HARAYAMA HIROSHI 原山洋

… Alternative Names

HARAYAMA Hiroshi 原山洋

Less

Researcher Number	30281140
Other IDs
External Links
Affiliation (Current)	2025: 神戸大学, 農学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2025: 神戸大学, 農学研究科, 教授 2015: 神戸大学, 大学院農学研究科, 教授 2012 – 2015: 神戸大学, (連合)農学研究科(研究院), 教授 2012: 神戸大学, 大学院・農学研究科, 教授 2011: 神戸大学, (連合)農学研究科(研究院), 准教授 … More 2007 – 2011: Kobe University, Graduate School of Agricultural Science, Associate Professor 2010: Kobe University, 大学院・農学研究科, 准教授 2005 – 2006: Kobe University, Graduate School of Science and Technology, Associate Professor, 自然科学研究科, 助教授 2004: 神戸大学, 大学院・自然科学研究科, 助教授 1999 – 2001: KOBE UNIVERSITY, GRADUATESCHOOL OF SCIENCE AND TECHNOLOGY, ASSOCIATE PROFESSOR, 大学院・自然科学研究科, 助教授 1998: 神戸大学, 大学院自然科学研究科, 助手 1997 – 1998: 神戸大学, 大学院・自然科学研究科, 助手 1996: 神戸大学, 自然科学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Applied animal science / Applied animal science / Basic Section 42010:Animal production science-related / Animal production science / Medium-sized Section 42:Veterinary medical science, animal science, and related fields Except Principal Investigator Applied animal science / Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Basic Section 42040:Laboratory animal science-related / Animal production science / Clinical veterinary science
Keywords	Principal Investigator 精子 / ウシ / 人工授精 / 応用動物 / 雄性繁殖能力 / 畜産学 / ブタ / cAMP / ハイパーアクチベーション / 環状アデノシン1リン酸 … More / 細胞内シグナリング / 精巣上体 / 鞭毛運動 / 雄性繁殖学 / hyperactivation / intracellular signaling / sperm / カルシウム / 細胞凝集 / 精子成熟 / シアロタンパク質 / 応用動物学 / 分子性状検査法 / capacitation / motility / cattle / 受精能獲得 / 運動 / pig / phospholipase / protein kinase / fertilization / リン酸化 / SYK / チロシンキナーゼ / タンパク質キナーゼC / カルシウムストアー / イノシトール3リン酸 / ホスホリパーゼ / タンパク質キナーゼ / 受精 / 膜安定化因子 / リン酸化タンパク質 / 精子凍結保存 / 凍結保存 / カルパイン / グルコース / アクロソーム / チロシンリン酸化タンパク質 / 先体反応 / 鞭毛超活性化運動 / 黒毛和種 / カルモジュリン / カルシウムチャンネル / アルブミン / タンパク質 / 免疫組織化学 / 糖鎖 … More Except Principal Investigator 精子 / ブタ / cAMP / 夏季不妊症 / 先体反応 / INSL3 / 受精能獲得 / 冷蔵保存 / コレステロール / 体外受精 / 人工授精 / ハイパーアクチベーション / 受精 / 胚 / 卵子 / ウシ / 受容体 / 生殖細胞 / 生殖器 / 蛍光免疫測定法 / 卵胞嚢腫 / 黄体 / 雌ウシ / INSL3受容体（RXFP2） / 卵胞 / 超音波画像検査 / 成長 / 黒毛和種雌ウシ / サンドイッチ時間分解蛍光免疫測定 / 発生工学 / 生殖生物学 / 実験動物学 / 融合 / boar / acrosome reaction / cholesterol / summer infertility / spermatozoa / ジアシルグリセロール / 豚 / Bicarbonate / Cell Agglutination / Protein / Epididymis / Capacitation / Sperm / Pig / 間接蛍光抗体法 / クロロテトラサイクリン / 炭酸水素イオン / 細胞凝集 / タンパク質 / 精巣上体 / embryo production / in vitro fertilization / in vitro culture / oocyte maturation / oocyte growth / folliculogenesis / oogenesis / pig / 体外成熟卵母細胞 / 体外発育卵母細胞 / 胚生産 / 体外培養 / 卵母細胞の成熟 / 卵母細胞の発育 / 卵胞形成 / 卵子形成 / グタ / gene expression / postimplantation development / in vitro early development / parthenogenesis / 遺伝子発現 / 体内発生限界 / 体外初期発生 / 単為発生 / チロシンリン酸化 / カルシウム / Ca / 再生医療 / 重炭酸 / 単為発生2倍体 / 着床前発生能力 / 応用動物科学 / クローディン / 胚盤胞形成 / 活性化2倍体 / グルコース代謝 / claudins / タイトジャンクション / 着床前発生 / イオノホア / 臨床 / シクロオキシゲナーゼ / 希釈液 / 夏季不妊 / 産科精子 / 臨床繁殖 Less

ウシの人工授精成績の向上を目的とした先体反応発生能力を指標とする精子検査法の開発Principal Investigator
- Principal Investigator
  
  原山洋
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kobe University
Elucidation of roles and signal transduction of INSL3 in bovine gamate maturaiton, fertilization and embryo development
- Principal Investigator
  
  川手憲俊
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattlePrincipal Investigator
- Principal Investigator
  
  原山洋
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  Kobe University
Studies on expressions and roles of INSL3 secretory dynamics and its receptor expression in reproductive organs and germ cells in female cattle
- Principal Investigator
  
  川手憲俊
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Osaka Metropolitan University
  Osaka Prefecture University
Elucidation of the mechanisms of sperm-egg fusion using genetically modified mice
- Principal Investigator
  
  Noda Taichi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Kumamoto University
  Osaka University
Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull spermPrincipal Investigator
- Principal Investigator
  
  HARAYAMA HIROSHI
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Kobe University
Studies on the mechanisms that cholesterol exerts its therapeutic effects on boar spermatozoa affected with summer infertility
- Principal Investigator
  
  Murase Tetsuma
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Gifu University
Characterization and utilization of SPACA1 proteins for the purpose of establishment of a new method to predict freezability of bull sperm before cryopreservationPrincipal Investigator
- Principal Investigator
  
  HARAYAMA HIROSHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Kobe University
Etiology of boar spermatozoa affected with summer infertility in an attempt to develop a novel therapy
- Principal Investigator
  
  Murase Tetsuma
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Gifu University
Expression of claudin family proteins in preimplantation embryos in the pig
- Principal Investigator
  
  MIYAKE MASASHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Animal production science
- Research Institution
  Kobe University
Development of methods to evaluate molecular characteristics of livestock spermatozoa by the detection of aberrant fertility-regulating factorsPrincipal Investigator
- Principal Investigator
  
  HARAYAMA HIROSHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Animal production science
- Research Institution
  Kobe University
Enhancement of the tolerance to the storage in boar and mouse spermatozoa by the re-maturation in vitroPrincipal Investigator
- Principal Investigator
  
  HARAYAMA Hiroshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
Development of clinical therapeutic methods against failure of fertilizing functions causing summer infertility in boars
- Principal Investigator
  
  MURASE Tetsuma
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical veterinary science
- Research Institution
  Gifu University
Targeted therapy for defect of fertilizing ability in the spermatozoa from subfertile livestockPrincipal Investigator
- Principal Investigator
  
  HARAYAMA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
An invention of method to predict reproductive performance of Japanese Black cattle by the evaluation of sperm ability to exhibit flagellar hyperactivationPrincipal Investigator
- Principal Investigator
  
  HARAYAMA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
An invention of method to suppress expression of sperm fertilizing ability for the purpose of establishment of production system of porcine embryosPrincipal Investigator
- Principal Investigator
  
  HARAYAMA Hiroshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
ブタ精子のキャパシテーション過程での頭部間凝集に及ぼすカルシウムの影響Principal Investigator
- Principal Investigator
  
  原山洋
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
Changes and functions of Anti-Agglutinin in boar spermatozoa during their capacitation
- Principal Investigator
  
  KATO Seishiro
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
Anti-Agglutinin出現機序の生化学的および免疫組織学的解析Principal Investigator
- Principal Investigator
  
  原山洋
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
ブタ活性化卵子の初期発生能ならびに単為発生胚の初期胚特異タンパク質の発現性
- Principal Investigator
  
  MIYAKE Masashi
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University
Studies on production of pig embryos from growing oocytes
- Principal Investigator
  
  KATO Seishiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  KOBE UNIVERSITY
精巣上体液中の精子頭部間凝集抑制タンパク質を修飾する糖鎖の特性解析Principal Investigator
- Principal Investigator
  
  原山洋
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Applied animal science
- Research Institution
  Kobe University

[Book] 繁殖生物学改訂版（第2版）（第5章3 受精 pp. 228～237）2020
- Author(s)
  原山洋，内藤邦彦
- Total Pages
  351
- Publisher
  インターズー
- ISBN
- Data Source
  KAKENHI-PROJECT-19K22366
[Book] 発生生物学（5.3 哺乳類の受精 pp. 44～47）2019
- Author(s)
  原山洋
- Total Pages
  169
- Publisher
  株式会社培風館
- ISBN
- Data Source
  KAKENHI-PROJECT-19K22366
[Book] 発生生物学基礎から応用への展開 (第5章3節)2019
- Author(s)
  原山　洋
- Total Pages
  208
- Publisher
  培風館
- ISBN
  9784563078232
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Comparative characteristics between calyculin A-induced and thimerosal-induced hyperactivation of cryopreserved bovine spermatozoa2023
- Author(s)
  MIYAMOTO Natsuko、OHYA Akihiro、DURITAHALA、SAKASE Mitsuhiro、HARAYAMA Hiroshi
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 69 Issue: 3 Pages: 170-177
- DOI
  10.1262/jrd.2023-007
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05951, KAKENHI-PROJECT-22H04922
[Journal Article] Calmodulin is involved in the occurrence of extracellular Ca2+-dependent full-type hyperactivation in boar ejaculated spermatozoa incubated with cyclic AMP analogs2021
- Author(s)
  Wada Atsushi、Harayama Hiroshi
- Journal Title
  
  Animal Science Journal
  
  Volume: 92 Issue: 1
- DOI
  10.1111/asj.13552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22366
[Journal Article] Characteristics of bull sperm acrosome associated 1 proteins2020
- Author(s)
  Minami Kenta、Arai-Aso Miyuki M.、Ogura-Kodama Yukari、Yamada Ayano、Kishida Kazumi、Sakase Mitsuhiro、Fukushima Moriyuki、Harayama Hiroshi
- Journal Title
  
  Animal Reproduction Science
  
  Volume: 218 Pages: 106479-106479
- DOI
  10.1016/j.anireprosci.2020.106479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22366
[Journal Article] Effects of digoxin on full-type hyperactivation in bovine ejaculated spermatozoa with relatively lower survivability for incubation with stimulators of cAMP signaling cascades2020
- Author(s)
  Saha Soma Rani、Sakase Mitsuhiro、Fukushima Moriyuki、Harayama Hiroshi
- Journal Title
  
  Theriogenology
  
  Volume: 154 Pages: 100-109
- DOI
  10.1016/j.theriogenology.2020.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22366
[Journal Article] Characteristics of bull sperm acrosome associated 1 proteins2020
- Author(s)
  Minami Kenta, Arai-Aso Miyuki M., Ogura-Kodama Yukari, Yamada Ayano, Kishida Kazumi, Sakase Mitsuhiro, Fukushima Moriyuki, Harayama Hiroshi
- Journal Title
  
  Animal Reproduction Science
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22366
[Journal Article] Identification of isoforms of calyculin A-sensitive protein phosphatases which suppress full-type hyperactivation in bull ejaculated spermatozoa2019
- Author(s)
  Arai Yuka, Sakase Mitsuhiro, Fukushima Moriyuki, Harayama Hiroshi
- Journal Title
  
  Theriogenology
  
  Volume: 129 Pages: 46-53
- DOI
  10.1016/j.theriogenology.2019.02.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Reconsideration of the evaluation criteria for bull ejaculated sperm motility in the context of rotation2018
- Author(s)
  Yamada Ayano, Sakase Mitsuhiro, Fukushima Moriyuki, Harayama Hiroshi
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 64 Issue: 5 Pages: 377-384
- DOI
  10.1262/jrd.2018-036
- NAID
  130007497640
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Flagellar hyperactivation of bull and boar spermatozoa (Invited review)2018
- Author(s)
  Harayama Hiroshi
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 17 Issue: 4 Pages: 442-448
- DOI
  10.1002/rmb2.12227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] 家畜精子鞭毛の超活性化運動に関する研究の現状（招待総説）2017
- Author(s)
  原山　洋，水野洋平
- Journal Title
  
  日本胚移植学雑誌
  
  Volume: 39 Pages: 159-167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Protein biomarkers for male artificial insemination subfertility in bovine spermatozoa2017
- Author(s)
  Hiroshi Harayama, Kenta Minami, Kazumi Kishida, Taichi Noda
- Journal Title
  
  Reproductive Medicine and Development
  
  Volume: 16 Issue: 2 Pages: 89-98
- DOI
  10.1002/rmb2.12021
- NAID
  120006716622
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Variation among individual bulls in the distribution of acrosomal tyrosine-phosphorylated proteins in epididymal and ejaculated spermatozoa2017
- Author(s)
  Miyuki M. Arai, Kenta Minami, Yukari Ogura, Nagisa Otsuka, Shohei Hama, Hiroshi Harayama, Mitsuhiro Sakase, Moriyuki Fukushima
- Journal Title
  
  Reproduction, Fertility and Development
  
  Volume: 29 Issue: 7 Pages: 1297-1305
- DOI
  10.1071/rd15483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Characterization of extracellular Ca2+ -dependent full-type hyperactivation in ejaculated boar spermatozoa preincubated with a cAMP analog2017
- Author(s)
  Nagisa Otsuka, Hiroshi Harayama
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 84 Issue: 11 Pages: 1203-1217
- DOI
  10.1002/mrd.22921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07990
[Journal Article] Involvement of cyclic AMP-dependent unique signaling cascades in the decrease of serine/threonine-phosphorylated proteins in boar sperm head2016
- Author(s)
  Ayane Isono, Shunsuke Tate, Kazumi Nakamura-Mori, Taichi Noda, Sho Ishikawa and Hiroshi Harayama
- Journal Title
  
  Theriogenology
  
  Volume: 85 Issue: 6 Pages: 1152-1160
- DOI
  10.1016/j.theriogenology.2015.11.031
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450394
[Journal Article] Individual differences in the distribution of acrosomal tyrosine-phosphorylated proteins in epididymal and ejaculated spermatozoa of Japanese Black bulls2016
- Author(s)
  Miyuki M. Arai, Kenta Minami, Yukari Ogura, Nagisa Otsuka, Shohei Hama, Hiroshi Harayama, Mitsuhiro Sakase and Moriyuki Fukushima
- Journal Title
  
  Reproduction, Fertility and Development
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450394
[Journal Article] Individual differences in the distribution of sperm acrosome associated 1 proteins among male patients of infertile couples; possible their impacts on outcomes of conventional in vitro fertilization2016
- Author(s)
  Kazumi Kishida, Hiroshi Harayama, Fuminori Kimura and Takashi Murakami
- Journal Title
  
  Zygote
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450394
[Journal Article] Distinct segment-specific functions of calyculin A-sensitive protein phosphatases in the regulation of cAMP-triggered events in ejaculated bull spermatozoa2015
- Author(s)
  Yohei Mizuno, Ayane Isono, Aya Kojima, Miyuki M. Arai, Taichi Noda, Mitsuhiro Sakase, Moriyuki Fukushima and Hiroshi Harayama
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 82 Issue: 3 Pages: 232-250
- DOI
  10.1002/mrd.22465
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450394, KAKENHI-PROJECT-25890013
[Journal Article] Effects of acrosomal conditions of frozen-thawed spermatozoa on the results of artificial insemination in Japanese Black cattle2015
- Author(s)
  Kazumi Kishida, Mitsuhiro Sakase, Kenta Minami, Miyuki M. Arai, Reiko Syoji, Namiko Kohama, Takayuki Akiyama, Akio Oka, Hiroshi Harayama and Moriyuki Fukushima
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 61 Issue: 6 Pages: 519-524
- DOI
  10.1262/jrd.2015-073
- NAID
  130005113570
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25450394
[Journal Article] Roles of extracellular Ca2+ in the occurrence of full-type hyperactivation in boar ejaculated spermatozoa pre-incubated to induce the cAMP-triggered events2015
- Author(s)
  Aya Kojima, Yuki Matsushita, Yukari Ogura, Sho Ishikawa, Taichi Noda, Tetsuma Murase and Hiroshi Harayama
- Journal Title
  
  Andrology
  
  Volume: 3 Issue: 2 Pages: 321-331
- DOI
  10.1111/andr.12005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25450394, KAKENHI-PROJECT-25890013
[Journal Article] Expression patterns of the activator type of cAMP-responsive element modulator in testicular germ cells of Japanese Black bulls2014
- Author(s)
  Taichi Noda, Kenta Minami, Aya Kojima, Yohei Mizuno, Ayane Isono, Mitsuhiro Sakase, Moriyuki Fukushima, Hiroshi Harayama
- Journal Title
  
  Theriogenology
  
  Volume: 81 Issue: 8 Pages: 1012-1020
- DOI
  10.1016/j.theriogenology.2014.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450394, KAKENHI-PROJECT-25890013
[Journal Article] Roles of Intracellular Cyclic AMP Signal Transduction in the Capacitation and Subsequent Hyperactivation of Mouse and Boar Spermatozoa2013
- Author(s)
  Hiroshi Harayama
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 59 Issue: 5 Pages: 421-430
- DOI
  10.1262/jrd.2013-056
- NAID
  130003381850
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25450394
[Journal Article] Relationship of protein tyrosine phosphorylation state with toleranceto frozen storage and the potential to undergo cyclic AMP-dependent hyperactivation in the spermatozoa of Japanese Black bulls2010
- Author(s)
  Harayama, H., Nishijima, K., Murase, T., Sakase, M., Fukushima, M
- Journal Title
  
  Mol. Reprod. Dev
  
  Volume: 77 Pages: 910-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580389
[Journal Article] Hyperactivated motility of frozen-thawed spermatozoa from fertile and subfertile Japanese black bulls induced by cyclic adenosine 3',5'-monophosphate analogue, cBiMPS.2010
- Author(s)
  Murase T, El-Kon I, Harayama H, Mukoujima K, Takasu M, Sakai K.
- Journal Title
  
  J Reprod Dev. Vol.56, No.1
  
  Pages: 36-40
- NAID
  10026323289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580310
[Journal Article] Relationship of protein tyrosine phosphorylation state with tolerance to frozen storage and the potential to undergo cyclic AMP-dependent hyperactivation in the spermatozoa of Japanese Black bulls2010
- Author(s)
  Hiroshi HARAYAMA
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 77 Pages: 910-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580389
[Journal Article] Relationship of protein tyrosine phosphorylation state with tolerance to frozen storage and the potential to undergo cyclic AMP-dependent hyperactivation in the spermatozoa of Japanese Black bulls2010
- Author(s)
  Hiroshi HARAYAMA
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 77 Pages: 910-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580310
[Journal Article] Relationship of protein tyrosine phosphorylation state with tolerance to frozen storage and the potential to undergo cyclic AMP-dependent hyperactivation in the spermatozoa of Japanese Black bulls2010
- Author(s)
  Harayama H, Nishijima K, Murase T, Sakase M, Fukushima M.
- Journal Title
  
  Mol Reprod Dev. Vol.77, No.10
  
  Pages: 910-921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580310
[Journal Article] Evidence of the existence of adenylyl cyclase 10 (ADCY10) ortholog proteins in the heads and connecting pieces of boar spermatozoa2010
- Author(s)
  Tate S, Nakamura K, Suzuki C, Noda T, Lee J, Harayama H.
- Journal Title
  
  J Reprod Dev. Vol.56, No.2
  
  Pages: 271-278
- NAID
  10026324672
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580310
[Journal Article] Changes of PICA and PDK1 in the principal piece of hoar spermatozoa treated with a cell-permeable cAMP analog to induce flagellar hyperactivation2008
- Author(s)
  Hiroshi, Harayama
- Journal Title
  
  Mol Reprod 75(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Journal Article] Changes of PKA and PDK1 in the principal piece of boar spermatozoa treated with a cell-permeable cAMP analog to induce flagellar hyperactivation.2008
- Author(s)
  Hiroshi Harayama
- Journal Title
  
  Mol Reprod Dev. 75(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580281
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate-dependent Protein Kinase C Activation Is Involved in the Hyperactivation of Boar Spermatozoa2006
- Author(s)
  Hiroshi, Harayama
- Journal Title
  
  Molecular Reproduction and Development (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate-dependent Protein Kinase C Activation Is Involved in the Hyperactivation of Boar Spermatozoa2006
- Author(s)
  HIROSHI HARAYAMA
- Journal Title
  
  Molecular Reproduction and Development (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate Stimulates Phospholipase Cγ1-Calcium Signaling via the Activation of Tyrosine Kinase in Boar Spermatozoa2005
- Author(s)
  Hiroshi, Harayama
- Journal Title
  
  Journal of Andrology 26-6
  
  Pages: 732-740
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate Stimulates Phospholipase Cγl-Calcium Signaling via the Activation of Tyrosine Kinase in Boar Spermatozoa2005
- Author(s)
  HIROSHI HARAYAMA
- Journal Title
  
  Journal of Andrology 第26巻・第6号
  
  Pages: 732-740
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3'5'-Monophosphate Stimulates Phospholipase Cγ1-Calcium Signaling via the Activation of Tyrosine Kinase in Boar Spermatozoa2005
- Author(s)
  HIROSHI HARAYAMA
- Journal Title
  
  Journal of Andrology 26・6
  
  Pages: 732-740
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3', 5'-Monophosphate-Induced Tyrosine Phosphorylation of Syk Protein Tyrosine Kinase in the Flagella of Boar Spermatozoa2004
- Author(s)
  HIROSHI HARAYAMA
- Journal Title
  
  Molecular Reproduction and Development 第69巻・第4号
  
  Pages: 436-447
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate-Induced Tyrosine Phosphorylation of Syk Protein Tyrosine Kinase in the Flagella of Boar Spermatozoa2004
- Author(s)
  HIROSHI HARAYAMA
- Journal Title
  
  Molecular Reproduction and Development 69・4
  
  Pages: 436-447
- Data Source
  KAKENHI-PROJECT-16580229
[Journal Article] A Cyclic Adenosine 3',5'-Monophosphate-Induced Tyrosine Phosphorylation of Syk Protein Tyrosine Kinase in the Flagella of Boar Spermatozoa2004
- Author(s)
  Hiroshi, Harayama
- Journal Title
  
  Molecular Reproduction and Development 69-4
  
  Pages: 436-447
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16580229
[Presentation] ウシ凍結保存精子でのCalyculin-A誘発性Full-type Hyperactivationの発生におけるストア作動性チャネルの関与2023
- Author(s)
  吉田早紀, 坂瀬充洋, 原山洋
- Organizer
  第116回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] ウシ凍結保存精子でのCalyculin-A 誘発性Full-type ハイパーアクチベーションの発生に及ぼすストア作動性チャネル非選択的阻害剤の影響2023
- Author(s)
  吉田早紀, 坂瀬充洋, 原山洋
- Organizer
  第73 回関西畜産学会大会
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] お父さん牛の精子がお母さんの卵子とどのように受精するのか？2023
- Author(s)
  原山洋
- Organizer
  第116回日本繁殖生物学会大会・市民公開講座「黒毛和牛をもっと増やそう！最新の繁殖生物学研究がお父さん牛にできること」
- Invited
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] 人工授精での受胎率の向上を目指して－ウシ（黒毛和種）精子の新規検査法の開発－2023
- Author(s)
  原山洋
- Organizer
  日本アンドロロジー学会第42回学術大会特別講演4
- Invited
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] ウシ凍結精子でのFull-typeハイパーアクチベーションの誘起のための処理条件の検討2022
- Author(s)
  原山洋, 宮本菜津子
- Organizer
  日本アンドロロジー学会第41回学術大会
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] Relationship of the SERCA activity with the time courses of occurrence of full-type hyperactivation in bovine sperm2022
- Author(s)
  Duritahala, Sakase M, Harayama H
- Organizer
  第115回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] Involvement of cytoplasmic Ca2+ and SERCAs in the occurrence of helical movement in bovine sperm2022
- Author(s)
  Duritahala, Harayama H
- Organizer
  日本アンドロロジー学会第41回学術大会
- Data Source
  KAKENHI-PROJECT-22K05951
[Presentation] ウシ射出精子の鞭毛運動に及ぼすNa+/K+-ATPase阻害剤Digoxinの影響2021
- Author(s)
  原山洋、Saha Soma Rani
- Organizer
  日本アンドロロジー学会第39回学術大会
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] ウシ精子における精密性状検査法の開発2020
- Author(s)
  原山洋
- Organizer
  令和2年度東海畜産学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] ブタ精子でのFull-type Hyperactivationの発生制御におけるカルモジュリンの役割2020
- Author(s)
  和田篤士、原山洋
- Organizer
  第113回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] 低繁殖症の雄ウシを検出するための精子分子性状検査法のマーカー「SPACA1タンパク質」の解析2019
- Author(s)
  南健太, 麻生美由紀, 山田綾乃, 岸田和美, 坂瀬充洋, 福島護之, 原山洋
- Organizer
  日本アンドロロジー学会第38回学術大会
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] 家畜精子の受精制御分子の探索と利用2019
- Author(s)
  原山洋
- Organizer
  第46回山梨大学発生工学研究センターセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] 黒毛和種精子におけるSPACA1タンパク質の特性解析2019
- Author(s)
  南健太, 麻生美由紀, 山田綾乃, 岸田和美, 坂瀬充洋, 福島護之, 原山洋
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] Involvement of digoxin-sensitive Na+/K+-ATPase in the regulation of bovine sperm motility2019
- Author(s)
  RANI Saha Soma, SAKASE Mitsuhiro, FUKUSHIMA Moriyuki, HARAYAMA Hiroshi
- Organizer
  第112回日本繁殖生物学会
- Data Source
  KAKENHI-PROJECT-19K22366
[Presentation] cAMP-PKAシグナル伝達活性の違いがウシ精子の運動様式に及ぼす影響－精子の活力検査における評価基準の見直し－2018
- Author(s)
  山田綾乃，坂瀬充洋，福島護之，原山　洋
- Organizer
  日本アンドロロジー学会第37回学術大会
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ウシ精子での細胞外Ca2+依存的なFull-typeハイパーアクチベーションの抑制に機能するカリクリンA感受性プロテインホスファターゼアイソフォームの特定2018
- Author(s)
  荒井佑香，原山　洋
- Organizer
  第6回関西生殖医学集談会
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] 活力検査法の改良を目的としたウシ射出精子の運動様式の観察2018
- Author(s)
  山田綾乃，坂瀬充洋，福島護之，原山　洋
- Organizer
  第111回日本繁殖生物学会大会
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] Calyculin A-sensitive protein phosphatases which are involved in the suppression for full-type hyperactivation of bovine sperm2017
- Author(s)
  Yuka Arai, Mitsuhiro Sakase, Moriyuki Fukushima, Hiroshi Harayama
- Organizer
  Fourth World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] Mechanism for the extracellular Ca2+-dependent occurrence of full-type hyperactivation in boar sperm treated with a cAMP analog2017
- Author(s)
  Nagisa Otsuka, Hiroshi Harayama
- Organizer
  Fourth World Congress of Reproductive Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] Advanced techniques for the reproduction in the cattle2017
- Author(s)
  Hiroshi Harayama
- Organizer
  UGSVS lecture
- Place of Presentation
  岐阜大学（岐阜県・岐阜市）
- Year and Date
  2017-02-10
- Invited
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ブタ精子での超活性化運動（Full-type HA）の開始におけるTRPC3チャネルの役割2017
- Author(s)
  大塚　渚，原山　洋
- Organizer
  第5回関西生殖医学集談会
- Place of Presentation
  ハービスPLAZA（大阪府・大阪市）
- Year and Date
  2017-03-04
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ウシ新鮮射出精子における先体チロシンリン酸化タンパク質の分布状態2016
- Author(s)
  荒井　美由紀，原山　洋
- Organizer
  第4回関西生殖医学集談会・第48回関西アンドロロジーカンファレンス合同研究会
- Place of Presentation
  ハービスPLAZA（大阪府・大阪市）
- Year and Date
  2016-03-05
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 先体タンパク質をマーカーとする哺乳類精子の分子性状検査法2016
- Author(s)
  原山　洋
- Organizer
  日本アンドロロジー学会35回学術大会シンポジウム1：男性不妊症の分子メカニズム
- Place of Presentation
  前橋テルサ（群馬県・前橋市）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ブタ精子におけるfull-type hyperactivationの開始制御へのTRPC3チャネルの関与2016
- Author(s)
  大塚　渚，原山　洋
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻布大学（神奈川県・相模原市）
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ウシ精子のハイパーアクチベーションを抑制するカリクリンA感受性プロテインホスファターゼの特定2016
- Author(s)
  荒井　佑香，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  第109回日本繁殖生物学会大会
- Place of Presentation
  麻布大学（神奈川県・相模原市）
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-16K07990
[Presentation] ブタ精子での先体反応誘起に伴う頭部タンパク質SPACA1の変化2016
- Author(s)
  小倉　有香里，原山　洋
- Organizer
  日本畜産学会第121回大会
- Place of Presentation
  日本獣医生命大学（東京都・武蔵野市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ウシ新鮮射出精子の分子性状における個体差　－先体チロシンリン酸化タンパク質と人工授精成績との関係－2015
- Author(s)
  荒井　美由紀，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  第108回日本繁殖生物学会大会
- Place of Presentation
  宮崎大学農学部（宮崎県・宮崎市）
- Year and Date
  2015-09-17
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 哺乳類の精子学　－運動の開始から受精まで－2015
- Author(s)
  原山　洋
- Organizer
  第35回関西生殖発生毒性フォーラム　基礎教育講演
- Place of Presentation
  弁天町 ORC200 生涯学習センター（大阪府・大阪市）
- Year and Date
  2015-04-11
- Invited
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 人工授精成績・体外受精成績に影響を与える哺乳類精子の先体タンパク質2015
- Author(s)
  原山　洋
- Organizer
  第60回日本生殖医学会学術講演会シンポジウム3 「受精に関する最近の話題」
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2015-04-27
- Invited
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 低繁殖症雄ウシの精子における欠陥型タンパク質の検出および特性解析2014
- Author(s)
  原山　洋
- Organizer
  受胎率向上SIG第1回会合
- Place of Presentation
  東京　東京大学
- Year and Date
  2014-12-20
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] Full-type hyperactivationの誘起に伴う家畜精子の頚部および中片部における変化2014
- Author(s)
  原山　洋，水野　洋平，小島　彩
- Organizer
  日本畜産学会第118回大会
- Place of Presentation
  つくば市　つくば国際会議場
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ヒト射出精子におけるSPACA1の検出　－先体での検出パターンと体外受精成績との相関性－2013
- Author(s)
  岸田　和美，原山　洋，木村　文則，村上　節
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  府中市　東京農工大学
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 人工授精で雌を受胎させにくい精子を産生する黒毛和種雄個体の検出法　－凍結保存後の精子先体の正常性と体内受精由来の移植可能胚率の関係－2013
- Author(s)
  坂瀬　充洋，小路　玲子，小浜　菜美子，秋山　敬孝，岡　章生，原山　洋，福島　護之
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  府中市　東京農工大学
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ブタ精子におけるカルパインの検出および機能解析2013
- Author(s)
  小島　彩，石川　翔，設楽　修，原山　洋
- Organizer
  第106回日本繁殖生物学会大会
- Place of Presentation
  府中市　東京農工大学
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ブタ精子での後帽部タンパク質の脱リン酸化および先体反応におけるcAMP-EPACシグナリングの役割2013
- Author(s)
  原山　洋
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  安田女子大学
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] ブタ精子での後帽部タンパク質の脱リン酸化および先体反応における cAMP-EPAC シグナリングの役割2013
- Author(s)
  礒野彩音,小島彩,高岸佑樹,石川翔,設楽修,原山洋
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  広島
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] ウシのハイパーアクチベーション精子における鞭毛タンパク質のリン酸化状態2013
- Author(s)
  原山　洋
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  安田女子大学
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] ウシ精子の鞭毛におけるタンパク質チロシンリン酸化および超活性化運動の誘起2013
- Author(s)
  水野　洋平，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  関西畜産学会第63回大会
- Place of Presentation
  彦根市　滋賀県立大学
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ウシのハイパーアクチベーション精子における鞭毛タンパク質のリン酸化状態2013
- Author(s)
  水野洋平,坂瀬充洋,福島護之, 原山洋
- Organizer
  日本畜産学会第116回大会
- Place of Presentation
  広島
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 黒毛和種精子における耐凍能マーカーの検出パターン2012
- Author(s)
  南健太,野田大地,礒野彩音,小島彩,水野洋平,坂瀬充洋,福島護之, 原山洋
- Organizer
  日本畜産学会第115回大会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 黒毛和種精子先体前部におけるチロシンリン酸化型SPACA1の解析－サンプル間差および精子成熟に伴う変化について－2012
- Author(s)
  原山　洋
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  筑波大学
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 哺乳類精子の細胞内cAMPシグナル伝達機構に関する研究2012
- Author(s)
  原山　洋
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  筑波大学
- Invited
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 黒毛和種精子先体前部におけるチロシンリン酸化型 SPACA1 の解析-サンプル間差および精子成熟に伴う変化について-2012
- Author(s)
  南健太,野田大地,礒野彩音,小島彩,水野洋平,坂瀬充洋,福島護之, 原山洋
- Organizer
  第105回日本繁殖生物学会大会
- Place of Presentation
  つくば
- Year and Date
  2012-09-05
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 黒毛和種精子における先体の耐凍性マーカーの特性解析2012
- Author(s)
  原山　洋
- Organizer
  第62回関西畜産学会大会
- Place of Presentation
  アバローム紀の国
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 黒毛和種精子における先体の耐凍性マーカーの特性解析2012
- Author(s)
  南健太,野田大地,礒野彩音,小島彩,水野洋平,坂瀬充洋,福島護之, 原山洋
- Organizer
  第62回関西畜産学会大会
- Place of Presentation
  和歌山
- Year and Date
  2012-09-14
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] 哺乳類精子の細胞内 cAMP シグナル伝達機構に関する研究2012
- Author(s)
  原山洋
- Organizer
  第105回日本繁殖生物学会大会、2012 年度日本繁殖生物学会賞学術賞受賞者講演(招待講演)
- Place of Presentation
  つくば
- Year and Date
  2012-09-06
- Data Source
  KAKENHI-PROJECT-23658225
[Presentation] ブタ精子でのcAMP依存的な鞭毛超活性化運動に及ぼすカルモジュリンアンタゴニストおよびカルパイン阻害剤の影響2011
- Author(s)
  原山洋, 野田大地, 設楽修
- Organizer
  第136回日本生殖医学会関西支部集談会・第42回関西アンドロロジーカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子でのcAMP依存的な鞭毛超活性化運動に及ぼすカルモシュリンアンタゴニストおよびカルパイン阻害剤の影響2011
- Author(s)
  原山洋
- Organizer
  第136回日本生殖医学会関西支部集談会
- Place of Presentation
  ハービスPLAZA(大阪府)
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精巣におけるcAMP依存性転写調節因子CREMτの発現2010
- Author(s)
  野田大地, 設楽修, 原山洋
- Organizer
  日本畜産学会第112回大会
- Place of Presentation
  東京
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Identification of cAMP responsive element modulator (CREM) isoforms of the porcine testis2010
- Author(s)
  野田大地, 設楽修, 原山洋
- Organizer
  11th International Symposium on Spermatology
- Place of Presentation
  那覇
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Immunodetection patterns of tyrosine-phosphorylated proteins in the head of frozen-thawed spermatozoa of Japanese Black bulls2010
- Author(s)
  原山洋, 村瀬哲磨, 坂瀬充洋, 福島護之
- Organizer
  11th International Symposium on Spermatology
- Place of Presentation
  那覇
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Subfertility in Japanese Black bulls and new methods to detect abnormal functionality of spermatozoa2010
- Author(s)
  Murase T., Mukoujima K., Harayama H., Hoshino Y., Kato T.
- Organizer
  International Symposium of Declining Fertility in Dairy Cows in the World ; its Causes and Possible Solutions
- Place of Presentation
  宮崎
- Year and Date
  2010-01-30
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタの精子形成関連タンパク質の発現を制御するcAMPシグナリング構成分子の同定2010
- Author(s)
  野田大地, 原山洋
- Organizer
  第135回日本生殖医学会関西支部集談会・第40回関西アンドロロジーカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子中片部のAMPKはcAMP依存性ハイパーアクチベーションの発現制御に関与する2010
- Author(s)
  原山洋, 野田大地, 設楽修
- Organizer
  日本アンドロロジー学会第29回学術大会
- Place of Presentation
  東京
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Desalting of boar seminal plasma by gel filtration2010
- Author(s)
  Murase, T., Imaeda, N., Yamada, H., Harayama, H., Takasu, M., Taguchi, K., and Katoh, T.
- Organizer
  11th International Symposium on Spermatology
- Place of Presentation
  Okinawa
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-21580389
[Presentation] Immunodetection patterns of tyrosine-phosphorylated proteins in the head of frozen-thawed spermatozoa of Japanese Black bulls2010
- Author(s)
  Hiroshi HARAYAMA
- Organizer
  11th International Symposium on Spermatology
- Place of Presentation
  沖縄コンベンションセンター(沖縄県)(招待講演)
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子中片部のAMPKはcAMP依存性ハイパーアクチベーションの発現制御に関与する2010
- Author(s)
  原山洋
- Organizer
  日本アンドロロジー学会第29回学術大会
- Place of Presentation
  日本獣医生命科学大学(東京都)
- Year and Date
  2010-07-30
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ウシ精巣におけるアデニル酸シクラーゼ10 (ADCY10) mRNAsのスプライスバリアントの検出2010
- Author(s)
  綿井佑輔, 野田大地, 坂瀬充洋, 福島護之, 原山洋
- Organizer
  第135回日本生殖医学会関西支部集談会・第40回関西アンドロロジーカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Detection of Soluble Adenylyl Cyclase(ADCY10)Homolog Proteins in Boar Spermatozoa2009
- Author(s)
  原山洋
- Organizer
  American Society of Andrology 34^<th> Annual Meeting
- Place of Presentation
  ハイアットリージェンシーフィラデルフィアアットペンズランディング(アメリカ合衆国)
- Year and Date
  2009-04-05
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] 哺乳類精子における部位特異的なcAMPシグナリング2009
- Author(s)
  原山洋
- Organizer
  第8回受精シンポジウム「精子研究の最前線」(日本動物学会第80回大会)
- Place of Presentation
  静岡
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子におけるADCY10の検出2009
- Author(s)
  中村和美, 鈴木千尋, 田手俊輔, 李智博, 原山洋
- Organizer
  日本アンドロロジー学会第28回学術大会
- Place of Presentation
  富山
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精巣におけるcAMP依存性転写調節因子(CREM)ファミリーアイソフォームの発現2009
- Author(s)
  野田大地, 設楽修, 原山洋
- Organizer
  日本アンドロロジー学会第28回学術大会
- Place of Presentation
  富山
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] cAMPアナログ処理により鞭毛超活性化運動が誘起されたブタ精子でのAMPKaサブユニットの分子変化2009
- Author(s)
  原山洋
- Organizer
  第38回関西アンドロロジーカンフアレンス
- Place of Presentation
  大阪市
- Year and Date
  2009-03-14
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Detection of soluble adenylyl cyclase (ADCY10) homolog proteins in boar spermatozoa2009
- Author(s)
  中村和美, 鈴木千尋, 田手俊輔, 李智博, 原山洋
- Organizer
  34th Annual Meeting of the American Society of Andrology
- Place of Presentation
  Philadelphia, PA, USA
- Year and Date
  2009-04-05
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] 哺乳類精子での頚部特異的なcAMPシグナリングによるバイパーアクチベーションの制御2009
- Author(s)
  原山洋
- Organizer
  第40回精子研究会
- Place of Presentation
  吹田市
- Year and Date
  2009-01-10
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子におけるADCY10の検出2009
- Author(s)
  原山洋
- Organizer
  日本アンドロロジー学会第28回学術大会
- Place of Presentation
  ANAクラウンプラザホテル富山(富山県)
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子でのハイパーアクチベーションの発現制御における解糖系の役割2009
- Author(s)
  原山洋
- Organizer
  日本畜産学会第110回大会
- Place of Presentation
  藤沢市
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] 哺乳類精子の頚部特異的なcAMPシグナリングによるハイパーアクチベーションの制御2009
- Author(s)
  原山洋
- Organizer
  第40回精子研究会シンポシウム
- Place of Presentation
  吹田
- Year and Date
  2009-01-10
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子でのハイパーアクチベーションの発現制御における解糖系の役割2009
- Author(s)
  原山洋, 中村和美, 三宅正史
- Organizer
  日本畜産学会第110回大会
- Place of Presentation
  藤沢
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] 哺乳類精子における部位特異的なcAMPシグナリング2009
- Author(s)
  原山洋
- Organizer
  日本動物学会第80回大会(第8回受精シンポジウム精子研究の最前線)
- Place of Presentation
  静岡県コンベンションアーツセンターグランシップ(静岡県)
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] cAMPアナログ処理により鞭毛超活性化運動が誘起されたブタ精子でのAMPKサブユニットの分子変化2009
- Author(s)
  原山洋, 野田大地, 三宅正史
- Organizer
  第134回日本生殖医学会関西支部集談会・第38回関西アンドロロジーカンファレンス
- Place of Presentation
  大阪
- Year and Date
  2009-03-14
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] 低受胎率を示した黒毛和種あるいは正常な個体における凍結-融解精子鞭毛の超活性化運動2008
- Author(s)
  村瀬哲磨, Ismail El-kon, 向島幸司, 原山洋, 高須正規, 酒井謙司
- Organizer
  日本繁殖生物学会第101回大会
- Place of Presentation
  福岡
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] cAMP-Epacシグナリングを介したブタ精子キャパシテーションの新規制御メカニズム2008
- Author(s)
  中村和美, 田手俊輔, 原山洋
- Organizer
  日本アンドロロジー学会第27回学術大会
- Place of Presentation
  京都
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] ブタ精子頭部での細胞内カルシウム濃度上昇における可溶化型アデニル酸シクラーゼの役割2008
- Author(s)
  中村和美, 鈴木千尋, 田手俊輔, 原山洋
- Organizer
  日本繁殖生物学会第101回大会
- Place of Presentation
  福岡
- Year and Date
  2008-09-18
- Data Source
  KAKENHI-PROJECT-20580310
[Presentation] Cyclic AMP-induced inactivation of PDK1 is linked to the enhancement of protein tyrosine phosphorylation and flagellar hyperactivation in boar spermatozoa2008
- Author(s)
  Hiroshi, Harayama
- Organizer
  33rd Annual Meeting of American Society of Andrology
- Place of Presentation
  Albuquerque
- Year and Date
  2008-04-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] ブタ精子の部位特異的な細胞内cAMPシグナリング:ハイパーアクチベーション誘起に伴う鞭毛主部でのPKAおよびPDK1のcAMP依存的な変化2007
- Author(s)
  原山洋
- Organizer
  第100回日本繁殖生物学会大会
- Place of Presentation
  東京
- Year and Date
  2007-10-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] Segment-specific cAMP signaling in boar sperm cAMP-PICA-PKC signaling of the connecting piece is involved in the regulation of exhibition of flagellar hyperactivation2007
- Author(s)
  Hiroshi, Harayama
- Organizer
  264 Annual Meeting of Japanese Society of Andrology
- Place of Presentation
  Urayasu
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] ブタ精子の部位特異的な細胞内cAMPシグナリング:頚部のcAMP-PKA-PKCシグナリングはハイパーアクチベーションの発現調節に関与する2007
- Author(s)
  原山洋
- Organizer
  日本アンドロロジー学会第26回学術大会
- Place of Presentation
  浦安
- Year and Date
  2007-07-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] Segment-specific cAMP signaling in boar sperm cAMP-dependent changes of PICA and PDK1 in the principal piece during the induction of flagellar hyperactivation2007
- Author(s)
  Hiroshi, Harayama
- Organizer
  100th Annual Meeting of Japanese Society of Animal Reproduction
- Place of Presentation
  Tokyo
- Year and Date
  2007-10-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] The cAMP/PICA signaling-dependent activation of PKC is involved in the exhibition of flagellar hyperactivation in boar sperm2006
- Author(s)
  Hiroshi, Harayama
- Organizer
  99th Annual Meeting of Japanese Society of Animal Reproduction
- Place of Presentation
  Nagoya
- Year and Date
  2006-09-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] ブタ精子におけるcAMP-PKAシグナリング依存的なPKCの活性化は鞭毛超活性化運動の発現制御に関与する2006
- Author(s)
  原山洋
- Organizer
  第99回日本繁殖生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2006-09-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18580281
[Presentation] ウシ凍結精子での先体損傷・離脱に伴うIZUMO1の変化
- Author(s)
  福田　匡起，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  日本畜産学会第119回大会
- Place of Presentation
  宇都宮市　宇都宮大学
- Year and Date
  2015-03-27 – 2015-03-30
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ブタ精子の鞭毛に分布するカルパイン2の役割
- Author(s)
  小島　彩，原山　洋
- Organizer
  第2回関西生殖医学集談会
- Place of Presentation
  大阪市　ハービスPLAZA
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ウシ凍結保存精子における先体の損傷・離脱が頭部でのIZUMO1の分布に及ぼす影響
- Author(s)
  福田　匡起，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  第107回日本繁殖生物学会大会
- Place of Presentation
  帯広市　帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ブタ精子での先体反応に伴う頭部タンパク質「SPACA1」の分布および分子マスの変化
- Author(s)
  小倉　有香里，高岸　佑樹，小島　彩，石川　翔，原山　洋
- Organizer
  第107回日本繁殖生物学会大会
- Place of Presentation
  帯広市　帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ウシ精巣におけるcAMP依存性転写調節因子CREMの発現パターンの解析
- Author(s)
  野田　大地，南　健太，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  第107回日本繁殖生物学会大会
- Place of Presentation
  帯広市　帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] ヒト射出精子の頭部におけるSPACA1の分布状態の個体差－先体主部での分布状態と体外受精成績との関係－
- Author(s)
  岸田　和美，原山　洋，木村　文則，村上　節
- Organizer
  第2回関西生殖医学集談会
- Place of Presentation
  大阪市　ハービスPLAZA
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 黒毛和種精子でのチロシンリン酸化タンパク質の分布状態が先体の安定性に及ぼす影響
- Author(s)
  荒井　美由紀，南　健太，小倉　有香里，坂瀬　充洋，福島　護之，原山　洋
- Organizer
  第107回日本繁殖生物学会大会
- Place of Presentation
  帯広市　帯広畜産大学
- Year and Date
  2014-08-21 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] 家畜精子のハイパーアクチベーションに先立つ部位特異的なキャパシテーション
- Author(s)
  原山　洋
- Organizer
  日本アンドロロジー学会第33回学術大会シンポジウム 1 「Capacitation の最前線を極める」
- Place of Presentation
  軽井沢町　軽井沢プリンスホテルウエスト
- Year and Date
  2014-06-12 – 2014-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-25450394
[Presentation] The association between spatial distribution patterns of SPACA1 in human ejaculated sperms and outcomes of conventional IVF
- Author(s)
  Kazumi Kishida, Hiroshi Harayama, Fuminori Kimura and Takashi Murakami
- Organizer
  World Congress of Reproductive Biology 2014
- Place of Presentation
  EICC, Edinburgh
- Year and Date
  2014-09-02 – 2014-09-04
- Data Source
  KAKENHI-PROJECT-25450394

1. MIYAKE Masashi (60093316)

# of Collaborated Projects: 7 results

# of Collaborated Products: 2 results
2. MURASE Tetsuma (30303514)

# of Collaborated Projects: 7 results

# of Collaborated Products: 8 results
3. 中嶋昭雄 (70397818)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. FUKUSHIMA Moriyuki (60463395)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. KATO Seishiro (90026386)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 坂瀬充洋 (70463396)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
7. 川手憲俊 (80221901)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 古山敬祐 (50611026)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MIYANO Takashi (80200195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KANNAN Yasuyuki (60031192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Noda Taichi (50712551)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 西村亮 (20704901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIMIZU Kenji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUREBAYASHI Satoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TOMINAGA Keiichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 富永敬一郎

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HARAYAMA HIROSHI 原山 洋

HARAYAMA Hiroshi 原山 洋

Research Projects

Research Products

Co-Researchers

ウシの人工授精成績の向上を目的とした先体反応発生能力を指標とする精子検査法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment and spread of the new assay for sperm flagellar function to improve artificial insemination results in the cattlePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of 3-dimensional rotation for the purpose of reconsidering criteria for the evaluation of flagellar functions in bull spermPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization and utilization of SPACA1 proteins for the purpose of establishment of a new method to predict freezability of bull sperm before cryopreservationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of methods to evaluate molecular characteristics of livestock spermatozoa by the detection of aberrant fertility-regulating factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Enhancement of the tolerance to the storage in boar and mouse spermatozoa by the re-maturation in vitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Targeted therapy for defect of fertilizing ability in the spermatozoa from subfertile livestockPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

HARAYAMA HIROSHI 原山洋

HARAYAMA Hiroshi 原山洋

[Book] 繁殖生物学改訂版（第2版）（第5章3 受精 pp. 228～237）2020

[Book] 発生生物学基礎から応用への展開 (第5章3節)2019