KITAURA JIRO 北浦次郎

… Alternative Names

Researcher Number	30282651
Other IDs
Affiliation (Current)	2019: 順天堂大学, 医学(系)研究科(研究院), 先任准教授
Affiliation (based on the past Project Information) *help	2014 – 2019: 順天堂大学, 医学(系)研究科(研究院), 先任准教授 2015 – 2016: 順天堂大学, 医学(系)研究科(研究院), 准教授 2013: 東京大学, 医科学研究所, 准教授 2007 – 2012: The University of Tokyo, The Institute of Medical Science, Research Associate 2010: 東北大学, 医科学研究所, 助教 2005 – 2006: 東京大学, 医科学研究所, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Collagenous pathology/Allergology / Biological Sciences Except Principal Investigator Hematology / Biological Sciences
Keywords	Principal Investigator アレルギー / 炎症 / マスト細胞 / 抑制型受容体 / 脂質 / 免疫学 / ノックアウトマウス / ペア型免疫レセプター / ミエロイド / 自己免疫 … More Except Principal Investigator 発現クローニング / LMIR / MDS / 遺伝子 / 白血病 / エピジェネティクス / ASXL1 / EZH2 / レセプター / アポトーシス / ノックアウトマウス / 免疫 / 免疫レセプター / MAIR / マスト細胞 / ヒストン / 単球 / 好中球 / PIR / レトロウィルスベクター / AML1 / 遺伝子変異 / レトロウイルスベクター / レトロゥィルスベクター / 血液腫瘍学 / 癌 / シグナル伝達 / 発現制御 / 内科 / 骨随意形成症候群 / miRNA / マウス骨髄移植モデル / ABC-G2 / 骨髄ストローマ細胞 / クローン性造血 / 骨髄異形性症候群 / ノックインマウス / 造血器腫瘍 Less

Identification of novel mutations in patients with pyroptosis-associated rare disease and clarification of the pathogenesisPrincipal InvestigatorOngoing
- Principal Investigator
  
  北浦次郎
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
Analysis of the mechanism by which lipid-recognizing paired immnue receptors regulate inflammationPrincipal InvestigatorOngoing
- Principal Investigator
  
  北浦次郎
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
The development of anti-allergy therapies targeting several inhibitory receptorsPrincipal Investigator
- Principal Investigator
  
  Kitaura Jiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Comprehensive elucidation of MDS (myelodysplastic syndromes) pathogenesis
- Principal Investigator
  
  Kitamura Toshio
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analysis of the mechanisms by which mast cell activation is regulated by paired receptors LMIR3 and LMIR7Principal Investigator
- Principal Investigator
  
  Kitaura Jiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University
Integrative elucidation of molecular mechanisms for leukemogenesis: Identification and analyses of mutations with novel categories.
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
What is a ligand fro LMIR, regulating allery and inflammation?Principal Investigator
- Principal Investigator
  
  KITAURA JIRO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
ペア型免疫レセプターファミリーLMIR/CLM/MAIRの機能解析とリガンド同定
- Principal Investigator
  
  北村俊雄
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Toward the comprehensive understanding of molecular mechanisms of hematopoietic malignancies
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Analysis of in vivo functions of LMIR3/4/5Principal Investigator
- Principal Investigator
  
  KITAURA Jiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
アポトーシス細胞を認識する新しいレセプターLMIR3/4の機能解析
- Principal Investigator
  
  KITAMURA Toshio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
What is the function of integrin allb in mast cell?Principal Investigator
- Principal Investigator
  
  KITAURA Jiro
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2005 Other

All Journal Article Presentation Book

[Book] マスト細胞の活性化とLMIR3(「抑制型レセプターであるLMIR3はマスト細胞においてFcR.と会合し、リポポリサッカライドによる反応を増強する」)532010
- Author(s)
  伊沢久未、北浦次郎、北村俊雄
- Publisher
  臨床免疫\アレルギー科
- Data Source
  KAKENHI-PROJECT-20390279
[Book] Leukocyte mono-Ig like receptor 3 (LMIR3)によるマスト細胞の活性化と抑制化542010
- Author(s)
  伊沢久未、北浦次郎、北村俊雄
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PROJECT-20390279
[Book] 活性型レセプターLMIR5によるマスト細胞の機能制御-マウスおよびヒトLMIR5の相違522009
- Author(s)
  山西吉典、北浦次郎、北村俊雄
- Publisher
  臨床免疫・アレルギー科
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] High expression of ABCG2 induced by EZH2 disruption plays pivotal roles in MDS pathogenesis2017
- Author(s)
  Kawabata K C、Hayashi Y、Inoue D、Meguro H、Sakurai H、Fukuyama T、Tanaka Y、Asada S、Fukushima T、Nagase R、Takeda R、Harada Y、Kitaura J、Goyama S、Harada H、Aburatani H、Kitamura T
- Journal Title
  
  Leukemia
  
  Volume: 32 Pages: 419-428
- DOI
  10.1038/leu.2017.227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09831, KAKENHI-PUBLICLY-17H05634, KAKENHI-PROJECT-15H03137, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-15K09460
[Journal Article] Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation2017
- Author(s)
  Shiba E, Izawa K, Kaitani A, Isobe M, Maehara A, Uchida K, Maeda K, Nakano N, Ogawa H, Okumura K, Kitamura T, Shimizu T, Kitaura J
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 292 Pages: 2924-2932
- DOI
  10.1074/jbc.m116.768366
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K15376, KAKENHI-PROJECT-15K19677, KAKENHI-PROJECT-15K09784
[Journal Article] Pharmacologic inhibition of Notch signaling suppresses food antigen-induced mucosal mast cell hyperplasia.2017
- Author(s)
  Honjo A, Nakano N, Yamazaki S, Hara M, Uchida K, Kitaura J, Nishiyama C, Yagita H, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 139 Pages: 987-996
- DOI
  10.1016/j.jaci.2016.05.046
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-16K15092, KAKENHI-PROJECT-17K10192, KAKENHI-PROJECT-15K09699, KAKENHI-PROJECT-26461643
[Journal Article] Ceramido-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation.2016
- Author(s)
  Matsukawa T, Izawa K, Isobe M, Takahashi M, Maehara A, Yamanishi Y, Kaitani A, Okumura K, Teshima T, Kitamura T, Kitaura J
- Journal Title
  
  Gut.
  
  Volume: 印刷中 Pages: 777-787
- DOI
  10.1136/gutjnl-2014-308900
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-14J00014, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-25893050, KAKENHI-PROJECT-26893063, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K15376, KAKENHI-PROJECT-15K19677, KAKENHI-PROJECT-15K20969
[Journal Article] SETBP1 Mutations Drive Leukemic Transformation in ASXL1-Mutated MDS.2015
- Author(s)
  Inoue D, Kitaura J, Matsui H, Hou HA, Chou WC, Nagamachi A, Kawabata KC, Togami K, Nagase R, Horikawa S, Saika M, Micol JB, Hayashi Y, Harada Y, Harada H, Inaba T, Tien HF, Abdel-Wahab O, Kitamura T.
- Journal Title
  
  Leukemia
  
  Volume: 29(4) Pages: 847-57
- DOI
  10.1038/leu.2014.301
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J09414, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-26893051, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-26670465, KAKENHI-PROJECT-26860735
[Journal Article] he Transcription Factor Ehf Is Involved in TGF-β-Induced Suppression of FcεRI and c-Kit Expression and FcεRI-Mediated Activation in Mast Cells.2015
- Author(s)
  Yamazaki S, Nakano N, Honjo A, Hara M, Maeda K, Nishiyama C, Kitaura J, Ohtsuka Y, Okumura K, Ogawa H, Shimizu T
- Journal Title
  
  J Immunol.
  
  Volume: 195(7) Pages: 3427-3425
- DOI
  10.4049/jimmunol.1402856
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09784, KAKENHI-PROJECT-26461494, KAKENHI-PROJECT-26461643, KAKENHI-PROJECT-15K15376, KAKENHI-PROJECT-26293087, KAKENHI-PROJECT-26293231
[Journal Article] The phosphatidylserine and phosphatidylethanolamine receptor CD300a binds dengue virus and enhances infection.2015
- Author(s)
  Carnec X, Meertens L, Dejarnac O, Perera-Lecoin M, Lamine Hafirassou M, Kitaura J, Ramdasi R, Schwartz O, Amara A
- Journal Title
  
  J Virol.
  
  Volume: 90 Pages: 92-102
- DOI
  10.1128/jvi.01849-15
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15376, KAKENHI-PROJECT-26293231
[Journal Article] A C-terminal mutant of C/EBP (C/EBPa-Cm) down-regulates the Csf1r, a potent accelerator in the progression of AML with C/EBPa-Cm2015
- Author(s)
  Togami, K., Kitaura, J., Uchida, T., Inoue, D., Nishimura, K., Kawabata, K.C., Nagase, R., Horikawa, S., Izawa, K., Fukuyama, T., Nakahara, F., Oki, T., Harada, Y., Harada, H., Aburatani, H. and Kitamura, T.
- Journal Title
  
  Exp Hematol.
  
  Volume: 43 Pages: 300-308
- DOI
  10.1016/j.exphem.2014.11.011
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249039, KAKENHI-PUBLICLY-25118709, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-15K09460, KAKENHI-PROJECT-15H04855, KAKENHI-PROJECT-13J09414, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-26670465
[Journal Article] Hes1 upregulation contributes to the development of FIP1L1-PDGRA-positive leukemia in blast crisis2014
- Author(s)
  Uchida T, Kawabata KC, Kitamura T., et al.
- Journal Title
  
  Experimental hematology
  
  Volume: S0301-472X(14) Pages: 56-3
- DOI
  10.1016/j.exphem.2014.01.009
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J09414, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422
[Journal Article] LMIR3によるマスト細胞活性化の制御とアレルギー炎症の抑制2014
- Author(s)
  北浦次郎, 伊沢久未, 北村俊雄
- Journal Title
  
  炎症と免疫
  
  Volume: Vol. 22, No. 2 Pages: 90-93
- URL
  http://www.sentan.com/cgi-bin/db_n.cgi?mode=view_backno&no=1021
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] Sphingomyelin and ceramide are physiological ligands for human LMIR3/CD300f, inhibiting FcεRI-mediated mast cell activation.2014
- Author(s)
  Izawa, K., Isobe, M., Matsukawa, T., Ito, S., Maehara, A., Takahashi, M., Yamanishi, Y., Kaitani, A., Oki, T., Okumura, K., *Kitamura, T., and *Kitaura, J.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 133 Pages: 270-273
- DOI
  10.1016/j.jaci.2013.08.008
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-25893050, KAKENHI-PROJECT-26293087
[Journal Article] LMIR3によるマスト細胞活性化の制御とアレルギー炎症の抑制2014
- Author(s)
  北浦次郎、伊沢久未、北村俊雄
- Journal Title
  
  炎症と免疫
  
  Volume: 22 (2) Pages: 90-93
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP9 up-regulation in leukemic cells.2014
- Author(s)
  Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata KC, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T.
- Journal Title
  
  blood
  
  Volume: 123(25) Pages: 3932-3942
- DOI
  10.1182/blood-2013-01-476747
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-13J09414, KAKENHI-PLANNED-22112007, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249039, KAKENHI-PROJECT-24591382, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422, KAKENHI-PROJECT-25860521, KAKENHI-PROJECT-26293231, KAKENHI-PROJECT-26461415
[Journal Article] CD300b/LMIR5と炎症2013
- Author(s)
  北浦次郎、山西吉典、北村俊雄
- Journal Title
  
  医学のあゆみ
  
  Volume: 245 (3) Pages: 229-233
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] The shortest isoform of C/EBPbeta, Liver inhibitory protein (LIP), collaborates with Evi1 to induce AML in a mouse BMT model.2013
- Author(s)
  Okochi, N., Yoshimi, A., Sato, T., Ikeda, T., Kumano, K., Taoka, K., Sato, Y., Shinohara, A., Tsuruta, A., Masuda, A., Yokota, H., Yatomi, Y., Takahashi, K., Kitaura, J., Kitamura, T. and Kurokawa, M
- Journal Title
  
  Blood
  
  Volume: 121 Pages: 4142-4155
- DOI
  10.1182/blood-2011-07-368654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24790961, KAKENHI-PROJECT-24790964, KAKENHI-PUBLICLY-23130503
[Journal Article] LMIR3(CD300f)によるマスト細胞活性化の抑制2013
- Author(s)
  北浦次郎, 伊沢久未, 北村俊雄
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: Vol. 160, No. 5 Pages: 478-485
- URL
  http://www.kahyo.com/category/A1-MA
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] 抑制型レセプターLMIR3/CD300fはセラミドを認識する2013
- Author(s)
  北浦次郎、伊沢久未、北村俊雄
- Journal Title
  
  生化学
  
  Volume: 185 (12) Pages: 1071-1075
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] 抑制型レセプターLMIR3/CD300fはセラミドを認識する2013
- Author(s)
  北浦次郎, 伊沢久未, 北村俊雄
- Journal Title
  
  生化学
  
  Volume: Vol. 185, No. 12 Pages: 1071-1075
- URL
  http://www.jbsoc.or.jp/journal
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] CD300b/LMIR5と炎症2013
- Author(s)
  北浦次郎, 山西吉典, 北村俊雄
- Journal Title
  
  医学のあゆみ
  
  Volume: Vol. 245, No. 3 Pages: 229-233
- URL
  https://www.ishiyaku.co.jp/magazines/ayumi/
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] Myelodysplastic syndromes are induced by histone methylation-altering ASXL1 mutations2013
- Author(s)
  Inoue, D
- Journal Title
  
  J Clin Invest.
  
  Volume: 123 Pages: 4627-40
- DOI
  10.1172/jci70739
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23310183, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24591398, KAKENHI-PUBLICLY-25118716, KAKENHI-PROJECT-25461422
[Journal Article] LMIR3(CD300f)によるマスト細胞活性化の抑制2013
- Author(s)
  北浦次郎、伊沢久未、北村俊雄
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 160 (5) Pages: 478-485
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] Human CD300C Delivers an Fc Receptor-γ-dependent Activating Signal in Mast Cells and Monocytes and Differs from CD300A in Ligand Recognition.2013
- Author(s)
  Takahashi M, Izawa K, Kashiwakura JI, Yamanishi Y, Enomoto Y, Kaitani A, Maehara A, Isobe M, Ito S, Matsukawa T, Nakahara F, Oki T, Kajikawa M, Ra C, Okayama Y, Kitamura T, Kitaura J.
- Journal Title
  
  J Biol Chem
  
  Volume: 288(11) Pages: 7662-6775
- DOI
  10.1074/jbc.m112.434746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07783, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257
[Journal Article] A Soluble Form of LMIR5/CD300b Amplifies Lipopolysaccharide-Induced Lethal Inflammation in Sepsis.2012
- Author(s)
  Yoshinori Yamanishi
- Journal Title
  
  J Immunol
  
  Volume: 189 Pages: 1773-1779
- DOI
  10.4049/jimmunol.1201139
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-24249047, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002
[Journal Article] LMIRの機能とリガンド2012
- Author(s)
  北浦次郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 59 Pages: 259-264
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] アレルギーとマスト細胞<抑制型レセプターLMIR3について>2012
- Author(s)
  北浦次郎, 伊沢久未, 北村俊雄
- Journal Title
  
  アレルギーの臨床
  
  Volume: Vol. 32, No. 12 Pages: 28-32
- URL
  http://www.hokuryukan-ns.co.jp/magazines/allergy.html
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] MicroRNA-125b-1 accelerates a C-terminal mutant of C/EBPa (C/EBPa-C(m)) -induced myeloid leukemia2012
- Author(s)
  Enomoto, Y., Kitaura, J., Shimanuki, M., Kato, N., Nishimura, K., Takahashi, M., Nakamura, H., Kitamura, T., and Sonoki T
- Journal Title
  
  Int. J. Hematol
  
  Volume: 96 Pages: 334-341
- DOI
  10.1007/s12185-012-1143-5
- Data Source
  KAKENHI-PROJECT-23249051
[Journal Article] CD300/LMIRファミリーとマスト細胞2012
- Author(s)
  北浦次郎
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 58 Pages: 190-196
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide2012
- Author(s)
  Izawa K, Yamanishi Y, Maehara A, Takahashi M, Isobe M, Ito S, Kaitani A, Matsukawa T, Matsuoka T, Nakahara F, Oki T, Kiyonari H, Abe T, 0kumura K, Kitamura T, Kitaura J.
- Journal Title
  
  Immunity
  
  Volume: 16;37(5) Pages: 827-39
- DOI
  10.1016/j.immuni.2012.08.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07783, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23390260, KAKENHI-PROJECT-23791074, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002
[Journal Article] アレルギーとマスト細胞＜抑制型レセプターLMIR3について＞2012
- Author(s)
  北浦次郎
- Journal Title
  
  アレルギーの臨床
  
  Volume: 32 Pages: 28-32
- Data Source
  KAKENHI-PROJECT-23390257
[Journal Article] Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell2012
- Author(s)
  Oki T, Kitaura J, Watanabe-Okochi N, Nishimura K, Maehara A, Uchida T, Komeno Y, Nakahara F, Harada Y, Sonoki T, Harada H, Kitamura T
- Journal Title
  
  Leukemia
  
  Volume: (in press) Pages: 1038-1045
- DOI
  10.1038/leu.2011.328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591206, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23791074, KAKENHI-PROJECT-24591398, KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PUBLICLY-23118518
[Journal Article] Two types of C/EBP. mutations play distinct but collaborative roles in leukemogenesis : Lessonsfrom clinical data and BMT models.2011
- Author(s)
  Kato, N., Kitaura, J., Doki, N., Komeno, Y., Watanabe-Okochi, N., Togami, K., Nakahara, F., Oki, T., Enomoto, Y., Fukuchi, Y., Nakajima, H., Harada, Y., Harada, H., Kitamura, T.
- Journal Title
  
  Blood. 117
  
  Pages: 221-233
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Two types of C/EBP mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models2011
- Author(s)
  Kato, N
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 221-233
- DOI
  10.1182/blood-2010-02-270181
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22591038, KAKENHI-PROJECT-23249051
[Journal Article] El/miR-125b transgenic mice develop lethal B-cell malignancies2011
- Author(s)
  Enomoto, Y
- Journal Title
  
  Leukemia
  
  Volume: 25 Pages: 1849-1856
- DOI
  10.1038/leu.2011.166
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22118001, KAKENHI-PLANNED-22118002, KAKENHI-PROJECT-22591045, KAKENHI-PROJECT-23249051, KAKENHI-PROJECT-23390257, KAKENHI-PROJECT-23591396
[Journal Article] Two types of C/EBPa mutations play distinct roles in leukemogenesis: Lessons from clinical data and BMT models2011
- Author(s)
  Kato N., Kitaura J., Doki N., Komeno Y., Watanabe-Okochi N., Togami K., Nakahara F., Oki T., Enomoto Y., Fukuchi Y., Nakajima H., Harada Y., Harada H., Kitamura T.
- Journal Title
  
  Blood 117
  
  Pages: 221-233
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] TIM1 is an endogenous ligand for LMIR5/CD300b : LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury.2010
- Author(s)
  Yamanishi, Y., Kitaura, J., Izawa, K., Kaitani, A., Komeno, Y., Nakamura, M., Yamazaki, S., Enomoto, Y., Oki, T., Akiba, H., Abe, T., Komori, T., Morikawa, Y., Kiyonari, H., Takai, T., Okumura, K., Kitamura, T.
- Journal Title
  
  J Exp Med. 207
  
  Pages: 1501-1511
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Hesl immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogeneou leukemia2010
- Author(s)
  Nakahara F., Sakata-Yanagimoto M., Komeno Y., Kato N., Uchida T., Haraguchi K., Kumano K., Harada Y., Harada H., Kitaura J., Ogawa S., Kurokawa M., Kitamura T., Chiba S.
- Journal Title
  
  Blood 115
  
  Pages: 2872-2881
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model2010
- Author(s)
  Komeno Y., Kitaura J., Watanabe-Okochi N., Kato N., Oki T., Nakahara F., Harada Y., Harada H., Shinkura R., Nagaoka H., Hayashi Y., Honjo T., Kitamura T.
- Journal Title
  
  Leukemia 24
  
  Pages: 1018-1024
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] AID-induced T-lymphoma or B-leukemia/lymphoma in a mouse BMT model.2010
- Author(s)
  Komeno, Y., Kitaura, J., Watanabe-Okochi, N., Kato, N., Oki, T., Nakahara, F., Harada, Y., Harada, H., Shinkura, R., Nagaoka, H., Hayashi, Y., Honjo, T., Kitamura, T.
- Journal Title
  
  Leukemia. 24
  
  Pages: 1018-1024
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Expression of ADAMTS4 in Ewing's sarcoma.2010
- Author(s)
  Minobe, K., Ono, R., Matsumine, A., Shibata-Minoshima, F., Izawa, K., Oki, T., Kitaura, J., Iino, T., Takita, J., Iwamoto, S., Hori, H., Komada, Y., Uchida, A., Hayashi, Y., Kitamura, T., Nosaka, T.
- Journal Title
  
  Int J Oncol. 37
  
  Pages: 569-581
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Hes1 immortalizes committed progenitors and plays a role in blastic crisis of chronic myelogenous leukemia.2010
- Author(s)
  Nakahara, F., Sakata-Yanagimoto, M., Komeno, Y., Kato, N., Haraguchi, K., Kumano, K., Harada, Y., Harada, H., Kitaura, J., Ogawa, S., Kurokawa, M., Kitamura, T., Chiba, S.
- Journal Title
  
  Blood. 115
  
  Pages: 2872-2881
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Characterization of leukocyte mono-immunoglobulin-like receptor 7 (LMIR7)/CLM-3 as an activating receptor : its similarities to and differences from LMIR4/CLM-5.2010
- Author(s)
  Enomoto, Y., Yamanishi, Y., Izawa, K., Kaitani, A., Takamatsu, R., Kajikawa, M., Takai, T., Kitamura, T., Kitaura, J.
- Journal Title
  
  J Bio Chem. 285
  
  Pages: 35274-35283
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Evidence that integrin τIIbυ3-dependent interaction of mast cells with fibrinogen exacerbates chronic inflammation.2009
- Author(s)
  Oki, T., Eto, K., Izawa, K., Yamanishi, Y., Inagaki, N., Frampton, J., Kitamura, T., Kitaura, J.
- Journal Title
  
  J Bio Chem. 284
  
  Pages: 31463-31472
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Molecular bases of myelodysplastic syndromes: lessons from animal models.2009
- Author(s)
  Komeno, Y., Kitaura, J., Kitamura, T.
- Journal Title
  
  J Cell Physiol. 219
  
  Pages: 529-534
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Possible involvement of RasGRP4 in leukemogenesis2009
- Author(s)
  Watanabe-Okochi N., Oki T., Komeno Y., Kato N., Yuji K., Ono R., Harada Y., Harada H., Hayashi Y., Nakajima H., Nosaka T., Kitaura J., Kitamura T.
- Journal Title
  
  Int J.Hematology 89
  
  Pages: 470-481
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1 : LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells.2009
- Author(s)
  Izawa, K., Kitaura, J., Yamanishi, Y., Matsuoka, T., Kaitani, A., Sugiuchi, M., Takahashi, M., Maehara, A., Enomoto, Y., Oki, T., Takai, T., Kitamura, T.
- Journal Title
  
  J Immunol. 183
  
  Pages: 925-936
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Enhanced expression of p210BCR/ABL and aberrant expression of Zfp423/ZNF423 induce blast crisis of chronic myelogenous leukemia.2009
- Author(s)
  Miyazaki, K., Yamasaki, N., Oda, H., Kuwata, T., Kanno, Y., Miyazaki, M., Komeno, Y., Kitaura, J., Honda, Z., Warming, S., Jenkins, N.A., Copeland, N.G., Kitamura, T., Nakamura, T., Honda, H.
- Journal Title
  
  Blood. 113
  
  Pages: 4702-4710
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Possible involvement of RasGRP4 in leukemogenesis.2009
- Author(s)
  Watanabe-Okochi, N., Oki, T., Komeno, Y., Kato, N., Yuji, K., Ono, R., Harada, Y., Harada, H., Hayashi, Y., Nakajima, H., Nosaka, T., Kitaura, J., Kitamura, T.
- Journal Title
  
  Int J Hematol. 89
  
  Pages: 470-481
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] 白血病、骨髄増殖性疾患、骨髄異形成症候群発症の分子メカニズム2009
- Author(s)
  北村俊雄、渡辺直子、米野由希子、加藤菜穂子、中原史雄、土岐典子、沖俊彦、北浦次郎
- Journal Title
  
  臨床血液 50
  
  Pages: 174-181
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model2008
- Author(s)
  Watanabe-Okochi N, Kitaura J., Ono R., Harada H., Harada Y., Nakajima H., Nosaka T., Inaba T., Kitamura T.
- Journal Title
  
  Blood 111
  
  Pages: 4297-4308
- Data Source
  KAKENHI-PROJECT-20249051
[Journal Article] AML1 mutations induced MDS and MDS/AML in a mouse BMT model.2008
- Author(s)
  Watanabe-Okochi, N., Kitaura, J., Ono, R., Harada, H., Harada, Y., Komeno, Y., Nakajima, H., Nosaka, T., Inaba, T., Kitamura, T.
- Journal Title
  
  Blood. 111
  
  Pages: 4297-4308
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype.2008
- Author(s)
  Kashiwakura, J., Xiao, W., Kitaura, J., Kawakami, Y., Maeda-Yamamoto, M., Pfeiffer, J.R., Wilson, B.S., Blank, U., Kawakami, T.
- Journal Title
  
  J Leukoc Biol. 84
  
  Pages: 357-367
- Data Source
  KAKENHI-PROJECT-20390279
[Journal Article] Dysregulation of Src family kinases in mast cells from epilepsy-resistant ASK versus epilepsy-prone EL mice.2007
- Author(s)
  北浦次郎
- Journal Title
  
  J. Immunol. 178
  
  Pages: 455-462
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390287
[Journal Article] IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion.2005
- Author(s)
  北浦次郎
- Journal Title
  
  Blood 105
  
  Pages: 3222-3229
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390287
[Journal Article] Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases.2005
- Author(s)
  北浦次郎
- Journal Title
  
  J. Immunol. 174
  
  Pages: 4495-4504
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17390287
[Journal Article] Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases
- Author(s)
  Kitaura, J, et. al.
- Journal Title
  
  J Immunol. 174
  
  Pages: 4495-4504
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390287
[Journal Article] IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion
- Author(s)
  Kitaura, J, et. al.
- Journal Title
  
  Blood. 105
  
  Pages: 3222-3229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390287
[Journal Article] Dysregulation of Src family kinases in mast cells from epilepsyresistant ASK versus epilepsy-prone EL mice
- Author(s)
  Kitaura, J, et. al.
- Journal Title
  
  J Immunol. 178
  
  Pages: 455-462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390287
[Presentation] Ceramide-CD300f interaction inhibits Mrgprb2-mediated pseudo-allergic drug reactions in mice.2017
- Author(s)
  Hatayama Tomoki, Takamori Ayako, Izawa Kumi, Maehara Akie, Isobe Masamichi, Kaitani Ayako, Uchida Shino, Nakano Nobuhiro, Maeda Keiko, Ando Tomoaki, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2017-12-07
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] Inhibition of allergic responses by ceramide-CD300f axis.2016
- Author(s)
  Jiro Kitaura
- Organizer
  Federation of American Societies for Experimental Biology (FASEB): IgE and Allergy: 50 Years and Onward
- Place of Presentation
  West Palm Beach, Florida (USA)
- Year and Date
  2016-07-25
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] CD300f suppresses LPS-induced skin inflammation.2016
- Author(s)
  Watanabe Daiki, Izawa Kumi, Kaitani Ayako, Maehara Akie, Isobe Masamichi, Takamori Ayako, Uchida Shino, Nakano Nobuhiro, Maeda Keiko, Ando Tomoaki, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Ceramide-CD300f interaction inhibits Mrgprb2-mediated pseudo-allergic drug reactions in mice.2016
- Author(s)
  Hatayama Tomoki, Takamori Ayako, Izawa Kumi, Maehara Akie, Isobe Masamichi, Kaitani Ayako, Uchida Shino, Nakano Nobuhiro, Maeda Keiko, Ando Tomoaki, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] A critical role of ceramide-CD300f interaction in septic peritonitis.2016
- Author(s)
  Izawa Kumi, Maehara Akie, Isobe Masamichi, Kaitani Ayako, Nakano Nobuhiro, Maeda Keiko, Takamori Ayako, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2016-12-06
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Leukocyte mono-immunoglobulin-like receptor 6 (LMIR6) is an activating receptor expressed in patrolling monocytes.2016
- Author(s)
  Isobe Masamichi, Takamori Ayako, Izawa Kumi, Maehara Akie, Kaitani Ayako, Uchida Shino, Nakano Nobuhiro, Maeda Keiko, Ando Tomoaki, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] The regulatory role of a novel activating receptor in mast cell- and IgE-dependent anaphylaxis2016
- Author(s)
  Jiro Kitaura
- Organizer
  31st Symposium of the Collegium Internationale Allergologicum
- Place of Presentation
  Charleston, South Carolina（USA）
- Year and Date
  2016-04-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] 敗血症性腹膜炎におけるセラミド-CD300fシグナルの役割2016
- Author(s)
  伊沢久未、奥村康、北浦次郎
- Organizer
  第９回セラミド研究会学術集会
- Place of Presentation
  東京ユビキタス協創広場CANVAS、東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] The role of leukocyte mono-immunoglobulin-like receptor 8 (LMIR8)/CLM-6 in plasmacytoid dendritic cell (pDC)2016
- Author(s)
  Kaitani Ayako, Izawa Kumi, Maehara Akie, Isobe Masamichi, Takamori Ayako, Uchida Shino, Nakano Nobuhiro, Maeda Keiko, Ando Tomoaki, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第45回日本免疫学会
- Place of Presentation
  Okinawa Convention Center・Laguna Garden Hotel、沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] マスト細胞に発現する活性化型受容体LMIR7のアレルギー反応にける役割2016
- Author(s)
  伊沢久未、奥村康、北村俊雄、北浦次郎
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京国際フォーラム、東京
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Inhibition of allergic responses by ceramide-CD300f axis.2016
- Author(s)
  Jiro Kitaura
- Organizer
  Federation of American Societies for Experimental Biology (FASEB): IgE and Allergy: 50 Years and Onward
- Place of Presentation
  West Palm Beach, Florida (USA)
- Year and Date
  2016-07-25
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] 敗血症性腹膜炎におけるセラミド-CD300fシグナルの役割2016
- Author(s)
  伊沢久未、奥村康、北浦次郎
- Organizer
  第９回セラミド研究会学術集会
- Place of Presentation
  東京ユビキタス協創広場CANVAS、東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] マウスおよびヒトLMIR3のリガンド同定と機能解析2015
- Author(s)
  伊沢久未、奥村康、北村俊雄、北浦次郎
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] The novel role of LMIR7/CLM-3 in mast cell- and IgE-dependent anaphylaxis2015
- Author(s)
  Isobe Masamichi, Izawa Kumi, Maehara Akie, Matsukawa Toshihiro, Kaitani Akie, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第44回日本免疫学会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation.2015
- Author(s)
  Matsukawa Toshihiro, Izawa Kumi, Okumura Ko, Teshima Takanori, Kitamura Toshio, Kitaura Jiro
- Organizer
  THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS IMMUNOLOGY 2015
- Place of Presentation
  NEW ORLEANS (AMERICA)
- Year and Date
  2015-05-10
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] セラミドによるアレルギー性炎症の制御2015
- Author(s)
  北浦次郎
- Organizer
  第64 回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪 (東京）
- Year and Date
  2015-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] マウスおよびヒトLMIR3のリガンド同定と機能解析2015
- Author(s)
  伊沢久未、奥村康、北村俊雄、北浦次郎
- Organizer
  第64回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] セラミドを認識する抑制型受容体LMIR3/CD300fによるアレルギー・炎症の制御機構2015
- Author(s)
  北浦次郎
- Organizer
  第10回順天堂眼アレルギー研究会
- Place of Presentation
  ホテル東京ガーデンパレス
- Year and Date
  2015-03-04
- Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] セラミドによるアレルギー性炎症の制御2015
- Author(s)
  北浦次郎
- Organizer
  第64 回日本アレルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-05-28
- Invited
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] ペア型受容体LMIR/CD300による敗血症の制御機構2015
- Author(s)
  北浦次郎
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] 抑制型受容体LMIR3/CD300fによるアレルギー・炎症性疾患の制御メカニズム2015
- Author(s)
  北浦次郎
- Organizer
  第143回御茶ノ水木曜会
- Place of Presentation
  順天堂大学
- Year and Date
  2015-03-12
- Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Disrupting ceramide-LMIR3 interaction prevents bacterial sepsis by stimulating neutrophil recruitment2015
- Author(s)
  伊沢久未、磯部優理、奥村康、北村俊雄、北浦次郎
- Organizer
  第43回日本臨床免疫学会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Disrupting ceramide-LMIR3 interaction prevents bacterial sepsis by stimulating neutrophil recruitment2015
- Author(s)
  伊沢久未、磯部優理、奥村康、北村俊雄、北浦次郎
- Organizer
  第43回日本臨床免疫学会
- Place of Presentation
  神戸国際会議場兵庫県）
- Year and Date
  2015-10-22
- Data Source
  KAKENHI-PROJECT-15K15376
[Presentation] 抑制型レセプターLMIR3/CD300fの欠損はDSS腸炎を悪化させる2014
- Author(s)
  松川敏大、伊沢久未、北村俊雄、北浦次郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] ペア型受容体LMIR/CD300ファミリーとアレルギー・炎症2014
- Author(s)
  北浦次郎
- Organizer
  御茶ノ水がん学アカデミア第106回集会
- Place of Presentation
  順天堂大学
- Year and Date
  2014-10-22
- Invited
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] Disrupting ceramide-LMIR3 interaction prevents bacterial sepsis by stimulating neutrophil recruitment2014
- Author(s)
  Izawa Kumi, Isobe Masamichi, Matsukawa Toshihiro, Maehara Akie, Takahashi Mariko, Kaitani Ayako, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第43回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] LMIR3/CD300f deficiency aggravates DSS-induced colitis2014
- Author(s)
  Matsukawa Toshihiro, Izawa Kumi, Isobe Masamichi, Takahashi Mariko, Maehara Akie, Kaitani Ayako, Okumura Ko, Kitamura Toshio, Kitaura Jiro
- Organizer
  第43回日本免疫学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-26293231
[Presentation] ペア型免疫レセプターLMIR/CD300とアレルギー<脂質セラミドを認識する抑制型レセプターLMIR3/CD300f>2013
- Author(s)
  北浦次郎
- Organizer
  平成24年度アトピー疾患研究センター(ARC)研究プロジェクト評価会議
- Place of Presentation
  東京・順天堂大学大学院医学研究科アトピー疾患研究センター
- Year and Date
  2013-03-25
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] 抑制型レセプターLMIR3/CD300fは細胞外脂質セラミドを認識してマスト細胞の活性化と付随するアレルギー反応を抑制する2013
- Author(s)
  北浦次郎
- Organizer
  第22回東京免疫フォーラム
- Place of Presentation
  東京・東京大学医科学研究
- Year and Date
  2013-03-14
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] セラミドとマスト細胞<LMIR3/CD300fはセラミドを認識してマスト細胞の活性化を抑制する>2013
- Author(s)
  北浦次郎
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京・ホテルニューオータニ
- Year and Date
  2013-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] Molecular Mechanisms of blast crisis in chronic myelogenous leukemia caused by upregulation of Hes12012
- Author(s)
  中原史雄, 北浦次郎, 川畑公人, 内田智之,鍵山侑希, 井上大地, 戸上勝仁, 沖俊彦, 原田結花 , 原田浩徳 , 北村俊雄
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23249051
[Presentation] Leukemogenesis induced by C-terminal mutations in the basic leucine zipper domain of C/EBPα2012
- Author(s)
  戸上勝仁, 北浦次郎, 井上大地, 鍵山侑希, 内田智之, 西村耕太郎, 土岐典子, 加藤菜穂子, 中原史雄, 沖俊彦, 原田結花, 原田浩徳, 北村俊雄
- Organizer
  第74回日本血液学会
- Place of Presentation
  京都国際会館
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23249051
[Presentation] LMIR3/CD300f negatively regulates mast cell-dependent allergic responses2012
- Author(s)
  Kitaura Jiro
- Organizer
  The International Symposium-Allergy and Inflammation
- Place of Presentation
  韓国・ソウル・Kyung Hee University
- Year and Date
  2012-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] LMIR5/CD300bのリガンド(TIM1)同定と(腎虚血における)機能解析2011
- Author(s)
  北浦次郎
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会館(招待講演)
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] CD300/LMIRファミリーとマスト細胞2011
- Author(s)
  北浦次郎
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京グランドプリンスホテル新高輪
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23249051
[Presentation] CD300/LMIRファミリーとマスト細胞2011
- Author(s)
  北浦次郎
- Organizer
  第61回日本アレルギー学会秋季学術大会
- Place of Presentation
  グランドプリンスホテル新高輪(招待講演)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] LMIR5/CD300bのリガンド(TIM1)同定と(腎虚血における)機能解析2011
- Author(s)
  北浦次郎
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都国立京都国際会館
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-23249051
[Presentation] LMIR5/CD300bのリガンド(TIM1)同定と(腎虚血における)機能解析2011
- Author(s)
  北浦次郎
- Organizer
  第84回日本生化学会大会・シンポジウム炎症応答制御分子研究の最前線
- Place of Presentation
  京都・国立京都国際館
- Year and Date
  2011-09-22
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] Molecular Basis for AML2010
- Author(s)
  Kitamura T., Nakahara F., Kato N., Watanabe-Okochi N., Komeno Y., Doki N., Togami K., Uchida T., Kagiyama Y., Inoue D., Enomoto Y., Oki T., Harada H., Kitaura J.
- Organizer
  MDS and MPN 第39回国際実験血液学会
- Place of Presentation
  メルボルン(招待講演)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] A FUNCTIONAL ANALYSIS OF microRNA ABERRANTLY EXPRESSED IN LEUKEMIC CELLS.2010
- Author(s)
  榎本豊、北浦次郎、園木孝志、中熊秀喜、北村俊雄
- Organizer
  日本遺伝子治療学会学術集会ポスター
- Place of Presentation
  宇都宮
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Leukocyte mono-Ig like receptor (LMIR)/CD300とマスト細胞2010
- Author(s)
  北浦次郎
- Organizer
  日本アレルギー学会シンポジウム
- Place of Presentation
  東京(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Leukocyte mono-Ig like receptor (LMIR)/CD300と炎症・アレルギー2010
- Author(s)
  北浦次郎
- Organizer
  小児アレルギー同好会
- Place of Presentation
  東京(口演)
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] TIM1 is an endogenous ligand for LMIR5/CD300b : LMIR5 deficiency ameliorates mouse kidney ischemia/reperfusion injury2010
- Author(s)
  山西吉典、北浦次郎、伊沢久未、北村俊雄
- Organizer
  国際免疫学会議
- Place of Presentation
  神戸(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Comparative analysis of leukocyte mono-Ig-like receptor 7 (LMIR7)/CLM-3 with LMIR4/CLM-5 as an activating receptor: lessons from association with FcRgamma2010
- Author(s)
  榎本豊、北浦次郎、山西吉典、伊沢久未、高井俊行、北村俊雄
- Organizer
  国際免疫学会議
- Place of Presentation
  神戸(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Leukocyte mono-Ig like receptor (LMIR)/CD300とマスト細胞2010
- Author(s)
  北浦次郎
- Organizer
  第60回日本アレルギー学会秋期学述大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2010-11-26
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Leukocyte mono-Ig like receptor(LMIR)/CD300と炎症・アレルギー2010
- Author(s)
  北浦次郎
- Organizer
  第72回小児アレルギー同好会
- Place of Presentation
  ホテルグランドパレス
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] ヒトLMIR/CD300ファミリー分子の解析:CD300CはFcRgammaと会合して活性化シグナルを伝達する2009
- Author(s)
  高橋まり子、北浦次郎、山西吉典、伊沢久未、北村俊雄
- Organizer
  日本免疫学会
- Place of Presentation
  大阪(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] 活性化レセプターLMIR7とLMIR4の比較解析:FcRgammaとの会合から得られた知見2009
- Author(s)
  榎本豊、北浦次郎、山西吉典、伊沢久未、北村俊雄
- Organizer
  日本免疫学会、ポスター
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] LMIR3ノックアウトマウスの解析;LMIR3欠損はマウス腹膜炎モデルにおける致死率を改善する2009
- Author(s)
  伊沢久未、北浦次郎、山西吉典、北村俊雄
- Organizer
  日本免疫学会
- Place of Presentation
  大阪(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Analysis of C/EBPA mutations in AML, MDS by a mouse BMT model2009
- Author(s)
  加藤菜穂子、米野由希子、渡辺直子、中原史雄、土岐典子、原田浩徳、原田結花、北浦次郎、北村俊雄
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] Hes1 confers self-renewal capability on committed progenitors and induces CML BC-like disease2009
- Author(s)
  中原史雄、北浦次郎、坂田-柳本麻美子、米野由希子、加藤菜穂子、黒川峰夫、千葉滋、北村俊雄
- Organizer
  第71回日本血液学会学術集会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1:LMIR3 augments LPS response through association with FcRgamma in mast cells2009
- Author(s)
  前原秋絵、北浦次郎、山西吉典、伊沢久未、北村俊雄
- Organizer
  日本免疫学会、ポスター
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] LMIR5のリガンドとしてTIM1およびTIM4を同定した2009
- Author(s)
  山西吉典、北浦次郎、伊沢久未、北村俊雄
- Organizer
  日本免疫学会
- Place of Presentation
  大阪(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] LMIR8/CLM-6はpDCマーカーである2009
- Author(s)
  貝谷綾子、北浦次郎、山西吉典、伊沢久未、北村俊雄
- Organizer
  日本免疫学会
- Place of Presentation
  大阪(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] BMTモデルを用いたAID高発現による白血病・リンパ腫の解析2008
- Author(s)
  米野由希子、北浦次郎、渡辺(大河内)直子、加藤菜穂子、沖俊彦、本庶佑、北村俊雄
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] 活性化レセプターのLMIR6は末梢血の樹状細胞に高発現する2008
- Author(s)
  杉内正弘、北浦次郎、山西吉典、伊沢久未、沖俊彦、高井俊行、北村俊雄
- Organizer
  日本免疫学会総会、ポスター
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] 活性型レセプターLMIR5の機能解析:マウスおよびヒトLMIR5の相違2008
- Author(s)
  山西吉典、北浦次郎、伊沢久未、沖俊彦、北村俊雄
- Organizer
  麒麟塾
- Place of Presentation
  東京(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] 活性化レセプターLMIR7の機能解析2008
- Author(s)
  榎本豊、北浦次郎、山西吉典、伊沢久未、沖俊彦、高井俊行、北村俊雄
- Organizer
  日本免疫学会総会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] LMIR3はマスト細胞において細胞内領域ITIMを介した抑制化シグナルとITAMを有するFcRgammaとの会合を介した活性化シグナルを伝達する2008
- Author(s)
  伊沢久未、北浦次郎、山西吉典、松岡孝幸、沖俊彦、高井俊行、北村俊雄
- Organizer
  日本免疫学会総会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] Overexpression of AID causes both T and B lymphoma in a mouse BMT model2008
- Author(s)
  Komeno Y., Kitaura J., Watanabe-Okochi N., Kato N., Oki T., Honjo T., 北村俊雄
- Organizer
  ISEH 37th Annual Scientific Meeting
- Place of Presentation
  ボストン(Poster)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] マウス骨髄移植モデルにおいて、Evi1はMDS/AMLを誘発する2008
- Author(s)
  渡辺(大河内)直子、北浦次郎、原田浩徳、米野由希子、加藤菜穂子、小埜良一、野阪哲哉、中島秀明、北村俊雄
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20249051
[Presentation] Analysis of mouse LMIR5/CLM-7 as an activating receptor : differential regulation of LMIR5/CLM-7 in mouse versus human cells.2008
- Author(s)
  山西吉典, 北浦次郎, 伊沢久未, 北村俊雄
- Organizer
  The 15^<th> East Asia Joint Conference
- Place of Presentation
  韓国ソウル(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] 可溶性LMIR5はLPSによる炎症反応を増強する2008
- Author(s)
  山西吉典、北浦次郎、伊沢久未、北村俊雄
- Organizer
  日本免疫学会
- Place of Presentation
  京都(口演)
- Data Source
  KAKENHI-PROJECT-20390279
[Presentation] IgEを介したオートクライン機構によるマスト細胞の遊走2005
- Author(s)
  北浦次郎
- Organizer
  日本免疫学会
- Place of Presentation
  横浜
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390287
[Presentation] IgE- and IgE+Ag-mediated migration of mast cells in an autocrine/paracrine fashion2005
- Author(s)
  Kitaura, J, et. al.
- Organizer
  Proceedings of the Japanese Society for Immunology
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390287
[Presentation] セラミドとマスト細胞＜LMIR3/CD300fはセラミドを認識してマスト細胞の活性化を抑制する>
- Author(s)
  北浦次郎
- Organizer
  第63回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京・ホテルニューオータニ
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] LMIR3/CD300f negatively regulates mast cell-dependent allergic responses
- Author(s)
  北浦次郎
- Organizer
  The International Symposium-Allergy and　Inflammation
- Place of Presentation
  韓国　ソウル　Kyung Hee University
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] 抑制型レセプターLMIR3/CD300fは細胞外脂質セラミドを認識してマスト細胞の活性化と付随するアレルギー反応を抑制する
- Author(s)
  北浦次郎
- Organizer
  第22回東京免疫フォーラム
- Place of Presentation
  東京　東大医科学研究所
- Invited
- Data Source
  KAKENHI-PROJECT-23390257
[Presentation] ペア型免疫レセプターLMIR/CD300とアレルギー＜脂質セラミドを認識する抑制型レセプターLMIR3/CD300f>
- Author(s)
  北浦次郎
- Organizer
  平成24年度アトピー疾患研究センター(ARC)研究プロジェクト評価会議
- Place of Presentation
  東京　順天堂大学大学院医学研究科アトピー疾患研究センター
- Invited
- Data Source
  KAKENHI-PROJECT-23390257

1. KITAMURA Toshio (20282527)

# of Collaborated Projects: 9 results

# of Collaborated Products: 83 results
2. NAKAO Kazuki (20217657)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YUJI Koichiro (50396868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TOJO Arinobu (00211681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAHARA Fumio (80581181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. Fukuyama Tomofusa (10300906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 井上大地 (80735746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OKOCHI Naoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
10. MAEDA Keiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. OHTSUKA Yoshikazu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 栗原由紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 栗原裕基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 熊野恵城

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 黒川峰夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 吉見昭秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
18. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 奥村康

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 稲葉俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 長町安希子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 伊沢久未

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
23. 中野信浩

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# of Collaborated Products: 3 results
24. 清水俊明

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# of Collaborated Products: 2 results
25. 山西吉典

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# of Collaborated Products: 1 results
26. 麻生範雄

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27. 服部浩一

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28. HEISSIG Beate

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# of Collaborated Products: 1 results
29. 永江玄太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 西山千春

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITAURA JIRO 北浦 次郎

KITAURA Jiro 北浦 次郎

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Identification of novel mutations in patients with pyroptosis-associated rare disease and clarification of the pathogenesisPrincipal InvestigatorOngoing

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Analysis of the mechanism by which lipid-recognizing paired immnue receptors regulate inflammationPrincipal InvestigatorOngoing

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The development of anti-allergy therapies targeting several inhibitory receptorsPrincipal Investigator

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Comprehensive elucidation of MDS (myelodysplastic syndromes) pathogenesis

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Analysis of the mechanisms by which mast cell activation is regulated by paired receptors LMIR3 and LMIR7Principal Investigator

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Integrative elucidation of molecular mechanisms for leukemogenesis: Identification and analyses of mutations with novel categories.

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What is a ligand fro LMIR, regulating allery and inflammation?Principal Investigator

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ペア型免疫レセプターファミリーLMIR/CLM/MAIRの機能解析とリガンド同定

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Toward the comprehensive understanding of molecular mechanisms of hematopoietic malignancies

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Analysis of in vivo functions of LMIR3/4/5Principal Investigator

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アポトーシス細胞を認識する新しいレセプターLMIR3/4の機能解析

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What is the function of integrin allb in mast cell?Principal Investigator

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[Book] マスト細胞の活性化とLMIR3(「抑制型レセプターであるLMIR3はマスト細胞においてFcR.と会合し、リポポリサッカライドによる反応を増強する」)532010

Author(s)

Publisher

KITAURA JIRO 北浦次郎

KITAURA Jiro 北浦次郎

[Journal Article] A C-terminal mutant of C/EBP (C/EBPa-Cm) down-regulates the Csf1r, a potent accelerator in the progression of AML with C/EBPa-Cm2015