Bioorg. & Med. Chem. Lett
  
  Volume: 21 Pages: 5688-5691
- URL
  http://dx.doi.org/10.1016/j.bmcl.2011.08.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590109
[Journal Article] Translocation of an Aib-containing Peptide through Cell Membranes2008
- Author(s)
  Shun-ichi Wada, Yasunari Hitora, Reiko Tanaka, Hidehito Urata
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Journal Article] Translocation of an Aib-containing Peptide through Cell Membranes2008
- Author(s)
  和田俊一
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590111
[Journal Article] Functionalized 20-Residual Peptaibol for Nucleic Acid Delivery2007
- Author(s)
  Shun-ichi Wada(和田俊一)
- Journal Title
  
  Chemistry ＆ Biodiversity 4・5
  
  Pages: 991-997
- Data Source
  KAKENHI-PROJECT-18590111
[Journal Article] Functionalized 20-Residual Peptaibol for Nucleic Acid Delivery2007
- Author(s)
  和田俊一
- Journal Title
  
  Chemistry & Biodiversity 4
  
  Pages: 991-997
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590111
[Journal Article] Functionalized 20-Residual Peptaibol for Nucleic Acid Delivery2007
- Author(s)
  Shun-ichi Wada and Reiko Tanaka
- Journal Title
  
  Chemistry & Biodiversity 4(5)
  
  Pages: 991-997
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] 還元環境に応答するプロドラッグ型 RNA の配列拡張を指向した合成研究2019
- Author(s)
  越智洋輔, 林淳祐, 森田康之, 西垣美沙, 和田俊一, 浦田秀仁
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] ペプチド性キャリアMAP(Aib)-cRGD によるmicroRNA-145 の細胞内導入2019
- Author(s)
  和田俊一, 谷口高平, 林淳祐, 内山和久, 浦田秀仁
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 細胞内還元環境に応答する直鎖ジスルフィド修飾を施したプロドラッグ型リン酸トリエステル(PTE) 核酸の合成2019
- Author(s)
  林淳祐, 船木涼平, 越智洋輔, 和田俊一, 浦田秀仁
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 細胞内還元環境により活性化するプロドラッグ型2'-O-methyldithiomethyl-siRNA の効率的RNAi効果~ 非プロドラッグ型2’-O-methyl siRNAのRNAi活性との比較~2018
- Author(s)
  林淳祐，西垣美沙，越智洋輔，和田俊一，和田郁人，小比賀聡，斯波真理子，浦田秀仁
- Organizer
  日本核酸医薬学会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] ペプチド性siRNAキャリアMAP(Aib)-cRGDのヘリックス軸の長さ及びN-末端置換基の影響2018
- Author(s)
  和田俊一，武貞安納，曽我部絵里，大木理恵子，河北亜希，林淳祐，浦田秀仁
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] Consecutive formation of thymine-HgII -thymine base pairs catalyzed by DNA polymerases2018
- Author(s)
  H. Urata, T. Funai, C. Tagawa, A. Ono, S. Wada
- Organizer
  The 45th International Symposium on Nucleic Acids Chemistry 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 細胞内還元環境により天然型核酸へと変換されるプロドラッグ型PTE 核酸の開発~直鎖ジスルフィド修飾による還元環境応答性の評価~2018
- Author(s)
  船木涼平，林淳祐，越智洋輔，和田俊一，浦田秀仁
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 配列拡張を指向した 2'-O-メチルジチオメチル-オリゴヌクレオチドの合成2018
- Author(s)
  越智洋輔，森田康之，林淳祐，和田俊一，浦田秀仁
- Organizer
  第68回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] General synthesis and knockdown activity of prodrug-type 2'-O-methyldithiomethyl2018
- Author(s)
  Y. Ochi, J. Hayashi, Y. Morita, M. Nishigaki, S. Wada, H. Urata
- Organizer
  The 45th International Symposium on Nucleic Acids Chemistry 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] Delivery of siRNA and microRNA into Cells by Aib-containing Amphipathic Helical Peptides2018
- Author(s)
  S. Wada, K. Taniguchi, H. Hamazaki, A. Yamada, J. Hayashi, K. Uchiyama, H. Urata
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 機能性siRNAキャリアとしてのMAP(Aib)-cRGD複合体の構造活性相関研究2017
- Author(s)
  和田俊一，武貞安納，長村友里恵，林淳祐，浦田秀仁
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] Arbuzov様反応を利用したリン酸トリエステル核酸の簡便な合成法の開発2017
- Author(s)
  橋崎大輔，林淳祐，和田俊一，浦田秀仁
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] cRGD 配列を有するAib 含有ペプチドのsiRNA デリバリー効果2017
- Author(s)
  曽我部絵里，大木理恵子，今田真以子，林淳祐，和田俊一，浦田秀仁
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 細胞内還元環境で活性化するプロドラッグ型siRNA の2'修飾基がRNAi 活性に与える影響2017
- Author(s)
  西垣美沙，越智洋輔，林淳祐，和田俊一，浦田秀仁
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] DNA polymerase による金属錯体型塩基対の形成に対する pyrimidine 5 位修飾の影響2017
- Author(s)
  吉村沙奈子，林淳祐，和田俊一，浦田秀仁
- Organizer
  第67回日本薬学会近畿支部総会・大会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] Structure-activity relationship study of MAP(Aib)-cRGD conjugates as carriers for siRNA delivery2017
- Author(s)
  和田俊一，武貞安納，曽我部絵里，大木理恵子，河北亜希，林淳祐，浦田秀仁
- Organizer
  第54回　日本ペプチドシンポジウム
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] 細胞内還元環境で活性化するプロドラッグ型siRNA（REDUCT-siRNA）のRNA干渉効果に及ぼす2’-O-修飾基の影響2017
- Author(s)
  林淳祐，西垣美沙，越智洋輔，和田俊一，和田郁人，小比賀聡，斯波真理子，浦田秀仁
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] MAP(Aib)-cRGD conjugates as carriers for delivery of small interfering RNA2016
- Author(s)
  和田俊一，武貞安納，長村友里恵，林淳祐，浦田秀仁
- Organizer
  第53回日本ペプチドシンポジウム
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16K08331
[Presentation] Design of multivalent cyclic RGD-conjugated MAP(Aib) for targeted delivery of small interfering RNA2015
- Author(s)
  和田俊一、岩田征士、林淳祐、浦田秀仁
- Organizer
  第52回日本ペプチドシンポジウム
- Place of Presentation
  平塚市　中央公民館（神奈川県・平塚市）
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] MAP(Aib)-オリゴヌクレオチド複合体の合成及び細胞膜透過性研究2014
- Author(s)
  宮田佳緒里、林淳祐、中川治、和田俊一、浦田秀仁
- Organizer
  第64 回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都府・京都市）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Aib含有ペプチドTV-XIIaとその類縁体の細胞膜透過性研究（２）2014
- Author(s)
  和田俊一，壽谷彩，浦瀬友絵，長谷川由佳，伴健太，中川治，浦田秀仁
- Organizer
  日本薬学会第13４年会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] 細胞認識機能を兼ね備えた膜透過性 Aib 含有ヘリックスペプチドの合成と核酸医薬への応用(2)2014
- Author(s)
  尾崎友香、尾崎嵩、岩田征士、林淳祐、中川治、和田俊一、浦田秀仁
- Organizer
  第64 回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都府・京都市）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Aib 含有ペプチド類縁体の細胞膜透過性研究（３）2014
- Author(s)
  河合悠衣、壽谷彩、浦瀬友絵、長谷川由佳、林淳祐、中川治、和田俊一、浦田秀仁
- Organizer
  第64 回日本薬学会近畿支部総会・大会
- Place of Presentation
  京都薬科大学（京都府・京都市）
- Year and Date
  2014-10-11
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Aib 含有ペプチド-オリゴヌクレオチドコンジュゲート体の合成と機能評価2013
- Author(s)
  壽谷彩，橋本佑樹，尾崎友香，浦瀬友絵，長谷川由佳，中川治，和田俊一，浦田秀仁
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学・田辺キャンパス（京都）
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Aib含有両親媒性へリックスペプチドを用いたオリゴヌクレオチドの細胞内移送2013
- Author(s)
  和田俊一
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Translocation of Aib-containing peptide analogs through cell membranes2013
- Author(s)
  和田俊一，河合悠衣，長谷川由佳，浦瀬友絵，中川治，浦田秀仁
- Organizer
  第4回アジア-太平洋国際ペプチドシンポジウム（第50回日本ペプチドシンポジウム）
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] 細胞認識機能を兼ね備えた膜透過性Aib含有ヘリックスペプチドの合成と核酸医薬への応用2013
- Author(s)
  尾崎嵩，橋本佑樹, 中川治，和田俊一，浦田秀仁
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学・田辺キャンパス（京都）
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] 膜透過性ペプチド(MAP)のAib置換による核酸分子の細胞内移行性の影響2013
- Author(s)
  橋本佑樹，河合悠衣，宮田佳緒里，中川治，和田俊一，浦田秀仁
- Organizer
  第63回日本薬学会近畿支部大会
- Place of Presentation
  同志社女子大学・田辺キャンパス（京都）
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Aib 含有両親媒性へリックスペプチドを用いたオリゴヌクレオチドの細胞内移送2013
- Author(s)
  橋本佑樹,津田浩和,中川治,和田俊一,浦田秀仁
- Organizer
  日本薬学会第133年会
- Place of Presentation
  横浜
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Designed Aib-containing amphipathic helix peptide for oligonucleotide delivery into cells2012
- Author(s)
  和田俊一,橋本侑樹,津田浩和,中川治, 浦田秀仁
- Organizer
  第49回ペプチド討論会
- Place of Presentation
  鹿児島
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] TV-XIIa-オリゴヌクレオチド複合体のアンチセンス効果の検討2012
- Author(s)
  和田俊一,横江沙緒里,人羅康匠,中川治,浦田秀仁
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] TV-XIIa-オリゴヌクレオチド複合体のアンチセンス効果の検討2012
- Author(s)
  和田俊一, 横江沙緒里, 人羅康匠, 中川治, 浦田秀仁
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Conjugates of antisense oligonucleotides with Aib-containing peptide : effects on cellular uptake and antisense effect2011
- Author(s)
  和田俊一, 人羅康匠, 横江沙緒里, 浦田秀仁
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター(札幌)
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Aib 含有両親媒性ヘリックスペプチドを用いたオリゴヌクレオチドの細胞膜透過性検討2011
- Author(s)
  津田浩和,岡田てる美,和田俊一,浦田秀仁
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Aib 含有両親媒性ヘリックスペプチドの細胞膜透過性2011
- Author(s)
  津田浩和,岡田てる美,和田俊一,浦田秀仁
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Aib含有両親媒性ヘリックスペプチドの細胞膜透過性2011
- Author(s)
  津田浩和, 岡田てる美, 和田俊一, 浦田秀仁
- Organizer
  日本薬学会代131年会
- Place of Presentation
  ツインメッセ静岡(静岡県)
- Year and Date
  2011-03-31
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Aib含有両親媒性ヘリックスペプチドを用いたオリゴヌクレオチドの細胞膜透過性検討2011
- Author(s)
  津田浩和, 岡田てる美, 和田俊一, 浦田秀仁
- Organizer
  第61回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学ポートアイランドキャンパス(兵庫)
- Year and Date
  2011-11-22
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Conjugates of antisense oligonucleotides with2011
- Author(s)
  和田俊一,人羅康匠,横江沙緒里,浦田秀仁
- Organizer
  Aib-containing peptide: effects on cellular uptake and antisense effect
- Place of Presentation
  札幌
- Year and Date
  2011-09-28
- Data Source
  KAKENHI-PROJECT-22590109
[Presentation] Aib含有ペプチドTV-XIIaとその類縁体の細胞膜透過性研究2008
- Author(s)
  和田俊一
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Aib含有ペプチドTV-XIIaとその類縁体の細胞膜透過性研究2008
- Author(s)
  和田俊一
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜(神奈川県横浜市)
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Wada Membrane permeability of Aib-containing peptide, TV-XIIa and its derivative2008
- Author(s)
  Shun-ichi
- Organizer
  The 128th Annual Meeting of the Pharmaceutical Society of Japn
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2008-03-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Aib含有ペプチドの膜透過性に関する研究2007
- Author(s)
  和田俊一
- Organizer
  第57回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪薬科大学(大阪府高槻市)
- Year and Date
  2007-10-27
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Wada Delivery of oligonucleotides into cells by Aib-containing peptides2007
- Author(s)
  Shun-ichi
- Organizer
  The 127th Annual Meeting of the Pharmaceutical Society of Japn
- Place of Presentation
  Toyama, Japan
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Aib含有ペプチドを用いたオリゴヌクレオチドの細胞内導入2007
- Author(s)
  和田俊一
- Organizer
  日本薬学会第127年会
- Place of Presentation
  富山
- Year and Date
  2007-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Aib含有ペプチドの膜透過性に関する研究2007
- Author(s)
  和田俊一
- Organizer
  第57回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] Wada Membrane permeability of Aib-containing peptides2007
- Author(s)
  Shun-ichi
- Organizer
  The 57th Annual Meeting of the Pharmaceutical Society of Japn Kinki-branch
- Place of Presentation
  Osaka, Japan
- Year and Date
  2007-10-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590111
[Presentation] 細胞認識機能を兼ね備えたCyclic RGD-MAP(Aib)コンジュゲート体の合成とsiRNAのデリバリーの可能性
- Author(s)
  和田俊一、岩田征士、尾崎友香、尾崎嵩、林淳祐、浦田秀仁
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学、兵庫医療大学、神戸サンボーホール、デザイン・クリエイティブセンター神戸（兵庫県・神戸市）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25460161
[Presentation] Cyclic RGD-MAP (Aib) conjugates for delivery of small interfering RNA
- Author(s)
  和田俊一、尾崎友香、尾崎嵩、岩田征士、林淳祐、浦田秀仁
- Organizer
  第51回日本ペプチドシンポジウム
- Place of Presentation
  徳島大学大塚講堂（徳島県・徳島市）
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PROJECT-25460161

1. URATA Hidehito (80211085)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
2. Mitsuyoshi Yoshimoto (00345638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 越智洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WADA Shun-ichi 和田 俊一

和田 俊一 ワダ シュンイチ

Research Projects

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生体内環境応答型エンドソーム脱出機能を有するAib含有ペプチドの合成と機能評価Principal Investigator

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Development of radionuclide therapy with a fusion of CSC binding peptides and high energy alpha nuclides

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Development of Aib-containing delivery tool of siRNA into cancer cells with ability of spatio-temporal control of siRNA actionsPrincipal Investigator

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Design of Cyclic RGD-Conjugated Aib-Containing Amphipathic Helical Peptides for Targeted Delivery of Small Interfering RNAPrincipal Investigator

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Development of membrane-permeable Aib-containing peptide for delivery of oligonucleotide drugsPrincipal Investigator

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Development of peptide vectors containing Aid residues for gene therapyPrincipal Investigator

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遺伝子治療を目指した膜透過・チャンネル形成ペプチドのベクターとしての可能性Principal Investigator

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[Book] 医療・診断をささえるペプチド科学 －再生医療・DDS・診断への応用－2017

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[Journal Article] Syntheses of prodrug-type 2'-O-methyldithiomethyl oligonucleotides modified at natural four nucleoside residues and their conversions into natural 2'-hydroxy oligonucleotides under reducing condition2018

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[Journal Article] Effective gene silencing activity of prodrug-type 2'-O-methyldithiomethyl siRNA compared with non-prodrug-type 2'-O-methyl siRNA2018

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[Journal Article] Synthesis and biological evaluation of histone deacetylase and DNA topoisomerase II-Targeted inhibitors2018

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[Journal Article] Structure-activity relationship study of Aib-containing amphipathic helical peptide-cyclic RGD conjugates as carriers for siRNA delivery2017

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[Journal Article] Design, synthesis, and evaluation of DNA topoisomerase II-targeted nucleosides2017

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[Journal Article] Syntheses of Prodrug-Type Phosphotriester Oligonucleotides Responsive to Intracellular Reducing Environment for Improvement of Cell Membrane Permeability and Nuclease Resistance2017

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[Journal Article] Design of Cyclic RGD-Conjugated Aib-Containing Amphipathic Helical Peptides for Targeted Delivery of Small Interfering RNA2016

WADA Shun-ichi 和田俊一

和田俊一ワダシュンイチ

[Book] 医療・診断をささえるペプチド科学　－再生医療・DDS・診断への応用－2017