NARITA Miwako 成田美和子

Researcher Number	30281009
External Links
Affiliation (based on the past Project Information) *help	2016 – 2020: 新潟大学, 医歯学系, 教授 2011 – 2015: 新潟大学, 医歯学系, 准教授 2003 – 2004: 新潟大学, 医学部, 助教授 2001: Faculty OF Medicine, Niigata University, Assistant, 医学部, 助手
Review Section/Research Field	Principal Investigator Clinical oncology / Tumor therapeutics / Basic Section 52010:General internal medicine-related Except Principal Investigator Hematology / Hematology / Laboratory medicine
Keywords	Principal Investigator WT1 / sgRNA / apoptosis / 腫瘍細胞 / 白血病 / mRNA / tRNaseZL / アポトーシス / Bcl-2 / small guide RNA … More / TRUE gene silencing / tRNase Z / NB4 / ヘプタマーsgRNA / 腫瘍 / HL-60 / CTL / IMiDs / NK / antigen specific CTL / MLPC / 腫瘍抗原 / 測定法 … More Except Principal Investigator dendritic precursor cells / myelodendritic leukemia / leukemia derived dendritic cells / CTL line / anti-leukemic immunotherapy / CTL / SEREX / myelodendric leukemia / dendritic cells / mupelodendritic leukemia / anti-leukemic immune-Therapy / 樹状細胞 / 急性白血病 / 白血病性樹状細胞 / CDla / CD83 / 混合白血球培養 / 抗原呈示能 / 白血病関連抗原 / 細胞傷害活性 / Leukemia / 白血病特異抗原 / HLA / leukemia associated antigens / 腫瘍免疫療法 / MLPC法 / WT1特異的細胞傷害性T細胞 / 腫瘍免疫 / MLPC / 細胞傷害性T細胞 / 免疫チェックポイント阻害薬 / WT1 / 骨髄系悪性腫瘍 Less

腫瘍抗原特異的細胞障害性T細胞のクローン性増幅と機能解析法の開発Principal Investigator
- Principal Investigator
  
  成田美和子
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Niigata University
Establishment of evaluation method of tumor immunity for application of immune checkpoint inhibitor to AML/MDS
- Principal Investigator
  
  Shibasaki Yasuhiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Niigata University
Development of novel anti-tumor therapy target mRNA cleavage using a new methodPrincipal Investigator
- Principal Investigator
  
  Miwako Narita
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Niigata University
Development of mRNA ablation using completely new functional nucleic acid constructsPrincipal Investigator
- Principal Investigator
  
  NARITA Miwako
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Niigata University
Identification of novel leukemia associated antigen which may useful for immunotherapy of leukemia patients
- Principal Investigator
  
  FURUKAWA Tatsuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Niigata University
Study on pathophysiology and treatment of dendritic precursor cell derived myelodendritic cell leukemia
- Principal Investigator
  
  TAKAHASHI Masuhiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  NIIGATA UNIVERSITY

All 2019 2018 2017 2014 2013 2012

All Journal Article Presentation Patent

[Journal Article] Heterogeneity of intrahepatic iron deposition in transfusion-dependent iron overload patients with hematological malignancies2018
- Author(s)
  Kobayashi Hironori、Yoshimura Norihiko、Uemura Shun、Katagiri Takayuki、Tanaka Tomoyuki、Ushiki Takashi、Fuse Kyoko、Shibasaki Yasuhiko、Narita Miwako、Sone Hirohito、Masuko Masayoshi
- Journal Title
  
  Leukemia Research
  
  Volume: 70 Pages: 41-44
- DOI
  10.1016/j.leukres.2018.05.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09006
[Journal Article] Refinement of the Glasgow Prognostic Score as a pre-transplant risk assessment for allogeneic hematopoietic cell transplantation2018
- Author(s)
  Shibasaki Yasuhiko、Suwabe Tatsuya、Katagiri Takayuki、Tanaka Tomoyuki、Ushiki Takashi、Fuse Kyoko、Sato Naoko、Yano Toshio、Kuroha Takashi、Hashimoto Shigeo、Narita Miwako、Furukawa Tatsuo、Sone Hirohito、Masuko Masayoshi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 108 Pages: 282-289
- DOI
  10.1007/s12185-018-2463-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09006
[Journal Article] Peripheral T-cell lymphoma, not otherwise specified: a retrospective single-center analysis2017
- Author(s)
  鈴木隆晴、柴崎康彦、森山雅人、増子正義、成田美和子、曽根博仁、青木定夫、中村直哉、大島孝一、瀧澤淳、河本啓介、田村秀、上村駿、海發茜、根本洋樹、小林弘典、牛木隆志、布施香子
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 58 Issue: 8 Pages: 905-911
- DOI
  10.11406/rinketsu.58.905
- NAID
  130006067957
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09006, KAKENHI-PROJECT-15K19547
[Journal Article] The Glasgow Prognostic Score as a pre-transplant risk assessment for allogeneic hematopoietic cell transplantation.2017
- Author(s)
  Shibasaki Yasuhiko、Suwabe Tatsuya、Katagiri Takayuki、Tanaka Tomoyuki、Kobayashi Hironori、Fuse Kyoko、Ushiki Takashi、Sato Naoko、Yano Toshio、Kuroha Takashi、Hashimoto Shigeo、Narita Miwako、Furukawa Tatsuo、Sone Hirohito、Masuko Masayoshi
- Journal Title
  
  Clin Transplant.
  
  Volume: 31
- DOI
  10.1111/ctr.13103
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-17K09006, KAKENHI-PROJECT-16H03260, KAKENHI-PROJECT-15K19547
[Journal Article] Successful umbilical cord blood hematopoietic stem cell transplantation in a patient with adult T-cell leukemia/lymphoma initially achieving complete remission with anti-CC chemokine receptor 4 antibody combined chemotherapy2017
- Author(s)
  Suwabe T, Shibasaki Y, Kaihatsu A, Katagiri T, Miyakoshi S, Fuse K, Kobayashi H, Ushiki T, Moriyama M, Takizawa J, Narita M, Sone H, Masuko M.
- Journal Title
  
  Jpn. J. Clin. Hematol.
  
  Volume: 58(1) Issue: 1 Pages: 32-36
- DOI
  10.11406/rinketsu.58.32
- NAID
  130005394599
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09868, KAKENHI-PROJECT-15K19547, KAKENHI-PROJECT-17K09006
[Journal Article] Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies.2014
- Author(s)
  Takahashi M, Elbarbary RA, Watanabe N, Goto A, Kamiya D, Watabe Y, Uchiyama T, Narita M, Takahashi M, Takahashi Y, Ishihara N, Miyazawa T, Yoshida T, Kawano M, Tamura M, Nashimoto M.
- Journal Title
  
  Leuk Research
  
  Volume: 38 Pages: 808-815
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26430157
[Journal Article] Induction of apoptosis of leukemic cells by TRUE gene silencing using small guide RNAs targeting the WT1 mRNA.2013
- Author(s)
  Watanabe N, Narita M, Yamahira A, Taniguchi T, Furukawa T, Yoshida T, Miyazawa T, Nashimoto M, Takahashi M.
- Journal Title
  
  Leuk Res.
  
  Volume: 37 Pages: 580-5
- DOI
  10.4081/rt.2011.e24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501304
[Journal Article] A naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells2013
- Author(s)
  Takahashi M, Elbarbary RA, Nakashima A, Abe M, Watanabe N, Narita M, Takahashi M, Tamura M, Yoshida T, Nashimoto M.
- Journal Title
  
  Cancer Lett.
  
  Volume: 328 Pages: 362-8
- DOI
  10.1155/2010/623593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23501304
[Journal Article] naked RNA heptamer targeting the human Bcl-2 mRNA induces apoptosis of HL60 leukemia cells2013
- Author(s)
  Takahashi M, Elbarbary RA, Nakashima A, Abe M, Watanabe N, Narita M, Takahashi M, Tamura M, Yoshida T, Nashimoto M
- Journal Title
  
  Cancer Letters
  
  Volume: 328(2) Pages: 362-368
- Data Source
  KAKENHI-PROJECT-23501304
[Journal Article] Induction of apoptosis of leukemic cells by TRUE gene silencing using small guide RNAs targeting the WT1 mRNA2013
- Author(s)
  Watanabe N, Narita M, Saito A, Yamahira A, Taniguchi T, Furukawa T, Yoshida T, Miyazawa T, Nashimoto M, Takahashi M
- Journal Title
  
  Leuk Res
  
  Volume: 37(5) Pages: 580-585
- Data Source
  KAKENHI-PROJECT-23501304
[Patent] United States Patent2014
- Inventor(s)
  M Nashimoto, M Narita,他
- Industrial Property Rights Holder
  M Nashimoto, M Narita,他
- Industrial Property Rights Type
  特許
- Filing Date
  2014
- Acquisition Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-26430157
[Patent] ヒト白血病細胞のアポトーシスを誘導するヘプタマー型スモールガイド核酸2012
- Inventor(s)
  梨本正之、高橋益廣、成田美和子、吉田哲郎、宮澤達也
- Industrial Property Rights Holder
  学校法人新潟科学技術学園新潟薬科大学、国立大学法人新潟大学
- Industrial Property Rights Type
  特許
- Acquisition Date
  2012-08-24
- Overseas
- Data Source
  KAKENHI-PROJECT-23501304
[Presentation] Monitoring of Persistent CTLs over 10 Years Using MLPC after WT1 Peptide Vaccine in a CML Patient.2019
- Author(s)
  Suwabe T, Ogawa S, Goto W, Sato H, Fuse K, Shibasaki Y, Sone H, Masuko M, Narita M.
- Organizer
  The 10th JSH International Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09006
[Presentation] MLPC法はMDS患者の末梢血および骨髄血に存在するWT1特異的CD8陽性T細胞の検出に有用である2019
- Author(s)
  諏訪部達也、柴崎康彦、佐藤廣幸、田村秀、片桐隆幸、布施香子、曽根博仁、成田美和子、増子正義.
- Organizer
  日本血液学会総会
- Data Source
  KAKENHI-PROJECT-17K09006
[Presentation] Monitoring of Persistent CTLs over 10 Years Using MLPC after WT1 Peptide Vaccine in a CML Patient.2019
- Author(s)
  Tatsuya Suwabe, Sara Ogawa, Wakana Goto, Hiroyuki Sato, Kyoko Fuse, Yasuhiko Ahibasaki, Hirohito Sone, Masayoshi Masuko, Miwako Narita
- Organizer
  The 10th JSH International Symposium 2019
- Data Source
  KAKENHI-PROJECT-18K07410
[Presentation] WT1 specific CTL expansion using antigen presenting cell line and IMid.2018
- Author(s)
  Sara Ogawa, Suwabe Tatsuya, Yashuhiko Shibasaki, Wakana Goto, Masayoshi Masuko, Takayoshi Uchiyama, Shigeo Hashimoto, Jun Takizawa, Hirohito Sone, Masuhiro Takahashi, Miwako Narita
- Organizer
  第47回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K07410
[Presentation] Further Prognostic Factors for Stratification of Patients in the High-Risk HCT-CI Group Undergoing Allogeneic HCT2017
- Author(s)
  Yasuhiko Shibasaki, Tatsuya Suwabe, Takayuki Katagiri, Tomoyuki Tanaka, Hironori Kobayashi, Kyoko Fuse, Takashi Ushiki, Miwako Narita, Hirohito Sone, Masayoshi Masuko
- Organizer
  第59回アメリカ血液学会 (59th ASH Annual Meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09006

1. NASHIMOTO Masayuki (30228069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. FURUKAWA Tatsuo (00272849)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. TAKAHASHI Masuhiro (90179531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. FUSE Ichiro (90242429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Shibasaki Yasuhiko (50568540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. 小池正 (30170161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 増子正義 (70397115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. 牛木隆志

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
9. 曽根博仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田中司朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NARITA Miwako 成田 美和子

Research Projects

Research Products

Co-Researchers

腫瘍抗原特異的細胞障害性T細胞のクローン性増幅と機能解析法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of evaluation method of tumor immunity for application of immune checkpoint inhibitor to AML/MDS

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel anti-tumor therapy target mRNA cleavage using a new methodPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of mRNA ablation using completely new functional nucleic acid constructsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel leukemia associated antigen which may useful for immunotherapy of leukemia patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on pathophysiology and treatment of dendritic precursor cell derived myelodendritic cell leukemia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Heterogeneity of intrahepatic iron deposition in transfusion-dependent iron overload patients with hematological malignancies2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Refinement of the Glasgow Prognostic Score as a pre-transplant risk assessment for allogeneic hematopoietic cell transplantation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peripheral T-cell lymphoma, not otherwise specified: a retrospective single-center analysis2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] The Glasgow Prognostic Score as a pre-transplant risk assessment for allogeneic hematopoietic cell transplantation.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful umbilical cord blood hematopoietic stem cell transplantation in a patient with adult T-cell leukemia/lymphoma initially achieving complete remission with anti-CC chemokine receptor 4 antibody combined chemotherapy2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies.2014

Author(s)

Journal Title

Data Source

[Journal Article] Induction of apoptosis of leukemic cells by TRUE gene silencing using small guide RNAs targeting the WT1 mRNA.2013

Author(s)

Journal Title

DOI

Data Source

NARITA Miwako 成田美和子