TAKATA Akiko 高田晶子

… Alternative Names

TOMOKUNI Akiko 友国晶子

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Researcher Number	30278957
External Links
Affiliation (based on the past Project Information) *help	2005: 川崎医大, 医学部, 助手 1996 – 2004: 川崎医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hygiene / Hygiene Except Principal Investigator Hygiene / Hygiene / 内科学一般
Keywords	Principal Investigator 珪酸塩化合物 / caspase-3 / アポトーシス / 自己免疫 / apoptosis / epitope mapping / 抗Fas自己抗体 / 珪肺症 / PBMC / じん肺症 … More / chrysotile B / 石綿肺症 / Annexin-V / ProteinChip analysis / Annexin V / Fas … More Except Principal Investigator 珪肺症 / Fas / IL-10 / silicosis / Fas ligand / 自己免疫 / 自己抗体 / 珪酸化合物 / FOXP3 / 制御性T細胞 / STATIN / ATRA / 遺伝子発現 / preventive medicine / autoimmune response / Work-related diseases / HLA型 / apoptosis / HLA class II / アポトーシス / 自己免疫疾患 / 作業関連物質 / suppressive effect / CD4+CD25-T cell / CD4+CD25+ regulatory T cell / autoimmune disease / autoantibody / immunological disorder / 末梢血単核細胞 / 細胞増殖抑制能 / CD4^+CD25^-T細胞 / CD4^+CD25^+制御性T細胞 / 自己反応性T細胞 / 抗核抗体 / 免疫異常 / T CELL RECEPTOR / APOPTOSIS / CELLINE / REGULATORY T CELL / T CELL / SILICA / ASBESTOS / MAPキナーゼ / ミトコンドリア経路 / 活性酸素種 / T細胞受容体 / 培養株 / T細胞 / 珪酸 / アスベスト / PROTEIN EXPRESSION / ANTI-HER2-ANTIBODY / MAP-KINASE / GENE EXPRESSION / CELL CULTURE / MYELOMA / ビスフォスフォート剤 / サリドマイド / 蛋白発現 / 抗HER2抗体 / MAP-kinaseシグナル伝達 / 細胞培養 / 骨髄腫 / HLA typing / silicate / silicossis / 有害物質感受性 / 予防医学 / 珪酸塩化合物 / 作業関連疾患 / HLA-typing / silica silicate / 珪酸症 / alternative splicing / caspase / silica compound / Fas ligahd / 選択的splicing / Caspase / Apoptosis / T lymphocytes / Sillicate / Silica / Autoimmunity / リンパ球 / プロテインチップ Less

珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator
- Principal Investigator
  
  高田晶子
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
FALURE OF SELF TOLERANCE INDUCED BY ENVIRONMELAL SUBSTANCES : AUTOIMMUNE DYSREGULATION FOUND IN SILICOSIS PATIENIS AS A MODEL
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Phenotypic and functional alteration of regulatory T cells in the peripheral blood of patients with silicosis
- Principal Investigator
  
  HYODOH Fuminori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator
- Principal Investigator
  
  高田晶子
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
EXTRACTION OF FACTORS RELATED TO THE ONCOGENESIS, PROGRESSION AND SENSITIVITY TO THE THERAPEUTIC AGENTS IN HUMAN MYELOMA CELLS AS IN VITRO MODEL
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
プロテインチップを用いた珪肺症患者における免疫学的病態の解析
- Principal Investigator
  
  植木絢子
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator
- Principal Investigator
  
  友国晶子
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Risk factors analysis using HLA typing for preventive medicine of worker's immunological sensitivities against silica dust.
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Analysis of HLA disease association among the patients patients with silicosis-To make a check list to prevent work-related diseases.
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School
Occupational exposure of toxic materials and development of autoimmune diseases
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  KAWASAKI MEDICAL SCHOOL
Research for immunodysregulation and acquisition of autoimmunity induced by silica compounds
- Principal Investigator
  
  OTSUKI Takemi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  KAWASAKI MEDICAL SCHOOL
作業関連物質による自己免疫疾患発症機序の解析
- Principal Investigator
  
  UEKI Ayako
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hygiene
- Research Institution
  Kawasaki Medical School

All 2006 2005 2004 Other

All Journal Article

[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis. 〔Review article〕2006
- Author(s)
  Otsuki T, Miura Y, Nishimura Y, Hyodoh F, Takata A, Kusaka M, Katsuyama H, Tomita M, Ueki A, Kishimoto T
- Journal Title
  
  Exp Biol Med (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping and Function of anti-Fas autoantibody in patients with silicosis2005
- Author(s)
  Takata-Tomokuni, A.
- Journal Title
  
  Immunol. 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590491
[Journal Article] Detection, epitope-mapping and function of anti-Fas autoantibody in patients with silicosis2005
- Author(s)
  Takata-Tomokuni, A
- Journal Title
  
  Immunol. 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590491
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子
- Journal Title
  
  日本衛生学雑誌 60(1)
  
  Pages: 30-37
- Data Source
  KAKENHI-PROJECT-16590491
[Journal Article] 珪肺症例T細胞における膜Fas発現2005
- Author(s)
  大槻剛巳, 高田晶子, 植木絢子, 三浦由恵, 西村泰光, 草加勝康, 勝山博信
- Journal Title
  
  臨床環境医学 14
  
  Pages: 119-127
- NAID
  10020417134
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子
- Journal Title
  
  日本衛生学雑誌 60・1
  
  Pages: 30-37
- Data Source
  KAKENHI-PROJECT-16790331
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Ixozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki H, Kusaka M, Arikuni H, Otsuki T
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子, 三浦由恵, 兵藤文則, 勝山博信, 植木絢子, 大槻剛巳
- Journal Title
  
  日本衛生学雑誌 60
  
  Pages: 30-37
- NAID
  10014312270
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例に検出されるFasとその関連分子の異常2005
- Author(s)
  高田晶子, 三浦由恵, 兵藤文則, 勝山博信, 植木絢子, 大槻剛巳
- Journal Title
  
  日本衛生学雑誌 60(1)
  
  Pages: 30-37
- NAID
  10014312270
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human polyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T
- Journal Title
  
  Scand J Immunol 61
  
  Pages: 442-448
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Isozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki H, Kusaka M, Arikuni H, Otsuki T
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyaaa H, Otsuki T
- Journal Title
  
  Immunol Lett 98
  
  Pages: 145-152
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human palyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T.
- Journal Title
  
  Scand J Immunal 61
  
  Pages: 442-448
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T
- Journal Title
  
  Immunol Lett 98
  
  Pages: 145-152
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Detection, epitope-mapping, and function of anti-Fas autoantibody in patients with silicosis.2005
- Author(s)
  Takata-Tomokuni A, Ueki A, Shiwa M, Isozaki Y, Hatayama T, Katsuyama H, Hyodoh F, Fujimoto W, Ueki I, Kusaka M, Arikuni H, Otsuki T.
- Journal Title
  
  Immunology 116
  
  Pages: 21-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A.2005
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T.
- Journal Title
  
  Immunol Lett 98(1)
  
  Pages: 145-152
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Inhibitory effects of anti-oxidants on apoptosis of a human polyclonal T cell line, MT-2, induced by an asbestos, chrysotile-A.2005
- Author(s)
  Hyodoh F, Takata-Tomokuni A, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Katsuyama H, Matsuo Y, Otsuki T
- Journal Title
  
  Scand J Immunol 61
  
  Pages: 442-448
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例で認められた抗Fas自己抗体の機能解析2004
- Author(s)
  高田-友国晶子, 植木絢子, 三浦由恵, 草加勝康, 勝山博信, 大槻剛巳
- Journal Title
  
  臨床環境医学 13(2)(印刷中)
- NAID
  10029423582
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例で認められた抗Fas自己抗体の機能解析2004
- Author(s)
  高田-友国晶子
- Journal Title
  
  臨床環境医学 13・2(印刷中)
- Data Source
  KAKENHI-PROJECT-16790331
[Journal Article] Regulatory T cells in silicosis patients2004
- Author(s)
  Hyodoh, F., Takata, A., Otsuki, T.
- Journal Title
  
  Jpn.J.Hyg. 59(1)
  
  Pages: 158-158
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590491
[Journal Article] Asbestosによるリンパ球細胞死の検討2004
- Author(s)
  大槻剛巳, 三浦由恵, 高田晶子, 兵藤文則
- Journal Title
  
  ImunoTox Let 9
  
  Pages: 7-9
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Secretory Ig A in saliva and academic stress.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatayama T, Takata A, Hyodoh F, Tsujita S, Ueki A, Morimoto K
- Journal Title
  
  Int J Immunopathol Pharmaco 17
  
  Pages: 45-48
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Secretory Ig A in saliva and academic stress.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatayama T, Takata A, Hyodoh F, Tsujita S, Ueki A, Morimoto K.
- Journal Title
  
  Int J Immunopathol Pharmacol 17(2S)
  
  Pages: 45-48
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] 珪肺症症例で認められた抗がFas自己抗体の機能解析2004
- Author(s)
  高田-友国晶子, 植木絢子, 三浦由恵, 草加勝康, 勝山博信, 大槻剛巳
- Journal Title
  
  臨床環境医学 13
  
  Pages: 102-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Effects of genetic and nutritional factors on bone mineral density in young adults.2004
- Author(s)
  Otsuki T, Sakaguchi H, Hatta E, Hatayama T, Hatada S, Miura Y, Takata-Tomokuni A, Hyodoh F, Tomomitsu T, Fukunaga M, Katsuyama H.
- Journal Title
  
  Int J Mol Med 14(4)
  
  Pages: 669-676
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Expression of PGP9.5 (Protein Gene Product 9.5)/UCHL-1 (Ubiquitin-C-terminal hydrolase 1) in human myeloma cells.2004
- Author(s)
  Otsuki T, Yata K, Takata-Tomokuni A, Hyodoh F, Miura Y, Sakaguchi H, Hatayama T, Hatada S, Tsujioka T, Sato Y, Murakami H, Sadahira Y, Sugihara T.
- Journal Title
  
  Br J Haematol 127
  
  Pages: 292-298
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Induction of CD69 antigen expression in peripheral blood mononuclear cells on exposure to silica, but not by asbestos/chrysotile-A.
- Author(s)
  Wu P, Hyodoh F, Hatayama T, Sakaguchi H, Hatada S, Miura Y, Takata-Tomokuni A, Katsuyama H, Otsuki T
- Journal Title
  
  Immunol Lett (In press)
- Data Source
  KAKENHI-PROJECT-16390175
[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis.
- Author(s)
  Otsuki T, Miura Y, Nishimura Y, Hyodoh F, Takata A, Kusaka M, Katsuyama H, Tomita M, Ueki, A, Kashimoto T
- Journal Title
  
  Exp Biol Med(in press) (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390175

1. OTSUKI Takemi (40160551)

# of Collaborated Projects: 8 results

# of Collaborated Products: 23 results
2. HYDOH Fuminori (80069070)

# of Collaborated Projects: 6 results

# of Collaborated Products: 20 results
3. UEKI Ayako (10069031)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. KAWAKAMI Yasuhiko (10234030)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. NISHIMURA Yasumitsu (90360271)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. MIURA Yoshie (00388935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
7. TAKESHITA Tatsuya (20150310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUREBAYASHI Junichi (10248255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TAKATA Akiko 高田 晶子

TOMOKUNI Akiko 友国 晶子

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Co-Researchers

珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator

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珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator

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珪酸塩化合物により惹起されるヒト免疫異常の解析Principal Investigator

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[Journal Article] Alterations of Fas and Fas-related molecules in patients with silicosis. 〔Review article〕2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Detection, epitope-mapping and Function of anti-Fas autoantibody in patients with silicosis2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] Detection, epitope-mapping and function of anti-Fas autoantibody in patients with silicosis2005

Author(s)

TAKATA Akiko 高田晶子

TOMOKUNI Akiko 友国晶子